NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|42571789|ref|NP_973985|]
View 

Scorpion toxin-like knottin superfamily protein [Arabidopsis thaliana]

Protein Classification

neurotoxins_LC_scorpion domain-containing protein( domain architecture ID 10455478)

neurotoxins_LC_scorpion domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Toxin_3 pfam00537
Scorpion toxin-like domain; This family contains both neurotoxins and plant defensins. The ...
 29-91 7.35e-13

Scorpion toxin-like domain; This family contains both neurotoxins and plant defensins. The mustard trypsin inhibitor, MTI-2, is plant defensin. It is a potent inhibitor of trypsin with no activity towards chymotrypsin. MTI-2 is toxic for Lepidopteran insects, but has low activity against aphids. Brazzein is plant defensin-like protein. It is pH-stable, heat-stable and intensely sweet protein. The scorpion toxin (a neurotoxin) binds to sodium channels and inhibits the activation mechanisms of the channels, thereby blocking neuronal transmission. Scorpion toxins bind to sodium channels and inhibit the activation mechanisms of the channels, thereby blocking neuronal transmission


:

Pssm-ID: 395428  Cd Length: 55  Bit Score: 57.71  E-value: 7.35e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 42571789   29 YDRKCLKEYGGDVgfsYCAPRifPTFCDQNCRKNkGAKGGVCRWEEnnAIGVKCLCNFCSEEP 91
Cdd:pfam00537  1 RDGYIAKEYNCVY---SCAPR--NSYCDKLCKKN-GAKSGYCQWGG--GYGNACWCYGLPDNV 55
 
Name Accession Description Interval E-value
Toxin_3 pfam00537
Scorpion toxin-like domain; This family contains both neurotoxins and plant defensins. The ...
 29-91 7.35e-13

Scorpion toxin-like domain; This family contains both neurotoxins and plant defensins. The mustard trypsin inhibitor, MTI-2, is plant defensin. It is a potent inhibitor of trypsin with no activity towards chymotrypsin. MTI-2 is toxic for Lepidopteran insects, but has low activity against aphids. Brazzein is plant defensin-like protein. It is pH-stable, heat-stable and intensely sweet protein. The scorpion toxin (a neurotoxin) binds to sodium channels and inhibits the activation mechanisms of the channels, thereby blocking neuronal transmission. Scorpion toxins bind to sodium channels and inhibit the activation mechanisms of the channels, thereby blocking neuronal transmission


Pssm-ID: 395428  Cd Length: 55  Bit Score: 57.71  E-value: 7.35e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 42571789   29 YDRKCLKEYGGDVgfsYCAPRifPTFCDQNCRKNkGAKGGVCRWEEnnAIGVKCLCNFCSEEP 91
Cdd:pfam00537  1 RDGYIAKEYNCVY---SCAPR--NSYCDKLCKKN-GAKSGYCQWGG--GYGNACWCYGLPDNV 55
 
Name Accession Description Interval E-value
Toxin_3 pfam00537
Scorpion toxin-like domain; This family contains both neurotoxins and plant defensins. The ...
 29-91 7.35e-13

Scorpion toxin-like domain; This family contains both neurotoxins and plant defensins. The mustard trypsin inhibitor, MTI-2, is plant defensin. It is a potent inhibitor of trypsin with no activity towards chymotrypsin. MTI-2 is toxic for Lepidopteran insects, but has low activity against aphids. Brazzein is plant defensin-like protein. It is pH-stable, heat-stable and intensely sweet protein. The scorpion toxin (a neurotoxin) binds to sodium channels and inhibits the activation mechanisms of the channels, thereby blocking neuronal transmission. Scorpion toxins bind to sodium channels and inhibit the activation mechanisms of the channels, thereby blocking neuronal transmission


Pssm-ID: 395428  Cd Length: 55  Bit Score: 57.71  E-value: 7.35e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 42571789   29 YDRKCLKEYGGDVgfsYCAPRifPTFCDQNCRKNkGAKGGVCRWEEnnAIGVKCLCNFCSEEP 91
Cdd:pfam00537  1 RDGYIAKEYNCVY---SCAPR--NSYCDKLCKKN-GAKSGYCQWGG--GYGNACWCYGLPDNV 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH