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Conserved domains on  [gi|489055905|ref|WP_002966050|]
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MULTISPECIES: cytochrome c biogenesis CcdA family protein [Brucella]

Protein Classification

cytochrome c biogenesis CcdA family protein( domain architecture ID 10002692)

cytochrome c biogenesis CcdA family protein, such as cytochrome c biogenesis protein CcdA, which is a thiol disulfide transporter that plays a role in the maturation of cytochrome c

Gene Ontology:  GO:0016020|GO:0017004
PubMed:  26389738
TCDB:  5.A.1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CcdA COG0785
Cytochrome c biogenesis protein CcdA [Energy production and conversion, Posttranslational ...
2-209 4.15e-55

Cytochrome c biogenesis protein CcdA [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440548 [Multi-domain]  Cd Length: 193  Bit Score: 175.42  E-value: 4.15e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   2 LDISYMTAAGAGALSFLSPCVLPLVPPYLCYMAGVSvedfradaskatakPSARRSLGFAALCFVLGFTTVFVALGAGAS 81
Cdd:COG0785    1 MLLSLLLAFLAGLLSFLSPCVLPLLPGYLSYLTGLS--------------RASRRRALLRALLFVLGFSLVFVLLGALAS 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905  82 SIGAFLRTWQQQIAIVAGVVIILMGLNFLGLLRLSFLSREARFQARNaPASPLGAYIMGLAFAFGWTPCIGPVLGPILTL 161
Cdd:COG0785   67 ALGSLLGQYQDLLRIVAGVLLILFGLVLLGLLKIPFLQREARINLRR-KAGLLGAFLLGLAFGLGWTPCIGPILGAILAL 145
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489055905 162 AGGSSTVGEGALLLATYSLGLGIPFLIAALFSGAFMRFLSRFRVHLGK 209
Cdd:COG0785  146 AATSGSVLRGALLLLAYALGLGLPFLLLALFAGRLLGRLRRLRRHLRW 193
 
Name Accession Description Interval E-value
CcdA COG0785
Cytochrome c biogenesis protein CcdA [Energy production and conversion, Posttranslational ...
2-209 4.15e-55

Cytochrome c biogenesis protein CcdA [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440548 [Multi-domain]  Cd Length: 193  Bit Score: 175.42  E-value: 4.15e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   2 LDISYMTAAGAGALSFLSPCVLPLVPPYLCYMAGVSvedfradaskatakPSARRSLGFAALCFVLGFTTVFVALGAGAS 81
Cdd:COG0785    1 MLLSLLLAFLAGLLSFLSPCVLPLLPGYLSYLTGLS--------------RASRRRALLRALLFVLGFSLVFVLLGALAS 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905  82 SIGAFLRTWQQQIAIVAGVVIILMGLNFLGLLRLSFLSREARFQARNaPASPLGAYIMGLAFAFGWTPCIGPVLGPILTL 161
Cdd:COG0785   67 ALGSLLGQYQDLLRIVAGVLLILFGLVLLGLLKIPFLQREARINLRR-KAGLLGAFLLGLAFGLGWTPCIGPILGAILAL 145
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489055905 162 AGGSSTVGEGALLLATYSLGLGIPFLIAALFSGAFMRFLSRFRVHLGK 209
Cdd:COG0785  146 AATSGSVLRGALLLLAYALGLGLPFLLLALFAGRLLGRLRRLRRHLRW 193
DsbD pfam02683
Cytochrome C biogenesis protein transmembrane region; This family consists of the ...
11-227 1.10e-47

Cytochrome C biogenesis protein transmembrane region; This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins. These proteins posses a protein disulphide isomerase like domain that is not found within the aligned region of this family.


Pssm-ID: 280792 [Multi-domain]  Cd Length: 213  Bit Score: 156.79  E-value: 1.10e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   11 GAGALSFLSPCVLPLVPPYLCYMAGVSVEDFRADAskatakpsARRSLGFAALCFVLGFTTVFVALGAGASSIGAFLRTW 90
Cdd:pfam02683   3 LAGLLSFLSPCILPLIPAYLSYISGVSVGDRKQGK--------KRVRVLLKSLLFVLGLSLVFVLLGLSAAFLGQLFGDF 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   91 QQQIAIVAGVVIILMGLNFLGLLRLSFLSREAR--FQARNAPASPLGAYIMGLAFAFGWTPCIGPVLGPILTLAGGSSTV 168
Cdd:pfam02683  75 KGWVRIIAGLIVILFGLHFLGVFRIPFLYKLRLvhKTKKKISLPVLGAFLLGMTFALGWTPCIGPILASVLALAASTGSL 154
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 489055905  169 GEGALLLATYSLGLGIPFLIAALFSGAFMRFLSRFRVHLGKVEKAMGVLLIIAGVVFLT 227
Cdd:pfam02683 155 LLGAGLMVVYVLGLAAPFLLASLFFGSLLLRLKWLRKNSHWVKIAGGVLLILFGVLLLL 213
dipZ PRK00293
thiol:disulfide interchange protein precursor; Provisional
9-227 3.56e-05

thiol:disulfide interchange protein precursor; Provisional


Pssm-ID: 234717 [Multi-domain]  Cd Length: 571  Bit Score: 44.43  E-value: 3.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   9 AAGAGaLSFlSPCVLPLVPpylcYMAGVSVEDFRadaskataKPSARRSLGFAaLCFVLGFTTVFVALGAGASSIGAFLR 88
Cdd:PRK00293 174 LIGIG-LAF-TPCVLPMYP----ILSGIVLGGKQ--------RLSTARALLLS-FVYVQGMALTYTLLGLVVAAAGLQFQ 238
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905  89 TWQQQ--IAIVAGVVIILMGLNFLGL--LRL--SFLSREARFQARNAPASPLGAYIMGLAFAFGWTPCIGPVLGPILTLA 162
Cdd:PRK00293 239 AALQHpyVLIGLSILFVLLALSMFGLftLQLpsSLQTRLTLLSNRQQGGSLGGVFVMGAISGLICSPCTTAPLSGALLYI 318
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489055905 163 GGSSTVGEGALLLATYSLGLGIPFLIAALFSGafmRFLSRFRVHLGKVEKAMGVLLIIAGVVFLT 227
Cdd:PRK00293 319 AQSGDLLLGGLTLYLLALGMGLPLILITTFGN---KLLPKSGPWMNQVKTAFGFVLLALPVFLLE 380
 
Name Accession Description Interval E-value
CcdA COG0785
Cytochrome c biogenesis protein CcdA [Energy production and conversion, Posttranslational ...
2-209 4.15e-55

Cytochrome c biogenesis protein CcdA [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440548 [Multi-domain]  Cd Length: 193  Bit Score: 175.42  E-value: 4.15e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   2 LDISYMTAAGAGALSFLSPCVLPLVPPYLCYMAGVSvedfradaskatakPSARRSLGFAALCFVLGFTTVFVALGAGAS 81
Cdd:COG0785    1 MLLSLLLAFLAGLLSFLSPCVLPLLPGYLSYLTGLS--------------RASRRRALLRALLFVLGFSLVFVLLGALAS 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905  82 SIGAFLRTWQQQIAIVAGVVIILMGLNFLGLLRLSFLSREARFQARNaPASPLGAYIMGLAFAFGWTPCIGPVLGPILTL 161
Cdd:COG0785   67 ALGSLLGQYQDLLRIVAGVLLILFGLVLLGLLKIPFLQREARINLRR-KAGLLGAFLLGLAFGLGWTPCIGPILGAILAL 145
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489055905 162 AGGSSTVGEGALLLATYSLGLGIPFLIAALFSGAFMRFLSRFRVHLGK 209
Cdd:COG0785  146 AATSGSVLRGALLLLAYALGLGLPFLLLALFAGRLLGRLRRLRRHLRW 193
DsbD pfam02683
Cytochrome C biogenesis protein transmembrane region; This family consists of the ...
11-227 1.10e-47

Cytochrome C biogenesis protein transmembrane region; This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins. These proteins posses a protein disulphide isomerase like domain that is not found within the aligned region of this family.


Pssm-ID: 280792 [Multi-domain]  Cd Length: 213  Bit Score: 156.79  E-value: 1.10e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   11 GAGALSFLSPCVLPLVPPYLCYMAGVSVEDFRADAskatakpsARRSLGFAALCFVLGFTTVFVALGAGASSIGAFLRTW 90
Cdd:pfam02683   3 LAGLLSFLSPCILPLIPAYLSYISGVSVGDRKQGK--------KRVRVLLKSLLFVLGLSLVFVLLGLSAAFLGQLFGDF 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   91 QQQIAIVAGVVIILMGLNFLGLLRLSFLSREAR--FQARNAPASPLGAYIMGLAFAFGWTPCIGPVLGPILTLAGGSSTV 168
Cdd:pfam02683  75 KGWVRIIAGLIVILFGLHFLGVFRIPFLYKLRLvhKTKKKISLPVLGAFLLGMTFALGWTPCIGPILASVLALAASTGSL 154
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 489055905  169 GEGALLLATYSLGLGIPFLIAALFSGAFMRFLSRFRVHLGKVEKAMGVLLIIAGVVFLT 227
Cdd:pfam02683 155 LLGAGLMVVYVLGLAAPFLLASLFFGSLLLRLKWLRKNSHWVKIAGGVLLILFGVLLLL 213
DsbD COG4232
Thiol:disulfide interchange protein DsbD [Posttranslational modification, protein turnover, ...
9-227 1.33e-15

Thiol:disulfide interchange protein DsbD [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443376 [Multi-domain]  Cd Length: 416  Bit Score: 75.23  E-value: 1.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   9 AAGAGALSFLSPCVLPLVPPYLCYMAGVSVEDfradaskatakpsaRRSLGFAALCFVLGFTTVFVALGAGASSIG--AF 86
Cdd:COG4232    9 AFLGGLLLNLTPCVLPMLPIKSSIIVGQGGKS--------------RRRAFLLSLAYVLGMALTYTLLGLLAALLGgaVG 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905  87 LRTWQQQIAIVAG--VVIILMGLNFLGLLRLSFLSR-EARFQARNAPASPLGAYIMGLAFAFGWTPCIGPVLGPILTLAG 163
Cdd:COG4232   75 WGFQLQSPWVLGAlaLLFVLLALSMFGLFELQLPSSlQNRLAALSNGGGLLGAFFMGVLAALVATPCTAPFLGGALGYAL 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489055905 164 GSSTVGEGALLLATYSLGLGIPFLIAALFsGAFMRFLSRFRVHLGKVEKAMGVLLIIAGVVFLT 227
Cdd:COG4232  155 QTGDALLGLLALFALGLGMALPLLLLGLF-PGLLKLLPKPGAWMETVKQVFGFLLLATAIWLLS 217
DsbD_2 pfam13386
Cytochrome C biogenesis protein transmembrane region;
48-224 1.80e-07

Cytochrome C biogenesis protein transmembrane region;


Pssm-ID: 463866  Cd Length: 199  Bit Score: 49.92  E-value: 1.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   48 ATAKPSARRSLGFAALCFVLGFTTVFVALGAGASSIGAFLRTWQQQ------IAIVAGVVIILMGLNFLGLLRLSFLSRE 121
Cdd:pfam13386  21 VLALSLALPSRRFALLLYNLGRILSYTLLGALAGLLGSVLSLAGQLaglrgvLGVLLGLLLLLLGLYLLGLPGLLKLERL 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905  122 ARFQAR------NAPASPLGAYIMGlaFAFGWTPCiGPVLgPILTLAGGSSTVGEGALLLATYSLGLGIPFLIAALFSGA 195
Cdd:pfam13386 101 GKGLWRllsplaKRLKSPGGAFLLG--LLWGLLPC-GLVY-SALLYAAATGSALEGALVMLAFGLGTLPALLLFGLLAGF 176
                         170       180
                  ....*....|....*....|....*....
gi 489055905  196 FMRFLSRfrvhlgKVEKAMGVLLIIAGVV 224
Cdd:pfam13386 177 LSKKLRK------RLQRLAGVLLILLGIL 199
dipZ PRK00293
thiol:disulfide interchange protein precursor; Provisional
9-227 3.56e-05

thiol:disulfide interchange protein precursor; Provisional


Pssm-ID: 234717 [Multi-domain]  Cd Length: 571  Bit Score: 44.43  E-value: 3.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905   9 AAGAGaLSFlSPCVLPLVPpylcYMAGVSVEDFRadaskataKPSARRSLGFAaLCFVLGFTTVFVALGAGASSIGAFLR 88
Cdd:PRK00293 174 LIGIG-LAF-TPCVLPMYP----ILSGIVLGGKQ--------RLSTARALLLS-FVYVQGMALTYTLLGLVVAAAGLQFQ 238
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489055905  89 TWQQQ--IAIVAGVVIILMGLNFLGL--LRL--SFLSREARFQARNAPASPLGAYIMGLAFAFGWTPCIGPVLGPILTLA 162
Cdd:PRK00293 239 AALQHpyVLIGLSILFVLLALSMFGLftLQLpsSLQTRLTLLSNRQQGGSLGGVFVMGAISGLICSPCTTAPLSGALLYI 318
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489055905 163 GGSSTVGEGALLLATYSLGLGIPFLIAALFSGafmRFLSRFRVHLGKVEKAMGVLLIIAGVVFLT 227
Cdd:PRK00293 319 AQSGDLLLGGLTLYLLALGMGLPLILITTFGN---KLLPKSGPWMNQVKTAFGFVLLALPVFLLE 380
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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