|
Name |
Accession |
Description |
Interval |
E-value |
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-194 |
1.26e-43 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 145.72 E-value: 1.26e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIR-----QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG----YC 71
Cdd:COG1124 1 MLEVRNLSVSygqggRRVPVL-KDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRrkafRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 PVQLVPQHPELTFNP----WRSIADSLQDFWSPD-----AEMMARLHIAPEWLTRRPGQLSGGElarlallraldpRTR- 141
Cdd:COG1124 80 RVQMVFQDPYASLHPrhtvDRILAEPLRIHGLPDreeriAELLEQVGLPPSFLDRYPHQLSGGQ------------RQRv 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446870191 142 -----------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG1124 148 aiaralilepeLLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAV 211
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-194 |
2.32e-40 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 136.48 E-value: 2.32e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDL----LIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP---- 72
Cdd:cd03257 1 LLEVKNLsvsfPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLrkir 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 ---VQLVPQHPELTFNPWRSIADSL-------QDFWSPDA------EMMARLHIAPEWLTRRPGQLSGGElarlallral 136
Cdd:cd03257 81 rkeIQMVFQDPMSSLNPRMTIGEQIaeplrihGKLSKKEArkeavlLLLVGVGLPEEVLNRYPHELSGGQ---------- 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 137 dpRTR------------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03257 151 --RQRvaiaralalnpkLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAV 218
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-194 |
5.07e-39 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 139.65 E-value: 5.07e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDL-----LIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP--- 72
Cdd:COG1123 260 LLEVRNLskrypVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSlre 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 ----VQLVPQHPELTFNPWRSIADSL------QDFWSPD------AEMMARLHIAPEWLTRRPGQLSGGElarlallral 136
Cdd:COG1123 340 lrrrVQMVFQDPYSSLNPRMTVGDIIaeplrlHGLLSRAerrervAELLERVGLPPDLADRYPHELSGGQ---------- 409
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 137 dpRTR------------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG1123 410 --RQRvaiaralalepkLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAV 477
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-194 |
1.47e-32 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 121.93 E-value: 1.47e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIR--QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKP---LSGEVLVDGKPLANCGY----C 71
Cdd:COG1123 4 LLEVRDLSVRypGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHggrISGEVLLDGRDLLELSEalrgR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 PVQLVPQHPELTFNPWR---SIADSLQDFWSPDAEMMAR-------LHIApEWLTRRPGQLSGGELARLALLRALDPRTR 141
Cdd:COG1123 84 RIGMVFQDPMTQLNPVTvgdQIAEALENLGLSRAEARARvlelleaVGLE-RRLDRYPHQLSGGQRQRVAIAMALALDPD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446870191 142 FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG1123 163 LLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVV 215
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
2-194 |
7.73e-32 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 114.14 E-value: 7.73e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCP------VQL 75
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSA--MPPpewrrqVAY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 VPQHPELtfnpWR-SIADSLQDFWS-----PDAE----MMARLHIAPEWLTRRPGQLSGGElarlallraldpRTR---- 141
Cdd:COG4619 79 VPQEPAL----WGgTVRDNLPFPFQlrerkFDREraleLLERLGLPPDILDKPVERLSGGE------------RQRlali 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 142 --------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG4619 143 ralllqpdVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLT 203
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
10-194 |
3.35e-29 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 107.55 E-value: 3.35e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG----YCPVQLVPQHPELTF- 84
Cdd:cd03225 11 DGARPAL-DDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSlkelRRKVGLVFQNPDDQFf 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 --NPWRSIADSLQDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGELArlallraldpR----------TRFLIAD 146
Cdd:cd03225 90 gpTVEEEVAFGLENLGLPEEEIEERVEEAlelvglEGLRDRSPFTLSGGQKQ----------RvaiagvlamdPDILLLD 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446870191 147 EITAQLDPATQRDVWTFLLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03225 160 EPTAGLDPAGRRELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIV 206
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-194 |
2.54e-27 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 102.80 E-value: 2.54e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDL-LIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGY----CPVQLV 76
Cdd:COG1122 1 IELENLsFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLrelrRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 77 PQHPE--LtFNP--WRSIADSLQDFWSPDAEM-------MARLHIApEWLTRRPGQLSGGElarlallraldpRTR---- 141
Cdd:COG1122 81 FQNPDdqL-FAPtvEEDVAFGPENLGLPREEIrerveeaLELVGLE-HLADRPPHELSGGQ------------KQRvaia 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 142 --------FLIADEITAQLDPATQRDVWTFLLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG1122 147 gvlamepeVLVLDEPTAGLDPRGRRELLELLKRL-NKEGKTVIIVTHDLDLVAELADRVIV 206
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
11-188 |
1.35e-25 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 102.99 E-value: 1.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA---------NCGYcpvqlVPQHPE 81
Cdd:COG2274 486 DSPPVL-DNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRqidpaslrrQIGV-----VLQDVF 559
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 82 LtFNpwRSIADSLQdFWSPDAEM--------MARLHiapEWLTRRP-----------GQLSGGElarlallraldpRTRF 142
Cdd:COG2274 560 L-FS--GTIRENIT-LGDPDATDeeiieaarLAGLH---DFIEALPmgydtvvgeggSNLSGGQ------------RQRL 620
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 143 LIA------------DEITAQLDPATQRDVWTFLLELCQRRALgmVVISHQKALVAQV 188
Cdd:COG2274 621 AIArallrnprililDEATSALDAETEAIILENLRRLLKGRTV--IIIAHRLSTIRLA 676
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-187 |
2.75e-25 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 101.76 E-value: 2.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIR--QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCPVQL---- 75
Cdd:COG4988 337 IELEDVSFSypGGRPAL-DGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSD--LDPASWrrqi 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 --VPQHPELtFNPwrSIADSLqDFWSPDA---EMMARLHIA--PEWLTRRPG-----------QLSGGElarlallrald 137
Cdd:COG4988 414 awVPQNPYL-FAG--TIRENL-RLGRPDAsdeELEAALEAAglDEFVAALPDgldtplgeggrGLSGGQ----------- 478
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446870191 138 pRTR------------FLIADEITAQLDPATQRDVWTFLLELCQRRALgmVVISHQKALVAQ 187
Cdd:COG4988 479 -AQRlalarallrdapLLLLDEPTAHLDAETEAEILQALRRLAKGRTV--ILITHRLALLAQ 537
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
11-188 |
2.94e-24 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 93.60 E-value: 2.94e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA---------NCGYcpvqlVPQHPE 81
Cdd:cd03228 13 RPKPVL-KDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRdldleslrkNIAY-----VPQDPF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 82 LtFNpwRSIADSLqdfwspdaemmarlhiapewltrrpgqLSGGElarlallraldpRTR------------FLIADEIT 149
Cdd:cd03228 87 L-FS--GTIRENI---------------------------LSGGQ------------RQRiaiarallrdppILILDEAT 124
|
170 180 190
....*....|....*....|....*....|....*....
gi 446870191 150 AQLDPATQRDVWTFLLELCQRRAlgMVVISHQKALVAQV 188
Cdd:cd03228 125 SALDPETEALILEALRALAKGKT--VIVIAHRLSTIRDA 161
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
19-194 |
1.47e-23 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 95.12 E-value: 1.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPL---SGEVLVDGKPLANCGycP----------VQLVPQHPELTFN 85
Cdd:COG0444 23 GVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPgitSGEILFDGEDLLKLS--EkelrkirgreIQMIFQDPMTSLN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 86 P----WRSIADSLQ--DFWSPDA------EMMARLHI--APEWLTRRPGQLSGGElarlallraldpRTR---------- 141
Cdd:COG0444 101 PvmtvGDQIAEPLRihGGLSKAEareraiELLERVGLpdPERRLDRYPHELSGGM------------RQRvmiaralale 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 142 --FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG0444 169 pkLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAV 223
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-180 |
4.38e-23 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 91.64 E-value: 4.38e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDL--LIRQGE---KVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--------- 66
Cdd:COG1136 4 LLELRNLtkSYGTGEgevTAL-RGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISslserelar 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 67 ----NCGYcpvqlVPQH----PELT--FN---PWR----SIADSLQDFwspdAEMMARLHIApEWLTRRPGQLSGGElar 129
Cdd:COG1136 83 lrrrHIGF-----VFQFfnllPELTalENvalPLLlagvSRKERRERA----RELLERVGLG-DRLDHRPSQLSGGQ--- 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446870191 130 lallraldpRTR------------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:COG1136 150 ---------QQRvaiaralvnrpkLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTH 203
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
2-188 |
4.72e-23 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 95.60 E-value: 4.72e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIR---QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCPVQL--- 75
Cdd:COG4987 334 LELEDVSFRypgAGRPVL-DGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRD--LDEDDLrrr 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 ---VPQHPELtFNpwRSIADSLQdFWSPDA---EMMARLHIA--PEWLTRRPG-----------QLSGGElarlallral 136
Cdd:COG4987 411 iavVPQRPHL-FD--TTLRENLR-LARPDAtdeELWAALERVglGDWLAALPDgldtwlgeggrRLSGGE---------- 476
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446870191 137 dpRTRFLIA------------DEITAQLDPATQRDVWTFLLELCQRRALgmVVISHQKALVAQV 188
Cdd:COG4987 477 --RRRLALArallrdapilllDEPTEGLDAATEQALLADLLEALAGRTV--LLITHRLAGLERM 536
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-181 |
5.32e-23 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 91.00 E-value: 5.32e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--------ANCGYCP 72
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIrdaredyrRRLAYLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 vQLVPQHPELT------FnpWRSIADSLQDFWSPDaEMMARLHIAPEwLTRRPGQLSGGElarlallraldpRTRFLIA- 145
Cdd:COG4133 82 -HADGLKPELTvrenlrF--WAALYGLRADREAID-EALEAVGLAGL-ADLPVRQLSAGQ------------KRRVALAr 144
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446870191 146 -----------DEITAQLDPATQRDVWTFLLELCQRRalGMVVI-SHQ 181
Cdd:COG4133 145 lllspaplwllDEPFTALDAAGVALLAELIAAHLARG--GAVLLtTHQ 190
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-194 |
1.13e-22 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 91.30 E-value: 1.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANC----GYcpvqlV 76
Cdd:COG1121 6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRArrriGY-----V 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 77 PQH--------------------PELTFNPWRSIADslqdfWSPDAEMMARLHIApEWLTRRPGQLSGGElarlallral 136
Cdd:COG1121 81 PQRaevdwdfpitvrdvvlmgryGRRGLFRRPSRAD-----REAVDEALERVGLE-DLADRPIGELSGGQ---------- 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 137 dpRTRFLIA------------DEITAQLDPATQRDVWTFLLELCQRRaLGMVVISHQKALVAQVCSSLLV 194
Cdd:COG1121 145 --QQRVLLAralaqdpdllllDEPFAGVDAATEEALYELLRELRREG-KTILVVTHDLGAVREYFDRVLL 211
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-194 |
2.64e-22 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 88.65 E-value: 2.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 3 SCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCPVQL------V 76
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLAS--LSPKELarkiayV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 77 PQhpeltfnpwrsiadslqdfwspdaeMMARLHIAPewLTRRP-GQLSGGElarlallraldpRTRFLIA---------- 145
Cdd:cd03214 79 PQ-------------------------ALELLGLAH--LADRPfNELSGGE------------RQRVLLAralaqeppil 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446870191 146 --DEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03214 120 llDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVIL 170
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
19-194 |
2.76e-22 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 90.12 E-value: 2.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--------NCGYcpvqlVPQHPelTFNPWRSI 90
Cdd:COG1131 18 GVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVArdpaevrrRIGY-----VPQEP--ALYPDLTV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 ADSLqDFWS-----PDA-------EMMARLHIApEWLTRRPGQLSGGElarlallraldpRTRFLIA------------D 146
Cdd:COG1131 91 RENL-RFFArlyglPRKeareridELLELFGLT-DAADRKVGTLSGGM------------KQRLGLAlallhdpellilD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446870191 147 EITAQLDPATQRDVWTFLLELCQRralGMVVI--SHQKALVAQVCSSLLV 194
Cdd:COG1131 157 EPTSGLDPEARRELWELLRELAAE---GKTVLlsTHYLEEAERLCDRVAI 203
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
14-180 |
3.03e-22 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 89.45 E-value: 3.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 14 KVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGyCPVQLVPQHPELtFnPWRSIAD- 92
Cdd:cd03293 18 TAL-EDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPG-PDRGYVFQQDAL-L-PWLTVLDn 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 ---SLQDFWSPDAEmmaRLHIAPEWL---------TRRPGQLSGGElarlallraldpRTRFLIA------------DEI 148
Cdd:cd03293 94 valGLELQGVPKAE---ARERAEELLelvglsgfeNAYPHQLSGGM------------RQRVALAralavdpdvlllDEP 158
|
170 180 190
....*....|....*....|....*....|..
gi 446870191 149 TAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:cd03293 159 FSALDALTREQLQEELLDIWRETGKTVLLVTH 190
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
18-180 |
5.30e-22 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 88.70 E-value: 5.30e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANC-------------GYcpvqlVPQH----P 80
Cdd:cd03255 21 KGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLsekelaafrrrhiGF-----VFQSfnllP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 ELTF------------NPWRSIADSLqdfwspdAEMMARLHIApEWLTRRPGQLSGGElarlallraldpRTR------- 141
Cdd:cd03255 96 DLTAlenvelplllagVPKKERRERA-------EELLERVGLG-DRLNHYPSELSGGQ------------QQRvaiaral 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446870191 142 -----FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:cd03255 156 andpkIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTH 199
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-194 |
5.73e-22 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 89.45 E-value: 5.73e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAncGYCPVQL----- 75
Cdd:PRK13548 2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLA--DWSPAELarrra 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 -VPQHPELTF------------NPWRSIADSLQDFWspdAEMMAR---LHIApewlTRRPGQLSGGELA------RLALL 133
Cdd:PRK13548 80 vLPQHSSLSFpftveevvamgrAPHGLSRAEDDALV---AAALAQvdlAHLA----GRDYPQLSGGEQQrvqlarVLAQL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 134 RALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13548 153 WEPDGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVL 213
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-181 |
1.05e-21 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 88.58 E-value: 1.05e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDL-LIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----- 74
Cdd:COG3638 2 MLELRNLsKRYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRrlrrr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 75 --LVPQHPEL----------------TFNPWRSIadsLQDFWSPD----AEMMARLHIApEWLTRRPGQLSGGElarlal 132
Cdd:COG3638 82 igMIFQQFNLvprlsvltnvlagrlgRTSTWRSL---LGLFPPEDreraLEALERVGLA-DKAYQRADQLSGGQ------ 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 133 lraldpRTR------------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQ 181
Cdd:COG3638 152 ------QQRvaiaralvqepkLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQ 206
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
18-194 |
1.46e-21 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 88.02 E-value: 1.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKP---LANCGYCPVQ----LVPQHpeltFNPWRS- 89
Cdd:cd03258 22 KDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDltlLSGKELRKARrrigMIFQH----FNLLSSr 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 -----IADSLQDFWSPDAEMMARlhiAPEWLT---------RRPGQLSGGELARL--ALLRALDPRtrFLIADEITAQLD 153
Cdd:cd03258 98 tvfenVALPLEIAGVPKAEIEER---VLELLElvgledkadAYPAQLSGGQKQRVgiARALANNPK--VLLCDEATSALD 172
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446870191 154 PATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03258 173 PETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAV 213
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-194 |
2.03e-21 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 85.76 E-value: 2.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 3 SCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgycpvqlvpqhpel 82
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAK--------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 tfnpwrsiadslqdfwspdaemmarlhIAPEWLTRRPG---QLSGGELARLA--LLRALDPrtRFLIADEITAQLDPATQ 157
Cdd:cd00267 66 ---------------------------LPLEELRRRIGyvpQLSGGQRQRVAlaRALLLNP--DLLLLDEPTSGLDPASR 116
|
170 180 190
....*....|....*....|....*....|....*..
gi 446870191 158 RDVWTFLLELCQRRALgMVVISHQKALVAQVCSSLLV 194
Cdd:cd00267 117 ERLLELLRELAEEGRT-VIIVTHDPELAELAADRVIV 152
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
7-194 |
3.70e-21 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 87.82 E-value: 3.70e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 7 LLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC-------PVQLVPQH 79
Cdd:PRK10419 18 LSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAqrkafrrDIQMVFQD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 80 PELTFNPWRS----IADSLQDFWSPD--------AEMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADE 147
Cdd:PRK10419 98 SISAVNPRKTvreiIREPLRHLLSLDkaerlaraSEMLRAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDE 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446870191 148 ITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK10419 178 AVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMV 224
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
6-180 |
9.45e-21 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 85.28 E-value: 9.45e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 6 DLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANC----GYcpvqlVPQHPE 81
Cdd:cd03235 4 DLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKErkriGY-----VPQRRS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 82 LTFN-------------------------PWRSIADSLqdfwspdAEMMARLHIApewlTRRPGQLSGGElarlallral 136
Cdd:cd03235 79 IDRDfpisvrdvvlmglyghkglfrrlskADKAKVDEA-------LERVGLSELA----DRQIGELSGGQ---------- 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446870191 137 dpRTRFLIA------------DEITAQLDPATQRDVWTFLLELCQRRaLGMVVISH 180
Cdd:cd03235 138 --QQRVLLAralvqdpdllllDEPFAGVDPKTQEDIYELLRELRREG-MTILVVTH 190
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
5-180 |
2.36e-20 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 84.49 E-value: 2.36e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 5 RDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgyCPVQ-----LVPQH 79
Cdd:cd03259 4 KGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG---VPPErrnigMVFQD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 80 PELtFnPWRSIADS----LQDFWSPDA-------EMMARLHIAPEwLTRRPGQLSGGELARLALLRALDPRTRFLIADEI 148
Cdd:cd03259 81 YAL-F-PHLTVAENiafgLKLRGVPKAeirarvrELLELVGLEGL-LNRYPHELSGGQQQRVALARALAREPSLLLLDEP 157
|
170 180 190
....*....|....*....|....*....|..
gi 446870191 149 TAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:cd03259 158 LSALDAKLREELREELKELQRELGITTIYVTH 189
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
5-194 |
2.37e-20 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 83.39 E-value: 2.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 5 RDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC------PVQLVPQ 78
Cdd:cd03229 4 KNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDElpplrrRIGMVFQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 79 HPELtfNPWRSIADSLqdfwspdaeMMArlhiapewltrrpgqLSGGELARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:cd03229 84 DFAL--FPHLTVLENI---------ALG---------------LSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRR 137
|
170 180 190
....*....|....*....|....*....|....*.
gi 446870191 159 DVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03229 138 EVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVV 173
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1-182 |
7.06e-20 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 83.00 E-value: 7.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPlancgycpvQLVPQHP 80
Cdd:PRK13539 2 MLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGD---------IDDPDVA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 ELT--------FNPWRSIADSLQdFW--------SPDAEMMARLHIAPewLTRRP-GQLSGGElarlallraldpRTRFL 143
Cdd:PRK13539 73 EAChylghrnaMKPALTVAENLE-FWaaflggeeLDIAAALEAVGLAP--LAHLPfGYLSAGQ------------KRRVA 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446870191 144 IA------------DEITAQLDPATQRdvwtFLLELCQRRAL--GMVVIS-HQK 182
Cdd:PRK13539 138 LArllvsnrpiwilDEPTAALDAAAVA----LFAELIRAHLAqgGIVIAAtHIP 187
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-180 |
7.14e-20 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 83.99 E-value: 7.14e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDL----LIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL----ANCGYcp 72
Cdd:COG1116 7 ALELRGVskrfPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVtgpgPDRGV-- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 vqlVPQHPELtFnPWRSIAD----SLQDFWSPDAEMMARlhiAPEWL---------TRRPGQLSGGElarlallraldpR 139
Cdd:COG1116 85 ---VFQEPAL-L-PWLTVLDnvalGLELRGVPKAERRER---ARELLelvglagfeDAYPHQLSGGM------------R 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446870191 140 TR------------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:COG1116 145 QRvaiaralandpeVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTH 197
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
19-194 |
9.38e-20 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 81.68 E-value: 9.38e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--------NCGYcpvqlVPQHPelTFNPWRSI 90
Cdd:cd03230 18 DISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKkepeevkrRIGY-----LPEEP--SLYENLTV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 ADSLqdfwspdaemmarlhiapewltrrpgQLSGGElarlallraldpRTRFLIA------------DEITAQLDPATQR 158
Cdd:cd03230 91 RENL--------------------------KLSGGM------------KQRLALAqallhdpellilDEPTSGLDPESRR 132
|
170 180 190
....*....|....*....|....*....|....*...
gi 446870191 159 DVWTFLLELCQRralGMVVI--SHQKALVAQVCSSLLV 194
Cdd:cd03230 133 EFWELLRELKKE---GKTILlsSHILEEAERLCDRVAI 167
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
18-194 |
2.58e-19 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 84.74 E-value: 2.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQkPLSGEVLVDGKPLAncGYCP---------VQLVPQHPELTFNPWR 88
Cdd:COG4172 303 DGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLD--GLSRralrplrrrMQVVFQDPFGSLSPRM 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 89 SIAD-------SLQDFWSPD------AEMMARLHIAPEWLTRRPGQLSGGElarlallraldpRTR------------FL 143
Cdd:COG4172 380 TVGQiiaeglrVHGPGLSAAerrarvAEALEEVGLDPAARHRYPHEFSGGQ------------RQRiaiaralilepkLL 447
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446870191 144 IADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG4172 448 VLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMV 498
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
12-180 |
7.01e-19 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 83.68 E-value: 7.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCPVQL------VPQHPELtFN 85
Cdd:COG1132 352 DRPVL-KDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRD--LTLESLrrqigvVPQDTFL-FS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 86 pwRSIADSLQdFWSPDAEM--------MARLHiapEWLTRRPG-----------QLSGGElarlallraldpRTR----- 141
Cdd:COG1132 428 --GTIRENIR-YGRPDATDeeveeaakAAQAH---EFIEALPDgydtvvgergvNLSGGQ------------RQRiaiar 489
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446870191 142 -------FLIADEITAQLDPATQRDVWTFLLELCQRRAlgMVVISH 180
Cdd:COG1132 490 allkdppILILDEATSALDTETEALIQEALERLMKGRT--TIVIAH 533
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
18-186 |
1.74e-18 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 82.33 E-value: 1.74e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG----YCPVQLVPQHPELTFNpwrSIADS 93
Cdd:TIGR02857 339 RPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADadswRDQIAWVPQHPFLFAG---TIAEN 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 94 LQdFWSPDA--EMMAR----------LHIAPEWLTRRPGQ----LSGGELARLALLRALDPRTRFLIADEITAQLDPATQ 157
Cdd:TIGR02857 416 IR-LARPDAsdAEIREaleragldefVAALPQGLDTPIGEggagLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETE 494
|
170 180
....*....|....*....|....*....
gi 446870191 158 RDVWTFLLELCQRRALgmVVISHQKALVA 186
Cdd:TIGR02857 495 AEVLEALRALAQGRTV--LLVTHRLALAA 521
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
11-186 |
2.79e-18 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 79.74 E-value: 2.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLWQNLSFSLRPGERLGLSTPSGSGKT-----TLGRVLAGWQKpLSGEVLVDGKPLANCGY--CPVQLVPQHPELT 83
Cdd:PRK10418 13 QAAQPLVHGVSLTLQRGRVLALVGGSGSGKSltcaaALGILPAGVRQ-TAGRVLLDGKPVAPCALrgRKIATIMQNPRSA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 FNPWRSIADSLQDFW------SPDAEMMARLHI-----APEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQL 152
Cdd:PRK10418 92 FNPLHTMHTHARETClalgkpADDATLTAALEAvglenAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDL 171
|
170 180 190
....*....|....*....|....*....|....
gi 446870191 153 DPATQRDVWTFLLELCQRRALGMVVISHQKALVA 186
Cdd:PRK10418 172 DVVAQARILDLLESIVQKRALGMLLVTHDMGVVA 205
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-187 |
3.21e-18 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 78.94 E-value: 3.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQ--GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgycpvqL--- 75
Cdd:COG2884 1 MIRFENVSKRYpgGREAL-SDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSR-------Lkrr 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 -VPQHPeltfnpwRSIADSLQDFW-------------------SPDAEMMARlhiAPEWLT---------RRPGQLSGGE 126
Cdd:COG2884 73 eIPYLR-------RRIGVVFQDFRllpdrtvyenvalplrvtgKSRKEIRRR---VREVLDlvglsdkakALPHELSGGE 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 127 larlallraldpRTR------------FLIADEITAQLDPATQRDVWTFLLELCQRralGMVVI--SHQKALVAQ 187
Cdd:COG2884 143 ------------QQRvaiaralvnrpeLLLADEPTGNLDPETSWEIMELLEEINRR---GTTVLiaTHDLELVDR 202
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
10-193 |
4.97e-18 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 78.09 E-value: 4.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQLVPQhpELTFNPWRS 89
Cdd:cd03269 9 RFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNRIGYLPE--ERGLYPKMK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 IADSLQDFWS------PDA-----EMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:cd03269 87 VIDQLVYLAQlkglkkEEArrridEWLERLELS-EYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVE 165
|
170 180 190
....*....|....*....|....*....|....*..
gi 446870191 159 DVWTFLLELcqrRALGMVVI--SHQKALVAQVCSSLL 193
Cdd:cd03269 166 LLKDVIREL---ARAGKTVIlsTHQMELVEELCDRVL 199
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
2-188 |
6.39e-18 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 76.87 E-value: 6.39e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIR--QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL---------ANCGY 70
Cdd:cd03246 1 LEVENVSFRypGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADIsqwdpnelgDHVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 71 cpvqlVPQHPELtFNPwrSIADSLqdfwspdaemmarlhiapewltrrpgqLSGGELARLALLRALDPRTRFLIADEITA 150
Cdd:cd03246 81 -----LPQDDEL-FSG--SIAENI---------------------------LSGGQRQRLGLARALYGNPRILVLDEPNS 125
|
170 180 190
....*....|....*....|....*....|....*...
gi 446870191 151 QLDPATQRDVWTFLLELcQRRALGMVVISHQKALVAQV 188
Cdd:cd03246 126 HLDVEGERALNQAIAAL-KAAGATRIVIAHRPETLASA 162
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
5-194 |
1.20e-17 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 80.13 E-value: 1.20e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 5 RDLLIR-QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLG----RVLAGwqkplSGEVLVDGKPLANCG---YCPV--- 73
Cdd:PRK15134 289 KGILKRtVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGlallRLINS-----QGEIWFDGQPLHNLNrrqLLPVrhr 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 74 -QLVPQHPELTFNPWRS----IADSL---QDFWSPDA------EMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPR 139
Cdd:PRK15134 364 iQVVFQDPNSSLNPRLNvlqiIEEGLrvhQPTLSAAQreqqviAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILK 443
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 140 TRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK15134 444 PSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIV 498
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
18-180 |
1.26e-17 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 77.16 E-value: 1.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--------NCGYCPvqlvpQH----PELTfn 85
Cdd:cd03263 19 DDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRtdrkaarqSLGYCP-----QFdalfDELT-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 86 pwrsIADSLQdFWS-----PDAEMMARLHIA------PEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDP 154
Cdd:cd03263 92 ----VREHLR-FYArlkglPKSEIKEEVELLlrvlglTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDP 166
|
170 180
....*....|....*....|....*.
gi 446870191 155 ATQRDVWTFLLELCQRRAlgMVVISH 180
Cdd:cd03263 167 ASRRAIWDLILEVRKGRS--IILTTH 190
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
11-181 |
1.32e-17 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 77.61 E-value: 1.32e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ-------LVPQHPEL- 82
Cdd:cd03256 12 NGKKAL-KDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRqlrrqigMIFQQFNLi 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 ---------------TFNPWRSIADslqdFWSPDA-----EMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRF 142
Cdd:cd03256 91 erlsvlenvlsgrlgRRSTWRSLFG----LFPKEEkqralAALERVGLL-DKAYQRADQLSGGQQQRVAIARALMQQPKL 165
|
170 180 190
....*....|....*....|....*....|....*....
gi 446870191 143 LIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQ 181
Cdd:cd03256 166 ILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQ 204
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
12-180 |
2.03e-17 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 76.89 E-value: 2.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC--PVQLVPQH----PELTFn 85
Cdd:cd03300 11 GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHkrPVNTVFQNyalfPHLTV- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 86 pWRSIADSLQDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRD 159
Cdd:cd03300 90 -FENIAFGLRLKKLPKAEIKERVAEAldlvqlEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKD 168
|
170 180
....*....|....*....|.
gi 446870191 160 VWTFLLELCQRRALGMVVISH 180
Cdd:cd03300 169 MQLELKRLQKELGITFVFVTH 189
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
18-126 |
3.11e-17 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 74.61 E-value: 3.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP----VQLVPQHPELtfNPWRSIAD- 92
Cdd:pfam00005 2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSlrkeIGYVFQDPQL--FPRLTVREn 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 446870191 93 --------SLQDFWSPD--AEMMARL---HIAPEWLTRRPGQLSGGE 126
Cdd:pfam00005 80 lrlglllkGLSKREKDAraEEALEKLglgDLADRPVGERPGTLSGGQ 126
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
10-186 |
3.69e-17 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 76.15 E-value: 3.69e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQK--PLSGEVLVdgkplancgycpvqlvpqhPELTFNPW 87
Cdd:COG2401 39 RVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDV-------------------PDNQFGRE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 88 RSIADSLQDFWSPDAEM----MARLHIAPEWLtRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTF 163
Cdd:COG2401 100 ASLIDAIGRKGDFKDAVellnAVGLSDAVLWL-RRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARN 178
|
170 180
....*....|....*....|...
gi 446870191 164 LLELCQRRALGMVVISHQKALVA 186
Cdd:COG2401 179 LQKLARRAGITLVVATHHYDVID 201
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-194 |
5.40e-17 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 78.18 E-value: 5.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVdGKPLaNCGYcpvqlVPQHP 80
Cdd:COG0488 315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV-KIGY-----FDQHQ 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 ElTFNPWRSIADSLQDfWSPDAE------MMARLHIAPEWLTRRPGQLSGGElarlallraldpRTR------------F 142
Cdd:COG0488 388 E-ELDPDKTVLDELRD-GAPGGTeqevrgYLGRFLFSGDDAFKPVGVLSGGE------------KARlalaklllsppnV 453
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446870191 143 LIADEITAQLDPATQRdvwtfLLElcqrRAL----G-MVVISHQKALVAQVCSSLLV 194
Cdd:COG0488 454 LLLDEPTNHLDIETLE-----ALE----EALddfpGtVLLVSHDRYFLDRVATRILE 501
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-195 |
8.86e-17 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 75.18 E-value: 8.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEkvLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--NCGYCPVQLVPQ 78
Cdd:COG3840 1 MLRLDDLTYRYGD--FPLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTalPPAERPVSMLFQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 79 H----PELTFnpWRSIADSLqdfwSPD-----------AEMMARLHIApEWLTRRPGQLSGGElarlallraldpRTRFL 143
Cdd:COG3840 79 EnnlfPHLTV--AQNIGLGL----RPGlkltaeqraqvEQALERVGLA-GLLDRLPGQLSGGQ------------RQRVA 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 144 IA------------DEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCS-SLLVE 195
Cdd:COG3840 140 LArclvrkrpilllDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADrVLLVA 204
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
19-186 |
1.77e-16 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 73.98 E-value: 1.77e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQLVPQHPELTF---------NPWRS 89
Cdd:cd03292 19 GINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRRKIGVVFqdfrllpdrNVYEN 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 IADSLQDFWSPDAEMMARLHIAPEWLTRR------PGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTf 163
Cdd:cd03292 99 VAFALEVTGVPPREIRKRVPAALELVGLShkhralPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMN- 177
|
170 180
....*....|....*....|...
gi 446870191 164 LLELCQRRALGMVVISHQKALVA 186
Cdd:cd03292 178 LLKKINKAGTTVVVATHAKELVD 200
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
11-181 |
5.42e-16 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 72.20 E-value: 5.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKP--LSGEVLVDGKPL-ANCGYCPVQLVPQ----HPELT 83
Cdd:cd03213 19 KSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlgVSGEVLINGRPLdKRSFRKIIGYVPQddilHPTLT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 fnpwrsIADSLQdfwspdaeMMARLHiapewltrrpgQLSGGElarlallraldpRTR------------FLIADEITAQ 151
Cdd:cd03213 99 ------VRETLM--------FAAKLR-----------GLSGGE------------RKRvsialelvsnpsLLFLDEPTSG 141
|
170 180 190
....*....|....*....|....*....|
gi 446870191 152 LDPATQRDVWTFLLELCQRRALGMVVIsHQ 181
Cdd:cd03213 142 LDSSSALQVMSLLRRLADTGRTIICSI-HQ 170
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
18-187 |
8.42e-16 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 72.50 E-value: 8.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC----PVQLVPQHPELtFNpwRSIADS 93
Cdd:cd03248 31 QDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKylhsKVSLVGQEPVL-FA--RSLQDN 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 94 LQdFWSPDAEMM--------ARLH-----IAPEWLT---RRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQ 157
Cdd:cd03248 108 IA-YGLQSCSFEcvkeaaqkAHAHsfiseLASGYDTevgEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESE 186
|
170 180 190
....*....|....*....|....*....|
gi 446870191 158 RDVWTFLLELCQRRALgmVVISHQKALVAQ 187
Cdd:cd03248 187 QQVQQALYDWPERRTV--LVIAHRLSTVER 214
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
12-194 |
1.47e-15 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 74.01 E-value: 1.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN---------CGYcpvqlVPQHPEL 82
Cdd:COG4618 343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQwdreelgrhIGY-----LPQDVEL 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 tFNPwrSIADSLQDFWSPDAE------MMARLHiapEWLTRRP-----------GQLSGGElarlallraldpRTR---- 141
Cdd:COG4618 418 -FDG--TIAENIARFGDADPEkvvaaaKLAGVH---EMILRLPdgydtrigeggARLSGGQ------------RQRigla 479
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 142 --------FLIADEITAQLDPATQRDVWTFLLELCQRRALgMVVISHQKALVAqVCSSLLV 194
Cdd:COG4618 480 ralygdprLVVLDEPNSNLDDEGEAALAAAIRALKARGAT-VVVITHRPSLLA-AVDKLLV 538
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
18-194 |
1.49e-15 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 71.85 E-value: 1.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL---------ANCGYcpvqlVPQHPELTFNPWR 88
Cdd:cd03245 21 DNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIrqldpadlrRNIGY-----VPQDVTLFYGTLR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 89 S-IADSLQDfwSPDAEMMARLHIA---------PEWLTRRPG----QLSGGELARLALLRALDPRTRFLIADEITAQLDP 154
Cdd:cd03245 96 DnITLGAPL--ADDERILRAAELAgvtdfvnkhPNGLDLQIGergrGLSGGQRQAVALARALLNDPPILLLDEPTSAMDM 173
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446870191 155 ATQRDVWTFLLELCQRRALgmVVISHQKALVaQVCSSLLV 194
Cdd:cd03245 174 NSEERLKERLRQLLGDKTL--IIITHRPSLL-DLVDRIIV 210
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1-182 |
1.74e-15 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 71.67 E-value: 1.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA---------NCGYC 71
Cdd:PRK10247 7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIStlkpeiyrqQVSYC 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 -----------------PVQLVPQHPELTfnpwrSIADSLQDFWSPDaemmarlhiapEWLTRRPGQLSGGELARLALLR 134
Cdd:PRK10247 87 aqtptlfgdtvydnlifPWQIRNQQPDPA-----IFLDDLERFALPD-----------TILTKNIAELSGGEKQRISLIR 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446870191 135 ALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQK 182
Cdd:PRK10247 151 NLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDK 198
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
18-187 |
1.90e-15 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 73.60 E-value: 1.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--NCGYC--PVQLVPQHPELTFNPWR-SIAD 92
Cdd:TIGR00958 498 KGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVqyDHHYLhrQVALVGQEPVLFSGSVReNIAY 577
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 SLQDfwSPDAEMM--ARLHIAPEWLTRRP-----------GQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRd 159
Cdd:TIGR00958 578 GLTD--TPDEEIMaaAKAANAHDFIMEFPngydtevgekgSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQ- 654
|
170 180
....*....|....*....|....*...
gi 446870191 160 vwtFLLELCQRRALGMVVISHQKALVAQ 187
Cdd:TIGR00958 655 ---LLQESRSRASRTVLLIAHRLSTVER 679
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
10-185 |
2.35e-15 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 71.75 E-value: 2.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--NCGYCPVQL-VPQHPELTFNp 86
Cdd:cd03252 11 KPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLAlaDPAWLRRQVgVVLQENVLFN- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 87 wRSIAD--SLQDFWSPDAEMM--ARLHIAPEWLTRRP-------GQ----LSGGELARLALLRALDPRTRFLIADEITAQ 151
Cdd:cd03252 90 -RSIRDniALADPGMSMERVIeaAKLAGAHDFISELPegydtivGEqgagLSGGQRQRIAIARALIHNPRILIFDEATSA 168
|
170 180 190
....*....|....*....|....*....|....
gi 446870191 152 LDPATQRDVWTFLLELCQRRALgmVVISHQKALV 185
Cdd:cd03252 169 LDYESEHAIMRNMHDICAGRTV--IIIAHRLSTV 200
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1-69 |
2.42e-15 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 70.99 E-value: 2.42e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG 69
Cdd:PRK13538 1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQR 69
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-189 |
2.43e-15 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 71.38 E-value: 2.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGycPVQLVP---- 77
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLS--EAELYRlrrr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 78 -----QHPELtFNPWrSIADSLQdFW-----SPDAEMMARlhIAPEWLT---------RRPGQLSGGElarlallraldp 138
Cdd:cd03261 79 mgmlfQSGAL-FDSL-TVFENVA-FPlrehtRLSEEEIRE--IVLEKLEavglrgaedLYPAELSGGM------------ 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 139 RTRFLIA------------DEITAQLDPATQRDVWTFLLELcqRRALGM--VVISHQKALVAQVC 189
Cdd:cd03261 142 KKRVALAralaldpelllyDEPTAGLDPIASGVIDDLIRSL--KKELGLtsIMVTHDLDTAFAIA 204
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
21-194 |
3.03e-15 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 72.30 E-value: 3.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 21 SFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAncGYCP---------VQLVPQHPELTFNPWRSIA 91
Cdd:PRK11308 35 SFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLL--KADPeaqkllrqkIQIVFQNPYGSLNPRKKVG 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 92 DSLQ-------DFWSPD-----AEMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRD 159
Cdd:PRK11308 113 QILEepllintSLSAAErrekaLAMMAKVGLRPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQ 192
|
170 180 190
....*....|....*....|....*....|....*
gi 446870191 160 VWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK11308 193 VLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMV 227
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
2-66 |
3.94e-15 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 70.08 E-value: 3.94e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA 66
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLA 65
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
18-189 |
5.55e-15 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 70.54 E-value: 5.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL-------------ANCGYcpV----QLVPqhp 80
Cdd:COG4181 29 KGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLfaldedararlraRHVGF--VfqsfQLLP--- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 elTFNPWRSIADSLQDFWSPDAEMMARlhiapEWLTR---------RPGQLSGGELARLALLRALDPRTRFLIADEITAQ 151
Cdd:COG4181 104 --TLTALENVMLPLELAGRRDARARAR-----ALLERvglghrldhYPAQLSGGEQQRVALARAFATEPAILFADEPTGN 176
|
170 180 190
....*....|....*....|....*....|....*...
gi 446870191 152 LDPATQRDVWTFLLELCQRRALGMVVISHQKALvAQVC 189
Cdd:COG4181 177 LDAATGEQIIDLLFELNRERGTTLVLVTHDPAL-AARC 213
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
19-180 |
1.31e-14 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 69.68 E-value: 1.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgyCPVQ-----LVPQH----PELTFnpWRS 89
Cdd:cd03296 20 DVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATD---VPVQernvgFVFQHyalfRHMTV--FDN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 IADSLQ----DFWSPDAEMMARLH-----IAPEWLTRR-PGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRD 159
Cdd:cd03296 95 VAFGLRvkprSERPPEAEIRAKVHellklVQLDWLADRyPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKE 174
|
170 180
....*....|....*....|.
gi 446870191 160 VWTFLLELCQRRALGMVVISH 180
Cdd:cd03296 175 LRRWLRRLHDELHVTTVFVTH 195
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
19-181 |
1.73e-14 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 70.85 E-value: 1.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPELtFNPwrSIADSL 94
Cdd:TIGR02868 353 GVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRrrvsVCAQDAHL-FDT--TVRENL 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 95 QdFWSPDA---EMMARLHIA--PEWLTRRPG-----------QLSGGELARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:TIGR02868 430 R-LARPDAtdeELWAALERVglADWLRALPDgldtvlgeggaRLSGGERQRLALARALLADAPILLLDEPTEHLDAETAD 508
|
170 180
....*....|....*....|...
gi 446870191 159 DVWTFLLELCQRRAlgMVVISHQ 181
Cdd:TIGR02868 509 ELLEDLLAALSGRT--VVLITHH 529
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-68 |
2.02e-14 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 68.85 E-value: 2.02e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANC 68
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGL 72
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
11-180 |
6.98e-14 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 67.80 E-value: 6.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGyCPVQLVPQHPELTfnPWRSI 90
Cdd:PRK11248 12 GGKPAL-EDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPG-AERGVVFQNEGLL--PWRNV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 ADS----LQDFWSPDAEmmaRLHIAPEWLT---------RRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQ 157
Cdd:PRK11248 88 QDNvafgLQLAGVEKMQ---RLEIAHQMLKkvglegaekRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTR 164
|
170 180
....*....|....*....|...
gi 446870191 158 RDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK11248 165 EQMQTLLLKLWQETGKQVLLITH 187
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
19-189 |
8.23e-14 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 68.68 E-value: 8.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLV----------DGKPLaNCGYCPVQLVPQHPELTFNPWR 88
Cdd:TIGR03269 302 NVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgdewvdmtKPGPD-GRGRAKRYIGILHQEYDLYPHR 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 89 SIADSLQDFWS---PDA-EMMARLHI----------APEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDP 154
Cdd:TIGR03269 381 TVLDNLTEAIGlelPDElARMKAVITlkmvgfdeekAEEILDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDP 460
|
170 180 190
....*....|....*....|....*....|....*..
gi 446870191 155 ATQRDVWTFLLElcQRRALG--MVVISHQKALVAQVC 189
Cdd:TIGR03269 461 ITKVDVTHSILK--AREEMEqtFIIVSHDMDFVLDVC 495
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-180 |
8.54e-14 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 67.58 E-value: 8.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIR-----QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL----ANCGyc 71
Cdd:COG4525 3 MLTVRHVSVRypgggQPQPAL-QDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVtgpgADRG-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 pvqLVPQHPELTfnPWRSIAD----SLQDFWSPDAEmmaRLHIAPEWL---------TRRPGQLSGGELARLALLRALDP 138
Cdd:COG4525 80 ---VVFQKDALL--PWLNVLDnvafGLRLRGVPKAE---RRARAEELLalvgladfaRRRIWQLSGGMRQRVGIARALAA 151
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446870191 139 RTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:COG4525 152 DPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITH 193
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-126 |
8.80e-14 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 68.20 E-value: 8.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA-------NCGYcpv 73
Cdd:COG3842 5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTglppekrNVGM--- 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446870191 74 qlVPQHPELtFnPWRSIAD----SL-QDFWSPD------AEMMARLHIApEWLTRRPGQLSGGE 126
Cdd:COG3842 82 --VFQDYAL-F-PHLTVAEnvafGLrMRGVPKAeirarvAELLELVGLE-GLADRYPHQLSGGQ 140
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
18-180 |
2.02e-13 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 66.96 E-value: 2.02e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPELTF---NPWRSI 90
Cdd:PRK13635 24 KDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRrqvgMVFQNPDNQFvgaTVQDDV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 ADSLQDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFL 164
Cdd:PRK13635 104 AFGLENIGVPREEMVERVDQAlrqvgmEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETV 183
|
170
....*....|....*.
gi 446870191 165 LELCQRRALGMVVISH 180
Cdd:PRK13635 184 RQLKEQKGITVLSITH 199
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-194 |
2.34e-13 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 67.56 E-value: 2.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP----VQLV 76
Cdd:PRK09536 3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAasrrVASV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 77 PQHPELTFN------------PWRSIADSlqdfWSPD-----AEMMARLHIApEWLTRRPGQLSGGELARLALLRALDPR 139
Cdd:PRK09536 83 PQDTSLSFEfdvrqvvemgrtPHRSRFDT----WTETdraavERAMERTGVA-QFADRPVTSLSGGERQRVLLARALAQA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 140 TRFLIADEITAQLDpaTQRDVWTflLELCQRRA-LGMVVIS--HQKALVAQVCSSLLV 194
Cdd:PRK09536 158 TPVLLLDEPTASLD--INHQVRT--LELVRRLVdDGKTAVAaiHDLDLAARYCDELVL 211
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
18-181 |
2.38e-13 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 65.59 E-value: 2.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLR--PGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC--PVQLVPQHPELTfnPWRSIADS 93
Cdd:cd03298 13 QPMHFDLTfaQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPAdrPVSMLFQENNLF--AHLTVEQN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 94 LQDFWSPD-----------AEMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWT 162
Cdd:cd03298 91 VGLGLSPGlkltaedrqaiEVALARVGLA-GLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLD 169
|
170
....*....|....*....
gi 446870191 163 FLLELCQRRALGMVVISHQ 181
Cdd:cd03298 170 LVLDLHAETKMTVLMVTHQ 188
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-189 |
3.47e-13 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 67.01 E-value: 3.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 4 CRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKplANCGYcpvqlVPQHPELT 83
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKG--LRIGY-----LPQEPPLD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 ------------FNPWRSI--------------------ADSLQDF------WSPDAE---MMARLHIAPEWLTRRPGQL 122
Cdd:COG0488 74 ddltvldtvldgDAELRALeaeleeleaklaepdedlerLAELQEEfealggWEAEARaeeILSGLGFPEEDLDRPVSEL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 123 SGGElarlallraldpRTRFLIA------------DEITAQLD-PATQrdvW--TFLlelcQRRALGMVVISHQKALVAQ 187
Cdd:COG0488 154 SGGW------------RRRVALArallsepdllllDEPTNHLDlESIE---WleEFL----KNYPGTVLVVSHDRYFLDR 214
|
..
gi 446870191 188 VC 189
Cdd:COG0488 215 VA 216
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
11-188 |
4.53e-13 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 64.26 E-value: 4.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC---PVQLVPQHPELtFNPw 87
Cdd:cd03247 13 QEQQVL-KNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKAlssLISVLNQRPYL-FDT- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 88 rSIADSLQDfwspdaemmarlhiapewltrrpgQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLEL 167
Cdd:cd03247 90 -TLRNNLGR------------------------RFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEV 144
|
170 180
....*....|....*....|.
gi 446870191 168 CQRRALgmVVISHQKALVAQV 188
Cdd:cd03247 145 LKDKTL--IWITHHLTGIEHM 163
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
5-180 |
4.62e-13 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 65.28 E-value: 4.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 5 RDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG-----WQKPLSGEVLVDGKPLANCGYCPVQL---- 75
Cdd:cd03260 4 RDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndliPGAPDEGEVLLDGKDIYDLDVDVLELrrrv 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 --VPQHPeltfNPWR-SIADS------LQDFWsPDAEMMARlhiaPEWLTRR------------PGQLSGGELARLALLR 134
Cdd:cd03260 84 gmVFQKP----NPFPgSIYDNvayglrLHGIK-LKEELDER----VEEALRKaalwdevkdrlhALGLSGGQQQRLCLAR 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446870191 135 ALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRAlgMVVISH 180
Cdd:cd03260 155 ALANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYT--IVIVTH 198
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
5-193 |
5.06e-13 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 65.58 E-value: 5.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 5 RDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN---------CGYCPVQL 75
Cdd:PRK10575 15 RNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwsskafarkVAYLPQQL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 vPQHPELTFN--------PWRSiadSLQDFWSPD----AEMMARLHIAPeWLTRRPGQLSGGELARLALLRALDPRTRFL 143
Cdd:PRK10575 95 -PAAEGMTVRelvaigryPWHG---ALGRFGAADrekvEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCL 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446870191 144 IADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLL 193
Cdd:PRK10575 170 LLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLV 219
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-194 |
6.04e-13 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 65.59 E-value: 6.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLL-IRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----L 75
Cdd:PRK13652 3 LIETRDLCySYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRkfvgL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 VPQHPE-LTFNPWRSiadslQDF-WSP-----DAEMMAR-----LHIA--PEWLTRRPGQLSGGELARLALLRALDPRTR 141
Cdd:PRK13652 83 VFQNPDdQIFSPTVE-----QDIaFGPinlglDEETVAHrvssaLHMLglEELRDRVPHHLSGGEKKRVAIAGVIAMEPQ 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446870191 142 FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13652 158 VLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYV 210
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-186 |
7.71e-13 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 64.38 E-value: 7.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--------ANCGycpV 73
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDItglppherARAG---I 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 74 QLVPQH----PELTfnpwrsIADSLQ----------DFWSPDA--EMMARLHiapEWLTRRPGQLSGGELARLALLRALD 137
Cdd:cd03224 78 GYVPEGrrifPELT------VEENLLlgayarrrakRKARLERvyELFPRLK---ERRKQLAGTLSGGEQQMLAIARALM 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446870191 138 PRTRFLIADEITAQLDPATQRDVWTFLLELcqrRALGM-VVISHQKALVA 186
Cdd:cd03224 149 SRPKLLLLDEPSEGLAPKIVEEIFEAIREL---RDEGVtILLVEQNARFA 195
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-181 |
9.20e-13 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 64.09 E-value: 9.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQL------ 75
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINELrqkvgm 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 VPQHpeltFN--PWRSIADSL-----QDFWSPDAEMMARlhiAPEWLTR---------RPGQLSGGElarlallraldpR 139
Cdd:cd03262 81 VFQQ----FNlfPHLTVLENItlapiKVKGMSKAEAEER---ALELLEKvgladkadaYPAQLSGGQ------------Q 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446870191 140 TRFLIA------------DEITAQLDPATQRDVWTFLLELCQrRALGMVVISHQ 181
Cdd:cd03262 142 QRVAIAralamnpkvmlfDEPTSALDPELVGEVLDVMKDLAE-EGMTMVVVTHE 194
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
16-181 |
9.76e-13 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 64.22 E-value: 9.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 16 LWQNL----SFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC--PVQLVPQH----PELTFn 85
Cdd:PRK10771 10 LYHHLpmrfDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSrrPVSMLFQEnnlfSHLTV- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 86 pWRSIADSLQDFWSPDAEMMARL-HIA-----PEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRD 159
Cdd:PRK10771 89 -AQNIGLGLNPGLKLNAAQREKLhAIArqmgiEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQE 167
|
170 180
....*....|....*....|..
gi 446870191 160 VWTFLLELCQRRALGMVVISHQ 181
Cdd:PRK10771 168 MLTLVSQVCQERQLTLLMVSHS 189
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
12-125 |
1.19e-12 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 65.17 E-value: 1.19e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCPVQ-----LVPQHPELtF-- 84
Cdd:COG1118 13 GSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFT--NLPPRerrvgFVFQHYAL-Fph 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 85 -----NpwrsIADSLQDFWSPDAEMMARLHiapEWLT---------RRPGQLSGG 125
Cdd:COG1118 90 mtvaeN----IAFGLRVRPPSKAEIRARVE---ELLElvqlegladRYPSQLSGG 137
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1-180 |
1.65e-12 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 63.68 E-value: 1.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGE-----KVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG------ 69
Cdd:PRK11629 5 LLQCDNLCKRYQEgsvqtDVL-HNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSsaakae 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 70 ---------YCPVQLVPQhpeltFNPWRSIADSLQDFWSPDAEMMARlhiAPEWLT---------RRPGQLSGGELARLA 131
Cdd:PRK11629 84 lrnqklgfiYQFHHLLPD-----FTALENVAMPLLIGKKKPAEINSR---ALEMLAavglehranHRPSELSGGERQRVA 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446870191 132 LLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK11629 156 IARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTH 204
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
19-182 |
2.07e-12 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 64.47 E-value: 2.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG--YCPVQLVPQH----PELTFNpwRSIAD 92
Cdd:PRK11607 37 DVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPpyQRPINMMFQSyalfPHMTVE--QNIAF 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 SL-QDFWSPD------AEMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLL 165
Cdd:PRK11607 115 GLkQDKLPKAeiasrvNEMLGLVHMQ-EFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVV 193
|
170
....*....|....*..
gi 446870191 166 ELCQRRALGMVVISHQK 182
Cdd:PRK11607 194 DILERVGVTCVMVTHDQ 210
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
18-194 |
2.85e-12 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 63.66 E-value: 2.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC----PVQLVPQHPELTFNPWRSIADS 93
Cdd:PRK15112 30 KPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSyrsqRIRMIFQDPSTSLNPRQRISQI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 94 LQ-------DFWSPDAE-----MMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVW 161
Cdd:PRK15112 110 LDfplrlntDLEPEQREkqiieTLRQVGLLPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLI 189
|
170 180 190
....*....|....*....|....*....|...
gi 446870191 162 TFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK15112 190 NLMLELQEKQGISYIYVTQHLGMMKHISDQVLV 222
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
19-194 |
4.16e-12 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 63.69 E-value: 4.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAG------WqkplSGEVLVDGKPLANCGYCPVQ---LVPQHPELTFNPWRS 89
Cdd:TIGR02633 19 GIDLEVRPGECVGLCGENGAGKSTLMKILSGvyphgtW----DGEIYWSGSPLKASNIRDTEragIVIIHQELTLVPELS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 IAD--------SLQDFWSPDAEM-------MARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDP 154
Cdd:TIGR02633 95 VAEniflgneiTLPGGRMAYNAMylraknlLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQARLLILDEPSSSLTE 174
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446870191 155 ATQRDVWTFLLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:TIGR02633 175 KETEILLDIIRDL-KAHGVACVYISHKLNEVKAVCDTICV 213
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
18-179 |
4.57e-12 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 61.68 E-value: 4.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL----------ANCGYCP-----VQLVPQHPeL 82
Cdd:cd03215 17 RDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVtrrsprdairAGIAYVPedrkrEGLVLDLS-V 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 TFNpwRSIADSL-----QDFwspdaeMMARlhiapeWLTRRPgqlsggelarlallraldprtRFLIADEITAQLDPATQ 157
Cdd:cd03215 96 AEN--IALSSLLsggnqQKV------VLAR------WLARDP---------------------RVLILDEPTRGVDVGAK 140
|
170 180
....*....|....*....|..
gi 446870191 158 RDVWTFLLELcQRRALGMVVIS 179
Cdd:cd03215 141 AEIYRLIREL-ADAGKAVLLIS 161
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
21-194 |
5.42e-12 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 63.20 E-value: 5.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 21 SFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--ANCGYC------PVQLVPQHPEL---------- 82
Cdd:COG4148 19 DFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLqdSARGIFlpphrrRIGYVFQEARLfphlsvrgnl 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 TFNPWRS-IADSLQDFwspdAEMMARLHIAPeWLTRRPGQLSGGElarlallraldpRTRFLIA------------DEIT 149
Cdd:COG4148 99 LYGRKRApRAERRISF----DEVVELLGIGH-LLDRRPATLSGGE------------RQRVAIGrallssprlllmDEPL 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446870191 150 AQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG4148 162 AALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVL 206
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
9-194 |
5.49e-12 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 63.19 E-value: 5.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 9 IRQGEKVLWQ---------NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP------- 72
Cdd:PRK15079 20 IKDGKQWFWQppktlkavdGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEwravrsd 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 VQLVPQHPELTFNPWRSIAD-------------SLQDFWSPDAEMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPR 139
Cdd:PRK15079 100 IQMIFQDPLASLNPRMTIGEiiaeplrtyhpklSRQEVKDRVKAMMLKVGLLPNLINRYPHEFSGGQCQRIGIARALILE 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 140 TRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK15079 180 PKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLV 234
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
2-66 |
5.65e-12 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 61.74 E-value: 5.65e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA 66
Cdd:cd03231 1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLD 65
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
10-194 |
6.94e-12 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 61.83 E-value: 6.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGeRLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--------ANCGYCPvQLVPQHPE 81
Cdd:cd03264 9 RYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVlkqpqklrRRIGYLP-QEFGVYPN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 82 LT------FNPW-RSIADSLQDfwSPDAEMMARLHIAPEwLTRRPGQLSGG--ELARLALLRALDPRtrFLIADEITAQL 152
Cdd:cd03264 87 FTvrefldYIAWlKGIPSKEVK--ARVDEVLELVNLGDR-AKKKIGSLSGGmrRRVGIAQALVGDPS--ILIVDEPTAGL 161
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446870191 153 DPATQRDVWTFLLELCQRRalgMVVIS-HQKALVAQVCSSLLV 194
Cdd:cd03264 162 DPEERIRFRNLLSELGEDR---IVILStHIVEDVESLCNQVAV 201
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
11-179 |
1.17e-11 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 61.68 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN----------CGycpvqLVPQHP 80
Cdd:TIGR04520 12 ESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDeenlweirkkVG-----MVFQNP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 ELTFnpwrsIADSLQD---FWS-----PDAEMMARLHIA------PEWLTRRPGQLSGGElarlallraldpRTRFLIA- 145
Cdd:TIGR04520 87 DNQF-----VGATVEDdvaFGLenlgvPREEMRKRVDEAlklvgmEDFRDREPHLLSGGQ------------KQRVAIAg 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446870191 146 -----------DEITAQLDPATQRDVWTFLLELcqRRALGMVVIS 179
Cdd:TIGR04520 150 vlamrpdiiilDEATSMLDPKGRKEVLETIRKL--NKEEGITVIS 192
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
2-194 |
1.21e-11 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 61.30 E-value: 1.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGE-KVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAncGYCPVQLVP--- 77
Cdd:cd03219 1 LEVRGLTKRFGGlVAL-DDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDIT--GLPPHEIARlgi 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 78 ----QHPEL--------------------TFNPWRSiADSLQDFWSPDAEMMARLHIAPEWlTRRPGQLSGGELARLALL 133
Cdd:cd03219 78 grtfQIPRLfpeltvlenvmvaaqartgsGLLLARA-RREEREARERAEELLERVGLADLA-DRPAGELSYGQQRRLEIA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 134 RALDPRTRFLIADEITAQLDPATQRDVWTFLLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03219 156 RALATDPKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTV 215
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
2-157 |
1.25e-11 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 61.20 E-value: 1.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCP----VQLVP 77
Cdd:cd03299 1 LKVENLSKDWKEFKL-KNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITN--LPPekrdISYVP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 78 QH----PELTFnpWRSIADSLQDFWSPDAEMMAR-------LHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIAD 146
Cdd:cd03299 78 QNyalfPHMTV--YKNIAYGLKKRKVDKKEIERKvleiaemLGID-HLLNRKPETLSGGEQQRVAIARALVVNPKILLLD 154
|
170
....*....|.
gi 446870191 147 EITAQLDPATQ 157
Cdd:cd03299 155 EPFSALDVRTK 165
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-181 |
1.29e-11 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 61.25 E-value: 1.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSG-EVLVDGKPLANC---------GY 70
Cdd:COG1119 3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGEdvwelrkriGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 71 CPVQLVPQHPELTfNPWRSIA----DSLQDFWSPDAEMMARlhiAPEWLT---------RRPGQLSGGElarlallrald 137
Cdd:COG1119 83 VSPALQLRFPRDE-TVLDVVLsgffDSIGLYREPTDEQRER---ARELLEllglahladRPFGTLSQGE----------- 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446870191 138 pRTRFLIA------------DEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQ 181
Cdd:COG1119 148 -QRRVLIAralvkdpellilDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHH 202
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
18-188 |
1.56e-11 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 62.18 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK---PLANCGYCPV----QLVPQHPELTFNPWRSI 90
Cdd:PRK10261 341 EKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQridTLSPGKLQALrrdiQFIFQDPYASLDPRQTV 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 ADSLQD------------FWSPDAEMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:PRK10261 421 GDSIMEplrvhgllpgkaAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRG 500
|
170 180 190
....*....|....*....|....*....|
gi 446870191 159 DVWTFLLELCQRRALGMVVISHQKALVAQV 188
Cdd:PRK10261 501 QIINLLLDLQRDFGIAYLFISHDMAVVERI 530
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
10-194 |
1.66e-11 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 60.62 E-value: 1.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK---PLA-NCGYcpvqlvpqHPELT-- 83
Cdd:cd03220 31 EVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRvssLLGlGGGF--------NPELTgr 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 ----FN---------PWRSIADSLQDFwspdAE---------------MMARL------HIAPEwltrrpgqlsggelar 129
Cdd:cd03220 103 eniyLNgrllglsrkEIDEKIDEIIEF----SElgdfidlpvktyssgMKARLafaiatALEPD---------------- 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 130 lallraldprtrFLIADEITAQLDPATQRDVWTFLLELCQRRAlGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03220 163 ------------ILLIDEVLAVGDAAFQEKCQRRLRELLKQGK-TVILVSHDPSSIKRLCDRALV 214
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
19-194 |
1.81e-11 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 61.87 E-value: 1.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAG------WqkplSGEVLVDGKPLANCGYCPVQ---LVPQHPELTFNPWRS 89
Cdd:PRK13549 23 NVSLKVRAGEIVSLCGENGAGKSTLMKVLSGvyphgtY----EGEIIFEGEELQASNIRDTEragIAIIHQELALVKELS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 IADS--LQDFWSP-----DAEMMARlhiAPEWLTR---------RPGQLSGGELARLALLRALDPRTRFLIADEITAQLd 153
Cdd:PRK13549 99 VLENifLGNEITPggimdYDAMYLR---AQKLLAQlkldinpatPVGNLGLGQQQLVEIAKALNKQARLLILDEPTASL- 174
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446870191 154 paTQRDVWTFLLELCQRRALGM--VVISHQKALVAQVCSSLLV 194
Cdd:PRK13549 175 --TESETAVLLDIIRDLKAHGIacIYISHKLNEVKAISDTICV 215
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
12-180 |
1.94e-11 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 60.71 E-value: 1.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgycpVQL---------VPQHPEL 82
Cdd:cd03253 13 GRPVL-KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIRE-----VTLdslrraigvVPQDTVL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 tFNpwRSIADSLQdFWSPDA---EMMA---RLHIAPEWLTRRPG----------QLSGGEL--ARLALLRALDPrtRFLI 144
Cdd:cd03253 87 -FN--DTIGYNIR-YGRPDAtdeEVIEaakAAQIHDKIMRFPDGydtivgerglKLSGGEKqrVAIARAILKNP--PILL 160
|
170 180 190
....*....|....*....|....*....|....*.
gi 446870191 145 ADEITAQLDPATQRDVWTFLLELCQRRALgmVVISH 180
Cdd:cd03253 161 LDEATSALDTHTEREIQAALRDVSKGRTT--IVIAH 194
|
|
| MsbA_rel |
TIGR02204 |
ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ... |
20-185 |
1.97e-11 |
|
ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ATP transporter that exports lipid A and to eukaryotic P-glycoproteins.
Pssm-ID: 131259 [Multi-domain] Cd Length: 576 Bit Score: 62.02 E-value: 1.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLanCGYCP------VQLVPQHPELTFNpwrSIADS 93
Cdd:TIGR02204 359 LNLTVRPGETVALVGPSGAGKSTLFQLLLRFYDPQSGRILLDGVDL--RQLDPaelrarMALVPQDPVLFAA---SVMEN 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 94 LQdFWSPDA-----EMMARLHIAPEWLTRRP-------GQ----LSGGElarlallraldpRTRFLIA------------ 145
Cdd:TIGR02204 434 IR-YGRPDAtdeevEAAARAAHAHEFISALPegydtylGErgvtLSGGQ------------RQRIAIArailkdapilll 500
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446870191 146 DEITAQLDPATQRDVWTFLLELCQRRAlgMVVISHQKALV 185
Cdd:TIGR02204 501 DEATSALDAESEQLVQQALETLMKGRT--TLIIAHRLATV 538
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-193 |
2.55e-11 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 60.49 E-value: 2.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPlANCGYCPVQLVPQH- 79
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLK-VNDPKVDERLIRQEa 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 80 ----------PELT------FNPWRSIADSLQdfwspDAEMMARLHIAPEWLTRR----PGQLSGGELARLALLRALDPR 139
Cdd:PRK09493 80 gmvfqqfylfPHLTalenvmFGPLRVRGASKE-----EAEKQARELLAKVGLAERahhyPSELSGGQQQRVAIARALAVK 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446870191 140 TRFLIADEITAQLDPATQRDVWTFLLELCQrRALGMVVISHQKALVAQVCSSLL 193
Cdd:PRK09493 155 PKLMLFDEPTSALDPELRHEVLKVMQDLAE-EGMTMVIVTHEIGFAEKVASRLI 207
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
18-180 |
2.60e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 60.77 E-value: 2.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP-----VQLVPQHPELTFnPWRSIAD 92
Cdd:PRK13644 19 ENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQgirklVGIVFQNPETQF-VGRTVEE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 SL----QDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWT 162
Cdd:PRK13644 98 DLafgpENLCLPPIEIRKRVDRAlaeiglEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLE 177
|
170
....*....|....*...
gi 446870191 163 FLLELcQRRALGMVVISH 180
Cdd:PRK13644 178 RIKKL-HEKGKTIVYITH 194
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
12-194 |
3.29e-11 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 58.98 E-value: 3.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAncgycpvqlvpqhpeltfnpwrsia 91
Cdd:cd03216 12 GVKAL-DGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVS------------------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 92 dslqdFWSP-DAEmmaRLHIAPEWltrrpgQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELcQR 170
Cdd:cd03216 66 -----FASPrDAR---RAGIAMVY------QLSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFKVIRRL-RA 130
|
170 180
....*....|....*....|....
gi 446870191 171 RALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03216 131 QGVAVIFISHRLDEVFEIADRVTV 154
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-169 |
4.17e-11 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 60.03 E-value: 4.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAncGYCPVQL----- 75
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPIS--MLSSRQLarrla 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 -VPQHP---------ELTF---NPWRSiadslqdFW---SPDAEM-----MARLHIApEWLTRRPGQLSGGELARLALLR 134
Cdd:PRK11231 80 lLPQHHltpegitvrELVAygrSPWLS-------LWgrlSAEDNArvnqaMEQTRIN-HLADRRLTDLSGGQRQRAFLAM 151
|
170 180 190
....*....|....*....|....*....|....*
gi 446870191 135 ALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQ 169
Cdd:PRK11231 152 VLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNT 186
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-194 |
9.43e-11 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 57.07 E-value: 9.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLvdgkplancgycpvqlvpqhpe 81
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVT---------------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 82 ltfnpwrsiadslqdfWSPDAEMmarLHIApewltrrpgQLSGGElarlallraldpRTR------------FLIADEIT 149
Cdd:cd03221 59 ----------------WGSTVKI---GYFE---------QLSGGE------------KMRlalaklllenpnLLLLDEPT 98
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446870191 150 AQLDPATQrdvwTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03221 99 NHLDLESI----EALEEALKEYPGTVILVSHDRYFLDQVATKIIE 139
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
19-194 |
9.53e-11 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 58.46 E-value: 9.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLrPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--ANCGYC-PVQ-----LVPQhpELTFNPWRSI 90
Cdd:cd03297 16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfdSRKKINlPPQqrkigLVFQ--QYALFPHLNV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 ADSL----------QDFWSPDaEMMARLHIAPeWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDV 160
Cdd:cd03297 93 RENLafglkrkrnrEDRISVD-ELLDLLGLDH-LLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQL 170
|
170 180 190
....*....|....*....|....*....|....
gi 446870191 161 WTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03297 171 LPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVV 204
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
18-126 |
1.03e-10 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 59.70 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgycpvqLVPQHpeltfnpwRSIADSLQDF 97
Cdd:COG3839 20 KDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTD-------LPPKD--------RNIAMVFQSY 84
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 98 --------------------WSPD------AEMMARLHIAPeWLTRRPGQLSGGE 126
Cdd:COG3839 85 alyphmtvyeniafplklrkVPKAeidrrvREAAELLGLED-LLDRKPKQLSGGQ 138
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
18-194 |
1.03e-10 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 59.32 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGycPVQL---------VPQHpeltFNPWR 88
Cdd:COG1135 22 DDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALS--ERELraarrkigmIFQH----FNLLS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 89 S------IADSLQDFWSPDAEMMARlhiAPEWLT---------RRPGQLSGGElarlallraldpRTR------------ 141
Cdd:COG1135 96 SrtvaenVALPLEIAGVPKAEIRKR---VAELLElvglsdkadAYPSQLSGGQ------------KQRvgiaralannpk 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446870191 142 FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG1135 161 VLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAV 213
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
19-185 |
1.31e-10 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 59.59 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPELtFNpwRSIADSL 94
Cdd:PRK13657 353 DVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRrniaVVFQDAGL-FN--RSIEDNI 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 95 QdFWSPDA---EMMARLHIAP--EWLTRRPG-----------QLSGGElarlallraldpRTRFLIA------------D 146
Cdd:PRK13657 430 R-VGRPDAtdeEMRAAAERAQahDFIERKPDgydtvvgergrQLSGGE------------RQRLAIArallkdppililD 496
|
170 180 190
....*....|....*....|....*....|....*....
gi 446870191 147 EITAQLDPATQRDVWTFLLELCQRRAlgMVVISHQKALV 185
Cdd:PRK13657 497 EATSALDVETEAKVKAALDELMKGRT--TFIIAHRLSTV 533
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
3-194 |
1.33e-10 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 58.55 E-value: 1.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 3 SCRDLLIRQGEK------VLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK---PLA-NCGYcp 72
Cdd:COG1134 23 SLKELLLRRRRTrreefwAL-KDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRvsaLLElGAGF-- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 vqlvpqHPELT-------------FNPW--RSIADSLQDFwspdAE---------------MMARL------HIAPEwlt 116
Cdd:COG1134 100 ------HPELTgreniylngrllgLSRKeiDEKFDEIVEF----AElgdfidqpvktyssgMRARLafavatAVDPD--- 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 117 rrpgqlsggelarlallraldprtrFLIADEITAQLDPATQRDVWTFLLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG1134 167 -------------------------ILLVDEVLAVGDAAFQKKCLARIREL-RESGRTVIFVSHSMGAVRRLCDRAIW 218
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
20-180 |
1.69e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 58.57 E-value: 1.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPELTF---NPWRSIAD 92
Cdd:PRK13642 26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRrkigMVFQNPDNQFvgaTVEDDVAF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 SLQDFWSPDAEMMARLHIAP------EWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLE 166
Cdd:PRK13642 106 GMENQGIPREEMIKRVDEALlavnmlDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHE 185
|
170
....*....|....
gi 446870191 167 LCQRRALGMVVISH 180
Cdd:PRK13642 186 IKEKYQLTVLSITH 199
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
10-126 |
1.77e-10 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 57.65 E-value: 1.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGycP----VQLVPQ----HPE 81
Cdd:cd03301 9 RFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLP--PkdrdIAMVFQnyalYPH 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 446870191 82 LTFnpWRSIADSLQDFWSPDAEMMAR-------LHIApEWLTRRPGQLSGGE 126
Cdd:cd03301 87 MTV--YDNIAFGLKLRKVPKDEIDERvrevaelLQIE-HLLDRKPKQLSGGQ 135
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
5-180 |
2.00e-10 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 58.42 E-value: 2.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 5 RDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ--------LV 76
Cdd:cd03294 28 EEILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRelrrkkisMV 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 77 PQHPELTfnPWRSIAD----SLQDFWSPDAEMMARLHIAPE------WLTRRPGQLSGG--ELARLALLRALDPrtRFLI 144
Cdd:cd03294 108 FQSFALL--PHRTVLEnvafGLEVQGVPRAEREERAAEALElvglegWEHKYPDELSGGmqQRVGLARALAVDP--DILL 183
|
170 180 190
....*....|....*....|....*....|....*.
gi 446870191 145 ADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:cd03294 184 MDEAFSALDPLIRREMQDELLRLQAELQKTIVFITH 219
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
10-126 |
2.33e-10 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 57.70 E-value: 2.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA---------NCGYCpVQLVPQHP 80
Cdd:cd03295 10 YGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIReqdpvelrrKIGYV-IQQIGLFP 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 81 ELTFnpWRSIA--DSLQDfWSPD------AEMMARLHIAP-EWLTRRPGQLSGGE 126
Cdd:cd03295 89 HMTV--EENIAlvPKLLK-WPKEkireraDELLALVGLDPaEFADRYPHELSGGQ 140
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-170 |
2.84e-10 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 58.28 E-value: 2.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL---ANCGYCPVQLVPQ 78
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVpsrARHARQRVGVVPQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 79 HPELtfNPWRSIADSLQDFWS----PDAEMMARLHIAPEWLT------RRPGQLSGG--ELARLALLRALDPRTrfLIAD 146
Cdd:PRK13537 88 FDNL--DPDFTVRENLLVFGRyfglSAAAARALVPPLLEFAKlenkadAKVGELSGGmkRRLTLARALVNDPDV--LVLD 163
|
170 180
....*....|....*....|....
gi 446870191 147 EITAQLDPATQRDVWTFLLELCQR 170
Cdd:PRK13537 164 EPTTGLDPQARHLMWERLRSLLAR 187
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
12-193 |
2.96e-10 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 58.41 E-value: 2.96e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVdGKplancgycPVQL--VPQHPElTFNP--- 86
Cdd:TIGR03719 333 GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GE--------TVKLayVDQSRD-ALDPnkt 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 87 -WRSIADSLQDFWSPDAEMMARLHIApeWLT-------RRPGQLSGGElarlallraldpRTRFLIA------------D 146
Cdd:TIGR03719 403 vWEEISGGLDIIKLGKREIPSRAYVG--RFNfkgsdqqKKVGQLSGGE------------RNRVHLAktlksggnvlllD 468
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446870191 147 EITAQLDPATQRDVWTFLLELcqrrALGMVVISHQKALVAQVCSSLL 193
Cdd:TIGR03719 469 EPTNDLDVETLRALEEALLNF----AGCAVVISHDRWFLDRIATHIL 511
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-194 |
3.49e-10 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 57.71 E-value: 3.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIR-QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--ANCGYCP----V 73
Cdd:PRK13638 1 MLATSDLWFRyQDEPVL-KGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdySKRGLLAlrqqV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 74 QLVPQHPE--LTFNPWRS-IADSLQDFWSPDAEMMARLHIA-----PEWLTRRPGQ-LSGGELARLALLRALDPRTRFLI 144
Cdd:PRK13638 80 ATVFQDPEqqIFYTDIDSdIAFSLRNLGVPEAEITRRVDEAltlvdAQHFRHQPIQcLSHGQKKRVAIAGALVLQARYLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446870191 145 ADEITAQLDPATQRDVWTFLLELCQrRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13638 160 LDEPTAGLDPAGRTQMIAIIRRIVA-QGNHVIISSHDIDLIYEISDAVYV 208
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
11-187 |
4.80e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 56.71 E-value: 4.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVL--WQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA-------------NCGYC--PV 73
Cdd:PRK10584 18 QGEHELsiLTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHqmdeearaklrakHVGFVfqSF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 74 QLVPqhpelTFNPWRSI-------ADSLQDFWSPDAEMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIAD 146
Cdd:PRK10584 98 MLIP-----TLNALENVelpallrGESSRQSRNGAKALLEQLGLG-KRLDHLPAQLSGGEQQRVALARAFNGRPDVLFAD 171
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446870191 147 EITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQ 187
Cdd:PRK10584 172 EPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAAR 212
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
18-125 |
5.16e-10 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 57.72 E-value: 5.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL----------ANCGYCP----VQ-LVPQHpel 82
Cdd:COG1129 269 RDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVrirsprdairAGIAYVPedrkGEgLVLDL--- 345
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 446870191 83 tfnpwrSIAD-----SLQDFW-----SPDAE------MMARLHIAPEWLTRRPGQLSGG 125
Cdd:COG1129 346 ------SIREnitlaSLDRLSrggllDRRREralaeeYIKRLRIKTPSPEQPVGNLSGG 398
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
19-194 |
5.54e-10 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 57.43 E-value: 5.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKP---LSGEVLVDGKPLANCgycP-----------VQLVPQHPELTF 84
Cdd:PRK09473 34 DLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAAngrIGGSATFNGREILNL---PekelnklraeqISMIFQDPMTSL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 NPWRSIADSL------------QDFWSPDAEMMARLHIaPEWLTRR---PGQLSGGELARLALLRALDPRTRFLIADEIT 149
Cdd:PRK09473 111 NPYMRVGEQLmevlmlhkgmskAEAFEESVRMLDAVKM-PEARKRMkmyPHEFSGGMRQRVMIAMALLCRPKLLIADEPT 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446870191 150 AQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK09473 190 TALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLV 234
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-194 |
5.59e-10 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 57.77 E-value: 5.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIR----QGEKVLWQNLSFSLRPGERLGLSTPSGSGK--TTLG--RVLAGWQKPLSGEVLVDGKPLANCGycP 72
Cdd:COG4172 6 LLSVEDLSVAfgqgGGTVEAVKGVSFDIAAGETLALVGESGSGKsvTALSilRLLPDPAAHPSGSILFDGQDLLGLS--E 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 VQL----------VPQHPELTFNPWRSIADSLqdfwspdAEMMaRLH----------IAPEWLTR------------RPG 120
Cdd:COG4172 84 RELrrirgnriamIFQEPMTSLNPLHTIGKQI-------AEVL-RLHrglsgaaaraRALELLERvgipdperrldaYPH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 121 QLSGGElarlallraldpRTR------------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQV 188
Cdd:COG4172 156 QLSGGQ------------RQRvmiamalanepdLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRF 223
|
....*.
gi 446870191 189 CSSLLV 194
Cdd:COG4172 224 ADRVAV 229
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-194 |
6.52e-10 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 57.04 E-value: 6.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL-----ANCGYCP--- 72
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLdpedrRRIGYLPeer 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 -------V--QLV--------PqhpeltfnpwRSIADSLQDFWspdaemMARLHIApEWLTRRPGQLSGGelarla--ll 133
Cdd:COG4152 81 glypkmkVgeQLVylarlkglS----------KAEAKRRADEW------LERLGLG-DRANKKVEELSKGnqqkvqliaa 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446870191 134 ralDPrtRFLIADEITAQLDPATQRDVWTFLLELCQRralGMVVI--SHQKALVAQVCSSLLV 194
Cdd:COG4152 144 llhDP--ELLILDEPFSGLDPVNVELLKDVIRELAAK---GTTVIfsSHQMELVEELCDRIVI 201
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
2-184 |
7.18e-10 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 55.24 E-value: 7.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGE-KVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG--------WQKPLSGEVLvdgkplancgycp 72
Cdd:cd03223 1 IELENLSLATPDgRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGlwpwgsgrIGMPEGEDLL------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 vqLVPQHPELTFN--------PWrsiadslQDFWSPDaEM----MARLhiapewLTRRPgqlsggelarlallraldprt 140
Cdd:cd03223 68 --FLPQRPYLPLGtlreqliyPW-------DDVLSGG-EQqrlaFARL------LLHKP--------------------- 110
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446870191 141 RFLIADEITAQLDPATQRdvwtFLLELCQRRALGMVVISHQKAL 184
Cdd:cd03223 111 KFVFLDEATSALDEESED----RLYQLLKELGITVISVGHRPSL 150
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
1-186 |
7.29e-10 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 57.51 E-value: 7.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDL-LIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG--------WQKPLSGEVLvdgkplancgyc 71
Cdd:COG4178 362 ALALEDLtLRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGlwpygsgrIARPAGARVL------------ 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 pvqLVPQHPELtfnPWRSIADSL------QDFwsPDAEMMARLHIA--PEWLTR------RPGQLSGGElarlallrald 137
Cdd:COG4178 430 ---FLPQRPYL---PLGTLREALlypataEAF--SDAELREALEAVglGHLAERldeeadWDQVLSLGE----------- 490
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446870191 138 pRTR------------FLIADEITAQLDPATQRDvwtfLLELCQRRALGMVVIS--HQKALVA 186
Cdd:COG4178 491 -QQRlafarlllhkpdWLFLDEATSALDEENEAA----LYQLLREELPGTTVISvgHRSTLAA 548
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
13-194 |
7.72e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 56.59 E-value: 7.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 13 EKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC------PVQLVPQHPELTF-- 84
Cdd:PRK13637 19 EKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKlsdirkKVGLVFQYPEYQLfe 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 -NPWRSIADSLQDFWSPDAEMMARLHIAPE--------WLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPA 155
Cdd:PRK13637 99 eTIEKDIAFGPINLGLSEEEIENRVKRAMNivgldyedYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPK 178
|
170 180 190
....*....|....*....|....*....|....*....
gi 446870191 156 TQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13637 179 GRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIV 217
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
11-189 |
8.49e-10 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 55.90 E-value: 8.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVL--WQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLV--DGKP--LANC-------------GYc 71
Cdd:COG4778 19 QGGKRLpvLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrhDGGWvdLAQAspreilalrrrtiGY- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 pvqlVPQHpeLTFNPWRS----IADSLQDFWSPDAEMMARlhiAPEWLTR----------RPGQLSGGELARLALLRALD 137
Cdd:COG4778 98 ----VSQF--LRVIPRVSaldvVAEPLLERGVDREEARAR---ARELLARlnlperlwdlPPATFSGGEQQRVNIARGFI 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446870191 138 PRTRFLIADEITAQLDPATQRDVWTFLLELCQRRAlGMVVISHQKALVAQVC 189
Cdd:COG4778 169 ADPPLLLLDEPTASLDAANRAVVVELIEEAKARGT-AIIGIFHDEEVREAVA 219
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
12-126 |
9.51e-10 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 56.88 E-value: 9.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYC--PVQLVPQH----PELTFn 85
Cdd:PRK09452 25 DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAEnrHVNTVFQSyalfPHMTV- 103
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 446870191 86 pWRSIADSLQDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGE 126
Cdd:PRK09452 104 -FENVAFGLRMQKTPAAEITPRVMEAlrmvqlEEFAQRKPHQLSGGQ 149
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1-194 |
1.30e-09 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 56.64 E-value: 1.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLI--RQGEKV--LWQNLSFSLRPGERLGLSTPSGSGKT-TLGRVLAGWQKP----LSGEVLVDGKPLANCGYC 71
Cdd:PRK15134 5 LLAIENLSVafRQQQTVrtVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLLHASEQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 PVQ--------LVPQHPELTFNPWRSIADSLQDFWS---------PDAEMMARL-----HIAPEWLTRRPGQLSGGELAR 129
Cdd:PRK15134 85 TLRgvrgnkiaMIFQEPMVSLNPLHTLEKQLYEVLSlhrgmrreaARGEILNCLdrvgiRQAAKRLTDYPHQLSGGERQR 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 130 LALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK15134 165 VMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAV 229
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
13-179 |
1.33e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 55.89 E-value: 1.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 13 EKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPELTF---N 85
Cdd:PRK13650 19 EKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRhkigMVFQNPDNQFvgaT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 86 PWRSIADSLQDFWSPDAEMMARLHIAPEWL------TRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRD 159
Cdd:PRK13650 99 VEDDVAFGLENKGIPHEEMKERVNEALELVgmqdfkEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLE 178
|
170 180
....*....|....*....|
gi 446870191 160 VWTFLLELcqRRALGMVVIS 179
Cdd:PRK13650 179 LIKTIKGI--RDDYQMTVIS 196
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-188 |
1.33e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 55.69 E-value: 1.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG----WQKP-LSGEVLVDGKPLANCGYCP---- 72
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRlielYPEArVSGEVYLDGQDIFKMDVIElrrr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 73 VQLVPQ--HPELTFNPWRSIA--DSLQDFWSPDAEMMARLHIAPE----W------LTRRPGQLSGGELARLALLRALDP 138
Cdd:PRK14247 84 VQMVFQipNPIPNLSIFENVAlgLKLNRLVKSKKELQERVRWALEkaqlWdevkdrLDAPAGKLSGGQQQRLCIARALAF 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446870191 139 RTRFLIADEITAQLDPATQRDVWTFLLELcqRRALGMVVISHQKALVAQV 188
Cdd:PRK14247 164 QPEVLLADEPTANLDPENTAKIESLFLEL--KKDMTIVLVTHFPQQAARI 211
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
12-180 |
1.80e-09 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 56.18 E-value: 1.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--------NCGycpVQLVPQhpELT 83
Cdd:COG1129 16 GVKAL-DGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRfrsprdaqAAG---IAIIHQ--ELN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 FNPWRSIADSL------QDFWSPD--------AEMMARL--HIAPewlTRRPGQLSGGElarlallraldpR-------- 139
Cdd:COG1129 90 LVPNLSVAENIflgrepRRGGLIDwramrrraRELLARLglDIDP---DTPVGDLSVAQ------------Qqlveiara 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446870191 140 ----TRFLIADEITAQLDPA-TQRdvwtfLLELCQR-RALGMVV--ISH 180
Cdd:COG1129 155 lsrdARVLILDEPTASLTEReVER-----LFRIIRRlKAQGVAIiyISH 198
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
1-180 |
2.18e-09 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 54.80 E-value: 2.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKP---LSGEVLVDGKPLANcgyCPVQ--- 74
Cdd:COG4136 1 MLSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRLTA---LPAEqrr 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 75 --LVPQHPELtfNPWRSIADSLQDFWSPDAEMMARLHIAPEWLT---------RRPGQLSGGElarlallraldpRTR-- 141
Cdd:COG4136 78 igILFQDDLL--FPHLSVGENLAFALPPTIGRAQRRARVEQALEeaglagfadRDPATLSGGQ------------RARva 143
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446870191 142 ----------FLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:COG4136 144 llrallaeprALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTH 192
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
10-180 |
2.45e-09 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 55.38 E-value: 2.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--ANCGYC--PVQLVPQHPELTF- 84
Cdd:PRK13632 18 PNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITIskENLKEIrkKIGIIFQNPDNQFi 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 --NPWRSIADSLQDFWSPDAEMMAR-LHIAP-----EWLTRRPGQLSGGELA--RLALLRALDPRtrFLIADEITAQLDP 154
Cdd:PRK13632 98 gaTVEDDIAFGLENKKVPPKKMKDIiDDLAKkvgmeDYLDKEPQNLSGGQKQrvAIASVLALNPE--IIIFDESTSMLDP 175
|
170 180
....*....|....*....|....*.
gi 446870191 155 ATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK13632 176 KGKREIKKIMVDLRKTRKKTLISITH 201
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
18-181 |
3.61e-09 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 54.20 E-value: 3.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTL-----GRVLAGwqKPLSGEVLVDGKPLA------NCGYcpvqlVPQ----HPEL 82
Cdd:cd03234 24 NDVSLHVESGQVMAILGSSGSGKTTLldaisGRVEGG--GTTSGQILFNGQPRKpdqfqkCVAY-----VRQddilLPGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 TF---------NPWRSIADSLQDFWSPDAEMMARLHIAPEWLTRRPGqLSGGEL--ARLALLRALDPrtRFLIADEITAQ 151
Cdd:cd03234 97 TVretltytaiLRLPRKSSDAIRKKRVEDVLLRDLALTRIGGNLVKG-ISGGERrrVSIAVQLLWDP--KVLILDEPTSG 173
|
170 180 190
....*....|....*....|....*....|
gi 446870191 152 LDPATQRDVWTFLLELCQRRALGMVVIsHQ 181
Cdd:cd03234 174 LDSFTALNLVSTLSQLARRNRIVILTI-HQ 202
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
6-178 |
4.08e-09 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 54.30 E-value: 4.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 6 DLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG--------KPLANCGYcpvqlVP 77
Cdd:cd03265 5 NLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGhdvvreprEVRRRIGI-----VF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 78 QHPeltfnpwrSIADSLQDFwsPDAEMMARLHIAP-EWLTRRPGQL-----------------SGGELARLALLRALDPR 139
Cdd:cd03265 80 QDL--------SVDDELTGW--ENLYIHARLYGVPgAERRERIDELldfvglleaadrlvktySGGMRRRLEIARSLVHR 149
|
170 180 190
....*....|....*....|....*....|....*....
gi 446870191 140 TRFLIADEITAQLDPATQRDVWTFLLELcqRRALGMVVI 178
Cdd:cd03265 150 PEVLFLDEPTIGLDPQTRAHVWEYIEKL--KEEFGMTIL 186
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
19-180 |
4.33e-09 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 55.21 E-value: 4.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANC---------GycpvqLVPQHPELtFNpwRS 89
Cdd:COG5265 376 GVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVtqaslraaiG-----IVPQDTVL-FN--DT 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 IADSLQdFWSPDAEM--------MARLH--IA--PE-WLTR---RPGQLSGGElarlallraldpRTRFLIA-------- 145
Cdd:COG5265 448 IAYNIA-YGRPDASEeeveaaarAAQIHdfIEslPDgYDTRvgeRGLKLSGGE------------KQRVAIArtllknpp 514
|
170 180 190
....*....|....*....|....*....|....*....
gi 446870191 146 ----DEITAQLDPATQRDVWTFLLELCQRRAlgMVVISH 180
Cdd:COG5265 515 ilifDEATSALDSRTERAIQAALREVARGRT--TLVIAH 551
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
2-194 |
6.55e-09 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 54.45 E-value: 6.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVlwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG-WQKPLSGEVLVDGKPLA--NC---------- 68
Cdd:TIGR02633 263 LTCWDVINPHRKRV--DDVSFSLRRGEILGVAGLVGAGRTELVQALFGaYPGKFEGNVFINGKPVDirNPaqairagiam 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 69 --------GYCPVQLVPQHPELT-FNPW--RSIADSLQDFWSPDAEmMARLHIApewlTRRP----GQLSGGELARLALL 133
Cdd:TIGR02633 341 vpedrkrhGIVPILGVGKNITLSvLKSFcfKMRIDAAAELQIIGSA-IQRLKVK----TASPflpiGRLSGGNQQKAVLA 415
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 134 RALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQrRALGMVVISHQKALVAQVCSSLLV 194
Cdd:TIGR02633 416 KMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQ-EGVAIIVVSSELAEVLGLSDRVLV 475
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
18-194 |
7.00e-09 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 54.48 E-value: 7.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQL------------------VPQH 79
Cdd:PRK10261 33 RNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSRQVIELseqsaaqmrhvrgadmamIFQE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 80 PELTFNP----WRSIADSL---QDFWSPDA-----EMMARLHI--APEWLTRRPGQLSGGELARLALLRALDPRTRFLIA 145
Cdd:PRK10261 113 PMTSLNPvftvGEQIAESIrlhQGASREEAmveakRMLDQVRIpeAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLIA 192
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446870191 146 DEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK10261 193 DEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLV 241
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
18-189 |
7.24e-09 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 54.04 E-value: 7.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGycPVQL---------VPQHpeltFNPWR 88
Cdd:PRK11153 22 NNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALS--EKELrkarrqigmIFQH----FNLLS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 89 S------IADSLQDFWSPDAEMMARLHiapEWLT---------RRPGQLSGGElarlallraldpRTRFLIA-------- 145
Cdd:PRK11153 96 SrtvfdnVALPLELAGTPKAEIKARVT---ELLElvglsdkadRYPAQLSGGQ------------KQRVAIAralasnpk 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446870191 146 ----DEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVC 189
Cdd:PRK11153 161 vllcDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRIC 208
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
20-194 |
8.64e-09 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 54.29 E-value: 8.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGycPVQ-------LVPQHPELtFnPWRSIAD 92
Cdd:PRK15439 30 IDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLT--PAKahqlgiyLVPQEPLL-F-PNLSVKE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 SL-------QDFWSPDAEMMARL--HIAPEWLTrrpGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTF 163
Cdd:PRK15439 106 NIlfglpkrQASMQKMKQLLAALgcQLDLDSSA---GSLEVADRQIVEILRGLMRDSRILILDEPTASLTPAETERLFSR 182
|
170 180 190
....*....|....*....|....*....|.
gi 446870191 164 LLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK15439 183 IREL-LAQGVGIVFISHKLPEIRQLADRISV 212
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
12-180 |
9.17e-09 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 53.39 E-value: 9.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP----VQLVPQHPELtFNPw 87
Cdd:cd03251 14 GPPVL-RDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASlrrqIGLVSQDVFL-FND- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 88 rSIADSLQdFWSPDAEM-----MARLHIAPEWLTRRPG-----------QLSGGELARLA--LLRALDPrtRFLIADEIT 149
Cdd:cd03251 91 -TVAENIA-YGRPGATReeveeAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAiaRALLKDP--PILILDEAT 166
|
170 180 190
....*....|....*....|....*....|.
gi 446870191 150 AQLDPATQRDVWTFLLELCQRRAlgMVVISH 180
Cdd:cd03251 167 SALDTESERLVQAALERLMKNRT--TFVIAH 195
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
20-194 |
1.19e-08 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 52.76 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG-----KPLA---NCGycpvqLVPQHPELTfnPWRSIA 91
Cdd:cd03266 24 VSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGfdvvkEPAEarrRLG-----FVSDSTGLY--DRLTAR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 92 DSLQDF-----WSPDA------EMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDV 160
Cdd:cd03266 97 ENLEYFaglygLKGDEltarleELADRLGME-ELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRAL 175
|
170 180 190
....*....|....*....|....*....|....*.
gi 446870191 161 WTFLLELcqrRALGMVVI--SHQKALVAQVCSSLLV 194
Cdd:cd03266 176 REFIRQL---RALGKCILfsTHIMQEVERLCDRVVV 208
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
13-194 |
1.46e-08 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 52.72 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 13 EKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG--------KPLANCGYcpvqLVPQHPELTF 84
Cdd:cd03267 33 EVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGlvpwkrrkKFLRRIGV----VFGQKTQLWW 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 NpwRSIADS---LQDFWS-PDAEMMAR-------LHIAPEwLTRRPGQLSGGELARLALLRAL--DPRTRFLiaDEITAQ 151
Cdd:cd03267 109 D--LPVIDSfylLAAIYDlPPARFKKRldelselLDLEEL-LDTPVRQLSLGQRMRAEIAAALlhEPEILFL--DEPTIG 183
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446870191 152 LDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:cd03267 184 LDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLV 226
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
11-180 |
1.49e-08 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 53.29 E-value: 1.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLA-GWQkPLSGEVLVDGKPLANcgYCPVQL------VPQHPELt 83
Cdd:PRK11160 351 QPQPVL-KGLSLQIKAGEKVALLGRTGCGKSTLLQLLTrAWD-PQQGEILLNGQPIAD--YSEAALrqaisvVSQRVHL- 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 FNPwrSIADSLQdFWSP---DAEMMARL-------HIAPE-----WLTRRPGQLSGGElarlallraldpRTRFLIA--- 145
Cdd:PRK11160 426 FSA--TLRDNLL-LAAPnasDEALIEVLqqvglekLLEDDkglnaWLGEGGRQLSGGE------------QRRLGIAral 490
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446870191 146 ---------DEITAQLDPATQRDVWTFLLELCQRRALgmVVISH 180
Cdd:PRK11160 491 lhdapllllDEPTEGLDAETERQILELLAEHAQNKTV--LMITH 532
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1-66 |
1.85e-08 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 52.68 E-value: 1.85e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA 66
Cdd:PRK11300 5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIE 70
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-180 |
1.90e-08 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 53.27 E-value: 1.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQ--KPLSGEVLVdgkplaNCGYCPVQLVPQH 79
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIIY------HVALCEKCGYVER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 80 PELTFNPWRSIADSLQ----DFWSPD-----------AEMMAR------------------------------------- 107
Cdd:TIGR03269 75 PSKVGEPCPVCGGTLEpeevDFWNLSdklrrrirkriAIMLQRtfalygddtvldnvlealeeigyegkeavgravdlie 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 108 --------LHIAPEwltrrpgqLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVIS 179
Cdd:TIGR03269 155 mvqlshriTHIARD--------LSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTS 226
|
.
gi 446870191 180 H 180
Cdd:TIGR03269 227 H 227
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
12-180 |
2.01e-08 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 52.23 E-value: 2.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL---------ANCGYcpvqlVPQHPEL 82
Cdd:cd03254 15 KKPVL-KDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIrdisrkslrSMIGV-----VLQDTFL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 tFNpwRSIADSLqDFWSPDAEM-----MARLHIAPEWLTRRP-----------GQLSGGELARLALLRALDPRTRFLIAD 146
Cdd:cd03254 89 -FS--GTIMENI-RLGRPNATDeevieAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILILD 164
|
170 180 190
....*....|....*....|....*....|....
gi 446870191 147 EITAQLDPATQRDVWTFLLELCQRRALgmVVISH 180
Cdd:cd03254 165 EATSNIDTETEKLIQEALEKLMKGRTS--IIIAH 196
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-63 |
2.34e-08 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 51.83 E-value: 2.34e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK 63
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGK 62
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
12-194 |
2.63e-08 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 52.53 E-value: 2.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL---ANCGYCPVQLVPQ----HPELT- 83
Cdd:PRK13536 52 GDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVparARLARARIGVVPQfdnlDLEFTv 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 ------FNPW--------RSIADSLQDFwspdaemmARLHIAPEwltRRPGQLSGG--ELARLALLRALDPrtRFLIADE 147
Cdd:PRK13536 132 renllvFGRYfgmstreiEAVIPSLLEF--------ARLESKAD---ARVSDLSGGmkRRLTLARALINDP--QLLILDE 198
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446870191 148 ITAQLDPATQRDVWTFLLELCqrrALGMVVI--SHQKALVAQVCSSLLV 194
Cdd:PRK13536 199 PTTGLDPHARHLIWERLRSLL---ARGKTILltTHFMEEAERLCDRLCV 244
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
20-194 |
3.15e-08 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 52.71 E-value: 3.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--------ANCGYCPvQLVPQHPELTFNPWRSIA 91
Cdd:TIGR01257 1958 LCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIltnisdvhQNMGYCP-QFDAIDDLLTGREHLYLY 2036
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 92 DSLQDFWSPDAEMMARLHIAPEWLT----RRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLEL 167
Cdd:TIGR01257 2037 ARLRGVPAEEIEKVANWSIQSLGLSlyadRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSI 2116
|
170 180
....*....|....*....|....*..
gi 446870191 168 CqRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:TIGR01257 2117 I-REGRAVVLTSHSMEECEALCTRLAI 2142
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
12-60 |
3.20e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 52.43 E-value: 3.20e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLV 60
Cdd:PRK11819 335 GDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI 383
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
18-179 |
3.80e-08 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 51.76 E-value: 3.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQkPLSGEVLVDGKPLAncGYCPVQL------VPQHPELTFN-P-WRS 89
Cdd:COG4138 13 GPISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLS--DWSAAELarhrayLSQQQSPPFAmPvFQY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 90 IADSLQDFWSPD------AEMMARLHIAPEwLTRRPGQLSGGE-------LARLALLRALDPRTRFLIADEITAQLDPAT 156
Cdd:COG4138 90 LALHQPAGASSEaveqllAQLAEALGLEDK-LSRPLTQLSGGEwqrvrlaAVLLQVWPTINPEGQLLLLDEPMNSLDVAQ 168
|
170 180
....*....|....*....|...
gi 446870191 157 QRDVWTFLLELCQrrALGMVVIS 179
Cdd:COG4138 169 QAALDRLLRELCQ--QGITVVMS 189
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
18-194 |
3.94e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 51.77 E-value: 3.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL-----------ANCGYcpVQLVPQHPELTFNP 86
Cdd:PRK13636 23 KGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdysrkglmklrESVGM--VFQDPDNQLFSASV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 87 WRSIADSLQDFWSPDAEM-------MARLHIAPewLTRRPGQ-LSGGELARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:PRK13636 101 YQDVSFGAVNLKLPEDEVrkrvdnaLKRTGIEH--LKDKPTHcLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVS 178
|
170 180 190
....*....|....*....|....*....|....*.
gi 446870191 159 DVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13636 179 EIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFV 214
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
119-194 |
4.16e-08 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 52.05 E-value: 4.16e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446870191 119 PGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK11022 151 PHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIV 226
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-180 |
4.17e-08 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 51.53 E-value: 4.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGE-KVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQL---- 75
Cdd:COG1126 1 MIEIENLHKSFGDlEVL-KGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINKLrrkv 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 76 --VPQHpeltFN--PWRSIADSLqdfwspdaeMMARLH-----------IAPEWLTR---------RPGQLSGGElarla 131
Cdd:COG1126 80 gmVFQQ----FNlfPHLTVLENV---------TLAPIKvkkmskaeaeeRAMELLERvgladkadaYPAQLSGGQ----- 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 132 llraldpRTRFLIA------------DEITAQLDPATQRDVWTFLLELcQRRALGMVVISH 180
Cdd:COG1126 142 -------QQRVAIAralamepkvmlfDEPTSALDPELVGEVLDVMRDL-AKEGMTMVVVTH 194
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-63 |
4.35e-08 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 51.47 E-value: 4.35e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK 63
Cdd:PRK11701 6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMR 68
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
4-83 |
5.05e-08 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 50.70 E-value: 5.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 4 CRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGW--QKPLSGEVLVDGKPLANC-----GYCPVQLV 76
Cdd:cd03232 10 NYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRktAGVITGEILINGRPLDKNfqrstGYVEQQDV 89
|
....*...
gi 446870191 77 pqH-PELT 83
Cdd:cd03232 90 --HsPNLT 95
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-180 |
5.61e-08 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 51.00 E-value: 5.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN----------CGYc 71
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKlpmhkrarlgIGY- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 pvqlVPQHP----ELTF--NpwrsIADSLQDFWSPDAEMMARL-------HIAPewLTRRPG-QLSGGELARLALLRALD 137
Cdd:cd03218 80 ----LPQEAsifrKLTVeeN----ILAVLEIRGLSKKEREEKLeelleefHITH--LRKSKAsSLSGGERRRVEIARALA 149
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446870191 138 PRTRFLIADEITAQLDPATQRDVWTFLLELcQRRALGMVVISH 180
Cdd:cd03218 150 TNPKFLLLDEPFAGVDPIAVQDIQKIIKIL-KDRGIGVLITDH 191
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
20-180 |
5.90e-08 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 51.09 E-value: 5.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGwQKPLSGEVLVDGKPLAncGYCPVQLV--------PQHPELTFNPWRSIA 91
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGQPLE--AWSAAELArhraylsqQQTPPFAMPVFQYLT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 92 DSLQDFWSPDA------EMMARLHIAPEwLTRRPGQLSGGE-------LARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:PRK03695 92 LHQPDKTRTEAvasalnEVAEALGLDDK-LGRSVNQLSGGEwqrvrlaAVVLQVWPDINPAGQLLLLDEPMNSLDVAQQA 170
|
170 180
....*....|....*....|..
gi 446870191 159 DVWTFLLELCQrRALGMVVISH 180
Cdd:PRK03695 171 ALDRLLSELCQ-QGIAVVMSSH 191
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
18-83 |
6.91e-08 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 51.45 E-value: 6.91e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--------NCG----YCPVQLVpqhPELT 83
Cdd:PRK11288 21 DDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRfasttaalAAGvaiiYQELHLV---PEMT 95
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
6-184 |
7.31e-08 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 51.67 E-value: 7.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 6 DLLIRQGEkVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG-WqkPLSGEVLVDGKPlancgyCPVQLVPQHPELTF 84
Cdd:TIGR00954 458 PLVTPNGD-VLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGElW--PVYGGRLTKPAK------GKLFYVPQRPYMTL 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 NPWRS---IADSLQDFWS---PDAEMMARL------HIapewLTRRPG---------QLSGGELARLALLRALDPRTRFL 143
Cdd:TIGR00954 529 GTLRDqiiYPDSSEDMKRrglSDKDLEQILdnvqltHI----LEREGGwsavqdwmdVLSGGEKQRIAMARLFYHKPQFA 604
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446870191 144 IADEITAQLDPatqrDVWTFLLELCQRRALGMVVISHQKAL 184
Cdd:TIGR00954 605 ILDECTSAVSV----DVEGYMYRLCREFGITLFSVSHRKSL 641
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
13-156 |
7.79e-08 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 50.49 E-value: 7.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 13 EKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPELTFNPWR 88
Cdd:cd03369 21 PPVL-KNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRssltIIPQDPTLFSGTIR 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 89 SIADSLQDFwsPDAEMMARLHIAPEWLtrrpgQLSGGELARLALLRALDPRTRFLIADEITAQLDPAT 156
Cdd:cd03369 100 SNLDPFDEY--SDEEIYGALRVSEGGL-----NLSQGQRQLLCLARALLKRPRVLVLDEATASIDYAT 160
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
2-67 |
8.51e-08 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 51.18 E-value: 8.51e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446870191 2 LSCRDlliRQGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN 67
Cdd:COG3845 263 LSVRD---DRGVPAL-KDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITG 324
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
10-62 |
1.31e-07 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 50.49 E-value: 1.31e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG 62
Cdd:PRK11432 15 RFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDG 67
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
19-194 |
1.40e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 50.21 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL-ANCG-------YCPVQLVPQHPE--------- 81
Cdd:PRK13641 25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItPETGnknlkklRKKVSLVFQFPEaqlfentvl 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 82 --LTFNPwRSIADSLQDFWSPDAEMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRD 159
Cdd:PRK13641 105 kdVEFGP-KNFGFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKE 183
|
170 180 190
....*....|....*....|....*....|....*
gi 446870191 160 VWTFLLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13641 184 MMQLFKDY-QKAGHTVILVTHNMDDVAEYADDVLV 217
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
14-187 |
1.43e-07 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 50.49 E-value: 1.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 14 KVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANC-GYCPVQLVPQHPELTFNPWRSIA- 91
Cdd:PRK10535 22 EVL-KGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLdADALAQLRREHFGFIFQRYHLLSh 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 92 -DSLQDFWSP----DAEMMARLHIAPEWLTR---------RPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQ 157
Cdd:PRK10535 101 lTAAQNVEVPavyaGLERKQRLLRAQELLQRlgledrveyQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSG 180
|
170 180 190
....*....|....*....|....*....|..
gi 446870191 158 RDVWTFLLELCQRralGMVVI--SHQKALVAQ 187
Cdd:PRK10535 181 EEVMAILHQLRDR---GHTVIivTHDPQVAAQ 209
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
18-194 |
2.17e-07 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 49.70 E-value: 2.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGkplancgycpvqlvpqhpeltFNPWR--------- 88
Cdd:COG4586 39 DDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLG---------------------YVPFKrrkefarri 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 89 --------------SIADS---LQDFWS-PDA-------EMMARLHIAPewLTRRP-GQLSGGElarlallraldpRTRF 142
Cdd:COG4586 98 gvvfgqrsqlwwdlPAIDSfrlLKAIYRiPDAeykkrldELVELLDLGE--LLDTPvRQLSLGQ------------RMRC 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446870191 143 -LIA-----------DEITAQLDPATQRDVWTFLLELCQRRalGMVVI--SHQKALVAQVCSSLLV 194
Cdd:COG4586 164 eLAAallhrpkilflDEPTIGLDVVSKEAIREFLKEYNRER--GTTILltSHDMDDIEALCDRVIV 227
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
10-126 |
3.10e-07 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 49.08 E-value: 3.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANcgYCP------VQLVPQHPELt 83
Cdd:cd03249 13 RPDVPIL-KGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRD--LNLrwlrsqIGLVSQEPVL- 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 84 FNpwRSIAD--SLQDFWSPDAEMM--ARLHIAPEWLTRRP-----------GQLSGGE 126
Cdd:cd03249 89 FD--GTIAEniRYGKPDATDEEVEeaAKKANIHDFIMSLPdgydtlvgergSQLSGGQ 144
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
12-108 |
3.26e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 49.55 E-value: 3.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDgkPLANCGYcpvqlVPQHPEL--TFNPWRS 89
Cdd:TIGR03719 16 PKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQ--PGIKVGY-----LPQEPQLdpTKTVREN 88
|
90 100 110
....*....|....*....|....*....|....*....
gi 446870191 90 IADSLQD--------------FWSPDAEM------MARL 108
Cdd:TIGR03719 89 VEEGVAEikdaldrfneisakYAEPDADFdklaaeQAEL 127
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
23-158 |
4.66e-07 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 48.56 E-value: 4.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 23 SLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAncgYCPVQLVPQHPELTFNPWRSIADSL--QDFWsp 100
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS---YKPQYIKADYEGTVRDLLSSITKDFytHPYF-- 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 101 DAEMMARLHIAPeWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDpATQR 158
Cdd:cd03237 96 KTEIAKPLQIEQ-ILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLD-VEQR 151
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
10-181 |
5.24e-07 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 48.89 E-value: 5.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKP---LSGEVLVDGKPL------ANCGY-------CPV 73
Cdd:TIGR00955 34 ERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPIdakemrAISAYvqqddlfIPT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 74 QLVPQHpeLTFnpwrSIADSLQDFWSPDAEM--------MARLHIAPEWLTRRPGQ---LSGGEL--ARLALLRALDPrt 140
Cdd:TIGR00955 114 LTVREH--LMF----QAHLRMPRRVTKKEKRervdevlqALGLRKCANTRIGVPGRvkgLSGGERkrLAFASELLTDP-- 185
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446870191 141 RFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVIsHQ 181
Cdd:TIGR00955 186 PLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTI-HQ 225
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
18-180 |
5.95e-07 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 48.87 E-value: 5.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA--------NCGycpVQLVPQH----PELT-- 83
Cdd:COG3845 22 DDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRirsprdaiALG---IGMVHQHfmlvPNLTva 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 -------------FNPWRSIADSLQdfwspdaEMMAR--LHIAPEwltRRPGQLSGGElarlallraldpR--------- 139
Cdd:COG3845 99 enivlgleptkggRLDRKAARARIR-------ELSERygLDVDPD---AKVEDLSVGE------------Qqrveilkal 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446870191 140 ---TRFLIADEITAQLDPATQRDVWTFLLELcqrRALGM--VVISH 180
Cdd:COG3845 157 yrgARILILDEPTAVLTPQEADELFEILRRL---AAEGKsiIFITH 199
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
36-194 |
6.50e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 48.48 E-value: 6.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 36 SGSGKTTLGRVLAGWQKPLSGEVLV------------DGKPLANcgycPVQLVPQHPE-----------LTFNPwrsiad 92
Cdd:PRK13634 42 TGSGKSTLLQHLNGLLQPTSGTVTIgervitagkknkKLKPLRK----KVGIVFQFPEhqlfeetvekdICFGP------ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 slQDFWSPDA-------EMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLL 165
Cdd:PRK13634 112 --MNFGVSEEdakqkarEMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFY 189
|
170 180
....*....|....*....|....*....
gi 446870191 166 ELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13634 190 KLHKEKGLTTVLVTHSMEDAARYADQIVV 218
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
18-181 |
7.20e-07 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 48.56 E-value: 7.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGER----LGLSTPS----------GSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP----VQLVPQH 79
Cdd:PRK10790 344 DNVSFAYRDDNLvlqnINLSVPSrgfvalvghtGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVlrqgVAMVQQD 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 80 PELtfnpwrsIADSL------------QDFWspdaEMMARLHIA------PEWLTRRPGQ----LSGGELARLALLRALD 137
Cdd:PRK10790 424 PVV-------LADTFlanvtlgrdiseEQVW----QALETVQLAelarslPDGLYTPLGEqgnnLSVGQKQLLALARVLV 492
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446870191 138 PRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALgmVVISHQ 181
Cdd:PRK10790 493 QTPQILILDEATANIDSGTEQAIQQALAAVREHTTL--VVIAHR 534
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
12-72 |
7.45e-07 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 48.35 E-value: 7.45e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKplANCGYCP 72
Cdd:PRK15064 330 DNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSEN--ANIGYYA 388
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
36-180 |
7.48e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 48.20 E-value: 7.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 36 SGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCP--------VQLVPQHPE-----------LTFNPwrsiadslQD 96
Cdd:PRK13649 42 TGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKdikqirkkVGLVFQFPEsqlfeetvlkdVAFGP--------QN 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 97 FW--SPDAEMMAR-----LHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQ 169
Cdd:PRK13649 114 FGvsQEEAEALAReklalVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQ 193
|
170
....*....|...
gi 446870191 170 rraLGM--VVISH 180
Cdd:PRK13649 194 ---SGMtiVLVTH 203
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
19-67 |
7.81e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 48.46 E-value: 7.81e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN 67
Cdd:PRK10762 270 DVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVT 318
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
1-67 |
9.64e-07 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 47.54 E-value: 9.64e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN 67
Cdd:PRK13543 11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATR 77
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
36-180 |
1.04e-06 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 47.36 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 36 SGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYcPVQLVPQHPELTfnPWRSIADS----LQDFWSPDA-EMMARLHI 110
Cdd:PRK11247 47 SGCGKSTLLRLLAGLETPSAGELLAGTAPLAEARE-DTRLMFQDARLL--PWKKVIDNvglgLKGQWRDAAlQALAAVGL 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446870191 111 ---APEWltrrPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK11247 124 adrANEW----PAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTH 192
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
18-187 |
1.17e-06 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 47.18 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQLVPQHPELTFNPW-----RSIAD 92
Cdd:PRK10908 19 QGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHhllmdRTVYD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 93 -----------SLQDFW---SPDAEMMARLHIAPEWltrrPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:PRK10908 99 nvaipliiagaSGDDIRrrvSAALDKVGLLDKAKNF----PIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALSE 174
|
170 180
....*....|....*....|....*....
gi 446870191 159 DVWTfLLELCQRRALGMVVISHQKALVAQ 187
Cdd:PRK10908 175 GILR-LFEEFNRVGVTVLMATHDIGLISR 202
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
14-67 |
1.25e-06 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 47.92 E-value: 1.25e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 446870191 14 KVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQkPLSGEVLVDGKPLAN 67
Cdd:PRK11174 363 KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRE 415
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
11-189 |
1.38e-06 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 47.20 E-value: 1.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK-----PLANCGYCPVQLVPQHPEL--- 82
Cdd:PRK10895 14 KGRRVV-EDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEdisllPLHARARRGIGYLPQEASIfrr 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 --TFNPWRSIADSLQDFWSPD-----AEMMARLHIAPewLTRRPGQ-LSGGELARLALLRALDPRTRFLIADEITAQLDP 154
Cdd:PRK10895 93 lsVYDNLMAVLQIRDDLSAEQredraNELMEEFHIEH--LRDSMGQsLSGGERRRVEIARALAANPKFILLDEPFAGVDP 170
|
170 180 190
....*....|....*....|....*....|....*
gi 446870191 155 ATQRDVWTfLLELCQRRALGMVVISHQKALVAQVC 189
Cdd:PRK10895 171 ISVIDIKR-IIEHLRDSGLGVLITDHNVRETLAVC 204
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
2-67 |
1.40e-06 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 46.75 E-value: 1.40e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQ--KPLSGEVLVDGKPLAN 67
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITD 68
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
5-62 |
1.56e-06 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 47.07 E-value: 1.56e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446870191 5 RDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG 62
Cdd:PRK11831 11 RGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDG 68
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1-182 |
1.61e-06 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 46.48 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAN--CGYcPVQLVPQ 78
Cdd:PRK13540 1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKdlCTY-QKQLCFV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 79 HPELTFNPWRSIADS-LQDFWSPDAEM----MARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLD 153
Cdd:PRK13540 80 GHRSGINPYLTLRENcLYDIHFSPGAVgiteLCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALD 159
|
170 180 190
....*....|....*....|....*....|.
gi 446870191 154 patQRDVWTFLLELCQRRALGMVVI--SHQK 182
Cdd:PRK13540 160 ---ELSLLTIITKIQEHRAKGGAVLltSHQD 187
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-180 |
1.93e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 47.00 E-value: 1.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIR------QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGycpvq 74
Cdd:PRK13633 4 MIKCKNVSYKyesneeSTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEE----- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 75 lvpqhpeltfNPW--RSIADSLqdFWSPDAEMMA------------RLHIAPEWLTRR-----------------PGQLS 123
Cdd:PRK13633 79 ----------NLWdiRNKAGMV--FQNPDNQIVAtiveedvafgpeNLGIPPEEIRERvdeslkkvgmyeyrrhaPHLLS 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446870191 124 GGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK13633 147 GGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITH 203
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
20-66 |
2.05e-06 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 47.27 E-value: 2.05e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA 66
Cdd:PRK10522 342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVT 388
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
20-65 |
2.06e-06 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 47.10 E-value: 2.06e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL 65
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPV 396
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
19-69 |
3.76e-06 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 46.20 E-value: 3.76e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG 69
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALS 331
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
2-65 |
4.75e-06 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 46.08 E-value: 4.75e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 2 LSCRDLLIRQGEKVlwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG-WQKPLSGEVLVDGKPL 65
Cdd:PRK13549 265 LTAWDPVNPHIKRV--DDVSFSLRRGEILGIAGLVGAGRTELVQCLFGaYPGRWEGEIFIDGKPV 327
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
21-153 |
5.67e-06 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 45.96 E-value: 5.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 21 SFSL-------RPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKplanCGYCPvQLVPQHPELTFNPW-RSIAD 92
Cdd:PRK13409 352 DFSLeveggeiYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK----ISYKP-QYIKPDYDGTVEDLlRSITD 426
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 93 SLQD--FWSpdaEMMARLHIaPEWLTRRPGQLSGGElarlallraldpRTRFLIA------------DEITAQLD 153
Cdd:PRK13409 427 DLGSsyYKS---EIIKPLQL-ERLLDKNVKDLSGGE------------LQRVAIAaclsrdadlyllDEPSAHLD 485
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1-65 |
6.84e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 45.07 E-value: 6.84e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446870191 1 MLSCRDLLIR--QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL 65
Cdd:PRK13639 1 ILETRDLKYSypDGTEAL-KGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPI 66
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
10-66 |
8.34e-06 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 44.79 E-value: 8.34e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA 66
Cdd:cd03244 13 RPNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDIS 69
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
19-180 |
8.48e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 45.13 E-value: 8.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPELTFNPwrSI---- 90
Cdd:PRK13648 27 DVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRkhigIVFQNPDNQFVG--SIvkyd 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 -ADSLQDFWSPDAEMMarlHIAPEWLTR---------RPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDV 160
Cdd:PRK13648 105 vAFGLENHAVPYDEMH---RRVSEALKQvdmleradyEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNL 181
|
170 180
....*....|....*....|
gi 446870191 161 WTFLLELCQRRALGMVVISH 180
Cdd:PRK13648 182 LDLVRKVKSEHNITIISITH 201
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-187 |
8.93e-06 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 44.82 E-value: 8.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG--------WQKPLSGEVLVDGKPLANCG--- 69
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdltgggapRGARVTGDVTLNGEPLAAIDapr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 70 -YCPVQLVPQHPELTF--------------NPWRSIADSLQDFWSPDAEMmaRLHIAPEWLTRRPGQLSGGELARLA--- 131
Cdd:PRK13547 81 lARLRAVLPQAAQPAFafsareivllgrypHARRAGALTHRDGEIAWQAL--ALAGATALVGRDVTTLSGGELARVQfar 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446870191 132 ------LLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQ 187
Cdd:PRK13547 159 vlaqlwPPHDAAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAAR 220
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
12-82 |
9.31e-06 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 45.11 E-value: 9.31e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDgkPLANCGYcpvqlVPQHPEL 82
Cdd:PRK11819 18 PKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPA--PGIKVGY-----LPQEPQL 81
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
18-193 |
1.04e-05 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 44.62 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG-------KPLANCGYC---PVQLVPQH----PELT 83
Cdd:COG4161 19 FDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGhqfdfsqKPSEKAIRLlrqKVGMVFQQynlwPHLT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 84 F------NPWRSIADSLQDFWSPDAEMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQ 157
Cdd:COG4161 99 VmenlieAPCKVLGLSKEQAREKAMKLLARLRLT-DKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEIT 177
|
170 180 190
....*....|....*....|....*....|....*.
gi 446870191 158 RDVWTFLLELCQrRALGMVVISHQKALVAQVCSSLL 193
Cdd:COG4161 178 AQVVEIIRELSQ-TGITQVIVTHEVEFARKVASQVV 212
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
1-65 |
1.05e-05 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 44.78 E-value: 1.05e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQ--KPLSGEVLVDGKPL 65
Cdd:PRK09580 1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDL 67
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
12-185 |
1.41e-05 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 44.33 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKplANCGYCP--VQLVPQHPE-----LTF 84
Cdd:PRK09544 15 GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGK--LRIGYVPqkLYLDTTLPLtvnrfLRL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 NPWRSIADSLqdfwspdaEMMARLHIAPewLTRRPGQ-LSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTF 163
Cdd:PRK09544 93 RPGTKKEDIL--------PALKRVQAGH--LIDAPMQkLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDL 162
|
170 180
....*....|....*....|..
gi 446870191 164 LLELCQRRALGMVVISHQKALV 185
Cdd:PRK09544 163 IDQLRRELDCAVLMVSHDLHLV 184
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
12-185 |
1.45e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 44.78 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEV-LVDGKPLancGYcpvqlVPQHpELTFnpWRSI 90
Cdd:PRK10636 323 GDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIgLAKGIKL---GY-----FAQH-QLEF--LRAD 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 91 ADSLQDfwspdaemMARLhiAPEWL------------------TRRPGQLSGGELARLALLRALDPRTRFLIADEITAQL 152
Cdd:PRK10636 392 ESPLQH--------LARL--APQELeqklrdylggfgfqgdkvTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHL 461
|
170 180 190
....*....|....*....|....*....|...
gi 446870191 153 DpatqrdvwtflleLCQRRALGMVVISHQKALV 185
Cdd:PRK10636 462 D-------------LDMRQALTEALIDFEGALV 481
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-193 |
1.59e-05 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 44.19 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA----NCGYCPV---- 73
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdKDGQLKVadkn 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 74 QLVPQHPELT-----FNPWRSIADSLQDFWSP---------DAEMMARLHIAPEWLTRR-----PGQLSGGELARLALLR 134
Cdd:PRK10619 86 QLRLLRTRLTmvfqhFNLWSHMTVLENVMEAPiqvlglskqEARERAVKYLAKVGIDERaqgkyPVHLSGGQQQRVSIAR 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446870191 135 ALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQrRALGMVVISHQKALVAQVCSSLL 193
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAE-EGKTMVVVTHEMGFARHVSSHVI 223
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
35-188 |
1.94e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 43.68 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 35 PSGSGKTTLGRVL-----AGWQKPLSGEVLVDGKPLANCGYCPVQ------LVPQHP----ELTFNPWRSIADSLQDFWS 99
Cdd:PRK14267 38 PSGCGKSTLLRTFnrlleLNEEARVEGEVRLFGRNIYSPDVDPIEvrrevgMVFQYPnpfpHLTIYDNVAIGVKLNGLVK 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 100 PDAEMMAR----LHIAPEW------LTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELcq 169
Cdd:PRK14267 118 SKKELDERvewaLKKAALWdevkdrLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFEL-- 195
|
170
....*....|....*....
gi 446870191 170 RRALGMVVISHQKALVAQV 188
Cdd:PRK14267 196 KKEYTIVLVTHSPAQAARV 214
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
7-194 |
2.44e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 44.20 E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 7 LLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQ----LVPQHPEL 82
Cdd:PLN03232 1242 LRYRPGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRrvlsIIPQSPVL 1321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 -----TFN--PWRSIADSlqDFWspdaEMMARLHIApEWLTRRPGQL-----------SGGELARLALLRALDPRTRFLI 144
Cdd:PLN03232 1322 fsgtvRFNidPFSEHNDA--DLW----EALERAHIK-DVIDRNPFGLdaevseggenfSVGQRQLLSLARALLRRSKILV 1394
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446870191 145 ADEITAQLDPATQRDVWTFLLElcQRRALGMVVISHQKALVAQvCSSLLV 194
Cdd:PLN03232 1395 LDEATASVDVRTDSLIQRTIRE--EFKSCTMLVIAHRLNTIID-CDKILV 1441
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-63 |
2.66e-05 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 43.48 E-value: 2.66e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQ--KPLSGEVLVDGK 63
Cdd:CHL00131 7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGE 71
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
11-188 |
3.60e-05 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 43.20 E-value: 3.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSG-----EVLVDGKPLANCGYCPVQLVPQHPELTFN 85
Cdd:PRK11264 14 HGQTVL-HGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGtirvgDITIDTARSLSQQKGLIRQLRQHVGFVFQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 86 -----PWRSIADSLQDfwSP---------DAEMMARLHIAPEWLTRR----PGQLSGGELARLALLRALDPRTRFLIADE 147
Cdd:PRK11264 93 nfnlfPHRTVLENIIE--GPvivkgepkeEATARARELLAKVGLAGKetsyPRRLSGGQQQRVAIARALAMRPEVILFDE 170
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446870191 148 ITAQLDPATQRDVWTFLLELCQRRALgMVVISHQKALVAQV 188
Cdd:PRK11264 171 PTSALDPELVGEVLNTIRQLAQEKRT-MVIVTHEMSFARDV 210
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
32-188 |
3.91e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 43.16 E-value: 3.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 32 LSTPSGSGKTTLGRVL-------AGWQkpLSGEVLVDGKPLANcgYCPVQLVPQHPELTF---NPW-RSIADSL-----Q 95
Cdd:PRK14271 52 LMGPTGSGKTTFLRTLnrmndkvSGYR--YSGDVLLGGRSIFN--YRDVLEFRRRVGMLFqrpNPFpMSIMDNVlagvrA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 96 DFWSPDAEM----MARLHIAPEW------LTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLL 165
Cdd:PRK14271 128 HKLVPRKEFrgvaQARLTEVGLWdavkdrLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIR 207
|
170 180
....*....|....*....|...
gi 446870191 166 ELCQRraLGMVVISHQKALVAQV 188
Cdd:PRK14271 208 SLADR--LTVIIVTHNLAQAARI 228
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
21-66 |
4.25e-05 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 43.36 E-value: 4.25e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446870191 21 SFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLA 66
Cdd:PRK11288 273 SFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPID 318
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
13-188 |
4.80e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 42.73 E-value: 4.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 13 EKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL----------ANCGYCPVQLVPQHPel 82
Cdd:PRK14246 22 DKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyfgkdifqidAIKLRKEVGMVFQQP-- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 tfNP------WRSIADSLQDFWSPDAEMMAR-----LHIAPEW------LTRRPGQLSGGELARLALLRALDPRTRFLIA 145
Cdd:PRK14246 100 --NPfphlsiYDNIAYPLKSHGIKEKREIKKiveecLRKVGLWkevydrLNSPASQLSGGQQQRLTIARALALKPKVLLM 177
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446870191 146 DEITAQLDPATQRDVWTFLLELcqRRALGMVVISHQKALVAQV 188
Cdd:PRK14246 178 DEPTSMIDIVNSQAIEKLITEL--KNEIAIVIVSHNPQQVARV 218
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
36-194 |
5.22e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 42.69 E-value: 5.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 36 SGSGKTTLGRVLAGWQKPLSGEVLV-DGKPLANCGYCP--------VQLVPQHPE-----------LTFNPWRSIADSlQ 95
Cdd:PRK13645 46 TGSGKSTMIQLTNGLIISETGQTIVgDYAIPANLKKIKevkrlrkeIGLVFQFPEyqlfqetiekdIAFGPVNLGENK-Q 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 96 DFWSPDAEMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGM 175
Cdd:PRK13645 125 EAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRI 204
|
170
....*....|....*....
gi 446870191 176 VVISHQKALVAQVCSSLLV 194
Cdd:PRK13645 205 IMVTHNMDQVLRIADEVIV 223
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
7-180 |
6.86e-05 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 42.28 E-value: 6.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 7 LLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKP---------------LANCGYC 71
Cdd:PRK10253 13 LTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHiqhyaskevarriglLAQNATT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 72 P----VQ-LV-----PQHPelTFNPWRsiadslqdfwSPDAEMMARLHIAPEwLTRRPGQ----LSGGELARLALLRALD 137
Cdd:PRK10253 93 PgditVQeLVargryPHQP--LFTRWR----------KEDEEAVTKAMQATG-ITHLADQsvdtLSGGQRQRAWIAMVLA 159
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446870191 138 PRTRFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK10253 160 QETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLH 202
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
12-62 |
1.05e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 42.20 E-value: 1.05e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446870191 12 GEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLgrvLAGWQKPLS--GEVLVDG 62
Cdd:TIGR01271 1231 GRAVL-QDLSFSVEGGQRVGLLGRTGSGKSTL---LSALLRLLSteGEIQIDG 1279
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
14-63 |
1.09e-04 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 41.99 E-value: 1.09e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 446870191 14 KVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK 63
Cdd:PRK10851 16 QVL-NDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGT 64
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
5-65 |
1.40e-04 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 41.69 E-value: 1.40e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 5 RDLLIRQGEKVlwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL 65
Cdd:PRK09700 269 RNVTSRDRKKV--RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDI 327
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
2-156 |
1.49e-04 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 41.38 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIR--QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLgrvLAGWQKPLS--GEVLVDGkplANCGYCPVQ--- 74
Cdd:cd03289 3 MTVKDLTAKytEGGNAVLENISFSISPGQRVGLLGRTGSGKSTL---LSAFLRLLNteGDIQIDG---VSWNSVPLQkwr 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 75 ----LVPQHPELTFNPWRSIAD-----SLQDFWSPDAEMMARLHIapewlTRRPGQ-----------LSGGELARLALLR 134
Cdd:cd03289 77 kafgVIPQKVFIFSGTFRKNLDpygkwSDEEIWKVAEEVGLKSVI-----EQFPGQldfvlvdggcvLSHGHKQLMCLAR 151
|
170 180
....*....|....*....|..
gi 446870191 135 ALDPRTRFLIADEITAQLDPAT 156
Cdd:cd03289 152 SVLSKAKILLLDEPSAHLDPIT 173
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
10-194 |
1.55e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 41.26 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPL--ANCGYC--PVQLVPQHPE---L 82
Cdd:PRK13647 15 KDGTKAL-KGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVnaENEKWVrsKVGLVFQDPDdqvF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 TFNPWRSIADSLQDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPAT 156
Cdd:PRK13647 94 SSTVWDDVAFGPVNMGLDKDEVERRVEEAlkavrmWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRG 173
|
170 180 190
....*....|....*....|....*....|....*...
gi 446870191 157 QRDVWTFLLELcQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK13647 174 QETLMEILDRL-HNQGKTVIVATHDVDLAAEWADQVIV 210
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
19-180 |
1.70e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 41.26 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLV------------DGKPLANcgycPVQLVPQHPE----- 81
Cdd:PRK13643 24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVgdivvsstskqkEIKPVRK----KVGVVFQFPEsqlfe 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 82 ------LTFNPwRSIADSLQDFWSPDAEMMARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPA 155
Cdd:PRK13643 100 etvlkdVAFGP-QNFGIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPK 178
|
170 180
....*....|....*....|....*
gi 446870191 156 TQRDVWTfLLELCQRRALGMVVISH 180
Cdd:PRK13643 179 ARIEMMQ-LFESIHQSGQTVVLVTH 202
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1-61 |
3.09e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 40.65 E-value: 3.09e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVD 61
Cdd:PRK15064 1 MLSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLD 61
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
10-156 |
3.36e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 40.70 E-value: 3.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGY----CPVQLVPQHPEL--- 82
Cdd:TIGR00957 1295 REDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLhdlrFKITIIPQDPVLfsg 1374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 83 ----TFNPWRSIADslQDFWSpdAEMMARLH----IAPEWLTRRPGQ----LSGGELARLALLRALDPRTRFLIADEITA 150
Cdd:TIGR00957 1375 slrmNLDPFSQYSD--EEVWW--ALELAHLKtfvsALPDKLDHECAEggenLSVGQRQLVCLARALLRKTKILVLDEATA 1450
|
....*.
gi 446870191 151 QLDPAT 156
Cdd:TIGR00957 1451 AVDLET 1456
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
19-193 |
3.37e-04 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 40.00 E-value: 3.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 19 NLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG-------KPLANCGYC---PVQLVPQH----PELTF 84
Cdd:PRK11124 20 DITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhfdfskTPSDKAIRElrrNVGMVFQQynlwPHLTV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 ------NPWRSIADSLQDFWSPDAEMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQR 158
Cdd:PRK11124 100 qqnlieAPCRVLGLSKDQALARAEKLLERLRLK-PYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITA 178
|
170 180 190
....*....|....*....|....*....|....*
gi 446870191 159 DVWTFLLELcQRRALGMVVISHQKALVAQVCSSLL 193
Cdd:PRK11124 179 QIVSIIREL-AETGITQVIVTHEVEVARKTASRVV 212
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
12-58 |
3.48e-04 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 40.70 E-value: 3.48e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEV 58
Cdd:PRK11147 330 DGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI 376
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
18-63 |
3.80e-04 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 40.54 E-value: 3.80e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK 63
Cdd:PRK09700 22 KSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNI 67
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-92 |
3.89e-04 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 40.02 E-value: 3.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVL-------AGwQKpLSGEVLVDGKPLANCGYCPVQ 74
Cdd:COG1117 12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmndliPG-AR-VEGEILLDGEDIYDPDVDVVE 89
|
90 100
....*....|....*....|....*
gi 446870191 75 L------VPQHPeltfNPW-RSIAD 92
Cdd:COG1117 90 LrrrvgmVFQKP----NPFpKSIYD 110
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
18-180 |
3.89e-04 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 40.39 E-value: 3.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG--------KPLANcgycPVQLVPQHPELtFNPW-- 87
Cdd:PRK11176 360 RNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGhdlrdytlASLRN----QVALVSQNVHL-FNDTia 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 88 RSIADSLQDFWS-PDAEMMARLHIAPEWLTRRP-------GQ----LSGGElarlallraldpRTRFLIA---------- 145
Cdd:PRK11176 435 NNIAYARTEQYSrEQIEEAARMAYAMDFINKMDngldtviGEngvlLSGGQ------------RQRIAIArallrdspil 502
|
170 180 190
....*....|....*....|....*....|....*..
gi 446870191 146 --DEITAQLDPATQRDVWTFLLELCQRRAlgMVVISH 180
Cdd:PRK11176 503 ilDEATSALDTESERAIQAALDELQKNRT--SLVIAH 537
|
|
| cyc_pep_trnsptr |
TIGR01194 |
cyclic peptide transporter; This model describes cyclic peptide transporter in bacteria. ... |
20-180 |
4.45e-04 |
|
cyclic peptide transporter; This model describes cyclic peptide transporter in bacteria. Bacteria have elaborate pathways for the production of toxins and secondary metabolites. Many such compounds, including syringomycin and pyoverdine are synthesized on non-ribosomal templates consisting of a multienzyme complex. On several occasions the proteins of the complex and transporter protein are present on the same operon. Often times these compounds cross the biological membrane by specific transporters. Syringomycin is an amphipathic, cylclic lipodepsipeptide when inserted into host causes formation of channels, permeable to variety of cations. On the other hand, pyoverdine is a cyclic octa-peptidyl dihydroxyquinoline, which is efficient in sequestering iron for uptake. [Transport and binding proteins, Amino acids, peptides and amines, Transport and binding proteins, Other]
Pssm-ID: 130262 [Multi-domain] Cd Length: 555 Bit Score: 40.33 E-value: 4.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLAncgycpvqlvpqhpELTFNPWRSIADSL----- 94
Cdd:TIGR01194 361 IDLRIAQGDIVFIVGENGCGKSTLAKLFCGLYIPQEGEILLDGAAVS--------------ADSRDDYRDLFSAIfadfh 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 95 --QDFWSPDAEMMARLHIAPEWLTR---------------RPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQ 157
Cdd:TIGR01194 427 lfDDLIGPDEGEHASLDNAQQYLQRleiadkvkiedggfsTTTALSTGQQKRLALICAWLEDRPILLFDEWAADQDPAFK 506
|
170 180
....*....|....*....|...
gi 446870191 158 RDVWTFLLELCQRRALGMVVISH 180
Cdd:TIGR01194 507 RFFYEELLPDLKRQGKTIIIISH 529
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
11-89 |
5.07e-04 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 40.08 E-value: 5.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 11 QGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLgrvLAGWQKPL---SGEVLVDGKPLancgycpvqlvpqhPELTFNPW 87
Cdd:PRK10789 325 QTDHPALENVNFTLKPGQMLGICGPTGSGKSTL---LSLIQRHFdvsEGDIRFHDIPL--------------TKLQLDSW 387
|
..
gi 446870191 88 RS 89
Cdd:PRK10789 388 RS 389
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
13-180 |
6.00e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 39.40 E-value: 6.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 13 EKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGE---VLVDGKPLANCGYCPVQ----LVPQHPELTF- 84
Cdd:PRK13640 19 KKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTAKTVWDIRekvgIVFQNPDNQFv 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 85 --NPWRSIADSLQDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPAT 156
Cdd:PRK13640 99 gaTVGDDVAFGLENRAVPRPEMIKIVRDVladvgmLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAG 178
|
170 180
....*....|....*....|....
gi 446870191 157 QRDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK13640 179 KEQILKLIRKLKKKNNLTVISITH 202
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
23-58 |
8.07e-04 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 39.38 E-value: 8.07e-04
10 20 30
....*....|....*....|....*....|....*.
gi 446870191 23 SLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEV 58
Cdd:COG1245 362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV 397
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
4-74 |
8.60e-04 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 39.71 E-value: 8.60e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446870191 4 CRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKP---LSGEVLVDGKPLANC-----GYCPVQ 74
Cdd:TIGR00956 766 TYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLDSSfqrsiGYVQQQ 844
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
35-188 |
9.39e-04 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 38.86 E-value: 9.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 35 PSGSGKTTLGRVLAGWQKpLSGEVLVDGK--------------------------------PLA---NCGYcPVQLVPQH 79
Cdd:PRK14258 41 PSGCGKSTFLKCLNRMNE-LESEVRVEGRveffnqniyerrvnlnrlrrqvsmvhpkpnlfPMSvydNVAY-GVKIVGWR 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 80 PELTFNPWRSIADSLQDFWSpdaEMMARLHiapewltRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRD 159
Cdd:PRK14258 119 PKLEIDDIVESALKDADLWD---EIKHKIH-------KSALDLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMK 188
|
170 180
....*....|....*....|....*....
gi 446870191 160 VWTFLLELCQRRALGMVVISHQKALVAQV 188
Cdd:PRK14258 189 VESLIQSLRLRSELTMVIVSHNLHQVSRL 217
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
20-193 |
1.36e-03 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 38.46 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGW----QKP------LSGEVLVDG-------KPLANCGYCPVQ--LVPQHP 80
Cdd:PRK09984 23 VDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgdKSAgshielLGRTVQREGrlardirKSRANTGYIFQQfnLVNRLS 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 --------ELTFNP-WRSIADSLQDFWSPDA-EMMARLHIApEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITA 150
Cdd:PRK09984 103 vlenvligALGSTPfWRTCFSWFTREQKQRAlQALTRVGMV-HFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIA 181
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446870191 151 QLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLL 193
Cdd:PRK09984 182 SLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIV 224
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
13-187 |
1.72e-03 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 38.22 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 13 EKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG------------KPLANcgycPVQLVPQHP 80
Cdd:PRK13646 19 EHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDitithktkdkyiRPVRK----RIGMVFQFP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 ELTF---NPWRSIADSLQDFWSPDAEMMARLH-------IAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITA 150
Cdd:PRK13646 95 ESQLfedTVEREIIFGPKNFKMNLDEVKNYAHrllmdlgFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174
|
170 180 190
....*....|....*....|....*....|....*..
gi 446870191 151 QLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQ 187
Cdd:PRK13646 175 GLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVAR 211
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
10-83 |
1.82e-03 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 37.63 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 10 RQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKP---LSGEVLVDGKPLA-NCGYCPVQL--VPQH---- 79
Cdd:cd03233 16 GRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGnvsVEGDIHYNGIPYKeFAEKYPGEIiyVSEEdvhf 95
|
....
gi 446870191 80 PELT 83
Cdd:cd03233 96 PTLT 99
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
12-63 |
2.03e-03 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 38.30 E-value: 2.03e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK 63
Cdd:PLN03073 520 GGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAK 571
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
1-71 |
2.40e-03 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 37.54 E-value: 2.40e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446870191 1 MLSCRDLLIRQGEKVLWqNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCG--YC 71
Cdd:PRK13541 1 MLSLHQLQFNIEQKNLF-DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAkpYC 72
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
141-194 |
2.78e-03 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 37.58 E-value: 2.78e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 446870191 141 RFLIADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:COG4170 178 RLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITV 231
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
2-180 |
2.94e-03 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 37.71 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 2 LSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKPLANCGYCPVQLVPQHP- 80
Cdd:PRK10070 29 LSKEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKi 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 81 -----ELTFNPWRSIADS----LQDFWSPDAEMMARLHIA------PEWLTRRPGQLSGGELARLALLRALDPRTRFLIA 145
Cdd:PRK10070 109 amvfqSFALMPHMTVLDNtafgMELAGINAEERREKALDAlrqvglENYAHSYPDELSGGMRQRVGLARALAINPDILLM 188
|
170 180 190
....*....|....*....|....*....|....*
gi 446870191 146 DEITAQLDPATQRDVWTFLLELCQRRALGMVVISH 180
Cdd:PRK10070 189 DEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISH 223
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
12-126 |
3.78e-03 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 37.32 E-value: 3.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 12 GEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGK-----PLANCGycpVQLVPQHPELTfnP 86
Cdd:PRK11000 14 GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKrmndvPPAERG---VGMVFQSYALY--P 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 446870191 87 WRSIADS----LQDFWSPDAEMMARLHIAPE------WLTRRPGQLSGGE 126
Cdd:PRK11000 89 HLSVAENmsfgLKLAGAKKEEINQRVNQVAEvlqlahLLDRKPKALSGGQ 138
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1-49 |
3.81e-03 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 37.46 E-value: 3.81e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446870191 1 MLSCRDLLIRQGEKVLWQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG 49
Cdd:PRK10636 1 MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKN 49
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
26-180 |
4.46e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 36.20 E-value: 4.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 26 PGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVdgkplANCgycpvqlvpqhpeltfnpwrsiadslqdfwsPDAEMM 105
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----IDG-------------------------------EDILEE 44
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 106 ARLHIAPEWLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVW-----TFLLELCQRRALGMVVISH 180
Cdd:smart00382 45 VLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleelRLLLLLKSEKNLTVILTTN 124
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
18-72 |
4.58e-03 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 36.68 E-value: 4.58e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 446870191 18 QNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDGKplanCGYCP 72
Cdd:cd03250 22 KDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS----IAYVS 72
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
114-194 |
4.61e-03 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 37.14 E-value: 4.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 114 WLTRRPGQLSGGELARLALLRALDPRTRFLIADEITAQLDPATQRDVWTFLLElCQRRALGMVVISHQKALVAQVCSSLL 193
Cdd:PRK13631 169 YLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVADEVI 247
|
.
gi 446870191 194 V 194
Cdd:PRK13631 248 V 248
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
20-194 |
4.74e-03 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 37.09 E-value: 4.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 20 LSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPlSGEVLVDGKPLANCGYCP-------------VQLVPQHPELTFNP 86
Cdd:PRK15093 26 VSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKD-NWRVTADRMRFDDIDLLRlsprerrklvghnVSMIFQEPQSCLDP 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446870191 87 WRSIADSLQDF---WSPDAEMMARLHiapeWLTRR--------------------PGQLSGGELARLALLRALDPRTRFL 143
Cdd:PRK15093 105 SERVGRQLMQNipgWTYKGRWWQRFG----WRKRRaiellhrvgikdhkdamrsfPYELTEGECQKVMIAIALANQPRLL 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446870191 144 IADEITAQLDPATQRDVWTFLLELCQRRALGMVVISHQKALVAQVCSSLLV 194
Cdd:PRK15093 181 IADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINV 231
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
5-62 |
5.15e-03 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 37.18 E-value: 5.15e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446870191 5 RDLLIRQGEKVL---WQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAGWQKPLSGEVLVDG 62
Cdd:PRK13545 25 KDLFFRSKDGEYhyaLNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG 85
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
9-65 |
6.09e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 36.69 E-value: 6.09e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446870191 9 IRQGEKVLwQNLSFSLRPGERLGLSTPSGSGKTTLGRVLAG--WQKPLSGEVLVDGKPL 65
Cdd:NF040905 269 LHPERKVV-DDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEV 326
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
21-53 |
7.22e-03 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 36.19 E-value: 7.22e-03
10 20 30
....*....|....*....|....*....|....*....
gi 446870191 21 SFSL------RPGERLGLSTPSGSGKTTLGRVLAGWQKP 53
Cdd:cd03236 14 SFKLhrlpvpREGQVLGLVGPNGIGKSTALKILAGKLKP 52
|
|
| |
