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Conserved domains on  [gi|490982545|ref|WP_004844299|]
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ABC transporter permease [Mediterraneibacter gnavus]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 6-264 1.40e-91

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 271.99  E-value: 1.40e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   6 FRKNEKITVGLILLLLCIFLAVLVPALSPWTSTEMHADIRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALL 85
Cdd:COG1173   12 LRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  86 NGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKERE 165
Cdd:COG1173   92 ALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLRERE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 166 FVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLI 245
Cdd:COG1173  172 YVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPWLALF 251

                        250
                 ....*....|....*....
gi 490982545 246 PTAVLCILILSLNLIGAGL 264
Cdd:COG1173  252 PGLAIVLTVLAFNLLGDGL 270
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 6-264 1.40e-91

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 271.99  E-value: 1.40e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   6 FRKNEKITVGLILLLLCIFLAVLVPALSPWTSTEMHADIRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALL 85
Cdd:COG1173   12 LRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  86 NGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKERE 165
Cdd:COG1173   92 ALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLRERE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 166 FVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLI 245
Cdd:COG1173  172 YVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPWLALF 251

                        250
                 ....*....|....*....
gi 490982545 246 PTAVLCILILSLNLIGAGL 264
Cdd:COG1173  252 PGLAIVLTVLAFNLLGDGL 270
nikC PRK10417
nickel transporter permease NikC; Provisional
 26-264 5.15e-50

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 165.61  E-value: 5.15e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  26 AVLVPALSPWTSTEMHADIRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALLNGALGVLYGAASGYAGKTAD 105
Cdd:PRK10417  20 ALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 106 NILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHL 185
Cdd:PRK10417 100 QATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHL 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490982545 186 LPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLIPTAVLCILILSLNLIGAGL 264
Cdd:PRK10417 180 LPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGLALFISVMAFNLLGDAL 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 73-255 1.07e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.39  E-value: 1.07e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  73 RISLCVGLASALLNGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVG--------LCI 144
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPglglpaliLAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 145 SGWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIpAPRAS 224
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGPG 160

                        170       180       190
                 ....*....|....*....|....*....|.
gi 490982545 225 LGTMIQAARSQifvhPYQMLIPTAVLCILIL 255
Cdd:cd06261  161 TGLLLIFAILF----PGDLGVAAAVALILLL 187
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 99-270 2.65e-14

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 69.25  E-value: 2.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   99 YAGKTADNILMRIADIVASVPS-----LLYVILIMMVLGANEVSILVgLCISGWIETARIVRGEVMRIKEREFVLASRLA 173
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSfvlaiLLVVIAILSILGHGILPAII-LALLGWAGYARLIRRAALRSLPSDLVEAARAL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  174 GAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPaprasLGTMIQAA--RSQIFVHPYQMLIPTAVLC 251
Cdd:pfam00528  90 GASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPG-----LGLLLIEAilGYDYPEIQGPVLAAALILL 164

                         170
                  ....*....|....*....
gi 490982545  252 ILILSLNLIGAGLEAKIRR 270
Cdd:pfam00528 165 LLNLLVDILQRLLDPRVRK 183
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 6-264 1.40e-91

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 271.99  E-value: 1.40e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   6 FRKNEKITVGLILLLLCIFLAVLVPALSPWTSTEMHADIRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALL 85
Cdd:COG1173   12 LRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  86 NGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKERE 165
Cdd:COG1173   92 ALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLRERE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 166 FVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLI 245
Cdd:COG1173  172 YVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPWLALF 251

                        250
                 ....*....|....*....
gi 490982545 246 PTAVLCILILSLNLIGAGL 264
Cdd:COG1173  252 PGLAIVLTVLAFNLLGDGL 270
nikC PRK10417
nickel transporter permease NikC; Provisional
 26-264 5.15e-50

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 165.61  E-value: 5.15e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  26 AVLVPALSPWTSTEMHADIRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALLNGALGVLYGAASGYAGKTAD 105
Cdd:PRK10417  20 ALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 106 NILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHL 185
Cdd:PRK10417 100 QATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHL 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490982545 186 LPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLIPTAVLCILILSLNLIGAGL 264
Cdd:PRK10417 180 LPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGLALFISVMAFNLLGDAL 258
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 27-264 7.63e-50

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 166.16  E-value: 7.63e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  27 VLVPALSPWTSTEMHADIRNQG--ISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALLNGALGVLYGAASGYAGKTA 104
Cdd:PRK15406  54 ILAPMLSQFAYDDTDWGMMSSApdMESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKV 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 105 DNILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTH 184
Cdd:PRK15406 134 DSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRH 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 185 LLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLIPTAVLCILILSLNLIGAGL 264
Cdd:PRK15406 214 IVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGL 293
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 6-264 3.83e-40

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 141.02  E-value: 3.83e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   6 FRKNEKITVGLILLLLCIFLAVLVPALSPWTSTE-MHADIRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASAL 84
Cdd:PRK15082  32 FRRQHVALVAGLFVLLLIVVAIFAPWIAPYDAENyFDYDALNAGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVA 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  85 LNGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKER 164
Cdd:PRK15082 112 IGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQ 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 165 EFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQML 244
Cdd:PRK15082 192 TYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAL 271

                        250       260
                 ....*....|....*....|
gi 490982545 245 IPTAVLCILILSLNLIGAGL 264
Cdd:PRK15082 272 FPSLAIFLTVLAFNLLGDGL 291
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
14-264 3.10e-38

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 136.10  E-value: 3.10e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  14 VGLILLLLCIFLAVLVPALSPWTSTEMHADIRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALLNGALGVLY 93
Cdd:PRK09881  35 TGAVIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  94 GAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVMRIKEREFVLASRLA 173
Cdd:PRK09881 115 GCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTF 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 174 GAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLIPTAVLCIL 253
Cdd:PRK09881 195 GASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLT 274

                        250
                 ....*....|.
gi 490982545 254 ILSLNLIGAGL 264
Cdd:PRK09881 275 AVGFNLFGDGI 285
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
6-264 2.57e-35

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 128.36  E-value: 2.57e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   6 FRKNEKITVGLILLLLCIFLAVLVPALSPWTSTEMHAD------IRNQGISFSHPFGTDKFGRDLFVRVWCGVRISLCVG 79
Cdd:PRK10913  26 FKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDallappVWQEGGSWAHILGTDDVGRDVLSRLMYGARLSLLVG 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  80 LASALLNGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGWIETARIVRGEVM 159
Cdd:PRK10913 106 CLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVL 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 160 RIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGTM----IQAARSQ 235
Cdd:PRK10913 186 VEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMlsdvLQFAQSA 265

                        250       260
                 ....*....|....*....|....*....
gi 490982545 236 IFVhpyqMLIPTAVLCILILSLNLIGAGL 264
Cdd:PRK10913 266 WWV----VTFPGLAILLTVLAFNLMGDGL 290
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 50-264 3.28e-33

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 123.72  E-value: 3.28e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  50 SFSHPFGTDKFGRDLFVRVWCGVRISLCVGLASALLNGALGVLYGAASGYAGKTADNILMRIADIVASVPSLlYVILIMM 129
Cdd:COG4239  118 SAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPEL-YLLIILS 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 130 VLGANEVSILVGLCIS-GWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTE 208
Cdd:COG4239  197 SIFQPSFWLLLGILLLfGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTL 276

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490982545 209 AFLSFMGVGIPAPRASLGTMIQAARSQIFVhPYQMLIPTAVLCILILSLNLIGAGL 264
Cdd:COG4239  277 TSLDFLGFGLPPGSPSLGELLAQGKNNLQA-PWLGLSAFVVLALMLSLLVFIGEAV 331
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
1-273 8.92e-29

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 111.06  E-value: 8.92e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   1 MKQI--NFRKNEKITVGLILLLLCIFLAVLVPALSPWTSTEMHADIR-------NQGiSFSHPFGTDKFGRDLFVRVWCG 71
Cdd:COG4171   16 LKQIwqSFRKNPLAMIGLYGFLFLILLALFGPLLAPYSPDQQFIGALllppswdDNG-DVSFFLGTDDLGRDILSRLLYG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  72 VR----ISLCVGLASALLNGALGVLYGAASGYAGKtadnILMRIADIVASVPSLLYVILIMMVLGANEVSILVGLCISGW 147
Cdd:COG4171   95 ARytfgSALLVVLAAAIIGGIIGILAGMSRGLKSS----ILNHLLDTLLSIPSLLLAIIIVALLGPGLENAMLAITLALL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 148 IETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPAPRASLGT 227
Cdd:COG4171  171 PQFIHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGA 250

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 490982545 228 MIQAARSQIFVHPYQMLIPTAVLCILILSLNLIGAGLEAKIRRRRE 273
Cdd:COG4171  251 MLGDSLELIYLAPWTVILPGLAIMFSVLIVNLVGDGLRRALNKGVE 296
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 55-263 1.24e-25

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 103.52  E-value: 1.24e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  55 FGTDKFGRDLFVRVWCGVRISLCVGLASALLNGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGAN 134
Cdd:PRK15021 123 LGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPN 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 135 EVSILVGLCISGWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFM 214
Cdd:PRK15021 203 FWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFL 282

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490982545 215 GVGIPAPRASLGTMIQAARSQIFVhPYqmLIPTAVLCILILSLNLIGAG 263
Cdd:PRK15021 283 GFGLPLGSPSLGELLLQGKNNLQA-PW--LGITAFLSVAILLSLLIFIG 328
PRK15111 PRK15111
peptide ABC transporter permease SapC;
55-268 6.71e-21

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 89.76  E-value: 6.71e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  55 FGTDKFGRDLFVRVWCG----VRISLCVGLASALLNGALGVLYGAASGYagKTAdnILMRIADIVASVPSLLYVILIMMV 130
Cdd:PRK15111  78 LGTDDLGRDVLSRLLSGaaptVGGAFVVTLAATLCGLVLGVFAGATHGL--RSA--VLNHILDTLLSIPSLLLAIIVVAF 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 131 LGANEVSILVGLCISGWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAF 210
Cdd:PRK15111 154 AGPSLSHAMFAVWLALLPRMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAA 233

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490982545 211 LSFMGVGIPAPRASLGTMIQAARSQIFVHPYQMLIPTAVLCILILSLNLIGAGLEAKI 268
Cdd:PRK15111 234 LGFLDLGAQLPSPEWGAMLGDSLELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAI 291
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 73-255 1.07e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.39  E-value: 1.07e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  73 RISLCVGLASALLNGALGVLYGAASGYAGKTADNILMRIADIVASVPSLLYVILIMMVLGANEVSILVG--------LCI 144
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPglglpaliLAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 145 SGWIETARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIpAPRAS 224
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGPG 160

                        170       180       190
                 ....*....|....*....|....*....|.
gi 490982545 225 LGTMIQAARSQifvhPYQMLIPTAVLCILIL 255
Cdd:cd06261  161 TGLLLIFAILF----PGDLGVAAAVALILLL 187
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 99-270 2.65e-14

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 69.25  E-value: 2.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545   99 YAGKTADNILMRIADIVASVPS-----LLYVILIMMVLGANEVSILVgLCISGWIETARIVRGEVMRIKEREFVLASRLA 173
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSfvlaiLLVVIAILSILGHGILPAII-LALLGWAGYARLIRRAALRSLPSDLVEAARAL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  174 GAGPLRIFLTHLLPNAAGPIVVSLTFLVPQAIFTEAFLSFMGVGIPaprasLGTMIQAA--RSQIFVHPYQMLIPTAVLC 251
Cdd:pfam00528  90 GASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPG-----LGLLLIEAilGYDYPEIQGPVLAAALILL 164

                         170
                  ....*....|....*....
gi 490982545  252 ILILSLNLIGAGLEAKIRR 270
Cdd:pfam00528 165 LLNLLVDILQRLLDPRVRK 183
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 74-217 1.03e-07

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 51.99  E-value: 1.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545  74 ISLCVGLASALLNGALGVLYGAASG-YAGKTADNILMRIADIVASVPSLLYVILIMMVLG---------------ANEVS 137
Cdd:COG0601   97 VTLELALLALLLALLIGIPLGILAAlRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAvklgwlpvsgrvspwEDFLD 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490982545 138 IL---------VGLCISGWIetARIVRGEVMRIKEREFVLASRLAGAGPLRIFLTHLLPNAAGPIV----VSLTFLVPQA 204
Cdd:COG0601  177 ALrhlilpaltLALGSLAGI--ARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVtvlgLQLGGLLGGA 254

                        170
                 ....*....|...
gi 490982545 205 IFTEAFLSFMGVG 217
Cdd:COG0601  255 VVVETVFSWPGLG 267
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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