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Conserved domains on  [gi|490872517|ref|WP_004734523|]
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MULTISPECIES: ABC transporter ATP-binding protein [Vibrio]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-342 2.64e-156

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 441.84  E-value: 2.64e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR 80
Cdd:COG3842    2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:COG3842   78 NVGMVFQDYALFPHLTVAENVAFGLRmrGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:COG3842  158 LLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 239 GGSYLNAQRIS--ELEFETSLGVVEAKPQTEIEFGSACELLLRPQHIQ-ASYEQDSAIS--VLEQQFMGDHCRYVIE-AH 312
Cdd:COG3842  238 EANLLPGTVLGdeGGGVRTGGRTLEVPADAGLAAGGPVTVAIRPEDIRlSPEGPENGLPgtVEDVVFLGSHVRYRVRlGD 317

                        330       340       350
                 ....*....|....*....|....*....|....
gi 490872517 313 GQKLLA----TSSEALEVGMPVNVKVDTKGVLAF 342
Cdd:COG3842  318 GQELVVrvpnRAALPLEPGDRVGLSWDPEDVVVL 351
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-342 2.64e-156

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 441.84  E-value: 2.64e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR 80
Cdd:COG3842    2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:COG3842   78 NVGMVFQDYALFPHLTVAENVAFGLRmrGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:COG3842  158 LLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 239 GGSYLNAQRIS--ELEFETSLGVVEAKPQTEIEFGSACELLLRPQHIQ-ASYEQDSAIS--VLEQQFMGDHCRYVIE-AH 312
Cdd:COG3842  238 EANLLPGTVLGdeGGGVRTGGRTLEVPADAGLAAGGPVTVAIRPEDIRlSPEGPENGLPgtVEDVVFLGSHVRYRVRlGD 317

                        330       340       350
                 ....*....|....*....|....*....|....
gi 490872517 313 GQKLLA----TSSEALEVGMPVNVKVDTKGVLAF 342
Cdd:COG3842  318 GQELVVrvpnRAALPLEPGDRVGLSWDPEDVVVL 351
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-342 4.80e-110

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 324.68  E-value: 4.80e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR 80
Cdd:TIGR03265   1 SSPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITR----LPPQKR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFQDYALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:TIGR03265  77 DYGIVFQSYALFPNLTVADNIAYGLKNrgMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:TIGR03265 157 LLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVG 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  239 GGSYLNAQRISELEFETSLGVVEAKPQTEiEFGSACELLLRPQHIQASYEQDSA----ISVLEQQFMGDHCRYVIEAH-- 312
Cdd:TIGR03265 237 EVNWLPGTRGGGSRARVGGLTLACAPGLA-QPGASVRLAVRPEDIRVSPAGNAAnlllARVEDMEFLGAFYRLRLRLEgl 315

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 490872517  313 -GQKLLA--TSSE----ALEVGMPVNVKVDTKGVLAF 342
Cdd:TIGR03265 316 pGQALVAdvSASEverlGIRAGQPIWIELPAERLRAF 352
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 5-219 3.88e-106

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 309.45  E-value: 3.88e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGM 84
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG----VPPERRNIGM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03259   77 VFQDYALFPHLTVAENIAFGLKLrgVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDE 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03259  157 PLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-283 9.71e-96

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 288.77  E-value: 9.71e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   2 SCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRN 81
Cdd:PRK09452  12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITH----VPAENRH 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:PRK09452  88 VNTVFQSYALFPHMTVFENVAFGLRmqKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGG 239
Cdd:PRK09452 168 LDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGE 247

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 490872517 240 GSYLNAQ---RISELEFETSLGVVEAKPQTEIEF--GSACELLLRPQHI 283
Cdd:PRK09452 248 INIFDATvieRLDEQRVRANVEGRECNIYVNFAVepGQKLHVLLRPEDL 296
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
20-238 1.31e-82

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 254.23  E-value: 1.31e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGMIFQDYALFPHLTVNQ 99
Cdd:NF040840  16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITN----LPPEKRGIAYVYQNYMLFPHKTVFE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 100 NVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELIS 177
Cdd:NF040840  92 NIAFGLKlrKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIR 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 178 QIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:NF040840 172 EMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVG 232
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 20-165 5.05e-48

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 158.58  E-value: 5.05e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNIGMIFQDYALFPHLTVNQ 99
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE--RKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517  100 NVGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDR----YPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:pfam00005  79 NLRLGllLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
14-213 2.36e-46

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 156.80  E-value: 2.36e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  14 YESQTI----LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRN------IG 83
Cdd:NF038007  11 YITKTIktkvLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTN----LSYSQKIilrrelIG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:NF038007  87 YIFQSFNLIPHLSIFDNVALPLKyrGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLAD 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490872517 162 EPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSrEEAFAFADKMAVMNHG 213
Cdd:NF038007 167 EPTGNLDSKNARAVLQQLKYI-NQKGTTIIMVTHS-DEASTYGNRIINMKDG 216
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
14-200 1.53e-29

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 111.94  E-value: 1.53e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  14 YESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDGDNwlppeqRNIGMIFQDYAL-- 91
Cdd:NF040873   2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSG-------TVRRAGG------ARVAYVPQRSEVpd 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  92 -FPhLTVNQNVGFG-------LKDLSDQQKKEkVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:NF040873  69 sLP-LTVRDLVAMGrwarrglWRRLTRDDRAA-VDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEP 146

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 490872517 164 FSNIDTQVR---HELISQIRkifkKQGVTAIFVTHSREEA 200
Cdd:NF040873 147 TTGLDAESReriIALLAEEH----ARGATVVVVTHDLELV 182
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
8-222 1.86e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 101.35  E-value: 1.86e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRnIGMIFQ 87
Cdd:NF033858 270 RGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGD--IATRRR-VGYMSQ 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  88 DYALFPHLTVNQNVGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:NF033858 347 AFSLYGELTVRQNLELHarLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTS 426

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 166 NIDTQVR----HELISQIRkifkKQGVTaIFV-THSREEAfAFADKMAVMNHG----------VIEQYGSAS 222
Cdd:NF033858 427 GVDPVARdmfwRLLIELSR----EDGVT-IFIsTHFMNEA-ERCDRISLMHAGrvlasdtpaaLVAARGAAT 492
GguA NF040905
sugar ABC transporter ATP-binding protein;
20-213 3.36e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 82.14  E-value: 3.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSS--GIMSLN---CQ--TIDDGdnwlppEQRNIGMIFQDYALF 92
Cdd:NF040905  17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDgevCRfkDIRDS------EALGIVIIHQELALI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  93 PHLTVNQNVgFglkdLSDQQKKEKV----------QEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:NF040905  91 PYLSIAENI-F----LGNERAKRGVidwnetnrraRELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDE 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 163 PFSNI---DTQVRHELISQirkiFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:NF040905 166 PTAALneeDSAALLDLLLE----LKAQGITSIIISHKLNEIRRVADSITVLRDG 215
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-224 2.65e-14

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 74.01  E-value: 2.65e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMSLncqtidDGD---------- 72
Cdd:NF033858   1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGrVEVL------GGDmadarhrrav 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  73 ----NWLPpeQ---RNigmifqdyaLFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQ 143
Cdd:NF033858  75 cpriAYMP--QglgKN---------LYPTLSVFENLDFfgRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQ 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 144 RVAIARSLAYKPDLLLLDEPFSNIDTQVRH---ELISQIRKifKKQGVTAIFVTHSREEAFAFaDKMAVMNHGVIEQYGS 220
Cdd:NF033858 144 KLGLCCALIHDPDLLILDEPTTGVDPLSRRqfwELIDRIRA--ERPGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGT 220


                 ....
gi 490872517 221 ASEL 224
Cdd:NF033858 221 PAEL 224
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
107-224 3.40e-13

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 69.76  E-value: 3.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 107 DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFkKQ 186
Cdd:NF000106 115 DLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV-RD 193

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 490872517 187 GVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:NF000106 194 GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 29-199 3.97e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 63.16  E-value: 3.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    29 HGEIVCLLGASGCGKTTLLKAVAGLL-PLSSGIMSLNCQTIddgdnwlppeqrnigmifqdyalfphltvnqnvgfglkd 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELgPPGGGVIYIDGEDI--------------------------------------- 41

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   108 lsdqqkkekvQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQ- 186
Cdd:smart00382  42 ----------LEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLLLLl 111

                          170
                   ....*....|....*..
gi 490872517   187 ----GVTAIFVTHSREE 199
Cdd:smart00382 112 ksekNLTVILTTNDEKD 128
GguA NF040905
sugar ABC transporter ATP-binding protein;
137-215 1.06e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 44.01  E-value: 1.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 137 LSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINEL-AAEGKGVIVISSELPELLGMCDRIYVMNEGRI 482
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-342 2.64e-156

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 441.84  E-value: 2.64e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR 80
Cdd:COG3842    2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:COG3842   78 NVGMVFQDYALFPHLTVAENVAFGLRmrGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:COG3842  158 LLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 239 GGSYLNAQRIS--ELEFETSLGVVEAKPQTEIEFGSACELLLRPQHIQ-ASYEQDSAIS--VLEQQFMGDHCRYVIE-AH 312
Cdd:COG3842  238 EANLLPGTVLGdeGGGVRTGGRTLEVPADAGLAAGGPVTVAIRPEDIRlSPEGPENGLPgtVEDVVFLGSHVRYRVRlGD 317

                        330       340       350
                 ....*....|....*....|....*....|....
gi 490872517 313 GQKLLA----TSSEALEVGMPVNVKVDTKGVLAF 342
Cdd:COG3842  318 GQELVVrvpnRAALPLEPGDRVGLSWDPEDVVVL 351
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-342 9.52e-121

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 351.68  E-value: 9.52e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MScALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMslncqtIDDGD-NWLPPE 78
Cdd:COG3839    1 MA-SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGeIL------IGGRDvTDLPPK 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPD 156
Cdd:COG3839   74 DRNIAMVFQSYALYPHMTVYENIAFPLKlrKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPK 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 157 LLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADF 236
Cdd:COG3839  154 VFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGF 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 237 LGGGS--YLNAqRISELEFETSLGVVEAKPQTEIEFGSACELLLRPQHIQASYEQDSAIS--VLEQQFMGDHCRYVIEAH 312
Cdd:COG3839  234 IGSPPmnLLPG-TVEGGGVRLGGVRLPLPAALAAAAGGEVTLGIRPEHLRLADEGDGGLEatVEVVEPLGSETLVHVRLG 312

                        330       340       350
                 ....*....|....*....|....*....|..
gi 490872517 313 GQKLLA--TSSEALEVGMPVNVKVDTKGVLAF 342
Cdd:COG3839  313 GQELVArvPGDTRLRPGDTVRLAFDPERLHLF 344
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 1-335 4.94e-116

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 339.43  E-value: 4.94e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MScaLSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDdgdNWLPPEQR 80
Cdd:COG1118    1 MS--IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF---TNLPPRER 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPHLTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:COG1118   76 RVGFVFQHYALFPHMTVAENIAFGLRVRppSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:COG1118  156 LLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLG 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 239 GGSYLNAQRISElefETSLGVVEAKPQTEIEFGSAcELLLRPQHIQASYEQDS----AISVLEQQFMGDHCRYVIEAHG- 313
Cdd:COG1118  236 CVNVLRGRVIGG---QLEADGLTLPVAEPLPDGPA-VAGVRPHDIEVSREPEGentfPATVARVSELGPEVRVELKLEDg 311

                        330       340       350
                 ....*....|....*....|....*....|
gi 490872517 314 -QKLL-------ATSSEALEVGMPVNVKVD 335
Cdd:COG1118  312 eGQPLeaevtkeAWAELGLAPGDPVYLRPR 341
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-342 4.80e-110

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 324.68  E-value: 4.80e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR 80
Cdd:TIGR03265   1 SSPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITR----LPPQKR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFQDYALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:TIGR03265  77 DYGIVFQSYALFPNLTVADNIAYGLKNrgMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:TIGR03265 157 LLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVG 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  239 GGSYLNAQRISELEFETSLGVVEAKPQTEiEFGSACELLLRPQHIQASYEQDSA----ISVLEQQFMGDHCRYVIEAH-- 312
Cdd:TIGR03265 237 EVNWLPGTRGGGSRARVGGLTLACAPGLA-QPGASVRLAVRPEDIRVSPAGNAAnlllARVEDMEFLGAFYRLRLRLEgl 315

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 490872517  313 -GQKLLA--TSSE----ALEVGMPVNVKVDTKGVLAF 342
Cdd:TIGR03265 316 pGQALVAdvSASEverlGIRAGQPIWIELPAERLRAF 352
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 5-219 3.88e-106

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 309.45  E-value: 3.88e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGM 84
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG----VPPERRNIGM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03259   77 VFQDYALFPHLTVAENIAFGLKLrgVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDE 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03259  157 PLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-283 9.71e-96

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 288.77  E-value: 9.71e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   2 SCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRN 81
Cdd:PRK09452  12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITH----VPAENRH 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:PRK09452  88 VNTVFQSYALFPHMTVFENVAFGLRmqKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGG 239
Cdd:PRK09452 168 LDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGE 247

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 490872517 240 GSYLNAQ---RISELEFETSLGVVEAKPQTEIEF--GSACELLLRPQHI 283
Cdd:PRK09452 248 INIFDATvieRLDEQRVRANVEGRECNIYVNFAVepGQKLHVLLRPEDL 296
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 5-238 6.96e-93

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 276.43  E-value: 6.96e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGM 84
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITN----LPPHKRPVNT 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03300   77 VFQNYALFPHLTVFENIAFGLrlKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDE 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:cd03300  157 PLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 7-238 2.81e-92

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 274.99  E-value: 2.81e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGMIF 86
Cdd:cd03296    5 VRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATD----VPVQERNVGFVF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  87 QDYALFPHLTVNQNVGFGLK------DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:cd03296   81 QHYALFRHMTVFDNVAFGLRvkprseRPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:cd03296  161 DEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLG 238
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 4-210 2.13e-91

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 273.50  E-value: 2.13e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYES----QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlppeq 79
Cdd:COG1116    7 ALELRGVSKRFPTggggVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPG------- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:COG1116   80 PDRGVVFQEPALLPWLTVLDNVALGLElrGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEV 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVM 210
Cdd:COG1116  160 LLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL 212
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
5-317 7.88e-88

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 267.74  E-value: 7.88e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDDGDNWLPP--EQRNI 82
Cdd:PRK11432   7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEG------QIFIDGEDVTHRsiQQRDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:PRK11432  81 CMVFQSYALFPHMSLGENVGYGLKMLgvPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGGG 240
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 241 SYLNAQR------ISELEFETSLGVVEAKPQTEIEFGsacellLRPQHIQASYEQDSA--ISVLEQQFMGDHCRYVIEAH 312
Cdd:PRK11432 241 NIFPATLsgdyvdIYGYRLPRPAAFAFNLPDGECTVG------VRPEAITLSEQGEESqrCTIKHVAYMGPQYEVTVDWH 314


                 ....*
gi 490872517 313 GQKLL 317
Cdd:PRK11432 315 GQELL 319
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 35-317 1.39e-85

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 261.27  E-value: 1.39e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   35 LLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQ 112
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTN----VPPHLRHINMVFQSYALFPHMTVEENVAFGLKmrKVPRAE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  113 KKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIF 192
Cdd:TIGR01187  77 IKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVF 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  193 VTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGGGSYLNAQRISELEFETSLGVVEAKPQT-----E 267
Cdd:TIGR01187 157 VTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATVIERKSEQVVLAGVEGRRCDiytdvP 236

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517  268 IEFGSACELLLRPQHIQASYEQDSAIS------VLEQQFMGDHCRYVIE-AHGQKLL 317
Cdd:TIGR01187 237 VEKDQPLHVVLRPEKIVIEEEDEANSSnaiighVIDITYLGMTLEVHVRlETGQKVL 293
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 5-211 2.81e-85

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 256.63  E-value: 2.81e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYES----QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwlppEQR 80
Cdd:cd03293    1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG-------PGP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:cd03293   74 DRGYVFQQDALLPWLTVLDNVALGLElqGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVL 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMN 211
Cdd:cd03293  154 LLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLS 206
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 7-238 1.66e-84

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 255.49  E-value: 1.66e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGMIF 86
Cdd:TIGR00968   3 IANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATR----VHARDRKIGFVF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   87 QDYALFPHLTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:TIGR00968  79 QHYALFKHLTVRDNIAFGLEIRkhPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPF 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517  165 SNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:TIGR00968 159 GALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLG 232
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 7-252 2.25e-84

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 257.33  E-value: 2.25e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKY-ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RNIG 83
Cdd:COG1125    4 FENVTKRYpDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRD----LDPVElrRRIG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLD--EFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:COG1125   80 YVIQQIGLFPHMTVAENIATvpRLLGWDKERIRARVDELLELVGLDpeEYRDRYPHELSGGQQQRVGVARALAADPPILL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG- 238
Cdd:COG1125  160 MDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVGa 239

                        250
                 ....*....|....*.
gi 490872517 239 --GGSYLNAQRISELE 252
Cdd:COG1125  240 drGLRRLSLLRVEDLM 255
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 5-219 1.95e-83

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 251.79  E-value: 1.95e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSlncqtIDDGD-NWLPPEQRNIG 83
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIY-----IGGRDvTDLPPKDRDIA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:cd03301   76 MVFQNYALYPHMTVYDNIAFGLKlrKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 162 EPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03301  156 EPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
20-238 1.31e-82

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 254.23  E-value: 1.31e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGMIFQDYALFPHLTVNQ 99
Cdd:NF040840  16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITN----LPPEKRGIAYVYQNYMLFPHKTVFE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 100 NVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELIS 177
Cdd:NF040840  92 NIAFGLKlrKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIR 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 178 QIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:NF040840 172 EMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVG 232
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 5-238 2.83e-82

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 249.56  E-value: 2.83e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLtCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGM 84
Cdd:cd03299    1 LKVENL-SKDWKEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITN----LPPEKRDISY 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03299   76 VPQNYALFPHMTVYKNIAYGLKKRkvDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDE 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:cd03299  156 PFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLG 231
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
5-238 1.99e-81

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 252.45  E-value: 1.99e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGM 84
Cdd:PRK11607  20 LEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSH----VPPYQRPINM 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:PRK11607  96 MFQSYALFPHMTVEQNIAFGLKQdkLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDE 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:PRK11607 176 PMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIG 251
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 5-238 4.44e-79

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 241.44  E-value: 4.44e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY-ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RN 81
Cdd:cd03295    1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIRE----QDPVElrRK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLD--EFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:cd03295   77 IGYVIQQIGLFPHMTVEENIALVPKLLkwPKEKIRERADELLALVGLDpaEFADRYPHELSGGQQQRVGVARALAADPPL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFL 237
Cdd:cd03295  157 LLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFV 236


                 .
gi 490872517 238 G 238
Cdd:cd03295  237 G 237
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
19-238 4.09e-78

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 243.07  E-value: 4.09e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGMIFQDYALFPHLTVN 98
Cdd:PRK10851  17 VLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSR----LHARDRKVGFVFQHYALFRHMTVF 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  99 QNVGFGLKDLSDQQK------KEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR 172
Cdd:PRK10851  93 DNIAFGLTVLPRRERpnaaaiKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVR 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 173 HELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:PRK10851 173 KELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMG 238
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 7-283 1.14e-76

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 239.51  E-value: 1.14e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLncqTIDDGD-NWLPPEQRNIGMI 85
Cdd:TIGR03258   8 IDHLRVAYGANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAGLTGRI---AIADRDlTHAPPHKRGLALL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   86 FQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:TIGR03258  85 FQNYALFPHLKVEDNVAFGLRaqKMPKADIAERVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEP 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  164 FSNIDTQVRHELISQIRKIFKK-QGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGGGSY 242
Cdd:TIGR03258 165 LSALDANIRANMREEIAALHEElPELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFLGAANI 244

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 490872517  243 L--NAQRISE----LEFETSLGVVEA--KPQTEIEFGSACellLRPQHI 283
Cdd:TIGR03258 245 LpaIALGITEapglVDVSCGGAVIFAfgDGRHDGRDKLAC---IRPEHL 290
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
5-238 5.50e-75

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 230.80  E-value: 5.50e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTIleSLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGM 84
Cdd:COG3840    2 LRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTA----LPPAERPVSM 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKD---LSDQQKKeKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:COG3840   76 LFQENNLFPHLTVAQNIGLGLRPglkLTAEQRA-QVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLD 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 162 EPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:COG3840  155 EPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLG 231
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 23-219 1.50e-74

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 229.10  E-value: 1.50e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  23 LSLEVEhGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW--LPPEQRNIGMIFQDYALFPHLTVNQN 100
Cdd:cd03297   17 IDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKinLPPQQRKIGLVFQQYALFPHLNVREN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 101 VGFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIR 180
Cdd:cd03297   96 LAFGLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELK 175

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 490872517 181 KIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03297  176 QIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 1-237 1.54e-73

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 227.17  E-value: 1.54e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTID-DGDNW--LPP 77
Cdd:COG1127    2 SEPMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSG-------EILvDGQDItgLSE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  78 EQ-----RNIGMIFQDYALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIAR 149
Cdd:COG1127   75 KElyelrRRIGMLFQGGALFDSLTVFENVAFPLRehtDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALAR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 150 SLAYKPDLLLLDEPFSNID---TQVRHELISQIRkifKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELyF 226
Cdd:COG1127  155 ALALDPEILLYDEPTAGLDpitSAVIDELIRELR---DELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEEL-L 230

                        250
                 ....*....|.
gi 490872517 227 HPSSKFVADFL 237
Cdd:COG1127  231 ASDDPWVRQFL 241
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-286 1.29e-72

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 228.96  E-value: 1.29e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCaLSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDGD---NWLP 76
Cdd:PRK11650   1 MAG-LKLQAVRKSYDGKTqVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSG-------EIWIGGrvvNELE 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 PEQRNIGMIFQDYALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:PRK11650  73 PADRDIAMVFQNYALYPHMSVRENMAYGLKIrgMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVRE 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVA 234
Cdd:PRK11650 153 PAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVA 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 235 DFLGGGSY-LNAQRISE--LEFETSLGVVEAKPQ-TEIEFGSACELLLRPQHIQAS 286
Cdd:PRK11650 233 SFIGSPAMnLLDGRVSAdgAAFELAGGIALPLGGgYRQYAGRKLTLGIRPEHIALS 288
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
12-331 2.00e-72

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 228.76  E-value: 2.00e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  12 CK-YESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRNIGMIFQDYA 90
Cdd:PRK11000  10 TKaYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMND----VPPAERGVGMVFQSYA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  91 LFPHLTVNQNVGFGLK----DLSD-QQKKEKVQEMLELVHLDefgDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:PRK11000  86 LYPHLSVAENMSFGLKlagaKKEEiNQRVNQVAEVLQLAHLL---DRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 166 NIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGGGS---- 241
Cdd:PRK11000 163 NLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIGSPKmnfl 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 242 --YLNAQRISELEFETSLGV-----VEAkpqTEIEFGSACELLLRPQHIQASYEQDSAIS----VLEQqfMGDHCRYVIE 310
Cdd:PRK11000 243 pvKVTATAIEQVQVELPNRQqvwlpVEG---RGVQVGANMSLGIRPEHLLPSDIADVTLEgevqVVEQ--LGNETQIHIQ 317

                        330       340       350
                 ....*....|....*....|....*....|.
gi 490872517 311 AHGQK----------LLATSSEALEVGMPVN 331
Cdd:PRK11000 318 IPAIRqnlvyrqndvVLVEEGATFAIGLPPE 348
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 5-238 2.19e-70

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 219.10  E-value: 2.19e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQRNIGM 84
Cdd:COG1126    2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINKLRRKVGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGL---KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:COG1126   82 VFQQFNLFPHLTVLENVTLAPikvKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 162 EPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHsrEEAFAF--ADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLG 238
Cdd:COG1126  162 EPTSALDPELVGEVLDVMRDL-AKEGMTMVVVTH--EMGFARevADRVVFMDGGRIVEEGPPEEFFENPQHERTRAFLS 237
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 5-228 1.59e-69

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 225.55  E-value: 1.59e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYES-----QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW-LPPE 78
Cdd:COG1123  261 LEVRNLSKRYPVrgkggVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRsLREL 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQD--YALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLA 152
Cdd:COG1123  341 RRRVQMVFQDpySSLNPRMTVGDIIAEPLRlhgLLSRAERRERVAELLERVGLPpDLADRYPHELSGGQRQRVAIARALA 420

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 153 YKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:COG1123  421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANP 496
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 5-213 1.55e-68

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 212.43  E-value: 1.55e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQRNIGM 84
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRRRIGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGlkdlsdqqkkekvqemlelvhldefgdryphqLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:cd03229   81 VFQDFALFPHLTVLENIALG--------------------------------LSGGQQQRVALARALAMDPDVLLLDEPT 128

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490872517 165 SNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:cd03229  129 SALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDG 177
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
5-224 4.08e-68

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 213.39  E-value: 4.08e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGDNWLPPEQ--RNI 82
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEV-----RVLGEDVARDPAEvrRRI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:COG1131   76 GYVPQEPALYPDLTVRENLRFfaRLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLIL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG1131  156 DEPTSGLDPEARRELWELLREL-AAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 5-225 2.35e-67

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 211.04  E-value: 2.35e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNIG 83
Cdd:COG1122    1 IELENLSFSYPGGTpALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKN--LRELRRKVG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQ--DYALFpHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:COG1122   79 LVFQnpDDQLF-APTVEEDVAFGPEnlGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLV 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:COG1122  158 LDEPTAGLDPRGRRELLELLKRL-NKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVF 222
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-216 2.92e-67

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 210.67  E-value: 2.92e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKY----ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLP 76
Cdd:COG1136    1 MSPLLELRNLTKSYgtgeGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISS----LS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 PEQR------NIGMIFQDYALFPHLTVNQNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIA 148
Cdd:COG1136   77 ERELarlrrrHIGFVFQFFNLLPELTALENVALPLllAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 149 RSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSrEEAFAFADKMAVMNHGVIE 216
Cdd:COG1136  157 RALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDGRIV 223
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-224 1.86e-66

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 209.66  E-value: 1.86e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKY----ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIddGDNWLPPEQ 79
Cdd:COG1124    1 MLEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPV--TRRRRKAFR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDY--ALFPHLTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLAYKPD 156
Cdd:COG1124   79 RRVQMVFQDPyaSLHPRHTVDRILAEPLRIHGLPDREERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPE 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 157 LLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG1124  159 LLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADL 226
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 5-224 2.80e-66

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 208.51  E-value: 2.80e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW-LPPEQRNIG 83
Cdd:cd03261    1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAeLYRLRRRMG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:cd03261   81 MLFQSGALFDSLTVFENVAFPLRehtRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03261  161 DEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 24-330 4.25e-66

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 212.27  E-value: 4.25e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  24 SLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDN--WLPPEQRNIGMIFQDYALFPHLTVNQNV 101
Cdd:COG4148   19 DFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARgiFLPPHRRRIGYVFQEARLFPHLSVRGNL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 102 GFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRK 181
Cdd:COG4148   99 LYGRKRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLER 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 182 IFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGGGSYLNAqRISELEFETSLGVVE 261
Cdd:COG4148  179 LRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPLAGGEEAGSVLEA-TVAAHDPDYGLTRLA 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 262 AK------PQTEIEFGSACELLLRPQHIQASYEQDSAISVLEQ---------QFMGDHCRYVIEAHGQKLLAT----SSE 322
Cdd:COG4148  258 LGggrlwvPRLDLPPGTRVRVRIRARDVSLALEPPEGSSILNIlpgrvveiePADGGQVLVRLDLGGQTLLARitrrSAD 337

                        330
                 ....*....|
gi 490872517 323 AL--EVGMPV 330
Cdd:COG4148  338 ELglAPGQTV 347
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 5-200 1.96e-65

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 205.41  E-value: 1.96e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPL---SSGIMSLNCQTIDDgdnwLPPEQRN 81
Cdd:COG4136    2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRLTA----LPAEQRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFGL-KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:COG4136   78 IGILFQDDLLFPHLSVGENLAFALpPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLL 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 490872517 161 DEPFSNIDT----QVRHELISQIRkifkKQGVTAIFVTHSREEA 200
Cdd:COG4136  158 DEPFSKLDAalraQFREFVFEQIR----QRGIPALLVTHDEEDA 197
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 24-236 1.59e-64

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 205.18  E-value: 1.59e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  24 SLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQ---TIDDGDnwLPPEQRN-IGMIFQDYALFPHLTVNQ 99
Cdd:cd03294   44 SLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQdiaAMSRKE--LRELRRKkISMVFQSFALLPHRTVLE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 100 NVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELIS 177
Cdd:cd03294  122 NVAFGLevQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQD 201

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 178 QIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADF 236
Cdd:cd03294  202 ELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREF 260
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 5-217 3.76e-63

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 200.42  E-value: 3.76e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYE----SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDDGDNWLPPEQ- 79
Cdd:cd03257    2 LEVKNLSVSFPtgggSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSG------SIIFDGKDLLKLSRr 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 ------RNIGMIFQDY--ALFPHLTVNQNVGFGL----KDLSDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGGQQQRVA 146
Cdd:cd03257   76 lrkirrKEIQMVFQDPmsSLNPRMTIGEQIAEPLrihgKLSKKEARKEAVLLLLVGVGLPEeVLNRYPHELSGGQRQRVA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 147 IARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG-VIEQ 217
Cdd:cd03257  156 IARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGkIVEE 227
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-228 3.81e-63

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 208.99  E-value: 3.81e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQT--ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS---SGIMSLNCQTIDDgdnwL 75
Cdd:COG1123    1 MTPLLEVRDLSVRYPGGDvpAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLE----L 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  76 PPEQR--NIGMIFQD--YALFPhLTVNQNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIAR 149
Cdd:COG1123   77 SEALRgrRIGMVFQDpmTQLNP-VTVGDQIAEALenLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAM 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:COG1123  156 ALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAP 234
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 22-239 4.04e-63

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 204.70  E-value: 4.04e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   22 SLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTI--DDGDNWLPPEQRNIGMIFQDYALFPHLTVNQ 99
Cdd:TIGR01186  11 DADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENImkQSPVELREVRRKKIGMVFQQFALFPHMTILQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  100 NVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELIS 177
Cdd:TIGR01186  91 NTSLGPELLgwPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLIRDSMQD 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517  178 QIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGG 239
Cdd:TIGR01186 171 ELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGK 232
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 5-215 7.42e-63

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 198.91  E-value: 7.42e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQRNIGM 84
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINELRQKVGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGL---KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:cd03262   81 VFQQFNLFPHLTVLENITLAPikvKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 162 EPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHsrEEAFA--FADKMAVMNHGVI 215
Cdd:cd03262  161 EPTSALDPELVGEVLDVMKDL-AEEGMTMVVVTH--EMGFAreVADRVIFMDDGRI 213
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 5-215 9.53e-63

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 198.87  E-value: 9.53e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY----ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR 80
Cdd:cd03255    1 IELKNLSKTYggggEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISK----LSEKEL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 ------NIGMIFQDYALFPHLTVNQNV--GFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLA 152
Cdd:cd03255   77 aafrrrHIGFVFQSFNLLPDLTALENVelPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 153 YKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVI 215
Cdd:cd03255  157 NDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIELRDGKI 218
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 4-224 4.35e-61

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 196.03  E-value: 4.35e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RN 81
Cdd:COG1120    1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLAS----LSRRElaRR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFG-------LKDLSDQQKkEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:COG1120   77 IAYVPQEPPAPFGLTVRELVALGryphlglFGRPSAEDR-EAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQE 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG1120  156 PPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-210 7.65e-61

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 195.47  E-value: 7.65e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MScALSIKDLTCKYE----SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwlP 76
Cdd:COG4525    1 MS-MLTVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-----P 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 PEQRniGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:COG4525   75 GADR--GVVFQKDALLPWLNVLDNVAFGLRlrGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAAD 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVM 210
Cdd:COG4525  153 PRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVM 208
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 6-213 5.13e-60

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 191.53  E-value: 5.13e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQT--ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimSLNCQTIDDGDNWLPPEQRNIG 83
Cdd:cd03225    1 ELKNLSFSYPDGArpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSG--EVLVDGKDLTKLSLKELRRKVG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQ--DYALFpHLTVNQNVGFGLKDLSDQQK--KEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:cd03225   79 LVFQnpDDQFF-GPTVEEEVAFGLENLGLPEEeiEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:cd03225  158 LDEPTAGLDPAGRRELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIVLEDG 210
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
17-198 1.17e-59

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 191.03  E-value: 1.17e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  17 QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW-LPPEQRNIGMIFQDYALFPHL 95
Cdd:COG2884   15 REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRReIPYLRRRIGVVFQDFRLLPDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  96 TVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRH 173
Cdd:COG2884   95 TVYENVALPLRvtGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNLDPETSW 174

                        170       180
                 ....*....|....*....|....*
gi 490872517 174 ELISQIRKIfKKQGVTAIFVTHSRE 198
Cdd:COG2884  175 EIMELLEEI-NRRGTTVLIATHDLE 198
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-223 1.97e-59

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 191.46  E-value: 1.97e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDN---WLPp 77
Cdd:COG1121    3 MMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRrigYVP- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  78 eQRnigmiFQDYALFPhLTVNQNVGFGL-------KDLSDQQKkEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARS 150
Cdd:COG1121   82 -QR-----AEVDWDFP-ITVRDVVLMGRygrrglfRRPSRADR-EAVDEALERVGLEDLADRPIGELSGGQQQRVLLARA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 151 LAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEqYGSASE 223
Cdd:COG1121  154 LAQDPDLLLLDEPFAGVDAATEEALYELLREL-RREGKTILVVTHDLGAVREYFDRVLLLNRGLVA-HGPPEE 224
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 5-229 2.62e-58

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 188.17  E-value: 2.62e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQ----TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW-LPPEQ 79
Cdd:cd03258    2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKeLRKAR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:cd03258   82 RRIGMIFQHFNLLSSRTVFENVALPLEiaGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPS 229
Cdd:cd03258  162 LLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 5-228 2.35e-56

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 184.58  E-value: 2.35e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQT-----ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW-LPPE 78
Cdd:TIGR04521   1 IKLKNVSYIYQPGTpfekkALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKkLKDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   79 QRNIGMIFQ--DYALFpHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGGQQQRVAIARSLAY 153
Cdd:TIGR04521  81 RKKVGLVFQfpEHQLF-EETVYKDIAFGPKNlgLSEEEAEERVKEALELVGLDEeYLERSPFELSGGQMRRVAIAGVLAM 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517  154 KPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:TIGR04521 160 EPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 5-224 2.47e-55

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 180.82  E-value: 2.47e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLppeQRNIGM 84
Cdd:COG4555    2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREA---RRQIGV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:COG4555   79 LPDERGLYDRLTVRENIRYfaELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDE 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 163 PFSNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG4555  159 PTNGLDVMARRLLREILRA-LKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 5-228 5.97e-55

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 182.18  E-value: 5.97e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQ----TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLP---LSSGIMSLNCQTIDDgdnwLPP 77
Cdd:COG0444    2 LEVRNLKVYFPTRrgvvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLK----LSE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  78 EQ------RNIGMIFQD-Y-ALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHLD---EFGDRYPHQLSGGQQQ 143
Cdd:COG0444   78 KElrkirgREIQMIFQDpMtSLNPVMTVGDQIAEPLRihgGLSKAEARERAIELLERVGLPdpeRRLDRYPHELSGGMRQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 144 RVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:COG0444  158 RVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEE 237


                 ....*
gi 490872517 224 LYFHP 228
Cdd:COG0444  238 LFENP 242
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
5-238 2.89e-54

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 181.04  E-value: 2.89e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQ----TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ- 79
Cdd:COG1135    2 IELENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTA----LSEREl 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 ----RNIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAY 153
Cdd:COG1135   78 raarRKIGMIFQHFNLLSSRTVAENVALPLEiaGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALAN 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 154 KPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFV 233
Cdd:COG1135  158 NPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANPQSELT 237


                 ....*
gi 490872517 234 ADFLG 238
Cdd:COG1135  238 RRFLP 242
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
5-215 2.93e-54

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 176.93  E-value: 2.93e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RNI 82
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSA----MPPPEwrRQV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHlTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:COG4619   77 AYVPQEPALWGG-TVRDNLPFPFQLRERKFDRERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVLLLD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 162 EPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:COG4619  156 EPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 20-226 3.10e-54

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 177.66  E-value: 3.10e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwlPPEQRNIgmIFQDYALFPHLTVNQ 99
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITE-----PGPDRMV--VFQNYSLLPWLTVRE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  100 NVGFG----LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHEL 175
Cdd:TIGR01184  74 NIALAvdrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNL 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 490872517  176 ISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYF 226
Cdd:TIGR01184 154 QEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVPF 204
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
8-237 7.24e-54

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 176.82  E-value: 7.24e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlpPEQRNI----G 83
Cdd:PRK09493   5 KNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPK----VDERLIrqeaG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFG---LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:PRK09493  81 MVFQQFYLFPHLTALENVMFGplrVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 161 DEPFSNIDTQVRHELIsQIRKIFKKQGVTAIFVTHsrEEAFA--FADKMAVMNHGVIEQYGSASELYFHPSSKFVADFL 237
Cdd:PRK09493 161 DEPTSALDPELRHEVL-KVMQDLAEEGMTMVIVTH--EIGFAekVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFL 236
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
5-224 9.07e-54

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 176.31  E-value: 9.07e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTIleSLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTiddgDNWLPPEQRNIGM 84
Cdd:PRK10771   2 LKLTDITWLYHHLPM--RFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD----HTTTPPSRRPVSM 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLK---DLSDQQKkEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:PRK10771  76 LFQENNLFSHLTVAQNIGLGLNpglKLNAAQR-EKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLD 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 162 EPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK10771 155 EPFSALDPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 4-224 2.89e-53

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 175.63  E-value: 2.89e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTID-DGDNWLPPEQRN 81
Cdd:COG3638    2 MLELRNLSKRYPGGTpALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTaLRGRALRRLRRR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFG-LKDLS---------DQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSL 151
Cdd:COG3638   82 IGMIFQQFNLVPRLSVLTNVLAGrLGRTStwrsllglfPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIARAL 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG3638  162 VQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL 234
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 5-224 1.04e-52

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 173.39  E-value: 1.04e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRN--- 81
Cdd:cd03224    1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITG----LPPHERArag 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFGLKDLSDQQKKEKVQEMLELV-HLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:cd03224   77 IGYVPEGRRIFPELTVEENLLLGAYARRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLL 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03224  157 DEPSEGLAPKIVEEIFEAIREL-RDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 23-330 1.63e-52

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 176.84  E-value: 1.63e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDN--WLPPEQRNIGMIFQDYALFPHLTVNQN 100
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKgiFLPPEKRRIGYVFQEARLFPHLSVRGN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  101 VGFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIR 180
Cdd:TIGR02142  96 LRYGMKRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPYLE 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  181 KIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYfhPSSKFVADFLGGGSYLNAQRISELE-----FET 255
Cdd:TIGR02142 176 RLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVW--ASPDLPWLAREDQGSLIEGVVAEHDqhyglTAL 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  256 SLG-------VVEAKPQTEIEFG-SACELLLRPQHIQASyeqdSAISVLEQQFMG------DHCRYVIEAHGQKLLATSS 321
Cdd:TIGR02142 254 RLGgghlwvpENLGPTGARLRLRvPARDVSLALQKPEAT----SIRNILPARVVEiedsdiGRVGVVLESGGKTLWARIT 329

                         330
                  ....*....|....*
gi 490872517  322 E------ALEVGMPV 330
Cdd:TIGR02142 330 RwardelGIAPGTPV 344
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 5-224 1.86e-52

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 172.75  E-value: 1.86e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPL-----SSGIMSLNCQTIDDGDNWLPPEQ 79
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIYDLDVDVLELR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFPhLTVNQNVGFGLKD---LSDQQKKEKVQEMLELVHL-DEFGDR-YPHQLSGGQQQRVAIARSLAYK 154
Cdd:cd03260   81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLhgiKLKEELDERVEEALRKAALwDEVKDRlHALGLSGGQQQRLCLARALANE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 155 PDLLLLDEPFSNID---TQVRHELISQIRKifkkqGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03260  160 PEVLLLDEPTSALDpisTAKIEELIAELKK-----EYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 5-200 3.24e-52

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 171.51  E-value: 3.24e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQRNIGM 84
Cdd:COG4133    3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAR---EDYRRRLAY 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:COG4133   80 LGHADGLKPELTVRENLRFWAALYGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPF 159

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 490872517 165 SNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEA 200
Cdd:COG4133  160 TALDAAGVALLAELIAA-HLARGGAVLLTTHQPLEL 194
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 6-215 7.19e-52

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 170.79  E-value: 7.19e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLP--PEQRNIg 83
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGyvPQRRSI- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 mifqDYAlFPhLTVNQNVGFGL-------KDLSdQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPD 156
Cdd:cd03235   80 ----DRD-FP-ISVRDVVLMGLyghkglfRRLS-KADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPD 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 157 LLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03235  153 LLLLDEPFAGVDPKTQEDIYELLREL-RREGMTILVVTHDLGLVLEYFDRVLLLNRTVV 210
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 5-215 1.42e-51

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 168.73  E-value: 1.42e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGDNWLPPEQ--RNI 82
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEI-----KVLGKDIKKEPEEvkRRI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLTVNQNVgfglkdlsdqqkkekvqemlelvhldefgdryphQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03230   76 GYLPEEPSLYENLTVRENL----------------------------------KLSGGMKQRLALAQALLHDPELLILDE 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490872517 163 PFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03230  122 PTSGLDPESRREFWELLREL-KKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
1-237 1.49e-51

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 170.96  E-value: 1.49e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MScaLSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKaVAGLLPL-SSGIMSLNCQTIDDGDNwlPPEQ 79
Cdd:COG4161    1 MS--IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLR-VLNLLETpDSGQLNIAGHQFDFSQK--PSEK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 ------RNIGMIFQDYALFPHLTVNQNV---GFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARS 150
Cdd:COG4161   76 airllrQKVGMVFQQYNLWPHLTVMENLieaPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 151 LAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASeLYFHPSS 230
Cdd:COG4161  156 LMMEPQVLLFDEPTAALDPEITAQVVEIIREL-SQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDAS-HFTQPQT 233


                 ....*..
gi 490872517 231 KFVADFL 237
Cdd:COG4161  234 EAFAHYL 240
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 5-225 7.10e-51

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 169.92  E-value: 7.10e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQT--ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMSLNCQTIDDGDNWlppEQR- 80
Cdd:TIGR04520   1 IEVENVSFSYPESEkpALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGkVTVDGLDTLDEENLW---EIRk 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFQDyalfPH-----LTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAY 153
Cdd:TIGR04520  78 KVGMVFQN----PDnqfvgATVEDDVAFGLENLgvPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAM 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517  154 KPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQYGSASELY 225
Cdd:TIGR04520 154 RPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIF 224
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 4-237 2.32e-50

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 167.88  E-value: 2.32e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKaVAGLLPL-SSGIMSLNCQTIDDGDNWLPPE---- 78
Cdd:PRK11124   2 SIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLR-VLNLLEMpRSGTLNIAGNHFDFSKTPSDKAirel 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFPHLTVNQNV--------GfglkdLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARS 150
Cdd:PRK11124  81 RRNVGMVFQQYNLWPHLTVQQNLieapcrvlG-----LSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 151 LAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASElYFHPSS 230
Cdd:PRK11124 156 LMMEPQVLLFDEPTAALDPEITAQIVSIIREL-AETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC-FTQPQT 233


                 ....*..
gi 490872517 231 KFVADFL 237
Cdd:PRK11124 234 EAFKNYL 240
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 5-224 5.26e-50

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 166.97  E-value: 5.26e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLN-CQTIDDGDNWLPPEQRNI 82
Cdd:cd03256    1 IEVENLSKTYPNGKkALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDgTDINKLKGKALRQLRRQI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLTVNQNVGFG----------LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLA 152
Cdd:cd03256   81 GMIFQQFNLIERLSVLENVLSGrlgrrstwrsLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 153 YKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03256  161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
 19-195 1.43e-49

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 165.19  E-value: 1.43e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDD-GDNWLPPEQRNIGMIFQDYALFPHLTV 97
Cdd:TIGR02982  20 VLFDINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELHGaSKKQLVQLRRRIGYIFQAHNLLGFLTA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   98 NQNVGFGLK---DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHE 174
Cdd:TIGR02982 100 RQNVQMALElqpNLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEPTAALDSKSGRD 179

                         170       180
                  ....*....|....*....|.
gi 490872517  175 LISQIRKIFKKQGVTAIFVTH 195
Cdd:TIGR02982 180 VVELMQKLAKEQGCTILMVTH 200
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 23-215 2.50e-49

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 164.20  E-value: 2.50e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIddgdNWLPPEQRNIGMIFQDYALFPHLTVNQNVG 102
Cdd:cd03298   17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDV----TAAPPADRPVSMLFQENNLFAHLTVEQNVG 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 103 FGLK---DLSDQQKkEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQI 179
Cdd:cd03298   93 LGLSpglKLTAEDR-QAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLV 171

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 490872517 180 RKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03298  172 LDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 6-219 4.42e-49

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 162.60  E-value: 4.42e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRnigmi 85
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLAS----LSPKEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  86 fqdyalfphltvNQNVGFglkdlsdqqkkekVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:cd03214   72 ------------ARKIAY-------------VPQALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTS 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 166 NIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03214  127 HLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 20-228 5.84e-49

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 171.79  E-value: 5.84e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlSSGIMSLNCQTIDDGDNW-LPPEQRNIGMIFQD-YA-LFPHLT 96
Cdd:COG4172  302 VDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLSRRaLRPLRRRMQVVFQDpFGsLSPRMT 380

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  97 VNQNVGFGLK----DLSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQV 171
Cdd:COG4172  381 VGQIIAEGLRvhgpGLSAAERRARVAEALEEVGLDpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSV 460

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 172 RHELISQIRKIFKKQGVTAIFVTHS----ReeafAFADKMAVMNHG-VIEQyGSASELYFHP 228
Cdd:COG4172  461 QAQILDLLRDLQREHGLAYLFISHDlavvR----ALAHRVMVMKDGkVVEQ-GPTEQVFDAP 517
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
5-227 6.34e-49

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 165.19  E-value: 6.34e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYE--SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWlpPEQRNI 82
Cdd:PRK13635   6 IRVEHISFRYPdaATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVW--DVRRQV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQ--DYAlFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:PRK13635  84 GMVFQnpDNQ-FVGATVQDDVAFGLENigVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDII 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQYGSASELYFH 227
Cdd:PRK13635 163 ILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEILEEGTPEEIFKS 230
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 5-227 8.05e-49

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 164.01  E-value: 8.05e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTI-DDGDNWLPPEQRNI 82
Cdd:TIGR02315   2 LEVENLSKVYPNGKqALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDItKLRGKKLRKLRRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   83 GMIFQDYALFPHLTVNQNV-------------GFGLkdLSDQQKkEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIAR 149
Cdd:TIGR02315  82 GMIFQHYNLIERLTVLENVlhgrlgykptwrsLLGR--FSEEDK-ERALSALERVGLADKAYQRADQLSGGQQQRVAIAR 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517  150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFH 227
Cdd:TIGR02315 159 ALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELDDE 236
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 14-219 1.33e-48

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 162.34  E-value: 1.33e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   14 YESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqtiDDGDNWLPPEQRNIGMIFQDYALFP 93
Cdd:TIGR01277   8 YEYEHLPMEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVN----DQSHTGLAPYQRPVSMLFQENNLFA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   94 HLTVNQNVGFGLK---DLSDQQKkEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQ 170
Cdd:TIGR01277  84 HLTVRQNIGLGLHpglKLNAEQQ-EKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPL 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 490872517  171 VRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:TIGR01277 163 LREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-239 3.38e-48

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 162.61  E-value: 3.38e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MScALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDdGDNWLPPEQR 80
Cdd:PRK11264   1 MS-AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITID-TARSLSQQKG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NI-------GMIFQDYALFPHLTVNQNVGFG---LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARS 150
Cdd:PRK11264  79 LIrqlrqhvGFVFQNFNLFPHRTVLENIIEGpviVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 151 LAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGvTAIFVTHsrEEAFA--FADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK11264 159 LAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKR-TMVIVTH--EMSFArdVADRAIFMDQGRIVEQGPAKALFADP 235

                        250
                 ....*....|....*
gi 490872517 229 ----SSKFVADFLGG 239
Cdd:PRK11264 236 qqprTRQFLEKFLLQ 250
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 20-165 5.05e-48

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 158.58  E-value: 5.05e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNIGMIFQDYALFPHLTVNQ 99
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE--RKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517  100 NVGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDR----YPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:pfam00005  79 NLRLGllLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
4-213 1.03e-47

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 161.41  E-value: 1.03e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwlPPEQRniG 83
Cdd:PRK11248   1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEG-----PGAER--G 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:PRK11248  74 VVFQNEGLLPWRNVQDNVAFGLQlaGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLD 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490872517 162 EPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK11248 154 EPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 5-224 1.07e-47

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 160.92  E-value: 1.07e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRN--- 81
Cdd:COG0410    4 LEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITG----LPPHRIArlg 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQN---VGFGLKDLSDQqkKEKVQEMLELV-HLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:COG0410   80 IGYVPEGRRIFPSLTVEENlllGAYARRDRAEV--RADLERVYELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG0410  158 LLLDEPSLGLAPLIVEEIFEIIRRL-NREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAEL 223
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 5-224 1.21e-47

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 159.98  E-value: 1.21e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYES--QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLppeQRNI 82
Cdd:cd03263    1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAA---RQSL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:cd03263   78 GYCPQFDALFDELTVREHLRFyaRLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIfkKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03263  158 DEPTSGLDPASRRAIWDLILEV--RKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 6-213 1.38e-47

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 157.79  E-value: 1.38e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNIGMI 85
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLP--LEELRRRIGYV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  86 FQdyalfphltvnqnvgfglkdlsdqqkkekvqemlelvhldefgdryphqLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:cd00267   79 PQ-------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 490872517 166 NIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:cd00267  110 GLDPASRERLLELLREL-AEEGRTVIIVTHDPELAELAADRVIVLKDG 156
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 4-224 1.58e-47

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 170.40  E-value: 1.58e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ-- 79
Cdd:COG2274  473 DIELENVSFRYpgDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQ----IDPASlr 548

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFpHLTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIA 148
Cdd:COG2274  549 RQIGVVLQDVFLF-SGTIRENITLGDPDATD----EEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIA 623

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 149 RSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFkkQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG2274  624 RALLRNPRILILDEATSALDAETEAIILENLRRLL--KGRTVIIIAH-RLSTIRLADRIIVLDKGRIVEDGTHEEL 696
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 24-228 5.17e-47

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 161.82  E-value: 5.17e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  24 SLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ-----RNIGMIFQD-YA-LFPHLT 96
Cdd:COG4608   38 SFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITG----LSGRElrplrRRMQMVFQDpYAsLNPRMT 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  97 VNQNVGFGLK---DLSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR 172
Cdd:COG4608  114 VGDIIAEPLRihgLASKAERRERVAELLELVGLRpEHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQ 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 173 heliSQI----RKIFKKQGVTAIFVTHS----REeafaFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:COG4608  194 ----AQVlnllEDLQDELGLTYLFISHDlsvvRH----ISDRVAVMYLGKIVEIAPRDELYARP 249
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 4-225 1.97e-46

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 165.32  E-value: 1.97e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKY-ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPE--QR 80
Cdd:COG4988  336 SIELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSD----LDPAswRR 411

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFpHLTVNQNVGFGLKDLSDQQkkekVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIAR 149
Cdd:COG4988  412 QIAWVPQNPYLF-AGTIRENLRLGRPDASDEE----LEAALEAAGLDEFVAALPDgldtplgeggrGLSGGQAQRLALAR 486

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:COG4988  487 ALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITH-RLALLAQADRILVLDDGRIVEQGTHEELL 559
cbiO PRK13637
energy-coupling factor transporter ATPase;
1-225 2.32e-46

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 159.06  E-value: 2.32e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MScaLSIKDLTCKYESQTILES-----LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWL 75
Cdd:PRK13637   1 MS--IKIENLTHIYMEGTPFEKkaldnVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  76 PPEQRNIGMIFQ--DYALFPHlTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLD--EFGDRYPHQLSGGQQQRVAIAR 149
Cdd:PRK13637  79 SDIRKKVGLVFQypEYQLFEE-TIEKDIAFGPINLglSEEEIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAG 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13637 158 VVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
14-213 2.36e-46

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 156.80  E-value: 2.36e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  14 YESQTI----LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRN------IG 83
Cdd:NF038007  11 YITKTIktkvLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTN----LSYSQKIilrrelIG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:NF038007  87 YIFQSFNLIPHLSIFDNVALPLKyrGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLAD 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490872517 162 EPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSrEEAFAFADKMAVMNHG 213
Cdd:NF038007 167 EPTGNLDSKNARAVLQQLKYI-NQKGTTIIMVTHS-DEASTYGNRIINMKDG 216
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
32-228 3.19e-46

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 160.42  E-value: 3.19e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  32 IVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDN--WLPPEQRNIGMIFQDYALFPHLTVNQNVGFGLKDlS 109
Cdd:PRK11144  26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKgiCLPPEKRRIGYVFQDARLFPHYKVRGNLRYGMAK-S 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 110 DQQKKEKVQEMLELVHLDefgDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVT 189
Cdd:PRK11144 105 MVAQFDKIVALLGIEPLL---DRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIP 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 490872517 190 AIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY----FHP 228
Cdd:PRK11144 182 ILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWassaMRP 224
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-215 9.62e-46

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 156.35  E-value: 9.62e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR 80
Cdd:COG0411    1 SDPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITG----LPPHRI 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 N---IGMIFQDYALFPHLTVNQNV-----------------GFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGG 140
Cdd:COG0411   77 ArlgIARTFQNPRLFPELTVLENVlvaaharlgrgllaallRLPRARREEREARERAEELLERVGLADRADEPAGNLSYG 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 141 QQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:COG0411  157 QQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRV 231
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 7-224 1.53e-45

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 154.84  E-value: 1.53e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLN-----CQTIDdgdnwlppEQRN 81
Cdd:cd03265    3 VENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAghdvvREPRE--------VRRR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:cd03265   75 IGIVFQDLSVDDELTGWENLYIhaRLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLF 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03265  155 LDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 20-228 3.25e-45

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 157.66  E-value: 3.25e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG--------IMSLNcqtiddgDNWLPPEQRNIGMIFQDYAL 91
Cdd:PRK11153  21 LNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGrvlvdgqdLTALS-------EKELRKARRQIGMIFQHFNL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  92 FPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDT 169
Cdd:PRK11153  94 LSSRTVFDNVALPLElaGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDP 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 170 QVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG-VIEQyGSASELYFHP 228
Cdd:PRK11153 174 ATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGrLVEQ-GTVSEVFSHP 232
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 4-224 3.72e-45

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 162.24  E-value: 3.72e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ-- 79
Cdd:COG4987  333 SLELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRD----LDEDDlr 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFpHLTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIA 148
Cdd:COG4987  409 RRIAVVPQRPHLF-DTTLRENLRLARPDATD----EELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALA 483

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 149 RSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFkkQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG4987  484 RALLRDAPILLLDEPTEGLDAATEQALLADLLEAL--AGRTVLLITH-RLAGLERMDRILVLEDGRIVEQGTHEEL 556
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-225 3.99e-45

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 155.66  E-value: 3.99e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQT---ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDDGDNwLPP 77
Cdd:PRK13650   1 MSNIIEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESG------QIIIDGDL-LTE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  78 E-----QRNIGMIFQDY-ALFPHLTVNQNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIAR 149
Cdd:PRK13650  74 EnvwdiRHKIGMVFQNPdNQFVGATVEDDVAFGLenKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAG 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13650 154 AVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELF 228
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 5-213 1.26e-44

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 152.98  E-value: 1.26e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQRN--- 81
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITG----LPPHEIArlg 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNV----------GFGLKDLSDQQKK--EKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIAR 149
Cdd:cd03219   77 IGRTFQIPRLFPELTVLENVmvaaqartgsGLLLARARREEREarERAEELLERVGLADLADRPAGELSYGQQRRLEIAR 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:cd03219  157 ALATDPKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQG 219
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 18-217 1.94e-44

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 152.20  E-value: 1.94e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  18 TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNwlppEQR------NIGMIFQDYAL 91
Cdd:COG4181   26 TILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDE----DARarlrarHVGFVFQSFQL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  92 FPHLTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQV 171
Cdd:COG4181  102 LPTLTALENVMLPLELAGRRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAAT 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 490872517 172 RHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQ 217
Cdd:COG4181  182 GEQIIDLLFELNRERGTTLVLVTHDPALA-ARCDRVLRLRAGRLVE 226
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 5-224 3.92e-44

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 151.52  E-value: 3.92e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR---N 81
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITK----LPPHERaraG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   82 IGMIFQDYALFPHLTVNQNVGFGLkDLSDQQKKEKVQEMLEL--VhLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:TIGR03410  77 IAYVPQGREIFPRLTVEENLLTGL-AALPRRSRKIPDEIYELfpV-LKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517  160 LDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:TIGR03410 155 LDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 5-231 4.18e-44

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 152.27  E-value: 4.18e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYES---------QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwL 75
Cdd:TIGR02769   3 LEVRDVTHTYRTgglfgakqrAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQ----L 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   76 PPEQ-----RNIGMIFQDY--ALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHL-DEFGDRYPHQLSGGQQQR 144
Cdd:TIGR02769  79 DRKQrrafrRDVQLVFQDSpsAVNPRMTVRQIIGEPLRhltSLDESEQKARIAELLDMVGLrSEDADKLPRQLSGGQLQR 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  145 VAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG-VIEQYGSASE 223
Cdd:TIGR02769 159 INIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGqIVEECDVAQL 238


                  ....*....
gi 490872517  224 LYF-HPSSK 231
Cdd:TIGR02769 239 LSFkHPAGR 247
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 19-213 4.91e-44

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 150.48  E-value: 4.91e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDD-GDNWLPPEQRNIGMIFQDYALFPHLTV 97
Cdd:TIGR02673  17 ALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRlRGRQLPLLRRRIGVVFQDFRLLPDRTV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   98 NQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHEL 175
Cdd:TIGR02673  97 YENVALPLEvrGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEPTGNLDPDLSERI 176

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 490872517  176 IsQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:TIGR02673 177 L-DLLKRLNKRGTTVIVATHDLSLVDRVAHRVIILDDG 213
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 4-239 6.77e-44

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 151.29  E-value: 6.77e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGI-----MSLNCQTIDDGDNWLPPE 78
Cdd:TIGR00972   1 AIEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLNRMNDLVPGVriegkVLFDGQDIYDKKIDVVEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   79 QRNIGMIFQDYALFPhLTVNQNVGFGLKDLSDQQKK---EKVQEMLELVHL-DEFGDR---YPHQLSGGQQQRVAIARSL 151
Cdd:TIGR00972  81 RRRVGMVFQKPNPFP-MSIYDNIAYGPRLHGIKDKKeldEIVEESLKKAALwDEVKDRlhdSALGLSGGQQQRLCIARAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  152 AYKPDLLLLDEPFSNID---TQVRHELISQIRKIFkkqgvTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:TIGR00972 160 AVEPEVLLLDEPTSALDpiaTGKIEELIQELKKKY-----TIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNP 234

                         250
                  ....*....|.
gi 490872517  229 SSKFVADFLGG 239
Cdd:TIGR00972 235 KEKRTEDYISG 245
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 7-228 7.32e-44

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 152.48  E-value: 7.32e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQTILESLSL-----EVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW--LPPEQ 79
Cdd:PRK13634   5 FQKVEHRYQYKTPFERRALydvnvSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNkkLKPLR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQ--DYALFPHlTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:PRK13634  85 KKVGIVFQfpEHQLFEE-TVEKDICFGPMNfgVSEEDAKQKAREMIELVGLPEeLLARSPFELSGGQMRRVAIAGVLAME 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK13634 164 PEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 7-198 1.89e-43

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 148.92  E-value: 1.89e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDDGDNWLPPE-------Q 79
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSG------QVYLNGQETPPLNskkaskfR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   80 RN-IGMIFQDYALFPHLTVNQN--VGFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPD 156
Cdd:TIGR03608  75 REkLGYLFQNFALIENETVEENldLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPP 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 490872517  157 LLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSRE 198
Cdd:TIGR03608 155 LILADEPTGSLDPKNRDEVLDLLLEL-NDEGKTIIIVTHDPE 195
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
3-240 6.04e-43

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 149.18  E-value: 6.04e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   3 CALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTID---DGDNWLPPEQ 79
Cdd:COG4598    7 PALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRlkpDRDGELVPAD 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 R--------NIGMIFQDYALFPHLTVNQNVGFG----LKdLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAI 147
Cdd:COG4598   87 RrqlqrirtRLGMVFQSFNLWSHMTVLENVIEApvhvLG-RPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHsrEEAFA--FADKMAVMNHGVIEQYGSASELY 225
Cdd:COG4598  166 ARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDL-AEEGRTMLVVTH--EMGFArdVSSHVVFLHQGRIEEQGPPAEVF 242

                        250
                 ....*....|....*
gi 490872517 226 FHPSSKFVADFLGGG 240
Cdd:COG4598  243 GNPKSERLRQFLSSS 257
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
4-224 7.44e-43

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 156.09  E-value: 7.44e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKY-ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--R 80
Cdd:COG1132  339 EIEFENVSFSYpGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRD----LTLESlrR 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFpHLTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPHQ-----------LSGGQQQRVAIAR 149
Cdd:COG1132  415 QIGVVPQDTFLF-SGTIRENIRYGRPDATD----EEVEEAAKAAQAHEFIEALPDGydtvvgergvnLSGGQRQRIAIAR 489

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG1132  490 ALLKDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAH-RLSTIRNADRILVLDDGRIVEQGTHEEL 561
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 4-239 8.23e-43

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 148.65  E-value: 8.23e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKavagllplssgimSLN--CQTID----------DG 71
Cdd:COG1117   11 KIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLR-------------CLNrmNDLIPgarvegeillDG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  72 DNWLPPEQ------RNIGMIFQDYALFPHlTVNQNVGFGLKD---LSDQQKKEKVQEMLELVHL-DEFGDR---YPHQLS 138
Cdd:COG1117   78 EDIYDPDVdvvelrRRVGMVFQKPNPFPK-SIYDNVAYGLRLhgiKSKSELDEIVEESLRKAALwDEVKDRlkkSALGLS 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 139 GGQQQRVAIARSLAYKPDLLLLDEPFSNID---TQVRHELISQIRKIFkkqgvTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:COG1117  157 GGQQQRLCIARALAVEPEVLLMDEPTSALDpisTAKIEELILELKKDY-----TIVIVTHNMQQAARVSDYTAFFYLGEL 231

                        250       260
                 ....*....|....*....|....
gi 490872517 216 EQYGSASELYFHPSSKFVADFLGG 239
Cdd:COG1117  232 VEFGPTEQIFTNPKDKRTEDYITG 255
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 5-215 1.82e-42

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 147.90  E-value: 1.82e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDGDNWLPPEQRNIGM 84
Cdd:PRK11247  13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAG-------ELLAGTAPLAEAREDTRL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKDlsdqQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:PRK11247  86 MFQDARLLPWKKVIDNVGLGLKG----QWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490872517 165 SNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:PRK11247 162 GALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
1-228 2.66e-42

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 147.68  E-value: 2.66e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQT---------ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDG 71
Cdd:COG4167    1 MSALLEVRNLSKTFKYRTglfrrqqfeAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  72 DNwlppEQR--NIGMIFQD--YALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHL-DEFGDRYPHQLSGGQQQ 143
Cdd:COG4167   81 DY----KYRckHIRMIFQDpnTSLNPRLNIGQILEEPLRlntDLTAEEREERIFATLRLVGLlPEHANFYPHMLSSGQKQ 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 144 RVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:COG4167  157 RVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAE 236


                 ....*
gi 490872517 224 LYFHP 228
Cdd:COG4167  237 VFANP 241
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 5-213 3.39e-42

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 144.45  E-value: 3.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYES--QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGD-NWLppeQRN 81
Cdd:cd03228    1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDlESL---RKN 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFpHLTVNQNVgfglkdlsdqqkkekvqemlelvhldefgdryphqLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:cd03228   78 IAYVPQDPFLF-SGTIRENI-----------------------------------LSGGQRQRIAIARALLRDPPILILD 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490872517 162 EPFSNIDTQVRHELISQIRKIfkKQGVTAIFVTHsREEAFAFADKMAVMNHG 213
Cdd:cd03228  122 EATSALDPETEALILEALRAL--AKGKTVIVIAH-RLSTIRDADRIIVLDDG 170
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 20-198 1.22e-41

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 144.47  E-value: 1.22e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDD-GDNWLPPEQRNIGMIFQDYALFPHLTVN 98
Cdd:cd03292   17 LDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlRGRAIPYLRRKIGVVFQDFRLLPDRNVY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  99 QNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHElI 176
Cdd:cd03292   97 ENVAFALEvtGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWE-I 175

                        170       180
                 ....*....|....*....|..
gi 490872517 177 SQIRKIFKKQGVTAIFVTHSRE 198
Cdd:cd03292  176 MNLLKKINKAGTTVVVATHAKE 197
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 6-215 1.13e-40

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 141.63  E-value: 1.13e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDGDNWLPPEQR--NI 82
Cdd:cd03226    1 RIENISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSG-------SILLNGKPIKAKERrkSI 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQD--YALFPHlTVNQNVGFGLKDLSDqqKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:cd03226   74 GYVMQDvdYQLFTD-SVREELLLGLKELDA--GNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIF 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 161 DEPFSNIDTqvRH-ELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03226  151 DEPTSGLDY--KNmERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAI 204
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
24-239 1.96e-40

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 146.33  E-value: 1.96e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  24 SLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG---IMSLNCQTIDDGDnWLPPEQRNIGMIFQDYALFPHLTVNQN 100
Cdd:PRK10070  48 SLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGqvlIDGVDIAKISDAE-LREVRRKKIAMVFQSFALMPHMTVLDN 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 101 VGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQ 178
Cdd:PRK10070 127 TAFGmeLAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDE 206

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 179 IRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGG 239
Cdd:PRK10070 207 LVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRG 267
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 4-223 3.36e-40

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 141.83  E-value: 3.36e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnWLPPEQ-RNI 82
Cdd:PRK13548   2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLAD---WSPAELaRRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYAL-FPhLTVNQNVGFGLKDLSDQQKKEK--VQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLA------Y 153
Cdd:PRK13548  79 AVLPQHSSLsFP-FTVEEVVAMGRAPHGLSRAEDDalVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdG 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 154 KPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:PRK13548 158 PPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAE 227
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
8-225 4.64e-40

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 142.15  E-value: 4.64e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYE------SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSL-NCQTIDDGDNWlppEQR 80
Cdd:PRK13633   8 KNVSYKYEsneestEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVdGLDTSDEENLW---DIR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 N-IGMIFQ--DYALFPHLtVNQNVGFGLKDLSDQQK--KEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKP 155
Cdd:PRK13633  85 NkAGMVFQnpDNQIVATI-VEEDVAFGPENLGIPPEeiRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRP 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 156 DLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13633 164 ECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGTPKEIF 232
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 4-224 5.04e-40

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 142.05  E-value: 5.04e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgDNwLPPEQRN 81
Cdd:PRK13632   7 MIKVENVSFSYpnSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK-EN-LKEIRKK 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDY-ALFPHLTVNQNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:PRK13632  85 IGIIFQNPdNQFIGATVEDDIAFGLenKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEII 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFaFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK13632 165 IFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEI 229
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
10-231 8.49e-40

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 141.36  E-value: 8.49e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  10 LTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTID--DGDNWlPPEQRNIGMIFQ 87
Cdd:PRK10419  18 LSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAklNRAQR-KAFRRDIQMVFQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  88 DY--ALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:PRK10419  97 DSisAVNPRKTVREIIREPLRhllSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILD 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 162 EPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI--EQYGSASELYFHPSSK 231
Cdd:PRK10419 177 EAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIveTQPVGDKLTFSSPAGR 248
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 4-224 6.36e-39

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 138.29  E-value: 6.36e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTID----DGDNWLPPEQ 79
Cdd:COG1119    3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYG------NDVRlfgeRRGGEDVWEL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 R-NIGMIfqDYALFPHLTVNQNV------GF----GL-KDLSDQQKkEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAI 147
Cdd:COG1119   77 RkRIGLV--SPALQLRFPRDETVldvvlsGFfdsiGLyREPTDEQR-ERARELLELLGLAHLADRPFGTLSQGEQRRVLI 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG1119  154 ARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEV 230
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
5-239 8.04e-39

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 138.56  E-value: 8.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTID---DGDNWLPPEQRN 81
Cdd:PRK10619   6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrDKDGQLKVADKN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 --------IGMIFQDYALFPHLTVNQNV---GFGLKDLSDQQKKEKVQEMLELVHLDEFG-DRYPHQLSGGQQQRVAIAR 149
Cdd:PRK10619  86 qlrllrtrLTMVFQHFNLWSHMTVLENVmeaPIQVLGLSKQEARERAVKYLAKVGIDERAqGKYPVHLSGGQQQRVSIAR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 150 SLAYKPDLLLLDEPFSNIDTqvrhELISQIRKIFKK---QGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYF 226
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDP----ELVGEVLRIMQQlaeEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFG 241

                        250
                 ....*....|...
gi 490872517 227 HPSSKFVADFLGG 239
Cdd:PRK10619 242 NPQSPRLQQFLKG 254
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 5-231 1.81e-38

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 136.52  E-value: 1.81e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR---N 81
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITK----LPMHKRarlG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:cd03218   77 IGYLPQEASIFRKLTVEENILAVLEirGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 160 LDEPFSNIDTQVRHElISQIRKIFKKQGVtAIFVT-HSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSK 231
Cdd:cd03218  157 LDEPFAGVDPIAVQD-IQKIIKILKDRGI-GVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELVR 227
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 5-215 2.00e-38

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 135.81  E-value: 2.00e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDDGDNWLPPEQ--RNI 82
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSG------EITFDGKSYQKNIEalRRI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLTVNQNvgFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03268   75 GALIEAPGFYPNLTAREN--LRLLARLLGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDE 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 163 PFSNIDTqvrhELISQIRKIF---KKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03268  153 PTNGLDP----DGIKELRELIlslRDQGITVLISSHLLSEIQKVADRIGIINKGKL 204
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 5-228 2.09e-38

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 143.29  E-value: 2.09e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY----ESQTILESLSLEVEHGEIVCLLGASGCGKT-TLLkAVAGLLPLSSGIMS----LNCQTIDDgdnwL 75
Cdd:COG4172    7 LSVEDLSVAFgqggGTVEAVKGVSFDIAAGETLALVGESGSGKSvTAL-SILRLLPDPAAHPSgsilFDGQDLLG----L 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  76 PPEQ------RNIGMIFQD--YALFPHLTVNQNVGFGL---KDLSDQQKKEKVQEMLELVHLDEFG---DRYPHQLSGGQ 141
Cdd:COG4172   82 SERElrrirgNRIAMIFQEpmTSLNPLHTIGKQIAEVLrlhRGLSGAAARARALELLERVGIPDPErrlDAYPHQLSGGQ 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 142 QQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTH-----SReeafaFADKMAVMNHGVIE 216
Cdd:COG4172  162 RQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHdlgvvRR-----FADRVAVMRQGEIV 236

                        250
                 ....*....|..
gi 490872517 217 QYGSASELYFHP 228
Cdd:COG4172  237 EQGPTAELFAAP 248
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 5-215 2.38e-38

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 134.09  E-value: 2.38e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDdgdNWLPPEQRN--I 82
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVS---FASPRDARRagI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIfqdyalfphltvnqnvgfglkdlsdqqkkekvqemlelvhldefgdrypHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03216   78 AMV-------------------------------------------------YQLSVGERQMVEIARALARNARLLILDE 108

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490872517 163 PFSNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03216  109 PTAALTPAEVERLFKVIRR-LRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 5-219 1.30e-37

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 133.86  E-value: 1.30e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGeIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLppeQRNIGM 84
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKL---RRRIGY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03264   77 LPQEFGVYPNFTVREFLDYiaWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDE 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 163 PFSNIDTQVRHELisqiRKIFKKQGVTAIFV--THSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03264  157 PTAGLDPEERIRF----RNLLSELGEDRIVIlsTHIVEDVESLCNQVAVLNKGKLVFEG 211
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
5-223 2.08e-37

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 134.47  E-value: 2.08e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RNI 82
Cdd:COG4559    2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAA----WSPWElaRRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYAL-FPhLTVNQNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLA------- 152
Cdd:COG4559   78 AVLPQHSSLaFP-FTVEEVVALGRapHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvd 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 153 YKPDLLLLDEPFSNIDtqVRHELIS-QIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:COG4559  157 GGPRWLFLDEPTSALD--LAHQHAVlRLARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEE 226
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 1-239 1.42e-36

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 132.27  E-value: 1.42e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSgIMSLNCQTIDDGDNWLPPE-- 78
Cdd:PRK14267   1 MKFAIETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNE-EARVEGEVRLFGRNIYSPDvd 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 ----QRNIGMIFQDYALFPHLTVNQNVGFGLK--DLSDQQKK--EKVQEMLELVHL-DEFGDR---YPHQLSGGQQQRVA 146
Cdd:PRK14267  80 pievRREVGMVFQYPNPFPHLTIYDNVAIGVKlnGLVKSKKEldERVEWALKKAALwDEVKDRlndYPSNLSGGQRQRLV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 147 IARSLAYKPDLLLLDEPFSNID---TQVRHELISQIRKIFkkqgvTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:PRK14267 160 IARALAMKPKILLMDEPTANIDpvgTAKIEELLFELKKEY-----TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRK 234

                        250
                 ....*....|....*.
gi 490872517 224 LYFHPSSKFVADFLGG 239
Cdd:PRK14267 235 VFENPEHELTEKYVTG 250
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 5-215 2.15e-36

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 129.26  E-value: 2.15e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnWLPPEQR-N 81
Cdd:cd03246    1 LEVENVSFRYpgAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQ---WDPNELGdH 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHlTVNQNVgfglkdlsdqqkkekvqemlelvhldefgdryphqLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:cd03246   78 VGYLPQDDELFSG-SIAENI-----------------------------------LSGGQRQRLGLARALYGNPRILVLD 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 162 EPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHsREEAFAFADKMAVMNHGVI 215
Cdd:cd03246  122 EPNSHLDVEGERALNQAIAAL-KAAGATRIVIAH-RPETLASADRILVLEDGRV 173
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 5-219 2.42e-36

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 130.48  E-value: 2.42e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlppeQRNIGM 84
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAA------RNRIGY 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTV-NQNVGFG-LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03269   75 LPEERGLYPKMKViDQLVYLAqLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDE 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 163 PFSNIDTqVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03269  155 PFSGLDP-VNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 20-215 3.01e-36

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 130.57  E-value: 3.01e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGDNWLPPEQ--RNIGMIFQDYALFPHLTV 97
Cdd:cd03266   21 VDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFA-----TVDGFDVVKEPAEarRRLGFVSDSTGLYDRLTA 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  98 NQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHEL 175
Cdd:cd03266   96 RENLEYfaGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRAL 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 490872517 176 ISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03266  176 REFIRQL-RALGKCILFSTHIMQEVERLCDRVVVLHRGRV 214
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 5-228 3.93e-36

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 130.53  E-value: 3.93e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR---N 81
Cdd:COG1137    4 LEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITH----LPMHKRarlG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHLTVNQNVG--FGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:COG1137   80 IGYLPQEASIFRKLTVEDNILavLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFIL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 160 LDEPFSNID--TqvrhelISQIRKIF---KKQGVtAIFVT-HSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:COG1137  160 LDEPFAGVDpiA------VADIQKIIrhlKERGI-GVLITdHNVRETLGICDRAYIISEGKVLAEGTPEEILNNP 227
cbiO PRK13641
energy-coupling factor transporter ATPase;
20-240 8.04e-36

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 131.49  E-value: 8.04e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTI--DDGDNWLPPEQRNIGMIFQ--DYALFPHl 95
Cdd:PRK13641  23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpETGNKNLKKLRKKVSLVFQfpEAQLFEN- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  96 TVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR 172
Cdd:PRK13641 102 TVLKDVEFGPKNFgfSEDEAKEKALKWLKKVGLSEdLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGR 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 173 HELIsQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP------------SSKFVADFLGGG 240
Cdd:PRK13641 182 KEMM-QLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKewlkkhyldepaTSRFASKLEKGG 260
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 4-210 1.34e-35

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 135.49  E-value: 1.34e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    4 ALSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDG--DNWlppeQR 80
Cdd:TIGR02857 321 SLEFSGVSVAYPGRRpALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADAdaDSW----RD 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFQDYALFPHlTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEF------------GDRyPHQLSGGQQQRVAIA 148
Cdd:TIGR02857 397 QIAWVPQHPFLFAG-TIAENIRLARPDASD----AEIREALERAGLDEFvaalpqgldtpiGEG-GAGLSGGQAQRLALA 470

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517  149 RSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFkkQGVTAIFVTHSREEAfAFADKMAVM 210
Cdd:TIGR02857 471 RAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALA--QGRTVLLVTHRLALA-ALADRIVVL 529
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
20-210 1.41e-35

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 134.76  E-value: 1.41e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlpP---EQRNIGMIFQDYALFPHLT 96
Cdd:COG1129   20 LDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRS----PrdaQAAGIAIIHQELNLVPNLS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  97 VNQNV-------GFGLkdLSDQQKKEKVQEMLELVHLDEfgDryPHQ----LSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:COG1129   96 VAENIflgreprRGGL--IDWRAMRRRARELLARLGLDI--D--PDTpvgdLSVAQQQLVEIARALSRDARVLILDEPTA 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 490872517 166 NI-DTQVRHeLISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVM 210
Cdd:COG1129  170 SLtEREVER-LFRIIRR-LKAQGVAIIYISHRLDEVFEIADRVTVL 213
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 15-223 2.11e-35

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 135.26  E-value: 2.11e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  15 ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLncqtidDG---DNWlPPEQ--RNIGMIFQDY 89
Cdd:COG4618  343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRL------DGadlSQW-DREElgRHIGYLPQDV 415

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  90 ALFPHlTVNQNVG-FGlkDLSDqqkkEKVQEMLELVHLDEFGDRYP-----------HQLSGGQQQRVAIARSLAYKPDL 157
Cdd:COG4618  416 ELFDG-TIAENIArFG--DADP----EKVVAAAKLAGVHEMILRLPdgydtrigeggARLSGGQRQRIGLARALYGDPRL 488

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:COG4618  489 VVLDEPNSNLDDEGEAALAAAIRAL-KARGATVVVITH-RPSLLAAVDKLLVLRDGRVQAFGPRDE 552
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 5-225 1.48e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 127.50  E-value: 1.48e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQRNIG 83
Cdd:PRK13639   2 LETRDLKYSYPDGTeALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKKSLLEVRKTVG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQ--DYALF-PhlTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:PRK13639  82 IVFQnpDDQLFaP--TVEEDVAFGPLNlgLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEII 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 159 LLDEPFSNIDTQVrhelISQIRKIFK---KQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13639 160 VLDEPTSGLDPMG----ASQIMKLLYdlnKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVF 225
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 5-225 1.68e-34

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 126.19  E-value: 1.68e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT--ILESLSLEVEHGEIVCLLGASGCGKTTLLKavagLLP----LSSGIMSLNCQTIDDGDnwLPPE 78
Cdd:cd03251    1 VEFKNVTFRYPGDGppVLRDISLDIPAGETVALVGPSGSGKSTLVN----LIPrfydVDSGRILIDGHDVRDYT--LASL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFpHLTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAI 147
Cdd:cd03251   75 RRQIGLVSQDVFLF-NDTVAENIAYGRPGATR----EEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAI 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:cd03251  150 ARALLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAH-RLSTIENADRIVVLEDGKIVERGTHEELL 224
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 24-229 1.83e-34

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 128.67  E-value: 1.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  24 SLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMSLNCQTIDDGDNWLPPEQRNIGMIFQD--YALFPHLTVNQN 100
Cdd:PRK15079  41 TLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGeVAWLGKDLLGMKDDEWRAVRSDIQMIFQDplASLNPRMTIGEI 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 101 VGFGLK----DLSDQQKKEKVQEMLELVHL-DEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHEL 175
Cdd:PRK15079 121 IAEPLRtyhpKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQV 200

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 176 ISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPS 229
Cdd:PRK15079 201 VNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPL 254
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 5-228 3.30e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 128.04  E-value: 3.30e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT-----ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSL----NCQTIDDGDNWL 75
Cdd:PRK13631  22 LRVKNLYCVFDEKQenelvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyIGDKKNNHELIT 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  76 PPEQRNI----------GMIFQ--DYALFPHlTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGG 140
Cdd:PRK13631 102 NPYSKKIknfkelrrrvSMVFQfpEYQLFKD-TIEKDIMFGPVALgvKKSEAKKLAKFYLNKMGLDDsYLERSPFGLSGG 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 141 QQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELIsQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGS 220
Cdd:PRK13631 181 QKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMM-QLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGT 259


                 ....*...
gi 490872517 221 ASELYFHP 228
Cdd:PRK13631 260 PYEIFTDQ 267
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 5-240 5.25e-34

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 125.39  E-value: 5.25e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGDNWLPP----EQR 80
Cdd:PRK10895   4 LTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNI-----IIDDEDISLLPlharARR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPHLTVNQNVGFGL---KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:PRK10895  79 GIGYLPQEASIFRRLSVYDNLMAVLqirDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKF 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 158 LLLDEPFSNIDTqvrhelIS--QIRKI---FKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKF 232
Cdd:PRK10895 159 ILLDEPFAGVDP------ISviDIKRIiehLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKR 232


                 ....*...
gi 490872517 233 VadFLGGG 240
Cdd:PRK10895 233 V--YLGED 238
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-224 1.47e-33

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 125.61  E-value: 1.47e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlppeQRNIG 83
Cdd:COG4152    1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPED------RRRIG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 mifqdY-----ALFPHLTV-NQNVGFG-LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPD 156
Cdd:COG4152   75 -----YlpeerGLYPKMKVgEQLVYLArLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPE 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 157 LLLLDEPFSNIDTqVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG4152  150 LLILDEPFSGLDP-VNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI 216
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 5-239 1.62e-33

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 124.12  E-value: 1.62e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGImSLNCQTIDDGDNWLPPE------ 78
Cdd:PRK14239   6 LQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNPEV-TITGSIVYNGHNIYSPRtdtvdl 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFPhLTVNQNVGFGL--KDLSDQQK-KEKVQEMLELVHL-DEFGDRYpHQ----LSGGQQQRVAIARS 150
Cdd:PRK14239  85 RKEIGMVFQQPNPFP-MSIYENVVYGLrlKGIKDKQVlDEAVEKSLKGASIwDEVKDRL-HDsalgLSGGQQQRVCIARV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 151 LAYKPDLLLLDEPFSNIDTqvrhelISQiRKIFK-----KQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK14239 163 LATSPKIILLDEPTSALDP------ISA-GKIEEtllglKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMF 235

                        250
                 ....*....|....
gi 490872517 226 FHPSSKFVADFLGG 239
Cdd:PRK14239 236 MNPKHKETEDYISG 249
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 6-224 3.09e-33

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 123.27  E-value: 3.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RNIG 83
Cdd:COG4604    3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVAT----TPSRElaKRLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFG--------LKdlsdQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKP 155
Cdd:COG4604   79 ILRQENHINSRLTVRELVAFGrfpyskgrLT----AEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDT 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 156 DLLLLDEPFSNIDtqVRH--ELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG4604  155 DYVLLDEPLNNLD--MKHsvQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 8-230 7.24e-33

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 122.94  E-value: 7.24e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYESQT--ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNIGMI 85
Cdd:PRK13648  11 KNVSFQYQSDAsfTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDN--FEKLRKHIGIV 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  86 FQD-YALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:PRK13648  89 FQNpDNQFVGSIVKYDVAFGLENhaVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDE 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQYGSASELYFHPSS 230
Cdd:PRK13648 169 ATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEA-MEADHVIVMNKGTVYKEGTPTEIFDHAEE 235
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 8-224 1.54e-32

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 121.18  E-value: 1.54e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYE-SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNIGMIF 86
Cdd:cd03253    4 ENVTFAYDpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVT--LDSLRRAIGVVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  87 QDYALFpHLTVNQNVGFGLKDLSDQQkkekVQEMLELVHLDEFGDRYPHQ-----------LSGGQQQRVAIARSLAYKP 155
Cdd:cd03253   82 QDTVLF-NDTIGYNIRYGRPDATDEE----VIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIARAILKNP 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 156 DLLLLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03253  157 PILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAH-RLSTIVNADKIIVLKDGRIVERGTHEEL 222
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 5-242 2.17e-32

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 121.17  E-value: 2.17e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS-----SGIMSLNCQTIDDGDnwLPPEQ 79
Cdd:PRK14247   4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYpearvSGEVYLDGQDIFKMD--VIELR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFPHLTVNQNVGFGLK----DLSDQQKKEKVQEMLELVHL-DEFGDRY---PHQLSGGQQQRVAIARSL 151
Cdd:PRK14247  82 RRVQMVFQIPNPIPNLSIFENVALGLKlnrlVKSKKELQERVRWALEKAQLwDEVKDRLdapAGKLSGGQQQRLCIARAL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 152 AYKPDLLLLDEPFSNIDTqvrhELISQIRKIF--KKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPS 229
Cdd:PRK14247 162 AFQPEVLLADEPTANLDP----ENTAKIESLFleLKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPR 237

                        250
                 ....*....|...
gi 490872517 230 SKFVADFLGGGSY 242
Cdd:PRK14247 238 HELTEKYVTGRLY 250
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
5-223 2.63e-32

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 120.89  E-value: 2.63e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RNI 82
Cdd:PRK11231   3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISM----LSSRQlaRRL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLTVNQNVGFGLK-------DLSdQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKP 155
Cdd:PRK11231  79 ALLPQHHLTPEGITVRELVAYGRSpwlslwgRLS-AEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDT 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 156 DLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:PRK11231 158 PVVLLDEPTTYLDINHQVELMRLMREL-NTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEE 224
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 1-213 5.32e-32

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 125.14  E-value: 5.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlpPEQ- 79
Cdd:COG3845    2 MPPALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRS----PRDa 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 --RNIGMIFQDYALFPHLTVNQNVGFGLKD-----LSDQQKKEKVQEMLElvhldEFG-----DRYPHQLSGGQQQRVAI 147
Cdd:COG3845   78 iaLGIGMVHQHFMLVPNLTVAENIVLGLEPtkggrLDRKAARARIRELSE-----RYGldvdpDAKVEDLSVGEQQRVEI 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:COG3845  153 LKALYRGARILILDEPTAVLTPQEADELFEILRR-LAAEGKSIIFITHKLREVMAIADRVTVLRRG 217
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 20-228 8.23e-32

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 121.61  E-value: 8.23e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLncqtidDGDNWLPPE-------QRNIGMIFQD-YA- 90
Cdd:PRK11308  31 LDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYY------QGQDLLKADpeaqkllRQKIQIVFQNpYGs 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  91 LFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:PRK11308 105 LNPRKKVGQILEEPLLintSLSAAERREKALAMMAKVGLRpEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSA 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 167 IDTQVRheliSQIRKIF----KKQGVTAIFVTHSREEAFAFADKMAVMNHG-VIEQyGSASELYFHP 228
Cdd:PRK11308 185 LDVSVQ----AQVLNLMmdlqQELGLSYVFISHDLSVVEHIADEVMVMYLGrCVEK-GTKEQIFNNP 246
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 5-228 9.87e-32

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 120.29  E-value: 9.87e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYE-SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNIG 83
Cdd:PRK13652   4 IETRDLCYSYSgSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKEN--IREVRKFVG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQ--DYALFPHlTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:PRK13652  82 LVFQnpDDQIFSP-TVEQDIAFGPINlgLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK13652 161 LDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 18-200 1.11e-31

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 118.73  E-value: 1.11e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  18 TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNwlppEQR------NIGMIFQDYAL 91
Cdd:PRK10584  24 SILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDE----EARaklrakHVGFVFQSFML 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  92 FPHLTVNQNVGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDT 169
Cdd:PRK10584 100 IPTLNALENVELPalLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDR 179

                        170       180       190
                 ....*....|....*....|....*....|.
gi 490872517 170 QVRHELISQIRKIFKKQGVTAIFVTHSREEA 200
Cdd:PRK10584 180 QTGDKIADLLFSLNREHGTTLILVTHDLQLA 210
cbiO PRK13642
energy-coupling factor transporter ATPase;
1-225 2.58e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 119.04  E-value: 2.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQT---ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWlpP 77
Cdd:PRK13642   1 MNKILEVENLVFKYEKESdvnQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVW--N 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  78 EQRNIGMIFQDY-ALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:PRK13642  79 LRRKIGMVFQNPdNQFVGATVEDDVAFGMENqgIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALR 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13642 159 PEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEIIKEAAPSELF 228
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 5-239 3.07e-31

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 118.23  E-value: 3.07e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPE----QR 80
Cdd:PRK14246  11 FNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIFQIDaiklRK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPHLTVNQNVGFGLKDLSDQQKKEK---VQEMLELVHL-DEFGDRY---PHQLSGGQQQRVAIARSLAY 153
Cdd:PRK14246  91 EVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIkkiVEECLRKVGLwKEVYDRLnspASQLSGGQQQRLTIARALAL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 154 KPDLLLLDEPFSNID---TQVRHELISQIrkifkKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSS 230
Cdd:PRK14246 171 KPKVLLMDEPTSMIDivnSQAIEKLITEL-----KNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKN 245


                 ....*....
gi 490872517 231 KFVADFLGG 239
Cdd:PRK14246 246 ELTEKYVIG 254
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
7-239 3.27e-31

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 118.71  E-value: 3.27e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDDGDNwLPPEQRN----- 81
Cdd:PRK11831  10 MRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHG------EILFDGEN-IPAMSRSrlytv 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 ---IGMIFQDYALFPHLTVNQNVGFGLKD---LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKP 155
Cdd:PRK11831  83 rkrMSMLFQSGALFTDMNVFDNVAYPLREhtqLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 156 DLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKfVAD 235
Cdd:PRK11831 163 DLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPDPR-VRQ 241


                 ....
gi 490872517 236 FLGG 239
Cdd:PRK11831 242 FLDG 245
cbiO PRK13645
energy-coupling factor transporter ATPase;
20-225 7.32e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 118.19  E-value: 7.32e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDdGDNWLPPE----------QRNIGMIFQ-- 87
Cdd:PRK13645  27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETG------QTIV-GDYAIPANlkkikevkrlRKEIGLVFQfp 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  88 DYALFPHlTVNQNVGFGLKDLSD--QQKKEKVQEMLELVHL-DEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:PRK13645 100 EYQLFQE-TIEKDIAFGPVNLGEnkQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPT 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 165 SNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13645 179 GGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-213 7.62e-31

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 114.84  E-value: 7.62e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYEsqtiLESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQRNIG 83
Cdd:cd03215    4 VLEVRGLSVKGA----VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRS---PRDAIRAG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIF-----QDYALFPHLTVNQNVGFglkdlsdqqkkekvqemlelvhldefgdryPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:cd03215   77 IAYvpedrKREGLVLDLSVAENIAL------------------------------SSLLSGGNQQKVVLARWLARDPRVL 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:cd03215  127 ILDEPTRGVDVGAKAEIYRLIRE-LADAGKAVLLISSELDELLGLCDRILVMYEG 180
cbiO PRK13640
energy-coupling factor transporter ATPase;
4-225 8.42e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 117.98  E-value: 8.42e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYES--QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAG-LLPLSSGIMSLNCQTIDDGDNWLPPEQR 80
Cdd:PRK13640   5 IVEFKHVSFTYPDskKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlLLPDDNPNSKITVDGITLTAKTVWDIRE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDY-ALFPHLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:PRK13640  85 KVGIVFQNPdNQFVGATVGDDVAFGLENraVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKI 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAfAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13640 165 IILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIF 231
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 8-215 9.69e-31

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 122.67  E-value: 9.69e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    8 KDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGD-NWLPPE--QRNI 82
Cdd:TIGR03375 467 RNVSFAYpgQETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSV-----LLDGVDiRQIDPAdlRRNI 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   83 GMIFQDYALFpHLTVNQNVGFGLKDLSDQQkkekVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSL 151
Cdd:TIGR03375 542 GYVPQDPRLF-YGTLRDNIALGAPYADDEE----ILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARAL 616

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517  152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQgvTAIFVTHsREEAFAFADKMAVMNHGVI 215
Cdd:TIGR03375 617 LRDPPILLLDEPTSAMDNRSEERFKDRLKRWLAGK--TLVLVTH-RTSLLDLVDRIIVMDNGRI 677
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 7-225 1.01e-30

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 116.48  E-value: 1.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYES---QTILESLSLEVEHGEIVCLLGASGCGKTTllkaVAGLL-----PLSSGImslncqTIDDGD------ 72
Cdd:cd03249    3 FKNVSFRYPSrpdVPILKGLSLTIPPGKTVALVGSSGCGKST----VVSLLerfydPTSGEI------LLDGVDirdlnl 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  73 NWLppeQRNIGMIFQDYALFPhLTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQ 141
Cdd:cd03249   73 RWL---RSQIGLVSQEPVLFD-GTIAENIRYGKPDATD----EEVEEAAKKANIHDFIMSLPDgydtlvgergsQLSGGQ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 142 QQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfkKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSA 221
Cdd:cd03249  145 KQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRA--MKGRTTIVIAH-RLSTIRNADLIAVLQNGQVVEQGTH 221


                 ....
gi 490872517 222 SELY 225
Cdd:cd03249  222 DELM 225
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 20-224 2.20e-30

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 120.68  E-value: 2.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCqtiddGDNWL------PPEQ----RNIGMIFQDY 89
Cdd:TIGR03269 300 VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRV-----GDEWVdmtkpgPDGRgrakRYIGILHQEY 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   90 ALFPHLTVNQNV--GFGLkDLSDQQKKEKVQEMLELVHLDE-----FGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:TIGR03269 375 DLYPHRTVLDNLteAIGL-ELPDELARMKAVITLKMVGFDEekaeeILDKYPDELSEGERHRVALAQVLIKEPRIVILDE 453

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517  163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:TIGR03269 454 PTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 15-224 2.20e-30

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 120.92  E-value: 2.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   15 ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlpPEQ--RNIGMIFQDYALF 92
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWD----RETfgKHIGYLPQDVELF 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   93 PHlTVNQNVG-FGlkdlsDQQKKEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:TIGR01842 405 PG-TVAENIArFG-----ENADPEKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVL 478

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517  161 DEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:TIGR01842 479 DEPNSNLDEEGEQALANAIKAL-KARGITVVVITH-RPSLLGCVDKILVLQDGRIARFGERDEV 540
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 8-215 2.98e-30

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 114.61  E-value: 2.98e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYESQTI--LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSlncqtIDDGDNW-LPPE--QRNI 82
Cdd:cd03245    6 RNVSFSYPNQEIpaLDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVL-----LDGTDIRqLDPAdlRRNI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFpHLTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSL 151
Cdd:cd03245   81 GYVPQDVTLF-YGTLRDNITLGAPLADD----ERILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARAL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVI 215
Cdd:cd03245  156 LNDPPILLLDEPTSAMDMNSEERLKERLRQLLG--DKTLIIITH-RPSLLDLVDRIIVMDSGRI 216
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 18-237 3.65e-30

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 120.20  E-value: 3.65e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  18 TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlSSGIMSLNCQTIDdgdNW----LPPEQRNIGMIFQD--YAL 91
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLIN-SQGEIWFDGQPLH---NLnrrqLLPVRHRIQVVFQDpnSSL 375

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  92 FPHLTVNQNVGFGL----KDLSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:PRK15134 376 NPRLNVLQIIEEGLrvhqPTLSAAQREQQVIAVMEEVGLDpETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSS 455

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 167 IDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG-VIEQyGSASELYFHPSSKFVADFL 237
Cdd:PRK15134 456 LDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGeVVEQ-GDCERVFAAPQQEYTRQLL 526
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1-195 4.20e-30

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 120.60  E-value: 4.20e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKY----ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTID--DGDNW 74
Cdd:PRK10535   1 MTALLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVAtlDADAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  75 LPPEQRNIGMIFQDYALFPHLTVNQNV-------GFGLKdlsdqQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAI 147
Cdd:PRK10535  81 AQLRREHFGFIFQRYHLLSHLTAAQNVevpavyaGLERK-----QRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSI 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVRHELISqIRKIFKKQGVTAIFVTH 195
Cdd:PRK10535 156 ARALMNGGQVILADEPTGALDSHSGEEVMA-ILHQLRDRGHTVIIVTH 202
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 1-224 6.30e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 115.22  E-value: 6.30e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGL-LPLSSGIMSLNCQTIDDGDNWLppe 78
Cdd:PRK13647   1 MDNIIEVEDLHFRYKDGTkALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIyLPQRGRVKVMGREVNAENEKWV--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDY--ALFPhLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:PRK13647  78 RSKVGLVFQDPddQVFS-STVWDDVAFGPVNmgLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMD 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISqIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK13647 157 PDVIVLDEPMAYLDPRGQETLME-ILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLL 225
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
14-200 1.53e-29

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 111.94  E-value: 1.53e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  14 YESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDGDNwlppeqRNIGMIFQDYAL-- 91
Cdd:NF040873   2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSG-------TVRRAGG------ARVAYVPQRSEVpd 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  92 -FPhLTVNQNVGFG-------LKDLSDQQKKEkVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:NF040873  69 sLP-LTVRDLVAMGrwarrglWRRLTRDDRAA-VDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEP 146

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 490872517 164 FSNIDTQVR---HELISQIRkifkKQGVTAIFVTHSREEA 200
Cdd:NF040873 147 TTGLDAESReriIALLAEEH----ARGATVVVVTHDLELV 182
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 5-195 1.63e-29

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 112.07  E-value: 1.63e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQRNIGM 84
Cdd:TIGR01189   1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQR---DEPHENILY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   85 IFQDYALFPHLTVNQNVGFGLKDLSDQQKKekVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:TIGR01189  78 LGHLPGLKPELSALENLHFWAAIHGGAQRT--IEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPT 155

                         170       180       190
                  ....*....|....*....|....*....|.
gi 490872517  165 SNIDTQVRHELISQIRKIFKKQGVtAIFVTH 195
Cdd:TIGR01189 156 TALDKAGVALLAGLLRAHLARGGI-VLLTTH 185
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 4-206 1.76e-29

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 118.37  E-value: 1.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLT-CKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDdgdnwLPPEQRni 82
Cdd:COG4178  362 ALALEDLTlRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSG-------RIA-----RPAGAR-- 427

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 gMIF--Q----------DYALFPHLTvnqnvgfglKDLSDQQkkekVQEMLELVHLDEFGDRY------PHQLSGGQQQR 144
Cdd:COG4178  428 -VLFlpQrpylplgtlrEALLYPATA---------EAFSDAE----LREALEAVGLGHLAERLdeeadwDQVLSLGEQQR 493

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 145 VAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADK 206
Cdd:COG4178  494 LAFARLLLHKPDWLFLDEATSALDEENEAALYQLLREELP--GTTVISVGH-RSTLAAFHDR 552
cbiO PRK13646
energy-coupling factor transporter ATPase;
14-225 3.20e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 113.72  E-value: 3.20e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  14 YESQTIlESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTI--DDGDNWLPPEQRNIGMIFQ--DY 89
Cdd:PRK13646  18 YEHQAI-HDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITIthKTKDKYIRPVRKRIGMVFQfpES 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  90 ALFPHlTVNQNVGFGLKDLS---DQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:PRK13646  97 QLFED-TVEREIIFGPKNFKmnlDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAG 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 167 IDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13646 176 LDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELF 234
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 13-224 3.69e-29

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 112.19  E-value: 3.69e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  13 KYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG---IMSLNCQTIDDgdNWLppeQRNIGMIFQDY 89
Cdd:cd03252   11 KPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGrvlVDGHDLALADP--AWL---RRQVGVVLQEN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  90 ALFpHLTVNQNVGFGLKDLSdqqkKEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSLAYKPDLL 158
Cdd:cd03252   86 VLF-NRSIRDNIALADPGMS----MERVIEAAKLAGAHDFISELPEgydtivgeqgaGLSGGQRQRIAIARALIHNPRIL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03252  161 IFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAH-RLSTVKNADRIIVMEKGRIVEQGSHDEL 223
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 5-196 4.46e-29

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 117.08  E-value: 4.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYE-SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGDNWLPPE---QR 80
Cdd:TIGR02868 335 LELRDLSAGYPgAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEV-----TLDGVPVSSLDQdevRR 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFQDYALFpHLTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIAR 149
Cdd:TIGR02868 410 RVSVCAQDAHLF-DTTVRENLRLARPDATD----EELWAALERVGLADWLRALPDgldtvlgeggaRLSGGERQRLALAR 484

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 490872517  150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfkKQGVTAIFVTHS 196
Cdd:TIGR02868 485 ALLADAPILLLDEPTEHLDAETADELLEDLLAA--LSGRTVVLITHH 529
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 19-215 6.47e-29

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 111.21  E-value: 6.47e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLP---LSSGIMSLNCQTIDDgDNWlppeQRNIGMIFQDYALFPHL 95
Cdd:cd03234   22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILFNGQPRKP-DQF----QKCVAYVRQDDILLPGL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  96 TVNQNVGFGL-----KDLSDQQKKEKV-QEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDT 169
Cdd:cd03234   97 TVRETLTYTAilrlpRKSSDAIRKKRVeDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDS 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 490872517 170 QVRHELISQIRKIFKKqGVTAIFVTHS-REEAFAFADKMAVMNHGVI 215
Cdd:cd03234  177 FTALNLVSTLSQLARR-NRIVILTIHQpRSDLFRLFDRILLLSSGEI 222
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 4-237 9.49e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 111.67  E-value: 9.49e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSS-----GIMSLNCQTIDDGDNWLPPE 78
Cdd:PRK14258   7 AIKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIYERRVNLNRL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFPhLTVNQNVGFGLKdLSDQQKKEKVQEMLELVHLD-EFGDRYPHQ-------LSGGQQQRVAIARS 150
Cdd:PRK14258  87 RRQVSMVHPKPNLFP-MSVYDNVAYGVK-IVGWRPKLEIDDIVESALKDaDLWDEIKHKihksaldLSGGQQQRLCIARA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 151 LAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVM--NHGVIEQ---YGSASELY 225
Cdd:PRK14258 165 LAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFkgNENRIGQlveFGLTKKIF 244

                        250
                 ....*....|..
gi 490872517 226 FHPSSKFVADFL 237
Cdd:PRK14258 245 NSPHDSRTREYV 256
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 5-224 1.02e-28

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 116.48  E-value: 1.02e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLT-CKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSsGIMSLNCQTIDDgdnwLPPEQ--RN 81
Cdd:PRK11174 350 IEAEDLEiLSPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQ-GSLKINGIELRE----LDPESwrKH 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFpHLTVNQNVGFGLKDLSDQQkkekVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARS 150
Cdd:PRK11174 425 LSWVGQNPQLP-HGTLRDNVLLGNPDASDEQ----LQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARA 499

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 151 LAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQgvTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK11174 500 LLQPCQLLLLDEPTASLDAHSEQLVMQALNAASRRQ--TTLMVTH-QLEDLAQWDQIWVMQDGQIVQQGDYAEL 570
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
1-213 2.65e-28

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 111.82  E-value: 2.65e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCA-LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGdnwLPPEQ 79
Cdd:PRK13537   3 MSVApIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSR---ARHAR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFPHLTVNQNVG-----FGLkdlSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:PRK13537  80 QRVGVVPQFDNLDPDFTVRENLLvfgryFGL---SAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVND 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKIFKKqGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK13537 157 PDVLVLDEPTTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEG 214
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 5-225 3.39e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 110.71  E-value: 3.39e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT-ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQRNIG 83
Cdd:PRK13636   6 LKVEELNYNYSDGThALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRKGLMKLRESVG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQ--DYALFPhLTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:PRK13636  86 MVFQdpDNQLFS-ASVYQDVSFGAVNlkLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLV 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13636 165 LDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
cbiO PRK13649
energy-coupling factor transporter ATPase;
4-225 5.17e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 110.22  E-value: 5.17e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILES-----LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTI--DDGDNWLP 76
Cdd:PRK13649   2 GINLQNVSYTYQAGTPFEGralfdVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLItsTSKNKDIK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 PEQRNIGMIFQ--DYALFPHlTVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGGQQQRVAIARSL 151
Cdd:PRK13649  82 QIRKKVGLVFQfpESQLFEE-TVLKDVAFGPQNfgVSQEEAEALAREKLALVGISEsLFEKNPFELSGGQMRRVAIAGIL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHELISqirkIFKK---QGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13649 161 AMEPKILVLDEPTAGLDPKGRKELMT----LFKKlhqSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 20-228 7.97e-28

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 114.18  E-value: 7.97e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDD-GDNWLPPEQRNIGMIFQD-YA-LFPHLT 96
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTlSPGKLQALRRDIQFIFQDpYAsLDPRQT 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  97 VNQNVGFGLKD---LSDQQKKEKVQEMLELVHL-DEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR 172
Cdd:PRK10261 420 VGDSIMEPLRVhglLPGKAAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIR 499

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 173 HELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK10261 500 GQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENP 555
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 5-213 8.73e-28

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 107.56  E-value: 8.73e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQ-----TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLN------CQTiddgdN 73
Cdd:cd03250    1 ISVEDASFTWDSGeqetsFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPgsiayvSQE-----P 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  74 WLPPEqrnigmifqdyalfphlTVNQNVGFGLKdlSDQQKKEKVqemLELVHLDEFGDRYPHQ-----------LSGGQQ 142
Cdd:cd03250   76 WIQNG-----------------TIRENILFGKP--FDEERYEKV---IKACALEPDLEILPDGdlteigekginLSGGQK 133

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 143 QRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQ-IRKIFKKqGVTAIFVTHsREEAFAFADKMAVMNHG 213
Cdd:cd03250  134 QRISLARAVYSDADIYLLDDPLSAVDAHVGRHIFENcILGLLLN-NKTRILVTH-QLQLLPHADQIVVLDNG 203
cbiO PRK13643
energy-coupling factor transporter ATPase;
20-225 1.45e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 109.44  E-value: 1.45e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLN--CQTIDDGDNWLPPEQRNIGMIFQ--DYALFPHl 95
Cdd:PRK13643  22 LFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGdiVVSSTSKQKEIKPVRKKVGVVFQfpESQLFEE- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  96 TVNQNVGFGLKD--LSDQQKKEKVQEMLELVHLD-EFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR 172
Cdd:PRK13643 101 TVLKDVAFGPQNfgIPKEKAEKIAAEKLEMVGLAdEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKAR 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490872517 173 HELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13643 181 IEMMQLFESI-HQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 5-219 1.67e-27

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 107.23  E-value: 1.67e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIddgdnWLPpeqrNIGM 84
Cdd:cd03220   23 LGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVS-----SLL----GLGG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQdyalfPHLTVNQNVGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03220   94 GFN-----PELTGRENIYLNgrLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDE 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 163 PFSNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03220  169 VLAVGDAAFQEKCQRRLRE-LLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
5-225 2.42e-27

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 108.17  E-value: 2.42e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQRNIGM 84
Cdd:PRK13638   2 LATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLALRQQVAT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQD--YALFpHLTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:PRK13638  82 VFQDpeQQIF-YTDIDSDIAFSLRNLgvPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIFkKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PRK13638 161 DEPTAGLDPAGRTQMIAIIRRIV-AQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 5-215 2.46e-27

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 107.86  E-value: 2.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILE-----SLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMslncqtIDDGD-NWLPP 77
Cdd:COG1101    2 LELKNLSKTFNPGTVNEkraldGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGsIL------IDGKDvTKLPE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  78 EQR--NIGMIFQDYAL--FPHLTVNQNV--------GFGLKDLSDQQKKEKVQEMLELVHL-------DEFGdryphQLS 138
Cdd:COG1101   76 YKRakYIGRVFQDPMMgtAPSMTIEENLalayrrgkRRGLRRGLTKKRRELFRELLATLGLglenrldTKVG-----LLS 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 139 GGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQvRHELISQI-RKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:COG1101  151 GGQRQALSLLMATLTKPKLLLLDEHTAALDPK-TAALVLELtEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRI 227
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 7-215 2.87e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 108.63  E-value: 2.87e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQT-----ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPE--- 78
Cdd:PRK13651   5 VKNIVKIFNKKLptelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEkvl 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 -------------------QRNIGMIFQ--DYALFPHlTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDE-FGDRYP 134
Cdd:PRK13651  85 eklviqktrfkkikkikeiRRRVGVVFQfaEYQLFEQ-TIEKDIIFGPVSMgvSKEEAKKRAAKYIELVGLDEsYLQRSP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 135 HQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHElisqIRKIFK---KQGVTAIFVTHSREEAFAFADKMAVMN 211
Cdd:PRK13651 164 FELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKE----ILEIFDnlnKQGKTIILVTHDLDNVLEWTKRTIFFK 239


                 ....
gi 490872517 212 HGVI 215
Cdd:PRK13651 240 DGKI 243
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
19-195 4.38e-27

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 106.44  E-value: 4.38e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQRN--IGMIFQDYALFPHLT 96
Cdd:PRK11629  24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNqkLGFIYQFHHLLPDFT 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  97 VNQNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHE 174
Cdd:PRK11629 104 ALENVAMPLliGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADS 183

                        170       180
                 ....*....|....*....|.
gi 490872517 175 LISQIRKIFKKQGVTAIFVTH 195
Cdd:PRK11629 184 IFQLLGELNRLQGTAFLVVTH 204
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
20-195 5.40e-27

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 106.11  E-value: 5.40e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNW-LPPEQRNIGMIFQDYALFPHLTVN 98
Cdd:PRK10908  18 LQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNReVPFLRRQIGMIFQDHHLLMDRTVY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  99 QNVGFGL--KDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRhELI 176
Cdd:PRK10908  98 DNVAIPLiiAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALS-EGI 176

                        170
                 ....*....|....*....
gi 490872517 177 SQIRKIFKKQGVTAIFVTH 195
Cdd:PRK10908 177 LRLFEEFNRVGVTVLMATH 195
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 5-195 7.29e-27

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 105.27  E-value: 7.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQRNIGM 84
Cdd:cd03231    1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQR---DSIARGLLY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKDLSDQQkkekVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:cd03231   78 LGHAPGIKTTLSVLENLRFWHADHSDEQ----VEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPT 153

                        170       180       190
                 ....*....|....*....|....*....|.
gi 490872517 165 SNIDTQVRHELISQIRKiFKKQGVTAIFVTH 195
Cdd:cd03231  154 TALDKAGVARFAEAMAG-HCARGGMVVLTTH 183
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4-215 8.14e-27

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 110.49  E-value: 8.14e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYEsqtiLESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPE--QRN 81
Cdd:COG1129  256 VLEVEGLSVGGV----VRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRS---PRDaiRAG 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQD---YALFPHLTVNQNV---------GFGLkdLSDQQKKEKVQEMLELVHLdefgdRYPH------QLSGGQQQ 143
Cdd:COG1129  329 IAYVPEDrkgEGLVLDLSIRENItlasldrlsRGGL--LDRRRERALAEEYIKRLRI-----KTPSpeqpvgNLSGGNQQ 401

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 144 RVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:COG1129  402 KVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRE-LAAEGKAVIVISSELPELLGLSDRILVMREGRI 472
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
20-228 8.60e-27

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 106.80  E-value: 8.60e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnWLPPEQRnIGMIFQD--YALFPHLTV 97
Cdd:PRK15112  29 VKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGD-YSYRSQR-IRMIFQDpsTSLNPRQRI 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  98 NQNVGFGLK---DLSDQQKKEKVQEMLELVHL-DEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRH 173
Cdd:PRK15112 107 SQILDFPLRlntDLEPEQREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRS 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 174 ELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK15112 187 QLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASP 241
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 5-213 1.82e-26

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 103.78  E-value: 1.82e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYES------QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLL--PLSSGIMSLNCQTIDDgDNWlp 76
Cdd:cd03213    4 LSFRNLTVTVKSspsksgKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRtgLGVSGEVLINGRPLDK-RSF-- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 peQRNIGMIFQDYALFPHLTVNQNVGFGLKdLSdqqkkekvqemlelvhldefgdryphQLSGGQQQRVAIARSLAYKPD 156
Cdd:cd03213   81 --RKIIGYVPQDDILHPTLTVRETLMFAAK-LR--------------------------GLSGGERKRVSIALELVSNPS 131

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 157 LLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHS-REEAFAFADKMAVMNHG 213
Cdd:cd03213  132 LLFLDEPTSGLDSSSALQVMSLLRRL-ADTGRTIICSIHQpSSEIFELFDKLLLLSQG 188
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1-224 1.87e-26

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 105.48  E-value: 1.87e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMS--------LNCQTIDDGD 72
Cdd:PRK09984   1 MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGShiellgrtVQREGRLARD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  73 nwLPPEQRNIGMIFQDYALFPHLTVNQNVGFG-----------LKDLSDQQKKEKVQEmLELVHLDEFGDRYPHQLSGGQ 141
Cdd:PRK09984  81 --IRKSRANTGYIFQQFNLVNRLSVLENVLIGalgstpfwrtcFSWFTREQKQRALQA-LTRVGMVHFAHQRVSTLSGGQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 142 QQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSA 221
Cdd:PRK09984 158 QQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSS 237


                 ...
gi 490872517 222 SEL 224
Cdd:PRK09984 238 QQF 240
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 7-218 4.15e-26

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 108.61  E-value: 4.15e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLplssgimslncqTIDDGDNWLPPEQRnIGMIF 86
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGEL------------EPDSGEVSIPKGLR-IGYLP 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  87 QDYALFPHLTVNQNVGFGLKDLSD-QQKKEKVQEML---------------ELVHLDE---------------FGDRYPH 135
Cdd:COG0488   68 QEPPLDDDLTVLDTVLDGDAELRAlEAELEELEAKLaepdedlerlaelqeEFEALGGweaearaeeilsglgFPEEDLD 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 136 Q----LSGGQQQRVAIARSLAYKPDLLLLDEPfSN---IDTqvrhelISQIRKIFKKQGVTAIFVTHSREeaF--AFADK 206
Cdd:COG0488  148 RpvseLSGGWRRRVALARALLSEPDLLLLDEP-TNhldLES------IEWLEEFLKNYPGTVLVVSHDRY--FldRVATR 218

                        250
                 ....*....|..
gi 490872517 207 MAVMNHGVIEQY 218
Cdd:COG0488  219 ILELDRGKLTLY 230
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 19-224 4.80e-26

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 103.46  E-value: 4.80e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGD-NWLppeQRNIGMIFQDYALFPHlTV 97
Cdd:cd03254   18 VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISrKSL---RSMIGVVLQDTFLFSG-TI 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  98 NQNVGFGlkdlSDQQKKEKVQEMLELVHLDEFGDRYP-----------HQLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:cd03254   94 MENIRLG----RPNATDEEVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILILDEATSN 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 167 IDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03254  170 IDTETEKLIQEALEKLMK--GRTSIIIAH-RLSTIKNADKILVLDDGKIIEEGTHDEL 224
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 5-229 4.85e-26

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 105.96  E-value: 4.85e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQ----TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlSSGIMS----LNCQTIDDgdnwLP 76
Cdd:PRK09473  13 LDVKDLRVTFSTPdgdvTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLA-ANGRIGgsatFNGREILN----LP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 PEQRN------IGMIFQD--YALFPHLTVNQNVGFGL---KDLSDQQKKEKVQEMLELVHLDEFGDR---YPHQLSGGQQ 142
Cdd:PRK09473  88 EKELNklraeqISMIFQDpmTSLNPYMRVGEQLMEVLmlhKGMSKAEAFEESVRMLDAVKMPEARKRmkmYPHEFSGGMR 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 143 QRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSAS 222
Cdd:PRK09473 168 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNAR 247


                 ....*..
gi 490872517 223 ELYFHPS 229
Cdd:PRK09473 248 DVFYQPS 254
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 13-215 7.39e-26

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 103.18  E-value: 7.39e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  13 KYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqtiddgdNWLPPEQRN-----IGMIF- 86
Cdd:cd03267   30 KYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVA--------GLVPWKRRKkflrrIGVVFg 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  87 QDYALFPHLTVNQnvGFGLK----DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:cd03267  102 QKTQLWWDLPVID--SFYLLaaiyDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDE 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490872517 163 PFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:cd03267  180 PTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 13-223 1.02e-25

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 103.24  E-value: 1.02e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  13 KYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQT---IDdgdnwlppeqrnIGMIFQdy 89
Cdd:COG1134   35 RREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRVsalLE------------LGAGFH-- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  90 alfPHLTVNQNVGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDRyP-HQLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:COG1134  101 ---PELTGRENIYLNgrLLGLSRKEIDEKFDEIVEFAELGDFIDQ-PvKTYSSGMRARLAFAVATAVDPDILLVDEVLAV 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 167 IDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:COG1134  177 GDAAFQKKCLARIRE-LRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEE 232
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 5-196 2.37e-25

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 101.10  E-value: 2.37e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQ----- 79
Cdd:PRK13539   3 LEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPD---VAEAchylg 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 -RNigmifqdyALFPHLTVNQNVGF-----GLKDLSdqqkkekVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAY 153
Cdd:PRK13539  80 hRN--------AMKPALTVAENLEFwaaflGGEELD-------IAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVS 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 490872517 154 KPDLLLLDEPFSNIDtqvRH--ELISQIRKIFKKQGVTAIFVTHS 196
Cdd:PRK13539 145 NRPIWILDEPTAALD---AAavALFAELIRAHLAQGGIVIAATHI 186
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 5-220 6.29e-25

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 100.26  E-value: 6.29e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-ImslncqTIDDGD-NWLPPEQ- 79
Cdd:cd03244    3 IEFKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGsI------LIDGVDiSKIGLHDl 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 -RNIGMIFQDYALFPHlTVNQNVgfglkDLSDQQKKEKVQEMLELVHLDEFGDRYPHQL-----------SGGQQQRVAI 147
Cdd:cd03244   77 rSRISIIPQDPVLFSG-TIRSNL-----DPFGEYSDEELWQALERVGLKEFVESLPGGLdtvveeggenlSVGQRQLLCL 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGS 220
Cdd:cd03244  151 ARALLRKSKILVLDEATASVDPETDALIQKTIREAFK--DCTVLTIAH-RLDTIIDSDRILVLDKGRVVEFDS 220
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 5-219 7.79e-25

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 103.77  E-value: 7.79e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG--------IMSLNCQTIDdgdnwlp 76
Cdd:PRK09536   4 IDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGtvlvagddVEALSARAAS------- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 peqRNIGMIFQDYALFPHLTVNQNVGFGLK------DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARS 150
Cdd:PRK09536  77 ---RRVASVPQDTSLSFEFDVRQVVEMGRTphrsrfDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 151 LAYKPDLLLLDEPFSNIDT--QVRH-ELISQIrkifKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:PRK09536 154 LAQATPVLLLDEPTASLDInhQVRTlELVRRL----VDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 5-206 9.74e-25

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 100.17  E-value: 9.74e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ--RNI 82
Cdd:PRK10247   8 LQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIST----LKPEIyrQQV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHlTVNQNVGFGLkdlsdQQKKEKVQEMLELVHLDEFG------DRYPHQLSGGQQQRVAIARSLAYKPD 156
Cdd:PRK10247  84 SYCAQTPTLFGD-TVYDNLIFPW-----QIRNQQPDPAIFLDDLERFAlpdtilTKNIAELSGGEKQRISLIRNLQFMPK 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 490872517 157 LLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEaFAFADK 206
Cdd:PRK10247 158 VLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE-INHADK 206
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 5-198 1.12e-24

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 97.52  E-value: 1.12e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGImslncqtiddgdnwlppeqrnigm 84
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGI------------------------ 56

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 ifqdyalfphLTVNQNVGFGlkdlsdqqkkekvqemlelvhldefgdrYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:cd03221   57 ----------VTWGSTVKIG----------------------------YFEQLSGGEKMRLALAKLLLENPNLLLLDEPT 98

                        170       180       190
                 ....*....|....*....|....*....|....
gi 490872517 165 SNIDTQVRHELISQIRKiFKKqgvTAIFVTHSRE 198
Cdd:cd03221   99 NHLDLESIEALEEALKE-YPG---TVILVSHDRY 128
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 5-217 1.22e-24

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 100.68  E-value: 1.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimSLNCQTIDDGDNWL----PPEQR 80
Cdd:TIGR02323   4 LQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHG--TATYIMRSGAELELyqlsEAERR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NI-----GMIFQDYA--LFPHLTVNQNVGFGLKDLSDQQK---KEKVQEMLELVHLDEFG-DRYPHQLSGGQQQRVAIAR 149
Cdd:TIGR02323  82 RLmrtewGFVHQNPRdgLRMRVSAGANIGERLMAIGARHYgniRATAQDWLEEVEIDPTRiDDLPRAFSGGMQQRLQIAR 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517  150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG-VIEQ 217
Cdd:TIGR02323 162 NLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGrVVES 230
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 5-252 1.84e-24

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 103.73  E-value: 1.84e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTL---LKAVAGLLPLSSGI-----MSLNCQTID------- 69
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLmhvLRGMDQYEPTSGRIiyhvaLCEKCGYVErpskvge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   70 ------------DGDNWLPPE------QRNIGMIFQ-DYALFPHLTVNQNVGFGLKDLSdQQKKEKVQEMLELVHLDEFG 130
Cdd:TIGR03269  81 pcpvcggtlepeEVDFWNLSDklrrriRKRIAIMLQrTFALYGDDTVLDNVLEALEEIG-YEGKEAVGRAVDLIEMVQLS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  131 DRYPH---QLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKM 207
Cdd:TIGR03269 160 HRITHiarDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKA 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 490872517  208 AVMNHGVIEQYGSASELyfhpsskfVADFLGGGSYLNAQRISELE 252
Cdd:TIGR03269 240 IWLENGEIKEEGTPDEV--------VAVFMEGVSEVEKECEVEVG 276
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 5-239 1.92e-24

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 100.24  E-value: 1.92e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGI----------MSLNCQTIDdgdnw 74
Cdd:PRK14243  11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLIPGFrvegkvtfhgKNLYAPDVD----- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  75 lPPE-QRNIGMIFQDYALFPHlTVNQNVGFGLKDLSDQ-QKKEKVQEMLELVHL-DEFGDRYPHQ---LSGGQQQRVAIA 148
Cdd:PRK14243  86 -PVEvRRRIGMVFQKPNPFPK-SIYDNIAYGARINGYKgDMDELVERSLRQAALwDEVKDKLKQSglsLSGGQQQRLCIA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 149 RSLAYKPDLLLLDEPFSNID---TQVRHELISQIrkifkKQGVTAIFVTHSREEAFAFADKMAVMNHGVIE---QYG--- 219
Cdd:PRK14243 164 RAIAVQPEVILMDEPCSALDpisTLRIEELMHEL-----KEQYTIIIVTHNMQQAARVSDMTAFFNVELTEgggRYGylv 238

                        250       260
                 ....*....|....*....|...
gi 490872517 220 --SASELYFH-PSSKFVADFLGG 239
Cdd:PRK14243 239 efDRTEKIFNsPQQQATRDYVSG 261
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 5-217 2.85e-24

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 99.62  E-value: 2.85e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimSLNCQTIDDGDNWL----PPEQR 80
Cdd:PRK11701   7 LSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAG--EVHYRMRDGQLRDLyalsEAERR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NI-----GMIFQDYA--LFPHLTVNQNVGFGLKDLSDQ---QKKEKVQEMLELVHLDEfgDR---YPHQLSGGQQQRVAI 147
Cdd:PRK11701  85 RLlrtewGFVHQHPRdgLRMQVSAGGNIGERLMAVGARhygDIRATAGDWLERVEIDA--ARiddLPTTFSGGMQQRLQI 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG-VIEQ 217
Cdd:PRK11701 163 ARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGrVVES 233
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 5-219 3.47e-24

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 97.38  E-value: 3.47e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLppeQRNI 82
Cdd:cd03247    1 LSINNVSFSYpeQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKAL---SSLI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDyalfPHL---TVNQNVGfglkdlsdqqkkekvqemlelvhldefgdrypHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:cd03247   78 SVLNQR----PYLfdtTLRNNLG--------------------------------RRFSGGERQRLALARILLQDAPIVL 121

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03247  122 LDEPTVGLDPITERQLLSLIFEVLK--DKTLIWITH-HLTGIEHMDKILFLENGKIIMQG 178
cbiO PRK13644
energy-coupling factor transporter ATPase;
20-233 7.31e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 98.91  E-value: 7.31e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLncQTIDDGD-NWLPPEQRNIGMIFQD-YALFPHLTV 97
Cdd:PRK13644  18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLV--SGIDTGDfSKLQGIRKLVGIVFQNpETQFVGRTV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  98 NQNVGFGLKDL--SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHEL 175
Cdd:PRK13644  96 EEDLAFGPENLclPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAV 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 176 ISQIRKIFKKqGVTAIFVTHSREEAFAfADKMAVMNHGVIEQYGSASELYFHPSSKFV 233
Cdd:PRK13644 176 LERIKKLHEK-GKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENVLSDVSLQTL 231
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 15-206 1.06e-23

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 95.68  E-value: 1.06e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  15 ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLncqtiddgdnwlpPEQRNIGMIFQDyALFPH 94
Cdd:cd03223   12 DGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM-------------PEGEDLLFLPQR-PYLPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  95 LTvnqnvgfgLKDLSdqqkkekvqemlelvhldefgdRYP--HQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR 172
Cdd:cd03223   78 GT--------LREQL----------------------IYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESE 127

                        170       180       190
                 ....*....|....*....|....*....|....
gi 490872517 173 HelisQIRKIFKKQGVTAIFVTHsREEAFAFADK 206
Cdd:cd03223  128 D----RLYQLLKELGITVISVGH-RPSLWKFHDR 156
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
5-195 1.71e-23

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 96.03  E-value: 1.71e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlppEQRNigm 84
Cdd:PRK13538   2 LEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQR-----DEYH--- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 ifQDYALFPH-------LTVNQNVGFGLKdLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:PRK13538  74 --QDLLYLGHqpgikteLTALENLRFYQR-LHGPGDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPL 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 490872517 158 LLLDEPFSNIDTQ---VRHELISQirkiFKKQGVTAIFVTH 195
Cdd:PRK13538 151 WILDEPFTAIDKQgvaRLEALLAQ----HAEQGGMVILTTH 187
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-221 1.76e-23

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 96.87  E-value: 1.76e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnWLPPE-- 78
Cdd:PRK11614   2 EKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITD---WQTAKim 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFPHLTVNQNVGFGLKDLSDQQKKEKVQEMLELV-HLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:PRK11614  79 REAVAIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRL 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 158 LLLDEP---FSNIDTQVRHELISQIRkifkKQGVTAIFVTHSREEAFAFADKMAVMNHG--VIEQYGSA 221
Cdd:PRK11614 159 LLLDEPslgLAPIIIQQIFDTIEQLR----EQGMTIFLVEQNANQALKLADRGYVLENGhvVLEDTGDA 223
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
8-222 1.86e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 101.35  E-value: 1.86e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRnIGMIFQ 87
Cdd:NF033858 270 RGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGD--IATRRR-VGYMSQ 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  88 DYALFPHLTVNQNVGFG--LKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:NF033858 347 AFSLYGELTVRQNLELHarLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTS 426

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 166 NIDTQVR----HELISQIRkifkKQGVTaIFV-THSREEAfAFADKMAVMNHG----------VIEQYGSAS 222
Cdd:NF033858 427 GVDPVARdmfwRLLIELSR----EDGVT-IFIsTHFMNEA-ERCDRISLMHAGrvlasdtpaaLVAARGAAT 492
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 5-251 2.09e-23

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 101.09  E-value: 2.09e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY--ESQTI--LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSL--------NCQTIDDGD 72
Cdd:PRK10261  13 LAVENLNIAFmqEQQKIaaVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCdkmllrrrSRQVIELSE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  73 NWLPPEQR----NIGMIFQD--YALFPHLTVNQNVGFGLK---DLSDQQKKEKVQEMLELVHLDE---FGDRYPHQLSGG 140
Cdd:PRK10261  93 QSAAQMRHvrgaDMAMIFQEpmTSLNPVFTVGEQIAESIRlhqGASREEAMVEAKRMLDQVRIPEaqtILSRYPHQLSGG 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 141 QQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGS 220
Cdd:PRK10261 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGS 252

                        250       260       270
                 ....*....|....*....|....*....|.
gi 490872517 221 ASELYFHPSSKFVADFLGGGSYLNAQRISEL 251
Cdd:PRK10261 253 VEQIFHAPQHPYTRALLAAVPQLGAMKGLDY 283
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 1-224 2.10e-23

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 100.51  E-value: 2.10e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIddgdNWLPP--- 77
Cdd:PRK15439   8 APPLLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPC----ARLTPaka 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  78 EQRNIGMIFQDYALFPHLTVNQNVGFGLKdlSDQQKKEKVQEML-EL-VHLDefgdryPHQLSG----GQQQRVAIARSL 151
Cdd:PRK15439  84 HQLGIYLVPQEPLLFPNLSVKENILFGLP--KRQASMQKMKQLLaALgCQLD------LDSSAGslevADRQIVEILRGL 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK15439 156 MRDSRILILDEPTASLTPAETERLFSRIREL-LAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADL 227
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 5-213 2.43e-23

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 96.98  E-value: 2.43e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQ-RNIG 83
Cdd:PRK11300   6 LSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEG----LPGHQiARMG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MI--FQDYALFPHLTVNQNV----------GF--GLKDL-----SDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQR 144
Cdd:PRK11300  82 VVrtFQHVRLFREMTVIENLlvaqhqqlktGLfsGLLKTpafrrAESEALDRAATWLERVGLLEHANRQAGNLAYGQQRR 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 145 VAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK11300 162 LEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQG 230
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 1-213 2.59e-23

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 100.39  E-value: 2.59e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLP--------LSSGiMSLNCQTIDDgd 72
Cdd:PRK13549   2 MEYLLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPhgtyegeiIFEG-EELQASNIRD-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  73 nwlpPEQRNIGMIFQDYALFPHLTVNQN-------VGFGLKDlsDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRV 145
Cdd:PRK13549  79 ----TERAGIAIIHQELALVKELSVLENiflgneiTPGGIMD--YDAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLV 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 146 AIARSLAYKPDLLLLDEPFSNIdTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK13549 153 EIAKALNKQARLLILDEPTASL-TESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDG 219
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 5-218 4.34e-23

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 99.75  E-value: 4.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcQTIddgdnwlppeqrNIGM 84
Cdd:COG0488  316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLG-ETV------------KIGY 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALF-PHLTVNQNvgfgLKDLSDQQKKEKVQEMLELvhldeFG------DRYPHQLSGGQQQRVAIARSLAYKPDL 157
Cdd:COG0488  383 FDQHQEELdPDKTVLDE----LRDGAPGGTEQEVRGYLGR-----FLfsgddaFKPVGVLSGGEKARLALAKLLLSPPNV 453

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKiFKkqGvTAIFVTHSREeaF--AFADKMAVMNHGVIEQY 218
Cdd:COG0488  454 LLLDEPTNHLDIETLEALEEALDD-FP--G-TVLLVSHDRY--FldRVATRILEFEDGGVREY 510
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 5-213 1.28e-22

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 98.36  E-value: 1.28e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLP--------LSSGiMSLNCQTIDDgdnwlp 76
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPhgtwdgeiYWSG-SPLKASNIRD------ 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   77 PEQRNIGMIFQDYALFPHLTVNQNVGFGLK------DLSDQQKKEKVQEMLELVHLDEFGDRYP-HQLSGGQQQRVAIAR 149
Cdd:TIGR02633  75 TERAGIVIIHQELTLVPELSVAENIFLGNEitlpggRMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAK 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517  150 SLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:TIGR02633 155 ALNKQARLLILDEPSSSLTEKETEILLDIIRDL-KAHGVACVYISHKLNEVKAVCDTICVIRDG 217
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 5-228 1.56e-22

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 98.24  E-value: 1.56e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQ----TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS-----SGIMSLNCQTIDDGDnwl 75
Cdd:PRK15134   6 LAIENLSVAFRQQqtvrTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPpvvypSGDIRFHGESLLHAS--- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  76 ppEQR-------NIGMIFQD--YALFPHLTVNQNVGFGLKDLSDQQKKEKVQEMLELvhLDEFGDR--------YPHQLS 138
Cdd:PRK15134  83 --EQTlrgvrgnKIAMIFQEpmVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNC--LDRVGIRqaakrltdYPHQLS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 139 GGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQY 218
Cdd:PRK15134 159 GGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQ 238

                        250
                 ....*....|
gi 490872517 219 GSASELYFHP 228
Cdd:PRK15134 239 NRAATLFSAP 248
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 4-224 1.63e-22

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 98.36  E-value: 1.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLkavaGLL-----PlSSGIMSLNCQTIDDgdnWlp 76
Cdd:PRK11160 338 SLTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLL----QLLtrawdP-QQGEILLNGQPIAD---Y-- 407

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 PEQ---RNIGMIFQDYALFPHlTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEF-------------GDRyphQLSGG 140
Cdd:PRK11160 408 SEAalrQAISVVSQRVHLFSA-TLRDNLLLAAPNASD----EALIEVLQQVGLEKLleddkglnawlgeGGR---QLSGG 479

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 141 QQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFkkQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGS 220
Cdd:PRK11160 480 EQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHA--QNKTVLMITH-RLTGLEQFDRICVMDNGQIIEQGT 556


                 ....
gi 490872517 221 ASEL 224
Cdd:PRK11160 557 HQEL 560
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 5-224 1.80e-22

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 98.25  E-value: 1.80e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQTI--LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqTIDDGDNWLPPEQRNI 82
Cdd:TIGR02203 331 VEFRNVTFRYPGRDRpaLDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLD--GHDLADYTLASLRRQV 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   83 GMIFQDYALFPHlTVNQNVGFGLKDlsdQQKKEKVQEMLELVHLDEFGDRYP---HQ--------LSGGQQQRVAIARSL 151
Cdd:TIGR02203 409 ALVSQDVVLFND-TIANNIAYGRTE---QADRAEIERALAAAYAQDFVDKLPlglDTpigengvlLSGGQRQRLAIARAL 484

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517  152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIFkkQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:TIGR02203 485 LKDAPILILDEATSALDNESERLVQAALERLM--QGRTTLVIAH-RLSTIEKADRIVVMDDGRIVERGTHNEL 554
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 23-228 1.82e-22

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 95.96  E-value: 1.82e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTidDGDNW--LPPEQR------NIGMIFQD--YALF 92
Cdd:PRK11022  26 ISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEF--NGQDLqrISEKERrnlvgaEVAMIFQDpmTSLN 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  93 PHLTVNQNVGFGLKDLSDQQKKEKVQ---EMLELVHLDEFGDR---YPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:PRK11022 104 PCYTVGFQIMEAIKVHQGGNKKTRRQraiDLLNQVGIPDPASRldvYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTA 183

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 167 IDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK11022 184 LDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAP 245
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2-214 1.87e-22

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 96.05  E-value: 1.87e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   2 SCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDGDNWLPPEQR- 80
Cdd:PRK13536  39 TVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAG-------KITVLGVPVPARARl 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 ---NIGMIFQDYALFPHLTVNQN-VGFGLK-DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKP 155
Cdd:PRK13536 112 araRIGVVPQFDNLDLEFTVRENlLVFGRYfGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDP 191

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 156 DLLLLDEPFSNIDTQVRHELISQIRKIFKKqGVTAIFVTHSREEAFAFADKMAVMNHGV 214
Cdd:PRK13536 192 QLLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGR 249
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 5-215 2.64e-22

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 92.59  E-value: 2.64e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGlLP---LSSGIMSLNCQTIDDgdnwLPPEQR- 80
Cdd:cd03217    1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMG-HPkyeVTEGEILFKGEDITD----LPPEERa 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 --NIGMIFQDYALFPHLTVNQ-----NVGFglkdlsdqqkkekvqemlelvhldefgdryphqlSGGQQQRVAIARSLAY 153
Cdd:cd03217   76 rlGIFLAFQYPPEIPGVKNADflryvNEGF----------------------------------SGGEKKRNEILQLLLL 121

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 154 KPDLLLLDEPFSNIDTqVRHELISQIRKIFKKQGVTAIFVTHsREEAFAF--ADKMAVMNHGVI 215
Cdd:cd03217  122 EPDLAILDEPDSGLDI-DALRLVAEVINKLREEGKSVLIITH-YQRLLDYikPDRVHVLYDGRI 183
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 16-225 2.74e-22

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 97.87  E-value: 2.74e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   16 SQTILESLSLEVEHGEIVCLLGASGCGKTTllkaVAGLL-----PlSSGIMSLNCQTIDDGDN-WLppeQRNIGMIFQDY 89
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKST----VAALLqnlyqP-TGGQVLLDGVPLVQYDHhYL---HRQVALVGQEP 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   90 ALFPHlTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSLAYKPDLL 158
Cdd:TIGR00958 565 VLFSG-SVRENIAYGLTDTPD----EEIMAAAKAANAHDFIMEFPNgydtevgekgsQLSGGQKQRIAIARALVRKPRVL 639

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517  159 LLDEPFSNIDTQVRHeLISQIRkifKKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:TIGR00958 640 ILDEATSALDAECEQ-LLQESR---SRASRTVLLIAH-RLSTVERADQILVLKKGSVVEMGTHKQLM 701
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 5-220 2.79e-22

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 92.86  E-value: 2.79e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslnCQTIDDGDNWLPPEQ--- 79
Cdd:cd03369    7 IEVENLSVRYapDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEG-----KIEIDGIDISTIPLEdlr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFPHlTVNQNVgfglkDLSDQQKKEKVQEMLELvhlDEFGDryphQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:cd03369   82 SSLTIIPQDPTLFSG-TIRSNL-----DPFDEYSDEEIYGALRV---SEGGL----NLSQGQRQLLCLARALLKRPRVLV 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFkkQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGS 220
Cdd:cd03369  149 LDEATASIDYATDALIQKTIREEF--TNSTILTIAH-RLRTIIDYDKILVMDAGEVKEYDH 206
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 4-247 3.73e-22

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 94.39  E-value: 3.73e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGI-----MSLNCQTIDDGDNWLPpE 78
Cdd:PRK14271  21 AMAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYrysgdVLLGGRSIFNYRDVLE-F 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFPhLTVNQNVGFGLKDLSDQQKKE---KVQEMLELVHL-DEFGDRY---PHQLSGGQQQRVAIARSL 151
Cdd:PRK14271 100 RRRVGMLFQRPNPFP-MSIMDNVLAGVRAHKLVPRKEfrgVAQARLTEVGLwDAVKDRLsdsPFRLSGGQQQLLCLARTL 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKqgVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSK 231
Cdd:PRK14271 179 AVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHA 256

                        250
                 ....*....|....*...
gi 490872517 232 FVADFLGG--GSYLNAQR 247
Cdd:PRK14271 257 ETARYVAGlsGDVKDAKR 274
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 5-224 7.73e-22

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 96.35  E-value: 7.73e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYE-SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGD--------NWL 75
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDrhtlrqfiNYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   76 PPEQrnigMIFQDyalfphlTVNQNVGFGLKDLSDQqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQR 144
Cdd:TIGR01193 554 PQEP----YIFSG-------SILENLLLGAKENVSQ---DEIWAACEIAEIKDDIENMPLgyqtelseegsSISGGQKQR 619

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  145 VAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKqgvTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:TIGR01193 620 IALARALLTDSKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAH-RLSVAKQSDKIIVLDHGKIIEQGSHDEL 695
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 18-224 1.77e-21

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 95.27  E-value: 1.77e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  18 TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPE--QRNIGMIFQDYALFpHL 95
Cdd:COG5265  372 PILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRD----VTQAslRAAIGIVPQDTVLF-ND 446

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  96 TVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPHQ-----------LSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:COG5265  447 TIAYNIAYGRPDASE----EEVEAAARAAQIHDFIESLPDGydtrvgerglkLSGGEKQRVAIARTLLKNPPILIFDEAT 522

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 165 SNIDTQVRHELISQIRKIfkKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:COG5265  523 SALDSRTERAIQAALREV--ARGRTTLVIAH-RLSTIVDADEILVLEAGRIVERGTHAEL 579
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 23-230 2.12e-21

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 91.68  E-value: 2.12e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlsSGIMSLNCQTIDDGDNWLPPEQR--NIGMIFQD--YALFPHLTVN 98
Cdd:PRK10418  22 VSLTLQRGRVLALVGGSGSGKSLTCAAALGILP--AGVRQTAGRVLLDGKPVAPCALRgrKIATIMQNprSAFNPLHTMH 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  99 QNVGFGLKDLSDQQKKEKVQEMLELVHLDEFG---DRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHEL 175
Cdd:PRK10418 100 THARETCLALGKPADDATLTAALEAVGLENAArvlKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQARI 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 176 ISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHPSS 230
Cdd:PRK10418 180 LDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKH 234
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 7-247 5.88e-21

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 94.31  E-value: 5.88e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517     7 IKDLTCKYE--SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGdnwLPPEQRNIGM 84
Cdd:TIGR01257  931 VKNLVKIFEpsGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETN---LDAVRQSLGM 1007

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    85 IFQDYALFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:TIGR01257 1008 CPQHNILFHHLTVAEHILFyaQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDE 1087

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   163 PFSNIDTQVRHELISQIRKIfkKQGVTAIFVTHSREEAFAFADKMAVMNHGvieqygsasELYFHPSSKFVADFLGGGSY 242
Cdd:TIGR01257 1088 PTSGVDPYSRRSIWDLLLKY--RSGRTIIMSTHHMDEADLLGDRIAIISQG---------RLYCSGTPLFLKNCFGTGFY 1156


                   ....*
gi 490872517   243 LNAQR 247
Cdd:TIGR01257 1157 LTLVR 1161
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 6-276 1.07e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 90.92  E-value: 1.07e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDL-TCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqtiddgdNWLPPEQR---- 80
Cdd:COG4586   23 ALKGLfRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVL--------GYVPFKRRkefa 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 -NIGMIF-QDYALFPHLTVNQNvgFGLK----DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:COG4586   95 rRIGVVFgQRSQLWWDLPAIDS--FRLLkaiyRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHR 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL--YFHPSSKF 232
Cdd:COG4586  173 PKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEELkeRFGPYKTI 252

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 490872517 233 VADFlgggsylnAQRISELEFETSLGVVEAKPQT-EIEFGSACEL 276
Cdd:COG4586  253 VLEL--------AEPVPPLELPRGGEVIEREGNRvRLEVDPRESL 289
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
6-224 1.20e-20

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 89.85  E-value: 1.20e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLppEQRNIGMI 85
Cdd:PRK10575  13 ALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA--FARKVAYL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  86 FQDYALFPHLTVNQNVGFG-------LKDLSdQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:PRK10575  91 PQQLPAAEGMTVRELVAIGrypwhgaLGRFG-AADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCL 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK10575 170 LLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 18-236 1.26e-20

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 92.80  E-value: 1.26e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   18 TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLP---LSSGIMSLNCQTIDdgdnwlPPEQRNI-GMIFQDYALFP 93
Cdd:TIGR00955  39 HLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPkgvKGSGSVLLNGMPID------AKEMRAIsAYVQQDDLFIP 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   94 HLTVNQNVGFGL-----KDLSDQQKKEKVQEMLELVHLDE-----FGDRYPHQ-LSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:TIGR00955 113 TLTVREHLMFQAhlrmpRRVTKKEKRERVDEVLQALGLRKcantrIGVPGRVKgLSGGERKRLAFASELLTDPPLLFCDE 192

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517  163 PFSNIDTQVRHELISQIRKIFKKqGVTAIFVTHS-REEAFAFADKMAVMNHGVIEQYGSASELyfhpsSKFVADF 236
Cdd:TIGR00955 193 PTSGLDSFMAYSVVQVLKGLAQK-GKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPDQA-----VPFFSDL 261
PLN03211 PLN03211
ABC transporter G-25; Provisional
 6-304 1.51e-20

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 92.64  E-value: 1.51e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   6 SIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSgimsLNCQTIDDGDNWLPPEQRNIGMI 85
Cdd:PLN03211  70 KISDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNN----FTGTILANNRKPTKQILKRTGFV 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  86 FQDYALFPHLTVNQNVGFGL-----KDLSDQQK---KEKVQEMLELVHLDE--FGDRYPHQLSGGQQQRVAIARSLAYKP 155
Cdd:PLN03211 146 TQDDILYPHLTVRETLVFCSllrlpKSLTKQEKilvAESVISELGLTKCENtiIGNSFIRGISGGERKRVSIAHEMLINP 225

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 156 DLLLLDEPFSNIDTQVRHELISQIRKIFKKQG--VTAIFVTHSReeAFAFADKMAVMNHG--VIEQYGSASELYFHpSSK 231
Cdd:PLN03211 226 SLLILDEPTSGLDATAAYRLVLTLGSLAQKGKtiVTSMHQPSSR--VYQMFDSVLVLSEGrcLFFGKGSDAMAYFE-SVG 302

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 232 FVADF-LGGGSYLN--AQRISELEfetslGVVE-AKPQTEIEFGSACELLLRPQhIQASYEQDSaISVLEQQFMGDH 304
Cdd:PLN03211 303 FSPSFpMNPADFLLdlANGVCQTD-----GVSErEKPNVKQSLVASYNTLLAPK-VKAAIEMSH-FPQANARFVGSA 372
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 20-223 2.18e-20

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 88.74  E-value: 2.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlSSGIMSLNCQTIDDgdnWLPPEQ-RNIGMIFQDYALFPHLTVN 98
Cdd:COG4138   12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSD---WSAAELaRHRAYLSQQQSPPFAMPVF 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  99 QNVGFGLKDLSDQQKKEKVQEML-ELVHLDEFGDRYPHQLSGGQQQRVAIARSL-----AYKPD--LLLLDEPFSNIDtq 170
Cdd:COG4138   88 QYLALHQPAGASSEAVEQLLAQLaEALGLEDKLSRPLTQLSGGEWQRVRLAAVLlqvwpTINPEgqLLLLDEPMNSLD-- 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 171 VRHE--LISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:COG4138  166 VAQQaaLDRLLRE-LCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAE 219
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
1-215 3.66e-20

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 88.79  E-value: 3.66e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYES-QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGdnwlpPEQ 79
Cdd:PRK15056   3 QQAGIVVNDVTVTWRNgHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQA-----LQK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQ----DYAlFPHLT-----VNQNVGFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARS 150
Cdd:PRK15056  78 NLVAYVPQseevDWS-FPVLVedvvmMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 151 LAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADkMAVMNHGVI 215
Cdd:PRK15056 157 IAQQGQVILLDEPFTGVDVKTEARIISLLREL-RDEGKTMLVSTHNLGSVTEFCD-YTVMVKGTV 219
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-215 4.12e-20

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 90.86  E-value: 4.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYES-QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgdnwLPPEQR-- 80
Cdd:COG3845  257 VLEVENLSVRDDRgVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITG----LSPRERrr 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 -NIGMIFQD---YALFPHLTVNQNVGFGLKDLSDQQK-----KEKVQEM-LELVhlDEFGDRYPH------QLSGGQQQR 144
Cdd:COG3845  333 lGVAYIPEDrlgRGLVPDMSVAENLILGRYRRPPFSRggfldRKAIRAFaEELI--EEFDVRTPGpdtparSLSGGNQQK 410

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 145 VAIARSLAYKPDLLLLDEPFSNID----TQVRHELISQirkifKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:COG3845  411 VILARELSRDPKLLIAAQPTRGLDvgaiEFIHQRLLEL-----RDAGAAVLLISEDLDEILALSDRIAVMYEGRI 480
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 5-195 4.93e-20

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 87.43  E-value: 4.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGL--LPLSSGIMSLNCQTIDDgdnwLPPEQR-- 80
Cdd:COG0396    1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGEDILE----LSPDERar 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 -NIGMIFQDYALFPHLTV--------NQNVGfglKDLSDQQKKEKVQEMLELVHLDE-FGDRYPHQ-LSGGQQQRVAIAR 149
Cdd:COG0396   77 aGIFLAFQYPVEIPGVSVsnflrtalNARRG---EELSAREFLKLLKEKMKELGLDEdFLDRYVNEgFSGGEKKRNEILQ 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490872517 150 SLAYKPDLLLLDEPFSNID---TQVRHELISQIRkifkKQGVTAIFVTH 195
Cdd:COG0396  154 MLLLEPKLAILDETDSGLDidaLRIVAEGVNKLR----SPDRGILIITH 198
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 20-213 9.32e-20

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 86.33  E-value: 9.32e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAG-LLPLSSGIMslncqtIDDGDNWL-----PPEQ------RNIGMIFQ 87
Cdd:COG4778   27 LDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGnYLPDSGSIL------VRHDGGWVdlaqaSPREilalrrRTIGYVSQ 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  88 dyalF----PHLTVNQNVGFGLKDL--SDQQKKEKVQEMLELVHLDE-FGDRYPHQLSGGQQQRVAIARSLAYKPDLLLL 160
Cdd:COG4778  101 ----FlrviPRVSALDVVAEPLLERgvDREEARARARELLARLNLPErLWDLPPATFSGGEQQRVNIARGFIADPPLLLL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490872517 161 DEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:COG4778  177 DEPTASLDAANRAVVVELIEEA-KARGTAIIGIFHDEEVREAVADRVVDVTPF 228
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
5-213 1.04e-19

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 89.84  E-value: 1.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQrNIGM 84
Cdd:PRK09700   6 ISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQL-GIGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQN--VG-------FGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKP 155
Cdd:PRK09700  85 IYQELSVIDELTVLENlyIGrhltkkvCGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 156 DLLLLDEPFSNIdTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK09700 165 KVIIMDEPTSSL-TNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDG 221
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
10-224 1.49e-19

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 86.96  E-value: 1.49e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  10 LTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLplssgimslncqTIDDGDNWLPPEQ---------- 79
Cdd:PRK10253  13 LTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLM------------TPAHGHVWLDGEHiqhyaskeva 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 RNIGMIFQDYALFPHLTVNQNVGFGL---KDLSDQQKKEK---VQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAY 153
Cdd:PRK10253  81 RRIGLLAQNATTPGDITVQELVARGRyphQPLFTRWRKEDeeaVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 154 KPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK10253 161 ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 17-199 6.22e-19

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 84.24  E-value: 6.22e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  17 QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslnCQTIDDGDNWLPPEqrnigmifqdyalfphLT 96
Cdd:COG2401   43 RYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPV-----AGCVDVPDNQFGRE----------------AS 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  97 VNQNVGfglkdlSDQQKKEKVqEMLELVHLdefGD-----RYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQV 171
Cdd:COG2401  102 LIDAIG------RKGDFKDAV-ELLNAVGL---SDavlwlRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQT 171

                        170       180
                 ....*....|....*....|....*...
gi 490872517 172 RHELISQIRKIFKKQGVTAIFVTHsREE 199
Cdd:COG2401  172 AKRVARNLQKLARRAGITLVVATH-HYD 198
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
5-228 9.28e-19

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 85.73  E-value: 9.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT----ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlssgimslncqtiddgDNW------ 74
Cdd:COG4170    4 LDIRNLTIEIDTPQgrvkAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITK----------------DNWhvtadr 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  75 ----------LPPEQR------NIGMIFQDyalfP--HLTVNQNVGFGLKDLSD------------QQKKEKVQEMLELV 124
Cdd:COG4170   68 frwngidllkLSPRERrkiigrEIAMIFQE----PssCLDPSAKIGDQLIEAIPswtfkgkwwqrfKWRKKRAIELLHRV 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 125 ----HLDEFgDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRheliSQIRKIFKK----QGVTAIFVTHS 196
Cdd:COG4170  144 gikdHKDIM-NSYPHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQ----AQIFRLLARlnqlQGTSILLISHD 218

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 490872517 197 REEAFAFADKMAVMNHGVIEQYGSASELY---FHP 228
Cdd:COG4170  219 LESISQWADTITVLYCGQTVESGPTEQILkspHHP 253
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 5-197 3.02e-18

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 81.53  E-value: 3.02e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGdnwLPPEQRNIGM 84
Cdd:PRK13540   2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKD---LCTYQKQLCF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFglkDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:PRK13540  79 VGHRSGINPYLTLRENCLY---DIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPL 155

                        170       180       190
                 ....*....|....*....|....*....|...
gi 490872517 165 SNIDTQVRHELISQIRKiFKKQGVTAIFVTHSR 197
Cdd:PRK13540 156 VALDELSLLTIITKIQE-HRAKGGAVLLTSHQD 187
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-212 3.24e-18

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 82.85  E-value: 3.24e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqtiddgdnwLPPEQR 80
Cdd:PRK09544   1 MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI-------------KRNGKL 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 NIGMIFQDYALFPH--LTVNQnvgfgLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:PRK09544  68 RIGYVPQKLYLDTTlpLTVNR-----FLRLRPGTKKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLL 142

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 159 LLDEPFSNIDT--QVR-HELISQIRKIFkkqGVTAIFVTHSREEAFAFADKMAVMNH 212
Cdd:PRK09544 143 VLDEPTQGVDVngQVAlYDLIDQLRREL---DCAVLMVSHDLHLVMAKTDEVLCLNH 196
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 23-215 3.44e-18

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 85.10  E-value: 3.44e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTI---------DDGDNWLPpEQRNIGMIFQDYAL-- 91
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEInalstaqrlARGLVYLP-EDRQSSGLYLDAPLaw 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  92 -FPHLTVNQNvGFGLKDLSDQQKKEKVQEML--ELVHLDEFGDRyphqLSGGQQQRVAIARSLAYKPDLLLLDEPFSNID 168
Cdd:PRK15439 361 nVCALTHNRR-GFWIKPARENAVLERYRRALniKFNHAEQAART----LSGGNQQKVLIAKCLEASPQLLIVDEPTRGVD 435

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 490872517 169 TQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:PRK15439 436 VSARNDIYQLIRSI-AAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 18-219 7.61e-18

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 80.38  E-value: 7.61e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  18 TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS---SGIMSLNCQTIDDGDNwlpPEQRNIGMIFQDYALFPH 94
Cdd:cd03233   21 PILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAE---KYPGEIIYVSEEDVHFPT 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  95 LTVNQNVGFGLKDLsdqqkkekvqemlelvhldefGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHE 174
Cdd:cd03233   98 LTVRETLDFALRCK---------------------GNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALE 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 490872517 175 LISQIRKIFKKQGVTAIF-VTHSREEAFAFADKMAVMNHGVIEQYG 219
Cdd:cd03233  157 ILKCIRTMADVLKTTTFVsLYQASDEIYDLFDKVLVLYEGRQIYYG 202
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 19-173 8.51e-18

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 80.98  E-value: 8.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDN-WLppeQRNIGMIFQDYALFPHlTV 97
Cdd:cd03248   29 VLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHkYL---HSKVSLVGQEPVLFAR-SL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  98 NQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:cd03248  105 QDNIAYGLQSCSF----ECVKEAAQKAHAHSFISELASgydtevgekgsQLSGGQKQRVAIARALIRNPQVLILDEATSA 180


                 ....*..
gi 490872517 167 IDTQVRH 173
Cdd:cd03248  181 LDAESEQ 187
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 20-215 1.93e-17

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 83.13  E-value: 1.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTID-----DG-DNwlppeqrNIGMIFQDY---A 90
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVtrspqDGlAN-------GIVYISEDRkrdG 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  91 LFPHLTVNQNVGF-GLKDLSDQ----QKKEKVQEMLELVHLdeFGDRYPHQ------LSGGQQQRVAIARSLAYKPDLLL 159
Cdd:PRK10762 341 LVLGMSVKENMSLtALRYFSRAggslKHADEQQAVSDFIRL--FNIKTPSMeqaiglLSGGNQQKVAIARGLMTRPKVLI 418

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 160 LDEPFSNIDTQVRHE---LISQirkiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:PRK10762 419 LDEPTRGVDVGAKKEiyqLINQ----FKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
4-228 2.14e-17

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 82.84  E-value: 2.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDG--DNWlppeQRN 81
Cdd:PRK10789 315 DVNIRQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLqlDSW----RSR 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHlTVNQNVGFGLKDLSDQQKKEKVQemLELVHLD----------EFGDRyPHQLSGGQQQRVAIARSL 151
Cdd:PRK10789 391 LAVVSQTPFLFSD-TVANNIALGRPDATQQEIEHVAR--LASVHDDilrlpqgydtEVGER-GVMLSGGQKQRISIARAL 466

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIfkKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK10789 467 LLNAEILILDDALSAVDGRTEHQILHNLRQW--GEGRTVIISAH-RLSALTEASEILVMQHGHIAQRGNHDQLAQQS 540
GguA NF040905
sugar ABC transporter ATP-binding protein;
20-213 3.36e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 82.14  E-value: 3.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSS--GIMSLN---CQ--TIDDGdnwlppEQRNIGMIFQDYALF 92
Cdd:NF040905  17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDgevCRfkDIRDS------EALGIVIIHQELALI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  93 PHLTVNQNVgFglkdLSDQQKKEKV----------QEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:NF040905  91 PYLSIAENI-F----LGNERAKRGVidwnetnrraRELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDE 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 163 PFSNI---DTQVRHELISQirkiFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:NF040905 166 PTAALneeDSAALLDLLLE----LKAQGITSIIISHKLNEIRRVADSITVLRDG 215
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 23-216 3.58e-17

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 82.15  E-value: 3.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDgDNWlpPEQRN-IGMIFQDYALFPHLtvnqnv 101
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTA-DNR--EAYRQlFSAVFSDFHLFDRL------ 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 102 gFGLKDLSDQqkkEKVQEMLELVHLDE--------FGDRyphQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR- 172
Cdd:COG4615  422 -LGLDGEADP---ARARELLERLELDHkvsvedgrFSTT---DLSQGQRKRLALLVALLEDRPILVFDEWAADQDPEFRr 494

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 490872517 173 ---HELISQirkiFKKQGVTAIFVTHSrEEAFAFADKMAVMNHGVIE 216
Cdd:COG4615  495 vfyTELLPE----LKARGKTVIAISHD-DRYFDLADRVLKMDYGKLV 536
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 20-223 4.87e-17

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 79.21  E-value: 4.87e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlSSGIMSLNCQTIDDGD--------NWLPPEQRN-IGM-IFQDY 89
Cdd:PRK03695  12 LGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAWSaaelarhrAYLSQQQTPpFAMpVFQYL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  90 ALfpHLTVNQNVGFGLKDLSdqqkkekvqEMLELVHLDEFGDRYPHQLSGGQQQRVAIARS-LAYKPD------LLLLDE 162
Cdd:PRK03695  91 TL--HQPDKTRTEAVASALN---------EVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVvLQVWPDinpagqLLLLDE 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517 163 PFSNID-TQVrhELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:PRK03695 160 PMNSLDvAQQ--AALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDE 219
PLN03232 PLN03232
ABC transporter C family member; Provisional
 4-225 1.08e-16

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 81.56  E-value: 1.08e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    4 ALSIKDLTCKYESQT---ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLssgiMSLNCQTIDDGDNWLPpeqr 80
Cdd:PLN03232  614 AISIKNGYFSWDSKTskpTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSH----AETSSVVIRGSVAYVP---- 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFqdyalfpHLTVNQNVGFGLKDLSDQQKKE----KVQEMLELV---HLDEFGDRYPHqLSGGQQQRVAIARSLAY 153
Cdd:PLN03232  686 QVSWIF-------NATVRENILFGSDFESERYWRAidvtALQHDLDLLpgrDLTEIGERGVN-ISGGQKQRVSMARAVYS 757

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490872517  154 KPDLLLLDEPFSNIDTQVRHELISQIRKiFKKQGVTAIFVThSREEAFAFADKMAVMNHGVIEQYGSASELY 225
Cdd:PLN03232  758 NSDIYIFDDPLSALDAHVAHQVFDSCMK-DELKGKTRVLVT-NQLHFLPLMDRIILVSEGMIKEEGTFAELS 827
hmuV PRK13547
heme ABC transporter ATP-binding protein;
5-220 1.19e-16

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 78.72  E-value: 1.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS--------SGIMSLNCQTIDDGD---- 72
Cdd:PRK13547   2 LTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDaprl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  73 ---NWLPPEQRNIGMIFQDYAL-----FPHLTVNQNVGFGLKDLSDQQkkekvqemLELVHLDEFGDRYPHQLSGGQQQR 144
Cdd:PRK13547  82 arlRAVLPQAAQPAFAFSAREIvllgrYPHARRAGALTHRDGEIAWQA--------LALAGATALVGRDVTTLSGGELAR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 145 VAIARSLAY---------KPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:PRK13547 154 VQFARVLAQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAI 233


                 ....*
gi 490872517 216 EQYGS 220
Cdd:PRK13547 234 VAHGA 238
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
20-224 1.42e-16

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 80.39  E-value: 1.42e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLkavaGLL-----PlSSGIMSLNcqTIDDGDNWLPPEQRNIGMIFQDYALFPH 94
Cdd:PRK13657 351 VEDVSFEAKPGQTVAIVGPTGAGKSTLI----NLLqrvfdP-QSGRILID--GTDIRTVTRASLRRNIAVVFQDAGLFNR 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  95 lTVNQNVGFGLKDLSDqqkkEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:PRK13657 424 -SIEDNIRVGRPDATD----EEMRAAAERAQAHDFIERKPDgydtvvgergrQLSGGERQRLAIARALLKDPPILILDEA 498

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 164 FSNID--TQVR-HELISQIRKifkkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK13657 499 TSALDveTEAKvKAALDELMK-----GRTTFIIAH-RLSTVRNADRILVFDNGRVVESGSFDEL 556
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
5-224 1.75e-16

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 80.45  E-value: 1.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTI--LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwLPPEQRNI 82
Cdd:PRK11176 342 IEFRNVTFTYPGKEVpaLRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYT--LASLRNQV 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFpHLTVNQNVGFGLKDlsdQQKKEKVQEMLELVHLDEFGDRYPH-----------QLSGGQQQRVAIARSL 151
Cdd:PRK11176 420 ALVSQNVHLF-NDTIANNIAYARTE---QYSREQIEEAARMAYAMDFINKMDNgldtvigengvLLSGGQRQRIAIARAL 495

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQgvTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PRK11176 496 LRDSPILILDEATSALDTESERAIQAALDELQKNR--TSLVIAH-RLSTIEKADEILVVEDGEIVERGTHAEL 565
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
5-195 2.67e-16

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 76.43  E-value: 2.67e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlppEQRNIGM 84
Cdd:PRK13543  12 LAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGD-----RSRFMAY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFgLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:PRK13543  87 LGHLPGLKADLSTLENLHF-LCGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPY 165

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 490872517 165 SNID----TQVRHELISQIRKifkkqGVTAIFVTH 195
Cdd:PRK13543 166 ANLDlegiTLVNRMISAHLRG-----GGAALVTTH 195
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
1-224 7.66e-16

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 78.22  E-value: 7.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   1 MSCALSIKDLTCKY-ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG--------IMSLNCQTIDDG 71
Cdd:PRK10790 337 QSGRIDIDNVSFAYrDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGeirldgrpLSSLSHSVLRQG 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  72 dnwlppeqrnIGMIFQDYALFPHlTVNQNVGFGlKDLSDqqkkEKVQEMLELVHLDEFGDRYP-----------HQLSGG 140
Cdd:PRK10790 417 ----------VAMVQQDPVVLAD-TFLANVTLG-RDISE----EQVWQALETVQLAELARSLPdglytplgeqgNNLSVG 480

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 141 QQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfkKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGS 220
Cdd:PRK10790 481 QKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAV--REHTTLVVIAH-RLSTIVEADTILVLHRGQAVEQGT 557


                 ....
gi 490872517 221 ASEL 224
Cdd:PRK10790 558 HQQL 561
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 19-255 1.30e-15

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 78.03  E-value: 1.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS------SGIMSLNCQTiddgdNWLPPEqrnigmifqdyalf 92
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSegkikhSGRISFSPQT-----SWIMPG-------------- 501

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    93 phlTVNQNVGFGLKdlSDQQKKEKVqemLELVHLDEFGDRYPHQ-----------LSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:TIGR01271  502 ---TIKDNIIFGLS--YDEYRYTSV---IKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLD 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   162 EPFSNIDTQVRHELI-SQIRKIFKKQgvTAIFVThSREEAFAFADKMAVMNHGVIEQYGSASELYfHPSSKFVADFLGGG 240
Cdd:TIGR01271  574 SPFTHLDVVTEKEIFeSCLCKLMSNK--TRILVT-SKLEHLKKADKILLLHEGVCYFYGTFSELQ-AKRPDFSSLLLGLE 649

                          250
                   ....*....|....*..
gi 490872517   241 SY--LNAQRISELEFET 255
Cdd:TIGR01271  650 AFdnFSAERRNSILTET 666
PLN03130 PLN03130
ABC transporter C family member; Provisional
 4-224 1.73e-15

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 77.86  E-value: 1.73e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    4 ALSIKDLTCKYES---QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlssgIMSLNCQTIDDGDNWLPpeqr 80
Cdd:PLN03130  614 AISIKNGYFSWDSkaeRPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGELP----PRSDASVVIRGTVAYVP---- 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFqdyalfpHLTVNQNVGFGLKdlSDQQKKEKVQEMLELVH---------LDEFGDRYPHqLSGGQQQRVAIARSL 151
Cdd:PLN03130  686 QVSWIF-------NATVRDNILFGSP--FDPERYERAIDVTALQHdldllpggdLTEIGERGVN-ISGGQKQRVSMARAV 755

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517  152 AYKPDLLLLDEPFSNIDTQVRhelisqiRKIFKK------QGVTAIFVThSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:PLN03130  756 YSNSDVYIFDDPLSALDAHVG-------RQVFDKcikdelRGKTRVLVT-NQLHFLSQVDRIILVHEGMIKEEGTYEEL 826
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 5-224 2.68e-15

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 76.55  E-value: 2.68e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTI-LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQRN-I 82
Cdd:PRK10522 323 LELRNVTFAYQDNGFsVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQ---PEDYRKlF 399

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFPHLtvnqnvgfgLKDLSDQQKKEKVQ---EMLELVH-LDEFGDRYPH-QLSGGQQQRVAIARSLAYKPDL 157
Cdd:PRK10522 400 SAVFTDFHLFDQL---------LGPEGKPANPALVEkwlERLKMAHkLELEDGRISNlKLSKGQKKRLALLLALAEERDI 470

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSrEEAFAFADKMAVMNHGVI-EQYGSASEL 224
Cdd:PRK10522 471 LLLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQLsELTGEERDA 537
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 15-195 3.71e-15

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 76.33  E-value: 3.71e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   15 ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTID-DGDNWLPPEQRNIGM-IFQDYALF 92
Cdd:TIGR00954 463 NGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRL-----TKPaKGKLFYVPQRPYMTLgTLRDQIIY 537

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   93 PHlTVNQnvgFGLKDLSDQQkkekVQEMLELVHLDEFGDR---------YPHQLSGGQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:TIGR00954 538 PD-SSED---MKRRGLSDKD----LEQILDNVQLTHILEReggwsavqdWMDVLSGGEKQRIAMARLFYHKPQFAILDEC 609

                         170       180       190
                  ....*....|....*....|....*....|..
gi 490872517  164 FSNIDTQVRHELISQIRKIfkkqGVTAIFVTH 195
Cdd:TIGR00954 610 TSAVSVDVEGYMYRLCREF----GITLFSVSH 637
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
23-223 4.35e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 75.98  E-value: 4.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQRNIGMIF-----QDYALFPHLTV 97
Cdd:PRK09700 282 ISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRS---PLDAVKKGMAYitesrRDNGFFPNFSI 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  98 NQNVG-------------FGLKDLSDQQK-KEKVQEMLELVHLDEfgDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:PRK09700 359 AQNMAisrslkdggykgaMGLFHEVDEQRtAENQRELLALKCHSV--NQNITELSGGNQQKVLISKWLCCCPEVIIFDEP 436

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 164 FSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:PRK09700 437 TRGIDVGAKAEIYKVMRQL-ADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRD 495
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 8-182 5.35e-15

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 76.30  E-value: 5.35e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517     8 KDLT----CKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLP---LSSGIMSLNCQTIDDGdnwlppEQR 80
Cdd:TIGR00956  763 RNLTyevkIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTtgvITGGDRLVNGRPLDSS------FQR 836

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    81 NIGMIFQDYALFPHLTVNQNVGFGL-----KDLSDQQKKEKVQEMLELVHLDEFGDRY---PHQ-LSGGQQQRVAIARSL 151
Cdd:TIGR00956  837 SIGYVQQQDLHLPTSTVRESLRFSAylrqpKSVSKSEKMEYVEEVIKLLEMESYADAVvgvPGEgLNVEQRKRLTIGVEL 916

                          170       180       190
                   ....*....|....*....|....*....|..
gi 490872517   152 AYKPDLLL-LDEPFSNIDTQVRHELISQIRKI 182
Cdd:TIGR00956  917 VAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL 948
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 5-224 5.70e-15

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 74.12  E-value: 5.70e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKY--ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSlncqtidDGDNW----LPPE 78
Cdd:cd03289    3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGDIQI-------DGVSWnsvpLQKW 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  79 QRNIGMIFQDYALFPHlTVNQNVgfglkDLSDQQKKEKVQEMLELVHLDEFGDRYPHQ-----------LSGGQQQRVAI 147
Cdd:cd03289   76 RKAFGVIPQKVFIFSG-TFRKNL-----DPYGKWSDEEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLSHGHKQLMCL 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDTQVrhelISQIRKIFKK--QGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03289  150 ARSVLSKAKILLLDEPSAHLDPIT----YQVIRKTLKQafADCTVILSEH-RIEAMLECQRFLVIEENKVRQYDSIQKL 223
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 20-213 7.52e-15

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 72.75  E-value: 7.52e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcQTIDDGDNWLPPEQRNIGMIfqDYA----LFPHL 95
Cdd:cd03290   17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWS-NKNESEPSFEATRSRNRYSV--AYAaqkpWLLNA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  96 TVNQNVGFGlkDLSDQQKKEKVQEMLEL---VHLDEFGDRYPH-----QLSGGQQQRVAIARSLAYKPDLLLLDEPFSNI 167
Cdd:cd03290   94 TVEENITFG--SPFNKQRYKAVTDACSLqpdIDLLPFGDQTEIgergiNLSGGQRQRICVARALYQNTNIVFLDDPFSAL 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 490872517 168 DTQVRHELISQ-IRKIFKKQGVTAIFVTHsREEAFAFADKMAVMNHG 213
Cdd:cd03290  172 DIHLSDHLMQEgILKFLQDDKRTLVLVTH-KLQYLPHADWIIAMKDG 217
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
20-213 9.55e-15

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 74.95  E-value: 9.55e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQT---------IDDGdnwlppeqrnIGMIFQDYA 90
Cdd:PRK11288  20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEmrfasttaaLAAG----------VAIIYQELH 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  91 LFPHLTVNQNV-------GFGLKDlsdqQKKEKVQEMLELVHLDEfgDRYPHQ----LSGGQQQRVAIARSLAYKPDLLL 159
Cdd:PRK11288  90 LVPEMTVAENLylgqlphKGGIVN----RRLLNYEAREQLEHLGV--DIDPDTplkyLSIGQRQMVEIAKALARNARVIA 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK11288 164 FDEPTSSLSAREIEQLFRVIREL-RAEGRVILYVSHRMEEIFALCDAITVFKDG 216
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 5-232 1.32e-14

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 75.05  E-value: 1.32e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517     5 LSIKDLTCKYE--SQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIddgdnwlppeQRNI 82
Cdd:TIGR01257 1938 LRLNELTKVYSgtSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI----------LTNI 2007

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    83 GMIFQDYALFPHLTVNQNVGFGLKDL--------SDQQKKEKVQEM-LELVHLDEFGDRYPHQLSGGQQQRVAIARSLAY 153
Cdd:TIGR01257 2008 SDVHQNMGYCPQFDAIDDLLTGREHLylyarlrgVPAEEIEKVANWsIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIG 2087

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517   154 KPDLLLLDEPFSNIDTQVRHELISQIRKIFkKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASelyfHPSSKF 232
Cdd:TIGR01257 2088 CPPLVLLDEPTTGMDPQARRMLWNTIVSII-REGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQ----HLKSKF 2161
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 25-208 1.76e-14

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 74.22  E-value: 1.76e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  25 LEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTI-----DDgdnwlPPeqRNI-GMIFqDYalfphltvn 98
Cdd:PRK11147  24 LHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIvarlqQD-----PP--RNVeGTVY-DF--------- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  99 qnVGFGLKDLSDQQKK--------------------EKVQEMLELVHLDEFGDRY----------PHQ----LSGGQQQR 144
Cdd:PRK11147  87 --VAEGIEEQAEYLKRyhdishlvetdpseknlnelAKLQEQLDHHNLWQLENRInevlaqlgldPDAalssLSGGWLRK 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 145 VAIARSLAYKPDLLLLDEPFSNIDTqvrhELISQIRKIFKKQGVTAIFVTHSReeafAFADKMA 208
Cdd:PRK11147 165 AALGRALVSNPDVLLLDEPTNHLDI----ETIEWLEGFLKTFQGSIIFISHDR----SFIRNMA 220
PTZ00243 PTZ00243
ABC transporter; Provisional
 19-232 1.81e-14

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 74.82  E-value: 1.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIddGDNWLPPEQRNIGMIFQDYALFPHlTVN 98
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREI--GAYGLRELRRQFSMIPQDPVLFDG-TVR 1401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   99 QNVgfglkDLSDQQKKEKVQEMLELVHLDEF---------------GDRYphqlSGGQQQRVAIARSLAYK-PDLLLLDE 162
Cdd:PTZ00243 1402 QNV-----DPFLEASSAEVWAALELVGLRERvasesegidsrvlegGSNY----SVGQRQLMCMARALLKKgSGFILMDE 1472

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  163 PFSNIDTQVRHELISQIRKIFkkQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKF 232
Cdd:PTZ00243 1473 ATANIDPALDRQIQATVMSAF--SAYTVITIAH-RLHTVAQYDKIIVMDHGAVAEMGSPRELVMNRQSIF 1539
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
20-195 1.81e-14

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 74.07  E-value: 1.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEI-----VCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcQTIddgdNWLPpeQRnigmIFQDYalfpH 94
Cdd:PRK13409 350 LGDFSLEVEGGEIyegevIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LKI----SYKP--QY----IKPDY----D 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  95 LTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLdefGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHE 174
Cdd:PRK13409 415 GTVEDLLRSITDDLGSSYYKSEIIKPLQLERL---LDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLA 491

                        170       180
                 ....*....|....*....|.
gi 490872517 175 LISQIRKIFKKQGVTAIFVTH 195
Cdd:PRK13409 492 VAKAIRRIAEEREATALVVDH 512
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 19-224 2.55e-14

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 72.20  E-value: 2.55e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIM------SLNCQTiddgdNWLPPEqrnigmifqdyalf 92
Cdd:cd03291   52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIkhsgriSFSSQF-----SWIMPG-------------- 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  93 phlTVNQNVGFGLKdlSDQQKKEKVqemLELVHLDEFGDRYPHQ-----------LSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:cd03291  113 ---TIKENIIFGVS--YDEYRYKSV---VKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLD 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 162 EPFSNIDTQVRHELI-SQIRKIFKKQgvTAIFVThSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:cd03291  185 SPFGYLDVFTEKEIFeSCVCKLMANK--TRILVT-SKMEHLKKADKILILHEGSSYFYGTFSEL 245
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-224 2.65e-14

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 74.01  E-value: 2.65e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMSLncqtidDGD---------- 72
Cdd:NF033858   1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGrVEVL------GGDmadarhrrav 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  73 ----NWLPpeQ---RNigmifqdyaLFPHLTVNQNVGF--GLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQ 143
Cdd:NF033858  75 cpriAYMP--QglgKN---------LYPTLSVFENLDFfgRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQ 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 144 RVAIARSLAYKPDLLLLDEPFSNIDTQVRH---ELISQIRKifKKQGVTAIFVTHSREEAFAFaDKMAVMNHGVIEQYGS 220
Cdd:NF033858 144 KLGLCCALIHDPDLLILDEPTTGVDPLSRRqfwELIDRIRA--ERPGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGT 220


                 ....
gi 490872517 221 ASEL 224
Cdd:NF033858 221 PAEL 224
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 5-222 3.50e-14

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 71.21  E-value: 3.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAG--LLPLSSGIMSLNCQTIDDgdnwLPPEQRN- 81
Cdd:CHL00131   8 LEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGESILD----LEPEERAh 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 --IGMIFQ--------DYALFPHLTVNQNVGF-GLKDLSDQQKKEKVQEMLELVHLDE-FGDRYPHQ-LSGGQQQRVAIA 148
Cdd:CHL00131  84 lgIFLAFQypieipgvSNADFLRLAYNSKRKFqGLPELDPLEFLEIINEKLKLVGMDPsFLSRNVNEgFSGGEKKRNEIL 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 149 RSLAYKPDLLLLDEPFSNIDTQVRHElISQIRKIFKKQGVTAIFVTH-SREEAFAFADKMAVMNHGVIEQYGSAS 222
Cdd:CHL00131 164 QMALLDSELAILDETDSGLDIDALKI-IAEGINKLMTSENSIILITHyQRLLDYIKPDYVHVMQNGKIIKTGDAE 237
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 7-200 4.86e-14

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 72.74  E-value: 4.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS-------------SGimslncQTIDDgdn 73
Cdd:PRK10938 263 LNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGysndltlfgrrrgSG------ETIWD--- 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  74 wlppEQRNIGM----IFQDYalfphlTVNQNV------GF----GL-KDLSDQQKKeKVQEMLELVHLDEFGDRYP-HQL 137
Cdd:PRK10938 334 ----IKKHIGYvsssLHLDY------RVSTSVrnvilsGFfdsiGIyQAVSDRQQK-LAQQWLDILGIDKRTADAPfHSL 402

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 138 SGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRhELISQIRKIFKKQGVTA-IFVTHSREEA 200
Cdd:PRK10938 403 SWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNR-QLVRRFVDVLISEGETQlLFVSHHAEDA 465
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 20-264 5.14e-14

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 73.44  E-value: 5.14e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqtiddGDNWLPPEQrnigmifqdyALFPHLTVNQ 99
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMK------GSVAYVPQQ----------AWIQNDSLRE 717

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   100 NVGFGlKDLSDQQKKEKVQ--------EMLELVHLDEFGDRYPHqLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQV 171
Cdd:TIGR00957  718 NILFG-KALNEKYYQQVLEacallpdlEILPSGDRTEIGEKGVN-LSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHV 795

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   172 -RHELISQIRKIFKKQGVTAIFVTHSReEAFAFADKMAVMNHGVIEQYGSASELYFHPSSkfVADFLggGSYLNAQRISE 250
Cdd:TIGR00957  796 gKHIFEHVIGPEGVLKNKTRILVTHGI-SYLPQVDVIIVMSGGKISEMGSYQELLQRDGA--FAEFL--RTYAPDEQQGH 870

                          250
                   ....*....|....*...
gi 490872517   251 LEFETSLGVV----EAKP 264
Cdd:TIGR00957  871 LEDSWTALVSgegkEAKL 888
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 19-197 1.23e-13

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 71.50  E-value: 1.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGllplssgimslncqtID---DGDNWLPPEqRNIGMIFQDYALFPHL 95
Cdd:TIGR03719  20 ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAG---------------VDkdfNGEARPQPG-IKVGYLPQEPQLDPTK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   96 TVNQNVGFGLKDLSDQQKK----------------------EKVQEMLELVHLDEF---------------GDRYPHQLS 138
Cdd:TIGR03719  84 TVRENVEEGVAEIKDALDRfneisakyaepdadfdklaaeqAELQEIIDAADAWDLdsqleiamdalrcppWDADVTKLS 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517  139 GGQQQRVAIARSLAYKPDLLLLDEPFSNIDTqvrhELISQIRKIFKKQGVTAIFVTHSR 197
Cdd:TIGR03719 164 GGERRRVALCRLLLSKPDMLLLDEPTNHLDA----ESVAWLERHLQEYPGTVVAVTHDR 218
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 5-224 1.26e-13

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 72.25  E-value: 1.26e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517     5 LSIKDLTCKYES--QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPlSSGIMSLncqtidDGDNW----LPPE 78
Cdd:TIGR01271 1218 MDVQGLTAKYTEagRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQI------DGVSWnsvtLQTW 1290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    79 QRNIGMIFQDYALFPHlTVNQNVgfglkDLSDQQKKEKVQEMLELVHLDEFGDRYPHQ-----------LSGGQQQRVAI 147
Cdd:TIGR01271 1291 RKAFGVIPQKVFIFSG-TFRKNL-----DPYEQWSDEEIWKVAEEVGLKSVIEQFPDKldfvlvdggyvLSNGHKQLMCL 1364

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517   148 ARSLAYKPDLLLLDEPFSNIDTqVRHELisqIRKIFKK--QGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:TIGR01271 1365 ARSILSKAKILLLDEPSAHLDP-VTLQI---IRKTLKQsfSNCTVILSEH-RVEALLECQQFLVIEGSSVKQYDSIQKL 1438
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 7-227 1.37e-13

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 71.46  E-value: 1.37e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDL---TCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDgdnwlppeQRNIG 83
Cdd:PRK13545  24 LKDLffrSKDGEYHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKG-------TVDI--------KGSAA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVgfGLKDLSDQQKKEKVQEMLELVhlDEFGD--RYPHQ----LSGGQQQRVAIARSLAYKPDL 157
Cdd:PRK13545  89 LIAISSGLNGQLTGIENI--ELKGLMMGLTKEKIKEIIPEI--IEFADigKFIYQpvktYSSGMKSRLGFAISVHINPDI 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 158 LLLDEPFSNIDTQVRHELISQIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFH 227
Cdd:PRK13545 165 LVIDEALSVGDQTFTKKCLDKMNE-FKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDH 233
PLN03232 PLN03232
ABC transporter C family member; Provisional
 19-254 1.38e-13

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 71.93  E-value: 1.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGDNW---LPPEQRNIGMIFQDYALFphl 95
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRI-----MIDDCDVAkfgLTDLRRVLSIIPQSPVLF--- 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   96 tvNQNVGFGLKDLSDQQKKEkVQEMLELVHLDEFGDRYPHQL-----------SGGQQQRVAIARSLAYKPDLLLLDEPF 164
Cdd:PLN03232 1323 --SGTVRFNIDPFSEHNDAD-LWEALERAHIKDVIDRNPFGLdaevseggenfSVGQRQLLSLARALLRRSKILVLDEAT 1399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  165 SNIDTQVRHELISQIRKIFKKqgVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASELYFHPSSKFVADFLGGGSyLN 244
Cdd:PLN03232 1400 ASVDVRTDSLIQRTIREEFKS--CTMLVIAH-RLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAFFRMVHSTGP-AN 1475

                         250
                  ....*....|
gi 490872517  245 AQRISELEFE 254
Cdd:PLN03232 1476 AQYLSNLVFE 1485
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 80-224 2.00e-13

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 71.60  E-value: 2.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   80 RNIGMIFQDYALFPHLTVNQNVGFGLKDLSdqqkKEKVQEMLELVHLDEFGDRYPHQ-----------LSGGQQQRVAIA 148
Cdd:PTZ00265 1295 RNLFSIVSQEPMLFNMSIYENIKFGKEDAT----REDVKRACKFAAIDEFIESLPNKydtnvgpygksLSGGQKQRIAIA 1370

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  149 RSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHsREEAFAFADKMAVMNH-----GVIEQYGSASE 223
Cdd:PTZ00265 1371 RALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH-RIASIKRSDKIVVFNNpdrtgSFVQAHGTHEE 1449


                  .
gi 490872517  224 L 224
Cdd:PTZ00265 1450 L 1450
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 4-198 2.15e-13

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 70.69  E-value: 2.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   4 ALSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqtiddgdNWlpPEQRNIG 83
Cdd:PRK15064 319 ALEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV-----------KW--SENANIG 385

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYAL-FPH-LTvnqnvgfgLKDLSDQQKKEK-----VQEMLE--LVHLDEFGdRYPHQLSGGQQQRVAIARSLAYK 154
Cdd:PRK15064 386 YYAQDHAYdFENdLT--------LFDWMSQWRQEGddeqaVRGTLGrlLFSQDDIK-KSVKVLSGGEKGRMLFGKLMMQK 456

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 490872517 155 PDLLLLDEPFSNIDTqvrhELISQIRKIFKKQGVTAIFVTHSRE 198
Cdd:PRK15064 457 PNVLVMDEPTNHMDM----ESIESLNMALEKYEGTLIFVSHDRE 496
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
21-215 2.77e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 70.33  E-value: 2.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  21 ESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDnwlPPEQRNIGMIF------QDyALFPH 94
Cdd:PRK11288 270 EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRS---PRDAIRAGIMLcpedrkAE-GIIPV 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  95 LTVNQNVG---------FGLKdLSDQQKKEKVQEMLELVHLDEfgdRYPHQ----LSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:PRK11288 346 HSVADNINisarrhhlrAGCL-INNRWEAENADRFIRSLNIKT---PSREQlimnLSGGNQQKAILGRWLSEDMKVILLD 421

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490872517 162 EPFSNIDTQVRHElISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:PRK11288 422 EPTRGIDVGAKHE-IYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
107-224 3.40e-13

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 69.76  E-value: 3.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 107 DLSDQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFkKQ 186
Cdd:NF000106 115 DLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV-RD 193

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 490872517 187 GVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASEL 224
Cdd:NF000106 194 GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 20-195 5.40e-13

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 69.81  E-value: 5.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHG-----EIVCLLGASGCGKTTLLKAVAGLLplssgimslncqTIDDGdnWLPPE-------QRnigmIFQ 87
Cdd:COG1245  351 YGGFSLEVEGGeiregEVLGIVGPNGIGKTTFAKILAGVL------------KPDEG--EVDEDlkisykpQY----ISP 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  88 DYalfpHLTVNQNVGFGLKD-LSDQQKKEKVQEMLELVHLdefGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSN 166
Cdd:COG1245  413 DY----DGTVEEFLRSANTDdFGSSYYKTEIIKPLGLEKL---LDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAH 485

                        170       180
                 ....*....|....*....|....*....
gi 490872517 167 IDTQVRHELISQIRKIFKKQGVTAIFVTH 195
Cdd:COG1245  486 LDVEQRLAVAKAIRRFAENRGKTAMVVDH 514
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 19-224 1.01e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 69.20  E-value: 1.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncQTIDDGDN----WLPPEQRNIGMIFQDYALFPH 94
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEG------EIIIDGLNiakiGLHDLRFKITIIPQDPVLFSG 1374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    95 lTVNQNVgfglkDLSDQQKKEKVQEMLELVHLDEFGDRYP----HQ-------LSGGQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:TIGR00957 1375 -SLRMNL-----DPFSQYSDEEVWWALELAHLKTFVSALPdkldHEcaeggenLSVGQRQLVCLARALLRKTKILVLDEA 1448

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517   164 FSNIDTQVRHELISQIRKIFkkQGVTAIFVTHSREEAFAFAdKMAVMNHGVIEQYGSASEL 224
Cdd:TIGR00957 1449 TAAVDLETDNLIQSTIRTQF--EDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNL 1506
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 20-222 1.06e-12

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 67.05  E-value: 1.06e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHG-----EIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDdgdnwLPPEQrnigmIFQDYALfph 94
Cdd:cd03237   10 LGEFTLEVEGGsisesEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS-----YKPQY-----IKADYEG--- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  95 lTVNQNVGFGLKDL-SDQQKKEKVQEMLELvhlDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRH 173
Cdd:cd03237   77 -TVRDLLSSITKDFyTHPYFKTEIAKPLQI---EQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRL 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490872517 174 ELISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNhGVIEQYGSAS 222
Cdd:cd03237  153 MASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIVFE-GEPSVNGVAN 200
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 3-182 1.58e-12

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 65.34  E-value: 1.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   3 CALSIKDLT----CKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAG--LLPLSSGIMSLNCQTIDdgdnwlP 76
Cdd:cd03232    2 SVLTWKNLNytvpVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGRPLD------K 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  77 PEQRNIGMIFQDYALFPHLTVNQNVGFG--LKDLSDQQKKekvqemlelvhldefgdryphqlsggqqqRVAIARSLAYK 154
Cdd:cd03232   76 NFQRSTGYVEQQDVHSPNLTVREALRFSalLRGLSVEQRK-----------------------------RLTIGVELAAK 126

                        170       180
                 ....*....|....*....|....*...
gi 490872517 155 PDLLLLDEPFSNIDTQVRHELISQIRKI 182
Cdd:cd03232  127 PSILFLDEPTSGLDSQAAYNIVRFLKKL 154
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
5-228 2.22e-12

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 67.13  E-value: 2.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQ----TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLlplssgimslncqtidDGDNW------ 74
Cdd:PRK15093   4 LDIRNLTIEFKTSdgwvKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV----------------TKDNWrvtadr 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  75 ----------LPPEQR------NIGMIFQD--YALFPHLTVNQNV-----GFGLKDLSDQQKKEKVQEMLELVHLDEFGD 131
Cdd:PRK15093  68 mrfddidllrLSPRERrklvghNVSMIFQEpqSCLDPSERVGRQLmqnipGWTYKGRWWQRFGWRKRRAIELLHRVGIKD 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 132 R------YPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIFVTHSREEAFAFAD 205
Cdd:PRK15093 148 HkdamrsFPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWAD 227

                        250       260
                 ....*....|....*....|...
gi 490872517 206 KMAVMNHGVIEQYGSASELYFHP 228
Cdd:PRK15093 228 KINVLYCGQTVETAPSKELVTTP 250
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
20-236 3.79e-12

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 65.61  E-value: 3.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqtiddGDnwlppeqrnIGMIFQDYALFPHLTVNQ 99
Cdd:PRK13546  40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRN------GE---------VSVIAISAGLSGQLTGIE 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 100 NVGFGLKDLSDQQK--KEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELIS 177
Cdd:PRK13546 105 NIEFKMLCMGFKRKeiKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLD 184

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 178 QIRKiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVIEQYGSASELYFHpSSKFVADF 236
Cdd:PRK13546 185 KIYE-FKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPK-YEAFLNDF 241
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 29-199 3.97e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 63.16  E-value: 3.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    29 HGEIVCLLGASGCGKTTLLKAVAGLL-PLSSGIMSLNCQTIddgdnwlppeqrnigmifqdyalfphltvnqnvgfglkd 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELgPPGGGVIYIDGEDI--------------------------------------- 41

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   108 lsdqqkkekvQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQ- 186
Cdd:smart00382  42 ----------LEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLLLLl 111

                          170
                   ....*....|....*..
gi 490872517   187 ----GVTAIFVTHSREE 199
Cdd:smart00382 112 ksekNLTVILTTNDEKD 128
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 5-213 8.95e-12

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 66.00  E-value: 8.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQT---ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLS-SGIMSLNCQTIDDgDNWLPPEQR 80
Cdd:TIGR02633 258 LEARNLTCWDVINPhrkRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDI-RNPAQAIRA 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   81 NIGMIFQD---YALFPHLTVNQNVGF-------GLKDLSDQQKKEKVQEMLELVHLDEFGDRYP-HQLSGGQQQRVAIAR 149
Cdd:TIGR02633 337 GIAMVPEDrkrHGIVPILGVGKNITLsvlksfcFKMRIDAAAELQIIGSAIQRLKVKTASPFLPiGRLSGGNQQKAVLAK 416

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517  150 SLAYKPDLLLLDEPFSNIDTQVRHElISQIRKIFKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:TIGR02633 417 MLLTNPRVLILDEPTRGVDVGAKYE-IYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEG 479
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 30-182 1.03e-11

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 64.31  E-value: 1.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  30 GEIVCLLGASGCGKTTLLKAVAG-LLPlssgimslNCQTIDDGDNWLPPEQRNIGMIFQDY------------------A 90
Cdd:cd03236   26 GQVLGLVGPNGIGKSTALKILAGkLKP--------NLGKFDDPPDWDEILDEFRGSELQNYftkllegdvkvivkpqyvD 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  91 LFPHlTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLDefgDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQ 170
Cdd:cd03236   98 LIPK-AVKGKVGELLKKKDERGKLDELVDQLELRHVL---DRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIK 173

                        170
                 ....*....|....*....
gi 490872517 171 VR-------HELISQIRKI 182
Cdd:cd03236  174 QRlnaarliRELAEDDNYV 192
PTZ00243 PTZ00243
ABC transporter; Provisional
 15-223 1.28e-11

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 65.96  E-value: 1.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   15 ESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqtiddgdnWlppEQRNIGMIFQDyALFPH 94
Cdd:PTZ00243  671 EPKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV------------W---AERSIAYVPQQ-AWIMN 734

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   95 LTVNQNVGFglkdlSDQQKKEKVQEMLELVHLD------------EFGDRYPHqLSGGQQQRVAIARSLAYKPDLLLLDE 162
Cdd:PTZ00243  735 ATVRGNILF-----FDEEDAARLADAVRVSQLEadlaqlgggletEIGEKGVN-LSGGQKARVSLARAVYANRDVYLLDD 808

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490872517  163 PFSNIDTQVRHELisqIRKIF--KKQGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:PTZ00243  809 PLSALDAHVGERV---VEECFlgALAGKTRVLATH-QVHVVPRADYVVALGDGRVEFSGSSAD 867
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 20-213 1.73e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 65.02  E-value: 1.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMSLNCQTIDDGdnwlpP---EQRNIGMIFQDYALFPHL 95
Cdd:PRK10762  20 LSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGsILYLGKEVTFNG-----PkssQEAGIGIIHQELNLIPQL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  96 TVNQNV--------GFGLKDLsdQQKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNI 167
Cdd:PRK10762  95 TIAENIflgrefvnRFGRIDW--KKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDAL 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 490872517 168 -DTQVRhELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK10762 173 tDTETE-SLFRVIREL-KSQGRGIVYISHRLKEIFEICDDVTVFRDG 217
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 5-215 1.87e-11

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 64.95  E-value: 1.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQT---ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLP-LSSGIMSLNCQTIDDGDnwlpPEQ- 79
Cdd:PRK13549 260 LEVRNLTAWDPVNPhikRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKIRN----PQQa 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  80 --RNIGMIFQD---YALFPHLTVNQNVGfgLKDLSDQQKKEKVQEMLELVHLDEFGDR------YPHQ----LSGGQQQR 144
Cdd:PRK13549 336 iaQGIAMVPEDrkrDGIVPVMGVGKNIT--LAALDRFTGGSRIDDAAELKTILESIQRlkvktaSPELaiarLSGGNQQK 413

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490872517 145 VAIARSLAYKPDLLLLDEPFSNIDTQVRHE---LISQirkiFKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:PRK13549 414 AVLAKCLLLNPKILILDEPTRGIDVGAKYEiykLINQ----LVQQGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 18-237 2.65e-11

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 64.74  E-value: 2.65e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    18 TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVA----GLLPLSSGIMSLNCQTIDDGDNWLPPEQRNIGmifQDYALFP 93
Cdd:TIGR00956   75 DILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDGITPEEIKKHYRGDVVYNA---ETDVHFP 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    94 HLTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLDEF---------------GDRYPHQLSGGQQQRVAIARSLAYKPDLL 158
Cdd:TIGR00956  152 HLTVGETLDFAARCKTPQNRPDGVSREEYAKHIADVymatyglshtrntkvGNDFVRGVSGGERKRVSIAEASLGGAKIQ 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   159 LLDEPFSNIDTQVRHELISQIRKIFKKQGVTAiFVT--HSREEAFAFADKMAVMNHGVIEQYGSASEL--YFH------P 228
Cdd:TIGR00956  232 CWDNATRGLDSATALEFIRALKTSANILDTTP-LVAiyQCSQDAYELFDKVIVLYEGYQIYFGPADKAkqYFEkmgfkcP 310


                   ....*....
gi 490872517   229 SSKFVADFL 237
Cdd:TIGR00956  311 DRQTTADFL 319
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 5-213 2.84e-11

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 64.37  E-value: 2.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKyeSQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQT---------IDDGDNWL 75
Cdd:PRK10982 251 LEVRNLTSL--RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKinnhnaneaINHGFALV 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  76 PPEQRNIGMIFQDYALFPHLTVNQN---VGFGLkdLSDQQKKEKVQEMLELVHLDEFGDRYP-HQLSGGQQQRVAIARSL 151
Cdd:PRK10982 329 TEERRSTGIYAYLDIGFNSLISNIRnykNKVGL--LDNSRMKSDTQWVIDSMRVKTPGHRTQiGSLSGGNQQKVIIGRWL 406

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 152 AYKPDLLLLDEPFSNIDTQVRHE---LISQIRKifKKQGVtaIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK10982 407 LTQPEILMLDEPTRGIDVGAKFEiyqLIAELAK--KDKGI--IIISSEMPELLGITDRILVMSNG 467
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 17-172 8.04e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 60.66  E-value: 8.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  17 QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMSLNCQTiddgDNWLPPEQRNIGmifQDYALFPHL 95
Cdd:PRK13541  13 QKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGnIYYKNCNI----NNIAKPYCTYIG---HNLGLKLEM 85

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517  96 TVNQNVGFGLKDLSdqqKKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVR 172
Cdd:PRK13541  86 TVFENLKFWSEIYN---SAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR 159
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 16-210 1.83e-10

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 61.95  E-value: 1.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  16 SQTILESL-SLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimSLNC-------------QTIDDgDNWlppEQRN 81
Cdd:PRK10938  14 SDTKTLQLpSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSG--ERQSqfshitrlsfeqlQKLVS-DEW---QRNN 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  82 IGMIFQDYALFPHlTVNQNVGFGLKDlsdqqkKEKVQEMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLLLD 161
Cdd:PRK10938  88 TDMLSPGEDDTGR-TTAEIIQDEVKD------PARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490872517 162 EPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVM 210
Cdd:PRK10938 161 EPFDGLDVASRQQLAELLASL-HQSGITLVLVLNRFDEIPDFVQFAGVL 208
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 19-163 2.35e-10

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 61.67  E-value: 2.35e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLlplssgimslncQTIDDGDNWLPPEQRnIGMIFQDYALFPHLTVN 98
Cdd:PRK11819  22 ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV------------DKEFEGEARPAPGIK-VGYLPQEPQLDPEKTVR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  99 QNVGFGLKDLSDQQKK---------EKVQEMLELvhLDEFGD------------------------RYPH------QLSG 139
Cdd:PRK11819  89 ENVEEGVAEVKAALDRfneiyaayaEPDADFDAL--AAEQGElqeiidaadawdldsqleiamdalRCPPwdakvtKLSG 166

                        170       180
                 ....*....|....*....|....
gi 490872517 140 GQQQRVAIARSLAYKPDLLLLDEP 163
Cdd:PRK11819 167 GERRRVALCRLLLEKPDMLLLDEP 190
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 20-213 3.07e-10

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 61.28  E-value: 3.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  20 LESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDDGDNWLPPEQrNIGMIFQDYALFPHLTVNQ 99
Cdd:PRK10982  14 LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEALEN-GISMVHQELNLVLQRSVMD 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 100 NVGFG---LKDL-SDQQKKEKVQEMLelvhLDEFG-DRYPHQ----LSGGQQQRVAIARSLAYKPDLLLLDEPFSNI-DT 169
Cdd:PRK10982  93 NMWLGrypTKGMfVDQDKMYRDTKAI----FDELDiDIDPRAkvatLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLtEK 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 490872517 170 QVRHeLISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHG 213
Cdd:PRK10982 169 EVNH-LFTIIRKL-KERGCGIVYISHKMEEIFQLCDEITILRDG 210
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 19-212 9.07e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 60.04  E-value: 9.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   19 ILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLL-PLSSGIMSLNCQTIDDGD-NWLppeQRNIGMIFQDYALFPHlT 96
Cdd:PTZ00265  400 IYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYdPTEGDIIINDSHNLKDINlKWW---RSKIGVVSQDPLLFSN-S 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   97 VNQNVGFGL-----------------------------------KDLSDQQKKEKVQEMLE------------------- 122
Cdd:PTZ00265  476 IKNNIKYSLyslkdlealsnyynedgndsqenknkrnscrakcaGDLNDMSNTTDSNELIEmrknyqtikdsevvdvskk 555

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  123 -LVH--LDEFGDRY-------PHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQGVTAIF 192
Cdd:PTZ00265  556 vLIHdfVSALPDKYetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITII 635

                         250       260
                  ....*....|....*....|
gi 490872517  193 VTHsREEAFAFADKMAVMNH 212
Cdd:PTZ00265  636 IAH-RLSTIRYANTIFVLSN 654
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 30-168 9.42e-10

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 59.80  E-value: 9.42e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  30 GEIVCLLGASGCGKTTLLKAVAGLLplssgIMSLncqtiddGDNWLPPEQRNI-----GMIFQDYalFPHLtVNQNVGFG 104
Cdd:COG1245   99 GKVTGILGPNGIGKSTALKILSGEL-----KPNL-------GDYDEEPSWDEVlkrfrGTELQDY--FKKL-ANGEIKVA 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 105 LK----DLSDQQKKEKVQEMLELVhlDEFG---------------DRYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFS 165
Cdd:COG1245  164 HKpqyvDLIPKVFKGTVRELLEKV--DERGkldelaeklglenilDRDISELSGGELQRVAIAAALLRDADFYFFDEPSS 241


                 ...
gi 490872517 166 NID 168
Cdd:COG1245  242 YLD 244
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 7-218 1.21e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 59.58  E-value: 1.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   7 IKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimSLNCQTiddgdnwlppeQRNIGMiF 86
Cdd:PRK11147 322 MENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSG--RIHCGT-----------KLEVAY-F 387

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  87 QDY--ALFPHLTVNQNVGFGLKDLSDQQKKEKVqemleLVHLDEF-----GDRYP-HQLSGGQQQRVAIARsLAYKP-DL 157
Cdd:PRK11147 388 DQHraELDPEKTVMDNLAEGKQEVMVNGRPRHV-----LGYLQDFlfhpkRAMTPvKALSGGERNRLLLAR-LFLKPsNL 461

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 158 LLLDEPFSNIDTQVRhELISQIrkIFKKQGvTAIFVTHSReeafAFADKmAVMN------HGVIEQY 218
Cdd:PRK11147 462 LILDEPTNDLDVETL-ELLEEL--LDSYQG-TVLLVSHDR----QFVDN-TVTEcwifegNGKIGRY 519
PLN03130 PLN03130
ABC transporter C family member; Provisional
 2-232 7.54e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 57.44  E-value: 7.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    2 SCALSIKDLTCKYESQ--TILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDGDN---WLP 76
Cdd:PLN03130 1235 SGSIKFEDVVLRYRPElpPVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRI-----LIDGCDIskfGLM 1309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   77 PEQRNIGMIFQDYALFphltvNQNVGFGLkDLSDQQKKEKVQEMLELVHLDEFGDRYPHQL-----------SGGQQQRV 145
Cdd:PLN03130 1310 DLRKVLGIIPQAPVLF-----SGTVRFNL-DPFNEHNDADLWESLERAHLKDVIRRNSLGLdaevseagenfSVGQRQLL 1383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  146 AIARSLAYKPDLLLLDEPFSNIDtqVRHELISQ--IRKIFKkqGVTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASE 223
Cdd:PLN03130 1384 SLARALLRRSKILVLDEATAAVD--VRTDALIQktIREEFK--SCTMLIIAH-RLNTIIDCDRILVLDAGRVVEFDTPEN 1458


                  ....*....
gi 490872517  224 LYFHPSSKF 232
Cdd:PLN03130 1459 LLSNEGSAF 1467
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 5-168 7.90e-09

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 55.57  E-value: 7.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGL--LPLSSGIMSLNCQTIDDgdnwLPPEQR-- 80
Cdd:PRK09580   2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDLLE----LSPEDRag 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  81 -NIGMIFQDYALFPHLTvNQnvgFGLKDLSDQQKKEKVQEMLELVHLDEFGDRYPHQL---------------SGGQQQR 144
Cdd:PRK09580  78 eGIFMAFQYPVEIPGVS-NQ---FFLQTALNAVRSYRGQEPLDRFDFQDLMEEKIALLkmpedlltrsvnvgfSGGEKKR 153

                        170       180
                 ....*....|....*....|....
gi 490872517 145 VAIARSLAYKPDLLLLDEPFSNID 168
Cdd:PRK09580 154 NDILQMAVLEPELCILDESDSGLD 177
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 5-168 1.27e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 56.10  E-value: 1.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517    5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGimslncqTIDDGdnwlppEQRNIGM 84
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSG-------TIEIG------ETVKLAY 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   85 IFQDY-ALFPHLTVNQNVGFGLKDL--------------------SDQQKKEKvqemlelvhldefgdryphQLSGGQQQ 143
Cdd:TIGR03719 390 VDQSRdALDPNKTVWEEISGGLDIIklgkreipsrayvgrfnfkgSDQQKKVG-------------------QLSGGERN 450

                         170       180
                  ....*....|....*....|....*
gi 490872517  144 RVAIARSLAYKPDLLLLDEPFSNID 168
Cdd:TIGR03719 451 RVHLAKTLKSGGNVLLLDEPTNDLD 475
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
30-195 2.15e-08

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 55.59  E-value: 2.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  30 GEIVCLLGASGCGKTTLLKAVAG-LLPlssgimslNCQTIDDGDNWLPPEQRNIGMIFQDYalfphltvnqnvgfgLKDL 108
Cdd:PRK13409  99 GKVTGILGPNGIGKTTAVKILSGeLIP--------NLGDYEEEPSWDEVLKRFRGTELQNY---------------FKKL 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 109 SDQQKK--EKVQ---------------------------EMLELVHLDEFGDRYPHQLSGGQQQRVAIARSLAYKPDLLL 159
Cdd:PRK13409 156 YNGEIKvvHKPQyvdlipkvfkgkvrellkkvdergkldEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYF 235

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 490872517 160 LDEPFSNIDTQVRHELISQIRKIFKKQGVtaIFVTH 195
Cdd:PRK13409 236 FDEPTSYLDIRQRLNVARLIRELAEGKYV--LVVEH 269
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 135-206 3.78e-08

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 51.98  E-value: 3.78e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 135 HQLSGGQQQRVAIARSLA---YKPD-LLLLDEPFSNIDTQVRHELISQIRKIFKKqGVTAIFVTHsREEAFAFADK 206
Cdd:cd03227   76 LQLSGGEKELSALALILAlasLKPRpLYILDEIDRGLDPRDGQALAEAILEHLVK-GAQVIVITH-LPELAELADK 149
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 26-223 5.26e-08

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 52.19  E-value: 5.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  26 EVEHGEIVCLLGASGCGKTTLLKAVAGLLplssgimslncQTIDDGDNWlppeqrnigmifqdyalfPHLTVNQnvgfgl 105
Cdd:cd03222   21 VVKEGEVIGIVGPNGTGKTTAVKILAGQL-----------IPNGDNDEW------------------DGITPVY------ 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 106 kdlsdqqKKEKVQemlelvhldefgdryphqLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKK 185
Cdd:cd03222   66 -------KPQYID------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEE 120

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 490872517 186 QGVTAIFVTHSREEAFAFADKMAVMnHGVIEQYGSASE 223
Cdd:cd03222  121 GKKTALVVEHDLAVLDYLSDRIHVF-EGEPGVYGIASQ 157
PLN03073 PLN03073
ABC transporter F family; Provisional
 24-198 2.62e-07

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 52.17  E-value: 2.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  24 SLEVEHGEIVCLLGASGCGKTTLLKAVAglLPLSSGIMSlNCQTiddgdnwLPPEQRNIG-------------------- 83
Cdd:PLN03073 197 SVTLAFGRHYGLVGRNGTGKTTFLRYMA--MHAIDGIPK-NCQI-------LHVEQEVVGddttalqcvlntdiertqll 266

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 ----MIFQDYALFPHLTVNQNVGFGLKDLSDQ----QKKEKVQEMLELVHLD-----------------EFGDRYPHQLS 138
Cdd:PLN03073 267 eeeaQLVAQQRELEFETETGKGKGANKDGVDKdavsQRLEEIYKRLELIDAYtaearaasilaglsftpEMQVKATKTFS 346

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 139 GGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKkqgvTAIFVTHSRE 198
Cdd:PLN03073 347 GGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPK----TFIVVSHARE 402
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 5-232 4.17e-07

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 50.68  E-value: 4.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYES--QTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqTIDDGDNWLPPEQRNI 82
Cdd:cd03288   20 IKIHDLCVRYENnlKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVID--GIDISKLPLHTLRSRL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  83 GMIFQDYALFphltvNQNVGFGLkdlsDQQKK---EKVQEMLELVHLDEFGDRYPHQL-----------SGGQQQRVAIA 148
Cdd:cd03288   98 SIILQDPILF-----SGSIRFNL----DPECKctdDRLWEALEIAQLKNMVKSLPGGLdavvteggenfSVGQRQLFCLA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517 149 RSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIFKKQgvTAIFVTHsREEAFAFADKMAVMNHGVIEQYGSASELYFHP 228
Cdd:cd03288  169 RAFVRKSSILIMDEATASIDMATENILQKVVMTAFADR--TVVTIAH-RVSTILDADLVLVLSRGILVECDTPENLLAQE 245


                 ....
gi 490872517 229 SSKF 232
Cdd:cd03288  246 DGVF 249
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 5-175 5.92e-07

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 50.94  E-value: 5.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLnCQTIDDGDNwlppEQRNIGM 84
Cdd:PRK10636 313 LKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-AKGIKLGYF----AQHQLEF 387

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTvnqnvgfglkDLSDQQKKEKVQEmlelvHLDEF---GDRYPH---QLSGGQQQRVAIARSLAYKPDLL 158
Cdd:PRK10636 388 LRADESPLQHLA----------RLAPQELEQKLRD-----YLGGFgfqGDKVTEetrRFSGGEKARLVLALIVWQRPNLL 452

                        170
                 ....*....|....*..
gi 490872517 159 LLDEPFSNIDTQVRHEL 175
Cdd:PRK10636 453 LLDEPTNHLDLDMRQAL 469
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 5-198 6.70e-07

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 48.86  E-value: 6.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYesqtiLESLSLEVEHGEIVCLLGASGCGKTTLLKAvagllplssGIMSLNCQTIDDGDNwLPPEQRNIgM 84
Cdd:cd03238    1 LTVSGANVHN-----LQNLDVSIPLNVLVVVTGVSGSGKSTLVNE---------GLYASGKARLISFLP-KFSRNKLI-F 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYAL----FPHLTVNQNVGfglkdlsdqqkkekvqemlelvhldefgdryphQLSGGQQQRVAIARSLA--YKPDLL 158
Cdd:cd03238   65 IDQLQFLidvgLGYLTLGQKLS---------------------------------TLSGGELQRVKLASELFsePPGTLF 111

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 490872517 159 LLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSRE 198
Cdd:cd03238  112 ILDEPSTGLHQQDINQLLEVIKGL-IDLGNTVILIEHNLD 150
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 8-169 7.98e-07

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 50.50  E-value: 7.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   8 KDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSL-----------NCQTIDDGDN-Wl 75
Cdd:PRK11819 328 ENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIgetvklayvdqSRDALDPNKTvW- 406

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  76 ppEQRNIGmifQDYalfphLTVNQN-------VG-FGLKDlSDQQKKEKVqemlelvhldefgdryphqLSGGQQQRVAI 147
Cdd:PRK11819 407 --EEISGG---LDI-----IKVGNReipsrayVGrFNFKG-GDQQKKVGV-------------------LSGGERNRLHL 456

                        170       180
                 ....*....|....*....|..
gi 490872517 148 ARSLAYKPDLLLLDEPFSNIDT 169
Cdd:PRK11819 457 AKTLKQGGNVLLLDEPTNDLDV 478
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 5-198 2.24e-06

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 47.60  E-value: 2.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTIleslslEVEHGeIVCLLGASGCGKTTLLKAVAgllplssgimslncqtiddgdnwlppeqrnigm 84
Cdd:cd03240    4 LSIRNIRSFHERSEI------EFFSP-LTLIVGQNGAGKTTIIEALK--------------------------------- 43

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 ifqdYALFPHLTVNQNVGFGLKDL---------------SDQQKKEKVQ---EMLE---LVHLDEFGD---RYPHQLSGG 140
Cdd:cd03240   44 ----YALTGELPPNSKGGAHDPKLiregevraqvklafeNANGKKYTITrslAILEnviFCHQGESNWpllDMRGRCSGG 119

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490872517 141 QQQ------RVAIARSLAYKPDLLLLDEPFSNIDT-QVRHELISQIRKIFKKQGVTAIFVTHSRE 198
Cdd:cd03240  120 EKVlasliiRLALAETFGSNCGILALDEPTTNLDEeNIEESLAEIIEERKSQKNFQLIVITHDEE 184
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 5-197 1.77e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 46.42  E-value: 1.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTILESLSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNcqtiddgdnwlpPEQRnIGM 84
Cdd:PRK15064   2 LSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLD------------PNER-LGK 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  85 IFQDYALFPHLTVNQNVGFGLKDL-SDQQKKEKVQEMLELVHLD---------EFG--DRYP------------------ 134
Cdd:PRK15064  69 LRQDQFAFEEFTVLDTVIMGHTELwEVKQERDRIYALPEMSEEDgmkvadlevKFAemDGYTaearagelllgvgipeeq 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 135 H-----QLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDtqvrhelISQIR---KIFKKQGVTAIFVTHSR 197
Cdd:PRK15064 149 HyglmsEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLD-------INTIRwleDVLNERNSTMIIISHDR 212
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 131-207 2.31e-05

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 46.36  E-value: 2.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  131 DRYPHQLSGGQQQRVAIARSLAykPDLL----LLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSrEEAFAFADK 206
Cdd:PRK00635  471 ERALATLSGGEQERTALAKHLG--AELIgityILDEPSIGLHPQDTHKLINVIKKL-RDQGNTVLLVEHD-EQMISLADR 546


                  .
gi 490872517  207 M 207
Cdd:PRK00635  547 I 547
PLN03073 PLN03073
ABC transporter F family; Provisional
 33-176 8.24e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 44.47  E-value: 8.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  33 VCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqtiddgdnWLPPEQRnigmifqdYALFPHLTVNqnvgfGLkDLSDQ- 111
Cdd:PLN03073 538 IAMVGPNGIGKSTILKLISGELQPSSGTV------------FRSAKVR--------MAVFSQHHVD-----GL-DLSSNp 591

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490872517 112 -----QKKEKVQEMLELVHLDEFGD------RYPHQLSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELI 176
Cdd:PLN03073 592 llymmRCFPGVPEQKLRAHLGSFGVtgnlalQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALI 667
GguA NF040905
sugar ABC transporter ATP-binding protein;
137-215 1.06e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 44.01  E-value: 1.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517 137 LSGGQQQRVAIARSLAYKPDLLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSREEAFAFADKMAVMNHGVI 215
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINEL-AAEGKGVIVISSELPELLGMCDRIYVMNEGRI 482
SbcC_Walker_B pfam13558
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ...
 136-181 1.34e-04

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.


Pssm-ID: 463921 [Multi-domain]  Cd Length: 90  Bit Score: 40.30  E-value: 1.34e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 490872517  136 QLSGGQQQR---VAIARSLAY----------KPDLLLLDEPFSNIDTQVRHELISQIRK 181
Cdd:pfam13558  32 GLSGGEKQLlayLPLAAALAAqygsaegrppAPRLVFLDEAFAKLDEENIRTALELLRA 90
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 25-72 5.31e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 39.82  E-value: 5.31e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 490872517  25 LEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSG-IMSLNCQTIDDGD 72
Cdd:cd00009   14 LELPPPKNLLLYGPPGTGKTTLARAIANELFRPGApFLYLNASDLLEGL 62
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 137-205 8.93e-04

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 40.32  E-value: 8.93e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490872517 137 LSGGQQQRVAIARSLAYKPD--LLLLDEPFSNIDTQVRHELISQIRKIfKKQGVTAIFVTHSrEEAFAFAD 205
Cdd:cd03270  138 LSGGEAQRIRLATQIGSGLTgvLYVLDEPSIGLHPRDNDRLIETLKRL-RDLGNTVLVVEHD-EDTIRAAD 206
VirB11 COG0630
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ...
 23-84 1.95e-03

Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440395 [Multi-domain]  Cd Length: 462  Bit Score: 39.68  E-value: 1.95e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517  23 LSLEVEHGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMslncqTIDDG-------DNWLP--------PEQRNIGM 84
Cdd:COG0630  283 LWLLLENGKSVLVAGGTASGKTTLLNALLSFIPPDAKIV-----TIEDTrelnlphENWISlvtresfgGEEGDVTM 354
AAA_14 pfam13173
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 29-70 3.27e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 463799 [Multi-domain]  Cd Length: 128  Bit Score: 37.18  E-value: 3.27e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 490872517   29 HGEIVCLLGASGCGKTTLLKAVAGLLPLSSGIMSLNCQTIDD 70
Cdd:pfam13173   1 SRKILVITGPRQVGKTTLLLQLIKELLPPENILYINLDDPRL 42
ABC_SMC3_euk cd03272
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ...
 136-207 5.15e-03

ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213239 [Multi-domain]  Cd Length: 243  Bit Score: 38.01  E-value: 5.15e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490872517 136 QLSGGQQQRVAIARSLA-YKPD---LLLLDEPFSNIDTQVRHELISQIRKIFKK-QGVTAIFvthsREEAFAFADKM 207
Cdd:cd03272  158 QLSGGQKSLVALALIFAiQKCDpapFYLFDEIDAALDAQYRTAVANMIKELSDGaQFITTTF----RPELLEVADKF 230
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
5-182 7.85e-03

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 36.91  E-value: 7.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517   5 LSIKDLTCKYESQTIleslslEVEHGeIVCLLGASGCGKTTLLKAVA-GLLPLSSGIMSLNCQTIDDGDnwlppEQRNIG 83
Cdd:COG0419    5 LRLENFRSYRDTETI------DFDDG-LNLIVGPNGAGKSTILEAIRyALYGKARSRSKLRSDLINVGS-----EEASVE 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490872517  84 MIFQDYALFPHLTVNQNVGFGLKDLSDQQKKEKVQEMLELVHLDEFGDRY------------------------------ 133
Cdd:COG0419   73 LEFEHGGKRYRIERRQGEFAEFLEAKPSERKEALKRLLGLEIYEELKERLkeleealesaleelaelqklkqeilaqlsg 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490872517 134 ---PHQLSGGQQQRVAIARSLAykpdlLLLDepFSNIDTQVRHELISQIRKI 182
Cdd:COG0419  153 ldpIETLSGGERLRLALADLLS-----LILD--FGSLDEERLERLLDALEEL 197
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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