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Conserved domains on  [gi|228008340|ref|NP_808424|]
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procollagen galactosyltransferase 2 isoform 1 precursor [Mus musculus]

Protein Classification

glycosyltransferase family 25 protein( domain architecture ID 10616542)

glycosyltransferase family 25 protein may be involved in lipopolysaccharide (LPS) biosynthesis, facilitating the transfer of one of a variety of sugars onto a growing LPS chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_25 super family cl01298
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of ...
 340-525 4.32e-39

Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.


The actual alignment was detected with superfamily member pfam01755:

Pssm-ID: 470150  Cd Length: 200  Bit Score: 142.58  E-value: 4.32e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  340 FDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLkawNIEMLPGYRDPYSSRPLTRGEIGCFLSHFSV 419
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPNHLL---FKLYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  420 WKEVIDRELEKTLVIEDDVRFEHQFKRKLMKLMediDKAQLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSY----- 494
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLL---KEINELEFLRLGEWLKTRFDPNDKFIVRLETFLMDSKKFkrtpi 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 228008340  495 ----------------WTLGYAISLEGAQKLVGADPFGKMlPVDEFL 525
Cdd:pfam01755 155 adygnrafyllksghaGTAGYLITPKAAKKLLKYSKNWPL-PVDDLM 200
Glyco_tranf_2_4 pfam13704
Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative ...
 61-174 1.50e-07

Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative glucosyltransferases,


:

Pssm-ID: 433416 [Multi-domain]  Cd Length: 97  Bit Score: 49.55  E-value: 1.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340   61 RNAAHTLPYFLGCLERLDYPksrmAIWAATDHNVDNTTEILREWlKSVQRLYHyvewrpmnepesypdeigPKHWPNSRF 140
Cdd:pfam13704   1 RNEADILPQWLAHHLALGFD----HIYVYDNGSDDGTAEILARL-PDVSILRS------------------DLSYKDARF 57

                          90       100       110
                  ....*....|....*....|....*....|....
gi 228008340  141 SHVMklRQAALRTAreKWSDYILFIDVDNFLTNP 174
Cdd:pfam13704  58 QVDW--RNALLARY--AEADWVLVVDADEFLVYP 87
 
Name Accession Description Interval E-value
Glyco_transf_25 pfam01755
Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to ...
 340-525 4.32e-39

Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.


Pssm-ID: 366794  Cd Length: 200  Bit Score: 142.58  E-value: 4.32e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  340 FDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLkawNIEMLPGYRDPYSSRPLTRGEIGCFLSHFSV 419
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPNHLL---FKLYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  420 WKEVIDRELEKTLVIEDDVRFEHQFKRKLMKLMediDKAQLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSY----- 494
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLL---KEINELEFLRLGEWLKTRFDPNDKFIVRLETFLMDSKKFkrtpi 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 228008340  495 ----------------WTLGYAISLEGAQKLVGADPFGKMlPVDEFL 525
Cdd:pfam01755 155 adygnrafyllksghaGTAGYLITPKAAKKLLKYSKNWPL-PVDDLM 200
COG3306 COG3306
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope ...
 364-578 9.66e-34

Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442535 [Multi-domain]  Cd Length: 238  Bit Score: 128.97  E-value: 9.66e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 364 EQEIEVKIVEAVDGKALNTSQLKAWNiemlPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRFEHQ 443
Cdd:COG3306   24 RLGLDFEFFDAVDGRDLSEEELARYD----RAKALRRYGRPLTPGEIGCFLSHRKAWQKIVESGLPYALILEDDVILSPD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 444 FKrklmKLMEDIDKAQLDWELIYIGRKRMQVKEPEKAVPNVVN--LVEADYSYW-TLGYAISLEGAQKLVG-ADPFGkmL 519
Cdd:COG3306  100 FA----EVLEALAWLPADWDIVKLETSKRKVFLGRRKIKKLGGyrLVRPYSPPLgTAGYLISRKAAKKLLAlLEPID--R 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 228008340 520 PVDEFLpimynkhpvaeykEYYESRDLKAFSAEPLLIYPThytgqpgylSDTETSTIWD 578
Cdd:COG3306  174 PVDDFL-------------FRFWLHGLRVYQVRPALVIQD---------SGLLGSTIEA 210
Glyco_transf_25 cd06532
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of ...
 361-525 1.13e-25

Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.


Pssm-ID: 133474  Cd Length: 128  Bit Score: 102.29  E-value: 1.13e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 361 TLYEQEIEVKIVEAVDGKALNTSQLKAwnieMLPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRF 440
Cdd:cd06532   20 QLAALGLDFEFFDAVDGKDLSEEELAA----LYDALFLPRYGRPLTPGEIGCFLSHYKLWQKIVESNLEYALILEDDAIL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 441 EHqfkrklmklmedidkaqldweliyigrkrmqvkepekavpnvvnlveadysYWTLGYAISLEGAQKLVGADPFgKMLP 520
Cdd:cd06532   96 DP---------------------------------------------------DGTAGYLVSRKGAKKLLAALEP-IDLP 123


                 ....*
gi 228008340 521 VDEFL 525
Cdd:cd06532  124 VDVFL 128
Glyco_tranf_2_4 pfam13704
Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative ...
 61-174 1.50e-07

Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative glucosyltransferases,


Pssm-ID: 433416 [Multi-domain]  Cd Length: 97  Bit Score: 49.55  E-value: 1.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340   61 RNAAHTLPYFLGCLERLDYPksrmAIWAATDHNVDNTTEILREWlKSVQRLYHyvewrpmnepesypdeigPKHWPNSRF 140
Cdd:pfam13704   1 RNEADILPQWLAHHLALGFD----HIYVYDNGSDDGTAEILARL-PDVSILRS------------------DLSYKDARF 57

                          90       100       110
                  ....*....|....*....|....*....|....
gi 228008340  141 SHVMklRQAALRTAreKWSDYILFIDVDNFLTNP 174
Cdd:pfam13704  58 QVDW--RNALLARY--AEADWVLVVDADEFLVYP 87
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 56-185 1.57e-07

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 51.35  E-value: 1.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  56 VVVLARNAAHTLPYFLGCLERLDYPKSRmaIWAATDHNVDNTTEILREWLKSVQRLYHYVewrpmnepesypdeigpkHW 135
Cdd:cd00761    1 VIIPAYNEEPYLERCLESLLAQTYPNFE--VIVVDDGSTDGTLEILEEYAKKDPRVIRVI------------------NE 60

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 228008340 136 PNSRFSHVmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLMIVENK 185
Cdd:cd00761   61 ENQGLAAA---RNAGLKAAR---GEYILFLDADDLLL-PDWLERLVAELL 103
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 42-181 1.02e-06

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 50.90  E-value: 1.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  42 VAFPESPPQKPTVFVVVLARNAAHTLPYFLGCLERLDYPKSRMAIWAATDHNVDNTTEILREWLKSVQRLyHYVEwRPmn 121
Cdd:COG1215   19 ARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVIVVDDGSTDETAEIARELAAEYPRV-RVIE-RP-- 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 122 epesypdeigpkhwPNSRFSHVmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLMI 181
Cdd:COG1215   95 --------------ENGGKAAA---LNAGLKAAR---GDIVVFLDADTVLD-PDWLRRLV 133
 
Name Accession Description Interval E-value
Glyco_transf_25 pfam01755
Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to ...
 340-525 4.32e-39

Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.


Pssm-ID: 366794  Cd Length: 200  Bit Score: 142.58  E-value: 4.32e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  340 FDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLkawNIEMLPGYRDPYSSRPLTRGEIGCFLSHFSV 419
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPNHLL---FKLYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  420 WKEVIDRELEKTLVIEDDVRFEHQFKRKLMKLMediDKAQLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSY----- 494
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLL---KEINELEFLRLGEWLKTRFDPNDKFIVRLETFLMDSKKFkrtpi 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 228008340  495 ----------------WTLGYAISLEGAQKLVGADPFGKMlPVDEFL 525
Cdd:pfam01755 155 adygnrafyllksghaGTAGYLITPKAAKKLLKYSKNWPL-PVDDLM 200
COG3306 COG3306
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope ...
 364-578 9.66e-34

Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442535 [Multi-domain]  Cd Length: 238  Bit Score: 128.97  E-value: 9.66e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 364 EQEIEVKIVEAVDGKALNTSQLKAWNiemlPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRFEHQ 443
Cdd:COG3306   24 RLGLDFEFFDAVDGRDLSEEELARYD----RAKALRRYGRPLTPGEIGCFLSHRKAWQKIVESGLPYALILEDDVILSPD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 444 FKrklmKLMEDIDKAQLDWELIYIGRKRMQVKEPEKAVPNVVN--LVEADYSYW-TLGYAISLEGAQKLVG-ADPFGkmL 519
Cdd:COG3306  100 FA----EVLEALAWLPADWDIVKLETSKRKVFLGRRKIKKLGGyrLVRPYSPPLgTAGYLISRKAAKKLLAlLEPID--R 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 228008340 520 PVDEFLpimynkhpvaeykEYYESRDLKAFSAEPLLIYPThytgqpgylSDTETSTIWD 578
Cdd:COG3306  174 PVDDFL-------------FRFWLHGLRVYQVRPALVIQD---------SGLLGSTIEA 210
Glyco_transf_25 cd06532
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of ...
 361-525 1.13e-25

Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.


Pssm-ID: 133474  Cd Length: 128  Bit Score: 102.29  E-value: 1.13e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 361 TLYEQEIEVKIVEAVDGKALNTSQLKAwnieMLPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRF 440
Cdd:cd06532   20 QLAALGLDFEFFDAVDGKDLSEEELAA----LYDALFLPRYGRPLTPGEIGCFLSHYKLWQKIVESNLEYALILEDDAIL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 441 EHqfkrklmklmedidkaqldweliyigrkrmqvkepekavpnvvnlveadysYWTLGYAISLEGAQKLVGADPFgKMLP 520
Cdd:cd06532   96 DP---------------------------------------------------DGTAGYLVSRKGAKKLLAALEP-IDLP 123


                 ....*
gi 228008340 521 VDEFL 525
Cdd:cd06532  124 VDVFL 128
Glyco_tranf_2_4 pfam13704
Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative ...
 61-174 1.50e-07

Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative glucosyltransferases,


Pssm-ID: 433416 [Multi-domain]  Cd Length: 97  Bit Score: 49.55  E-value: 1.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340   61 RNAAHTLPYFLGCLERLDYPksrmAIWAATDHNVDNTTEILREWlKSVQRLYHyvewrpmnepesypdeigPKHWPNSRF 140
Cdd:pfam13704   1 RNEADILPQWLAHHLALGFD----HIYVYDNGSDDGTAEILARL-PDVSILRS------------------DLSYKDARF 57

                          90       100       110
                  ....*....|....*....|....*....|....
gi 228008340  141 SHVMklRQAALRTAreKWSDYILFIDVDNFLTNP 174
Cdd:pfam13704  58 QVDW--RNALLARY--AEADWVLVVDADEFLVYP 87
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 56-185 1.57e-07

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 51.35  E-value: 1.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  56 VVVLARNAAHTLPYFLGCLERLDYPKSRmaIWAATDHNVDNTTEILREWLKSVQRLYHYVewrpmnepesypdeigpkHW 135
Cdd:cd00761    1 VIIPAYNEEPYLERCLESLLAQTYPNFE--VIVVDDGSTDGTLEILEEYAKKDPRVIRVI------------------NE 60

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 228008340 136 PNSRFSHVmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLMIVENK 185
Cdd:cd00761   61 ENQGLAAA---RNAGLKAAR---GEYILFLDADDLLL-PDWLERLVAELL 103
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 42-181 1.02e-06

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 50.90  E-value: 1.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  42 VAFPESPPQKPTVFVVVLARNAAHTLPYFLGCLERLDYPKSRMAIWAATDHNVDNTTEILREWLKSVQRLyHYVEwRPmn 121
Cdd:COG1215   19 ARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVIVVDDGSTDETAEIARELAAEYPRV-RVIE-RP-- 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 122 epesypdeigpkhwPNSRFSHVmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLMI 181
Cdd:COG1215   95 --------------ENGGKAAA---LNAGLKAAR---GDIVVFLDADTVLD-PDWLRRLV 133
GT_2_like_e cd04192
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 56-101 1.62e-05

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133035 [Multi-domain]  Cd Length: 229  Bit Score: 46.51  E-value: 1.62e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 228008340  56 VVVLARNAAHTLPYFLGCLERLDYPKSRMAIWAATDHNVDNTTEIL 101
Cdd:cd04192    1 VVIAARNEAENLPRLLQSLSALDYPKEKFEVILVDDHSTDGTVQIL 46
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 45-113 2.29e-05

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 46.42  E-value: 2.29e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 228008340  45 PESPPQKPTVFVVVLARNAAHTLPYFLGCLERLDYPKSRMAIWAATDHNVDNTTEILREWLKSVQRLYH 113
Cdd:cd06439   22 LPDPAYLPTVTIIIPAYNEEAVIEAKLENLLALDYPRDRLEIIVVSDGSTDGTAEIAREYADKGVKLLR 90
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 56-189 4.76e-03

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 38.36  E-value: 4.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340  56 VVVLARNAAHTLPyflGCLE---RLDYPKSRmaIWAATDHNVDNTTEILREWLKSVQRLYHYVewrpmnepesypdeigp 132
Cdd:cd06423    1 IIVPAYNEEAVIE---RTIEsllALDYPKLE--VIVVDDGSTDDTLEILEELAALYIRRVLVV----------------- 58

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 228008340 133 KHWPNSRFSHVMKlrqAALRTARekwSDYILFIDVDNFLtNPQTLNLMIV---ENKTIVA 189
Cdd:cd06423   59 RDKENGGKAGALN---AGLRHAK---GDIVVVLDADTIL-EPDALKRLVVpffADPKVGA 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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