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Conserved domains on  [gi|145864477|ref|NP_964003|]
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UDP glycosyltransferase 1 family, polypeptide A10 precursor [Mus musculus]

Protein Classification

UDP-glycosyltransferase family protein( domain architecture ID 11989770)

UDP-glycosyltransferase family protein similar to UDP-glucuronosyltransferase (UDPGT), which is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds

EC:  2.4.-.-
Gene Ontology:  GO:0008194|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
26-521 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


:

Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 785.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477   26 GRLLVVPMDGSHWFDMQMVVEKLIQRGHEVVVVIPEVSWRLG--KSLNCTVKTYSVSHTLEDLDREFKYFTYTQWKT-PE 102
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEaSF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  103 QSIRSFMtGSARGFFELMFSHSRGLFNDKKLVEYLKQRSFDAVFLDPFDVCGLIVAKYLSLPSVIFARLSFCYYLEEGA- 181
Cdd:pfam00201  81 GTVWSYF-SALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  182 QCPSLLSYVPRLFSKYTDTMTFKERVWNH-YMYIEDYvFCPYFFKTAVEIASEVLQTPVTMTDLFSPVSIWLLRTDFVLE 260
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMlIMLYFDF-WFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  261 FPRPVMPNMVFVGGMNCLQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPS 340
Cdd:pfam00201 239 FPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  341 NLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDL 420
Cdd:pfam00201 319 TLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDL 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  421 ENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVV 500
Cdd:pfam00201 399 LNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVA 478

                         490       500
                  ....*....|....*....|.
gi 145864477  501 FIVFKCCAYGCRKCFGGKGRV 521
Cdd:pfam00201 479 FITFKCCLFGYRKFVGKKKRV 499
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
26-521 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 785.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477   26 GRLLVVPMDGSHWFDMQMVVEKLIQRGHEVVVVIPEVSWRLG--KSLNCTVKTYSVSHTLEDLDREFKYFTYTQWKT-PE 102
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEaSF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  103 QSIRSFMtGSARGFFELMFSHSRGLFNDKKLVEYLKQRSFDAVFLDPFDVCGLIVAKYLSLPSVIFARLSFCYYLEEGA- 181
Cdd:pfam00201  81 GTVWSYF-SALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  182 QCPSLLSYVPRLFSKYTDTMTFKERVWNH-YMYIEDYvFCPYFFKTAVEIASEVLQTPVTMTDLFSPVSIWLLRTDFVLE 260
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMlIMLYFDF-WFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  261 FPRPVMPNMVFVGGMNCLQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPS 340
Cdd:pfam00201 239 FPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  341 NLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDL 420
Cdd:pfam00201 319 TLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDL 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  421 ENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVV 500
Cdd:pfam00201 399 LNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVA 478

                         490       500
                  ....*....|....*....|.
gi 145864477  501 FIVFKCCAYGCRKCFGGKGRV 521
Cdd:pfam00201 479 FITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 28-443 2.04e-74

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 241.30  E-value: 2.04e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  28 LLVVPMDGSHWFDMQMVVEKLIQRGHEVVVVIPEvswrlgkslnctvktYSVSHTLEDLDREFKYFTYTQWKTPEQSIRS 107
Cdd:cd03784    4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPP---------------FNFADLVEAAGLTFVPVGDDPDELELDSETN 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 108 FMTGSARGFFELMFSHSRGLFNDkkLVEYLK-QRSFDAVFLDPFDVCGLIVAKYLSLPSVIFARLSFCYYLEegaqCPSL 186
Cdd:cd03784   69 LGPDSLLELLRRLLKAADELLDD--LLAALRsSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----YLHP 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 187 LSYVPRLFSKYTDTMTFKErvwnhyMYIEDYVFCPYFFKTAVEIASEVLQTPVTMTDLFSPVsiwllrtdFVLEFPRPVM 266
Cdd:cd03784  143 FGVLNLLLSSLLEPELFLD------PLLEVLDRLRERLGLPPFSLVLLLLRLVPPLYVIGPT--------FPSLPPDRPR 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 267 PNMVFVGGMNCLQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPS---NLA 343
Cdd:cd03784  209 LPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRLP 288

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 344 KNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENA 423
Cdd:cd03784  289 DNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKA 368

                        410       420
                 ....*....|....*....|
gi 145864477 424 LKTVINNKSYKENIMRLSSL 443
Cdd:cd03784  369 VREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 14-502 8.24e-45

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 165.13  E-value: 8.24e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  14 VCLLLASGLVQAGRLLVV-PMDG-SHwfdmQMV----VEKLIQRGHEVVVVIPevswrlgKSLNCTVKT--YSVSHTLED 85
Cdd:PHA03392   9 LLLLLLLSGVRAARILAVfPTPAySH----HSVfkvyVEALAERGHNVTVIKP-------TLRVYYASHlcGNITEIDAS 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  86 LDREFkyftYTQWKTPEQSIRSF------MTGSARGFFEL--MFSHSRGLFNDKKLVEYlKQRSFDAV----FLDPFDVC 153
Cdd:PHA03392  78 LSVEY----FKKLVKSSAVFRKRgvvadsSTVTADNYMGLvrMISDQFDLPNVKNLIAN-KNNKFDLLvteaFLDYPLVF 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 154 GLIvakYLSLPsVIfaRLSFCYYLEE-----GAqcpslLSYVPRLF-----SKYTDTMTFKERvwNHyMYIEDYVFCPyf 223
Cdd:PHA03392 153 SHL---FGDAP-VI--QISSGYGLAEnfetmGA-----VSRHPVYYpnlwrSKFGNLNVWETI--NE-IYTELRLYNE-- 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 224 FKTAVEIASEVLQ------TPvTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFVGG--MNCLQGKPLSKEFEAYVNASG 295
Cdd:PHA03392 217 FSLLADEQNKLLKqqfgpdTP-TIRELRNRVQLLFVNVHPVFDNNRPVPPSVQYLGGlhLHKKPPQPLDDYLEEFLNNST 295

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 296 EhGIVVFSLGSMVseipEKKAM------EIAEALGRIPQTVLWRYTGT-RPSNLAKNTILVKWLPQNDLLGHPKTRAFIT 368
Cdd:PHA03392 296 N-GVVYVSFGSSI----DTNDMdneflqMLLRTFKKLPYNVLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVT 370

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 369 HSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRP 448
Cdd:PHA03392 371 QGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQP 450

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 145864477 449 IEPLDLAVFWVEYVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAIVLTVVFI 502
Cdd:PHA03392 451 MTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPLVTFTVM 501
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
227-441 1.81e-32

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 125.35  E-value: 1.81e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 227 AVEIASEVLQTPVTMtdLFSPVsiwllrtdfvLEFPRPVMP-NMVFVGgmNCLQGKPlsKEFEAYVNASGEHGIVVFSLG 305
Cdd:COG1819   65 AAALAAEALGIPVVS--LTPPE----------LEYPRPPDPaNVRFVG--PLLPDGP--AELPPWLEEDAGRPLVYVTLG 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 306 SMVSEIPEKKAMeIAEALGRIPQTVLWRYTGTRPSNLAK---NTILVKWLPQNDLLghPKTRAFITHSGSHGIYEGICNG 382
Cdd:COG1819  129 TSANDRADLLRA-VLEALADLGVRVVVTTGGLDPAELGPlpdNVRVVDYVPQDALL--PRADAVVHHGGAGTTAEALRAG 205

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 145864477 383 VPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLS 441
Cdd:COG1819  206 VPQVVVPFGGDQPLNAARVERLGAGLALPPRRLTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 44-440 6.31e-21

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 94.75  E-value: 6.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477   44 VVEKLIQRGHEVVVVIPEVSWRLGKSLNCTVKTYSVSHTLEDLDREfkYFTYTQWKTPEQSIRsfMTGSArgfFELMFSH 123
Cdd:TIGR01426  15 VVEELVARGHRVTYATTEEFAERVEAAGAEFVLYGSALPPPDNPPE--NTEEEPIDIIEKLLD--EAEDV---LPQLEEA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  124 SRGlfnDKklveylkqrsFDAVFLDPFDVCGLIVAKYLSLPSV-IFArlSFCYY--------------LEEGAQCP-SLL 187
Cdd:TIGR01426  88 YKG---DR----------PDLIVYDIASWTGRLLARKWDVPVIsSFP--TFAANeefeemvspagegsAEEGAIAErGLA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  188 SYVPRLFSkytdtmtFKERvwnhymyiedyvfcpyFFKTAVEIAsevlqtpvtmtDLFSPvsiwllRTDFVLEF-PRPVM 266
Cdd:TIGR01426 153 EYVARLSA-------LLEE----------------HGITTPPVE-----------FLAAP------RRDLNLVYtPKAFQ 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  267 PNMVFVGGMNCLQGKPL---SKEFEAYVNASGeHGIVVFSLGSMVSEIPEKKAMeIAEALGRIP-QTVLWRYTGTRPSNL 342
Cdd:TIGR01426 193 PAGETFDDSFTFVGPCIgdrKEDGSWERPGDG-RPVVLISLGTVFNNQPSFYRT-CVEAFRDLDwHVVLSVGRGVDPADL 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  343 A---KNTILVKWLPQNDLLghPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADD 419
Cdd:TIGR01426 271 GelpPNVEVRQWVPQLEIL--KKADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEK 348

                         410       420
                  ....*....|....*....|.
gi 145864477  420 LENALKTVINNKSYKENIMRL 440
Cdd:TIGR01426 349 LREAVLAVLSDPRYAERLRKM 369
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
26-521 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 785.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477   26 GRLLVVPMDGSHWFDMQMVVEKLIQRGHEVVVVIPEVSWRLG--KSLNCTVKTYSVSHTLEDLDREFKYFTYTQWKT-PE 102
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEaSF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  103 QSIRSFMtGSARGFFELMFSHSRGLFNDKKLVEYLKQRSFDAVFLDPFDVCGLIVAKYLSLPSVIFARLSFCYYLEEGA- 181
Cdd:pfam00201  81 GTVWSYF-SALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  182 QCPSLLSYVPRLFSKYTDTMTFKERVWNH-YMYIEDYvFCPYFFKTAVEIASEVLQTPVTMTDLFSPVSIWLLRTDFVLE 260
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMlIMLYFDF-WFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  261 FPRPVMPNMVFVGGMNCLQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPS 340
Cdd:pfam00201 239 FPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  341 NLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDL 420
Cdd:pfam00201 319 TLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDL 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  421 ENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVV 500
Cdd:pfam00201 399 LNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVA 478

                         490       500
                  ....*....|....*....|.
gi 145864477  501 FIVFKCCAYGCRKCFGGKGRV 521
Cdd:pfam00201 479 FITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 28-443 2.04e-74

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 241.30  E-value: 2.04e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  28 LLVVPMDGSHWFDMQMVVEKLIQRGHEVVVVIPEvswrlgkslnctvktYSVSHTLEDLDREFKYFTYTQWKTPEQSIRS 107
Cdd:cd03784    4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPP---------------FNFADLVEAAGLTFVPVGDDPDELELDSETN 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 108 FMTGSARGFFELMFSHSRGLFNDkkLVEYLK-QRSFDAVFLDPFDVCGLIVAKYLSLPSVIFARLSFCYYLEegaqCPSL 186
Cdd:cd03784   69 LGPDSLLELLRRLLKAADELLDD--LLAALRsSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----YLHP 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 187 LSYVPRLFSKYTDTMTFKErvwnhyMYIEDYVFCPYFFKTAVEIASEVLQTPVTMTDLFSPVsiwllrtdFVLEFPRPVM 266
Cdd:cd03784  143 FGVLNLLLSSLLEPELFLD------PLLEVLDRLRERLGLPPFSLVLLLLRLVPPLYVIGPT--------FPSLPPDRPR 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 267 PNMVFVGGMNCLQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPS---NLA 343
Cdd:cd03784  209 LPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRLP 288

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 344 KNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENA 423
Cdd:cd03784  289 DNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKA 368

                        410       420
                 ....*....|....*....|
gi 145864477 424 LKTVINNKSYKENIMRLSSL 443
Cdd:cd03784  369 VREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 14-502 8.24e-45

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 165.13  E-value: 8.24e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  14 VCLLLASGLVQAGRLLVV-PMDG-SHwfdmQMV----VEKLIQRGHEVVVVIPevswrlgKSLNCTVKT--YSVSHTLED 85
Cdd:PHA03392   9 LLLLLLLSGVRAARILAVfPTPAySH----HSVfkvyVEALAERGHNVTVIKP-------TLRVYYASHlcGNITEIDAS 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  86 LDREFkyftYTQWKTPEQSIRSF------MTGSARGFFEL--MFSHSRGLFNDKKLVEYlKQRSFDAV----FLDPFDVC 153
Cdd:PHA03392  78 LSVEY----FKKLVKSSAVFRKRgvvadsSTVTADNYMGLvrMISDQFDLPNVKNLIAN-KNNKFDLLvteaFLDYPLVF 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 154 GLIvakYLSLPsVIfaRLSFCYYLEE-----GAqcpslLSYVPRLF-----SKYTDTMTFKERvwNHyMYIEDYVFCPyf 223
Cdd:PHA03392 153 SHL---FGDAP-VI--QISSGYGLAEnfetmGA-----VSRHPVYYpnlwrSKFGNLNVWETI--NE-IYTELRLYNE-- 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 224 FKTAVEIASEVLQ------TPvTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFVGG--MNCLQGKPLSKEFEAYVNASG 295
Cdd:PHA03392 217 FSLLADEQNKLLKqqfgpdTP-TIRELRNRVQLLFVNVHPVFDNNRPVPPSVQYLGGlhLHKKPPQPLDDYLEEFLNNST 295

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 296 EhGIVVFSLGSMVseipEKKAM------EIAEALGRIPQTVLWRYTGT-RPSNLAKNTILVKWLPQNDLLGHPKTRAFIT 368
Cdd:PHA03392 296 N-GVVYVSFGSSI----DTNDMdneflqMLLRTFKKLPYNVLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVT 370

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 369 HSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRP 448
Cdd:PHA03392 371 QGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQP 450

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 145864477 449 IEPLDLAVFWVEYVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAIVLTVVFI 502
Cdd:PHA03392 451 MTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPLVTFTVM 501
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
227-441 1.81e-32

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 125.35  E-value: 1.81e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 227 AVEIASEVLQTPVTMtdLFSPVsiwllrtdfvLEFPRPVMP-NMVFVGgmNCLQGKPlsKEFEAYVNASGEHGIVVFSLG 305
Cdd:COG1819   65 AAALAAEALGIPVVS--LTPPE----------LEYPRPPDPaNVRFVG--PLLPDGP--AELPPWLEEDAGRPLVYVTLG 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 306 SMVSEIPEKKAMeIAEALGRIPQTVLWRYTGTRPSNLAK---NTILVKWLPQNDLLghPKTRAFITHSGSHGIYEGICNG 382
Cdd:COG1819  129 TSANDRADLLRA-VLEALADLGVRVVVTTGGLDPAELGPlpdNVRVVDYVPQDALL--PRADAVVHHGGAGTTAEALRAG 205

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 145864477 383 VPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLS 441
Cdd:COG1819  206 VPQVVVPFGGDQPLNAARVERLGAGLALPPRRLTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 44-440 6.31e-21

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 94.75  E-value: 6.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477   44 VVEKLIQRGHEVVVVIPEVSWRLGKSLNCTVKTYSVSHTLEDLDREfkYFTYTQWKTPEQSIRsfMTGSArgfFELMFSH 123
Cdd:TIGR01426  15 VVEELVARGHRVTYATTEEFAERVEAAGAEFVLYGSALPPPDNPPE--NTEEEPIDIIEKLLD--EAEDV---LPQLEEA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  124 SRGlfnDKklveylkqrsFDAVFLDPFDVCGLIVAKYLSLPSV-IFArlSFCYY--------------LEEGAQCP-SLL 187
Cdd:TIGR01426  88 YKG---DR----------PDLIVYDIASWTGRLLARKWDVPVIsSFP--TFAANeefeemvspagegsAEEGAIAErGLA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  188 SYVPRLFSkytdtmtFKERvwnhymyiedyvfcpyFFKTAVEIAsevlqtpvtmtDLFSPvsiwllRTDFVLEF-PRPVM 266
Cdd:TIGR01426 153 EYVARLSA-------LLEE----------------HGITTPPVE-----------FLAAP------RRDLNLVYtPKAFQ 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  267 PNMVFVGGMNCLQGKPL---SKEFEAYVNASGeHGIVVFSLGSMVSEIPEKKAMeIAEALGRIP-QTVLWRYTGTRPSNL 342
Cdd:TIGR01426 193 PAGETFDDSFTFVGPCIgdrKEDGSWERPGDG-RPVVLISLGTVFNNQPSFYRT-CVEAFRDLDwHVVLSVGRGVDPADL 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  343 A---KNTILVKWLPQNDLLghPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADD 419
Cdd:TIGR01426 271 GelpPNVEVRQWVPQLEIL--KKADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEK 348

                         410       420
                  ....*....|....*....|.
gi 145864477  420 LENALKTVINNKSYKENIMRL 440
Cdd:TIGR01426 349 LREAVLAVLSDPRYAERLRKM 369
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 264-402 8.48e-13

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 70.45  E-value: 8.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 264 PVMPnmvfVGGMNCLQGKPLS-----KEFEAYVNASGEHGIVVFSLGSM-VSEIPEkkAMEIAEALGRIPQTVLW----- 332
Cdd:PLN02410 230 PVYP----IGPLHLVASAPTSlleenKSCIEWLNKQKKNSVIFVSLGSLaLMEINE--VMETASGLDSSNQQFLWvirpg 303

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145864477 333 -----RYTGTRPSNLAK----NTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRME 402
Cdd:PLN02410 304 svrgsEWIESLPKEFSKiisgRGYIVKWAPQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 253-402 1.03e-12

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 70.08  E-value: 1.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 253 LRTDFVLEFPR-------PVMPNMVFVGGMNclqGKPLSKE-----FEAYVNASGEHGIVVFSLGSMVsEIPEKKAMEIA 320
Cdd:PLN02152 208 LEPEFLTAIPNiemvavgPLLPAEIFTGSES---GKDLSVRdqsssYTLWLDSKTESSVIYVSFGTMV-ELSKKQIEELA 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 321 EALGRIPQTVLWRYT----------GTRPSNLAKNT----------ILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGIC 380
Cdd:PLN02152 284 RALIEGKRPFLWVITdklnreakieGEEETEIEKIAgfrheleevgMIVSWCSQIEVLRHRAVGCFVTHCGWSSSLESLV 363

                        170       180
                 ....*....|....*....|..
gi 145864477 381 NGVPMVMMPLFGDQMDNAKRME 402
Cdd:PLN02152 364 LGVPVVAFPMWSDQPANAKLLE 385
PLN00164 PLN00164
glucosyltransferase; Provisional
 300-398 6.09e-10

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 61.61  E-value: 6.09e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 300 VVF-SLGSMVSeIPEKKAMEIAEALGRIPQTVLWRYTGTRP--------SNLA-----------KNTILV--KWLPQNDL 357
Cdd:PLN00164 274 VVFlCFGSMGF-FDAPQVREIAAGLERSGHRFLWVLRGPPAagsrhptdADLDellpegflertKGRGLVwpTWAPQKEI 352

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 145864477 358 LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN00164 353 LAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNA 393
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 290-443 1.40e-09

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 60.43  E-value: 1.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 290 YVNASGEHGIVVFSLGSMvSEIPEKKAMEIAEALGRIpqTVLWRYTGTRPSNL---------AKNTILVKWLPQNDLLGH 360
Cdd:PLN02173 257 WLDKRPQGSVVYIAFGSM-AKLSSEQMEEIASAISNF--SYLWVVRASEESKLppgfletvdKDKSLVLKWSPQLQVLSN 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 361 PKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRME-TRGAGVTLNVLEMTA----DDLENALKTVIN---NKS 432
Cdd:PLN02173 334 KAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQdVWKVGVRVKAEKESGiakrEEIEFSIKEVMEgekSKE 413

                        170
                 ....*....|.
gi 145864477 433 YKENIMRLSSL 443
Cdd:PLN02173 414 MKENAGKWRDL 424
PLN02534 PLN02534
UDP-glycosyltransferase
 294-412 3.01e-09

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 59.49  E-value: 3.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 294 SGEHGIVVF-SLGSMVSEIPeKKAMEIAEALGRIPQTVLWRY-TGTRPSNLAK-------------NTILVK-WLPQNDL 357
Cdd:PLN02534 279 SMKPRSVIYaCLGSLCRLVP-SQLIELGLGLEASKKPFIWVIkTGEKHSELEEwlvkenfeerikgRGLLIKgWAPQVLI 357

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 145864477 358 LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRM-ETRGAGVTLNV 412
Cdd:PLN02534 358 LSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLIvEVLRIGVRVGV 413
PLN02210 PLN02210
UDP-glucosyl transferase
 229-425 7.39e-09

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 58.12  E-value: 7.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 229 EIASEVLQTpvtMTDLFSPVSIWLLrtdfvlefprpVMPNMVFVGGMNCLQGKPL----SKEF-EAYVNASGEHGIVVFS 303
Cdd:PLN02210 210 ELESEIIES---MADLKPVIPIGPL-----------VSPFLLGDDEEETLDGKNLdmckSDDCcMEWLDKQARSSVVYIS 275

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 304 LGSMVSEIpEKKAMEIAEALGRIPQTVLWRytgTRPSNLAKNT------------ILVKWLPQNDLLGHPKTRAFITHSG 371
Cdd:PLN02210 276 FGSMLESL-ENQVETIAKALKNRGVPFLWV---IRPKEKAQNVqvlqemvkegqgVVLEWSPQEKILSHMAISCFVTHCG 351

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 145864477 372 SHGIYEGICNGVPMVMMPLFGDQMDNAKRM-ETRGAGVtlnvlEMTADDLENALK 425
Cdd:PLN02210 352 WNSTIETVVAGVPVVAYPSWTDQPIDARLLvDVFGIGV-----RMRNDAVDGELK 401
PLN02555 PLN02555
limonoid glucosyltransferase
 348-401 1.73e-08

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 56.73  E-value: 1.73e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 145864477 348 LVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRM 401
Cdd:PLN02555 341 IVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYL 394
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 264-399 2.10e-08

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 56.55  E-value: 2.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 264 PVMPNMVFVGGMNCLQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSeIPEKKAMEIAEALGRIPQTVLW--RYTGTRPSN 341
Cdd:PLN02448 241 PSIPYMELKDNSSSSNNEDNEPDYFQWLDSQPEGSVLYVSLGSFLS-VSSAQMDEIAAGLRDSGVRFLWvaRGEASRLKE 319

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 145864477 342 LAKNT-ILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAK 399
Cdd:PLN02448 320 ICGDMgLVVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNSK 378
PLN02207 PLN02207
UDP-glycosyltransferase
 133-443 7.15e-08

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 55.04  E-value: 7.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 133 LVEYLKQRSFDAVFLDPFdvcgliVAKYLSLPSVIFAR---LSFCYYLEEGAQCPSLLSYVPRLFSKytDTMTFKERVwn 209
Cdd:PLN02207 102 VMDILSSLALDGVKVKGF------VADFFCLPMIDVAKdvsLPFYVFLTTNSGFLAMMQYLADRHSK--DTSVFVRNS-- 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 210 hymyiEDYVFCPYFFKTaveIASEVLQTPVTMTD----------LFSPVSIWLLRTDFVLEfPRPV--------MPNMVF 271
Cdd:PLN02207 172 -----EEMLSIPGFVNP---VPANVLPSALFVEDgydayvklaiLFTKANGILVNSSFDIE-PYSVnhfldeqnYPSVYA 242

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 272 VGGMNCLQGKP-----LSK--EFEAYVNASGEHGIVVFSLGSMVSeIPEKKAMEIAEALGRIPQTVLWRYTGTRPSN--- 341
Cdd:PLN02207 243 VGPIFDLKAQPhpeqdLARrdELMKWLDDQPEASVVFLCFGSMGR-LRGPLVKEIAHGLELCQYRFLWSLRTEEVTNddl 321

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 342 --------LAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRM--ETRGAgVTLN 411
Cdd:PLN02207 322 lpegfldrVSGRGMICGWSPQVEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNAFLMvkELKLA-VELK 400

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 145864477 412 VLE-------MTADDLENALKTVIN--NKSYKENIMRLSSL 443
Cdd:PLN02207 401 LDYrvhsdeiVNANEIETAIRCVMNkdNNVVRKRVMDISQM 441
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 351-398 8.37e-08

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 54.60  E-value: 8.37e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 145864477 351 WLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNA 392
PLN03015 PLN03015
UDP-glucosyl transferase
 290-418 8.46e-08

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 54.70  E-value: 8.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 290 YVNASGEHGIVVFSLGSMvSEIPEKKAMEIAEALGRIPQTVLW------RYTG-----------TRPSNLAKNT-----I 347
Cdd:PLN03015 260 WLDKQGERSVVYVCLGSG-GTLTFEQTVELAWGLELSGQRFVWvlrrpaSYLGasssdddqvsaSLPEGFLDRTrgvglV 338

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 145864477 348 LVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKrMETRGAGVTLNVLEMTAD 418
Cdd:PLN03015 339 VTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNAT-LLTEEIGVAVRTSELPSE 408
PLN03004 PLN03004
UDP-glycosyltransferase
 290-442 9.10e-08

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 54.70  E-value: 9.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 290 YVNASGEHGIVVFSLGSMvSEIPEKKAMEIAEALGRIPQTVLWryTGTRPSNLAKNTILVK------------------- 350
Cdd:PLN03004 263 WLDSQPEKSVVFLCFGSL-GLFSKEQVIEIAVGLEKSGQRFLW--VVRNPPELEKTELDLKsllpegflsrtedkgmvvk 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 351 -WLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRM-ETRGAGVTLNVLE---MTADDLENALK 425
Cdd:PLN03004 340 sWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMIvDEIKIAISMNESEtgfVSSTEVEKRVQ 419

                        170
                 ....*....|....*..
gi 145864477 426 TVINNKSYKENIMRLSS 442
Cdd:PLN03004 420 EIIGECPVRERTMAMKN 436
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 300-432 1.44e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 54.02  E-value: 1.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 300 VVF-SLGSMvSEIPEKKAMEIAEALGRIPQTVLWRYTGTRP----------SNLAKntIL--------------VKWLPQ 354
Cdd:PLN02554 276 VVFlCFGSM-GGFSEEQAREIAIALERSGHRFLWSLRRASPnimkeppgefTNLEE--ILpegfldrtkdigkvIGWAPQ 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 355 NDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRM------------ETRGAGVTLNVLEMTADDLEN 422
Cdd:PLN02554 353 VAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMveelglaveirkYWRGDLLAGEMETVTAEEIER 432

                        170
                 ....*....|
gi 145864477 423 ALKTVINNKS 432
Cdd:PLN02554 433 GIRCLMEQDS 442
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 299-443 1.95e-07

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 53.71  E-value: 1.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 299 IVVFSLGSMVSeIPEKKAMEIAEALGRIPQTVLW--RYTGTRPSN------------LAKNTILVKWLPQNDLLGHPKTR 364
Cdd:PLN03007 287 VIYLSFGSVAS-FKNEQLFEIAAGLEGSGQNFIWvvRKNENQGEKeewlpegfeertKGKGLIIRGWAPQVLILDHQATG 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 365 AFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRM-ETRGAGVTLNVLEM--------TADDLENALKTVINNKSYKE 435
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKLvkvkgdfiSREKVEKAVREVIVGEEAEE 445


                 ....*...
gi 145864477 436 NIMRLSSL 443
Cdd:PLN03007 446 RRLRAKKL 453
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 261-401 5.38e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 52.11  E-value: 5.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 261 FPrPVMPnmvfVGGMNCLQGKPLS-------KEFEAYVNASGEHGIVVFSLGSMVSeIPEKKAMEIAEALGRIPQTVLW- 332
Cdd:PLN02167 242 YP-PVYP----VGPILSLKDRTSPnldssdrDRIMRWLDDQPESSVVFLCFGSLGS-LPAPQIKEIAQALELVGCRFLWs 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 333 -RYTGTRPSN------------LAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAK 399
Cdd:PLN02167 316 iRTNPAEYASpyeplpegfmdrVMGRGLVCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNAF 395


                 ..
gi 145864477 400 RM 401
Cdd:PLN02167 396 TM 397
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 347-398 8.52e-07

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 51.41  E-value: 8.52e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 145864477 347 ILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN02863 346 VIRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQFVNA 397
PLN02562 PLN02562
UDP-glycosyltransferase
 275-440 1.82e-06

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 50.26  E-value: 1.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 275 MNCLQgkplskefeaYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGT-----------RPSNLA 343
Cdd:PLN02562 261 MSCLG----------WLQEQKPNSVIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNPVwreglppgyveRVSKQG 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 344 KntiLVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRM-ETRGAGVTLNvlEMTADDLEN 422
Cdd:PLN02562 331 K---VVSWAPQLEVLKHQAVGCYLTHCGWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIvDVWKIGVRIS--GFGQKEVEE 405

                        170
                 ....*....|....*...
gi 145864477 423 ALKTVINNKSYKENIMRL 440
Cdd:PLN02562 406 GLRKVMEDSGMGERLMKL 423
PLN02208 PLN02208
glycosyltransferase family protein
 351-432 7.47e-05

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 45.39  E-value: 7.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 351 WLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMdNAKRMETRGAGVTLNVLE-----MTADDLENALK 425
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQV-LFTRLMTEEFEVSVEVSRektgwFSKESLSNAIK 396


                 ....*..
gi 145864477 426 TVINNKS 432
Cdd:PLN02208 397 SVMDKDS 403
PLN02670 PLN02670
transferase, transferring glycosyl groups
 347-408 1.39e-04

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 44.51  E-value: 1.39e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 145864477 347 ILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGV 408
Cdd:PLN02670 342 IHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGL 403
PLN00414 PLN00414
glycosyltransferase family protein
 298-439 1.91e-04

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 43.86  E-value: 1.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 298 GIVVFSLGSMVSEIPEKKAMEIAEALgriPQTVLWRYTGtrpsnlaKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYE 377
Cdd:PLN00414 276 GMELTGLPFLIAVMPPKGSSTVQEAL---PEGFEERVKG-------RGIVWEGWVEQPLILSHPSVGCFVNHCGFGSMWE 345

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 145864477 378 GICNGVPMVMMPLFGDQMdNAKRMETRGAGVTLNVLE-----MTADDLENALKTVINNKSYKENIMR 439
Cdd:PLN00414 346 SLVSDCQIVFIPQLADQV-LITRLLTEELEVSVKVQRedsgwFSKESLRDTVKSVMDKDSEIGNLVK 411
PLN02764 PLN02764
glycosyltransferase family protein
 307-439 8.89e-04

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 41.97  E-value: 8.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 307 MVSEIPEKKAMEIAEALgriPQTVLWRYTGtrpsnlaKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMV 386
Cdd:PLN02764 290 LVAVKPPRGSSTIQEAL---PEGFEERVKG-------RGVVWGGWVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIV 359

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 145864477 387 MMPLFGDQMDNAKRMETRgAGVTLNVLE-----MTADDLENALKTVINNKSYKENIMR 439
Cdd:PLN02764 360 LVPQLGDQVLNTRLLSDE-LKVSVEVAReetgwFSKESLRDAINSVMKRDSEIGNLVK 416
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 367-447 1.11e-03

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 40.00  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477  367 ITHSGSHGIYEGICNGVPMVMMPL----FGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSS 442
Cdd:pfam04101  76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASK 155


                  ....*
gi 145864477  443 LHKDR 447
Cdd:pfam04101 156 ASGFK 160
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 367-441 1.97e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 40.66  E-value: 1.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 367 ITHSGSHGIYEGICNGVPMVMMPLF----GDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINN----KSYKENIM 438
Cdd:cd03785  257 ISRAGASTIAELTAAGKPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDperlKKMAEAAK 336


                 ...
gi 145864477 439 RLS 441
Cdd:cd03785  337 KLA 339
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 367-441 2.58e-03

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 40.11  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145864477 367 ITHSGSHGIYEGICNGVPMVMMPL-F---GDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINN----KSYKENIM 438
Cdd:COG0707  263 ISRAGASTVAELAALGKPAILVPLpHaadDHQTKNARALVEAGAAVLIPQSELTPEKLAEALEELLEDperlAKMAEAAR 342


                 ...
gi 145864477 439 RLS 441
Cdd:COG0707  343 ALA 345
PIN_Zc3h12a-N4BP1-like cd18719
PRORP-like PIN domain of ribonuclease Zc3h12a, NEDD4-binding partner-1, and related proteins; ...
 31-96 2.98e-03

PRORP-like PIN domain of ribonuclease Zc3h12a, NEDD4-binding partner-1, and related proteins; Zc3h12a (zinc finger CCCH-type containing 12A, also known as MCPIP1/MCP induced protein 1 and Regnase-1) is a critical regulator of inflammatory response, with additional roles in defense against viruses and various stresses, cellular differentiation, and apoptosis. This subfamily also includes Caenorhabditis elegans REGE-1 (REGnasE-1), which also functions as a cytoplasmic endonuclease. Additionally, it includes three less-studied mammalian homologs: Zc3h12b-d/Regnase-2-4, as well as N4BP1 (NEDD4-binding partner-1), NYNRIN (NYN domain and retroviral integrase containing, also known as CGIN1/Cousin of GIN1), and KHNYN (KH and NYN domain containing) protein. N4BP1, CGIN1, and KHNYN proteins are probably of retroviral origin. This subfamily belongs to the PRORP-Zc3h12a-like PIN family which in addition includes human PRORP, also known as proteinaceous RNase P and mitochondrial RNase P protein subunit 3 (MRPP3), and Arabidopsis thaliana PRORP1-3. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.


Pssm-ID: 350286  Cd Length: 127  Bit Score: 37.95  E-value: 2.98e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 145864477  31 VPMDGS---------HWFD---MQMVVEKLIQRGHEVVVVIPEvsWRlgksLNCTVKTYSVSHTLEDLDREfKYFTYT 96
Cdd:cd18719    1 VVIDGSnvamshgngKVFSckgIQICVRYFLERGHEVTAFVPQ--FR----LESPNPNSTDQDILEELERL-GILVFT 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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