|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
1-391 |
0e+00 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 634.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVT 80
Cdd:PRK05790 1 MKDVVIVSAARTPIGKFGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQNPARQAALKAGLPVEVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRDT-VWEVLEDPIHHIMMGET 159
Cdd:PRK05790 81 ALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPHVLPGSRWGQKMGDVELVDTmIHDGLTDAFNGYHMGIT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 160 AENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKE-VVFSKDEHPRADITAEKLAGLKPAFRKDG 238
Cdd:PRK05790 161 AENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIKQRKGDpVVVDTDEHPRPDTTAESLAKLRPAFDKDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 239 SVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAF 318
Cdd:PRK05790 241 TVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADLDLIEINEAF 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446474221 319 AAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:PRK05790 321 AAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLATLCIGGGQGVALIVERP 393
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
1-391 |
0e+00 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 608.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVT 80
Cdd:COG0183 1 MREVVIVDAVRTPFGRFGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNPARQAALLAGLPESVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLqHGEIRDT-VWEVLEDPIHHIMMGET 159
Cdd:COG0183 81 AVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRM-NAKLVDPmINPGLTDPYTGLSMGET 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 160 AENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKDGS 239
Cdd:COG0183 160 AENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEVPDRKGEVVVDRDEGPRPDTTLEKLAKLKPAFKKDGT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 240 VTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFA 319
Cdd:COG0183 240 VTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLIEINEAFA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446474221 320 AQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:COG0183 320 AQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMCIGGGQGIALIIERV 391
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
5-390 |
0e+00 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 606.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 5 VITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYTI 84
Cdd:cd00751 1 VIVSAVRTPIGRFGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 85 QRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRDTVWEVLEDPIHHIMMGETAENLV 164
Cdd:cd00751 81 NRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNTLDGMLDDGLTDPFTGLSMGITAENVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 165 EQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKDGSVTAGN 244
Cdd:cd00751 161 EKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVPGRKGPVVVDRDEGPRPDTTLEKLAKLKPAFKKDGTVTAGN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 245 ASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLA 324
Cdd:cd00751 241 ASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINEAFAAQALA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446474221 325 VEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEA 390
Cdd:cd00751 321 CLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGGQGAAMVIER 386
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
6-389 |
0e+00 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 524.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 6 ITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYTIQ 85
Cdd:TIGR01930 1 IVAAARTPIGKFGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTVN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 86 RQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQ-HRWGQRLQHGEIRDTVWEVLEDPIHHIMMGETAENLV 164
Cdd:TIGR01930 81 RQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVPRsLRWGVKPGNAELEDARLKDLTDANTGLPMGVTAENLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 165 EQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKDGSVTAGN 244
Cdd:TIGR01930 161 KKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKGRKGPVTVSSDEGIRPNTTLEKLAKLKPAFDPDGTVTAGN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 245 ASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLA 324
Cdd:TIGR01930 241 SSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEAFAAQVLA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446474221 325 VEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIE 389
Cdd:TIGR01930 321 CIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGGQGAAVILE 385
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
1-391 |
9.67e-179 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 502.57 E-value: 9.67e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQrTD--EANTARTAALAAGFPDT 78
Cdd:PRK09051 2 MREVVVVSGVRTAIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIP-TEprDMYLSRVAAINAGVPQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 79 VTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRDTVWEVLEDPIHHIMMGE 158
Cdd:PRK09051 81 TPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLPAARWGARMGDAKLVDMMVGALHDPFGTIHMGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 159 TAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKD- 237
Cdd:PRK09051 161 TAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVEIKTRKGEVVFDTDEHVRADTTLEDLAKLKPVFKKEn 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 238 GSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEA 317
Cdd:PRK09051 241 GTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVADLDVIEANEA 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446474221 318 FAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:PRK09051 321 FAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMCIGGGQGIAAIFERL 394
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
1-390 |
1.11e-158 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 452.13 E-value: 1.11e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVT 80
Cdd:PRK06205 1 MRDAVICEPVRTPVGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIGRVAALDAGLPVTVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRDTVWE--VLEDPIHHIM--- 155
Cdd:PRK06205 81 GMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFYTTDMRWGVRGGGVQLHDRLARgrETAGGRRFPVpgg 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 156 MGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKE-VVFSKDEHPRADITAEKLAGLKPAF 234
Cdd:PRK06205 161 MIETAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTVPQRKGDpTVVDRDEHPRADTTLESLAKLRPIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 235 RK---DGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADL 311
Cdd:PRK06205 241 GKqdpEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGLTLDDIDL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 312 LEINEAFAAQYLAVEKELGL---DREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFI 388
Cdd:PRK06205 321 IELNEAFAAQVLAVLKEWGFgadDEERLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETMCIGGGQGLAAVF 400
|
..
gi 446474221 389 EA 390
Cdd:PRK06205 401 ER 402
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
1-389 |
1.58e-145 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 418.14 E-value: 1.58e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVT 80
Cdd:PRK05656 1 MQDVVIVAATRTAIGSFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRDT-----VWEVLEDpiHHim 155
Cdd:PRK05656 81 AMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYVLPGARTGLRMGHAQLVDSmitdgLWDAFND--YH-- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 156 MGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKE-VVFSKDEHPRADITAEKLAGLKPAF 234
Cdd:PRK05656 157 MGITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPILIPQRKGEpLAFATDEQPRAGTTAESLAKLKPAF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 235 RKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEI 314
Cdd:PRK05656 237 KKDGSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEA 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446474221 315 NEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIE 389
Cdd:PRK05656 317 NEAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALAIE 391
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
1-389 |
2.73e-141 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 407.56 E-value: 2.73e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVT 80
Cdd:PRK08235 1 MSKTVIVSAARTPFGKFGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRD-TVWEVLEDPIHHIMMGET 159
Cdd:PRK08235 81 TETVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPYILPGARWGYRMGDNEVIDlMVADGLTCAFSGVHMGVY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 160 AENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERR-KEVVFSKDEHPRADITAEKLAGLKPAFRKDG 238
Cdd:PRK08235 161 GGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTIPQRKgDPIVVAKDEAPRKDTTIEKLAKLKPVFDKTG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 239 SVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAF 318
Cdd:PRK08235 241 TITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDIDLFEINEAF 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446474221 319 AAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIE 389
Cdd:PRK08235 321 AAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAICSGGGQGDAVLIE 391
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
1-389 |
1.07e-138 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 401.25 E-value: 1.07e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVEL-AVPVLQEAVKRGGVEPHEVDEVILGHCIQR-TDEANTARTAALAAGFPDT 78
Cdd:PRK09050 1 MTEAFICDAIRTPIGRYGGALSSVRADDLgAVPLKALMARNPGVDWEAVDDVIYGCANQAgEDNRNVARMSALLAGLPVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 79 VTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYAL-KQHRWGQRlqHGEIRDTV--WEVLeDPIHHIM 155
Cdd:PRK09050 81 VPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAPFVMgKADSAFSR--QAEIFDTTigWRFV-NPLMKAQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 156 -----MGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKE-VVFSKDEHPRADITAEKLAG 229
Cdd:PRK09050 158 ygvdsMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTIPQKKGDpVVVDRDEHPRPETTLEALAK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 230 LKPAFRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDA 309
Cdd:PRK09050 238 LKPVFRPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPATRKLLARLGLTIDQF 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 310 DLLEINEAFAAQYLAVEKELGL--DREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALF 387
Cdd:PRK09050 318 DVIELNEAFAAQGLAVLRQLGLadDDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGRYALCTMCIGVGQGIALA 397
|
..
gi 446474221 388 IE 389
Cdd:PRK09050 398 IE 399
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
3-391 |
4.95e-128 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 373.66 E-value: 4.95e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 3 NVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGY 82
Cdd:PLN02644 2 DVCIVGVARTPIGGFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSANLGQAPARQAALGAGLPPSTICT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 83 TIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRD-TVWEVLEDPIHHIMMGETAE 161
Cdd:PLN02644 82 TVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKYLPEARKGSRLGHDTVVDgMLKDGLWDVYNDFGMGVCAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 162 NLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITI--KERRKEVVFSKDEHPrADITAEKLAGLKPAFRKD-G 238
Cdd:PLN02644 162 LCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVpgGRGRPSVIVDKDEGL-GKFDPAKLRKLRPSFKEDgG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 239 SVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAF 318
Cdd:PLN02644 241 SVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLEASQVDYYEINEAF 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446474221 319 AAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:PLN02644 321 SVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGICNGGGGASAIVVELM 393
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
1-391 |
2.29e-126 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 369.46 E-value: 2.29e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFG-GALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEA-NTARTAALAAGFPDT 78
Cdd:PRK07661 1 MREAVIVAGARTPVGKAKkGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGlNMARNIGALAGLPYT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 79 VTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPyaLKQHrwgqrlqhgEIRDTVWEVLEDPIHHIMMGE 158
Cdd:PRK07661 81 VPAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVP--MMGH---------VVRPNPRLVEAAPEYYMGMGH 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 159 TAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERR---------KEVVFSKDEHPRADITAEKLAG 229
Cdd:PRK07661 150 TAEQVAVKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVPVDVTLRTvgennklqeETITFSQDEGVRADTTLEILGK 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 230 LKPAFRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDA 309
Cdd:PRK07661 230 LRPAFNVKGSVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDI 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 310 DLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIE 389
Cdd:PRK07661 310 GLFELNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFE 389
|
..
gi 446474221 390 AL 391
Cdd:PRK07661 390 LL 391
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
1-391 |
1.09e-125 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 368.18 E-value: 1.09e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTF-GGALKNVTPVELAVPVLQEAVKR-GGVEPHEVDEVILGHCIQRTDEA-NTARTAALAAGFPD 77
Cdd:PRK09052 5 LQDAYIVAATRTPVGKApRGMFKNTRPDDLLAHVLRSAVAQvPGLDPKLIEDAIVGCAMPEAEQGlNVARIGALLAGLPN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 78 TVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSP-----YALKQHrwgqrlqhgeirdtVWEVLEDPIH 152
Cdd:PRK09052 85 SVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPmmgnkPSMSPA--------------IFARDENVGI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 153 HIMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERR----------KEVVFSKDEHPRADI 222
Cdd:PRK09052 151 AYGMGLTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYEITERFpdlatgevdvKTRTVDLDEGPRADT 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 223 TAEKLAGLKPAFRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKV 302
Cdd:PRK09052 231 SLEGLAKLKPVFANKGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAALKQA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 303 DWSLEDADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGI 382
Cdd:PRK09052 311 GLKQDDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMVTMCVGTGM 390
|
....*....
gi 446474221 383 GVALFIEAL 391
Cdd:PRK09052 391 GAAGIFERL 399
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
1-391 |
1.31e-125 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 368.18 E-value: 1.31e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIG-TFGGALKNVTPVELAVPVLQEAV-KRGGVEPHEVDEVILGhCIQRTDEA--NTARTAALAAGFp 76
Cdd:PRK07851 1 MPEAVIVSTARSPIGrAFKGSLKDMRPDDLAAQMVRAALdKVPALDPTDIDDLMLG-CGLPGGEQgfNMARVVAVLLGY- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 77 DTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSP--------------YALKQHRWGQRLQHGeirDT 142
Cdd:PRK07851 79 DFLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRFAkgnsdslpdtknplFAEAQARTAARAEGG---AE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 143 VW----EVLEDPIHHIMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKErrkEVVFSKDEHP 218
Cdd:PRK07851 156 AWhdprEDGLLPDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLPD---GTVVSTDDGP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 219 RADITAEKLAGLKPAFRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKG 298
Cdd:PRK07851 233 RAGTTYEKVSQLKPVFRPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPVEASKQA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 299 LEKVDWSLEDADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCV 378
Cdd:PRK07851 313 LARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKTFGLETMCV 392
|
410
....*....|...
gi 446474221 379 GGGIGVALFIEAL 391
Cdd:PRK07851 393 GGGQGMAMVLERL 405
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
3-390 |
1.75e-124 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 366.78 E-value: 1.75e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 3 NVVITAAVRSPI-GTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCI----QRtdeANTARTAALAAGFPD 77
Cdd:PLN02287 47 DVVIVAAYRTPIcKAKRGGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLapgsQR---ANECRMAAFYAGFPE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 78 TVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRDTVwevledpihhIMMG 157
Cdd:PLN02287 124 TVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGGVNPRVESFSQAQDCL----------LPMG 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 158 ETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIK------ERRKEVVFSKDEHPRADITAEKLAGLK 231
Cdd:PLN02287 194 ITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKivdpktGEEKPIVISVDDGIRPNTTLADLAKLK 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 232 PAFRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADL 311
Cdd:PLN02287 274 PVFKKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLELDDIDL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 312 LEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEK--GIASLCVGGGIGVALFIE 389
Cdd:PLN02287 354 FEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGKDCrfGVVSMCIGTGMGAAAVFE 433
|
.
gi 446474221 390 A 390
Cdd:PLN02287 434 R 434
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
4-391 |
2.35e-121 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 356.65 E-value: 2.35e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 4 VVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYT 83
Cdd:PRK06633 5 VYITHAKRTAFGSFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVPGYT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 84 IQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSsspyaLKQH----RWGQRLQHGEIRDTV-WEVLEDPIHHIMMGE 158
Cdd:PRK06633 85 INKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMS-----LGMHgsyiRAGAKFGDIKMVDLMqYDGLTDVFSGVFMGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 159 TAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKDG 238
Cdd:PRK06633 160 TAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEVTIKKTTSLFDHDETVRPDTSLEILSKLRPAFDKNG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 239 SVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAF 318
Cdd:PRK06633 240 VVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVNEAF 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446474221 319 AAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:PRK06633 320 AAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCIGGGMGMAMCVEAV 392
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
1-389 |
4.43e-119 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 350.95 E-value: 4.43e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFG------GALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGhCIQRTDEANT--ARTAALA 72
Cdd:PRK06445 1 LEDVYLVDFARTAFSRFRpkdpqkDVFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITG-CALQVGENWLygGRHPIFL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 73 AGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYalkqhrwgQRLQHGEIRDTVwevLEDP-- 150
Cdd:PRK06445 80 ARLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPM--------GDNPHIEPNPKL---LTDPky 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 151 IHHIM-----MGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRADITAE 225
Cdd:PRK06445 149 IEYDLttgyvMGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEVEGKKKVVDVDQSVRPDTSLE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 226 KLAGLKPAFRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWS 305
Cdd:PRK06445 229 KLAKLPPAFKPDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLS 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 306 LEDADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVA 385
Cdd:PRK06445 309 VKDIDLWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVATLCVGGGQGGA 388
|
....
gi 446474221 386 LFIE 389
Cdd:PRK06445 389 VVLE 392
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
1-389 |
1.66e-117 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 346.57 E-value: 1.66e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIG-TFGGALKNVTPVELAVPVLQEAVKRG-GVEPHEVDEVILGhCIQRTDEA--NTARTAALAAGFP 76
Cdd:PRK08947 1 MEDVVIVDAIRTPMGrSKGGAFRNVRAEDLSAHLMRSLLARNpALDPAEIDDIIWG-CVQQTLEQgfNIARNAALLAGIP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 77 DTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPyalkqhrwgqrLQHGeirdtvweVLEDP--IHHI 154
Cdd:PRK08947 80 HSVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVP-----------MNHG--------VDFHPglSKNV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 155 -----MMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPItikERRKE----VVFSKDEHPRADITAE 225
Cdd:PRK08947 141 akaagMMGLTAEMLGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPT---EGHDAdgvlKLFDYDEVIRPETTVE 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 226 KLAGLKPAFR-KDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDW 304
Cdd:PRK08947 218 ALAALRPAFDpVNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 305 SLEDADLLEINEAFAAQYLAVEKELGL-DR--EKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGG 381
Cdd:PRK08947 298 SISDIDVFELNEAFAAQSLPCLKDLGLlDKmdEKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCIGLG 377
|
....*...
gi 446474221 382 IGVALFIE 389
Cdd:PRK08947 378 QGIATVFE 385
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
1-391 |
3.89e-114 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 339.69 E-value: 3.89e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVT 80
Cdd:PRK08170 2 ARPVYIVDGARTPFLKARGGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDEANIARVVALRLGCGEKVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQH--RW----------GQRLQH-GEIRD------ 141
Cdd:PRK08170 82 AWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPLLFSEKmvRWlagwyaaksiGQKLAAlGKLRPsylapv 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 142 -TVWEVLEDPIHHIMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDdQIVPITikeRRKEVVFSKDEHPRA 220
Cdd:PRK08170 162 iGLLRGLTDPVVGLNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLK-EVVPLF---DRDGKFYDHDDGVRP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 221 DITAEKLAGLKPAF-RKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGL 299
Cdd:PRK08170 238 DSSMEKLAKLKPFFdRPYGRVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPVHAATPLL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 300 EKVDWSLEDADLLEINEAFAAQYLA----------------VEKELG-LDREKVNVNGSGVGLGHPIGCTGARITVSLIH 362
Cdd:PRK08170 318 QRHGLTLEDLDLWEINEAFAAQVLAclaawadeeycreqlgLDGALGeLDRERLNVDGGAIALGHPVGASGARIVLHLLH 397
|
410 420
....*....|....*....|....*....
gi 446474221 363 ELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:PRK08170 398 ALKRRGTKRGIAAICIGGGQGGAMLLERV 426
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
4-389 |
6.07e-111 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 330.32 E-value: 6.07e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 4 VVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYT 83
Cdd:PRK06954 9 IVIASAARTPMAAFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAPARQAALGAGLPLSVGCTT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 84 IQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRDTVW-EVLEDPIHH-IMMGETAE 161
Cdd:PRK06954 89 VNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPYLLPKARGGMRMGHGQVLDHMFlDGLEDAYDKgRLMGTFAE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 162 NLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRAdITAEKLAGLKPAFRKDGSVT 241
Cdd:PRK06954 169 ECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVTVAGKKGDTVIDRDEQPFK-ANPEKIPTLKPAFSKTGTVT 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 242 AGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFAAQ 321
Cdd:PRK06954 248 AANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFEINEAFAVV 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446474221 322 YLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIE 389
Cdd:PRK06954 328 TMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCIGGGEATAMGIE 395
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
1-391 |
1.71e-105 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 315.88 E-value: 1.71e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEA-NTARTAALAAGFPDTV 79
Cdd:PRK07801 1 MAEAYIVDAVRTPVGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIGPQAgNIARTSWLAAGLPEEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 80 TGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMS----------------SSPYALKQHrWGQRLQHGEIRDTV 143
Cdd:PRK07801 81 PGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSqipissamtageqlgfTSPFAESKG-WLHRYGDQEVSQFR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 144 wevledpihhimmgeTAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITikerrkevVFSKDEHPRaDIT 223
Cdd:PRK07801 160 ---------------GAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVG--------GVTVDEGPR-ETS 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 224 AEKLAGLKPaFRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVD 303
Cdd:PRK07801 216 LEKMAGLKP-LVEGGRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTG 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 304 WSLEDADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIG 383
Cdd:PRK07801 295 LSIDDIDVVEINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMCEGGGTA 374
|
....*...
gi 446474221 384 VALFIEAL 391
Cdd:PRK07801 375 NVTIIERL 382
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
1-389 |
2.35e-105 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 316.05 E-value: 2.35e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTF--GGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGhCIQRTDE--ANTARTAALAAGFP 76
Cdd:PRK08242 1 MTEAYIYDAVRTPRGKGkkDGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLG-CVTPVGDqgADIARTAVLAAGLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 77 DTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQrlqhgeirdtvwevleDP-----I 151
Cdd:PRK08242 80 ETVPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVPMGSDGGAWAM----------------DPstnfpT 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 152 HHIMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPItiKERRKEVVFSKDEHPRADITAEKLAGLK 231
Cdd:PRK08242 144 YFVPQGISADLIATKYGFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPV--KDQNGLTILDHDEHMRPGTTMESLAKLK 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 232 PAFRKDGSV---------------------TAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIG 290
Cdd:PRK08242 222 PSFAMMGEMggfdavalqkypeverinhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTG 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 291 PAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLE 370
Cdd:PRK08242 302 PVPATRKALAKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKR 381
|
410
....*....|....*....
gi 446474221 371 KGIASLCVGGGIGVALFIE 389
Cdd:PRK08242 382 TALITLCVGGGMGIATIIE 400
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
1-389 |
6.73e-104 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 312.48 E-value: 6.73e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQR-TDEANTARTAALAAGFPDTV 79
Cdd:PRK08131 1 MLDAYIYDGLRSPFGRHAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAgEDSRNVARNALLLAGLPVTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 80 TGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYAL--KQHRWGQRLqhgEIRDTVW-------EVLEDP 150
Cdd:PRK08131 81 PGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPFVMgkAESAFSRDA---KVFDTTIgarfpnpKIVAQY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 151 IHHiMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRK--EVVFSKDEHPRADITAEKLA 228
Cdd:PRK08131 158 GND-SMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGRKlpPKLVAEDEHPRPSSTVEALT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 229 GLKPAFrKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLED 308
Cdd:PRK08131 237 KLKPLF-EGGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLDD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 309 ADLLEINEAFAAQYLAVEKELGL--DREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVAL 386
Cdd:PRK08131 316 MDIIEINEAFASQVLGCLKGLGVdfDDPRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKRYAVVSLCIGVGQGLAM 395
|
...
gi 446474221 387 FIE 389
Cdd:PRK08131 396 VIE 398
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
4-261 |
1.46e-102 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 303.84 E-value: 1.46e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 4 VVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYT 83
Cdd:pfam00108 1 VVIVSAARTPFGSFGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 84 IQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQH-RWGQRLQHGEIRD-TVWEVLEDPIHHIMMGETAE 161
Cdd:pfam00108 81 INKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDaRSGLKHGDEKKHDlLIPDGLTDAFNGYHMGLTAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 162 NLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKDGSVT 241
Cdd:pfam00108 161 NVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGRKGKPTVDKDEGIRPPTTAEPLAKLKPAFDKEGTVT 240
|
250 260
....*....|....*....|
gi 446474221 242 AGNASGLNDGSAVLVLMSEE 261
Cdd:pfam00108 241 AGNASPINDGAAAVLLMSES 260
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
1-389 |
2.62e-100 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 303.08 E-value: 2.62e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVT 80
Cdd:PRK06366 1 MKDVYIVSAKRTAIGKFGRSFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQAAYHAGLPFGVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQH-RWG-QRLQHG--EIRDTVW-EVLEDPIHHIM 155
Cdd:PRK06366 81 KYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPFLLPSDlRWGpKHLLHKnyKIDDAMLvDGLIDAFYFEH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 156 MGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITikerrkevVFSKDEHPRaDITAEKLAGLKPAFR 235
Cdd:PRK06366 161 MGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFN--------DLDRDEGIR-KTTMEDLAKLPPAFD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 236 KDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEIN 315
Cdd:PRK06366 232 KNGILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQNKSIDYYDLVEHN 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446474221 316 EAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIE 389
Cdd:PRK06366 312 EAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTGLATLCHGGGGAHTLTLE 385
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
1-391 |
1.24e-97 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 296.30 E-value: 1.24e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIG-TFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGhCI--QRTDEANTARTAALAAGFPD 77
Cdd:PRK07108 1 MTEAVIVSTARTPLAkSWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMG-CAnpEGATGANIARQIALRAGLPV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 78 TVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRwgqrLQHGeirdtvWEVLEDPIHHIMMG 157
Cdd:PRK07108 80 TVPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCVQNEMNRHM----LREG------WLVEHKPEIYWSML 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 158 ETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKE----------RRKEVVFSKDEHPRADITAEKL 227
Cdd:PRK07108 150 QTAENVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTAgvadkatgrlFTKEVTVSADEGIRPDTTLEGV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 228 AGLKPAFrKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLE 307
Cdd:PRK07108 230 SKIRSAL-PGGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVD 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 308 DADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALF 387
Cdd:PRK07108 309 DIDLWELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCIGGGQGAAGL 388
|
....
gi 446474221 388 IEAL 391
Cdd:PRK07108 389 FEVL 392
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
3-391 |
1.00e-96 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 292.83 E-value: 1.00e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 3 NVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKrgGVEpHEVDEVILGHCIQRTdeANTARTAALAAGFPDTVTGY 82
Cdd:PRK06690 2 RAVIVEAKRTPIGKKNGMLKDYEVQQLAAPLLTFLSK--GME-REIDDVILGNVVGPG--GNVARLSALEAGLGLHIPGV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 83 TIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYAlKQHRWGQrlqhgeirdtvwEVLEDPihhiMMGETAEN 162
Cdd:PRK06690 77 TIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQ-NRARFSP------------ETIGDP----DMGVAAEY 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 163 LVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPIT-------IKERRKEVVFSKdehpraditaeklagLKPAFR 235
Cdd:PRK06690 140 VAERYNITREMQDEYACLSYKRTLQALEKGYIHEEILSFNglldesiKKEMNYERIIKR---------------TKPAFL 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 236 KDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEIN 315
Cdd:PRK06690 205 HNGTVTAGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEIN 284
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446474221 316 EAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:PRK06690 285 EAFASKVVACAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLALLFEKV 360
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
4-390 |
5.14e-94 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 288.04 E-value: 5.14e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 4 VVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYT 83
Cdd:PRK08963 7 IAIVSGLRTPFAKQATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 84 IQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYAL------------KQHRWGQRL---QHGEIRD--TVWEV 146
Cdd:PRK08963 87 VSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGVskklaralvdlnKARTLGQRLklfSRLRLRDllPVPPA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 147 LEDPIHHIMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKevVFSKDEHPRADITAEK 226
Cdd:PRK08963 167 VAEYSTGLRMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVMTAHVPPYKQ--PLEEDNNIRGDSTLED 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 227 LAGLKPAF-RKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDP-KIMGIGPAPAIRKGLEKVDW 304
Cdd:PRK08963 245 YAKLRPAFdRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVwQDMLLGPAYATPLALERAGL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 305 SLEDADLLEINEAFAAQYLA----------VEKELG-------LDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRR 367
Cdd:PRK08963 325 TLADLTLIDMHEAFAAQTLAnlqmfaserfAREKLGrsqaigeVDMSKFNVLGGSIAYGHPFAATGARMITQTLHELRRR 404
|
410 420
....*....|....*....|...
gi 446474221 368 GLEKGIASLCVGGGIGVALFIEA 390
Cdd:PRK08963 405 GGGLGLTTACAAGGLGAAMVLEV 427
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
1-389 |
6.29e-91 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 278.91 E-value: 6.29e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVIlGHCIQRTDEA--NTARTAALAAGFPDT 78
Cdd:PRK07850 1 MGNPVIVEAVRTPIGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVI-GGCVTQAGEQsnNITRTAWLHAGLPYH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 79 VTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSP--YALKQHRwgqrlqhGEIRDTVWEvLEDPIHHimm 156
Cdd:PRK07850 80 VGATTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPlgANAGPGR-------GLPRPDSWD-IDMPNQF--- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 157 gETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKE-------VVFSKDEHPRaDITAEKLAG 229
Cdd:PRK07850 149 -EAAERIAKRRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEEgqptgetRLVTRDQGLR-DTTMEGLAG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 230 LKPAfRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDA 309
Cdd:PRK07850 227 LKPV-LEGGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDI 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 310 DLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIE 389
Cdd:PRK07850 306 DLVEINEAFASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAGGALSTGTIIE 385
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
1-391 |
4.26e-89 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 274.30 E-value: 4.26e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGhCIQRTDE--ANTARTAALAAGFPDT 78
Cdd:PRK06504 1 MAEAYIVAAARTAGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMG-CVSQVGEqaTNVARNAVLASKLPES 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 79 VTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKqhrwGQRLQHGEIRDTVWEVLEDPIHHIM--- 155
Cdd:PRK06504 80 VPGTSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSP----STLPAKNGLGHYKSPGMEERYPGIQfsq 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 156 -MGetAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSK-DEHPRADITAEKLAGLKPa 233
Cdd:PRK06504 156 fTG--AEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEITRADGSGEMHTvDEGIRFDATLEGIAGVKL- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 234 FRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLE 313
Cdd:PRK06504 233 IAEGGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDLYE 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446474221 314 INEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEAL 391
Cdd:PRK06504 313 VNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMCEGGGMANVTIVERL 390
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
1-389 |
8.32e-84 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 261.63 E-value: 8.32e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSP--IGTFG-GALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEA-NTARTAALAAGFP 76
Cdd:PRK06025 1 MAEAYIIDAVRTPrgIGKVGkGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKQGgDLGRMAALDAGYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 77 DTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMS-SSPYALKQHRWGQ---RLQHGEIRDTVwevlEDPIH 152
Cdd:PRK06025 81 IKASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSyTAAMAAEDMAAGKpplGMGSGNLRLRA----LHPQS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 153 HimMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRkeVVFSKDEHPRADITAEKLAGLKP 232
Cdd:PRK06025 157 H--QGVCGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVYRDDGS--VALDHEEFPRPQTTAEGLAALKP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 233 AFRK-------DGSVT-------------------AGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKI 286
Cdd:PRK06025 233 AFTAiadypldDKGTTyrglinqkypdleikhvhhAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 287 MGIGPAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGARITVSLIHELKR 366
Cdd:PRK06025 313 MLNAPVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELER 392
|
410 420
....*....|....*....|...
gi 446474221 367 RGLEKGIASLCVGGGIGVALFIE 389
Cdd:PRK06025 393 RGLKRGLVTMCAAGGMAPAIIIE 415
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
4-390 |
3.55e-74 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 237.11 E-value: 3.55e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 4 VVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYT 83
Cdd:PRK09268 9 VAILGGNRIPFARSNGAYADASNQDMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNLTRECVLGSALSPYTPAYD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 84 IQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYAL-KQHRW-----------GQRLQH-GEIR--DTVWEV-- 146
Cdd:PRK09268 89 LQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTSDAPIAVnEGLRKillelnrakttGDRLKAlGKLRpkHLAPEIpr 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 147 LEDPIHHIMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERrkevvfskDEHPRADITAEK 226
Cdd:PRK09268 169 NGEPRTGLSMGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPFLGLTR--------DNNLRPDSSLEK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 227 LAGLKPAFRK--DGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVD----PKIMGIGPAPAIRKGLE 300
Cdd:PRK09268 241 LAKLKPVFGKggRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAAVDfvhgKEGLLMAPAYAVPRLLA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 301 KVDWSLEDADLLEINEAFAAQYLAVEK----------ELGL-------DREKVNVNGSGVGLGHPIGCTGARITVSLIHE 363
Cdd:PRK09268 321 RNGLTLQDFDFYEIHEAFASQVLATLKawedeeycreRLGLdaplgsiDRSKLNVNGSSLAAGHPFAATGGRIVATLAKL 400
|
410 420
....*....|....*....|....*..
gi 446474221 364 LKRRGLEKGIASLCVGGGIGVALFIEA 390
Cdd:PRK09268 401 LAEKGSGRGLISICAAGGQGVTAILER 427
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
8-389 |
3.50e-68 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 220.44 E-value: 3.50e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 8 AAVRSPIGTFGG---ALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTGYTI 84
Cdd:cd00826 2 GAAMTAFGKFGGengADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 85 QRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHrwgqrlqhgeirdtvWEVledpihhimmgetaENLV 164
Cdd:cd00826 82 NNLCGSGLRALALAMQLIAGGDANCILAGGFEKMETSAENNAKE---------------KHI--------------DVLI 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 165 EQYEiTREEQDEVALRSHTLALKAIESGHFDDQIVPITIKERRKEVVFSKDEHPR--ADITAEKLAGLKPAFRKDGSVTA 242
Cdd:cd00826 133 NKYG-MRACPDAFALAGQAGAEAAEKDGRFKDEFAKFGVKGRKGDIHSDADEYIQfgDEASLDEIAKLRPAFDKEDFLTA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 243 GNASGLNDGSAVLVLMSEEKA-------KEKGLQPLARIVGYSVAGVDPK----IMGIGPAPAIRKGLEKVDWSLEDADL 311
Cdd:cd00826 212 GNACGLNDGAAAAILMSEAEAqkhglqsKAREIQALEMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 312 LEINEAFAAQYLAVEKELGLDREK------------------VNVNGSGVGLGHPIGCTGARITVSLIHELKRR-----G 368
Cdd:cd00826 292 IEAHDAFAANACATNEALGLCPEGqggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEagkrqG 371
|
410 420
....*....|....*....|.
gi 446474221 369 LEKGIASLCVGGGIGVALFIE 389
Cdd:cd00826 372 AGAGLALLCIGGGGGAAMCIE 392
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
268-390 |
8.55e-61 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 192.09 E-value: 8.55e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 268 LQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELGLDREKVNVNGSGVGLGH 347
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 446474221 348 PIGCTGARITVSLIHELKRRGLEKGIASLCVGGGIGVALFIEA 390
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIER 123
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
242-388 |
4.52e-24 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 99.83 E-value: 4.52e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 242 AGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSV----AGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEA 317
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAAtfdgASMVPAVSGEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 318 FAAQYLAVEKELGLDREKVNVNGSGVGL---GHPIGCTGARITVSLIHELK-------RRGLEKGIASLCVGGGIGVALF 387
Cdd:cd00327 174 GTPIGDAVELALGLDPDGVRSPAVSATLimtGHPLGAAGLAILDELLLMLEhefipptPREPRTVLLLGFGLGGTNAAVV 253
|
.
gi 446474221 388 I 388
Cdd:cd00327 254 L 254
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
23-367 |
8.13e-22 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 95.79 E-value: 8.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 23 NVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDTVTgYTIQRQCSSGMQAIMSAAMQI 102
Cdd:cd00829 13 DRSPLELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLLGKPA-TRVEAAGASGSAAVRAAAAAI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 103 QLGVSDVVVAGGVEAMSSSPYAlkqHRWGQRLQHGEIRDtvWEVLEDPIHHIMMGETAENLVEQYEITREEQDEVALRSH 182
Cdd:cd00829 92 ASGLADVVLVVGAEKMSDVPTG---DEAGGRASDLEWEG--PEPPGGLTPPALYALAARRYMHRYGTTREDLAKVAVKNH 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 183 TLALKaiesghfddqivpitikerrkevvfskdeHPRA----DITAEKLAGLKPAFrkdGSVTAGNASGLNDGSAVLVLM 258
Cdd:cd00829 167 RNAAR-----------------------------NPYAqfrkPITVEDVLNSRMIA---DPLRLLDCCPVSDGAAAVVLA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 259 SEEKAKEKGLQPlARIVG-------YSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFA-AQYLAVEkELG 330
Cdd:cd00829 215 SEERARELTDRP-VWILGvgaasdtPSLSERDDFLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTiAELLALE-DLG 292
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 446474221 331 LDRE------------------KVNVNGSGVGLGHPIGCTGARITVSLIHELKRR 367
Cdd:cd00829 293 FCEKgeggklvregdtaiggdlPVNTSGGLLSKGHPLGATGLAQAVEAVRQLRGE 347
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
19-367 |
2.34e-11 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 64.87 E-value: 2.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 19 GALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFpdtvTGYT---IQRQCSSGMQAI 95
Cdd:PRK12578 14 GRRDDVSVQELAWESIKEALNDAGVSQTDIELVVVGSTAYRGIELYPAPIVAEYSGL----TGKVplrVEAMCATGLAAS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 96 MSAAMQIQLGVSDVVVAGGVEAMS-------------SSPYALKQHRWGQRLqhgeirdtvwevledPIHHIMMgetAEN 162
Cdd:PRK12578 90 LTAYTAVASGLVDMAIAVGVDKMTevdtstslaiggrGGNYQWEYHFYGTTF---------------PTYYALY---ATR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 163 LVEQYEITREEQDEVALRSHTLALKAiESGHFDDqivPITIKERRKEVVFSkdeHPraditaeklaglkpafrkdgsVTA 242
Cdd:PRK12578 152 HMAVYGTTEEQMALVSVKAHKYGAMN-PKAHFQK---PVTVEEVLKSRAIS---WP---------------------IKL 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 243 GNASGLNDGSAVLVLMSEEKAKEKGLQPLARI--VGYS--VAGVDPKIMGIG---PAPAIRKGLEKVDWSLEDADLLEIN 315
Cdd:PRK12578 204 LDSCPISDGSATAIFASEEKVKELKIDSPVWItgIGYAndYAYVARRGEWVGfkaTQLAARQAYNMAKVTPNDIEVATVH 283
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446474221 316 EAFA-AQYLAVEkELGLDRE----------------KVNVNGSGvGL---GHPIGCTGaritVSLIHELKRR 367
Cdd:PRK12578 284 DAFTiAEIMGYE-DLGFTEKgkggkfieegqsekggKVGVNLFG-GLkakGHPLGATG----LSMIYEITKQ 349
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
1-385 |
2.19e-10 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 61.84 E-value: 2.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTfggaLKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCI--QRTDEANTARTAALAAGFPDt 78
Cdd:PRK06064 1 MRDVAIIGVGQTKFGE----LWDVSLRDLAVEAGLEALEDAGIDGKDIDAMYVGNMSagLFVSQEHIAALIADYAGLAP- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 79 VTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPY-----ALkqhrwgqrlqhGEIRDTVWEVledpihh 153
Cdd:PRK06064 76 IPATRVEAACASGGAALRQAYLAVASGEADVVLAAGVEKMTDVPTpdateAI-----------ARAGDYEWEE------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 154 iMMGET--------AENLVEQYEITREEQDEVALRSHtlalkaiESGHFDdqivPITikERRKEVvfSKDEHPRADITAE 225
Cdd:PRK06064 138 -FFGATfpglyaliARRYMHKYGTTEEDLALVAVKNH-------YNGSKN----PYA--QFQKEI--TVEQVLNSPPVAD 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 226 KLAGLkpafrkdgsvtagNASGLNDGSAVLVLMSEEKAKEKGLQPLaRIVGYSVAGvD-------PKIMGIGPAP-AIRK 297
Cdd:PRK06064 202 PLKLL-------------DCSPITDGAAAVILASEEKAKEYTDTPV-WIKASGQAS-DtialhdrKDFTTLDAAVvAAEK 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 298 GLEKVDWSLEDADLLEINEAFA-AQYLAVEkELG---------LDRE-------KVNVNGSGvGL---GHPIGCTGARIT 357
Cdd:PRK06064 267 AYKMAGIEPKDIDVAEVHDCFTiAEILAYE-DLGfakkgeggkLAREgqtyiggDIPVNPSG-GLkakGHPVGATGVSQA 344
|
410 420
....*....|....*....|....*...
gi 446474221 358 VSLIHELKRRGlEKGIASLcVGGGIGVA 385
Cdd:PRK06064 345 VEIVWQLRGEA-EKGRQQV-IGAGYGLT 370
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
29-354 |
1.94e-08 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 55.62 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 29 LAVPVLQEAVKRGGVEPHEVDE----VILGHCI--QRTDEANTAR----------------------TAALAAGFPDTVT 80
Cdd:cd00834 74 FALAAAEEALADAGLDPEELDPerigVVIGSGIggLATIEEAYRAllekgprrvspffvpmalpnmaAGQVAIRLGLRGP 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 81 GYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMsSSPYALkqhrWGqrlqhgeirdtvwevledpihHIMMGETA 160
Cdd:cd00834 154 NYTVSTACASGAHAIGDAARLIRLGRADVVIAGGAEAL-ITPLTL----AG---------------------FAALRALS 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 161 enlveqyeiTREEQDEVALRShtlalkaiesghFDdqivpitiKERrkevvfskdehpraditaeklaglkpafrkDGSV 240
Cdd:cd00834 208 ---------TRNDDPEKASRP------------FD--------KDR------------------------------DGFV 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 241 tagnasgLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAG-----VDPKIMGIGPAPAIRKGLEKVDWSLEDADLL--- 312
Cdd:cd00834 229 -------LGEGAGVLVLESLEHAKARGAKIYAEILGYGASSdayhiTAPDPDGEGAARAMRAALADAGLSPEDIDYInah 301
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 446474221 313 ----EINEafAAQYLAVEKELGLDREKVNVNGSGVGLGHPIGCTGA 354
Cdd:cd00834 302 gtstPLND--AAESKAIKRVFGEHAKKVPVSSTKSMTGHLLGAAGA 345
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
88-120 |
1.90e-06 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 49.32 E-value: 1.90e-06
10 20 30
....*....|....*....|....*....|...
gi 446474221 88 CSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSS 120
Cdd:COG0304 161 CASGAHAIGEAYRLIRRGRADVMIAGGAEAAIT 193
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
88-353 |
3.67e-06 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 48.74 E-value: 3.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 88 CSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSssPYALKQHrWGQRLQ----HGEIRDTVWEVLEDPIHHIMMGETAENL 163
Cdd:PRK08256 80 CSTGSTALFLARQAVRSGAADCALALGFEQMQ--PGALGSV-WDDRPSplerFDKALAELQGFDPAPPALRMFGGAGREH 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 164 VEQYEITREeqdevalrshTLAlkaiesghfddqivPITIKERRKEV-----VFskdehpRADITAEKLAGLKPAFrkdG 238
Cdd:PRK08256 157 MEKYGTTAE----------TFA--------------KIGVKARRHAAnnpyaQF------RDEYTLEDVLASPMIW---G 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 239 SVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSV--------AGVDP-KIMGIG-PAPAIRKGLEKVDWSLED 308
Cdd:PRK08256 204 PLTRLQCCPPTCGAAAAIVCSEEFARKHGLDRAVEIVAQAMttdtpstfDGRSMiDLVGYDmTRAAAQQVYEQAGIGPED 283
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446474221 309 ADLLEINEAFAAQYLAVEKELGLDRE----------------KVNVNGSGvGL---GHPIGCTG 353
Cdd:PRK08256 284 IDVVELHDCFSANELLTYEALGLCPEgeaekfiddgdntyggRWVVNPSG-GLlskGHPLGATG 346
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
28-355 |
4.17e-06 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 48.49 E-value: 4.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 28 ELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDT-VTgyTIQRQCSSGMQAIMSAAMQIQLGV 106
Cdd:PRK06157 29 DLMVEAFLEALADAGIEPKDIDAAWFGTHYDEIGSGKSGTPLSRALRLPNIpVT--RVENFCATGSEAFRGAVYAVASGA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 107 SDVVVAGGVEAMSSSPYAlkqhrwGQRLQH-GEIRDTVWEVLEDPihhIMMGETAENLVEQYEITREEQDE----VALRS 181
Cdd:PRK06157 107 YDIALALGVEKLKDTGYG------GLPVANpGTLADMTMPNVTAP---GNFAQLASAYAAKYGVSREDLKRamahVSVKS 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 182 HTLALKAiESGHFddqivpitikerRKEVvfSKDEHPRADITAEKLaGLKpafrkdgsvtagNASGLNDGSAVLVLMSEE 261
Cdd:PRK06157 178 HANGARN-PKAHL------------RKAV--TEEQVLKAPMIAGPL-GLF------------DCCGVSDGAAAAIVTTPE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 262 KAKEKGLQPLARIVGYSVA-GVDPKIMGIG----PAPAIRKGLEK------VDWSLEDADLLEINEAFAAQYLAVEKELG 330
Cdd:PRK06157 230 IARALGKKDPVYVKALQLAvSNGWELQYNGwdgsYFPTTRIAARKayreagITDPREELSMAEVHDCFSITELVTMEDLG 309
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 446474221 331 LDRE----------------KVNVNGSGvGL---GHPIGCTGAR 355
Cdd:PRK06157 310 LSERgqawrdvldgffdadgGLPCQIDG-GLkcfGHPIGASGLR 352
|
|
| PRK07314 |
PRK07314 |
beta-ketoacyl-ACP synthase II; |
248-354 |
1.43e-05 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 235987 [Multi-domain] Cd Length: 411 Bit Score: 46.71 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 248 LNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAG-----VDPKIMGIGPAPAIRKGLEKVDWSLEDADLL-------EIN 315
Cdd:PRK07314 230 MGEGAGILVLEELEHAKARGAKIYAEVVGYGMTGdayhmTAPAPDGEGAARAMKLALKDAGINPEDIDYInahgtstPAG 309
|
90 100 110
....*....|....*....|....*....|....*....
gi 446474221 316 EAFAAQylAVEKELGLDREKVNVNGSGVGLGHPIGCTGA 354
Cdd:PRK07314 310 DKAETQ--AIKRVFGEHAYKVAVSSTKSMTGHLLGAAGA 346
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
19-365 |
2.70e-05 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 46.04 E-value: 2.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 19 GALKNVTPVELAVPVLQEAVKRGGVEPHE--VDEVILGHCIQR--TDEANTARTAALAAGFPDTVTG------YTIQRQC 88
Cdd:PTZ00455 41 GKKENKTLEELLATAIQGTLENTGLDGKAalVDKVVVGNFLGElfSSQGHLGPAAVGSLGQSGASNAllykpaMRVEGAC 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 89 SSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYALKQHRWGQRLQHGEIRdtvweVLEDPIHHIMMGETAENLVEQYE 168
Cdd:PTZ00455 121 ASGGLAVQSAWEALLAGTSDIALVVGVEVQTTVSARVGGDYLARAADYRRQR-----KLDDFTFPCLFAKRMKYIQEHGH 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 169 ITREEQDEVALrshtlalKAIESGHFDdqivPITIKERRKevvFSKDEHPRADITAEKLAG---LKPAFRkdgsvtAGNA 245
Cdd:PTZ00455 196 FTMEDTARVAA-------KAYANGNKN----PLAHMHTRK---LSLEFCTGASDKNPKFLGnetYKPFLR------MTDC 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 246 SGLNDGSAVLVLMSEEKAKEKGLQP----LARIVGYSVAG-------VDPKIMGIGPAPAiRKGLEKVDWSLEDADLLEI 314
Cdd:PTZ00455 256 SQVSDGGAGLVLASEEGLQKMGLSPndsrLVEIKSLACASgnlyedpPDATRMFTSRAAA-QKALSMAGVKPSDLQVAEV 334
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446474221 315 NEAFAAQYLAVEKELG------------------LDREKVNVNGSGVGLGHPIGCTGARITVSLIHELK 365
Cdd:PTZ00455 335 HDCFTIAELLMYEALGiaeyghakdlirngatalEGRIPVNTGGGLLSFGHPVGATGVKQIMEVYRQMK 403
|
|
| PRK06066 |
PRK06066 |
thiolase domain-containing protein; |
78-353 |
5.31e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 180380 [Multi-domain] Cd Length: 385 Bit Score: 45.13 E-value: 5.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 78 TVTGytiqrqcsSGMQAIMSAAMQIQLGVSDVVVaggVEAmssspyalkqhrwgqrlqHGEIRD--TVWEVLE---DPIH 152
Cdd:PRK06066 83 TVAG--------DGLQGLAHAVMHINSGLANVVV---VEA------------------HSKPSDilTFSDVVKfamDPIY 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 153 ---------HIMMGETAENLVEQYEITREEQDEVALRSHTLALKAIESGHfddqIVPITIKE-RRKEVVFskDEHPRADI 222
Cdd:PRK06066 134 vrpigppnpHFIAGLDAVKFMSRKGITREDLALVVEKNKKAGLSNPRASY----ASNISLEDvLSSEYVV--YPLTELDI 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 223 taeklaglkpafrkdgsvtagnaSGLNDGSAVLVLMSEEKAKEKGLQPL-ARIVGYSVAGVDPKIMGIGPAPAIRKG--- 298
Cdd:PRK06066 208 -----------------------APFVDGAIVVVLASEEVAKKLTDDPVwIKGIGWSTESSNLETAELGKANYMRIAadm 264
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446474221 299 ---LEKVDWSLEDADLLEINEAFAAQYLAVEKELGLDRE------------------KVNVNGSGVGLGHPIGCTG 353
Cdd:PRK06066 265 aykMAGIESPRKEVDAAEVDDRYSYKELQHIEALRLSEEpekdsllregnfdpqgelPVNPSGGHLAKGVPLEASG 340
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
231-356 |
7.33e-05 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 44.68 E-value: 7.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 231 KPAFRKDGS---VTAG-----NASGLNDGSAVLVLMSEEKAKE-KGLQPLARIVGY--SVAGV--DPKIMGIGPAP---- 293
Cdd:PRK06289 197 DEATNDDDAtnpVVEGrlrrqDCSQVTDGGAGVVLASDAYLRDyADARPIPRIKGWghRTAPLglEQKLDRSAGDPyvlp 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 294 ----AIRKGLEKVDWSLEDADLLEINEAF-AAQYLAVEkELGLD------------------REKVNVNGSGVGLGHPIG 350
Cdd:PRK06289 277 hvrqAVLDAYRRAGVGLDDLDGFEVHDCFtPSEYLAID-HIGLTgpgeswkaiengeiaiggRLPINPSGGLIGGGHPVG 355
|
....*.
gi 446474221 351 CTGARI 356
Cdd:PRK06289 356 ASGVRM 361
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
29-120 |
3.87e-04 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 41.85 E-value: 3.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 29 LAVPVLQEAVKRGGVEPHEVDE----VILGHCIQRTDEANTAR-TAALAAGFPDTVTG-------------------YTI 84
Cdd:pfam00109 90 LLLEAAWEALEDAGITPDSLDGsrtgVFIGSGIGDYAALLLLDeDGGPRRGSPFAVGTmpsviagrisyflglrgpsVTV 169
|
90 100 110
....*....|....*....|....*....|....*.
gi 446474221 85 QRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSS 120
Cdd:pfam00109 170 DTACSSSLVAIHAAVQSIRSGEADVALAGGVNLLLT 205
|
|
| PRK09185 |
PRK09185 |
beta-ketoacyl-ACP synthase; |
82-115 |
1.30e-03 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 236398 [Multi-domain] Cd Length: 392 Bit Score: 40.60 E-value: 1.30e-03
10 20 30
....*....|....*....|....*....|....
gi 446474221 82 YTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGV 115
Cdd:PRK09185 154 YTISTACSSSAKVFASARRLLEAGLCDAAIVGGV 187
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
1-353 |
2.22e-03 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 39.93 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 1 MHNVVITAAVRSPIGTFGGAlknvTPVELAVPVLQEAVKRGGVEPHEVDEVILGHC---IQRTDeantaRTAALAAGFPD 77
Cdd:PRK07516 1 MMTASIVGWAHTPFGKLDAE----TLESLIVRVAREALAHAGIAAGDVDGIFLGHFnagFSPQD-----FPASLVLQADP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 78 T---VTGYTIQRQCSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSSSPYA------LKQhrwGQRLQHGEIRDTVWEVLe 148
Cdd:PRK07516 72 AlrfKPATRVENACATGSAAVYAALDAIEAGRARIVLVVGAEKMTATPTAevgdilLGA---SYLKEEGDTPGGFAGVF- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 149 dpihhimmGETAENLVEQYeitreeQDevalRSHTLALKAIESgHFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLA 228
Cdd:PRK07516 148 --------GRIAQAYFQRY------GD----QSDALAMIAAKN-HANGVANPYAQMRKDLGFEFCRTVSEKNPLVAGPLR 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 229 glkpafRKDGSVtagnasgLNDGSAVLVLMSEEKAKEkglqpLARIVGY-SVAGV---------DPKIMGiGPAPAIRKG 298
Cdd:PRK07516 209 ------RTDCSL-------VSDGAAALVLADAETARA-----LQRAVRFrARAHVndflplsrrDPLAFE-GPRRAWQRA 269
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446474221 299 LEKVDWSLEDADLLEINEAFAAQYLAVEKELGLDRE----------------KVNVNGSGvGL---GHPIGCTG 353
Cdd:PRK07516 270 LAQAGVTLDDLSFVETHDCFTIAELIEYEAMGLAPPgqgarairegwtakdgKLPVNPSG-GLkakGHPIGATG 342
|
|
| PRK07910 |
PRK07910 |
beta-ketoacyl-ACP synthase; |
88-354 |
2.72e-03 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 236129 [Multi-domain] Cd Length: 418 Bit Score: 39.71 E-value: 2.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 88 CSSGMQAIMSAAMQIQLGVSDVVVAGGVEAmssspyalkqhrwgqrlqhgeirdtvwevledpihhimmgetaenlveqy 167
Cdd:PRK07910 171 CASGSEAIAQAWRQIVLGEADIAICGGVET-------------------------------------------------- 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 168 eitreeqdevalrshtlalkAIESghfddqiVPITIKERRKEVVFSKDEHPraditaeklAGLKPAFRKD--GSVtagna 245
Cdd:PRK07910 201 --------------------RIEA-------VPIAGFAQMRIVMSTNNDDP---------AGACRPFDKDrdGFV----- 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 246 sgLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAG-----VDPKIMGIGPAPAIRKGLEKVdwSLEDADLLEINeAFA- 319
Cdd:PRK07910 240 --FGEGGALMVIETEEHAKARGANILARIMGASITSdgfhmVAPDPNGERAGHAMTRAIELA--GLTPGDIDHVN-AHAt 314
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 446474221 320 -------AQYLAVEKELGLDREKVNVNGSgvGLGHPIGCTGA 354
Cdd:PRK07910 315 gtsvgdvAEGKAINNALGGHRPAVYAPKS--ALGHSVGAVGA 354
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
14-115 |
3.45e-03 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 38.95 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 14 IGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTARTAALAAGFPDtVTGYTIQRQCSSGMQ 93
Cdd:cd00827 36 IGQRHMAGDDEDVPTMAVEAARRALERAGIDPDDIGLLIVATESPIDKGKSAATYLAELLGLTN-AEAFDLKQACYGGTA 114
|
90 100
....*....|....*....|....
gi 446474221 94 AIMSAAMQIQLGVSD--VVVAGGV 115
Cdd:cd00827 115 ALQLAANLVESGPWRyaLVVASDI 138
|
|
| PRK07937 |
PRK07937 |
lipid-transfer protein; Provisional |
150-356 |
6.70e-03 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181173 [Multi-domain] Cd Length: 352 Bit Score: 38.13 E-value: 6.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 150 PIHHIMMGETAENLVEQYEITREEQDEVALRSHTLALKaiesghfddqivpitikERRKEVVFSKDEHPRADITAEKLag 229
Cdd:PRK07937 136 PDSVSMAGLQARAGLDAGKWTEEQMAEVAARSRADARR-----------------NPSAEPSISVDELLARPYFADPL-- 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 230 lkpafrkdgsvTAGNASGLNDGSAVLVLMSEEKAKEKGLQPlARIVGYSvAGVDPKIMG---IGPAPAIRKGLEKVDWSL 306
Cdd:PRK07937 197 -----------RRHDIAPITDGAAAVVLAAGDRARELRERP-AWITGIE-HRIESPSLGardLTRSPSTALAAEAATGGD 263
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446474221 307 EDA-DLLEINEAFAAQYLAVEKELGLDrEKVNVNGSGVGL-GHPIGCTG-ARI 356
Cdd:PRK07937 264 AGGvDVAELHAPFTHQELILREALGLG-DKTKVNPSGGALaANPMFAAGlERI 315
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
20-120 |
7.02e-03 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 38.17 E-value: 7.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446474221 20 ALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTDEANTArtAALAA--GFPDTVtGYTIQRQCSSGMQAIMS 97
Cdd:COG0332 45 AAPDETTSDLAVEAARKALEAAGIDPEDIDLIIVATVTPDYLFPSTA--CLVQHklGAKNAA-AFDINAACSGFVYALSV 121
|
90 100
....*....|....*....|....
gi 446474221 98 AAMQIQLGVSD-VVVAGGvEAMSS 120
Cdd:COG0332 122 AAALIRSGQAKnVLVVGA-ETLSR 144
|
|
| PRK06816 |
PRK06816 |
StlD/DarB family beta-ketosynthase; |
88-139 |
7.96e-03 |
|
StlD/DarB family beta-ketosynthase;
Pssm-ID: 235866 Cd Length: 378 Bit Score: 37.97 E-value: 7.96e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 446474221 88 CSSGMQAIMSAAMQIQLGVSDVVVAGGVEAMSS----SPYALKQHRWGQRLQHGEI 139
Cdd:PRK06816 124 CAAGMMALKYAYLSVKAGESRNAVATASELASRwfraSRFEAEEEKLAELEENPEI 179
|
|
| |
