|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02265 |
PLN02265 |
probable phenylalanyl-tRNA synthetase beta chain |
1-584 |
0e+00 |
|
probable phenylalanyl-tRNA synthetase beta chain
Pssm-ID: 215149 [Multi-domain] Cd Length: 597 Bit Score: 1157.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 1 MPTISVGRDRLFAALGESYTQEKFEELCFSFGIELDDVTTEKAIIRKEKHIDEEADDDEEII----YKIEIPANRPDLLC 76
Cdd:PLN02265 1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHLDEEEDGGADDDeeviYKIDVPANRYDLLC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 77 LEGLAQSLRVFIEKQEIPTYTLADISKDKILQMNVKPETSKIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRS 156
Cdd:PLN02265 81 LEGLARALRVFLGTEPIPTYRLAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 157 LVAIGTHDLDTLQGPFTYEALPPTDINFVPLKQTKSFRADELIEFYKSDMKLKKFLHIIENSPVFPVLYDSKRTVLSLPP 236
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 237 IINGAHSAITLQTKNVFIECTATDLTKAKIVLNTMVTTFSEFCARKFEIEPVEVTYDDGKSYIYPDLAVYDMEVPLSFIT 316
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 317 DSIGVSLKVEQVTSLLTRMQLQAEQakSSDNQCAIKVHVPPSRSDVLHPCDVMEDVAIAYGFNNIPTRKPASI---KPLT 393
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQ--SSDDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMtvgKQQP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 394 LNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNRE-DVNSAVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYPKPI 472
Cdd:PLN02265 399 LNQFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREdDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPI 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 473 KIFEISDVVMLDESKDVGASNRRHLAALYCGATSGFELIHGLVDRIMEVMAIPFLTIHENNvpinekdGYYVKLSQEPEF 552
Cdd:PLN02265 479 KLFEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEIGDNN-------GYYVEPSNEPEY 551
|
570 580 590
....*....|....*....|....*....|..
gi 30698883 553 LPGRQASIIVRGKHIGNFGIVHPEFPSGFEQL 584
Cdd:PLN02265 552 FPGRQASIIYKGKHVGTFGIVHPEVLNNFDIP 583
|
|
| pheT_arch |
TIGR00471 |
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ... |
1-582 |
1.37e-141 |
|
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273096 [Multi-domain] Cd Length: 551 Bit Score: 421.47 E-value: 1.37e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 1 MPTISVGRDRLFaalgESYTQEKFEELCFSF---GIELDDVTTEKAIIrkekhideeadddeeiiyKIEIPANRPDLLCL 77
Cdd:TIGR00471 1 MPTVTVYKDDLE----DLLIGTDRDEILEELpmmGDEIEGFDEESPEI------------------KVEFNPNRPDLLSV 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 78 EGLAQSLRVFIEKQEIPTYTLADISKDKILqmnVKPETSKIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRSL 157
Cdd:TIGR00471 59 EGLARSLRGYLGIEKGLKSYDSKKGDVKLT---VDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 158 VAIGTHDLDTLQGPFTYEALPPTDINFVPLKQTKSFRADELIEFYKsdmKLKKFLHIIENSPVFPVLYDSKRTVLSLPPI 237
Cdd:TIGR00471 136 VAIGIHDLDKVEFPFHYKAVSPNGIKFVPLNSDQEMTPDEILEEHP---KGIRYAHIIEDSDKFPLILDSKDDVLSMPPI 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 238 INGAHSAITLQTKNVFIECTATDLTKAKIVLNTMVTTFSEFCARKFEIEPVEvtYDDGkSYIYPDLAVYDMEVPLSFITD 317
Cdd:TIGR00471 213 INSELTKLTVNTRNLLIDVTGTDKTAVEITLNIACTMFADRGDGRITVVEVE--RPDE-HLGQPNLAPRFMEVSVEYINS 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 318 SIGVSLKVEQVTSLLTRMQLQAEQAKSSdnqcaIKVHVPPSRSDVLHPCDVMEDVAIAYGFNNIPTRKPASI---KPLTL 394
Cdd:TIGR00471 290 LLGLNLSADEIAHSLKKMRLDAVQSDEK-----LKVVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINtigRLKPL 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 395 NELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDvNSAVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYPKPIKI 474
Cdd:TIGR00471 365 NKVSDIIREIMVGLGFQEVIPLTLTSEEVNFKRMRIED-NNDVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKI 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 475 FEISDVVMLDESKdvgASNRRHLAALYCGATSG---FELIHGLVDRIMEVMAIpfltihennvpinekdGYYVKLSQEPE 551
Cdd:TIGR00471 444 FEIGDVVVKDDKS---ETRSRVVTKLAVGITHSeanFNEIKSIVAALARELGI----------------EYEIEESEHPS 504
|
570 580 590
....*....|....*....|....*....|.
gi 30698883 552 FLPGRQASIIVRGKHIGNFGIVHPEFPSGFE 582
Cdd:TIGR00471 505 FIPGRGAKIVFEGKAIGHFGEIHPEVLTNFE 535
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
381-576 |
1.12e-43 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 155.02 E-value: 1.12e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 381 IPTRKP---ASIKPLT-LNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDVNSAVIVGNPRSADFEAMRRALMP 456
Cdd:pfam17759 1 IPSTLPkgpTTGGGLTpEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLLEDDPRRKAVKLANPLSEELSVMRTSLLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 457 GLLKTVGHNNKYP-KPIKIFEISDVVMLDESkDVGASNRRHLAALYCGAT-----------SGFELIHGLVDRIMEVMAI 524
Cdd:pfam17759 81 GLLETLAYNLNRGnPDVRLFEIGRVFLPDEL-EELPREPRRLAGLLTGKRlpeswqgkarpVDFYDLKGIVEALLAALGI 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 30698883 525 pfltihennvpinekDGYYVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPE 576
Cdd:pfam17759 160 ---------------DDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPE 196
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
394-576 |
5.29e-43 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 152.41 E-value: 5.29e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 394 LNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDvnSAVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYP-KPI 472
Cdd:cd00769 2 LQKLERKLRRLLAGLGFQEVITYSLTSPEEAELFDGGLD--EAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnKPL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 473 KIFEISDVVMLDESkdvGASNRRHLAALYCGAT-----------SGFELIHGLVDRIMEVMAIPFltihennvpinekdG 541
Cdd:cd00769 80 RLFEIGRVFLKDED---GPEEEEHLAALLSGNRepeswqgkgrpVDFYDAKGILEALLRALGIIV--------------E 142
|
170 180 190
....*....|....*....|....*....|....*
gi 30698883 542 YYVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPE 576
Cdd:cd00769 143 FELEELDADLFHPGRSAKIYVNGEVIGFIGELHPE 177
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
226-576 |
8.93e-34 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 137.22 E-value: 8.93e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 226 DSKRtVLSLPPIINGAHSAITLQTKNVFIEC----------TA----------------TDLTKAKIVLNTMVTTFSEFC 279
Cdd:COG0072 306 DDEG-PLALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTArrlglhsdasyrfergVDPALTVAALERATQLILEIA 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 280 ARKFEIEPVEVTYDDgksyiYPDLAVydmEVPLSFITDSIGVSLKVEQVTSLLTRMQLQAEQAKSSdnqcaIKVHVPPSR 359
Cdd:COG0072 385 GGEVGPGIVDVYPEP-----PEPKTI---TLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDG-----LTVTVPSWR 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 360 SDVLHPCDVMEDVAIAYGFNNIPTRKP-ASIKPLTLNE---LTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDvns 435
Cdd:COG0072 452 FDIEIEADLIEEVARIYGYDNIPSTLPrAPLAGGGLTEaqrLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRRE--- 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 436 AVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYP-KPIKIFEISDVVMLDESKDvgASNRRHLAALYCGATSG------- 507
Cdd:COG0072 529 AVRLANPISEDLSVMRTSLLPGLLEAAAYNLNRGqKDVRLFEIGRVFLPDEGEE--PREPLHLAGVLTGNREPeswggka 606
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30698883 508 -----FELIhGLVDRIMEVMAIPFLTihennvpinekdgyyVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPE 576
Cdd:COG0072 607 rpvdfFDLK-GDVEALLAALGVPKLE---------------FEAAEHPALHPGRSAEILLGGKVIGFIGELHPK 664
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
119-280 |
1.09e-25 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 103.88 E-value: 1.09e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 119 RPFVVCAVLRGVTFDearYNSFIDLQDKLHQNICRRRSlVAIGTHDLDTLQGPFTYEALPPTDI--NFVPLKQTKSfrAD 196
Cdd:smart00873 1 CPRYLGRVIRGVKNT---RPSPEWLQERLHRAGIRPIN-NVVDITNYVSLETGQPLHAFDLDKIkgKDIPLRRAKE--GE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 197 ELIEFYKSDMKLKKFLHIIENsPVFPVLY-----------DSKRTVLSLPPIINGAHS-AITLQTKNVFIECTA-----T 259
Cdd:smart00873 75 KFETLDGKEYELDEGDLVIAD-DEGPLALagvmggeesevTENTTVIFLEPAIFSPRTiRITARTLNLFTDASGrfergV 153
|
170 180
....*....|....*....|.
gi 30698883 260 DLTKAKIVLNTMVTTFSEFCA 280
Cdd:smart00873 154 DPELVELALDRAAALLLEICG 174
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02265 |
PLN02265 |
probable phenylalanyl-tRNA synthetase beta chain |
1-584 |
0e+00 |
|
probable phenylalanyl-tRNA synthetase beta chain
Pssm-ID: 215149 [Multi-domain] Cd Length: 597 Bit Score: 1157.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 1 MPTISVGRDRLFAALGESYTQEKFEELCFSFGIELDDVTTEKAIIRKEKHIDEEADDDEEII----YKIEIPANRPDLLC 76
Cdd:PLN02265 1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHLDEEEDGGADDDeeviYKIDVPANRYDLLC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 77 LEGLAQSLRVFIEKQEIPTYTLADISKDKILQMNVKPETSKIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRS 156
Cdd:PLN02265 81 LEGLARALRVFLGTEPIPTYRLAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 157 LVAIGTHDLDTLQGPFTYEALPPTDINFVPLKQTKSFRADELIEFYKSDMKLKKFLHIIENSPVFPVLYDSKRTVLSLPP 236
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 237 IINGAHSAITLQTKNVFIECTATDLTKAKIVLNTMVTTFSEFCARKFEIEPVEVTYDDGKSYIYPDLAVYDMEVPLSFIT 316
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 317 DSIGVSLKVEQVTSLLTRMQLQAEQakSSDNQCAIKVHVPPSRSDVLHPCDVMEDVAIAYGFNNIPTRKPASI---KPLT 393
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQ--SSDDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMtvgKQQP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 394 LNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNRE-DVNSAVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYPKPI 472
Cdd:PLN02265 399 LNQFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREdDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPI 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 473 KIFEISDVVMLDESKDVGASNRRHLAALYCGATSGFELIHGLVDRIMEVMAIPFLTIHENNvpinekdGYYVKLSQEPEF 552
Cdd:PLN02265 479 KLFEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEIGDNN-------GYYVEPSNEPEY 551
|
570 580 590
....*....|....*....|....*....|..
gi 30698883 553 LPGRQASIIVRGKHIGNFGIVHPEFPSGFEQL 584
Cdd:PLN02265 552 FPGRQASIIYKGKHVGTFGIVHPEVLNNFDIP 583
|
|
| pheT_arch |
TIGR00471 |
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ... |
1-582 |
1.37e-141 |
|
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273096 [Multi-domain] Cd Length: 551 Bit Score: 421.47 E-value: 1.37e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 1 MPTISVGRDRLFaalgESYTQEKFEELCFSF---GIELDDVTTEKAIIrkekhideeadddeeiiyKIEIPANRPDLLCL 77
Cdd:TIGR00471 1 MPTVTVYKDDLE----DLLIGTDRDEILEELpmmGDEIEGFDEESPEI------------------KVEFNPNRPDLLSV 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 78 EGLAQSLRVFIEKQEIPTYTLADISKDKILqmnVKPETSKIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRSL 157
Cdd:TIGR00471 59 EGLARSLRGYLGIEKGLKSYDSKKGDVKLT---VDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 158 VAIGTHDLDTLQGPFTYEALPPTDINFVPLKQTKSFRADELIEFYKsdmKLKKFLHIIENSPVFPVLYDSKRTVLSLPPI 237
Cdd:TIGR00471 136 VAIGIHDLDKVEFPFHYKAVSPNGIKFVPLNSDQEMTPDEILEEHP---KGIRYAHIIEDSDKFPLILDSKDDVLSMPPI 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 238 INGAHSAITLQTKNVFIECTATDLTKAKIVLNTMVTTFSEFCARKFEIEPVEvtYDDGkSYIYPDLAVYDMEVPLSFITD 317
Cdd:TIGR00471 213 INSELTKLTVNTRNLLIDVTGTDKTAVEITLNIACTMFADRGDGRITVVEVE--RPDE-HLGQPNLAPRFMEVSVEYINS 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 318 SIGVSLKVEQVTSLLTRMQLQAEQAKSSdnqcaIKVHVPPSRSDVLHPCDVMEDVAIAYGFNNIPTRKPASI---KPLTL 394
Cdd:TIGR00471 290 LLGLNLSADEIAHSLKKMRLDAVQSDEK-----LKVVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINtigRLKPL 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 395 NELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDvNSAVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYPKPIKI 474
Cdd:TIGR00471 365 NKVSDIIREIMVGLGFQEVIPLTLTSEEVNFKRMRIED-NNDVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKI 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 475 FEISDVVMLDESKdvgASNRRHLAALYCGATSG---FELIHGLVDRIMEVMAIpfltihennvpinekdGYYVKLSQEPE 551
Cdd:TIGR00471 444 FEIGDVVVKDDKS---ETRSRVVTKLAVGITHSeanFNEIKSIVAALARELGI----------------EYEIEESEHPS 504
|
570 580 590
....*....|....*....|....*....|.
gi 30698883 552 FLPGRQASIIVRGKHIGNFGIVHPEFPSGFE 582
Cdd:TIGR00471 505 FIPGRGAKIVFEGKAIGHFGEIHPEVLTNFE 535
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
381-576 |
1.12e-43 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 155.02 E-value: 1.12e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 381 IPTRKP---ASIKPLT-LNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDVNSAVIVGNPRSADFEAMRRALMP 456
Cdd:pfam17759 1 IPSTLPkgpTTGGGLTpEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLLEDDPRRKAVKLANPLSEELSVMRTSLLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 457 GLLKTVGHNNKYP-KPIKIFEISDVVMLDESkDVGASNRRHLAALYCGAT-----------SGFELIHGLVDRIMEVMAI 524
Cdd:pfam17759 81 GLLETLAYNLNRGnPDVRLFEIGRVFLPDEL-EELPREPRRLAGLLTGKRlpeswqgkarpVDFYDLKGIVEALLAALGI 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 30698883 525 pfltihennvpinekDGYYVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPE 576
Cdd:pfam17759 160 ---------------DDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPE 196
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
394-576 |
5.29e-43 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 152.41 E-value: 5.29e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 394 LNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDvnSAVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYP-KPI 472
Cdd:cd00769 2 LQKLERKLRRLLAGLGFQEVITYSLTSPEEAELFDGGLD--EAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnKPL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 473 KIFEISDVVMLDESkdvGASNRRHLAALYCGAT-----------SGFELIHGLVDRIMEVMAIPFltihennvpinekdG 541
Cdd:cd00769 80 RLFEIGRVFLKDED---GPEEEEHLAALLSGNRepeswqgkgrpVDFYDAKGILEALLRALGIIV--------------E 142
|
170 180 190
....*....|....*....|....*....|....*
gi 30698883 542 YYVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPE 576
Cdd:cd00769 143 FELEELDADLFHPGRSAKIYVNGEVIGFIGELHPE 177
|
|
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
228-577 |
1.15e-37 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 148.78 E-value: 1.15e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 228 KRTVLSLPPIINGAHSAITLQTKNVFIEC----------TATDL---TKA----------KIVLNTMvttfsEFCARKF- 283
Cdd:PRK00629 306 DKKPLALAGVMGGEDSEVTENTTNVLLESayfdpvsirkTARRLglrTDAsyrfergvdpALTLLAL-----ERATALIl 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 284 EI---EPVEVTYDDgksYIYPDLAVYDMevPLSFITDSIGVSLKVEQVTSLLTRMQLQAEQakssDNQCAIKVHVPPSRS 360
Cdd:PRK00629 381 ELgggEVVEGVVDV---YPLPKEPTITL--RLERINRLLGTEISDEEIVDILKRLGFEVTE----VDGDGLTVTVPSWRF 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 361 DVLHPCDVMEDVAIAYGFNNIPTRKPAS---IKPLT-LNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDVnsa 436
Cdd:PRK00629 452 DIEIEEDLVEEVARIYGYDNIPSTPPVAaltMGGLTeAQRLLRRLRRALAALGYQEVITYSFVSPEDAKLFGLNPEP--- 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 437 VIVGNPRSADFEAMRRALMPGLLKTVGHNNKY-PKPIKIFEISDVVmldESKDVGASNRRHLAALYCGATS--------- 506
Cdd:PRK00629 529 LLLLNPISEELSVMRTSLLPGLLEAVAYNLNRgNKDVALFEIGRVF---LPDGDLPREPEHLAGVLTGNRVeeswggkrp 605
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30698883 507 -GFELIHGLVDRIMEVMAIPFLTihennvpinekdgyYVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPEF 577
Cdd:PRK00629 606 vDFFDLKGDVEALLEALGLPEVE--------------FVAEFEAAALHPGRSAEIYLDGKVIGFIGELHPKV 663
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
226-576 |
8.93e-34 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 137.22 E-value: 8.93e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 226 DSKRtVLSLPPIINGAHSAITLQTKNVFIEC----------TA----------------TDLTKAKIVLNTMVTTFSEFC 279
Cdd:COG0072 306 DDEG-PLALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTArrlglhsdasyrfergVDPALTVAALERATQLILEIA 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 280 ARKFEIEPVEVTYDDgksyiYPDLAVydmEVPLSFITDSIGVSLKVEQVTSLLTRMQLQAEQAKSSdnqcaIKVHVPPSR 359
Cdd:COG0072 385 GGEVGPGIVDVYPEP-----PEPKTI---TLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDG-----LTVTVPSWR 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 360 SDVLHPCDVMEDVAIAYGFNNIPTRKP-ASIKPLTLNE---LTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDvns 435
Cdd:COG0072 452 FDIEIEADLIEEVARIYGYDNIPSTLPrAPLAGGGLTEaqrLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRRE--- 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 436 AVIVGNPRSADFEAMRRALMPGLLKTVGHNNKYP-KPIKIFEISDVVMLDESKDvgASNRRHLAALYCGATSG------- 507
Cdd:COG0072 529 AVRLANPISEDLSVMRTSLLPGLLEAAAYNLNRGqKDVRLFEIGRVFLPDEGEE--PREPLHLAGVLTGNREPeswggka 606
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30698883 508 -----FELIhGLVDRIMEVMAIPFLTihennvpinekdgyyVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPE 576
Cdd:COG0072 607 rpvdfFDLK-GDVEALLAALGVPKLE---------------FEAAEHPALHPGRSAEILLGGKVIGFIGELHPK 664
|
|
| PhetRS_B1 |
pfam18262 |
Phe-tRNA synthetase beta subunit B1 domain; This is the N-terminal domain found in human ... |
1-90 |
4.91e-29 |
|
Phe-tRNA synthetase beta subunit B1 domain; This is the N-terminal domain found in human cytosolic phenylalanyl tRNA synthetase beta subunit.
Pssm-ID: 408077 Cd Length: 83 Bit Score: 110.20 E-value: 4.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 1 MPTISVGRDRLFAALGESYTQEKFEELCFSFGIELDDVTTEKAiirkekhIDEEADDDEEIIYKIEIPANRPDLLCLEGL 80
Cdd:pfam18262 1 MPTISVKKVRLFKVLGRVYTEEEFSDLCFEFGLELDEITSEEN-------QLKTSWRSEEVVYKIDIPANRYDLLCVEGL 73
|
90
....*....|
gi 30698883 81 AQSLRVFIEK 90
Cdd:pfam18262 74 ATALLIFKGK 83
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
119-280 |
1.09e-25 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 103.88 E-value: 1.09e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 119 RPFVVCAVLRGVTFDearYNSFIDLQDKLHQNICRRRSlVAIGTHDLDTLQGPFTYEALPPTDI--NFVPLKQTKSfrAD 196
Cdd:smart00873 1 CPRYLGRVIRGVKNT---RPSPEWLQERLHRAGIRPIN-NVVDITNYVSLETGQPLHAFDLDKIkgKDIPLRRAKE--GE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 197 ELIEFYKSDMKLKKFLHIIENsPVFPVLY-----------DSKRTVLSLPPIINGAHS-AITLQTKNVFIECTA-----T 259
Cdd:smart00873 75 KFETLDGKEYELDEGDLVIAD-DEGPLALagvmggeesevTENTTVIFLEPAIFSPRTiRITARTLNLFTDASGrfergV 153
|
170 180
....*....|....*....|.
gi 30698883 260 DLTKAKIVLNTMVTTFSEFCA 280
Cdd:smart00873 154 DPELVELALDRAAALLLEICG 174
|
|
| B5 |
pfam03484 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
308-378 |
3.76e-17 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 460942 [Multi-domain] Cd Length: 67 Bit Score: 75.89 E-value: 3.76e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30698883 308 MEVPLSFITDSIGVSLKVEQVTSLLTRMQLQAEqaksSDNQCAIKVHVPPSRSDVLHPCDVMEDVAIAYGF 378
Cdd:pfam03484 1 ITLRLDRINRLLGIDLSAEEIVEILERLGFEVE----EEDGDTLTVTVPSYRPDILHEADLIEEVARIYGY 67
|
|
| B5 |
smart00874 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
308-378 |
3.13e-15 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 197942 [Multi-domain] Cd Length: 68 Bit Score: 70.22 E-value: 3.13e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30698883 308 MEVPLSFITDSIGVSLKVEQVTSLLTRMQLQAEQAKSSdnqcaIKVHVPPSRSDVLHPCDVMEDVAIAYGF 378
Cdd:smart00874 3 ITLRLERINRLLGLEILAEEIEEILKRLGFEVEVSGDT-----LEVTVPSYRFDILIEADLIEEVARIYGY 68
|
|
| B3_4 |
pfam03483 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
118-260 |
2.60e-14 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 427327 [Multi-domain] Cd Length: 174 Bit Score: 71.04 E-value: 2.60e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30698883 118 IRPFVVCAVLRGVTFDEAR---------------YNSFIDLQDKLHQNICRrrslvAIGTHDLDTLQGPFTyealpptdi 182
Cdd:pfam03483 1 ACPRYFGRVIRGVKKNRPSpewlqrrlrragirpINNVVDITNYVMLELGQ-----PLHAFDLDKIAGDIV--------- 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30698883 183 nfVPLKQTKsfraDELIEFYKSDMKLKkflhiiensPVFPVLYDSKRtVLSLPPIINGAHSAITLQTKNVFIECTATD 260
Cdd:pfam03483 67 --VRLAKGG----EKFTTLDGKERELD---------PGDLVIADDDG-PVALAGIMGGEESEVTEDTTNIFLESAGFD 128
|
|
| |
