NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|30688693|ref|NP_849557|]
View 

Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11469168)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
65-200 1.09e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 67.25  E-value: 1.09e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  65 AVTSQEEPQHSEKKEEQIELMSEGEAIVDD------GSNKEKALAEANEAKAE-----GNKLFVNGLYEEALSKYAFALE 133
Cdd:COG4785  22 AAILLAALLFAAVLALAIALADLALALAAAalaaaaLAAERIDRALALPDLAQlyyerGVAYDSLGDYDLAIADFDQALE 101

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30688693 134 LVQELPEsielrsiCYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG4785 102 LDPDLAE-------AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAI 161
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
65-200 1.09e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 67.25  E-value: 1.09e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  65 AVTSQEEPQHSEKKEEQIELMSEGEAIVDD------GSNKEKALAEANEAKAE-----GNKLFVNGLYEEALSKYAFALE 133
Cdd:COG4785  22 AAILLAALLFAAVLALAIALADLALALAAAalaaaaLAAERIDRALALPDLAQlyyerGVAYDSLGDYDLAIADFDQALE 101

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30688693 134 LVQELPEsielrsiCYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG4785 102 LDPDLAE-------AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAI 161
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 25-200 4.17e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 61.54  E-value: 4.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693    25 SSPQPTETKQVDGDDSDgfetaSEREISDEEGEEDGTKNDAVTSQEEpqHSEKKEEQIELMSEGEaivddgsNKEKALAe 104
Cdd:TIGR00990  65 SKPKISKKERRKRKQAE-----KETEGKTEEKKSTAPKNAPVEPADE--LPEIDESSVANLSEEE-------RKKYAAK- 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693   105 aneAKAEGNKLFVNGLYEEALSKYAFALELVQElpesielrSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALV 184
Cdd:TIGR00990 130 ---LKEKGNKAYRNKDFNKAIKLYSKAIECKPD--------PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALN 198

                         170
                  ....*....|....*.
gi 30688693   185 RRAEAHEKLEHFEDAV 200
Cdd:TIGR00990 199 RRANAYDGLGKYADAL 214
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 148-179 1.38e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.51  E-value: 1.38e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 30688693    148 CYLNRGVCFLKLGKCEETIKECTKALELNPTY 179
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 105-203 2.12e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 44.39  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  105 ANEAKAEGNKLFVNGLYEEALSKYAFALELVqelPESIELrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALV 184
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLD---PNNAEL----YADRAQANIKLGNFTEAVADANKAIELDPSLAKAYL 74

                         90
                 ....*....|....*....
gi 30688693  185 RRAEAHEKLEHFEDAVTGL 203
Cdd:PLN03088  75 RKGTACMKLEEYQTAKAAL 93
TPR_1 pfam00515
Tetratricopeptide repeat;
149-179 1.01e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 1.01e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 30688693   149 YLNRGVCFLKLGKCEETIKECTKALELNPTY 179
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
65-200 1.09e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 67.25  E-value: 1.09e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  65 AVTSQEEPQHSEKKEEQIELMSEGEAIVDD------GSNKEKALAEANEAKAE-----GNKLFVNGLYEEALSKYAFALE 133
Cdd:COG4785  22 AAILLAALLFAAVLALAIALADLALALAAAalaaaaLAAERIDRALALPDLAQlyyerGVAYDSLGDYDLAIADFDQALE 101

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30688693 134 LVQELPEsielrsiCYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG4785 102 LDPDLAE-------AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAI 161
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 25-200 4.17e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 61.54  E-value: 4.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693    25 SSPQPTETKQVDGDDSDgfetaSEREISDEEGEEDGTKNDAVTSQEEpqHSEKKEEQIELMSEGEaivddgsNKEKALAe 104
Cdd:TIGR00990  65 SKPKISKKERRKRKQAE-----KETEGKTEEKKSTAPKNAPVEPADE--LPEIDESSVANLSEEE-------RKKYAAK- 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693   105 aneAKAEGNKLFVNGLYEEALSKYAFALELVQElpesielrSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALV 184
Cdd:TIGR00990 130 ---LKEKGNKAYRNKDFNKAIKLYSKAIECKPD--------PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALN 198

                         170
                  ....*....|....*.
gi 30688693   185 RRAEAHEKLEHFEDAV 200
Cdd:TIGR00990 199 RRANAYDGLGKYADAL 214
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 99-201 1.83e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.54  E-value: 1.83e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  99 EKALAEA-NEAKAE---GNKLFVNGLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEETIKECTKALE 174
Cdd:COG3914 102 RRALALNpDNAEALfnlGNLLLALGRLEEALAALRRALALNPDFAEA-------YLNLGEALRRLGRLEEAIAALRRALE 174

                        90       100
                ....*....|....*....|....*..
gi 30688693 175 LNPTYNKALVRRAEAHEKLEHFEDAVT 201
Cdd:COG3914 175 LDPDNAEALNNLGNALQDLGRLEEAIA 201
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 99-200 2.47e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 2.47e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  99 EKALAEANEAKAEGNKLFVNGLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEETIKECTKALELNPT 178
Cdd:COG3914  72 AALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEA-------LFNLGNLLLALGRLEEALAALRRALALNPD 144

                        90       100
                ....*....|....*....|..
gi 30688693 179 YNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG3914 145 FAEAYLNLGEALRRLGRLEEAI 166
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
112-200 3.32e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.01  E-value: 3.32e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 112 GNKLFVNGLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHE 191
Cdd:COG0457  15 GLAYRRLGRYEEAIEDYEKALELDPDDAEA-------LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87


                ....*....
gi 30688693 192 KLEHFEDAV 200
Cdd:COG0457  88 ALGRYEEAL 96
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
99-200 1.98e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 1.98e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  99 EKALA-EANEAKA---EGNKLFVNGLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEETIKECTKALE 174
Cdd:COG0457  32 EKALElDPDDAEAlynLGLAYLRLGRYEEALADYEQALELDPDDAEA-------LNNLGLALQALGRYEEALEDYDKALE 104

                        90       100
                ....*....|....*....|....*.
gi 30688693 175 LNPTYNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG0457 105 LDPDDAEALYNLGLALLELGRYDEAI 130
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
119-200 2.57e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.32  E-value: 2.57e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 119 GLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFED 198
Cdd:COG0457  90 GRYEEALEDYDKALELDPDDAEA-------LYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162


                ..
gi 30688693 199 AV 200
Cdd:COG0457 163 AL 164
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 101-203 5.35e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 5.35e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 101 ALAEANEAKAEGNKLFVNGLYEEALSKYAFALELvqeLPESIELrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYN 180
Cdd:COG5010  50 LAKAFAIESPSDNLYNKLGDFEESLALLEQALQL---DPNNPEL----YYNLALLYSRSGDKDEAKEYYEKALALSPDNP 122

                        90       100
                ....*....|....*....|...
gi 30688693 181 KALVRRAEAHEKLEHFEDAVTGL 203
Cdd:COG5010 123 NAYSNLAALLLSLGQDDEAKAAL 145
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
148-200 1.41e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.31  E-value: 1.41e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 30688693 148 CYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEAL 62
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 112-207 5.42e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.14  E-value: 5.42e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 112 GNKLFVNGLYEEALSKYAFALELvqeLPESIELrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYNKA------LVR 185
Cdd:COG3914 153 GEALRRLGRLEEAIAALRRALEL---DPDNAEA----LNNLGNALQDLGRLEEAIAAYRRALELDPDNADAhsnllfALR 225

                        90       100
                ....*....|....*....|..
gi 30688693 186 RAEAHEKLEHFEDAVTGLVEEP 207
Cdd:COG3914 226 QACDWEVYDRFEELLAALARGP 247
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 112-200 7.80e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 7.80e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 112 GNKLFVNGLYEEALSKYAFALELvqeLPESIELrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHE 191
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALRL---DPDNADA----LLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96


                ....*....
gi 30688693 192 KLEHFEDAV 200
Cdd:COG4235  97 QQGDYAEAI 105
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 148-179 1.38e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.51  E-value: 1.38e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 30688693    148 CYLNRGVCFLKLGKCEETIKECTKALELNPTY 179
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 103-201 1.55e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 1.55e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 103 AEANEAKAEGNKLFVNGLYEEALSKYAfalELVQELPESIELrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYNKA 182
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLE---KALELDPDNPEA----FALLGEILLQLGDLDEAIVLLHEALELDPDEPEA 74

                        90
                ....*....|....*....
gi 30688693 183 LVRRAEAHEKLEHFEDAVT 201
Cdd:COG4783  75 RLNLGLALLKAGDYDEALA 93
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
119-199 1.77e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 1.77e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 119 GLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEETIkECTKALELNPTYNKALVRRAEAHEKLEHFED 198
Cdd:COG3063   6 GDLEEAEEYYEKALELDPDNADA-------LNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDE 77


                .
gi 30688693 199 A 199
Cdd:COG3063  78 A 78
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 105-203 2.12e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 44.39  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  105 ANEAKAEGNKLFVNGLYEEALSKYAFALELVqelPESIELrsicYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALV 184
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLD---PNNAEL----YADRAQANIKLGNFTEAVADANKAIELDPSLAKAYL 74

                         90
                 ....*....|....*....
gi 30688693  185 RRAEAHEKLEHFEDAVTGL 203
Cdd:PLN03088  75 RKGTACMKLEEYQTAKAAL 93
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 114-199 5.51e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 5.51e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 114 KLFVNGLYEEALSKYAfalELVQELPESiELRSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNK---ALVRRAEAH 190
Cdd:COG1729   2 ALLKAGDYDEAIAAFK---AFLKRYPNS-PLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSY 77


                ....*....
gi 30688693 191 EKLEHFEDA 199
Cdd:COG1729  78 LELGDYDKA 86
TPR_1 pfam00515
Tetratricopeptide repeat;
149-179 1.01e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 1.01e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 30688693   149 YLNRGVCFLKLGKCEETIKECTKALELNPTY 179
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 87-200 1.07e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 1.07e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  87 EGEAIVDDGSNKEKALAEANEAKAEGnkLFVNGLYEEALSKYAFALELvqeLPESIELrsicYLNRGVCFLKLGKCEETI 166
Cdd:COG4783  22 EAEALLEKALELDPDNPEAFALLGEI--LLQLGDLDEAIVLLHEALEL---DPDEPEA----RLNLGLALLKAGDYDEAL 92

                        90       100       110
                ....*....|....*....|....*....|....
gi 30688693 167 KECTKALELNPTYNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG4783  93 ALLEKALKLDPEHPEAYLRLARAYRALGRPDEAI 126
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 123-200 1.36e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 1.36e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30688693 123 EALSKYAFALELVQELPESIELRSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAV 200
Cdd:COG2956 121 EQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAI 198
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 99-201 1.45e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 1.45e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  99 EKALAEANEAKAE-----------GNKLFVNGLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEETIK 167
Cdd:COG2956 127 EKAIEVLERLLKLgpenahaycelAELYLEQGDYDEAIEALEKALKLDPDCARA-------LLLLAELYLEQGDYEEAIA 199

                        90       100       110
                ....*....|....*....|....*....|....
gi 30688693 168 ECTKALELNPTYNKALVRRAEAHEKLEHFEDAVT 201
Cdd:COG2956 200 ALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 101-200 1.94e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 1.94e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693 101 ALAEANEAKAEGNKLFVNGLYEEALSKYAFALELVQELPESIELRSICYLNRGVCFLKLGKCEETIKECTKALELNPTYN 180
Cdd:COG5010   9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNP 88

                        90       100
                ....*....|....*....|
gi 30688693 181 KALVRRAEAHEKLEHFEDAV 200
Cdd:COG5010  89 ELYYNLALLYSRSGDKDEAK 108
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 79-201 8.75e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 36.51  E-value: 8.75e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688693  79 EEQIELMSEGEAIVDDGSNKEKALAEANEAKAEGNKLFVNGLYEEALSKYAFALELVQELPESIELRsicylnrgvcFLK 158
Cdd:COG3914  21 AAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALL----------LQA 90

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 30688693 159 LGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAVT 201
Cdd:COG3914  91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALA 133
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 119-189 9.00e-03

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 35.35  E-value: 9.00e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30688693   119 GLYEEALSKYAFALELVQELPESielrsicYLNRGVCFLKLGKCEE---TIKECTKALELNPTYnKALVRRAEA 189
Cdd:TIGR02552  65 KEYEEAIDAYALAAALDPDDPRP-------YFHAAECLLALGEPESalkALDLAIEICGENPEY-SELKERAEA 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH