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Conserved domains on  [gi|29243940|ref|NP_808253|]
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IQ domain-containing protein J [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IQCJ-SCHIP1 super family cl21023
Fusion protein IQCJ-SCHIP1 with IQ-like motif; This is a family of eukaryotic fusion proteins. ...
 4-99 8.93e-49

Fusion protein IQCJ-SCHIP1 with IQ-like motif; This is a family of eukaryotic fusion proteins. It bridges two adjacent genes that encode distinct proteins, IQCJ, a novel IQ motif containing protein and SCHIP1, a schwannomin interacting protein. It contains a unique calmodulin-binding IQ motif at the N-terminus not shared with its shorter isoform SCHIP1, suggesting a distinctive function for this protein. It is localized to cytoplasm and actin-rich regions, and in differentiated PC12 cells is seen in neurite extensions. the exact physiological function is unclear.


The actual alignment was detected with superfamily member pfam15157:

Pssm-ID: 434507  Cd Length: 153  Bit Score: 152.21  E-value: 8.93e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29243940     4 EELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLS 83
Cdd:pfam15157   1 EELKRLQNPLEQVNDGKYLLENHQLAMDVENNIEKYHLNLQPLESKVKIIQRAWREYLQRQEPLEKRSPSPPSVSSEKLS 80

                          90
                  ....*....|....*.
gi 29243940    84 SSVSMNTFSDSSTPVS 99
Cdd:pfam15157  81 SSVSMNTFSDSSTPVS 96
 
Name Accession Description Interval E-value
IQCJ-SCHIP1 pfam15157
Fusion protein IQCJ-SCHIP1 with IQ-like motif; This is a family of eukaryotic fusion proteins. ...
 4-99 8.93e-49

Fusion protein IQCJ-SCHIP1 with IQ-like motif; This is a family of eukaryotic fusion proteins. It bridges two adjacent genes that encode distinct proteins, IQCJ, a novel IQ motif containing protein and SCHIP1, a schwannomin interacting protein. It contains a unique calmodulin-binding IQ motif at the N-terminus not shared with its shorter isoform SCHIP1, suggesting a distinctive function for this protein. It is localized to cytoplasm and actin-rich regions, and in differentiated PC12 cells is seen in neurite extensions. the exact physiological function is unclear.


Pssm-ID: 434507  Cd Length: 153  Bit Score: 152.21  E-value: 8.93e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29243940     4 EELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLS 83
Cdd:pfam15157   1 EELKRLQNPLEQVNDGKYLLENHQLAMDVENNIEKYHLNLQPLESKVKIIQRAWREYLQRQEPLEKRSPSPPSVSSEKLS 80

                          90
                  ....*....|....*.
gi 29243940    84 SSVSMNTFSDSSTPVS 99
Cdd:pfam15157  81 SSVSMNTFSDSSTPVS 96
 
Name Accession Description Interval E-value
IQCJ-SCHIP1 pfam15157
Fusion protein IQCJ-SCHIP1 with IQ-like motif; This is a family of eukaryotic fusion proteins. ...
 4-99 8.93e-49

Fusion protein IQCJ-SCHIP1 with IQ-like motif; This is a family of eukaryotic fusion proteins. It bridges two adjacent genes that encode distinct proteins, IQCJ, a novel IQ motif containing protein and SCHIP1, a schwannomin interacting protein. It contains a unique calmodulin-binding IQ motif at the N-terminus not shared with its shorter isoform SCHIP1, suggesting a distinctive function for this protein. It is localized to cytoplasm and actin-rich regions, and in differentiated PC12 cells is seen in neurite extensions. the exact physiological function is unclear.


Pssm-ID: 434507  Cd Length: 153  Bit Score: 152.21  E-value: 8.93e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29243940     4 EELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLS 83
Cdd:pfam15157   1 EELKRLQNPLEQVNDGKYLLENHQLAMDVENNIEKYHLNLQPLESKVKIIQRAWREYLQRQEPLEKRSPSPPSVSSEKLS 80

                          90
                  ....*....|....*.
gi 29243940    84 SSVSMNTFSDSSTPVS 99
Cdd:pfam15157  81 SSVSMNTFSDSSTPVS 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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