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Conserved domains on  [gi|446419823|ref|WP_000497678|]
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MULTISPECIES: preprotein translocase subunit SecE [Streptococcus]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 10012948)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

CATH:  1.20.5.1030
Gene Ontology:  GO:0043952|GO:0065002|GO:0006605
SCOP:  4005885
TCDB:  3.A.5

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 2-51 3.30e-09

preprotein translocase subunit SecE; Reviewed


:

Pssm-ID: 236066  Cd Length: 64  Bit Score: 46.84  E-value: 3.30e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 446419823  2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVM 51
Cdd:PRK07597 13 FFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLIS 62
 
Name Accession Description Interval E-value
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 2-51 3.30e-09

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 46.84  E-value: 3.30e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 446419823  2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVM 51
Cdd:PRK07597 13 FFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLIS 62
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 2-55 1.18e-07

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 43.28  E-value: 1.18e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 446419823  2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVMDLIN 55
Cdd:COG0690  15 FFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 2-50 5.83e-04

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 33.56  E-value: 5.83e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 446419823   2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGV 50
Cdd:pfam00584  3 FFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILI 51
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 2-46 8.44e-03

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 30.65  E-value: 8.44e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446419823   2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLL 46
Cdd:TIGR00964  4 FFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVF 48
 
Name Accession Description Interval E-value
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 2-51 3.30e-09

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 46.84  E-value: 3.30e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 446419823  2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVM 51
Cdd:PRK07597 13 FFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLIS 62
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 2-55 1.18e-07

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 43.28  E-value: 1.18e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 446419823  2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVMDLIN 55
Cdd:COG0690  15 FFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 2-50 5.83e-04

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 33.56  E-value: 5.83e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 446419823   2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGV 50
Cdd:pfam00584  3 FFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILI 51
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 2-46 8.44e-03

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 30.65  E-value: 8.44e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446419823   2 FVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLL 46
Cdd:TIGR00964  4 FFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVF 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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