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Conserved domains on  [gi|446282268|ref|WP_000360123|]
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MULTISPECIES: GABA permease [Bacillus]

Protein Classification

amino acid permease( domain architecture ID 11438095)

amino acid permease facilitates the transport of amino acids; similar to Mycobacterium tuberculosis L-asparagine permease

Gene Ontology:  GO:0055085|GO:0006865|GO:0016020|GO:0015171
PubMed:  10931886|24038584|25043943
TCDB:  2.A.3.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
2-448 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


:

Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 574.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   2 DKNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAI 81
Cdd:COG1113   10 EEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFSDYAREYL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  82 GPWAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLF 161
Cdd:COG1113   90 GPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIKVVAIVAF 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 162 LCLGLAVIL-GF-VPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWR 239
Cdd:COG1113  170 IVVGLLLIFfGFgLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKAINSVIWR 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 240 ILVFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAF 319
Cdd:COG1113  250 ILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAERGDAPKFF 329

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 320 LKLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKMWFFP 399
Cdd:COG1113  330 GKLSKRGVPVRAILLSAVVLLIGVVLNYLLPEKAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGAAALKFKMPGFP 409

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
gi 446282268 400 YVTYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKN 448
Cdd:COG1113  410 YTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRRA 458
 
Name Accession Description Interval E-value
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
2-448 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 574.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   2 DKNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAI 81
Cdd:COG1113   10 EEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFSDYAREYL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  82 GPWAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLF 161
Cdd:COG1113   90 GPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIKVVAIVAF 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 162 LCLGLAVIL-GF-VPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWR 239
Cdd:COG1113  170 IVVGLLLIFfGFgLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKAINSVIWR 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 240 ILVFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAF 319
Cdd:COG1113  250 ILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAERGDAPKFF 329

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 320 LKLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKMWFFP 399
Cdd:COG1113  330 GKLSKRGVPVRAILLSAVVLLIGVVLNYLLPEKAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGAAALKFKMPGFP 409

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
gi 446282268 400 YVTYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKN 448
Cdd:COG1113  410 YTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRRA 458
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
 5-447 0e+00

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 530.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268    5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPW 84
Cdd:TIGR01773  10 LPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAIGRW 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   85 AGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCL 164
Cdd:TIGR01773  90 AGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAFIIL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  165 GLAVILGFVPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFF 244
Cdd:TIGR01773 170 GAVAIFGFAPGSEVSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWRIIVFY 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  245 IGSIAVVVTLLPWNSANILKS-PFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLN 323
Cdd:TIGR01773 250 LGSIFIVVALLPWNSPNLLEVgSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPRVFMKLN 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  324 SSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMgRVEQQNLKVKMWFFPYVTY 403
Cdd:TIGR01773 330 KKGVPVQAVLASTFFSFLTVVVNYFAPDKVFLFLVNSSGAIALLVYLVIAVSQLRMRKKL-KANGEAIKIRMWLYPWLTW 408

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 446282268  404 VTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNK 447
Cdd:TIGR01773 409 LVIIFICGILVSMLFIPSMRDEVLLTGLLTIIVLCSYLVFARRK 452
PRK10197 PRK10197
GABA permease;
16-447 3.08e-117

GABA permease;


Pssm-ID: 182297  Cd Length: 446  Bit Score: 350.85  E-value: 3.08e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  16 MISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPWAGYTIGWLYWF 95
Cdd:PRK10197   1 MLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  96 FWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCLGLAVILGFVPG 175
Cdd:PRK10197  81 FWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLGAVAISGFYPY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 176 TEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFFIGSIAVVVTLL 255
Cdd:PRK10197 161 AEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALI 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 256 PWNSANILK-SPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLNSSGVPVRAVLF 334
Cdd:PRK10197 241 PWNMPGLKAvGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPYVAVLL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 335 GTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMgRVEQQNLKVKMWFFPYVTYVTIAAIIAVLI 414
Cdd:PRK10197 321 STGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKIL-RAEGSEIRLRMWLYPWLTWLVIGFITFVLV 399

                        410       420       430
                 ....*....|....*....|....*....|...
gi 446282268 415 AMLAIESLRSQALLTMLVTVLIIISYFIFNRNK 447
Cdd:PRK10197 400 VMLFRPAQQLEVISTGLLAIGIICTVPIMARWK 432
AA_permease pfam00324
Amino acid permease;
13-447 5.74e-96

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 296.92  E-value: 5.74e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   13 HITMISIGGVIGAGLFVGSGAVVHSAGPGS-IVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPWAGYTIGW 91
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGaLLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   92 LYWFFWVIVIAIEATAGAGIIQYW--IPEIPLW-LLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCLGLAV 168
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWelVPDIPYLwVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  169 ILGFVPGTEAPGTS--NLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFFIG 246
Cdd:pfam00324 161 LSGGNPNDGAIFRYlgDNGGKNNFPPGFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  247 SIAVVVTLLPWNSANILK------SPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFL 320
Cdd:pfam00324 241 SLLAIGLLVPWNDPGLLNdsasaaSPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  321 KLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMG--RVEQQNLKVKMWFF 398
Cdd:pfam00324 321 KVDKRGVPLRAILVSMVISLLALLLASLNPAIVFNFLLAISGLSGLIVWGLISLSHLRFRKAFKyqGRSIDELPFKAPLG 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446282268  399 PYVTYVTIAAIIAVLIAMLAIESLRS-------------QALLTMLVTVLIIISYFIFNRNK 447
Cdd:pfam00324 401 PLGVILGLAAIIIILIIQFLYAFLPVpggpknwgagsfaAAYLIVLLFLIILIGVKLHVKNW 462
 
Name Accession Description Interval E-value
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
2-448 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 574.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   2 DKNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAI 81
Cdd:COG1113   10 EEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFSDYAREYL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  82 GPWAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLF 161
Cdd:COG1113   90 GPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIKVVAIVAF 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 162 LCLGLAVIL-GF-VPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWR 239
Cdd:COG1113  170 IVVGLLLIFfGFgLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKAINSVIWR 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 240 ILVFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAF 319
Cdd:COG1113  250 ILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAERGDAPKFF 329

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 320 LKLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKMWFFP 399
Cdd:COG1113  330 GKLSKRGVPVRAILLSAVVLLIGVVLNYLLPEKAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGAAALKFKMPGFP 409

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
gi 446282268 400 YVTYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKN 448
Cdd:COG1113  410 YTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRRA 458
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
 5-447 0e+00

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 530.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268    5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPW 84
Cdd:TIGR01773  10 LPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAIGRW 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   85 AGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCL 164
Cdd:TIGR01773  90 AGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAFIIL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  165 GLAVILGFVPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFF 244
Cdd:TIGR01773 170 GAVAIFGFAPGSEVSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWRIIVFY 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  245 IGSIAVVVTLLPWNSANILKS-PFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLN 323
Cdd:TIGR01773 250 LGSIFIVVALLPWNSPNLLEVgSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPRVFMKLN 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  324 SSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMgRVEQQNLKVKMWFFPYVTY 403
Cdd:TIGR01773 330 KKGVPVQAVLASTFFSFLTVVVNYFAPDKVFLFLVNSSGAIALLVYLVIAVSQLRMRKKL-KANGEAIKIRMWLYPWLTW 408

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 446282268  404 VTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNK 447
Cdd:TIGR01773 409 LVIIFICGILVSMLFIPSMRDEVLLTGLLTIIVLCSYLVFARRK 452
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
2-460 3.27e-161

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 463.87  E-value: 3.27e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   2 DKNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGP-GSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREA 80
Cdd:COG0833    7 QNKLKRGLKSRHLSMIALGGVIGTGLFLASGYTISQAGPgGALLAYLLGGLMVYFLMTSLGELAVAMPVSGSFQTYATRF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  81 IGPWAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVL 160
Cdd:COG0833   87 IDPAFGFAVGWNYWLNWAITVAAELTAAGIIMQYWFPDVPVWIWSLLFLALIFLLNALSVKAFGESEFWFSLIKVITVIA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 161 FLCLGLAVILGFVPGtEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRI 240
Cdd:COG0833  167 FIIVGLLMIFGIIGG-HAPGFSNFTTGDGPFPGGFLAILGVMMIVGFSFQGTELIGIAAGESENPEKTIPKAIRQVFWRI 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 241 LVFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFL 320
Cdd:COG0833  246 LLFYILAIFVIAALIPYTDAGVAESPFTLVFERAGIPYAADIMNAVILTAVLSAGNSGLYASTRMLWSLAKEGMAPKIFA 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 321 KLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMgrVEQQN----LKVKMW 396
Cdd:COG0833  326 KLNKRGVPLNALLATMAVGLLALLSSFFGAGTVYLWLLSISGLTGFIAWLGIAISHYRFRRAY--VAQGGdledLKYKAP 403

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446282268 397 FFPYVTYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKNSTVLNTKSKNEE 460
Cdd:COG0833  404 LFPFGPIFAFILCLIVIIGQAFDPEQRIALYIGIPFFLACYLGYKLKKKTKLVPLEEMDLSPED 467
PRK10197 PRK10197
GABA permease;
16-447 3.08e-117

GABA permease;


Pssm-ID: 182297  Cd Length: 446  Bit Score: 350.85  E-value: 3.08e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  16 MISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPWAGYTIGWLYWF 95
Cdd:PRK10197   1 MLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  96 FWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCLGLAVILGFVPG 175
Cdd:PRK10197  81 FWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLGAVAISGFYPY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 176 TEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFFIGSIAVVVTLL 255
Cdd:PRK10197 161 AEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALI 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 256 PWNSANILK-SPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLNSSGVPVRAVLF 334
Cdd:PRK10197 241 PWNMPGLKAvGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPYVAVLL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 335 GTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMgRVEQQNLKVKMWFFPYVTYVTIAAIIAVLI 414
Cdd:PRK10197 321 STGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKIL-RAEGSEIRLRMWLYPWLTWLVIGFITFVLV 399

                        410       420       430
                 ....*....|....*....|....*....|...
gi 446282268 415 AMLAIESLRSQALLTMLVTVLIIISYFIFNRNK 447
Cdd:PRK10197 400 VMLFRPAQQLEVISTGLLAIGIICTVPIMARWK 432
PRK10238 PRK10238
aromatic amino acid transporter AroP;
5-442 3.42e-101

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 310.35  E-value: 3.42e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPW 84
Cdd:PRK10238  10 LKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSF 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  85 AGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCL 164
Cdd:PRK10238  90 AGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAVVAMIIF 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 165 GLAVILGFVPGTEAPgTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFF 244
Cdd:PRK10238 170 GGWLLFSGNGGPQAT-VSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFY 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 245 IGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLNS 324
Cdd:PRK10238 249 IGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDK 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 325 SGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMgrvEQQNLKVKM--WFFPYVT 402
Cdd:PRK10238 329 RGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAK---QEQGVVTRFpaLLYPLGN 405

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 446282268 403 YVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFI 442
Cdd:PRK10238 406 WICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLF 445
PRK10836 PRK10836
lysine transporter; Provisional
 5-399 2.26e-99

lysine transporter; Provisional


Pssm-ID: 182767  Cd Length: 489  Bit Score: 306.75  E-value: 2.26e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPG-SIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGP 83
Cdd:PRK10836  13 LRRELKARHLTMIAIGGSIGTGLFVASGATISQAGPGgALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  84 WAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLC 163
Cdd:PRK10836  93 GFGFALGWNYWYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFSLIKVTTVIVFII 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 164 LGLAVILGFVPGTEAPGTSNL-VGQGGFMpNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILV 242
Cdd:PRK10836 173 VGVLMIIGIFKGAEPAGWSNWtIGDAPFA-GGFAAMIGVAMIVGFSFQGTELIGIAAGESEDPAKNIPRAVRQVFWRILL 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 243 FFIGSIAVVVTLLPWNSANILK--------SPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGD 314
Cdd:PRK10836 252 FYVFAILIISLIIPYTDPSLLRndvkdisvSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGK 331

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 315 APKAFLKLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKkmGRVEQ----QN 390
Cdd:PRK10836 332 APRIFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAISHYRFRR--GYVLQghdlND 409


                 ....*....
gi 446282268 391 LKVKMWFFP 399
Cdd:PRK10836 410 LPYRSGFFP 418
AA_permease pfam00324
Amino acid permease;
13-447 5.74e-96

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 296.92  E-value: 5.74e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   13 HITMISIGGVIGAGLFVGSGAVVHSAGPGS-IVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPWAGYTIGW 91
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGaLLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   92 LYWFFWVIVIAIEATAGAGIIQYW--IPEIPLW-LLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCLGLAV 168
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWelVPDIPYLwVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  169 ILGFVPGTEAPGTS--NLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFFIG 246
Cdd:pfam00324 161 LSGGNPNDGAIFRYlgDNGGKNNFPPGFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  247 SIAVVVTLLPWNSANILK------SPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFL 320
Cdd:pfam00324 241 SLLAIGLLVPWNDPGLLNdsasaaSPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  321 KLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMG--RVEQQNLKVKMWFF 398
Cdd:pfam00324 321 KVDKRGVPLRAILVSMVISLLALLLASLNPAIVFNFLLAISGLSGLIVWGLISLSHLRFRKAFKyqGRSIDELPFKAPLG 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446282268  399 PYVTYVTIAAIIAVLIAMLAIESLRS-------------QALLTMLVTVLIIISYFIFNRNK 447
Cdd:pfam00324 401 PLGVILGLAAIIIILIIQFLYAFLPVpggpknwgagsfaAAYLIVLLFLIILIGVKLHVKNW 462
PRK11387 PRK11387
S-methylmethionine permease;
5-382 1.35e-92

S-methylmethionine permease;


Pssm-ID: 236904  Cd Length: 471  Bit Score: 288.67  E-value: 1.35e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGP-GSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGP 83
Cdd:PRK11387  12 FKRTMKVRHLVMLSLGGVIGTGLFFNTGYIISTTGAaGTLLAYLIGALVVYLVMQCLGELSVAMPETGAFHVYAARYLGP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  84 WAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLC 163
Cdd:PRK11387  92 ATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQVPVWPWCLLFCALIFGLNVVSTRFFAEGEFWFSLIKVVTILAFIV 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 164 LGLAVILGFVP---GTEAPGTSNLVGQGGFmPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRI 240
Cdd:PRK11387 172 LGGAAIFGFIPmqdGSPAPGLRNLTAEGWF-PHGGLPILMTMVAVNFAFSGTELIGIAAGETENPAKVIPVAIRTTIARL 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 241 LVFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFL 320
Cdd:PRK11387 251 VIFFVGTVLVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNEGTLPACFA 330

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446282268 321 KLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKK 382
Cdd:PRK11387 331 RLTKRGIPLTALSVSMLGGLLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFMFRRR 392
PRK10746 PRK10746
putative transport protein YifK; Provisional
 3-455 1.60e-90

putative transport protein YifK; Provisional


Pssm-ID: 182694  Cd Length: 461  Bit Score: 282.86  E-value: 1.60e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   3 KNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIG 82
Cdd:PRK10746   6 PELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  83 PWAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFL 162
Cdd:PRK10746  86 PFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVMI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 163 CLGLAVIL-GFVPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRIL 241
Cdd:PRK10746 166 VIGLGVIFfGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVLWRIL 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 242 VFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLK 321
Cdd:PRK10746 246 IFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAK 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 322 LNSSGVPVRAVLFGTFFAYIGVVFSYI--SPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNlKVKMWFFP 399
Cdd:PRK10746 326 VSRHGVPVAGVAVSILILLVGSCLNYIipNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASH-PFRSILFP 404

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446282268 400 YVTYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKNSTVLNTK 455
Cdd:PRK10746 405 WANYLTMAFLICVLIGMYFNEDTRMSLFVGIIFLLAVTLIYKVFGLNRHGKAHKLE 460
PRK10249 PRK10249
phenylalanine transporter; Provisional
 5-445 7.06e-89

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 278.41  E-value: 7.06e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPW 84
Cdd:PRK10249  19 LHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPF 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  85 AGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCL 164
Cdd:PRK10249  99 AGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFALIKVLAIIGMIGF 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 165 GLAVILGFVPGTEApGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFF 244
Cdd:PRK10249 179 GLWLLFSGHGGEKA-SIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFY 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 245 IGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLNS 324
Cdd:PRK10249 258 IGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTRVSR 337

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 325 SGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRvEQQNLKVKMWFFPYVTYV 404
Cdd:PRK10249 338 RGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRFRAAMRR-QGRETQFKALLYPFGNYL 416

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 446282268 405 TIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNR 445
Cdd:PRK10249 417 CIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFVAFKTLRR 457
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 6-383 2.13e-88

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 278.01  E-value: 2.13e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268    6 KKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGP-GSIVSYALAGLLVVFVMRMLGEMAAINP-TSGSFATYAREAIGP 83
Cdd:TIGR00913   1 KKSLKQRHIQMIALGGTIGTGLLVGSGTALATGGPaGLLIGYAIMGSIIYCVMQSLGEMATFYPvVSGSFATYASRFVDP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   84 WAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLC 163
Cdd:TIGR00913  81 AFGFAVGWNYWLQWLIVLPLELVTASMTIQYWTDKVNPAVWIAIFYVFIVIINLFGVKGYGEAEFWFSSIKILAIIGFII 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  164 LGLAVILGFVPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVI----FSFMGSEIVAVAAGESAEPVKAVKTATNSVIWR 239
Cdd:TIGR00913 161 LSIILNCGGGPNHGYIGFRYWHDPGAFAGGTIGGRFKGVCSVFvtaaFSFGGTELVALTAGEAANPRKSIPRAAKRTFWR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  240 ILVFFIGSIAVVVTLLPWNSANIL---------KSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMA 310
Cdd:TIGR00913 241 ILVFYILTLFLIGFLVPYNDPRLLssssssdsaASPFVIAIQNHGIKVLPHIFNAVILISVLSAANSSLYASSRTLYALA 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446282268  311 ERGDAPKAFLKLNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKM 383
Cdd:TIGR00913 321 HQGLAPKIFAYVDRRGVPYVAVIVSSLFGLLAFLAVSKKEAEVFTWLLNISGLSGFFTWMCICLSHIRFRKAM 393
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 5-454 2.89e-88

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 277.38  E-value: 2.89e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPW 84
Cdd:PRK11049  18 LRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPW 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  85 AGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCL 164
Cdd:PRK11049  98 AGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGEMEFWFAMIKIVAIVALIVV 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 165 GLA-VILGFV-PGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILV 242
Cdd:PRK11049 178 GLVmVAMHFQsPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIM 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 243 FFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKL 322
Cdd:PRK11049 258 FYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAFAKL 337

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 323 NSSGVPVRAVLFGTFFAYIGVVFSYISPD--KVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNlKVKMWFFPY 400
Cdd:PRK11049 338 SKRAVPAKGLTFSCICLLGGVVLLYVNPSviGAFTLVTTVSAILFMFVWTIILCSYLVYRKQRPHLHEKS-IYKMPLGKL 416

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446282268 401 VTYVTiAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKNSTVLNT 454
Cdd:PRK11049 417 MCWVC-MAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELRK 469
proY PRK10580
putative proline-specific permease; Provisional
 5-395 1.06e-86

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 272.85  E-value: 1.06e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPW 84
Cdd:PRK10580   7 LKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQENLGPL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  85 AGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCL 164
Cdd:PRK10580  87 AGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIIIMIVA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 165 GLAVIL-GFVPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVF 243
Cdd:PRK10580 167 GIGIIIwGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSVPMRILVF 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 244 FIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLN 323
Cdd:PRK10580 247 YVGTLFVIMSIYPWNQVGTNGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTS 326

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446282268 324 SSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKM 395
Cdd:PRK10580 327 RRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKV 398
PRK15049 PRK15049
L-asparagine permease;
12-405 1.02e-73

L-asparagine permease;


Pssm-ID: 185009  Cd Length: 499  Bit Score: 240.29  E-value: 1.02e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  12 RHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIGPWAGYTIGW 91
Cdd:PRK15049  33 RQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGW 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  92 LYWFFWVIVIAIEATAGAGIIQYW--IPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLCLGLAVI 169
Cdd:PRK15049 113 MYFINWAMTGIVDITAVALYMHYWgaFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEFWFALIKVLAIVTFLVVGTVFL 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 170 lgfvpGTEAPGTSNLVG------QGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVF 243
Cdd:PRK15049 193 -----GSGQPLDGNTTGfhlitdNGGFFPHGLLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLF 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 244 FIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFLKLN 323
Cdd:PRK15049 268 YVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMAMGGSAPSFMAKMS 347

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 324 SSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKMWFFPYVTY 403
Cdd:PRK15049 348 RQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSW 427


                 ..
gi 446282268 404 VT 405
Cdd:PRK15049 428 LT 429
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
1-401 3.04e-49

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 173.93  E-value: 3.04e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   1 MDKNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREA 80
Cdd:COG0531    5 ESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARRA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  81 IGPWAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVL 160
Cdd:COG0531   85 LGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLLL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 161 FLCLGLAVILGFVPGTEAPGTSnlvgqggfmpnGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRI 240
Cdd:COG0531  165 FIVVGLFAFDPANFTPFLPAGG-----------GLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIV 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 241 LVFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPKAFL 320
Cdd:COG0531  234 GVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFA 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 321 KLNSS-GVPVRAVLFGTFFAYIGVVFSYISpdkvFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEqQNLKVKMWFFP 399
Cdd:COG0531  314 KVHPRfGTPVNAILLTGVIALLLLLLGAAS----FTALASLASVGVLLAYLLVALAVIVLRRRRPDLP-RPFRVPLPLIP 388


                 ..
gi 446282268 400 YV 401
Cdd:COG0531  389 IL 390
AA_permease_2 pfam13520
Amino acid permease;
15-382 1.59e-22

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 99.31  E-value: 1.59e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   15 TMISIGGVIGAGLFVGSgaVVHSAGPGSIVSYALAGLLVVFVMRM-LGEMAAINPTSGSFATYAREAIGPWAGYTIGWLY 93
Cdd:pfam13520   7 FALVIGSVIGSGIFVAP--LVASGGPALIVWGWIAAIIFSLAVGLvYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   94 WFFWVIVIAIEATAGAGIIQYWIPEI------PLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVLFLclgla 167
Cdd:pfam13520  85 WFAYVLGLASSASVAASYLLSALGPDlvpttwLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLPLILI----- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  168 VILGFVPGTEAPGTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEpvKAVKTATNSVIWRILVFFIGS 247
Cdd:pfam13520 160 IILGLVTADGGGFNLLSGEWHTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVKK--RNVPKAIFIGVIIVGVLYILV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  248 IAVVVTLLPWNSANILK---SPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAP--KAFLKL 322
Cdd:pfam13520 238 NIAFFGVVPDDEIALSSglgQVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPfsRFFAKV 317

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  323 NSSGVPVRAVLFGTFFAYIGVVFSYISPdKVFLFLVNASGGIALLVYLVIAISHLKIRKK 382
Cdd:pfam13520 318 NKFGSPIRAIILTAILSLILLLLFLLSP-AAYNALLSLSAYGYLLSYLLPIIGLLILRKK 376
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 2-389 9.19e-21

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 94.88  E-value: 9.19e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268    2 DKNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHS-AGPGSIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREA 80
Cdd:TIGR00906  23 ESKMKRCLTTWDLMALGIGSTIGAGIYVLTGEVARNdSGPAIVLSFLISGLAAVLSGFCYAEFGARVPKAGSAYLYSYVT 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   81 IGPWAGYTIGWLYWFFWVIVIAIEATAGAG----IIQYWIPEIPLWLLSLILTILLTLTNVFSV---------KSFG-EF 146
Cdd:TIGR00906 103 VGELWAFITGWNLILEYVIGTAAVARSWSAyfdeLLNKQIGQFRRTYFKLNYDGLAEYPDFFAVclilllavlLSFGvKE 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  147 EYWFSFIKVISIVLFLCLglAVILGFVPGTEAP-GTSNLVGQGGFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEP 225
Cdd:TIGR00906 183 SAWVNKIFTAINILVLLF--VIIAGFTKADVANwSITEEKGAGGFMPYGFTGVLSGAATCFFAFIGFDAIATTGEEVKNP 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  226 VKAVKTATNSVIWRILVFFIGSIAVVVTLLPWNSANIlKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRM 305
Cdd:TIGR00906 261 QRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDP-DAPFPVAFEYVGWDPAKYIVAVGALCGMSTSLLGGMFPLPRV 339

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  306 LFSMAERGDAPKAFLKLNS-SGVPVRAVlfgtffayigVVFSYISPDKVFLF----LVNASGGIALLVYLVIAISHLKIR 380
Cdd:TIGR00906 340 IYAMARDGLLFKWLAQINSkTKTPINAT----------VVSGAIAALMAFLFdlkaLVDLLSIGTLLAYSLVAACVLILR 409


                  ....*....
gi 446282268  381 KKMGRVEQQ 389
Cdd:TIGR00906 410 YQPGLVYDQ 418
2A0302 TIGR00905
transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several ...
 1-457 3.43e-12

transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129983  Cd Length: 473  Bit Score: 68.16  E-value: 3.43e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268    1 MDKNLKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPG-SIVSYALAG---LLVVFVMRMLGEMaaiNP-TSGSFAT 75
Cdd:TIGR00905   1 MSEAKSKKLGLFALTALVIGSMIGSGIFSLPQNLASVAGPGaVIIGWIITGvgmLALAFVFAILATK---KPeLDGGIYA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   76 YAREAIGPWAGYTIGWLYWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEyWFSFIKV 155
Cdd:TIGR00905  78 YAREGFGPYIGFMSGWGYWLSAWIGNVAYAVLLFSALGYFFPLFGSGNPVPSILGASVLLWVFTFLVLRGVR-QAAFINT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  156 ISIVLFLC-LGLAVILGFVPGTEAPGTSNLVGQGGFMPNGISSVLLG-ITVVIFSFMGSEiVAVAAGESAEPVKAVKTAT 233
Cdd:TIGR00905 157 ITTIAKLIpLFLFIIIGWFWFKLDLFTADFWGHDVPSLGSVFSQVKNtMLVTLWVFIGIE-GAVVSSGRAKNKSDVGKAT 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  234 nsVIWRILVffiGSIAVVVTLLPWNS------ANILKSPFVAVLEHIGIPAAAQIMNFIVLTAVLSCLNSGLYTNSRMLF 307
Cdd:TIGR00905 236 --VLGTLGA---LVIYILITLLSLGVlpqqelANLPNPSMAAVLEMIVGKWGAVLISLGLIISVLGSLLSWTMLAAEVPF 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  308 SMAERGDAPKAFLKLNSSGVPVRAVLFGTFFAYIgVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVE 387
Cdd:TIGR00905 311 SAAKDGLFPKIFGRVNKNGAPSVALLLTNILIQL-FLLLTLLTSSAYNVLVSLAVVMILVPYLLSAAYLLKLAKVGTYPK 389

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  388 QQNLKVKMWFFPYVTYVTIAAIIAVLIAMlaieslrsqaLLTMLVTVLIIISYFIFNRNKNSTVLNTKSK 457
Cdd:TIGR00905 390 IKNRKALIVGVIACVYSIWLLYAAGLKYL----------LLGFILYAPGIIFYGRARKERGKHVFNKKEI 449
frlA PRK11357
amino acid permease;
5-323 1.14e-10

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 63.34  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAGPG--SIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIG 82
Cdd:PRK11357   6 LQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPwlTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  83 PWAGYTIGWL-YWFFWVIVIAIEATAGAGIIQYWIPEIPLWLLSLILTILLT--LTNVFSVKSFGEFEYWFSFIKVISIV 159
Cdd:PRK11357  86 RPLAFLSGWAsFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAfmLLHLRSVEGGAAFQTLITIAKIIPFT 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 160 LFLCLGLAVILGFVPGteAPGTSNLVGQGGFMpngisSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWR 239
Cdd:PRK11357 166 IVIGLGIFWFKAENFA--APTTTAIGATGSFM-----ALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 240 ILVFFIGSIAVVVTLLPWNSANILKSPFVAVLEHIGI--PAAAQIMNFIVLTAVLSCLNSGLYTNSRMLFSMAERGDAPK 317
Cdd:PRK11357 239 VLVLYTLLALVISGLMPFDKLANSETPISDALTWIPAlgSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFK 318


                 ....*.
gi 446282268 318 AFLKLN 323
Cdd:PRK11357 319 CFGHVH 324
PRK10644 PRK10644
arginine/agmatine antiporter;
21-375 2.79e-10

arginine/agmatine antiporter;


Pssm-ID: 182613 [Multi-domain]  Cd Length: 445  Bit Score: 62.11  E-value: 2.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  21 GVIGAGLFV-----GSGAVVHSAGPGSIVSYALAGLLVVFVMRML-----GEMAAINPTSGSFATYAREAIGPWAGYTIG 90
Cdd:PRK10644  11 GLIPVTLMVagnimGSGVFLLPANLASTGGIAIYGWLVTIIGALGlsmvyAKMSSLDPSPGGSYAYARRCFGPFLGYQTN 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  91 WLYWFF-WVIVIAIeATAGAGIIQYWIP----EIPLWLLSLILTILLTLTNVFSVKSFGEFEYWFSFIKVISIVlflclG 165
Cdd:PRK10644  91 VLYWLAcWIGNIAM-VVIGVGYLSYFFPilkdPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALIPIV-----G 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 166 LAVILGF-VPGTEAPGTSNLVGQGGFmpNGISSVLlgiTVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFF 244
Cdd:PRK10644 165 IAVFGWFwFRGETYMAAWNVSGLGTF--GAIQSTL---NVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCY 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268 245 IGSIAVVVTLLPWNSANILKSPFV-AVLEHIGIPAAAqimnFIVLTAVLSCLNS-GLYT--NSRMLFSMAERGDAPKAFL 320
Cdd:PRK10644 240 VLSSTAIMGMIPNAALRVSASPFGdAARMALGDTAGA----IVSFCAAAGCLGSlGGWTllAGQTAKAAADDGLFPPIFA 315

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446282268 321 KLNSSGVPVRAVLFGTFFAYIgVVFSYISPD--KVFLFLVNASGGIALLVYLVIAIS 375
Cdd:PRK10644 316 RVNKAGTPVAGLLIVGVLMTI-FQLSSISPNasKEFGLVSSVSVIFTLVPYLYTCAA 371
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 5-316 6.60e-08

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 54.75  E-value: 6.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268    5 LKKDLKIRHITMISIGGVIGAGLFVGSGAVVHSAG-PG-SIVSYALAGLLVVFVMRMLGEMAAINPTSGSFATYAREAIG 82
Cdd:TIGR00911  40 LKKEITLLSGVGIIVGTIIGSGIFVSPKGVLKNAGsVGlALIMWAVCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFG 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   83 PWAGYTIgwlywfFWVIVIAIEATAGAGI-------------IQYWIPEIPLWLLSLILTILLTLTNVFSVKSFGEFEYW 149
Cdd:TIGR00911 120 PLLAFLR------LWIELLVIRPGSQAVNalnfaiyiltpvfPDCEVPEWAIRLVAVLCVLLLTLVNCLSVKWATRVQDI 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  150 FSFIKVISIVLFLCLGLAVILG-----FVPGTEAPGTSNLVGQggfmpngissVLLGITVVIFSFMGSEIVAVAAGESAE 224
Cdd:TIGR00911 194 FTACKLLALLLIIITGWVQLGKggvesLNPKNAFEGTETSAGG----------IVLAFYSGIWAYGGWNYLNFVTEEVKN 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  225 PVKAVKTAT-NSVIWRILVFFIGSIAVVVTLLPwnsANILKSPFVAVL---EHIGIpaAAQIMNFIVLTAVLSCLNSGLY 300
Cdd:TIGR00911 264 PYRTLPIAIiISMPIVTFIYVLTNIAYFTVLSP---EELLASLAVAVDfgeRLLGV--MSWAMPALVGLSCFGSVNGSLF 338

                         330
                  ....*....|....*.
gi 446282268  301 TNSRMLFSMAERGDAP 316
Cdd:TIGR00911 339 SSSRLFFVGGREGHLP 354
Spore_permease pfam03845
Spore germination protein;
9-254 4.94e-03

Spore germination protein;


Pssm-ID: 281794  Cd Length: 321  Bit Score: 38.77  E-value: 4.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268    9 LKIRHITMISIGGVIGAGLFVGSGAVVHSAGPGSIVSYALAGLLVVFVMRMLGEMAAINPtSGSFATYAREAIGPWAGYT 88
Cdd:pfam03845   2 ISTKQTFFLIVSFQLGSGILTLPRSVAEQAGPDGWISVLLAGIIGLILVYLYYYLLKKFP-EKTLIEYMKKILGKWLGSL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268   89 IGWLYWFFWVIVIAIEATAGAGIIQYW-IPEIPLWLLSLILTILL--TLTNVFSVKSFGEFEYWFSFIKVISIVLFLCLG 165
Cdd:pfam03845  81 LSILFMLYFLYIAGRVLRIFSEVIQFFlLPDTPTWIIILTLLLVSlyLISKGIEVLAREFCFIIPILLIILLLILLFSLK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446282268  166 LAVILGFVPgteapgtsnlvgqggFMPNGISSVLLGITVVIFSFMGSEIVAVAAGESAEPVKAVKTATNSVIWRILVFFI 245
Cdd:pfam03845 161 IAHIDNLRP---------------VLGNGISPVLKGLKVTSLPFGGFEILLMLYPFMKDKKKSKKAALLGVGISGLLYTL 225


                  ....*....
gi 446282268  246 GSIAVVVTL 254
Cdd:pfam03845 226 TTIIVIGVL 234
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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