|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
34-346 |
2.88e-126 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 364.96 E-value: 2.88e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 34 PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELYGpDLYRQRVLELNASDERGIQV 113
Cdd:PRK00440 6 IWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYG-EDWRENFLELNASDERGIDV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 114 VREKVKRFAQltvagTRPDGKTcpPFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFR 193
Cdd:PRK00440 85 IRNKIKEFAR-----TAPVGGA--PFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 194 FKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLNseREITEQTIIEIAGVVPPKVIQSLL 273
Cdd:PRK00440 158 FSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATG--KEVTEEAVYKITGTARPEEIREMI 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 52317098 274 HICYKGTFEKLEVAVKD-MIDQGYAATNLLNQLHDVIIEEQLSDKQKSVITEKMAEVDKCLADGADEYLQLLSL 346
Cdd:PRK00440 236 ELALNGDFTEAREKLRDlMIDYGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEAL 309
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
33-348 |
1.95e-90 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 273.91 E-value: 1.95e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 33 VPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELYGPDlYRQRVLELNASDERGIQ 112
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGPN-YKEAVLELNASDDRGID 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 113 VVREKVKRFAQLTVagTRPDGKTcppfKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKF 192
Cdd:PLN03025 80 VVRNKIKMFAQKKV--TLPPGRH----KIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 193 RFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQsgARLNSEREITEQTIIEIAGVVPPKVIQSL 272
Cdd:PLN03025 154 RFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQ--ATHSGFGFVNQENVFKVCDQPHPLHVKNI 231
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 52317098 273 LHICYKGTFEKLEVAVKDMIDQGYAATNLLNQLHDVIIEEQLSDKQKsviTEKMAEVDKC---LADGADEYLQLLSLCS 348
Cdd:PLN03025 232 VRNCLKGKFDDACDGLKQLYDLGYSPTDIITTLFRVVKNYDMPEFLK---LEYLREIGFAhmrICDGVGSLLQLSGLLA 307
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
35-343 |
2.24e-70 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 223.33 E-value: 2.24e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 35 WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELYGpDLYRQRVLELNASD--ERGIQ 112
Cdd:PRK12402 5 WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYG-DPWENNFTEFNVADffDQGKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 113 VVREKvKRFAQLTV--------------------AGTRP-DGktcpPFKIIILDEADSMTSAAQAALRRTMEKESRTTRF 171
Cdd:PRK12402 84 YLVED-PRFAHFLGtdkrirsskidnfkhvlkeyASYRPlSA----DYKTILLDNAEALREDAQQALRRIMEQYSRTCRF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 172 CLICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARlnSERE 251
Cdd:PRK12402 159 IIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAAL--AAGE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 252 ITEQTIIEIAGVVPPK-VIQSLLHICYKGTFEKLEVAVKD-MIDQGYAATNLLNQLHDVIIeEQLSDKQKSVITEKMAEV 329
Cdd:PRK12402 237 ITMEAAYEALGDVGTDeVIESLLDAAEAGDFTDARKTLDDlLIDEGLSGGEVLEELLRVAR-SRYRGDNLARLHRLAADA 315
|
330
....*....|....
gi 52317098 330 DKCLADGADEYLQL 343
Cdd:PRK12402 316 DARLTDGANDRIQL 329
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
80-346 |
6.33e-64 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 217.78 E-value: 6.33e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 80 TSTILAAARELYGPDlYRQRVLELNASDERGIQVVREKVKRFAQltvagTRPDGKTcpPFKIIILDEADSMTSAAQAALR 159
Cdd:PRK04132 580 TTAALALARELFGEN-WRHNFLELNASDERGINVIREKVKEFAR-----TKPIGGA--SFKIIFLDEADALTQDAQQALR 651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 160 RTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITF 239
Cdd:PRK04132 652 RTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINI 731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 240 LQSGARLNseREITEQTIIEIAGVVPPKVIQSLLHICYKGTFEKLEVAVKD-MIDQGYAATNLLNQLHDVIIEEQLSDKQ 318
Cdd:PRK04132 732 LQAAAALD--DKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREiLLKQGLSGEDVLVQMHREVFNLPIDEPK 809
|
250 260
....*....|....*....|....*...
gi 52317098 319 KSVITEKMAEVDKCLADGADEYLQLLSL 346
Cdd:PRK04132 810 KVELADKIGEYNFRLVEGANEMIQLEAL 837
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
50-346 |
3.75e-49 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 166.69 E-value: 3.75e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 50 QEEVVAVLKKSLEGADLP-NLLFYGPPGTGKTSTILAAARELYG----------------------PDLYrqrvlELNA- 105
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPhALLLHGPPGIGKTTLALALARDLLCenpeggkacgqchsrlmaagnhPDLL-----ELNPe 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 106 --SDERGIQVVREkVKRFAQLTVAGTRpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIE 183
Cdd:COG0470 76 ekSDQIGIDQIRE-LGEFLSLTPLEGG--------RKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 184 PLTSRCSKFRFKPLAndvqQERILEICRKENLkyTTEGVDALVRVSEGDLRKAITFLQSGArlnsereiTEQTIIEIAGV 263
Cdd:COG0470 147 TIRSRCQVIRFRPPS----EEEALAWLREEGV--DEDALEAILRLAGGDPRAAINLLQALA--------GRKELLEDLAA 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 264 VPPKviqsllhicyKGTFEKLEVAVKDMIDQGYAAtnLLNQLHDVIIeEQLSDKQKSVITEKMAEVDKCLADGADEYLQL 343
Cdd:COG0470 213 LLSR----------DRALELLDALLKAEALELLDW--LLKWLLDNLP-LEYAGEDLARAYEALSEADRRLGRYANDRLLL 279
|
...
gi 52317098 344 LSL 346
Cdd:COG0470 280 EAL 282
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
35-351 |
1.70e-38 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 139.35 E-value: 1.70e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 35 WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGP-PGTGKTSTILAAARELyGPDlyrqrVLELNASDERgIQV 113
Cdd:PHA02544 11 WEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPsPGTGKTTVAKALCNEV-GAE-----VLFVNGSDCR-IDF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 114 VREKVKRFAQlTVAgtrpdgkTCPPFKIIILDEAD-SMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKF 192
Cdd:PHA02544 84 VRNRLTRFAS-TVS-------LTGGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 193 RFKPLANDVQQE-------RILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGArlnSEREITEQTIIEIAGVVP 265
Cdd:PHA02544 156 DFGVPTKEEQIEmmkqmivRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQRYA---STGKIDAGILSEVTNSDI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 266 PKVIQSLLHICYKGtfeklevaVKDMIDQgYAAT--NLLNQLHDVIIeEQLSDKQKSVITEKMAEVDKCLADGADEYLQL 343
Cdd:PHA02544 233 DDVVEALKAKDFKA--------VRALAPN-YANDyaSFVGKLYDELY-PQVTPPSIIRLIEIIGENNQYHGFAADQEIHL 302
|
....*...
gi 52317098 344 LSLCSVIM 351
Cdd:PHA02544 303 LYLLTQLM 310
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
32-262 |
7.22e-33 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 127.73 E-value: 7.22e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 32 AVPWVEKYRPKCVDEVAFQEEVVAVLKKSLE----GADLPNLLFYGPPGTGKTSTILAAARElYGPDlyrqrVLELNASD 107
Cdd:PRK04195 1 MMPWVEKYRPKTLSDVVGNEKAKEQLREWIEswlkGKPKKALLLYGPPGVGKTSLAHALAND-YGWE-----VIELNASD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 108 ERGiqvvREKVKRFAQltvAGTRPDGKTCPPFKIIILDEADSM-----TSAAQAALRrtMEKESRTTrFCLICN-YVSRI 181
Cdd:PRK04195 75 QRT----ADVIERVAG---EAATSGSLFGARRKLILLDEVDGIhgnedRGGARAILE--LIKKAKQP-IILTANdPYDPS 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 182 IEPLTSRCSKFRFKPL-ANDVqQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGArlNSEREITEQTIIEI 260
Cdd:PRK04195 145 LRELRNACLMIEFKRLsTRSI-VPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIA--EGYGKLTLEDVKTL 221
|
..
gi 52317098 261 AG 262
Cdd:PRK04195 222 GR 223
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
33-307 |
1.32e-27 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 112.99 E-value: 1.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 33 VPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA------------------RELY 91
Cdd:PRK14953 4 IPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHaYIFAGPRGTGKTTIarILAKVlnclnpqegepcgkcencVEID 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 92 G---PDLYrqrvlELNASDERGIQVVREkvkrfAQLTVAGTRPDGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRT 168
Cdd:PRK14953 84 KgsfPDLI-----EIDAASNRGIDDIRA-----LRDAVSYTPIKGK----YKVYIIDEAHMLTKEAFNALLKTLEEPPPR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 169 TRFCLICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSgARLNS 248
Cdd:PRK14953 150 TIFILCTTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQ-ASTYG 228
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 52317098 249 EREITEQTIIEIAGVVPPKVIQSLLHICykgtfekLEVAVKDMIdqgyaatNLLNQLHD 307
Cdd:PRK14953 229 EGKVTIKVVEEFLGIVSQESVRKFLNLL-------LESDVDEAI-------KFLRTLEE 273
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
38-312 |
2.20e-25 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 106.39 E-value: 2.20e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA-----RELYGP-----------DLYRQ 98
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHaYIFAGPRGTGKTTVarILAKSlncenRKGVEPcnecracrsidEGTFM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 RVLELNASDERGIQVVReKVKRfaqlTVAGTRPDGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYV 178
Cdd:PRK14962 87 DVIELDAASNRGIDEIR-KIRD----AVGYRPMEGK----YKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 179 SRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnSEREITEQTII 258
Cdd:PRK14962 158 EKVPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKF-SEGKITLETVH 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 52317098 259 EIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQLHDVIIEE 312
Cdd:PRK14962 237 EALGLIPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLVED 290
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
37-262 |
1.39e-24 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 103.63 E-value: 1.39e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 37 EKYRPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELygpdlyRQRVLELNASDErGIQV 113
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLGpgkPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGAT------DAPFEALSAVTS-GVKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 114 VREKVKRFAQLTVAGTRPdgktcppfkIIILDEADSMTSAAQAALRRTMEKESRTtrfcLIC----N-YVSrIIEPLTSR 188
Cdd:PRK13342 77 LREVIEEARQRRSAGRRT---------ILFIDEIHRFNKAQQDALLPHVEDGTIT----LIGatteNpSFE-VNPALLSR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 52317098 189 CSKFRFKPL-ANDVQQ--ERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGArlNSEREITEQTIIEIAG 262
Cdd:PRK13342 143 AQVFELKPLsEEDIEQllKRALEDKERGLVELDDEALDALARLANGDARRALNLLELAA--LGVDSITLELLEEALQ 217
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
264-348 |
2.69e-24 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 94.85 E-value: 2.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 264 VPPKVIQSLLHICYKGTFEK-LEVAVKDMIDQGYAATNLLNQLHDVIIEEQLSDKQKSVITEKMAEVDKCLADGADEYLQ 342
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEaYKKVRELLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*.
gi 52317098 343 LLSLCS 348
Cdd:pfam08542 81 LSALLA 86
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
41-328 |
3.03e-24 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 101.42 E-value: 3.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 41 PKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA---------------------RELYGPDly 96
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLarILAKAlncengptgepcgecescraiAAGSHPD-- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 97 rqrVLEL--NASdERGIQVVREKVKRFAQLTVAGtrpdgktcpPFKIIILDEADSMTSAAQAALRRTMEkE--SRTTrFC 172
Cdd:COG2812 84 ---VIEIdaEAS-NIGVDDIRELIEKVSYAPVEG---------RYKVYIIDEAHMLTTEAFNALLKTLE-EppPHVV-FI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 173 LICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSgARLNSEREI 252
Cdd:COG2812 149 LATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ-AIAFGLLDR 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 253 TEQTIieiagvvppkviqSLLHICYKGTFEKLEVAVKDMIDQGY----AATNLLNQLHDVIIeEQLSDKQKSVITEKMAE 328
Cdd:COG2812 228 RELLL-------------DLLEALLAGDVAALLALAEELAKRGRdlkrFLDDLLSLLRDLLL-LKLGPDAELLVNEDERE 293
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
50-196 |
8.03e-23 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 92.98 E-value: 8.03e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 50 QEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELYGPDLyrqRVLELNASDERGIQVVREKVKRFAQLTVAGT 129
Cdd:cd00009 3 QEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGA---PFLYLNASDLLEGLVVAELFGHFLVRLLFEL 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52317098 130 RPDGKTCppfkIIILDEADSMTSAAQAALRRTME------KESRTTRFCLICNYVS--RIIEPLTSRC-SKFRFKP 196
Cdd:cd00009 80 AEKAKPG----VLFIDEIDSLSRGAQNALLRVLEtlndlrIDRENVRVIGATNRPLlgDLDRALYDRLdIRIVIPL 151
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
35-310 |
9.91e-22 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 96.43 E-value: 9.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 35 WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA------RELYGP------------ 93
Cdd:PRK07133 8 LYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHaYLFSGPRGTGKTSVakIFANAlncshkTDLLEPcqecienvnnsl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 94 DlyrqrVLELNASDERGIQVVR---EKVKRFAQLTvagtrpdgktcpPFKIIILDEADSMTSAAQAALRRTMEKESRTTR 170
Cdd:PRK07133 88 D-----IIEMDAASNNGVDEIReliENVKNLPTQS------------KYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 171 FCLICNYVSRIiePLT--SRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnS 248
Cdd:PRK07133 151 FILATTEVHKI--PLTilSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIF-G 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 52317098 249 EREITEQTIIEIAGVVP-PKVIQSLLHICYKGTFEKLEVAvKDMIDQG----YAATNLLNQLHDVII 310
Cdd:PRK07133 228 NNKITLKNVEELFGLVSnENLINLLNLLYSKDIKEVLNIL-NQIKEQGidpeLLLISLINLVKEFII 293
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
38-241 |
5.44e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 90.78 E-value: 5.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAARELYGPDLYR----------------Q 98
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHaYIFFGPRGVGKTTIarILAKRLNCENPIGNEpcnectscleitkgisS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 RVLELNASDERGIQVVRE---KVKrFAQLtvagtrpDGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLIC 175
Cdd:PRK14956 91 DVLEIDAASNRGIENIRElrdNVK-FAPM-------GGK----YKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILAT 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52317098 176 NYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQ 241
Cdd:PRK14956 159 TEFHKIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFME 224
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
69-197 |
1.70e-18 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 80.72 E-value: 1.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 69 LLFYGPPGTGKTSTILAAARELYGPdlyrqrVLELNASDERGIQvVREKVKRFAQ-LTVAgtrpdgKTCPPfKIIILDEA 147
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGAP------FIEISGSELVSKY-VGESEKRLRElFEAA------KKLAP-CVIFIDEI 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 52317098 148 DSMTSA-----------AQAALRRTMEKESRTTR---FCLICNYVSRIIEPLTSRCSKFRFKPL 197
Cdd:pfam00004 67 DALAGSrgsggdsesrrVVNQLLTELDGFTSSNSkviVIAATNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
37-330 |
2.26e-18 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 86.44 E-value: 2.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 37 EKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTS--TILAAARELYGPD--------------LYRQR 99
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSiaKIFAKAINCLNPKdgdccnscsvcesiNTNQS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 100 V--LELNASDERGIQVVREKVKRFAQLtvagtrpdgKTCPPFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNY 177
Cdd:PRK05896 88 VdiVELDAASNNGVDEIRNIIDNINYL---------PTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 178 VSRIiePLT--SRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARlNSEREITEQ 255
Cdd:PRK05896 159 FQKI--PLTiiSRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLST-FKNSEIDIE 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 52317098 256 TIIEIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQLHDVIIEEQLSDKQKSVITEKMAEVD 330
Cdd:PRK05896 236 DINKTFGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVYQKTKNINLLKKLSKE 310
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
37-305 |
7.05e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 84.51 E-value: 7.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 37 EKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAARELYGPD-----------LYRQ---- 98
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHaYLFSGPRGVGKTTTarLIAMAVNCSGEDpkpcgecesclAVRRgahp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 RVLELNASDERGIQVVREKVKRFAQLTVAGTRpdgktcppfKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYV 178
Cdd:PRK14963 86 DVLEIDAASNNSVEDVRDLREKVLLAPLRGGR---------KVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 179 SRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSgaRLNSEREITEQTII 258
Cdd:PRK14963 157 EKMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLER--LLALGTPVTRKQVE 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 52317098 259 EIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQL 305
Cdd:PRK14963 235 EALGLPPQERLRGIAAALAQGDAAEALSGAAQLYRDGFAARTLVEGL 281
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
38-310 |
9.00e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 83.39 E-value: 9.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELYGPDL------YRQRVLELNASDERG 110
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPGYddpnedFSFNIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 111 IQVVREKVK--RFAQLTvagtrpdGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSR 188
Cdd:PRK14970 90 VDDIRNLIDqvRIPPQT-------GK----YKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 189 CSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnSEREITEQTIIEIAGVVPPKV 268
Cdd:PRK14970 159 CQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTF-CGKNITRQAVTENLNILDYDT 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 52317098 269 IQSLLHICYKGTFEKLEVAVKDMIDQGYAATN----LLNQLHDVII 310
Cdd:PRK14970 238 YINVTDLILENKIPELLLAFNEILRKGFDGHHfiagLASHFRDLMV 283
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
38-305 |
1.41e-17 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 83.93 E-value: 1.41e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELY---GP-----DLYRQRV-------- 100
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHaYLFSGLRGSGKTSSARIFARALVceqGPsstpcDTCIQCQsalenrhi 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 101 --LELNASDERGIQVVREKVKR------FAQltvagtrpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFC 172
Cdd:PRK08451 87 diIEMDAASNRGIDDIRELIEQtkykpsMAR---------------FKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 173 LICNyvsriiEPLT------SRCSKFRFKPLA-NDVQQ--ERILEicrKENLKYTTEGVDALVRVSEGDLRKAITFLQSg 243
Cdd:PRK08451 152 LATT------DPLKlpatilSRTQHFRFKQIPqNSIIShlKTILE---KEGVSYEPEALEILARSGNGSLRDTLTLLDQ- 221
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 52317098 244 ARLNSEREITEQTIIEIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMidQGYAATNLLNQL 305
Cdd:PRK08451 222 AIIYCKNAITESKVADMLGLLDPSKLEDFFQAILNQDKEKLFELLKEL--EDYEAEMVLDEM 281
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
40-262 |
1.83e-16 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 80.10 E-value: 1.83e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 40 RPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTS--TILAAA--RELYgpdlyrqrvlELNASDErGIQ 112
Cdd:COG2256 20 RPRTLDEVVGQEHLLGpgkPLRRAIEAGRLSSMILWGPPGTGKTTlaRLIANAtdAEFV----------ALSAVTS-GVK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 113 VVREKVKRFAQLTVAGTRPdgktcppfkIIILDEADSMTSAAQAALRRTMEKESRTtrfcLIC----N-YVSrIIEPLTS 187
Cdd:COG2256 89 DIREVIEEARERRAYGRRT---------ILFVDEIHRFNKAQQDALLPHVEDGTIT----LIGatteNpSFE-VNSALLS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 188 RCSKFRFKPL-ANDVQQ--ERILEICRK----ENLKYTTEGVDALVRVSEGDLRKAITFLQSGARL---NSEREITEQTI 257
Cdd:COG2256 155 RCRVFVLKPLsEEDLEQllERALADDERglggYKLELDDEALEALARLADGDARRALNALELAVLSappDGVIEITLELV 234
|
....*
gi 52317098 258 IEIAG 262
Cdd:COG2256 235 EEALQ 239
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
38-286 |
1.18e-15 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 77.89 E-value: 1.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAAREL---YGPDLY---------------RQ 98
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANaYIFSGPRGVGKTSSARAFARCLncvNGPTPMpcgecsscksidndnSL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 RVLELNASDERGIQVVREkVKRFAQLTVAGTRpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYV 178
Cdd:PRK06647 89 DVIEIDGASNTSVQDVRQ-IKEEIMFPPASSR--------YRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 179 SRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnSEREITEQTII 258
Cdd:PRK06647 160 HKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSF-SDSDITLEQIR 238
|
250 260
....*....|....*....|....*....
gi 52317098 259 EIAGVVPPKVIQSL-LHICYKGTFEKLEV 286
Cdd:PRK06647 239 SKMGLTGDEFLEKLaSSILNEDAKELLCV 267
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
30-270 |
1.42e-15 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 77.79 E-value: 1.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 30 QRAVPWVEKYRPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTS--TILAaarelygpDLYRQRVLELN 104
Cdd:PRK13341 13 QSEAPLADRLRPRTLEEFVGQDHILGegrLLRRAIKADRVGSLILYGPPGVGKTTlaRIIA--------NHTRAHFSSLN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 105 ASdERGIQVVREKVKRfAQLTVAgtRPDGKTcppfkIIILDEADSMTSAAQAALRRTMEKESRTtrfcLIC----NYVSR 180
Cdd:PRK13341 85 AV-LAGVKDLRAEVDR-AKERLE--RHGKRT-----ILFIDEVHRFNKAQQDALLPWVENGTIT----LIGatteNPYFE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 181 IIEPLTSRCSKFRFKPL-ANDVQQ--ERILEICR----KENLKYTTEGVDALVRVSEGDLRKAITFLQsgarLNSER-EI 252
Cdd:PRK13341 152 VNKALVSRSRLFRLKSLsDEDLHQllKRALQDKErgygDRKVDLEPEAEKHLVDVANGDARSLLNALE----LAVEStPP 227
|
250
....*....|....*...
gi 52317098 253 TEQTIIEIAGVVPPKVIQ 270
Cdd:PRK13341 228 DEDGLIDITLAIAEESIQ 245
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
38-273 |
2.37e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 74.05 E-value: 2.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILA---------------------AARELYGP 93
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCarIISlclncsngptsdpcgtchnciSIKNSNHP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 94 DlyrqrVLELNASDERGIQVVREKVKRFAQLTVAGTrpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCL 173
Cdd:PRK14964 86 D-----VIEIDAASNTSVDDIKVILENSCYLPISSK---------FKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFIL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 174 ICNYVSRIiePLT--SRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAItFLQSGARLNSERE 251
Cdd:PRK14964 152 ATTEVKKI--PVTiiSRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNAL-FLLEQAAIYSNNK 228
|
250 260
....*....|....*....|..
gi 52317098 252 ITEQTIIEIAGVVPPKVIQSLL 273
Cdd:PRK14964 229 ISEKSVRDLLGCVDKHILEDLV 250
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
204-261 |
4.48e-14 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 66.01 E-value: 4.48e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 52317098 204 ERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLNseREITEQTIIEIA 261
Cdd:cd18140 8 KRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGG--GVITEEDVYEVA 63
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
34-250 |
9.86e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 72.41 E-value: 9.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 34 PWVEKYRPKCVDEVAFQEEVVAVLKKSL-EGADLPNLLFYGPPGTGKTSTILAAAREL---YGP--------DLYRQ--- 98
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQETVKAILSRAAqENRVAPAYLFSGTRGVGKTTIARIFAKALnceTAPtgepcntcEQCRKvtq 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 ----RVLELNASDERGIqvvrEKVKRFAQltVAGTRP-DGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCL 173
Cdd:PRK14959 85 gmhvDVVEIDGASNRGI----DDAKRLKE--AIGYAPmEGR----YKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVL 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 52317098 174 ICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLNSER 250
Cdd:PRK14959 155 ATTEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESR 231
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
38-305 |
3.50e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 70.19 E-value: 3.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTS--TILAAA-------------------REL-YGPD 94
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKNALRFNRAAHaYLFSGIRGTGKTTlaRIFAKAlncqnptedqepcnqcascKEIsSGTS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 95 LyrqRVLELNASDERGIQVVREkvkrfAQLTVAGTRPDGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLI 174
Cdd:PRK06305 90 L---DVLEIDGASHRGIEDIRQ-----INETVLFTPSKSR----YKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 175 CNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnSEREITE 254
Cdd:PRK06305 158 TTEIHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGL-FPKSLDP 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 52317098 255 QTIIEIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQL 305
Cdd:PRK06305 237 DSVAKALGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDL 287
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
27-273 |
3.72e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 70.27 E-value: 3.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 27 EKKQRAVPWVEKYRPKCVDEVAFQEEVVAVLKKS-LEGADLPNLLFYGPPGTGKTST--ILAAARELYGP---------- 93
Cdd:PRK06645 3 NSSNQYIPFARKYRPSNFAELQGQEVLVKVLSYTiLNDRLAGGYLLTGIRGVGKTTSarIIAKAVNCSALitenttiktc 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 94 ----------DLYRQRVLELNASDERGIQVVREKVKRfaqltvAGTRP-DGKtcppFKIIILDEADSMTSAAQAALRRTM 162
Cdd:PRK06645 83 eqctncisfnNHNHPDIIEIDAASKTSVDDIRRIIES------AEYKPlQGK----HKIFIIDEVHMLSKGAFNALLKTL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 163 EKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLA-NDVQQerILE-ICRKENLKYTTEGVDALVRVSEGDLRKAITFL 240
Cdd:PRK06645 153 EEPPPHIIFIFATTEVQKIPATIISRCQRYDLRRLSfEEIFK--LLEyITKQENLKTDIEALRIIAYKSEGSARDAVSIL 230
|
250 260 270
....*....|....*....|....*....|....*
gi 52317098 241 QSGARL--NSEREITEQTIIEIAGVVPPKVIQSLL 273
Cdd:PRK06645 231 DQAASMsaKSDNIISPQVINQMLGLVDSSVIIEFV 265
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
38-241 |
4.63e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 70.22 E-value: 4.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSL-EGADLPNLLFYGPPGTGKTST--ILAAARELYGPDlYRQR--------------- 99
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIaEGRVAHAYLFTGPRGVGKTSTarILAKAVNCTTND-PKGRpcgtcemcraiaegs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 100 ---VLELNASDERGIQVVREKVKRfAQLTVAGTRpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICN 176
Cdd:PRK14950 88 avdVIEMDAASHTSVDDAREIIER-VQFRPALAR--------YKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATT 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 52317098 177 YVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQ 241
Cdd:PRK14950 159 EVHKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQ 223
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
38-305 |
7.31e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 69.51 E-value: 7.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEG-----AdlpnLLFYGPPGTGKTST--ILAAA------------------RE-LY 91
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLKNAIKQgkishA----YLFSGPRGTGKTSAakIFAKAvnclnppdgepcneceicKAiTN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 92 G--PDlyrqrVLELNASDERG---IQVVREKVKrFAqltvagtrP-DGKtcppFKIIILDEADSMTSAAQAALRRTMEKE 165
Cdd:PRK05563 85 GslMD-----VIEIDAASNNGvdeIRDIRDKVK-YA--------PsEAK----YKVYIIDEVHMLSTGAFNALLKTLEEP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 166 SRTTRFCLICNYVSRIiePLT--SRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSG 243
Cdd:PRK05563 147 PAHVIFILATTEPHKI--PATilSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQA 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 52317098 244 ARLNSErEITEQTIIEIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQL 305
Cdd:PRK05563 225 ISFGDG-KVTYEDALEVTGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDL 285
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
38-265 |
1.90e-12 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 68.45 E-value: 1.90e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADL-PNLLFYGPPGTGKTST--ILAaaRELY-----GP--------DLYRQ--- 98
Cdd:PRK14948 9 KYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSarILA--KSLNclnsdKPtpepcgkcELCRAiaa 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 ----RVLELNASDERGIQVVREKVKRfAQLTVAGTRpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLI 174
Cdd:PRK14948 87 gnalDVIEIDAASNTGVDNIRELIER-AQFAPVQAR--------WKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 175 CNYVSRIIEPLTSRCSKFRFK--PLANDVQQerILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnsEREI 252
Cdd:PRK14948 158 TTDPQRVLPTIISRCQRFDFRriPLEAMVQH--LSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQLSLL--PGPI 233
|
250
....*....|...
gi 52317098 253 TEQTIIEIAGVVP 265
Cdd:PRK14948 234 TPEAVWDLLGAVP 246
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
27-253 |
4.91e-12 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 66.90 E-value: 4.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 27 EKKQRAVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-----LLFYGPPGTGKTSTILAAARELyGPDlYRQRV- 100
Cdd:TIGR00602 66 ENLDGNEPWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKEL-GIQ-VQEWSn 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 101 ---LELNASDERGIQVVREKVKRF---------------AQLTVAGTRPDGKTcppfKIIILDEADSMTSAAQAALRRTM 162
Cdd:TIGR00602 144 ptlPDFQKNDHKVTLSLESCFSNFqsqievfsefllratNKLQMLGDDLMTDK----KIILVEDLPNQFYRDTRALHEIL 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 163 E-KESRTTRFCLICnYVSRIIEPLTS--------------------RCSKFRFKPLANDVQQERILEICRKE-------N 214
Cdd:TIGR00602 220 RwKYVSIGRCPLVF-IITESLEGDNNqrrllfpaetimnkeileepRVSNISFNPIAPTIMKKFLNRIVTIEakkngekI 298
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 52317098 215 LKYTTEGVDALVRVSEGDLRKAITFLQ-----SGARLNSEREIT 253
Cdd:TIGR00602 299 KVPKKTSVELLCQGCSGDIRSAINSLQfssskSGSLPIKKRMST 342
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
38-333 |
7.77e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 66.29 E-value: 7.77e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILAAA------------------REL---YGP 93
Cdd:PRK14958 9 KWRPRCFQEVIGQAPVVRALSNALDQQYLHHaYLFTGTRGVGKTtiSRILAKClncekgvsanpcndcencREIdegRFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 94 DLYrqrvlELNASDERGIQVVREKVKRFaqltvagtrPDGKTCPPFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCL 173
Cdd:PRK14958 89 DLF-----EVDAASRTKVEDTRELLDNI---------PYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFIL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 174 ICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFL-QSGARLNSEREI 252
Cdd:PRK14958 155 ATTDHHKLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLdQSIAYGNGKVLI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 253 TE-QTIIEiagVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGY----AATNLLNQLHDVIIEEQLSDKQKSVITEKMA 327
Cdd:PRK14958 235 ADvKTMLG---TIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVdfsnALADLLSLLHQIAIIQTVPEALIENDSEQLR 311
|
....*.
gi 52317098 328 EVDKCL 333
Cdd:PRK14958 312 QLAKLL 317
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
38-315 |
8.21e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 66.27 E-value: 8.21e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILA------------------AARELygpDLY 96
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTTIarILAkslncenaqhgepcgvcqSCTQI---DAG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 97 RQ-RVLELNASDERGIQVVREKVKRFAQLTVAGTrpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLIC 175
Cdd:PRK08691 86 RYvDLLEIDAASNTGIDNIREVLENAQYAPTAGK---------YKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 176 NYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLNSErEITEQ 255
Cdd:PRK08691 157 TDPHKVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSG-KVAEN 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 256 TIIEIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQLhdVIIEEQLS 315
Cdd:PRK08691 236 DVRQMIGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAVGFDNALGEL--AILLQQLA 293
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
45-242 |
2.02e-11 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 64.15 E-value: 2.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 45 DEVAFQEEVVAVLKKSLEGADL-PNLLFYGPPGTGKTSTILAAARELY----GPDLYRQRVLELNASD------------ 107
Cdd:PRK07399 4 ANLIGQPLAIELLTAAIKQNRIaPAYLFAGPEGVGRKLAALCFIEGLLsqgsPSKNIRRRLEEGNHPDllwveptyqhqg 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 108 ---------ERGI------QV----VREkVKRF-AQLTVAGTRpdgktcppfKIIILDEADSMTSAAQAALRRTMEKESR 167
Cdd:PRK07399 84 klitaseaeEAGLkrkappQIrleqIRE-IKRFlSRPPLEAPR---------KVVVIEDAETMNEAAANALLKTLEEPGN 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52317098 168 TTrFCLICNYVSRIIEPLTSRCSKFRFKPLANDvQQERILEIC-RKENLKYTTEGVDALVRVSEGDLRKAITFLQS 242
Cdd:PRK07399 154 GT-LILIAPSPESLLPTIVSRCQIIPFYRLSDE-QLEQVLKRLgDEEILNINFPELLALAQGSPGAAIANIEQLQS 227
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
34-82 |
2.37e-11 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 65.25 E-value: 2.37e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 52317098 34 PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTST 82
Cdd:PRK04132 8 PWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLT 56
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
38-326 |
3.78e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 63.68 E-value: 3.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLE-GADLPNLLFYGPPGTGKTSTILAAAREL-----YGPDLYRQ------------- 98
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSlGRIHHAWLLSGTRGVGKTTIARLLAKSLncqngITSNPCRKciickeiekglcl 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 RVLELNASDERGIQVVREKVKRFAQLTVAGTrpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYV 178
Cdd:PRK14961 89 DLIEIDAASRTKVEEMREILDNIYYSPSKSR---------FKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 179 SRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnSEREITEQTII 258
Cdd:PRK14961 160 EKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINL-GKGNINIKNVT 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 52317098 259 EIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQ----LHDVIIEEQLSDKQKSVITEKM 326
Cdd:PRK14961 239 DMLGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEmlrfLHHISMSQSFPKIWNTIFIKNY 310
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
38-240 |
5.08e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 63.99 E-value: 5.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA------------------RELY---GP 93
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTarILAKAlnceqgltaepcnvcppcVEITegrSV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 94 DlyrqrVLELNASDERGIQVVREkvkrfaqltvagTRPDGKTCPP---FKIIILDEADSMTSAAQAALRRTMEKESRTTR 170
Cdd:PRK14965 89 D-----VFEIDGASNTGVDDIRE------------LRENVKYLPSrsrYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVK 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 52317098 171 FCLICNYVSRIIEPLTSRCSKFRFK--PLANDVQQERilEICRKENLKYTTEGVDALVRVSEGDLRKAITFL 240
Cdd:PRK14965 152 FIFATTEPHKVPITILSRCQRFDFRriPLQKIVDRLR--YIADQEGISISDAALALVARKGDGSMRDSLSTL 221
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
50-198 |
1.13e-10 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 59.53 E-value: 1.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 50 QEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELY----GPDLYR------QRVLELN-------ASDERGI 111
Cdd:pfam13177 2 QPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFceepGDDLPCgqcrscRRIESGNhpdlviiEPEGQSI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 112 QV--VREKVKRFAQLTVAGtrpdgktcpPFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRC 189
Cdd:pfam13177 82 KIdqIRELQKEFSKSPYEG---------KKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRC 152
|
....*....
gi 52317098 190 SKFRFKPLA 198
Cdd:pfam13177 153 QIIRFKPLS 161
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
38-334 |
2.68e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 61.60 E-value: 2.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELYGPDLYRQRVLELNAS-----DERGI 111
Cdd:PRK14960 8 KYRPRNFNELVGQNHVSRALSSALERGRLHHaYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATckavnEGRFI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 112 QVVreKVKRFAQLTVAGTR------PDGKTCPPFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPL 185
Cdd:PRK14960 88 DLI--EIDAASRTKVEDTRelldnvPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 186 TSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITfLQSGARLNSEREITEQTIIEIAGVVP 265
Cdd:PRK14960 166 ISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALS-LTDQAIAYGQGAVHHQDVKEMLGLID 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52317098 266 PKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQ----LHDVIIEEQLSD---KQKSVITEKMAEVDKCLA 334
Cdd:PRK14960 245 RTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQlistLHELALLQYLPElglKYSEEINAKILQLSKLIS 320
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
68-194 |
4.18e-10 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 57.77 E-value: 4.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 68 NLLFYGPPGTGKTSTILAAARELYGPDLyrqRVLELNASDERGIQVVREKVKRFAQLTVAGTRPDG--------KTCPPf 139
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGG---GVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRlrlalalaRKLKP- 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 52317098 140 KIIILDEADSMTSAAQAALRR--------TMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRF 194
Cdd:smart00382 80 DVLILDEITSLLDAEQEALLLlleelrllLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRI 142
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
51-243 |
1.36e-09 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 58.89 E-value: 1.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 51 EEVVAVLKKSLEGADLPN-LLFYGPPGTGKTS-------TILA------AARELYGPD----LYRQ-------RVLELNA 105
Cdd:PRK09112 29 EEAEAFLAQAYREGKLHHaLLFEGPEGIGKATlafhlanHILShpdpaeAPETLADPDpaspVWRQiaqgahpNLLHITR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 106 S-DER------GIQV--VREKVKRFAQltvagTRPDGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICN 176
Cdd:PRK09112 109 PfDEKtgkfktAITVdeIRRVGHFLSQ-----TSGDGN----WRIVIIDPADDMNRNAANAILKTLEEPPARALFILISH 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 52317098 177 YVSRIIEPLTSRCSKFRFKPLANDVQQERILEIcrKENLKYTTEGVDALVRVSEGDLRKAITFLQSG 243
Cdd:PRK09112 180 SSGRLLPTIRSRCQPISLKPLDDDELKKALSHL--GSSQGSDGEITEALLQRSKGSVRKALLLLNYG 244
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
38-259 |
1.39e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 59.40 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA---RELyGPD------------LYRQR 99
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTCarIFAKTincQNL-TADgeacnecescvaFNEQR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 100 ---VLELNASDERGIQVVR---EKVKRFAQLtvagtrpdGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCL 173
Cdd:PRK14971 89 synIHELDAASNNSVDDIRnliEQVRIPPQI--------GK----YKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFIL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 174 ICNYVSRIIEPLTSRCSKFRFkplaNDVQQERILE----ICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLnSE 249
Cdd:PRK14971 157 ATTEKHKILPTILSRCQIFDF----NRIQVADIVNhlqyVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSF-TG 231
|
250
....*....|
gi 52317098 250 REITEQTIIE 259
Cdd:PRK14971 232 GNITYKSVIE 241
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
38-312 |
4.89e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 57.96 E-value: 4.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILAAARELYGPDL------------------- 95
Cdd:PRK12323 9 KWRPRDFTTLVGQEHVVRALTHALEQQRLHHaYLFTGTRGVGKTtlSRILAKSLNCTGADGeggitaqpcgqcracteid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 96 ------YrqrvLELNASDERGIQVVREKVKRFAQLTVAGTrpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTT 169
Cdd:PRK12323 89 agrfvdY----IEMDAASNRGVDEMAQLLDKAVYAPTAGR---------FKVYMIDEVHMLTNHAFNAMLKTLEEPPEHV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 170 RFCLICNYVSRIiePLT--SRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITflqsgarln 247
Cdd:PRK12323 156 KFILATTDPQKI--PVTvlSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALS--------- 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 52317098 248 sereITEQTIIEIAGVVPpkviqsllhicykgtfeklEVAVKDM---IDQGYaatnlLNQLHDVIIEE 312
Cdd:PRK12323 225 ----LTDQAIAYSAGNVS-------------------EEAVRGMlgaIDQSY-----LVRLLDALAAE 264
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
38-260 |
5.43e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 57.65 E-value: 5.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA----RELYGPDlYRQRVLE-------- 102
Cdd:PRK14954 9 KYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAarVFAKAvncqRMIDDPV-YLQEVTEpcgecesc 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 103 --------LNASDERG--------IQVVREKVKRFAQltvagtrpDGKtcppFKIIILDEADSMTSAAQAALRRTMEKES 166
Cdd:PRK14954 88 rdfdagtsLNISEFDAasnnsvddIRQLRENVRYGPQ--------KGR----YRVYIIDEVHMLSTAAFNAFLKTLEEPP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 167 RTTRFCLICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQS---- 242
Cdd:PRK14954 156 PHAIFIFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQviaf 235
|
250
....*....|....*...
gi 52317098 243 GARLNSEREITEQTIIEI 260
Cdd:PRK14954 236 SVGSEAEKVIAYQGVAEL 253
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
38-308 |
7.28e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 57.01 E-value: 7.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELYGPDLYRQR----------------- 99
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSLVHALETQKVHHaYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEpcnkcencvainnnsfi 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 100 -VLELNASDERGIQVVREKVKRFAQLTVAGTrpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYV 178
Cdd:PRK14957 89 dLIEIDAASRTGVEETKEILDNIQYMPSQGR---------YKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 179 SRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLNSErEITEQTII 258
Cdd:PRK14957 160 HKIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGG-ELKQAQIK 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 52317098 259 EIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQLHDV 308
Cdd:PRK14957 239 QMLGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEI 288
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
38-238 |
1.01e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 56.65 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILAAARELYGPD-------------------- 94
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTNALTQQRLHHaYLFTGTRGVGKTtvSRILAKSLNCQGPDgqggitatpcgvcqacrdid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 95 -----LYrqrvLELNASDERGIQVVREKVKRFAQLTVAGTrpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTT 169
Cdd:PRK14951 89 sgrfvDY----TELDAASNRGVDEVQQLLEQAVYKPVQGR---------FKVFMIDEVHMLTNTAFNAMLKTLEEPPEYL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 52317098 170 RFCLICNYVSRIiePLT--SRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAIT 238
Cdd:PRK14951 156 KFVLATTDPQKV--PVTvlSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALS 224
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
38-240 |
1.07e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 56.68 E-value: 1.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILA------------------AARELYGP--- 93
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRALTNALEQQRLHHaYLFTGTRGVGKTtlARILAkslncetgvtatpcgvcsACLEIDSGrfv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 94 DLyrqrvLELNASDERGIQVVREKVKRfAQLTVAGTRpdgktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCL 173
Cdd:PRK14969 89 DL-----IEVDAASNTQVDAMRELLDN-AQYAPTRGR--------FKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFIL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 52317098 174 ICNYVSRIiePLT--SRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFL 240
Cdd:PRK14969 155 ATTDPQKI--PVTvlSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLL 221
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
205-260 |
2.02e-08 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 50.55 E-value: 2.02e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 52317098 205 RILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLNSEREITEQTIIEI 260
Cdd:cd18133 9 RLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDDGKISLDRVYQA 64
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
38-257 |
2.91e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 55.63 E-value: 2.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILA------------------AARELygpDLY 96
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTtlSRIFAkalncetgvtsqpcgvcrACREI---DEG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 97 R-QRVLELNASDERGIQVVREKVKRFAQLTVagtrpDGKtcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLIC 175
Cdd:PRK07003 86 RfVDYVEMDAASNRGVDEMAALLERAVYAPV-----DAR----FKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 176 NYVSRIiePLT--SRCSKFRFK--PLANDVQQ-ERILEicrKENLKYTTEGVDALVRVSEGDLRKAITfLQSGARLNSER 250
Cdd:PRK07003 157 TDPQKI--PVTvlSRCLQFNLKqmPAGHIVSHlERILG---EERIAFEPQALRLLARAAQGSMRDALS-LTDQAIAYSAN 230
|
....*..
gi 52317098 251 EITEQTI 257
Cdd:PRK07003 231 EVTETAV 237
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
38-260 |
3.32e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 54.90 E-value: 3.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 38 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA----RELYGPDLYRQ------------ 98
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAarVFAKAvncqRMIDDADYLQEvtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 99 --------RVLELNASDERG---IQVVREKVKRFAQltvagtrpDGKtcppFKIIILDEADSMTSAAQAALRRTMEKESR 167
Cdd:PRK14955 89 dfdagtslNISEFDAASNNSvddIRLLRENVRYGPQ--------KGR----YRVYIIDEVHMLSIAAFNAFLKTLEEPPP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 168 TTRFCLICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQS----G 243
Cdd:PRK14955 157 HAIFIFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQviafS 236
|
250
....*....|....*..
gi 52317098 244 ARLNSEREITEQTIIEI 260
Cdd:PRK14955 237 VESEGEGSIRYDKVAEL 253
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
45-261 |
1.06e-07 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 52.19 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 45 DEVAFQEEVVAVLK---KSLEGADLP---------NLLFYGPPGTGKTSTILAAARELygpdlyRQRVLELNASDERGiQ 112
Cdd:COG1223 2 DDVVGQEEAKKKLKliiKELRRRENLrkfglwpprKILFYGPPGTGKTMLAEALAGEL------KLPLLTVRLDSLIG-S 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 113 VVREKVKRFAQL-TVAGTRPdgktCppfkIIILDEADSMtsaaqaALRRTMEK----------------ESRTTRFCLIC 175
Cdd:COG1223 75 YLGETARNLRKLfDFARRAP----C----VIFFDEFDAI------AKDRGDQNdvgevkrvvnallqelDGLPSGSVVIA 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 176 --NYVSRIIEPLTSRCS-KFRFkPLANDVQQERILEICRKENLKYTTEGVDALVRVSEG----DLRKAITFLQSGARLNS 248
Cdd:COG1223 141 atNHPELLDSALWRRFDeVIEF-PLPDKEERKEILELNLKKFPLPFELDLKKLAKKLEGlsgaDIEKVLKTALKKAILED 219
|
250
....*....|...
gi 52317098 249 EREITEQtIIEIA 261
Cdd:COG1223 220 REKVTKE-DLEEA 231
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
27-90 |
1.62e-07 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 50.73 E-value: 1.62e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 52317098 27 EKKQRAVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-----LLFYGPPGTGKTSTILAAAREL 90
Cdd:pfam03215 1 INDDGGEQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL 69
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
67-188 |
5.22e-07 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 48.82 E-value: 5.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 67 PNLLFYGPPGTGKTSTILAAARELyGPDLYRQRVLELNasdERGIQVVREKVKR-FAQLtvagtrpdgKTCPPfKIIILD 145
Cdd:cd19481 27 KGILLYGPPGTGKTLLAKALAGEL-GLPLIVVKLSSLL---SKYVGESEKNLRKiFERA---------RRLAP-CILFID 92
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 52317098 146 EADSM-----TSAAQAALRRT-------MEKESRTTRFCLIC--NYVSRIIEPLTSR 188
Cdd:cd19481 93 EIDAIgrkrdSSGESGELRRVlnqllteLDGVNSRSKVLVIAatNRPDLLDPALLRP 149
|
|
| PRK07471 |
PRK07471 |
DNA polymerase III subunit delta'; Validated |
70-244 |
6.16e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236022 [Multi-domain] Cd Length: 365 Bit Score: 50.80 E-value: 6.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 70 LFYGPPGTGKTSTILAAARELY-----GPDLYRQRV--LELNASD----------ERGIQVVR----EKVKRF-AQLTVA 127
Cdd:PRK07471 45 LIGGPQGIGKATLAYRMARFLLatpppGGDGAVPPPtsLAIDPDHpvarriaagaHGGLLTLErswnEKGKRLrTVITVD 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 128 GTRpdgKTCPPF---------KIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLA 198
Cdd:PRK07471 125 EVR---ELISFFgltaaeggwRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRPLA 201
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 52317098 199 NDVQQeRILEICRKENLkytTEGVDALVRVSEGDLRKAITFLQSGA 244
Cdd:PRK07471 202 PEDVI-DALAAAGPDLP---DDPRAALAALAEGSVGRALRLAGGDG 243
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
40-90 |
1.13e-06 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 47.88 E-value: 1.13e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 52317098 40 RPKCVDEVAFQEEVVAVLKKSLEGAD-----LPNLLFYGPPGTGKTSTILAAAREL 90
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFIEAAKqrgeaLDHVLLYGPPGLGKTTLANIIANEM 57
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
69-259 |
2.91e-06 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 48.75 E-value: 2.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 69 LLFYGPPGTGKTSTILAAARELYGPdlyrqrVLELNASD---------ERGIqvvREKVKRFAQLTVAgtrpdgktcppf 139
Cdd:COG0464 194 LLLYGPPGTGKTLLARALAGELGLP------LIEVDLSDlvskyvgetEKNL---REVFDKARGLAPC------------ 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 140 kIIILDEADSMTSAAQAALRRTMEK---------ESRTTRFCLIC--NYVSRIIEPLTSRC-SKFRFkPLANDVQQERIL 207
Cdd:COG0464 253 -VLFIDEADALAGKRGEVGDGVGRRvvntlltemEELRSDVVVIAatNRPDLLDPALLRRFdEIIFF-PLPDAEERLEIF 330
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 52317098 208 EI-CRKENLkytTEGVD--ALVRVSEG----DLRKAITFLQSGARLNSEREITEQTIIE 259
Cdd:COG0464 331 RIhLRKRPL---DEDVDleELAEATEGlsgaDIRNVVRRAALQALRLGREPVTTEDLLE 386
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
70-257 |
8.42e-06 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 46.48 E-value: 8.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 70 LFYGPPGTGKTSTILAAARELYG------PDLYRQRVL------ELNASDERG-IQVVREKVKRFAQLTVagtRPdgktc 136
Cdd:COG2842 54 VVYGESGVGKTTAAREYANRNPNviyvtaSPSWTSKELleelaeELGIPAPPGtIADLRDRILERLAGTG---RL----- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 137 ppfkiIILDEADSMTSAAQAALRR------------TMEK-ESRTTRFCLIcnyVSRIIEpltsrcsKFRFKPL-ANDVQ 202
Cdd:COG2842 126 -----LIIDEADHLKPKALEELRDihdetgvgvvliGMERlPAKLKRYEQL---YSRIGF-------WVEFKPLsLEDVR 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 52317098 203 QerILEICrkENLKyTTEGVDALVRVSEGDLR---KAITFLQSGARLNSEREITEQTI 257
Cdd:COG2842 191 A--LAEAW--GELT-DPDLLELLHRITRGNLRrldRTLRLAARAAKRNGLTKITLDHV 243
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
140-318 |
9.09e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 46.95 E-value: 9.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 140 KIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLAndvqQERILEICRKENLKYTT 219
Cdd:PRK05564 95 KVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLS----KEEIEKFISYKYNDIKE 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 220 EGVDALVRVSEGDLRKAITFLQSgarlNSEREItEQTIIEIagvvppkvIQSLLHICYKGTFEKLEVAVKDMIDQGYAAT 299
Cdd:PRK05564 171 EEKKSAIAFSDGIPGKVEKFIED----DSLKNI-RNMSLEI--------LKDIKKSNINILLKYENFLIKYKENWEEILT 237
|
170
....*....|....*....
gi 52317098 300 NLLNQLHDVIIEEQLSDKQ 318
Cdd:PRK05564 238 CILSYIRDSLLYKETGNEE 256
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
40-90 |
9.99e-06 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 46.66 E-value: 9.99e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 52317098 40 RPKCVDEVAFQEEVVAVLKKSLEGAD-----LPNLLFYGPPGTGKTStiLAA--AREL 90
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFIEAAKkrgeaLDHVLLYGPPGLGKTT--LANiiANEM 75
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
51-254 |
1.93e-05 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 45.99 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 51 EEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL------YGPDLY-----------RQRVL-----ELNASDE 108
Cdd:COG1474 36 EELASALRPALRGERPSNVLIYGPTGTGKTAVAKYVLEELeeeaeeRGVDVRvvyvncrqastRYRVLsrileELGSGED 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 109 ---RGIQvVREKVKRFAQLTVAGTRPdgktcppfKIIILDEADSMTSAAQ----AALRRTMEkESRTTRFCLICnyVSR- 180
Cdd:COG1474 116 ipsTGLS-TDELFDRLYEALDERDGV--------LVVVLDEIDYLVDDEGddllYQLLRANE-ELEGARVGVIG--ISNd 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 181 --IIEPLTSR------CSKFRFKPLanDVQQER-ILEICRKENLKyttEGV---DALVRVSE------GDLRKAITFLQS 242
Cdd:COG1474 184 leFLENLDPRvksslgEEEIVFPPY--DADELRdILEDRAELAFY---DGVlsdEVIPLIAAlaaqehGDARKAIDLLRV 258
|
250
....*....|....*
gi 52317098 243 GARL---NSEREITE 254
Cdd:COG1474 259 AGEIaerEGSDRVTE 273
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
51-94 |
4.29e-05 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 45.15 E-value: 4.29e-05
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 52317098 51 EEVVAVLKKSlegadlPNLLFYGPPGTGKTSTILAAARELYGPD 94
Cdd:COG1401 212 EAFLAALKTK------KNVILAGPPGTGKTYLARRLAEALGGED 249
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
40-90 |
7.05e-05 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 44.30 E-value: 7.05e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 52317098 40 RPKCVDEVAFQEEVVAVLKKSLEGAD-----LPNLLFYGPPGTGKT--STILaaAREL 90
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIEAAKkrgeaLDHVLLYGPPGLGKTtlAHII--ANEM 78
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
69-174 |
1.14e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 41.56 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 69 LLFYGPPGTGKTSTILAAARELygpDLYRQRVLELNASDERGIQVVREKVKRFAQLTVAGTRP----------DGKTCPP 138
Cdd:pfam13401 8 LVLTGESGTGKTTLLRRLLEQL---PEVRDSVVFVDLPSGTSPKDLLRALLRALGLPLSGRLSkeellaalqqLLLALAV 84
|
90 100 110
....*....|....*....|....*....|....*.
gi 52317098 139 FKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLI 174
Cdd:pfam13401 85 AVVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
45-90 |
1.19e-04 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 43.46 E-value: 1.19e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 52317098 45 DEVAFQEEVVAVLKKSLE------------GADLPN-LLFYGPPGTGKTSTILAAAREL 90
Cdd:COG1222 78 DDIGGLDEQIEEIREAVElplknpelfrkyGIEPPKgVLLYGPPGTGKTLLAKAVAGEL 136
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
73-157 |
1.39e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 42.17 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 73 GPPGTGKTsTILAAARELYGPDLYRQRVLelnASDERGIQVVREKVKrFAQLTVA---GTRPDGKTCPPFKIIILDEAdS 149
Cdd:pfam13604 25 GPAGTGKT-TALKALREAWEAAGYRVIGL---APTGRAAKVLGEELG-IPADTIAkllHRLGGRAGLDPGTLLIVDEA-G 98
|
....*...
gi 52317098 150 MTSAAQAA 157
Cdd:pfam13604 99 MVGTRQMA 106
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
69-167 |
1.49e-04 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 41.89 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 69 LLFYGPPGTGKTSTILAAARE-------LYGPDLYRQRVLElnasDERGIQVVREKVKRFAQltvagtrpdgktcppfKI 141
Cdd:cd19503 37 VLLHGPPGTGKTLLARAVANEaganflsISGPSIVSKYLGE----SEKNLREIFEEARSHAP----------------SI 96
|
90 100
....*....|....*....|....*.
gi 52317098 142 IILDEADSMTSAAQAALRrtmEKESR 167
Cdd:cd19503 97 IFIDEIDALAPKREEDQR---EVERR 119
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
207-262 |
1.86e-04 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 39.54 E-value: 1.86e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 52317098 207 LEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARL---NSEREITEQTIIEIAG 262
Cdd:cd18139 17 KERGGDRKVTIDDEALELLAEAADGDARSALNLLELAVLSaeeDGGIVITLEDLEEVLQ 75
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
50-91 |
2.15e-04 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 42.22 E-value: 2.15e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 52317098 50 QEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELY 91
Cdd:cd18038 4 DEQKLAVRNIVTGTSRPPPYIIFGPPGTGKTVTLVEAILQVL 45
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
73-174 |
3.68e-04 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 39.91 E-value: 3.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 73 GPPGTGKTSTILAAARELygpdlyrqrvleLNASDERGIQVVrekvkrfAQLTVAGTRPDgktcppfkIIILDEAdSMTS 152
Cdd:cd17934 6 GPPGTGKTTTIAAIVLQL------------LKGLRGKRVLVT-------AQSNVAVDNVD--------VVIIDEA-SQIT 57
|
90 100
....*....|....*....|..
gi 52317098 153 AAQAALRRtmekeSRTTRFCLI 174
Cdd:cd17934 58 EPELLIAL-----IRAKKVVLV 74
|
|
| PRK08058 |
PRK08058 |
DNA polymerase III subunit delta'; Validated |
50-208 |
4.04e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181214 [Multi-domain] Cd Length: 329 Bit Score: 41.83 E-value: 4.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 50 QEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELYGPDLYR----------QRVLELN-------ASDERGI 111
Cdd:PRK08058 11 QPVVVKMLQNSIAKNRLSHaYLFEGAKGTGKKATALWLAKSLFCLERNGvepcgtctncKRIDSGNhpdvhlvAPDGQSI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 112 QV--VREKVKRFAQLTVAGTRpdgktcppfKIIILDEADSMT-SAAQAALRRTMEKESRTTRFCLICNYvSRIIEPLTSR 188
Cdd:PRK08058 91 KKdqIRYLKEEFSKSGVESNK---------KVYIIEHADKMTaSAANSLLKFLEEPSGGTTAILLTENK-HQILPTILSR 160
|
170 180
....*....|....*....|
gi 52317098 189 CSKFRFKPLANDVQQERILE 208
Cdd:PRK08058 161 CQVVEFRPLPPESLIQRLQE 180
|
|
| DUF2075 |
pfam09848 |
Schlafen group 3, DNA/RNA helicase domain; This domain is found in at the C terminus of group ... |
69-161 |
4.64e-04 |
|
Schlafen group 3, DNA/RNA helicase domain; This domain is found in at the C terminus of group 3 Schlafen proteins from mammals, and represents the DNA/RNA helicase domain. Schlafen proteins are involved in the control of cell proliferation, induction of immune responses, and in the regulation of viral replication. These proteins inhibit DNA replication and promote cell death in response to DNA damage. They play a role in genome surveillance to kill cells with defective replication. This domain is also found in various uncharacterized prokaryotic proteins fused to a DNA helicase, GIY-YIG or PD-(D/E)XK catalytic domain or HsdR-N(terminal) domain, which are similar to AAA DNA helicase, Type III restriction enzyme ATPase, RecD and RuvB helicase.
Pssm-ID: 430875 [Multi-domain] Cd Length: 355 Bit Score: 41.88 E-value: 4.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 69 LLFYGPPGTGKTSTILAAARELYGPDLYRQRVLELNASDERgiQVVREKVKR----------FAQLTVAGTRPDgKTCPP 138
Cdd:pfam09848 4 FLVTGGPGTGKTVIGLNLFAELEDSDLGRTAVYLSGNHPLV--LVLYEALAGdlrkkrkksaFQRPTSFINNLH-KTHPH 80
|
90 100
....*....|....*....|...
gi 52317098 139 FKIIILDEADSMTSAAQAALRRT 161
Cdd:pfam09848 81 EDVVIFDEAHRLWDKSDPYNNFS 103
|
|
| RecA-like_BCS1 |
cd19510 |
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ... |
70-109 |
4.75e-04 |
|
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410918 [Multi-domain] Cd Length: 153 Bit Score: 40.03 E-value: 4.75e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 52317098 70 LFYGPPGTGKTSTILAAARELyGPDLYRQRVLELNASDER 109
Cdd:cd19510 27 LLYGPPGTGKSSFIAALAGEL-DYDICDLNLSEVVLTDDR 65
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
48-153 |
4.86e-04 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 40.34 E-value: 4.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 48 AFQEEVVAVLKKSLE----GADLPN-LLFYGPPGTGKTSTILAAARE-------LYGPDLYRQRVLElnasDERGiqvVR 115
Cdd:cd19511 4 ELKEAVEWPLKHPDAfkrlGIRPPKgVLLYGPPGCGKTLLAKALASEaglnfisVKGPELFSKYVGE----SERA---VR 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 52317098 116 EKVKRFAQLTVAgtrpdgktcppfkIIILDEADSMTSA 153
Cdd:cd19511 77 EIFQKARQAAPC-------------IIFFDEIDSLAPR 101
|
|
| TIGR02928 |
TIGR02928 |
orc1/cdc6 family replication initiation protein; Members of this protein family are found ... |
51-90 |
6.82e-04 |
|
orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274354 [Multi-domain] Cd Length: 365 Bit Score: 41.08 E-value: 6.82e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 52317098 51 EEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL 90
Cdd:TIGR02928 25 EELAKALRPILRGSRPSNVFIYGKTGTGKTAVTKYVMKEL 64
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
51-160 |
7.67e-04 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 39.79 E-value: 7.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 51 EEVVAVLKKSLEGaDLPNLLFYGPPGTGKTSTILAAARELYGPDLYrqrVLELNASDERGIQVVREKVKRFAQLTVAGTR 130
Cdd:pfam13191 10 EQLLDALDRVRSG-RPPSVLLTGEAGTGKTTLLRELLRALERDGGY---FLRGKCDENLPYSPLLEALTREGLLRQLLDE 85
|
90 100 110
....*....|....*....|....*....|
gi 52317098 131 PDGKTCPPFKIIILDEADSMTSAAQAALRR 160
Cdd:pfam13191 86 LESSLLEAWRAALLEALAPVPELPGDLAER 115
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
139-201 |
8.44e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 40.94 E-value: 8.44e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 52317098 139 FKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLANDV 201
Cdd:PRK06090 109 YRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQ 171
|
|
| DEXXQc_HELZ2-N |
cd18076 |
N-terminal DEXXQ-box helicase domain of HELZ2; Helicase with zinc finger 2 (HELZ2, also known ... |
50-90 |
1.19e-03 |
|
N-terminal DEXXQ-box helicase domain of HELZ2; Helicase with zinc finger 2 (HELZ2, also known as PPAR-alpha-interacting complex protein 285 or PRIC285 and PPAR-gamma DBD-interacting protein 1 or PDIP1) acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB, and RXRA. It belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350834 [Multi-domain] Cd Length: 230 Bit Score: 39.87 E-value: 1.19e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 52317098 50 QEEVVA-VLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL 90
Cdd:cd18076 6 QQLAFNfIAGKPSEARFVPPLLIYGPFGTGKTFTLAMAALEV 47
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
69-204 |
1.59e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 40.07 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 69 LLFYGPPGTGKTSTI--LAAA------RELYG---------------PDLYrqrVLELNASDeRGIQV--VREKVKrFAQ 123
Cdd:PRK05707 25 YLLHGPAGIGKRALAerLAAAllceapQGGGAcgsckgcqllragshPDNF---VLEPEEAD-KTIKVdqVRELVS-FVV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 124 LTvagTRPDGktcppFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLANDVQQ 203
Cdd:PRK05707 100 QT---AQLGG-----RKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESL 171
|
.
gi 52317098 204 E 204
Cdd:PRK05707 172 Q 172
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
68-205 |
1.72e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 38.04 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 68 NLLFYGPPGTGKTSTILAAARELYG-PDLYRQRVLELNASDERGIQVVREKVKRFAQ--LTVAGTRPDgktcppfkIIIL 144
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNrPVFYVQLTRDTTEEDLFGRRNIDPGGASWVDgpLVRAAREGE--------IAVL 72
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 52317098 145 DEADSMTSAAQAALRRTMEkesrtTRFCLICNYVSRIIEPLTSrcskFRFKPLANDVQQER 205
Cdd:pfam07728 73 DEINRANPDVLNSLLSLLD-----ERRLLLPDGGELVKAAPDG----FRLIATMNPLDRGL 124
|
|
| cdc6 |
PRK00411 |
ORC1-type DNA replication protein; |
51-90 |
2.83e-03 |
|
ORC1-type DNA replication protein;
Pssm-ID: 234751 [Multi-domain] Cd Length: 394 Bit Score: 39.45 E-value: 2.83e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 52317098 51 EEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL 90
Cdd:PRK00411 40 EELAFALRPALRGSRPLNVLIYGPPGTGKTTTVKKVFEEL 79
|
|
| RecA-like_Lon |
cd19500 |
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ... |
52-90 |
3.54e-03 |
|
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410908 [Multi-domain] Cd Length: 182 Bit Score: 37.92 E-value: 3.54e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 52317098 52 EVVAV--LKKSLEGadlPNLLFYGPPGTGKTSTILAAAREL 90
Cdd:cd19500 24 EYLAVrkLKGSMKG---PILCLVGPPGVGKTSLGKSIARAL 61
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
48-147 |
4.03e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 39.24 E-value: 4.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 48 AFQEEVVAVLKKSLEGADlPNLLFYGPPGTGKTSTILAAARELYGPdlyrQRVL------ELN--ASDE-----RGIQVV 114
Cdd:COG1061 83 PYQQEALEALLAALERGG-GRGLVVAPTGTGKTVLALALAAELLRG----KRVLvlvprrELLeqWAEElrrflGDPLAG 157
|
90 100 110
....*....|....*....|....*....|....*....
gi 52317098 115 REKVKRFAQLTVA-----GTRPDGKTCPP-FKIIILDEA 147
Cdd:COG1061 158 GGKKDSDAPITVAtyqslARRAHLDELGDrFGLVIIDEA 196
|
|
| ftsH |
CHL00176 |
cell division protein; Validated |
51-87 |
4.33e-03 |
|
cell division protein; Validated
Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 38.88 E-value: 4.33e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 52317098 51 EEVVAVLKKS----LEGADLPN-LLFYGPPGTGKtsTILAAA 87
Cdd:CHL00176 196 EEVVSFLKKPerftAVGAKIPKgVLLVGPPGTGK--TLLAKA 235
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
70-187 |
5.17e-03 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 38.34 E-value: 5.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 70 LFYGPPGTGKTSTIL------AAARELYGPDLYRQRVLELNASDERGiqvvrEKVKRFAQLTVAGTRPDGKTCPPFKIII 143
Cdd:COG3598 17 LLAGPPGTGKSFLALqlaaavAAGGPWLGRRVPPGKVLYLAAEDDRG-----ELRRRLKALGADLGLPFADLDGRLRLLS 91
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 52317098 144 LDEADSMTSAAQAalrrtMEKESRTTRFCLIcnyvsrIIEPLTS 187
Cdd:COG3598 92 LAGDLDDTDDLEA-----LERAIEEEGPDLV------VIDPLAR 124
|
|
| Lon |
COG0466 |
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, ... |
55-81 |
5.29e-03 |
|
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440234 [Multi-domain] Cd Length: 785 Bit Score: 38.84 E-value: 5.29e-03
10 20
....*....|....*....|....*....
gi 52317098 55 AV--LKKSLEGadlPNLLFYGPPGTGKTS 81
Cdd:COG0466 342 AVrkLKKKLKG---PILCLVGPPGVGKTS 367
|
|
| DEXXQc_SF1 |
cd18043 |
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are ... |
51-160 |
8.03e-03 |
|
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are nucleic acid motor proteins that couple ATP hydrolysis to translocation along with the concomitant unwinding of DNA or RNA. This is central to many aspects of cellular DNA and RNA metabolism and accordingly, they are implicated in a wide range of nucleic acid processing events including DNA replication, recombination, and repair as well as many aspects of RNA metabolism. Superfamily 1 helicases are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350801 [Multi-domain] Cd Length: 127 Bit Score: 36.02 E-value: 8.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52317098 51 EEVVAVLKKSLEGadlPNLLFYGPPGTGKTSTILAAARELygpdLYR-QRVLeLNASDERGIQVVREKVKRFAQLTVAGT 129
Cdd:cd18043 2 SSQEAAIISARNG---KNVVIQGPPGTGKSQTIANIIANA----LARgKRVL-FVSEKKAALDVVRFPCWIMSPLSVSQY 73
|
90 100 110
....*....|....*....|....*....|..
gi 52317098 130 RPDGKtcPPFKIIILDEADSM-TSAAQAALRR 160
Cdd:cd18043 74 LPLNR--NLFDLVIFDEASQIpIEEALPALFR 103
|
|
| |
