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Conserved domains on  [gi|38348202|ref|NP_940845|]
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neuritin-like protein isoform 1 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NRN1 super family cl20929
Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein ...
 42-117 3.27e-31

Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.


The actual alignment was detected with superfamily member pfam15056:

Pssm-ID: 434424  Cd Length: 89  Bit Score: 107.86  E-value: 3.27e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348202    42 CDTIYQGFAECLIRLGDSMGR---------GGELETICRSWNDFHACASQVLSGCPEEAAAVWESLQQEARQAPRPNNLH 112
Cdd:pfam15056   1 CDAIYKGFSDCLLKLGDSMANypqelddeeTQNLDTICKYWDDFHTCALTALSDCQEEAADVWESLRQESKKLQFQGSLF 80


                  ....*
gi 38348202   113 TLCGA 117
Cdd:pfam15056  81 DLCSS 85
 
Name Accession Description Interval E-value
NRN1 pfam15056
Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein ...
 42-117 3.27e-31

Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.


Pssm-ID: 434424  Cd Length: 89  Bit Score: 107.86  E-value: 3.27e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348202    42 CDTIYQGFAECLIRLGDSMGR---------GGELETICRSWNDFHACASQVLSGCPEEAAAVWESLQQEARQAPRPNNLH 112
Cdd:pfam15056   1 CDAIYKGFSDCLLKLGDSMANypqelddeeTQNLDTICKYWDDFHTCALTALSDCQEEAADVWESLRQESKKLQFQGSLF 80


                  ....*
gi 38348202   113 TLCGA 117
Cdd:pfam15056  81 DLCSS 85
 
Name Accession Description Interval E-value
NRN1 pfam15056
Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein ...
 42-117 3.27e-31

Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.


Pssm-ID: 434424  Cd Length: 89  Bit Score: 107.86  E-value: 3.27e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348202    42 CDTIYQGFAECLIRLGDSMGR---------GGELETICRSWNDFHACASQVLSGCPEEAAAVWESLQQEARQAPRPNNLH 112
Cdd:pfam15056   1 CDAIYKGFSDCLLKLGDSMANypqelddeeTQNLDTICKYWDDFHTCALTALSDCQEEAADVWESLRQESKKLQFQGSLF 80


                  ....*
gi 38348202   113 TLCGA 117
Cdd:pfam15056  81 DLCSS 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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