enkurin domain-containing protein 1 [Mus musculus]
enkurin domain-containing protein( domain architecture ID 10620564)
enkurin domain-containing protein similar to human enkurin, an adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel
List of domain hits
Name | Accession | Description | Interval | E-value | |||
Enkurin | pfam13864 | Calmodulin-binding; This is a family of apparent calmodulin-binding proteins found at high ... |
243-337 | 1.44e-20 | |||
Calmodulin-binding; This is a family of apparent calmodulin-binding proteins found at high levels in the testis and vomeronasal organ and at lower levels in certain other tissues. Enkurin is a scaffold protein that binds PI3 kinase to sperm transient receptor potential (canonical) (TRPC) channels. The mammalian transient receptor potential (canonical) channels are the primary candidates for the Ca(2+) entry pathway activated by the hormones, growth factors, and neurotransmitters that exert their effect through activation of PLC. Calmodulin binds to the C-terminus of all TRPC channels, and dissociation of calmodulin from TRPC4 results in profound activation of the channel. : Pssm-ID: 464004 [Multi-domain] Cd Length: 92 Bit Score: 84.93 E-value: 1.44e-20
|
|||||||
Name | Accession | Description | Interval | E-value | |||
Enkurin | pfam13864 | Calmodulin-binding; This is a family of apparent calmodulin-binding proteins found at high ... |
243-337 | 1.44e-20 | |||
Calmodulin-binding; This is a family of apparent calmodulin-binding proteins found at high levels in the testis and vomeronasal organ and at lower levels in certain other tissues. Enkurin is a scaffold protein that binds PI3 kinase to sperm transient receptor potential (canonical) (TRPC) channels. The mammalian transient receptor potential (canonical) channels are the primary candidates for the Ca(2+) entry pathway activated by the hormones, growth factors, and neurotransmitters that exert their effect through activation of PLC. Calmodulin binds to the C-terminus of all TRPC channels, and dissociation of calmodulin from TRPC4 results in profound activation of the channel. Pssm-ID: 464004 [Multi-domain] Cd Length: 92 Bit Score: 84.93 E-value: 1.44e-20
|
|||||||
Name | Accession | Description | Interval | E-value | |||
Enkurin | pfam13864 | Calmodulin-binding; This is a family of apparent calmodulin-binding proteins found at high ... |
243-337 | 1.44e-20 | |||
Calmodulin-binding; This is a family of apparent calmodulin-binding proteins found at high levels in the testis and vomeronasal organ and at lower levels in certain other tissues. Enkurin is a scaffold protein that binds PI3 kinase to sperm transient receptor potential (canonical) (TRPC) channels. The mammalian transient receptor potential (canonical) channels are the primary candidates for the Ca(2+) entry pathway activated by the hormones, growth factors, and neurotransmitters that exert their effect through activation of PLC. Calmodulin binds to the C-terminus of all TRPC channels, and dissociation of calmodulin from TRPC4 results in profound activation of the channel. Pssm-ID: 464004 [Multi-domain] Cd Length: 92 Bit Score: 84.93 E-value: 1.44e-20
|
|||||||
Blast search parameters | ||||
|