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Conserved domains on  [gi|446837844|ref|WP_000915100|]
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DUF4352 domain-containing protein [Bacillus toyonensis]

Protein Classification

DUF4352 domain-containing protein( domain architecture ID 37154)

DUF4352 domain-containing protein similar to Bacillus subtilis lipoprotein YjhA

CATH:  2.60.40.1240
SCOP:  4005270

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4352 super family cl13117
Domain of unknown function (DUF4352); Members of these family are putative lipoproteins that ...
 40-135 1.08e-07

Domain of unknown function (DUF4352); Members of these family are putative lipoproteins that fall into the Antigen MPT63/MPB63 (immunoprotective extracellular protein) superfamily.


The actual alignment was detected with superfamily member pfam11611:

Pssm-ID: 448816  Cd Length: 125  Bit Score: 48.11  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446837844   40 YKIGETVDVDGLQVTLDSV----QLGYPDYTIDKKKDDILGIVFTVKNNSKKEIPFAFYEFEITNKKGTKFK-----EYK 110
Cdd:pfam11611   1 YKVGETVKVGDLEVTVNSVeytlSVGSNEYLQPDAGNEFLIVDVTVENIGDEALTVNSSQFKLYDGDGKEYDadfsaSSK 80

                          90       100
                  ....*....|....*....|....*
gi 446837844  111 YDSFISKKVAPDEKIQDIMRFDVDK 135
Cdd:pfam11611  81 ADILFLGTLNPGKTVSGSLVFDVPK 105
 
Name Accession Description Interval E-value
DUF4352 pfam11611
Domain of unknown function (DUF4352); Members of these family are putative lipoproteins that ...
 40-135 1.08e-07

Domain of unknown function (DUF4352); Members of these family are putative lipoproteins that fall into the Antigen MPT63/MPB63 (immunoprotective extracellular protein) superfamily.


Pssm-ID: 431958  Cd Length: 125  Bit Score: 48.11  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446837844   40 YKIGETVDVDGLQVTLDSV----QLGYPDYTIDKKKDDILGIVFTVKNNSKKEIPFAFYEFEITNKKGTKFK-----EYK 110
Cdd:pfam11611   1 YKVGETVKVGDLEVTVNSVeytlSVGSNEYLQPDAGNEFLIVDVTVENIGDEALTVNSSQFKLYDGDGKEYDadfsaSSK 80

                          90       100
                  ....*....|....*....|....*
gi 446837844  111 YDSFISKKVAPDEKIQDIMRFDVDK 135
Cdd:pfam11611  81 ADILFLGTLNPGKTVSGSLVFDVPK 105
 
Name Accession Description Interval E-value
DUF4352 pfam11611
Domain of unknown function (DUF4352); Members of these family are putative lipoproteins that ...
 40-135 1.08e-07

Domain of unknown function (DUF4352); Members of these family are putative lipoproteins that fall into the Antigen MPT63/MPB63 (immunoprotective extracellular protein) superfamily.


Pssm-ID: 431958  Cd Length: 125  Bit Score: 48.11  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446837844   40 YKIGETVDVDGLQVTLDSV----QLGYPDYTIDKKKDDILGIVFTVKNNSKKEIPFAFYEFEITNKKGTKFK-----EYK 110
Cdd:pfam11611   1 YKVGETVKVGDLEVTVNSVeytlSVGSNEYLQPDAGNEFLIVDVTVENIGDEALTVNSSQFKLYDGDGKEYDadfsaSSK 80

                          90       100
                  ....*....|....*....|....*
gi 446837844  111 YDSFISKKVAPDEKIQDIMRFDVDK 135
Cdd:pfam11611  81 ADILFLGTLNPGKTVSGSLVFDVPK 105
BsuPI pfam12690
Intracellular proteinase inhibitor; This is a bacterial domain which has been named BsuPI in ...
 70-125 2.81e-03

Intracellular proteinase inhibitor; This is a bacterial domain which has been named BsuPI in Bacillus subtilis. This domain is found in Swiss:P39804, where it has been suggested to regulate the major intracellular proteinase (ISP-1) activity in vivo. The structure of proteins in this family adopt an Ig-like fold.


Pssm-ID: 432721  Cd Length: 100  Bit Score: 35.28  E-value: 2.81e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446837844   70 KKDDILGIVFTVKNNSKKEIPFAF-----YEFEITNKKGTKFKEYKYD-----SFISKKVAPDEKI 125
Cdd:pfam12690   9 QSGEGVEFTLTVTNPSDEAVTLTFssgqkYDLVVRDEEGEEVWRYSDGrmftqALQSETLAPGESL 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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