|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00333 |
PTZ00333 |
triosephosphate isomerase; Provisional |
1-246 |
4.63e-132 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 240365 Cd Length: 255 Bit Score: 372.71 E-value: 4.63e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 1 MAPRKFFVGGNWKMNGDKKSLGELIHTLNGAKLSAD-TEVVCGAPSIYLDFARQKLD-AKIGVAAQNCYKVPKGAFTGEI 78
Cdd:PTZ00333 1 MMKRKPFVGGNWKCNGTKASIKELIDSFNKLKFDPNnVDVVVAPPSLHIPLVQEKLKnKNFKISSQNVSLTGSGAFTGEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 79 SPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKD-- 156
Cdd:PTZ00333 81 SAEMLKDLGINWTILGHSERRQYFGETNEIVAQKVKNALENGLKVILCIGETLEEREAGQTSDVLSKQLEAIVKKVSDea 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 157 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASL 236
Cdd:PTZ00333 161 WDNIVIAYEPVWAIGTGKVATPEQAQEVHAFIRKWLAEKVGADVAEATRIIYGGSVNEKNCKELIKQPDIDGFLVGGASL 240
|
250
....*....|
gi 45382061 237 KPEFVDIINA 246
Cdd:PTZ00333 241 KPDFVDIIKS 250
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
6-245 |
2.25e-129 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 365.32 E-value: 2.25e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 6 FFVGGNWKMNGDKKSLGELIHTLNGA-KLSADTEVVCGAPSIYLDFARQKLDA-KIGVAAQNCYKVPKGAFTGEISPAMI 83
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVlKDESGVEVVVAPPFTYLAAVAEALEGsKIKVGAQNVSPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 84 KDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLA 163
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLAGVEDLAPVVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 164 YEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDaVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE-FVD 242
Cdd:cd00311 161 YEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYGE-VAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAEsFLD 239
|
...
gi 45382061 243 IIN 245
Cdd:cd00311 240 IIK 242
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
4-246 |
3.01e-122 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 347.81 E-value: 3.01e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 4 RKFFVGGNWKMNGDKKSLGELIHTL-NGAKLSADTEVVCGAPSIYLDFARQKL-DAKIGVAAQNCYKVPKGAFTGEISPA 81
Cdd:COG0149 2 RKPLIAGNWKMNGTLAEAKALLAALaAALADLADVEVVVCPPFTYLAAVAEALaGSPIALGAQNVHWEDSGAYTGEISAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 82 MIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNV--KDWSK 159
Cdd:COG0149 82 MLKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKAALAGLsaEQAAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 160 VVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE 239
Cdd:COG0149 162 VVIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELYGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDAE 241
|
....*...
gi 45382061 240 -FVDIINA 246
Cdd:COG0149 242 dFLAIVRA 249
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
6-246 |
3.08e-120 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 342.57 E-value: 3.08e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 6 FFVGGNWKMNGDKKSLGELIHTLNGAKL-SADTEVVCGAPSIYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIK 84
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALAdESGVEVVVAPPFTYLSAVAELLGSNIKVGAQNVDPEESGAFTGEISAEMLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 85 DIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDW-SKVVLA 163
Cdd:pfam00121 81 DLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEqKNLVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 164 YEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHvSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE-FVD 242
Cdd:pfam00121 161 YEPVWAIGTGKTATPEQAQEVHAFIRAVLAEL-YKEVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEdFLD 239
|
....
gi 45382061 243 IINA 246
Cdd:pfam00121 240 IINA 243
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
7-239 |
2.64e-62 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 194.25 E-value: 2.64e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 7 FVGGNWKM-NGDKKSLGELIHTLNGAKLSADTEVVCGAPSiYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIKD 85
Cdd:TIGR00419 1 LVIGNWKTyNESRGMRALEVAKIAEEVASEAGVAVAVAPP-FVDLPMIKREVEIPVYAQHVDAVLSGAHTGEISAEMLKD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 86 IGAAWVILGHSERRHVfgESDelIGQKVAHALAEGLGVIACIgekldereagiteKVVFEQTKAIAdnvkdWSKVVLAYE 165
Cdd:TIGR00419 80 IGAKGTLINHSERRMK--LAD--IEKKIARLKELGLTSVVCT-------------NNVLTTAAAAA-----LEPDVVAVE 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45382061 166 PVWAIGTGKTATPQQAQEVHEKLRgwlkshVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE 239
Cdd:TIGR00419 138 PPELIGTGIPVSPAQPEVVHGSVR------AVKEVNESVRVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00333 |
PTZ00333 |
triosephosphate isomerase; Provisional |
1-246 |
4.63e-132 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 240365 Cd Length: 255 Bit Score: 372.71 E-value: 4.63e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 1 MAPRKFFVGGNWKMNGDKKSLGELIHTLNGAKLSAD-TEVVCGAPSIYLDFARQKLD-AKIGVAAQNCYKVPKGAFTGEI 78
Cdd:PTZ00333 1 MMKRKPFVGGNWKCNGTKASIKELIDSFNKLKFDPNnVDVVVAPPSLHIPLVQEKLKnKNFKISSQNVSLTGSGAFTGEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 79 SPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKD-- 156
Cdd:PTZ00333 81 SAEMLKDLGINWTILGHSERRQYFGETNEIVAQKVKNALENGLKVILCIGETLEEREAGQTSDVLSKQLEAIVKKVSDea 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 157 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASL 236
Cdd:PTZ00333 161 WDNIVIAYEPVWAIGTGKVATPEQAQEVHAFIRKWLAEKVGADVAEATRIIYGGSVNEKNCKELIKQPDIDGFLVGGASL 240
|
250
....*....|
gi 45382061 237 KPEFVDIINA 246
Cdd:PTZ00333 241 KPDFVDIIKS 250
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
6-245 |
2.25e-129 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 365.32 E-value: 2.25e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 6 FFVGGNWKMNGDKKSLGELIHTLNGA-KLSADTEVVCGAPSIYLDFARQKLDA-KIGVAAQNCYKVPKGAFTGEISPAMI 83
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVlKDESGVEVVVAPPFTYLAAVAEALEGsKIKVGAQNVSPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 84 KDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLA 163
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLAGVEDLAPVVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 164 YEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDaVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE-FVD 242
Cdd:cd00311 161 YEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYGE-VAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAEsFLD 239
|
...
gi 45382061 243 IIN 245
Cdd:cd00311 240 IIK 242
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
4-246 |
3.01e-122 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 347.81 E-value: 3.01e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 4 RKFFVGGNWKMNGDKKSLGELIHTL-NGAKLSADTEVVCGAPSIYLDFARQKL-DAKIGVAAQNCYKVPKGAFTGEISPA 81
Cdd:COG0149 2 RKPLIAGNWKMNGTLAEAKALLAALaAALADLADVEVVVCPPFTYLAAVAEALaGSPIALGAQNVHWEDSGAYTGEISAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 82 MIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNV--KDWSK 159
Cdd:COG0149 82 MLKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKAALAGLsaEQAAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 160 VVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE 239
Cdd:COG0149 162 VVIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELYGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDAE 241
|
....*...
gi 45382061 240 -FVDIINA 246
Cdd:COG0149 242 dFLAIVRA 249
|
|
| PLN02561 |
PLN02561 |
triosephosphate isomerase |
3-246 |
2.06e-120 |
|
triosephosphate isomerase
Pssm-ID: 178175 Cd Length: 253 Bit Score: 343.34 E-value: 2.06e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 3 PRKFFVGGNWKMNGDKKSLGELIHTLNGAKL-SAD-TEVVCGAPSIYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISP 80
Cdd:PLN02561 2 ARKFFVGGNWKCNGTVEEVKKIVTTLNEAEVpSEDvVEVVVSPPFVFLPLVKSLLRPDFQVAAQNCWVKKGGAFTGEISA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 81 AMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKV 160
Cdd:PLN02561 82 EMLVNLGIPWVILGHSERRALLGESNEFVGDKVAYALSQGLKVIACVGETLEQRESGSTMDVVAAQTKAIADKVSDWANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 161 VLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPEF 240
Cdd:PLN02561 162 VLAYEPVWAIGTGKVATPAQAQEVHDELRKWLHKNVSPEVAATTRIIYGGSVTGANCKELAAQPDVDGFLVGGASLKPEF 241
|
....*.
gi 45382061 241 VDIINA 246
Cdd:PLN02561 242 IDIIKS 247
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
6-246 |
3.08e-120 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 342.57 E-value: 3.08e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 6 FFVGGNWKMNGDKKSLGELIHTLNGAKL-SADTEVVCGAPSIYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIK 84
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALAdESGVEVVVAPPFTYLSAVAELLGSNIKVGAQNVDPEESGAFTGEISAEMLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 85 DIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDW-SKVVLA 163
Cdd:pfam00121 81 DLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEqKNLVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 164 YEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHvSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE-FVD 242
Cdd:pfam00121 161 YEPVWAIGTGKTATPEQAQEVHAFIRAVLAEL-YKEVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEdFLD 239
|
....
gi 45382061 243 IINA 246
Cdd:pfam00121 240 IINA 243
|
|
| tpiA |
PRK00042 |
triosephosphate isomerase; Provisional |
4-246 |
3.28e-115 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 234589 Cd Length: 250 Bit Score: 329.77 E-value: 3.28e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 4 RKFFVGGNWKMNGDKKSLGELIHTLNGA-KLSADTEVVCGAPSIYLDFARQKLDA-KIGVAAQNCYKVPKGAFTGEISPA 81
Cdd:PRK00042 1 RKPIIAGNWKMNKTLAEAKALVEELKAAlPDADGVEVAVAPPFTALASVKEALKGsNIKLGAQNVHPEDSGAFTGEISAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 82 MIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNV--KDWSK 159
Cdd:PRK00042 81 MLKDLGVKYVIIGHSERRQYFGETDELVNKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLEAALAGLsaEQFAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 160 VVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDaVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE 239
Cdd:PRK00042 161 LVIAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYGE-VAEKVRILYGGSVKPDNAAELMAQPDIDGALVGGASLKAE 239
|
....*...
gi 45382061 240 -FVDIINA 246
Cdd:PRK00042 240 dFLAIVKA 247
|
|
| PLN02429 |
PLN02429 |
triosephosphate isomerase |
5-246 |
7.03e-99 |
|
triosephosphate isomerase
Pssm-ID: 166070 Cd Length: 315 Bit Score: 290.92 E-value: 7.03e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 5 KFFVGGNWKMNGDKKSLGELIHTLNGAKLSADTEVVCGAPSIYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIK 84
Cdd:PLN02429 65 KFFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTDRIDISGQNSWVGKGGAFTGEISVEQLK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 85 DIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAY 164
Cdd:PLN02429 145 DLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACIGEKLEEREAGKTFDVCFAQLKAFADAVPSWDNIVVAY 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 165 EPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLK-PEFVDI 243
Cdd:PLN02429 225 EPVWAIGTGKVASPQQAQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKgPEFATI 304
|
...
gi 45382061 244 INA 246
Cdd:PLN02429 305 VNS 307
|
|
| PRK13962 |
PRK13962 |
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional |
2-248 |
2.07e-87 |
|
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional
Pssm-ID: 237572 [Multi-domain] Cd Length: 645 Bit Score: 271.99 E-value: 2.07e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 2 APRKFFVGGNWKMNGDKKSLGELIHTLNGAKLSADTEVVCGAPSIYLDFARQKLD-AKIGVAAQNCYKVPKGAFTGEISP 80
Cdd:PRK13962 395 NPRKPIIAGNWKMNKTPAEAKEFVNELKKYVKDAQAEVVVCPPFTALPSVKEAVDgSNIKLGAQNVFYEEKGAYTGEISG 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 81 AMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNV--KDWS 158
Cdd:PRK13962 475 PMLAEIGVEYVIIGHSERRQYFGETDELVNKKVLAALKAGLTPILCVGETLDERESGITFDVVRLQLKAALNGLsaEQVK 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 159 KVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKP 238
Cdd:PRK13962 555 KVVIAYEPVWAIGTGKVATPEQAQEVHAFIRKLVAELYGEEAARKVRILYGGSVKSENAAGLFNQPDIDGGLVGGASLKA 634
|
250
....*....|.
gi 45382061 239 -EFVDIINAKH 248
Cdd:PRK13962 635 qEFAAIANYFI 645
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
7-239 |
2.64e-62 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 194.25 E-value: 2.64e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 7 FVGGNWKM-NGDKKSLGELIHTLNGAKLSADTEVVCGAPSiYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIKD 85
Cdd:TIGR00419 1 LVIGNWKTyNESRGMRALEVAKIAEEVASEAGVAVAVAPP-FVDLPMIKREVEIPVYAQHVDAVLSGAHTGEISAEMLKD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 86 IGAAWVILGHSERRHVfgESDelIGQKVAHALAEGLGVIACIgekldereagiteKVVFEQTKAIAdnvkdWSKVVLAYE 165
Cdd:TIGR00419 80 IGAKGTLINHSERRMK--LAD--IEKKIARLKELGLTSVVCT-------------NNVLTTAAAAA-----LEPDVVAVE 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45382061 166 PVWAIGTGKTATPQQAQEVHEKLRgwlkshVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE 239
Cdd:TIGR00419 138 PPELIGTGIPVSPAQPEVVHGSVR------AVKEVNESVRVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| PRK14565 |
PRK14565 |
triosephosphate isomerase; Provisional |
6-244 |
2.71e-53 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 237758 Cd Length: 237 Bit Score: 172.25 E-value: 2.71e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 6 FFVGGNWKMNGDKKSLGELIHTLNgAKLS---ADTEVVCGAPSIYLDfARQKLDAKIGVAAQNCYKVPKGAFTGEISPAM 82
Cdd:PRK14565 3 FLIVANWKMNGDFSLFSSFLKELS-NKLAnneITLKLVICPPFTAMS-SFVECNPNIKLGAQNCFYGSSGGYTGEISAKM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 83 IKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKaiaDNVKDWSKVVL 162
Cdd:PRK14565 81 LKECGCSYVILGHSERRSTFHETDSDIRLKAESAIESGLIPIICVGETLEDRENGMTKDVLLEQCS---NCLPKHGEFII 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 163 AYEPVWAIGTGKTATPQQAQEVHEKLRgwlkSHVSdavaqSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE-FV 241
Cdd:PRK14565 158 AYEPVWAIGGSTIPSNDAIAEAFEIIR----SYDS-----KSHIIYGGSVNQENIRDLKSINQLSGVLVGSASLDVDsFC 228
|
...
gi 45382061 242 DII 244
Cdd:PRK14565 229 KII 231
|
|
| PRK15492 |
PRK15492 |
triosephosphate isomerase; Provisional |
4-232 |
1.59e-38 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 185389 Cd Length: 260 Bit Score: 134.73 E-value: 1.59e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 4 RKFFVGGNWKM---NGDK----KSLGELIHTLNGAKlsaDTEVVCGAPSIYLDFARQKL-----DAKIGVAAQNCYKVPK 71
Cdd:PRK15492 2 KKIYFGTNLKMykgIADAtdflAKLSELADDIPADK---DIELFVIPSFTAIQDAIAATlaiphDHPIIIGAQNMNPNDN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 72 GAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKA-- 149
Cdd:PRK15492 79 GQFTGDISPLMLKEIGTQLVMIGHSERRHKFGETDQEENAKVLAALKHDFTTLLCVGETLEQKNYGISDEILRTQLKIgl 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 150 IADNVKDWSKVVLAYEPVWAIGT-GKTATPQQAQEVHEKLRGWLKSHVSDAvAQSTRIIYGGSVTGGNCKELASQHDVDG 228
Cdd:PRK15492 159 HGINPDQLAKLRIAYEPVWAIGEaGIPASADYADEKHAVIKQCLIELFGDA-GDDIPVFYGGSVNAENANELFGQPHIDG 237
|
....
gi 45382061 229 FLVG 232
Cdd:PRK15492 238 LFIG 241
|
|
| PRK14905 |
PRK14905 |
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ... |
58-232 |
7.33e-38 |
|
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional
Pssm-ID: 184898 [Multi-domain] Cd Length: 355 Bit Score: 135.54 E-value: 7.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 58 KIGVAAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAG 137
Cdd:PRK14905 66 KIKIGAQNMNAKDKGQFTGEISPLMLKELGIELVMIGHSERRHVLKETDQEENEKVLAALKHGFITLLCIGETLEQKNYN 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 138 ITEKVVFEQTKAIADNV--KDWSKVVLAYEPVWAIGTGKT-ATPQQAQEVHEKLRGWLKSHVSDAvAQSTRIIYGGSVTG 214
Cdd:PRK14905 146 ISDEVLRTQLKIGLHGVsaEQLPHLFIAYEPVWAIGEGGIpASAEYADEKHAIIKQCLFELFAEE-SKKIPVLYGGSVNL 224
|
170
....*....|....*...
gi 45382061 215 GNCKELASQHDVDGFLVG 232
Cdd:PRK14905 225 ENANELIMKPHIDGLFIG 242
|
|
| PRK04302 |
PRK04302 |
triosephosphate isomerase; Provisional |
31-237 |
1.46e-09 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 235274 Cd Length: 223 Bit Score: 56.41 E-value: 1.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 31 AKLSADTEVVCG-APSiYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGEsdelI 109
Cdd:PRK04302 29 EKVSKETGVRIAvAPQ-ALDIRRVAEEVDIPVYAQHVDPVEPGSHTGHILPEAVKDAGAVGTLINHSERRLTLAD----I 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45382061 110 GQKVAHALAEGLGVIACigekldereagiTEKVvfEQTKAIADNVKDWskvvLAYEPVWAIGTGK---TATPqqaqEVhe 186
Cdd:PRK04302 104 EAVVERAKKLGLESVVC------------VNNP--ETSAAAAALGPDY----VAVEPPELIGTGIpvsKAKP----EV-- 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 45382061 187 klrgwlkshVSDAVA------QSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLK 237
Cdd:PRK04302 160 ---------VEDAVEavkkvnPDVKVLCGAGISTGEDVKAALELGADGVLLASGVVK 207
|
|
| |
