|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08268 |
PRK08268 |
3-hydroxy-acyl-CoA dehydrogenase; Validated |
1-497 |
0e+00 |
|
3-hydroxy-acyl-CoA dehydrogenase; Validated
Pssm-ID: 236211 [Multi-domain] Cd Length: 507 Bit Score: 591.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 1 MTAIEAGRTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATT 80
Cdd:PRK08268 1 MMALPSIATVAVIGAGAMGAGIAQVAAQAGHTVLLYDARAGAAAAARDGIAARLAKLVEKGKLTAEQADAALARLRPVEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 81 LPELADVALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSG 160
Cdd:PRK08268 81 LADLADCDLVVEAIVERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKHPERVAGLHFFNPVPLMKLVEVVSG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 161 FATDEAAATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIG 240
Cdd:PRK08268 161 LATDPAVADALYALARAWGKTPVRAKDTPGFIVNRAARPYYTEALRVLEEGVADPATIDAILREAAGFRMGPFELMDLIG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 241 QDVNEAVTRSVWEGFFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYDHAEGAAEPLPHTAEPCPAPAAVaVHTQLAGPAAV 320
Cdd:PRK08268 241 LDVNHAVMESVYRQFYQEPRFRPSLIQQELVAAGRLGRKSGQGFYRYADGAKQPPAEAAPPAALPPVW-VSADVEGDLAA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 321 VQELIEEAGIKVTRERAPGEHEGCIRLPGGARLALTDGqpATGDLSGPTIRFDLALDYRAATRIALAPGAEVSSQDVREA 400
Cdd:PRK08268 320 LARLLERLGATIETGEGPSADGLVLLAPTGGDTTTAAA--REGLDAARVVLIDLLLDYAAAKRRTLMAAPATSPAARDAA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 401 VGLFQALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSEWADGIGRHWLWHLLDSM 480
Cdd:PRK08268 398 HALFQQDGKAVSVIRDSPGFVAQRTVAMIVNEAADIAQQGIASPADIDLAMRLGLNYPLGPLAWGDRLGAARILRVLENL 477
|
490
....*....|....*..
gi 490083268 481 HHQYAGGRYAPSWALRR 497
Cdd:PRK08268 478 QALYGDPRYRPSPWLRR 494
|
|
| PaaC-3OHAcCoADH |
TIGR02279 |
3-hydroxyacyl-CoA dehydrogenase PaaC; This 3-hydroxyacyl-CoA dehydrogenase is involved in the ... |
9-497 |
1.58e-158 |
|
3-hydroxyacyl-CoA dehydrogenase PaaC; This 3-hydroxyacyl-CoA dehydrogenase is involved in the degradation of phenylacetic acid, presumably in steps following the opening of the phenyl ring. The sequences included in this model are all found in aparrent operons with other related genes such as paaA, paaB, paaD, paaE, paaF and paaN. Some genomes contain these other genes without an apparent paaC in the same operon - possibly in these cases a different dehydrogenase involved in fatty acid degradation may fill in the needed activity. This enzyme has domains which are members of the pfam02737 and pfam00725 families.
Pssm-ID: 188207 [Multi-domain] Cd Length: 503 Bit Score: 460.18 E-value: 1.58e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 9 TVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELADVA 88
Cdd:TIGR02279 7 TVAVIGAGAMGAGIAQVAASAGHQVLLYDIRAEALARAIAGIEARLNSLVTKGKLTAEECERTLKRLIPVTDLHALADAG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 89 LVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAAA 168
Cdd:TIGR02279 87 LVIEAIVENLEVKKALFAQLEELCPADTIIASNTSSLSITAIAAGLARPERVAGLHFFNPAPVMALVEVVSGLATAAEVA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 169 TTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVNEAVT 248
Cdd:TIGR02279 167 EQLYETALAWGKQPVHCHSTPGFIVNRVARPYYAEALRALEEQVAAPAVLDAALRDGAGFPMGPFELTDLIGHDVNFAVT 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 249 RSVWEGFFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYDHAEGAAEPLPHTAEPCPAPAAVAVHTQLaGPAAVVQELIEEA 328
Cdd:TIGR02279 247 CSVFNAFWQDRRFLPSLVQQELVIAGRLGRKSGLGVYDYREEAEAVVPLEAVSDSFSPRVTVVGDI-GAAAPLLARLEAA 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 329 GIKVTRERAPGEHEgcirlPGGARLALTDGQPATG----DLSGPTIRFDLALDYRAATRIALAPGAEVSSQDVREAVGLF 404
Cdd:TIGR02279 326 GIKVEKKSGMGVTQ-----IGDALLALTDGRTAQAraieLARPNLVLFDLVLDYSTGKRIAIAAAAVNPDSATRKAIYYL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 405 QALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSEWADGIGRHWLWHLLDSMHHQY 484
Cdd:TIGR02279 401 QQAGKKVLQIADYPGLLILRTVAMLANEAADAVLQGVASAQDIDTAMRLGVNYPYGPLAWAAQLGWQRILRVLENLQHHY 480
|
490
....*....|...
gi 490083268 485 AGGRYAPSWALRR 497
Cdd:TIGR02279 481 GEERYRPSSLLRR 493
|
|
| FadB |
COG1250 |
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ... |
8-286 |
6.81e-99 |
|
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440862 [Multi-domain] Cd Length: 281 Bit Score: 299.33 E-value: 6.81e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELADv 87
Cdd:COG1250 3 KKVAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEEEADAALARITPTTDLAALAD- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 88 alvveavveelsA-------------KQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPL 154
Cdd:COG1250 82 ------------AdlvieavpedldlKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 155 VEVVSGFATDEAAATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFE 234
Cdd:COG1250 150 VEVIRGPATSDETVATAVAFARRLGKTPVVVKDTPGFIVNRILVPYLNEAIRLLEEGVASPEDIDAAMRLGFGFPMGPFE 229
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 490083268 235 LMDLIGQDVNEAVTRSVWEGfFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYD 286
Cdd:COG1250 230 LADLVGLDTALAVLEVLYEA-LGDPRYRPPPLLKKLVEAGRLGRKTGRGFYD 280
|
|
| PRK05808 |
PRK05808 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
8-287 |
1.53e-65 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 180269 [Multi-domain] Cd Length: 282 Bit Score: 213.29 E-value: 1.53e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELADV 87
Cdd:PRK05808 4 QKIGVIGAGTMGNGIAQVCAVAGYDVVMVDISDAAVDRGLATITKSLDRLVKKGKMTEADKEAALARITGTTDLDDLKDA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 88 ALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAA 167
Cdd:PRK05808 84 DLVIEAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKRPDKVIGMHFFNPVPVMKLVEIIRGLATSDAT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 168 ATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVNEAV 247
Cdd:PRK05808 164 HEAVEALAKKIGKTPVEVKNAPGFVVNRILIPMINEAIFVLAEGVATAEDIDEGMKLGCNHPIGPLALADLIGLDTCLAI 243
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 490083268 248 TRSVWEGfFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYDH 287
Cdd:PRK05808 244 MEVLYEG-FGDSKYRPCPLLRKMVAAGWLGRKTGRGFYDY 282
|
|
| PLN02545 |
PLN02545 |
3-hydroxybutyryl-CoA dehydrogenase |
8-287 |
6.73e-62 |
|
3-hydroxybutyryl-CoA dehydrogenase
Pssm-ID: 215300 [Multi-domain] Cd Length: 295 Bit Score: 204.58 E-value: 6.73e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELADV 87
Cdd:PLN02545 5 KKVGVVGAGQMGSGIAQLAAAAGMDVWLLDSDPAALSRGLDSISSSLARLVKKGKMSQEEADATLGRIRCTTNLEELRDA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 88 ALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAA 167
Cdd:PLN02545 85 DFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQRPQQVIGMHFMNPPPIMKLVEIIRGADTSDEV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 168 ATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVNEAV 247
Cdd:PLN02545 165 FDATKALAERFGKTVVCSQDYPGFIVNRILMPMINEAFYALYTGVASKEDIDTGMKLGTNHPMGPLHLADFIGLDTCLSI 244
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 490083268 248 TRsVWEGFFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYDH 287
Cdd:PLN02545 245 MK-VLHEGLGDSKYRPCPLLVQYVDAGRLGRKSGRGVYHY 283
|
|
| PRK07530 |
PRK07530 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
1-296 |
8.07e-59 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181018 [Multi-domain] Cd Length: 292 Bit Score: 196.38 E-value: 8.07e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 1 MTAIeagRTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATT 80
Cdd:PRK07530 1 MMAI---KKVGVIGAGQMGNGIAHVCALAGYDVLLNDVSADRLEAGLATINGNLARQVAKGKISEEARAAALARISTATD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 81 LPELADVALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSG 160
Cdd:PRK07530 78 LEDLADCDLVIEAATEDETVKRKIFAQLCPVLKPEAILATNTSSISITRLASATDRPERFIGIHFMNPVPVMKLVELIRG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 161 FATDEAAATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIG 240
Cdd:PRK07530 158 IATDEATFEAAKEFVTKLGKTITVAEDFPAFIVNRILLPMINEAIYTLYEGVGSVEAIDTAMKLGANHPMGPLELADFIG 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 490083268 241 QDVNEAVTRSVWEGfFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYDHAegAAEPLP 296
Cdd:PRK07530 238 LDTCLSIMQVLHDG-LADSKYRPCPLLVKYVEAGWLGRKTGRGFYDYR--GEVPVP 290
|
|
| PRK07819 |
PRK07819 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
10-287 |
1.08e-54 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181133 [Multi-domain] Cd Length: 286 Bit Score: 185.19 E-value: 1.08e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 10 VAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELADVAL 89
Cdd:PRK07819 8 VGVVGAGQMGAGIAEVCARAGVDVLVFETTEELATAGRNRIEKSLERAVSRGKLTERERDAALARLRFTTDLGDFADRQL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 90 VVEAVVEELSAKQELFAALEDVVSE-DCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAAA 168
Cdd:PRK07819 88 VIEAVVEDEAVKTEIFAELDKVVTDpDAVLASNTSSIPIMKLAAATKRPGRVLGLHFFNPVPVLPLVELVPTLVTSEATV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 169 TTAYE-TAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVNEAV 247
Cdd:PRK07819 168 ARAEEfASDVLGKQVVRAQDRSGFVVNALLVPYLLSAIRMVESGFATAEDIDKAMVLGCAHPMGPLRLSDLVGLDTVKAI 247
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 490083268 248 TRSVWEGfFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYDH 287
Cdd:PRK07819 248 ADSMYEE-FKEPLYAPPPLLLRMVEAGLLGKKSGRGFYTY 286
|
|
| PRK06035 |
PRK06035 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
8-286 |
2.19e-52 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 180361 [Multi-domain] Cd Length: 291 Bit Score: 179.30 E-value: 2.19e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAI--GRR-LDRLVEKGKLPAAEREAARARLLPATTLPEL 84
Cdd:PRK06035 4 KVIGVVGSGVMGQGIAQVFARTGYDVTIVDVSEEILKNAMELIesGPYgLRNLVEKGKMSEDEAKAIMARIRTSTSYESL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 85 ADVALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATD 164
Cdd:PRK06035 84 SDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALERKDRFIGMHWFNPAPVMKLIEVVRAALTS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 165 EAAATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVN 244
Cdd:PRK06035 164 EETFNTTVELSKKIGKIPIEVADVPGFFTTRFIEGWLLEAIRSFEIGIATIKDIDEMCKLAFGFPMGPFELMDIIGIDTV 243
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 490083268 245 EAVTRSVWEGfFRDPKFTPSLAQRRLVEAGLLGRKAGQ-----GWYD 286
Cdd:PRK06035 244 YHIAEYLYEE-TGDPQFIPPNSLKQMVLNGYVGDKKVKygskgGWFD 289
|
|
| PRK09260 |
PRK09260 |
3-hydroxyacyl-CoA dehydrogenase; |
10-294 |
5.09e-47 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 236434 [Multi-domain] Cd Length: 288 Bit Score: 164.96 E-value: 5.09e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 10 VAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPE-LADVA 88
Cdd:PRK09260 4 LVVVGAGVMGRGIAYVFAVSGFQTTLVDIKQEQLESAQQEIASIFEQGVARGKLTEAARQAALARLSYSLDLKAaVADAD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 89 LVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAAA 168
Cdd:PRK09260 84 LVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTKRPERVIAMHFFNPVHKMKLVELIRGLETSDETV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 169 TTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVNEAVT 248
Cdd:PRK09260 164 QVAKEVAEQMGKETVVVNEFPGFVTSRISALVGNEAFYMLQEGVATAEDIDKAIRLGLNFPMGPLELGDLVGLDTRLNNL 243
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 490083268 249 RSVWEGFfrDPKFTPSLAQRRLVEAGLLGRKAGQGWYDHAEGAAEP 294
Cdd:PRK09260 244 KYLHETL--GEKYRPAPLLEKYVKAGRLGRKTGRGVYDYTNRENVP 287
|
|
| 3HCDH_N |
pfam02737 |
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ... |
9-188 |
6.00e-46 |
|
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.
Pssm-ID: 397037 [Multi-domain] Cd Length: 180 Bit Score: 158.47 E-value: 6.00e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 9 TVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELADVA 88
Cdd:pfam02737 1 KVAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRITEEEVDAALARISFTTDLAAAVDAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 89 LVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAAA 168
Cdd:pfam02737 81 LVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPETV 160
|
170 180
....*....|....*....|
gi 490083268 169 TTAYETAAAWGKSPVRSADT 188
Cdd:pfam02737 161 ATTVELAKKIGKTPVVVKDT 180
|
|
| PRK06130 |
PRK06130 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
8-286 |
4.03e-44 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 235707 [Multi-domain] Cd Length: 311 Bit Score: 158.01 E-value: 4.03e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATtlpeLADV 87
Cdd:PRK06130 5 QNLAIIGAGTMGSGIAALFARKGLQVVLIDVMEGALERARGVIERALGVYAPLGIASAGMGRIRMEAGLAAA----VSGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 88 ALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAA 167
Cdd:PRK06130 81 DLVIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPERFVGTHFFTPADVIPLVEVVRGDKTSPQT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 168 ATTAYETAAAWGKSPVR-SADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRM---GPFELMDLIGQDV 243
Cdd:PRK06130 161 VATTMALLRSIGKRPVLvKKDIPGFIANRIQHALAREAISLLEKGVASAEDIDEVVKWSLGIRLaltGPLEQRDMNGLDV 240
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 490083268 244 NEAVTRSVWEGFfrDPKFTPSLAQRRLVEAGLLGRKAGQGWYD 286
Cdd:PRK06130 241 HLAVASYLYQDL--ENRTTPSPLLEEKVEAGELGAKSGQGFYA 281
|
|
| fadB |
PRK11730 |
fatty acid oxidation complex subunit alpha FadB; |
8-291 |
1.82e-33 |
|
fatty acid oxidation complex subunit alpha FadB;
Pssm-ID: 183293 [Multi-domain] Cd Length: 715 Bit Score: 134.60 E-value: 1.82e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYD----ALPGRAAEAAGAIGRRldrlVEKGKLPAAEREAARARLLPATTLPE 83
Cdd:PRK11730 314 KQAAVLGAGIMGGGIAYQSASKGVPVIMKDinqkALDLGMTEAAKLLNKQ----VERGKIDGAKMAGVLSSIRPTLDYAG 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 84 LADVALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFAT 163
Cdd:PRK11730 390 FERVDVVVEAVVENPKVKAAVLAEVEQKVREDTILASNTSTISISLLAKALKRPENFCGMHFFNPVHRMPLVEVIRGEKT 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 164 DEAAATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEErAADPATIDAVLRESGGFRMGPFELMDLIGQDV 243
Cdd:PRK11730 470 SDETIATVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRD-GADFRQIDKVMEKQFGWPMGPAYLLDVVGIDT 548
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 490083268 244 NEAVTRSVWEGF-------FRDpkftpslAQRRLVEAGLLGRKAGQGWYDHAEGA 291
Cdd:PRK11730 549 AHHAQAVMAEGFpdrmkkdYRD-------AIDVLFEAKRFGQKNGKGFYRYEEDK 596
|
|
| 3HCDH |
pfam00725 |
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ... |
190-287 |
2.27e-33 |
|
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.
Pssm-ID: 395588 [Multi-domain] Cd Length: 97 Bit Score: 121.94 E-value: 2.27e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 190 GFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVNEAVTRsVWEGFFRDPKFTPSLAQRR 269
Cdd:pfam00725 1 GFVVNRLLAPYLNEAIRLVEEGVATPEDIDAAMRLGLGLPMGPFELSDLVGLDVGYHILE-VLAEEFGDRAYRPPPLLEK 79
|
90
....*....|....*...
gi 490083268 270 LVEAGLLGRKAGQGWYDH 287
Cdd:pfam00725 80 LVEAGRLGRKTGKGFYKY 97
|
|
| fa_ox_alpha_mit |
TIGR02441 |
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ... |
8-290 |
1.29e-31 |
|
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).
Pssm-ID: 131494 [Multi-domain] Cd Length: 737 Bit Score: 129.19 E-value: 1.29e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELADV 87
Cdd:TIGR02441 336 KTLAVLGAGLMGAGIAQVSVDKGLKTVLKDATPAGLDRGQQQVFKGLNKKVKRKKITSLERDSILSNLTPTLDYSGFKNA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 88 ALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAA 167
Cdd:TIGR02441 416 DMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDGTSKDT 495
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 168 ATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEErAADPATIDAvLRESGGFRMGPFELMDLIGQDVNEAV 247
Cdd:TIGR02441 496 LASAVAVGLKQGKVVIVVKDGPGFYTTRCLGPMLAEVIRLLQE-GVDPKKLDK-LTTKFGFPVGAATLADEVGVDVAEHV 573
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 490083268 248 TRSVWEGFfrDPKFTPSLAQ--RRLVEAGLLGRKAGQGWYDHAEG 290
Cdd:TIGR02441 574 AEDLGKAF--GERFGGGSAEllSELVKAGFLGRKSGKGIFIYQEG 616
|
|
| PRK08269 |
PRK08269 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
18-288 |
8.74e-30 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181340 [Multi-domain] Cd Length: 314 Bit Score: 118.62 E-value: 8.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 18 MGQGIAQVALVAGHPVRLYDALPGRA-------AEAAGAIGRRLDRLVEKGKLPAAEREAARA--RLLPATTLPE-LADV 87
Cdd:PRK08269 1 MGQGIALAFAFAGHDVTLIDFKPRDAagwraldAEARAEIERTLAALVALGRIDAAQADAVLAriAVVARDGAADaLADA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 88 ALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAA 167
Cdd:PRK08269 81 DLVFEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAHPERFLNAHWLNPAYLMPLVEVSPSDATDPAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 168 ATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFR---MGPFELMDLIGQDVN 244
Cdd:PRK08269 161 VDRLAALLERIGKVPVVCGPSPGYIVPRIQALAMNEAARMVEEGVASAEDIDKAIRTGFGLRfavLGLLEFIDWGGCDIL 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 490083268 245 EAVTRSVwEGFFRDPKFTPSLAQRRLVEAGLLGRKAGQGWYDHA 288
Cdd:PRK08269 241 YYASRYL-AGEIGPDRFAPPAIVVRNMEEGRDGLRTGAGFYDYA 283
|
|
| PRK06129 |
PRK06129 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
8-238 |
1.90e-27 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 235706 [Multi-domain] Cd Length: 308 Bit Score: 112.06 E-value: 1.90e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPE-LAD 86
Cdd:PRK06129 3 GSVAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGEAPDAVLARIRVTDSLADaVAD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 87 VALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEA 166
Cdd:PRK06129 83 ADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWTAPA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490083268 167 AATTAYETAAAWGKSPVR-SADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFR---MGPFELMDL 238
Cdd:PRK06129 163 TLARAEALYRAAGQSPVRlRREIDGFVLNRLQGALLREAFRLVADGVASVDDIDAVIRDGLGLRwsfMGPFETIDL 238
|
|
| fadJ |
PRK11154 |
fatty acid oxidation complex subunit alpha FadJ; |
8-285 |
5.52e-22 |
|
fatty acid oxidation complex subunit alpha FadJ;
Pssm-ID: 236864 [Multi-domain] Cd Length: 708 Bit Score: 99.59 E-value: 5.52e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALV-AGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELAD 86
Cdd:PRK11154 310 NKVGVLGGGLMGGGIAYVTATkAGLPVRIKDINPQGINHALKYSWDLLDKKVKRRHLKPSERDKQMALISGTTDYRGFKH 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 87 VALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEA 166
Cdd:PRK11154 390 ADVVIEAVFEDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAE 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 167 AATTAYETAAAWGKSPVRSADTPGFIVNRIARPFYAEALRVYEErAADPATIDAVLRESgGFRMGPFELMDLIGQDVNEA 246
Cdd:PRK11154 470 TIATTVALAKKQGKTPIVVRDGAGFYVNRILAPYINEAARLLLE-GEPIEHIDAALVKF-GFPVGPITLLDEVGIDVGTK 547
|
250 260 270
....*....|....*....|....*....|....*....
gi 490083268 247 VTRSVWEGFfrDPKFTPSLAQRRLVEAGLLGRKAGQGWY 285
Cdd:PRK11154 548 IIPILEAAL--GERFSAPAAFDKLLNDDRKGRKNGRGFY 584
|
|
| PRK08293 |
PRK08293 |
3-hydroxyacyl-CoA dehydrogenase; |
8-286 |
3.44e-18 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 181359 [Multi-domain] Cd Length: 287 Bit Score: 84.99 E-value: 3.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 8 RTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPELA-- 85
Cdd:PRK08293 4 KNVTVAGAGVLGSQIAFQTAFHGFDVTIYDISDEALEKAKERIAKLADRYVRDLEATKEAPAEAALNRITLTTDLAEAvk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 86 DVALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDE 165
Cdd:PRK08293 84 DADLVIEAVPEDPEIKGDFYEELAKVAPEKTIFATNSSTLLPSQFAEATGRPEKFLALHFANEIWKNNTAEIMGHPGTDP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 166 AAATTAYETAAAWGKSPVRSA-DTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFRMGPFELMDLIGQDVN 244
Cdd:PRK08293 164 EVFDTVVAFAKAIGMVPIVLKkEQPGYILNSLLVPFLSAALALWAKGVADPETIDKTWMIATGAPMGPFGILDIVGLDTA 243
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 490083268 245 EAVTrSVWeGFFRDPKFTPSLAQ--RRLVEAGLLGRKAGQGWYD 286
Cdd:PRK08293 244 YNIT-SNW-AEATDDENAKKAAAllKEYIDKGKLGVATGEGFYN 285
|
|
| 3HCDH_RFF |
pfam18321 |
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain; This domain is found in ... |
353-418 |
9.07e-17 |
|
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain; This domain is found in 3-hydroxybutyryl-CoA dehydrogenase present in E. coli. 3-hydroxybutyryl-CoA dehydrogenase catalyzes the second step in the biosynthesis of n-butanol from acetyl-CoA, in which acetoacetyl-CoA is reduced to 3-hydroxybutyryl-CoA. This domain is a reduced Rossmann-fold domain and, unlike the first Rossmann-fold domain, it is missing the catalytic residues and an NAD(H) binding cleft.
Pssm-ID: 436408 [Multi-domain] Cd Length: 69 Bit Score: 74.59 E-value: 9.07e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490083268 353 LALTDGQPAT---GDLSGPTIRFDLALDYRAATRIALAPGAEVSSQDVREAVGLFQALGKAVSVIEDVP 418
Cdd:pfam18321 1 LALTDGRTATqraAELGRPVVLFDLALDYDSATRLAVAPAAQCSPQALAQAVALLQALGKAVLVLADAP 69
|
|
| PLN02545 |
PLN02545 |
3-hydroxybutyryl-CoA dehydrogenase |
384-491 |
3.82e-14 |
|
3-hydroxybutyryl-CoA dehydrogenase
Pssm-ID: 215300 [Multi-domain] Cd Length: 295 Bit Score: 72.84 E-value: 3.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 384 IALAPGAEVSSQDVREAVGLFQALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSE 463
Cdd:PLN02545 152 VEIIRGADTSDEVFDATKALAERFGKTVVCSQDYPGFIVNRILMPMINEAFYALYTGVASKEDIDTGMKLGTNHPMGPLH 231
|
90 100
....*....|....*....|....*...
gi 490083268 464 WADGIGRHWLWHLLDSMHHQYAGGRYAP 491
Cdd:PLN02545 232 LADFIGLDTCLSIMKVLHEGLGDSKYRP 259
|
|
| PRK07066 |
PRK07066 |
L-carnitine dehydrogenase; |
1-242 |
3.18e-13 |
|
L-carnitine dehydrogenase;
Pssm-ID: 168796 [Multi-domain] Cd Length: 321 Bit Score: 70.63 E-value: 3.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 1 MTAIEAGRTVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGAIGRRLDRLVEKGKLPAAEREAararLLPATT 80
Cdd:PRK07066 1 MAVITDIKTFAAIGSGVIGSGWVARALAHGLDVVAWDPAPGAEAALRANVANAWPALERQGLAPGASPAR----LRFVAT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 81 LPE-LADVALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVS 159
Cdd:PRK07066 77 IEAcVADADFIQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARATHPERCVVGHPFNPVYLLPLVEVLG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 160 GFATDEAAATTAYETAAAWGKSPVR-SADTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFR---MGPFEL 235
Cdd:PRK07066 157 GERTAPEAVDAAMGIYRALGMRPLHvRKEVPGFIADRLLEALWREALHLVNEGVATTGEIDDAIRFGAGIRwsfMGTFLT 236
|
....*..
gi 490083268 236 MDLIGQD 242
Cdd:PRK07066 237 YTLAGGD 243
|
|
| FadB |
COG1250 |
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ... |
388-497 |
1.30e-12 |
|
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440862 [Multi-domain] Cd Length: 281 Bit Score: 68.21 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 388 PGAEVSSQDVREAVGLFQALGKAVSVIEDVPGLIVART-VAMIVDFAADAEaRGVASREDIDTAMRLGVNYPGGPSEWAD 466
Cdd:COG1250 154 RGPATSDETVATAVAFARRLGKTPVVVKDTPGFIVNRIlVPYLNEAIRLLE-EGVASPEDIDAAMRLGFGFPMGPFELAD 232
|
90 100 110
....*....|....*....|....*....|.
gi 490083268 467 GIGRHWLWHLLDSMHHQYAGGRYAPSWALRR 497
Cdd:COG1250 233 LVGLDTALAVLEVLYEALGDPRYRPPPLLKK 263
|
|
| PRK09260 |
PRK09260 |
3-hydroxyacyl-CoA dehydrogenase; |
384-503 |
3.45e-12 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 236434 [Multi-domain] Cd Length: 288 Bit Score: 67.12 E-value: 3.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 384 IALAPGAEVSSQDVREAVGLFQALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSE 463
Cdd:PRK09260 150 VELIRGLETSDETVQVAKEVAEQMGKETVVVNEFPGFVTSRISALVGNEAFYMLQEGVATAEDIDKAIRLGLNFPMGPLE 229
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 490083268 464 WADGIGrhwLWHLLDSMH--HQYAGGRYAPSWALRRSLKQNR 503
Cdd:PRK09260 230 LGDLVG---LDTRLNNLKylHETLGEKYRPAPLLEKYVKAGR 268
|
|
| 3HCDH |
pfam00725 |
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ... |
419-503 |
5.83e-12 |
|
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.
Pssm-ID: 395588 [Multi-domain] Cd Length: 97 Bit Score: 61.85 E-value: 5.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 419 GLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSEWADGIGRHWLWHLLDSMHHQYAGGRYAPSWALRRS 498
Cdd:pfam00725 1 GFVVNRLLAPYLNEAIRLVEEGVATPEDIDAAMRLGLGLPMGPFELSDLVGLDVGYHILEVLAEEFGDRAYRPPPLLEKL 80
|
....*
gi 490083268 499 LKQNR 503
Cdd:pfam00725 81 VEAGR 85
|
|
| PRK07531 |
PRK07531 |
carnitine 3-dehydrogenase; |
9-234 |
9.50e-12 |
|
carnitine 3-dehydrogenase;
Pssm-ID: 236044 [Multi-domain] Cd Length: 495 Bit Score: 67.07 E-value: 9.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 9 TVAVVGTGTMGQGIAQVALVAGHPVRLYDALPgraaEAAGAIGRRLDRLVEKGKLPAAEREAARARLLPATTLPE-LADV 87
Cdd:PRK07531 6 KAACIGGGVIGGGWAARFLLAGIDVAVFDPHP----EAERIIGEVLANAERAYAMLTDAPLPPEGRLTFCASLAEaVAGA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 88 ALVVEAVVEELSAKQELFAALEDVVSEDCLLATNTSSLSVTAVAGALRLPGRFVGLHFFNPAPLLPLVEVVSGFATDEAA 167
Cdd:PRK07531 82 DWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLPLVELVGGGKTSPET 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490083268 168 ATTAYETAAAWGKSPVRSA-DTPGFIVNRIARPFYAEALRVYEERAADPATIDAVLRESGGFR---MGPFE 234
Cdd:PRK07531 162 IRRAKEILREIGMKPVHIAkEIDAFVGDRLLEALWREALWLVKDGIATTEEIDDVIRYSFGLRwaqMGLFE 232
|
|
| PRK07530 |
PRK07530 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
400-469 |
1.74e-11 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181018 [Multi-domain] Cd Length: 292 Bit Score: 65.03 E-value: 1.74e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 400 AVGLFQALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSEWADGIG 469
Cdd:PRK07530 168 AKEFVTKLGKTITVAEDFPAFIVNRILLPMINEAIYTLYEGVGSVEAIDTAMKLGANHPMGPLELADFIG 237
|
|
| PRK05808 |
PRK05808 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
393-496 |
7.10e-11 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 180269 [Multi-domain] Cd Length: 282 Bit Score: 63.06 E-value: 7.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 393 SSQDVREAV-GLFQALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSEWADGIGRH 471
Cdd:PRK05808 159 TSDATHEAVeALAKKIGKTPVEVKNAPGFVVNRILIPMINEAIFVLAEGVATAEDIDEGMKLGCNHPIGPLALADLIGLD 238
|
90 100
....*....|....*....|....*
gi 490083268 472 WLWHLLDSMHHQYAGGRYAPSWALR 496
Cdd:PRK05808 239 TCLAIMEVLYEGFGDSKYRPCPLLR 263
|
|
| PRK07819 |
PRK07819 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
392-497 |
1.35e-07 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181133 [Multi-domain] Cd Length: 286 Bit Score: 53.07 E-value: 1.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 392 VSSQDVREAVGLF--QALGKAVSVIEDVPGLIVArtvAMIVDFAADA----EArGVASREDIDTAMRLGVNYPGGPSEWA 465
Cdd:PRK07819 161 VTSEATVARAEEFasDVLGKQVVRAQDRSGFVVN---ALLVPYLLSAirmvES-GFATAEDIDKAMVLGCAHPMGPLRLS 236
|
90 100 110
....*....|....*....|....*....|..
gi 490083268 466 DGIGRHWLWHLLDSMHHQYAGGRYAPSWALRR 497
Cdd:PRK07819 237 DLVGLDTVKAIADSMYEEFKEPLYAPPPLLLR 268
|
|
| PRK06035 |
PRK06035 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
384-497 |
4.28e-06 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 180361 [Multi-domain] Cd Length: 291 Bit Score: 48.33 E-value: 4.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 384 IALAPGAEVSSQDVREAVGLFQALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNYPGGPSE 463
Cdd:PRK06035 154 IEVVRAALTSEETFNTTVELSKKIGKIPIEVADVPGFFTTRFIEGWLLEAIRSFEIGIATIKDIDEMCKLAFGFPMGPFE 233
|
90 100 110
....*....|....*....|....*....|....
gi 490083268 464 WADGIGRHWLWHLLDSMHHQYAGGRYAPSWALRR 497
Cdd:PRK06035 234 LMDIIGIDTVYHIAEYLYEETGDPQFIPPNSLKQ 267
|
|
| MmsB |
COG2084 |
3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport ... |
9-49 |
4.73e-04 |
|
3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport and metabolism];
Pssm-ID: 441687 [Multi-domain] Cd Length: 285 Bit Score: 42.02 E-value: 4.73e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 490083268 9 TVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAEAAGA 49
Cdd:COG2084 3 KVGFIGLGAMGAPMARNLLKAGHEVTVWNRTPAKAEALVAA 43
|
|
| PRK06130 |
PRK06130 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
389-457 |
2.04e-03 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 235707 [Multi-domain] Cd Length: 311 Bit Score: 40.14 E-value: 2.04e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490083268 389 GAEVSSQDVREAVGLFQALGK-AVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLGVNY 457
Cdd:PRK06130 153 GDKTSPQTVATTMALLRSIGKrPVLVKKDIPGFIANRIQHALAREAISLLEKGVASAEDIDEVVKWSLGI 222
|
|
| PRK08269 |
PRK08269 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
386-454 |
2.94e-03 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181340 [Multi-domain] Cd Length: 314 Bit Score: 39.66 E-value: 2.94e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490083268 386 LAPGAEVS-----SQDVREAV-GLFQALGKAVSVIEDVPGLIVARTVAMIVDFAADAEARGVASREDIDTAMRLG 454
Cdd:PRK08269 144 LMPLVEVSpsdatDPAVVDRLaALLERIGKVPVVCGPSPGYIVPRIQALAMNEAARMVEEGVASAEDIDKAIRTG 218
|
|
| NAD_binding_2 |
pfam03446 |
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of ... |
9-51 |
3.48e-03 |
|
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.
Pssm-ID: 427298 [Multi-domain] Cd Length: 159 Bit Score: 38.22 E-value: 3.48e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 490083268 9 TVAVVGTGTMGQGIAQVALVAGHPVRLYDALPGRAAE--AAGAIG 51
Cdd:pfam03446 1 KIGFIGLGVMGSPMALNLLKAGYTVTVYNRTPEKVEElvAAGAIA 45
|
|
| |
