|
Name |
Accession |
Description |
Interval |
E-value |
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
8-366 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 628.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 8 VNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFSAVP 87
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 88 LNLIGLKagRCADYVVTGAWSAKAAEEAKKFGT-VNIVHPKL-GSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFI 165
Cdd:cd00611 81 LNLLGDK--GTADYVVTGAWSAKAAKEAKRYGGvVVIVAAKEeGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 166 PDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTPPC 245
Cdd:cd00611 159 PDTGGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 246 FSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIgnskGDEALEKRFLDKAV 325
Cdd:cd00611 239 FAIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRL----GKEELEKEFLKEAE 314
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 61889115 326 ELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLE 366
Cdd:cd00611 315 AAGMIGLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
15-368 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 610.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 15 AKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFSAVPLNLigLK 94
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNL--LA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 95 AGRCADYVVTGAWSAKAAEEAKKFGTVNIV-HPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFIPDVKGAVL 173
Cdd:TIGR01364 79 EGKVADYIVTGAWSKKAAKEAKKYGVVNVVaSGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 174 VCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTPPCFSIYVMDM 253
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 254 VLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNskgdEALEKRFLDKAVELNMISLK 333
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGN----EELEKRFLKEAEERGLVSLK 314
|
330 340 350
....*....|....*....|....*....|....*
gi 61889115 334 GHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMH 368
Cdd:TIGR01364 315 GHRSVGGMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
5-364 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 582.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 5 KQVVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFS 84
Cdd:PRK05355 2 MRVYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQFA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 85 AVPLNLigLKAGRCADYVVTGAWSAKAAEEAKKFGTVNIVHP-KLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFD 163
Cdd:PRK05355 82 MVPMNL--LGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASsEDDGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 164 FIPDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTP 243
Cdd:PRK05355 160 ELPDTGDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 244 PCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnskGDEALEKRFLDK 323
Cdd:PRK05355 240 PTFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSS-DFYRNPVAPEDRSRMNVPFTL----ADEELDKKFLAE 314
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 61889115 324 AVELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNF 364
Cdd:PRK05355 315 AKAAGLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEF 355
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
5-368 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 563.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 5 KQVVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFS 84
Cdd:COG1932 1 MRVYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 85 AVPLNLIGlkAGRCADYVVTGAWSAKAAEEAKKFGTVNIVH-PKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFD 163
Cdd:COG1932 81 MVPMNLLR--GGKKADYLVTGEWSKKAIKEAKKYGEVNVVAsSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFH 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 164 FIPDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTP 243
Cdd:COG1932 159 ELPDVGDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 244 PCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnskGDEALEKRFLDK 323
Cdd:COG1932 239 PTFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDAS-DFYTNPVDPEDRSRMNVTFDL----ADEELDAAFLAE 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 61889115 324 AVELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMH 368
Cdd:COG1932 314 AKAAGLVGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
7-357 |
1.45e-83 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 258.33 E-value: 1.45e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 7 VVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISvlEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQgGGTGQFSAV 86
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTS-GTTEAINLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 87 PLNLI-GLKAGRCADYVVTGAWSAK-AAEEAKKFGTVNIVHPKL---GSYTkiPDPSTWNLNPDASYVYFCANETVHGVE 161
Cdd:pfam00266 78 ALSLGrSLKPGDEIVITEMEHHANLvPWQELAKRTGARVRVLPLdedGLLD--LDELEKLITPKTKLVAITHVSNVTGTI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 162 FDfIPDV------KGAVLVCDMSSNFLSRPVDVSKFGV--IFAGAQKNVGSAGVTVVIVRDDLLGFA--------LRECP 225
Cdd:pfam00266 156 QP-VPEIgklahqYGALVLVDAAQAIGHRPIDVQKLGVdfLAFSGHKLYGPTGIGVLYGRRDLLEKMppllggggMIETV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 226 SvLDYKVQAGNNSLYN--TPPCFSIYVMDMVLEWIkNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERqNRSRMNI 303
Cdd:pfam00266 235 S-LQESTFADAPWKFEagTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPER-RASIISF 311
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 61889115 304 PFRIGNSkgdeALEKRFLDK-AVELN------MISLKGHRSVGGIRASLYNAVTTEDVEKL 357
Cdd:pfam00266 312 NFKGVHP----HDVATLLDEsGIAVRsghhcaQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
8-366 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 628.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 8 VNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFSAVP 87
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 88 LNLIGLKagRCADYVVTGAWSAKAAEEAKKFGT-VNIVHPKL-GSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFI 165
Cdd:cd00611 81 LNLLGDK--GTADYVVTGAWSAKAAKEAKRYGGvVVIVAAKEeGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 166 PDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTPPC 245
Cdd:cd00611 159 PDTGGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 246 FSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIgnskGDEALEKRFLDKAV 325
Cdd:cd00611 239 FAIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRL----GKEELEKEFLKEAE 314
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 61889115 326 ELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLE 366
Cdd:cd00611 315 AAGMIGLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
15-368 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 610.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 15 AKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFSAVPLNLigLK 94
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNL--LA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 95 AGRCADYVVTGAWSAKAAEEAKKFGTVNIV-HPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFIPDVKGAVL 173
Cdd:TIGR01364 79 EGKVADYIVTGAWSKKAAKEAKKYGVVNVVaSGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 174 VCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTPPCFSIYVMDM 253
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 254 VLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNskgdEALEKRFLDKAVELNMISLK 333
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGN----EELEKRFLKEAEERGLVSLK 314
|
330 340 350
....*....|....*....|....*....|....*
gi 61889115 334 GHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMH 368
Cdd:TIGR01364 315 GHRSVGGMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
5-364 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 582.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 5 KQVVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFS 84
Cdd:PRK05355 2 MRVYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQFA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 85 AVPLNLigLKAGRCADYVVTGAWSAKAAEEAKKFGTVNIVHP-KLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFD 163
Cdd:PRK05355 82 MVPMNL--LGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASsEDDGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 164 FIPDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTP 243
Cdd:PRK05355 160 ELPDTGDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 244 PCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnskGDEALEKRFLDK 323
Cdd:PRK05355 240 PTFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSS-DFYRNPVAPEDRSRMNVPFTL----ADEELDKKFLAE 314
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 61889115 324 AVELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNF 364
Cdd:PRK05355 315 AKAAGLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEF 355
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
5-368 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 563.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 5 KQVVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFS 84
Cdd:COG1932 1 MRVYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 85 AVPLNLIGlkAGRCADYVVTGAWSAKAAEEAKKFGTVNIVH-PKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFD 163
Cdd:COG1932 81 MVPMNLLR--GGKKADYLVTGEWSKKAIKEAKKYGEVNVVAsSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFH 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 164 FIPDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTP 243
Cdd:COG1932 159 ELPDVGDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 244 PCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnskGDEALEKRFLDK 323
Cdd:COG1932 239 PTFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDAS-DFYTNPVDPEDRSRMNVTFDL----ADEELDAAFLAE 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 61889115 324 AVELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMH 368
Cdd:COG1932 314 AKAAGLVGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PLN02452 |
PLN02452 |
phosphoserine transaminase |
2-369 |
0e+00 |
|
phosphoserine transaminase
Pssm-ID: 178071 Cd Length: 365 Bit Score: 513.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 2 EATKQVVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTG 81
Cdd:PLN02452 3 GSQGRVFNFSAGPATLPANVLAKAQAELYNWEGSGMSVMEMSHRGKEFLSIIQKAEADLRELLDIPDNYEVLFLQGGAST 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 82 QFSAVPLNLIglKAGRCADYVVTGAWSAKAAEEAKKFGTVNIVHP-KLGSYTKIPDPSTWNLNPDASYVYFCANETVHGV 160
Cdd:PLN02452 83 QFAAIPLNLC--KPGDKADFVVTGSWSKKAAKEAKKYCKTNVIASgKDEKYTKIPSVSEWELTPDAKFVHICANETIHGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 161 EFDFIPDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLY 240
Cdd:PLN02452 161 EFKDYPDVGNVPLVADMSSNFLSKPVDVSKYGVIYAGAQKNVGPSGVTIVIIRKDLIGNARPITPGMLDYKIHAENDSLY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 241 NTPPCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNSkgdeALEKRF 320
Cdd:PLN02452 241 NTPPCFGIYMCGLVFEDLLAQGGLKAMEKRNIRKADLLYDAIDESNGFYVCPVEKSVRSLMNVPFTLGGS----ELEAEF 316
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 61889115 321 LDKAVELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMHQ 369
Cdd:PLN02452 317 VKEAAKAGMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA 365
|
|
| PRK12462 |
PRK12462 |
phosphoserine aminotransferase; Provisional |
8-364 |
6.59e-127 |
|
phosphoserine aminotransferase; Provisional
Pssm-ID: 183540 Cd Length: 364 Bit Score: 369.14 E-value: 6.59e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 8 VNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFSAVP 87
Cdd:PRK12462 6 LNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAEADLRDLLGIPDEYGVVFLQGGSSLQFSMIP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 88 LNLIgLKAGRCADYVVTGAWSAKAAEEAKKFGTVNIV-HPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFIP 166
Cdd:PRK12462 86 MNFS-RPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVwDGAASGYRTLPSLAELDWDARAPFRHYVSNETVEGLQFPDAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 167 DVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLDYKVQAGNNSLYNTPPCF 246
Cdd:PRK12462 165 GLPDSPLIADMSSDFMSRPFDVEAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNTPPVF 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 247 SIYVMDMVLEWIKNN-GGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIgnskGDEALEKRFLDKAV 325
Cdd:PRK12462 245 AIYVMALVLRWIRDEiGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRF----RQPRLDTLFKEQST 320
|
330 340 350
....*....|....*....|....*....|....*....
gi 61889115 326 ELNMISLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNF 364
Cdd:PRK12462 321 EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDF 359
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
7-357 |
1.45e-83 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 258.33 E-value: 1.45e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 7 VVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISvlEMSHRSPDFAKIISNTENLVRELLVVPNNYKVIFVQgGGTGQFSAV 86
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTS-GTTEAINLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 87 PLNLI-GLKAGRCADYVVTGAWSAK-AAEEAKKFGTVNIVHPKL---GSYTkiPDPSTWNLNPDASYVYFCANETVHGVE 161
Cdd:pfam00266 78 ALSLGrSLKPGDEIVITEMEHHANLvPWQELAKRTGARVRVLPLdedGLLD--LDELEKLITPKTKLVAITHVSNVTGTI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 162 FDfIPDV------KGAVLVCDMSSNFLSRPVDVSKFGV--IFAGAQKNVGSAGVTVVIVRDDLLGFA--------LRECP 225
Cdd:pfam00266 156 QP-VPEIgklahqYGALVLVDAAQAIGHRPIDVQKLGVdfLAFSGHKLYGPTGIGVLYGRRDLLEKMppllggggMIETV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 226 SvLDYKVQAGNNSLYN--TPPCFSIYVMDMVLEWIkNNGGAAAMEKLSSVKSQMIYEIIDNSQGFYVCPVERqNRSRMNI 303
Cdd:pfam00266 235 S-LQESTFADAPWKFEagTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPER-RASIISF 311
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 61889115 304 PFRIGNSkgdeALEKRFLDK-AVELN------MISLKGHRSVGGIRASLYNAVTTEDVEKL 357
Cdd:pfam00266 312 NFKGVHP----HDVATLLDEsGIAVRsghhcaQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
9-285 |
1.26e-17 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 83.31 E-value: 1.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 9 NFGPGPAKLPYSVLLEiqkqlldykGLGISVLEMSHRSPD----FAKIISntenLVRELLVVPNNYKVIFVQGGGTGQFS 84
Cdd:PRK03080 15 RFSSGPCKKRPGWQLE---------ALADALLGRSHRQKPvkalLKRVIE----GTRELLSLPEGYEVGIVPGSDTGAWE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 85 AVPLNLIGlkaGRCADYVVTGAWSAKAAEEAKKfgtvnivHPKLG-------SYTKIPDPSTwnLNPDASYVyFCANETV 157
Cdd:PRK03080 82 MALWSLLG---ARRVDHLAWESFGSKWATDVVK-------QLKLEdprvleaDYGSLPDLSA--VDFDRDVV-FTWNGTT 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 158 HGVE---FDFIPDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVtvvivrddlLGFAL------------- 221
Cdd:PRK03080 149 TGVRvpvARWIGADREGLTICDATSAAFALPLDWSKLDVYTFSWQKVLGGEGG---------HGMAIlspraverlesyt 219
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 61889115 222 --RECPSVLDY--KVQAGNNSL----YNTPPCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQMIYEIIDNS 285
Cdd:PRK03080 220 paRPIPKFFRLtkGGKAIENSFkgqtINTPSMLTVEDYLDQLDWANSIGGLDALIARTAANASVLYDWAEKT 291
|
|
| PucG |
COG0075 |
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ... |
10-256 |
7.75e-12 |
|
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439845 [Multi-domain] Cd Length: 376 Bit Score: 65.88 E-value: 7.75e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 10 FGPGPAKLPYSVLLEIQKQLLDykglgisvlemsHRSPDFAKIISNTENLVRELLVVPNNykVIFVQGGGTGQFSAVPLN 89
Cdd:COG0075 4 LTPGPTPVPPRVLRAMARPMIG------------HRDPEFVELMDEVRELLKKVFGTEND--VVILTGSGTGAMEAALAN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 90 LIglKAGRCADYVVTGAWSAKAAEEAKKFG--TVNIVHPklgsYTKIPDPSTwnL------NPDASYVYFCANETVHGVE 161
Cdd:COG0075 70 LV--SPGDKVLVLVNGAFGERWAEIAERYGaeVVVLEVP----WGEAVDPEE--VeealaaDPDIKAVAVVHNETSTGVL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 162 FDfIPDV------KGAVLVCD-MSSnFLSRPVDVSKFG--VIFAGAQKNVGS-AGVTVVIVRDDLLGFAL-RECPSV-LD 229
Cdd:COG0075 142 NP-LEEIgalakeHGALLIVDaVSS-LGGVPLDMDEWGidVVVSGSQKCLMLpPGLAFVAVSERALEAIEaRKLPSYyLD 219
|
250 260 270
....*....|....*....|....*....|....*
gi 61889115 230 ----YKVQAGNNSLYnTPPCFSIY----VMDMVLE 256
Cdd:COG0075 220 lklwLKYWEKGQTPY-TPPVSLLYalreALDLILE 253
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
10-295 |
1.34e-11 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 65.00 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 10 FGPGPAKLPYSVLleiqkqlldyKGLGISVLemSHRSPDFAKIISNTENLVRELLvVPNNYKVIFVQGGGTGQFSAVPLN 89
Cdd:cd06451 3 LIPGPSNVPPRVL----------KAMNRPML--GHRSPEFLALMDEILEGLRYVF-QTENGLTFLLSGSGTGAMEAALSN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 90 LigLKAGRCADYVVTGAWSAKAAEEAKKFGT-VNIVHPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDfIPDV 168
Cdd:cd06451 70 L--LEPGDKVLVGVNGVFGDRWADMAERYGAdVDVVEKPWGEAVSPEEIAEALEQHDIKAVTLTHNETSTGVLNP-LEGI 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 169 KGAV------LVCDMSSNFLSRPVDVSKFGV--IFAGAQKNVGS-AGVTVVIVRDDLLGFALRECPSVLDY-------KV 232
Cdd:cd06451 147 GALAkkhdalLIVDAVSSLGGEPFRMDEWGVdvAYTGSQKALGApPGLGPIAFSERALERIKKKTKPKGFYfdlllllKY 226
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 61889115 233 QAGNNSLYNTPPCFSIY----VMDMVLEwiknnGGAAAMEKLSSVKSQMIYEIIDNsQGFYVCPVER 295
Cdd:cd06451 227 WGEGYSYPHTPPVNLLYalreALDLILE-----EGLENRWARHRRLAKALREGLEA-LGLKLLAKPE 287
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
57-213 |
3.38e-08 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 52.77 E-value: 3.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 57 ENLVRELLVvPNNYKVIFVqGGGTGQFSAVPLNLigLKAGRCADYVVTGAWSAKAAEEAKKFGTVNIVHPKLGSYTKIP- 135
Cdd:cd01494 6 EEKLARLLQ-PGNDKAVFV-PSGTGANEAALLAL--LGPGDEVIVDANGHGSRYWVAAELAGAKPVPVPVDDAGYGGLDv 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61889115 136 -DPSTWNLNPDASYVYFCANETVHGV-----EFDFIPDVKGAVLVCDMSSNFLSRP-----VDVSKFGVIFAGAQKNVGS 204
Cdd:cd01494 82 aILEELKAKPNVALIVITPNTTSGGVlvplkEIRKIAKEYGILLLVDAASAGGASPapgvlIPEGGADVVTFSLHKNLGG 161
|
....*....
gi 61889115 205 AGVTVVIVR 213
Cdd:cd01494 162 EGGGVVIVK 170
|
|
| |
