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Conserved domains on  [gi|45383808|ref|NP_989483|]
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large ribosomal subunit protein eL6 [Gallus gallus]

Protein Classification

Ribosomal_L6e_N and KOW_RPL6 domain-containing protein( domain architecture ID 10511091)

Ribosomal_L6e_N and KOW_RPL6 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
KOW_RPL6 cd13156
KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as ...
146-298 1.69e-83

KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as an oncogenic. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4.


:

Pssm-ID: 240520  Cd Length: 152  Bit Score: 247.85  E-value: 1.69e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808 146 HKRRLRASITPGTVLILLTGRHRGKRVVFLKQLGTGLLLVTGPLAVNRVPLRRAHQKFVIATSTKVDISGVKIPkHLTDA 225
Cdd:cd13156   1 KPRKLRSSITPGTVLILLAGRFRGKRVVFLKQLDSGLLLVTGPFKINGVPLRRVNQRYVIATSTKVDISGVKVP-KLNDA 79
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 45383808 226 YFKKKKLRKPKHQEGEIFDTEKEKYEITEQRKTDQKAVDSQILARIKKVPQLRGYLRSTFSLSNGVYPHKLVF 298
Cdd:cd13156  80 YFKRKKKKKKKKKEGEFFEEKKKKYVVSEERKEDQKAVDAALLAAIKKVPLLKGYLKSRFSLRNGDYPHKMKF 152
Ribosomal_L6e_N pfam03868
Ribosomal protein L6, N-terminal domain;
47-105 5.13e-15

Ribosomal protein L6, N-terminal domain;


:

Pssm-ID: 427554  Cd Length: 60  Bit Score: 68.12  E-value: 5.13e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45383808    47 KKPKKYHASRNPVLARGIGKYSRSAMYARKALYKRKYTAPETKIEKKKKEKPRATIIKP 105
Cdd:pfam03868   2 PKKGKPHCSRNPVLVRGIGRYSRSAMYSRKAMYKRKYSATKSKIEKKKKEKVLATVTKP 60
valS super family cl36437
valyl-tRNA synthetase; Provisional
5-56 4.10e-05

valyl-tRNA synthetase; Provisional


The actual alignment was detected with superfamily member PRK14900:

Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 44.98  E-value: 4.10e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 45383808     5 KKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKKVREKI-KKPKKYHASR 56
Cdd:PRK14900  998 KKAPAKKAAAKKAAAKKAAAKKKVAKKAPAKKVARKPAAKKAaKKPARKAAGR 1050
 
Name Accession Description Interval E-value
KOW_RPL6 cd13156
KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as ...
146-298 1.69e-83

KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as an oncogenic. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4.


Pssm-ID: 240520  Cd Length: 152  Bit Score: 247.85  E-value: 1.69e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808 146 HKRRLRASITPGTVLILLTGRHRGKRVVFLKQLGTGLLLVTGPLAVNRVPLRRAHQKFVIATSTKVDISGVKIPkHLTDA 225
Cdd:cd13156   1 KPRKLRSSITPGTVLILLAGRFRGKRVVFLKQLDSGLLLVTGPFKINGVPLRRVNQRYVIATSTKVDISGVKVP-KLNDA 79
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 45383808 226 YFKKKKLRKPKHQEGEIFDTEKEKYEITEQRKTDQKAVDSQILARIKKVPQLRGYLRSTFSLSNGVYPHKLVF 298
Cdd:cd13156  80 YFKRKKKKKKKKKEGEFFEEKKKKYVVSEERKEDQKAVDAALLAAIKKVPLLKGYLKSRFSLRNGDYPHKMKF 152
Ribosomal_L6e pfam01159
Ribosomal protein L6e;
191-298 1.49e-53

Ribosomal protein L6e;


Pssm-ID: 460089  Cd Length: 109  Bit Score: 170.01  E-value: 1.49e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808   191 VNRVPLRRAHQKFVIATSTKVDISGVKIPKHLTDAYFK-KKKLRKPKHQEGEIFDTEKEKYEITEQRKTDQKAVDSQILA 269
Cdd:pfam01159   1 VNGVPLRRVNQRYVIATSTKVDISGVKIPEHINDAYFKkEKKKKKKPKSEEEFFEEKKEKKEVSEQRKADQKAVDKALLA 80
                          90       100
                  ....*....|....*....|....*....
gi 45383808   270 RIKKVPQLRGYLRSTFSLSNGVYPHKLVF 298
Cdd:pfam01159  81 AIKKVPLLKGYLKSSFSLRKGDYPHEMKF 109
Ribosomal_L6e_N pfam03868
Ribosomal protein L6, N-terminal domain;
47-105 5.13e-15

Ribosomal protein L6, N-terminal domain;


Pssm-ID: 427554  Cd Length: 60  Bit Score: 68.12  E-value: 5.13e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45383808    47 KKPKKYHASRNPVLARGIGKYSRSAMYARKALYKRKYTAPETKIEKKKKEKPRATIIKP 105
Cdd:pfam03868   2 PKKGKPHCSRNPVLVRGIGRYSRSAMYSRKAMYKRKYSATKSKIEKKKKEKVLATVTKP 60
valS PRK14900
valyl-tRNA synthetase; Provisional
5-56 4.10e-05

valyl-tRNA synthetase; Provisional


Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 44.98  E-value: 4.10e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 45383808     5 KKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKKVREKI-KKPKKYHASR 56
Cdd:PRK14900  998 KKAPAKKAAAKKAAAKKAAAKKKVAKKAPAKKVARKPAAKKAaKKPARKAAGR 1050
COG1754 COG1754
Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];
5-41 1.54e-03

Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];


Pssm-ID: 441360 [Multi-domain]  Cd Length: 892  Bit Score: 40.18  E-value: 1.54e-03
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 45383808   5 KKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKK 41
Cdd:COG1754 851 KKKAAKKAAAKKAAAKKTAAKKAAAKKAAAKKAAAKK 887
PRK13808 PRK13808
adenylate kinase; Provisional
2-124 5.91e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 37.94  E-value: 5.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808    2 AGEKKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKKVREKI--KKPKKYHASRNPVLARGIGKYSRSamyARKALY 79
Cdd:PRK13808 196 AANAKKAAKTPAAKSGAKKASAKAKSAAKKVSKKKAAKTAVSAKKaaKTAAKAAKKAKKTAKKALKKAAKA---VKKAAK 272
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 45383808   80 KRKYTAPETKIEKKKKEKPRATIIKPVGGDKNGGSRVVKVRKMPR 124
Cdd:PRK13808 273 KAAKAAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPK 317
 
Name Accession Description Interval E-value
KOW_RPL6 cd13156
KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as ...
146-298 1.69e-83

KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as an oncogenic. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4.


Pssm-ID: 240520  Cd Length: 152  Bit Score: 247.85  E-value: 1.69e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808 146 HKRRLRASITPGTVLILLTGRHRGKRVVFLKQLGTGLLLVTGPLAVNRVPLRRAHQKFVIATSTKVDISGVKIPkHLTDA 225
Cdd:cd13156   1 KPRKLRSSITPGTVLILLAGRFRGKRVVFLKQLDSGLLLVTGPFKINGVPLRRVNQRYVIATSTKVDISGVKVP-KLNDA 79
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 45383808 226 YFKKKKLRKPKHQEGEIFDTEKEKYEITEQRKTDQKAVDSQILARIKKVPQLRGYLRSTFSLSNGVYPHKLVF 298
Cdd:cd13156  80 YFKRKKKKKKKKKEGEFFEEKKKKYVVSEERKEDQKAVDAALLAAIKKVPLLKGYLKSRFSLRNGDYPHKMKF 152
Ribosomal_L6e pfam01159
Ribosomal protein L6e;
191-298 1.49e-53

Ribosomal protein L6e;


Pssm-ID: 460089  Cd Length: 109  Bit Score: 170.01  E-value: 1.49e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808   191 VNRVPLRRAHQKFVIATSTKVDISGVKIPKHLTDAYFK-KKKLRKPKHQEGEIFDTEKEKYEITEQRKTDQKAVDSQILA 269
Cdd:pfam01159   1 VNGVPLRRVNQRYVIATSTKVDISGVKIPEHINDAYFKkEKKKKKKPKSEEEFFEEKKEKKEVSEQRKADQKAVDKALLA 80
                          90       100
                  ....*....|....*....|....*....
gi 45383808   270 RIKKVPQLRGYLRSTFSLSNGVYPHKLVF 298
Cdd:pfam01159  81 AIKKVPLLKGYLKSSFSLRKGDYPHEMKF 109
Ribosomal_L6e_N pfam03868
Ribosomal protein L6, N-terminal domain;
47-105 5.13e-15

Ribosomal protein L6, N-terminal domain;


Pssm-ID: 427554  Cd Length: 60  Bit Score: 68.12  E-value: 5.13e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45383808    47 KKPKKYHASRNPVLARGIGKYSRSAMYARKALYKRKYTAPETKIEKKKKEKPRATIIKP 105
Cdd:pfam03868   2 PKKGKPHCSRNPVLVRGIGRYSRSAMYSRKAMYKRKYSATKSKIEKKKKEKVLATVTKP 60
valS PRK14900
valyl-tRNA synthetase; Provisional
5-56 4.10e-05

valyl-tRNA synthetase; Provisional


Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 44.98  E-value: 4.10e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 45383808     5 KKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKKVREKI-KKPKKYHASR 56
Cdd:PRK14900  998 KKAPAKKAAAKKAAAKKAAAKKKVAKKAPAKKVARKPAAKKAaKKPARKAAGR 1050
valS PRK14900
valyl-tRNA synthetase; Provisional
2-59 2.36e-04

valyl-tRNA synthetase; Provisional


Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 42.67  E-value: 2.36e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808     2 AGEKKAGEKKAGEKKPAqKKVGEKKPADKKPVEKKAGQKKVREK--IKKPKKYHASRNPV 59
Cdd:PRK14900  986 AATRAAMKKKVAKKAPA-KKAAAKKAAAKKAAAKKKVAKKAPAKkvARKPAAKKAAKKPA 1044
valS PRK14900
valyl-tRNA synthetase; Provisional
5-76 1.21e-03

valyl-tRNA synthetase; Provisional


Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 40.36  E-value: 1.21e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 45383808     5 KKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKKVREKIKKPKKyhASRNPVLARGIGKYSRSAMYARK 76
Cdd:PRK14900  983 KKAAATRAAMKKKVAKKAPAKKAAAKKAAAKKAAAKKKVAKKAPAKK--VARKPAAKKAAKKPARKAAGRKA 1052
COG1754 COG1754
Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];
5-41 1.54e-03

Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];


Pssm-ID: 441360 [Multi-domain]  Cd Length: 892  Bit Score: 40.18  E-value: 1.54e-03
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 45383808   5 KKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKK 41
Cdd:COG1754 851 KKKAAKKAAAKKAAAKKTAAKKAAAKKAAAKKAAAKK 887
PRK13808 PRK13808
adenylate kinase; Provisional
2-124 5.91e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 37.94  E-value: 5.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45383808    2 AGEKKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKKVREKI--KKPKKYHASRNPVLARGIGKYSRSamyARKALY 79
Cdd:PRK13808 196 AANAKKAAKTPAAKSGAKKASAKAKSAAKKVSKKKAAKTAVSAKKaaKTAAKAAKKAKKTAKKALKKAAKA---VKKAAK 272
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 45383808   80 KRKYTAPETKIEKKKKEKPRATIIKPVGGDKNGGSRVVKVRKMPR 124
Cdd:PRK13808 273 KAAKAAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPK 317
COG1754 COG1754
Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];
4-51 7.88e-03

Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];


Pssm-ID: 441360 [Multi-domain]  Cd Length: 892  Bit Score: 37.87  E-value: 7.88e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 45383808   4 EKKAGEKKAGEKKPAQKKVGEKKPADKKPVEKKAGQKKVREKiKKPKK 51
Cdd:COG1754 845 AKGPAKKKKAAKKAAAKKAAAKKTAAKKAAAKKAAAKKAAAK-KAAKK 891
valS PRK14900
valyl-tRNA synthetase; Provisional
2-50 9.80e-03

valyl-tRNA synthetase; Provisional


Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 37.66  E-value: 9.80e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 45383808     2 AGEKKAGEKKAGEKKPAQKKVGEKKPADK----KPVEKKAGQKKVREKIKKPK 50
Cdd:PRK14900 1000 APAKKAAAKKAAAKKAAAKKKVAKKAPAKkvarKPAAKKAAKKPARKAAGRKA 1052
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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