NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|30680874|ref|NP_850772|]
View 

TLC ATP/ADP transporter [Arabidopsis thaliana]

Protein Classification

NTP/NDP exchange transporter; ATP translocase( domain architecture ID 1904962)

NTP/NDP exchange transporter is a nucleotide transporter that may catalyze ATP/ADP exchange, or GTP, CTP, ATP, and UTP uptake through a proton symport mechanism; belongs to the Major Facilitator Superfamily (MFS)| ATP translocase catalyzes the highly specific transport of ATP across a membrane in an exchange mode with ADP; also contains a dystroglycan-type cadherin-like domain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TlcC super family cl43811
ATP/ADP translocase [Energy production and conversion];
11-489 2.59e-59

ATP/ADP translocase [Energy production and conversion];


The actual alignment was detected with superfamily member COG3202:

Pssm-ID: 442435  Cd Length: 430  Bit Score: 202.02  E-value: 2.59e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874  11 ISTIVTVHPHELPALLHSSSCFFFILSAYFVVLPLRDEGAIS-LGLSKLPGLFVGSLFLTLIAAPLSTFIFSlpNLSKSK 89
Cdd:COG3202   8 LARLFPIRPGELKKFLLLFLLFFLILFAYYILRPIRDALFLTgLGAEVLPWLKTGTAPVALLAVPLYSKLVN--RLSRRR 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874  90 ALVIIHRFFSLSLVLCFLLWMASPTESNSKdaveaasgltndganaatgwdnhgWFYISvrvgFFLWVALLNLVAISSTW 169
Cdd:COG3202  86 LFYVVYLFFLLFLLLFAFLLYPNRDAIIRK------------------------WVGRL----FYVWVELFNLFVVSLFW 137

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 170 ARIIDVMDIQSGARLFGFVGAGATLGQLFGSVFAAA-TAWMGP-YLLLFAALLMEFAAQSSKGITNDISQSSEElsplrg 247
Cdd:COG3202 138 SFANDIFNTREAKRLFGLIGAGGTLGGILGGFLTSLlAKFLGLaNLLLVAAVLLLIALLLLRYLNRRVPRLPDA------ 211

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 248 tdndhqrERKQEATSPKVGSpkvaspkspisttrpqfwaILDGMRLILASPYLLLVSLFLWLGAVISSFFYFQKVNIIAT 327
Cdd:COG3202 212 -------AAKATKKKKIKGG-------------------LLEGLKLILKSPYLLLIALLVLLYNIVITLVEFQWKDIVKE 265

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 328 TIKSSIGRRRLFAQINSFVAVFILIGQLTLTGRILTVAGVTVAISASPFVALGNLVAIAIWPTWVTVAVSETLRKVTTYV 407
Cdd:COG3202 266 AYPDPAELAAFFGFFDLIVNLLTLLLQLFVTSRLLRRLGVGVALLITPVIILVGGLLFFLFPALAVGAIQNVLSRALKYS 345

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 408 VTRPGRELLFTVVSQDEKYKAKVCIDVIVQRLGDAAAAGLFEVLTIALGGQTSTASLYALPVCLIWIVTAFFLGRRQEQL 487
Cdd:COG3202 346 LFDPTREMLYIPLDRELKYKGKAFIDTVVYRLGKSLGGWILIGLLSLLGLSAPYLAVIFIVLALLWILAAFKLGREYKRL 425


                ..
gi 30680874 488 AK 489
Cdd:COG3202 426 LK 427
 
Name Accession Description Interval E-value
TlcC COG3202
ATP/ADP translocase [Energy production and conversion];
11-489 2.59e-59

ATP/ADP translocase [Energy production and conversion];


Pssm-ID: 442435  Cd Length: 430  Bit Score: 202.02  E-value: 2.59e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874  11 ISTIVTVHPHELPALLHSSSCFFFILSAYFVVLPLRDEGAIS-LGLSKLPGLFVGSLFLTLIAAPLSTFIFSlpNLSKSK 89
Cdd:COG3202   8 LARLFPIRPGELKKFLLLFLLFFLILFAYYILRPIRDALFLTgLGAEVLPWLKTGTAPVALLAVPLYSKLVN--RLSRRR 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874  90 ALVIIHRFFSLSLVLCFLLWMASPTESNSKdaveaasgltndganaatgwdnhgWFYISvrvgFFLWVALLNLVAISSTW 169
Cdd:COG3202  86 LFYVVYLFFLLFLLLFAFLLYPNRDAIIRK------------------------WVGRL----FYVWVELFNLFVVSLFW 137

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 170 ARIIDVMDIQSGARLFGFVGAGATLGQLFGSVFAAA-TAWMGP-YLLLFAALLMEFAAQSSKGITNDISQSSEElsplrg 247
Cdd:COG3202 138 SFANDIFNTREAKRLFGLIGAGGTLGGILGGFLTSLlAKFLGLaNLLLVAAVLLLIALLLLRYLNRRVPRLPDA------ 211

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 248 tdndhqrERKQEATSPKVGSpkvaspkspisttrpqfwaILDGMRLILASPYLLLVSLFLWLGAVISSFFYFQKVNIIAT 327
Cdd:COG3202 212 -------AAKATKKKKIKGG-------------------LLEGLKLILKSPYLLLIALLVLLYNIVITLVEFQWKDIVKE 265

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 328 TIKSSIGRRRLFAQINSFVAVFILIGQLTLTGRILTVAGVTVAISASPFVALGNLVAIAIWPTWVTVAVSETLRKVTTYV 407
Cdd:COG3202 266 AYPDPAELAAFFGFFDLIVNLLTLLLQLFVTSRLLRRLGVGVALLITPVIILVGGLLFFLFPALAVGAIQNVLSRALKYS 345

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 408 VTRPGRELLFTVVSQDEKYKAKVCIDVIVQRLGDAAAAGLFEVLTIALGGQTSTASLYALPVCLIWIVTAFFLGRRQEQL 487
Cdd:COG3202 346 LFDPTREMLYIPLDRELKYKGKAFIDTVVYRLGKSLGGWILIGLLSLLGLSAPYLAVIFIVLALLWILAAFKLGREYKRL 425


                ..
gi 30680874 488 AK 489
Cdd:COG3202 426 LK 427
 
Name Accession Description Interval E-value
TlcC COG3202
ATP/ADP translocase [Energy production and conversion];
11-489 2.59e-59

ATP/ADP translocase [Energy production and conversion];


Pssm-ID: 442435  Cd Length: 430  Bit Score: 202.02  E-value: 2.59e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874  11 ISTIVTVHPHELPALLHSSSCFFFILSAYFVVLPLRDEGAIS-LGLSKLPGLFVGSLFLTLIAAPLSTFIFSlpNLSKSK 89
Cdd:COG3202   8 LARLFPIRPGELKKFLLLFLLFFLILFAYYILRPIRDALFLTgLGAEVLPWLKTGTAPVALLAVPLYSKLVN--RLSRRR 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874  90 ALVIIHRFFSLSLVLCFLLWMASPTESNSKdaveaasgltndganaatgwdnhgWFYISvrvgFFLWVALLNLVAISSTW 169
Cdd:COG3202  86 LFYVVYLFFLLFLLLFAFLLYPNRDAIIRK------------------------WVGRL----FYVWVELFNLFVVSLFW 137

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 170 ARIIDVMDIQSGARLFGFVGAGATLGQLFGSVFAAA-TAWMGP-YLLLFAALLMEFAAQSSKGITNDISQSSEElsplrg 247
Cdd:COG3202 138 SFANDIFNTREAKRLFGLIGAGGTLGGILGGFLTSLlAKFLGLaNLLLVAAVLLLIALLLLRYLNRRVPRLPDA------ 211

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 248 tdndhqrERKQEATSPKVGSpkvaspkspisttrpqfwaILDGMRLILASPYLLLVSLFLWLGAVISSFFYFQKVNIIAT 327
Cdd:COG3202 212 -------AAKATKKKKIKGG-------------------LLEGLKLILKSPYLLLIALLVLLYNIVITLVEFQWKDIVKE 265

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 328 TIKSSIGRRRLFAQINSFVAVFILIGQLTLTGRILTVAGVTVAISASPFVALGNLVAIAIWPTWVTVAVSETLRKVTTYV 407
Cdd:COG3202 266 AYPDPAELAAFFGFFDLIVNLLTLLLQLFVTSRLLRRLGVGVALLITPVIILVGGLLFFLFPALAVGAIQNVLSRALKYS 345

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30680874 408 VTRPGRELLFTVVSQDEKYKAKVCIDVIVQRLGDAAAAGLFEVLTIALGGQTSTASLYALPVCLIWIVTAFFLGRRQEQL 487
Cdd:COG3202 346 LFDPTREMLYIPLDRELKYKGKAFIDTVVYRLGKSLGGWILIGLLSLLGLSAPYLAVIFIVLALLWILAAFKLGREYKRL 425


                ..
gi 30680874 488 AK 489
Cdd:COG3202 426 LK 427
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH