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Conserved domains on  [gi|45552929|ref|NP_995991|]
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phosphatidylinositol glycan anchor biosynthesis class B, isoform B [Drosophila melanogaster]

Protein Classification

Glyco_transf_22 domain-containing protein( domain architecture ID 10511211)

Glyco_transf_22 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
5-396 9.20e-130

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


:

Pssm-ID: 281842  Cd Length: 414  Bit Score: 384.41  E-value: 9.20e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929     5 YVFLLILAVRLASVFVVQTYyVPDEYWQSLEVAHKLTFGYGYLTWEW--VQGIRSYVYPLLIAGLYKILALLQLDSAHLL 82
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWspKYGIRSYLYPLLFALPYYLLARLFGDSKYLV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929    83 VVLPRIVQALLSAYSDYRFFVWTGK------RKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGES----- 151
Cdd:pfam03901  80 FYAPRLLLGLFSALCDYYLYRAVCRkygleiARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTsvsny 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   152 ---TAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVA----GLGIAIDTYWHGQLIVTPYEF 224
Cdd:pfam03901 160 kylKAVLLIAALAILGRPTSALLWLPLVLYLLLRLRGKRLKLFLFLAISLGLLVAllvlGAVILIDSYFYGRFVFTPLNF 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   225 LKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKseKYPVSKQLLITIFLTLVVLSAVEHKEFRFVS 304
Cdd:pfam03901 240 LKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLR--KVSRLSQLLAPILIWLFIYSLQPHKEERFLY 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   305 PLLPLCLYVITDALSRWS--IRASSTMLWtTALVILVGNVMPAWYLSTVHQKGPI----ELMPKLREIAREYRDEREHQA 378
Cdd:pfam03901 318 PVYPLILLSAAIALTRLSrrSWKVRKKLS-LLFLLLFFNVSLARLFGLVHQYGAPlavyDVMSFLNETPRENRNPAGPPV 396
                         410
                  ....*....|....*...
gi 45552929   379 NILFLMPCHSTPYYSHIH 396
Cdd:pfam03901 397 NVCIGMECYSTPSSFFLH 414
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
5-396 9.20e-130

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 384.41  E-value: 9.20e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929     5 YVFLLILAVRLASVFVVQTYyVPDEYWQSLEVAHKLTFGYGYLTWEW--VQGIRSYVYPLLIAGLYKILALLQLDSAHLL 82
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWspKYGIRSYLYPLLFALPYYLLARLFGDSKYLV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929    83 VVLPRIVQALLSAYSDYRFFVWTGK------RKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGES----- 151
Cdd:pfam03901  80 FYAPRLLLGLFSALCDYYLYRAVCRkygleiARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTsvsny 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   152 ---TAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVA----GLGIAIDTYWHGQLIVTPYEF 224
Cdd:pfam03901 160 kylKAVLLIAALAILGRPTSALLWLPLVLYLLLRLRGKRLKLFLFLAISLGLLVAllvlGAVILIDSYFYGRFVFTPLNF 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   225 LKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKseKYPVSKQLLITIFLTLVVLSAVEHKEFRFVS 304
Cdd:pfam03901 240 LKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLR--KVSRLSQLLAPILIWLFIYSLQPHKEERFLY 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   305 PLLPLCLYVITDALSRWS--IRASSTMLWtTALVILVGNVMPAWYLSTVHQKGPI----ELMPKLREIAREYRDEREHQA 378
Cdd:pfam03901 318 PVYPLILLSAAIALTRLSrrSWKVRKKLS-LLFLLLFFNVSLARLFGLVHQYGAPlavyDVMSFLNETPRENRNPAGPPV 396
                         410
                  ....*....|....*...
gi 45552929   379 NILFLMPCHSTPYYSHIH 396
Cdd:pfam03901 397 NVCIGMECYSTPSSFFLH 414
PLN02816 PLN02816
mannosyltransferase
6-486 5.45e-89

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 283.85  E-value: 5.45e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929    6 VFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAGLYKILALLQLDSAHLLVVL 85
Cdd:PLN02816  41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   86 PRIVQALLSAYSDYRFF-----VWTGK-RKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTA------ 153
Cdd:PLN02816 121 PRLMQSIFSAIGDLYLYklsdaLYGGNvATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIdypvnr 200
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  154 --YLWPAAICCFLRPTAAVIWLPLSLYHLRRSrQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFN 231
Cdd:PLN02816 201 kwGLVIAALACAIRPTSAVIWLYVGMLELFLT-PNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLS 279
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  232 NIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETvkksekypVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCL 311
Cdd:PLN02816 280 SGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKS--------KNQKLSALILWVLAIYSILGHKEFRFVLPVLPIAL 351
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  312 YVITDALSRWSIRASST---------------MLWTTAL-----VILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYR 371
Cdd:PLN02816 352 IFSGYAFAQMEVSGSSSsssvtkkkqvprqnhTKWSPKLrlsvyFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGR 431
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  372 DErehqaNILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQykDEADRFFEDPVHWINSHipMHPLTALPTHVVLFD 451
Cdd:PLN02816 432 VK-----SILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGEL--DESDQFLVNPLGFASEL--ARNWSEPPSHIVLFA 502
                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 45552929  452 PLAENISVFL--RNYRLLHRIEHAENRQSRTGRSILV 486
Cdd:PLN02816 503 SEETKLRDFMiqHSFKEVRRFFHAHFKVDRDLQSSVV 539
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
5-396 9.20e-130

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 384.41  E-value: 9.20e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929     5 YVFLLILAVRLASVFVVQTYyVPDEYWQSLEVAHKLTFGYGYLTWEW--VQGIRSYVYPLLIAGLYKILALLQLDSAHLL 82
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWspKYGIRSYLYPLLFALPYYLLARLFGDSKYLV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929    83 VVLPRIVQALLSAYSDYRFFVWTGK------RKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGES----- 151
Cdd:pfam03901  80 FYAPRLLLGLFSALCDYYLYRAVCRkygleiARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTsvsny 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   152 ---TAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVA----GLGIAIDTYWHGQLIVTPYEF 224
Cdd:pfam03901 160 kylKAVLLIAALAILGRPTSALLWLPLVLYLLLRLRGKRLKLFLFLAISLGLLVAllvlGAVILIDSYFYGRFVFTPLNF 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   225 LKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKseKYPVSKQLLITIFLTLVVLSAVEHKEFRFVS 304
Cdd:pfam03901 240 LKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLR--KVSRLSQLLAPILIWLFIYSLQPHKEERFLY 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   305 PLLPLCLYVITDALSRWS--IRASSTMLWtTALVILVGNVMPAWYLSTVHQKGPI----ELMPKLREIAREYRDEREHQA 378
Cdd:pfam03901 318 PVYPLILLSAAIALTRLSrrSWKVRKKLS-LLFLLLFFNVSLARLFGLVHQYGAPlavyDVMSFLNETPRENRNPAGPPV 396
                         410
                  ....*....|....*...
gi 45552929   379 NILFLMPCHSTPYYSHIH 396
Cdd:pfam03901 397 NVCIGMECYSTPSSFFLH 414
PLN02816 PLN02816
mannosyltransferase
6-486 5.45e-89

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 283.85  E-value: 5.45e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929    6 VFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAGLYKILALLQLDSAHLLVVL 85
Cdd:PLN02816  41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929   86 PRIVQALLSAYSDYRFF-----VWTGK-RKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTA------ 153
Cdd:PLN02816 121 PRLMQSIFSAIGDLYLYklsdaLYGGNvATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIdypvnr 200
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  154 --YLWPAAICCFLRPTAAVIWLPLSLYHLRRSrQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFN 231
Cdd:PLN02816 201 kwGLVIAALACAIRPTSAVIWLYVGMLELFLT-PNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLS 279
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  232 NIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETvkksekypVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCL 311
Cdd:PLN02816 280 SGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKS--------KNQKLSALILWVLAIYSILGHKEFRFVLPVLPIAL 351
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  312 YVITDALSRWSIRASST---------------MLWTTAL-----VILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYR 371
Cdd:PLN02816 352 IFSGYAFAQMEVSGSSSsssvtkkkqvprqnhTKWSPKLrlsvyFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGR 431
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45552929  372 DErehqaNILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQykDEADRFFEDPVHWINSHipMHPLTALPTHVVLFD 451
Cdd:PLN02816 432 VK-----SILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGEL--DESDQFLVNPLGFASEL--ARNWSEPPSHIVLFA 502
                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 45552929  452 PLAENISVFL--RNYRLLHRIEHAENRQSRTGRSILV 486
Cdd:PLN02816 503 SEETKLRDFMiqHSFKEVRRFFHAHFKVDRDLQSSVV 539
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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