|
Name |
Accession |
Description |
Interval |
E-value |
| recA |
PRK09354 |
recombinase A; Provisional |
1-347 |
0e+00 |
|
recombinase A; Provisional
Pssm-ID: 236476 [Multi-domain] Cd Length: 349 Bit Score: 694.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 1 MDENKQKALAAALGQIEKQFGKGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIA 80
Cdd:PRK09354 3 MDEEKQKALEAALKQIEKQFGKGSIMRLGDDAAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 81 AAQREGKTCAFIDAEHALDPVYAKKLGVDIDALLVSQPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEIEGEMGD 160
Cdd:PRK09354 83 EAQKAGGTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 161 SHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNE 240
Cdd:PRK09354 163 SHVGLQARLMSQALRKLTGNISKSNTTVIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGNR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 241 TRIKVVKNKIAAPFKEANTQIMYGQGFNREGELVDLGVKHKLVEKAGAWYSYNGDKIGQGKANACNYLREHPEVAKTIDT 320
Cdd:PRK09354 243 TKVKVVKNKVAPPFKQAEFDIMYGEGISREGELIDLGVELGIIEKSGAWYSYNGEKIGQGRENAKQYLKENPELADEIEK 322
|
330 340
....*....|....*....|....*..
gi 491523247 321 KLREMLLAPALAEAPEAGEAPEQAEEF 347
Cdd:PRK09354 323 KIREKLGLSAAAAEEEEEEDEEEEEEE 349
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
1-346 |
0e+00 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 661.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 1 MDENKQKALAAALGQIEKQFGKGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIA 80
Cdd:COG0468 6 ASSEKEKALEAALSQIEKQFGKGSIMRLGDKARQDVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 81 AAQREGKTCAFIDAEHALDPVYAKKLGVDIDALLVSQPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEIEGEMGD 160
Cdd:COG0468 86 EAQKAGGIAAFIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 161 SHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNE 240
Cdd:COG0468 166 SHVGLQARLMSQALRKLTGAISKSNTTVIFINQLREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGNR 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 241 TRIKVVKNKIAAPFKEANTQIMYGQGFNREGELVDLGVKHKLVEKAGAWYSYNGDKIGQGKANACNYLREHPEVAKTIDT 320
Cdd:COG0468 246 TRVKVVKNKVAPPFKEAEFDIMYGEGISKEGELLDLAVELGIIEKSGAWYSYGGERLGQGRENAKQFLKENPELAEEIEA 325
|
330 340
....*....|....*....|....*.
gi 491523247 321 KLREMLLAPALAEAPEAGEAPEQAEE 346
Cdd:COG0468 326 KIREKLGLGAVSEAAAAEEEEDEEEE 351
|
|
| tigrfam_recA |
TIGR02012 |
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ... |
4-324 |
0e+00 |
|
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 162659 [Multi-domain] Cd Length: 321 Bit Score: 600.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 4 NKQKALAAALGQIEKQFGKGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ 83
Cdd:TIGR02012 1 DKQKALEAALAQIEKQFGKGSIMRLGEKTVMDVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEAQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 84 REGKTCAFIDAEHALDPVYAKKLGVDIDALLVSQPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEIEGEMGDSHM 163
Cdd:TIGR02012 81 KAGGTAAFIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 164 GLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNETRI 243
Cdd:TIGR02012 161 GLQARLMSQALRKLTGALSKSNTTAIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTVKQGEEVVGNRTKV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 244 KVVKNKIAAPFKEANTQIMYGQGFNREGELVDLGVKHKLVEKAGAWYSYNGDKIGQGKANACNYLREHPEVAKTIDTKLR 323
Cdd:TIGR02012 241 KVVKNKVAPPFREAEFDILYGEGISKLGEIIDLAVELDIIKKSGSWYSYGDEKLGQGRENAKAFLKENPELAQEIEKKVR 320
|
.
gi 491523247 324 E 324
Cdd:TIGR02012 321 E 321
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
7-268 |
0e+00 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 518.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 7 KALAAALGQIEKQFGKGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREG 86
Cdd:pfam00154 1 KALEAALKQIEKQFGKGSIMKLGDEKKLDVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 87 KTCAFIDAEHALDPVYAKKLGVDIDALLVSQPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEIEGEMGDSHMGLQ 166
Cdd:pfam00154 81 GTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 167 ARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNETRIKVV 246
Cdd:pfam00154 161 ARLMSQALRKLTGSISKSNTTVIFINQIREKIGVMFGNPETTTGGRALKFYASVRLDIRRIGQIKQGEEVIGNKTKVKVV 240
|
250 260
....*....|....*....|..
gi 491523247 247 KNKIAAPFKEANTQIMYGQGFN 268
Cdd:pfam00154 241 KNKVAPPFKEAEFDIMYGEGIS 262
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
35-269 |
1.37e-165 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 460.87 E-value: 1.37e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 35 DVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVYAKKLGVDIDALL 114
Cdd:cd00983 1 DVEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 115 VSQPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQI 194
Cdd:cd00983 81 VSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491523247 195 RMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNETRIKVVKNKIAAPFKEANTQIMYGQGFNR 269
Cdd:cd00983 161 REKIGVMFGNPETTTGGNALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPPFKQAEFDILYGEGISR 235
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
4-252 |
5.61e-118 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 359.02 E-value: 5.61e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 4 NKQKALAAALGQIEKQFGKGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ 83
Cdd:PRK09519 6 DREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 84 REGKTCAFIDAEHALDPVYAKKLGVDIDALLVSQPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEIEGEMGDSHM 163
Cdd:PRK09519 86 AAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 164 GLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNETRI 243
Cdd:PRK09519 166 GLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRV 245
|
....*....
gi 491523247 244 KVVKNKIAA 252
Cdd:PRK09519 246 KVVKNKCLA 254
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
58-226 |
4.18e-59 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 188.72 E-value: 4.18e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 58 GRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVYA-----------KKLGVDIDALLVSQPDTGEQALE 126
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWIDTEGAFPPSRLvqileaspsseLELAEALSRLLYFRPPDTLAHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 127 ICDALARSGA----IDVMVVDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMF 202
Cdd:cd01393 81 ALDSLPESLFpppnTSLVVVDSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRGGS 160
|
170 180
....*....|....*....|....*
gi 491523247 203 G-NPETTTGGNALKFYASVRLDIRR 226
Cdd:cd01393 161 GaSLVPPALGNTWEHSVSTRLLLYR 185
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
245-324 |
4.95e-20 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 91.31 E-value: 4.95e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 245 VVKNKIAAPFKEANTQIMYGQGFNREGELVDLGVKHKLVEKAGAWYSYNGDKIGQGKANACNYLREHPEVAKTIDTKLRE 324
Cdd:PRK09519 687 VVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKE 766
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
39-229 |
1.00e-16 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 77.74 E-value: 1.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEhALDP-----VYAKKLGVDIDAL 113
Cdd:cd01394 1 LSTGSKSLDSLLG-GGVERGTITQIYGPPGSGKTNICLQLAVEAAKQGKKVVYIDTE-GLSPerfqqIAGERFESIASNI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 114 LVSQP-DTGEQALEICDA--LARSGAIDVMVVDSVAALTpKAEiegEMGDSHMglqARMLSQAMRKLTGNLKQSNCMCIF 190
Cdd:cd01394 79 IVFEPySFDEQGVAIQEAekLLKSDKVDLVVVDSATALY-RLE---LGDDSEA---NRELSRQMSKLLSIARKYDIPVVI 151
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 491523247 191 INQIRMKIGVMFGNPettTGGNALKfYAS---VRLDIRRTGA 229
Cdd:cd01394 152 TNQVYSDIDDDRLKP---VGGTLLE-HWSkaiIRLEKSPPGL 189
|
|
| COG4544 |
COG4544 |
Uncharacterized conserved protein [Function unknown]; |
22-152 |
2.57e-15 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 443609 [Multi-domain] Cd Length: 230 Bit Score: 74.20 E-value: 2.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 22 KGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPE-SSGKTTLTLELIAAAQREGKTCAFIDAEHALdp 100
Cdd:COG4544 12 RRRIWRGEGLAAAARAVLPTGFAALDAALPGGGLPRGALHEILGPApGIGELGLLLPLLARLAQAGGPVLWIAPPYDL-- 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 491523247 101 vYA---KKLGVDIDALLVSQPDTGEQALEICDALARSGAIDVMVVDsVAALTPKA 152
Cdd:COG4544 90 -YApglAAAGLDPERLLLVRARRPADALWAAEEALRSGACGAVVAW-LERLDLTA 142
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
39-206 |
3.71e-15 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 73.41 E-value: 3.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPV--YAKKLGVDIDALLVS 116
Cdd:COG0467 2 VPTGIPGLDELLG-GGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEQLlrRAESLGLDLEEYIES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 117 -------------QPDTGEQALEICDALARSGAiDVMVVDSVAALTpkaeiegemgdsHMGLQARMLSQAMRKLTGNLKQ 183
Cdd:COG0467 81 gllriidlspeelGLDLEELLARLREAVEEFGA-KRVVIDSLSGLL------------LALPDPERLREFLHRLLRYLKK 147
|
170 180
....*....|....*....|...
gi 491523247 184 SNCMCIFINQIRMKIGVMFGNPE 206
Cdd:COG0467 148 RGVTTLLTSETGGLEDEATEGGL 170
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
39-226 |
2.04e-13 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 69.25 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ-------REGKtCAFIDAEHALDPV----YAKKLG 107
Cdd:pfam08423 19 ITTGSKELDKLLG-GGIETGSITEIFGEFRTGKTQLCHTLCVTCQlplemggGEGK-ALYIDTEGTFRPErlvaIAERYG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 108 VDIDALLVSQP-------DTGEQALEICDALARSGAIDVMVVDSVAALTpKAEIE--GEMGDSHMglqarMLSQAMRKLT 178
Cdd:pfam08423 97 LDPEDVLDNVAyaraynsEHQMQLLQQAAAMMSESRFALLIVDSATALY-RTDFSgrGELAERQQ-----HLAKFLRTLQ 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 491523247 179 gNLKQSNCMCIFI-NQIRMKIG---VMF-GNPETTTGGNALKFYASVRLDIRR 226
Cdd:pfam08423 171 -RLADEFGVAVVItNQVVAQVDgaaGMFsGDPKKPIGGHIMAHASTTRLSLRK 222
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
39-226 |
8.22e-13 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 67.17 E-value: 8.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ-------REGKtCAFIDAEHALDPV----YAKKLG 107
Cdd:cd01123 1 ITTGSKELDKLLG-GGIETGSITEMFGEFRTGKTQLCHTLAVTCQlpidrggGEGK-AIYIDTEGTFRPErlraIAQRFG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 108 VDIDALL----VSQPDTGEQALEICDALA---RSGAIDVMVVDSVAALTPKAEI-EGEMGDSHMGLqARMLSqAMRKLTg 179
Cdd:cd01123 79 LDPDDVLdnvaYARAFNSDHQTQLLDQAAammVESRFKLLIVDSATALYRTDYSgRGELSARQMHL-AKFLR-MLQRLA- 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 491523247 180 nlKQSNCMCIFINQIRMKIG---VMFGNPETTTGGNALKFYASVRLDIRR 226
Cdd:cd01123 156 --DEFGVAVVVTNQVVAQVDgamMFAADPKKPIGGNILAHASTTRLYLRK 203
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
46-199 |
1.95e-11 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 62.82 E-value: 1.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 46 LDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEhALDPVYAKKLGVD-----IDALLVSQP-D 119
Cdd:TIGR02237 1 IDELLG-GGVERGTITQIYGPPGSGKTNICMILAVNAARQGKKVVYIDTE-GLSPERFKQIAEDrperaLSNFIVFEVfD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 120 TGEQALEICDA--LARSGAIDVMVVDSVAALTpKAEIEGEMGDSHmglqaRMLSQAMRKLTGNLKQSNCMCIFINQIRMK 197
Cdd:TIGR02237 79 FDEQGVAIQKTskFIDRDSASLVVVDSFTALY-RLELSDDRISRN-----RELARQLTLLLSLARKKNLAVVITNQVYTD 152
|
..
gi 491523247 198 IG 199
Cdd:TIGR02237 153 VN 154
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
39-226 |
2.48e-11 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 62.76 E-value: 2.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ-------REGKTCaFIDAEHALDP----VYAKKLG 107
Cdd:cd19514 1 ISTGSTELDKLLG-GGIESMSITEVFGEFRTGKTQLSHTLCVTAQlpgsmggGGGKVA-YIDTEGTFRPdrirPIAERFG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 108 VDIDALL----VSQPDTGEQALEICDALA----RSGAIDVMVVDSVAAL-----TPKaeieGEMGDSHMGLqARMLSqam 174
Cdd:cd19514 79 VDHDAVLdnilYARAYTSEHQMELLDYVAakfhEEAVFRLLIIDSIMALfrvdfSGR----GELAERQQKL-AQMLS--- 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 491523247 175 rKLTGNLKQSNCMCIFINQIRMKIG--VMF-GNPETTTGGNALKFYASVRLDIRR 226
Cdd:cd19514 151 -RLQKISEEYNVAVFITNQVTADPGaaMTFqADPKKPIGGHILAHASTTRISLRK 204
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
39-226 |
6.20e-11 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 61.49 E-value: 6.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLE-LIAAAQREGKTCAFIDA-EHALDPVY-AKKLGVDIDAL-- 113
Cdd:pfam06745 1 VKTGIPGLDEILK-GGFPEGRVVLITGGPGTGKTIFGLQfLYNGALKYGEPGVFVTLeEPPEDLREnARSFGWDLEKLee 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 114 --------LVSQP----------DTGEQALEICDALARSGAiDVMVVDSVAALtpkAEIEGEMgdshmglqarMLSQAMR 175
Cdd:pfam06745 80 egklaiidASTSGigiaevedrfDLEELIERLREAIREIGA-KRVVIDSITTL---FYLLKPA----------VAREILR 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 491523247 176 KLTGNLKQSNCMCIFINQIRMKigvmfgnpETTTGGNALKFYAS---VRLDIRR 226
Cdd:pfam06745 146 RLKRVLKGLGVTAIFTSEKPSG--------EGGIGGYGVEEFIVdgvIRLDLKE 191
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
31-226 |
7.16e-11 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 62.20 E-value: 7.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 31 NRAMDVETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQR-------EGKtCAFIDAEHALDP--- 100
Cdd:PRK04301 76 ERRKNVGKITTGSKELDELLG-GGIETQSITEFYGEFGSGKTQICHQLAVNVQLpeekgglEGK-AVYIDTEGTFRPeri 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 101 -VYAKKLGVDIDALL----VSQP-DTGEQALEICDA--LARSG-AIDVMVVDSVAALTpKAEI--EGEMGDSHMGLqARM 169
Cdd:PRK04301 154 eQMAEALGLDPDEVLdnihVARAyNSDHQMLLAEKAeeLIKEGeNIKLVIVDSLTAHF-RAEYvgRGNLAERQQKL-NKH 231
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 491523247 170 LSQAMRklTGNLkqSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRR 226
Cdd:PRK04301 232 LHDLLR--LADL--YNAAVVVTNQVMARPDAFFGDPTQPIGGHILGHTATFRIYLRK 284
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
58-226 |
2.57e-10 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 58.15 E-value: 2.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 58 GRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVYAKKLGVDIDALLVSqpDTGEQALEICDALARSGAI 137
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKAS--GSGELRLRLALALARKLKP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 138 DVMVVDSVAALTPKAEiegemgdshmgLQARMLSQAMRKLTGNLKQSNCMCIFINqirmkigvmfgNPETTTGGNALKFY 217
Cdd:smart00382 80 DVLILDEITSLLDAEQ-----------EALLLLLEELRLLLLLKSEKNLTVILTT-----------NDEKDLGPALLRRR 137
|
....*....
gi 491523247 218 ASVRLDIRR 226
Cdd:smart00382 138 FDRRIVLLL 146
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
35-226 |
4.98e-10 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 60.18 E-value: 4.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 35 DVETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ---REGKTC---AFIDAEHALDP----VYAK 104
Cdd:PLN03187 104 SVVRITTGSQALDELLG-GGIETRCITEAFGEFRSGKTQLAHTLCVTTQlptEMGGGNgkvAYIDTEGTFRPdrivPIAE 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 105 KLGVDIDALL----VSQPDTGEQALEICDALARSGA---IDVMVVDSVAALTPKAEI-EGEMGDSHMGLqARMLSqamrK 176
Cdd:PLN03187 183 RFGMDADAVLdniiYARAYTYEHQYNLLLGLAAKMAeepFRLLIVDSVIALFRVDFTgRGELAERQQKL-AQMLS----R 257
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 491523247 177 LTGNLKQSNCMCIFINQIRMKIG--VMFGNPETTTGGNALKFYASVRLDIRR 226
Cdd:PLN03187 258 LTKIAEEFNVAVYMTNQVIADPGggMFISDPKKPAGGHVLAHAATIRLMLRK 309
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
39-231 |
5.00e-10 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 58.91 E-value: 5.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQR-------EGKtCAFIDAEHALDP----VYAKKLG 107
Cdd:cd19515 1 ISTGSKELDKLLG-GGIETQAITEVFGEFGSGKTQLCHQLAVNVQLppeegglNGK-AVYIDTENTFRPerimQMAKALG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 108 VDIDALL----VSQP-DTGEQAL---EICDALARSGAIDVMVVDSVAALTpKAEI--EGEMGDSHMGLqARMLSQAMRkl 177
Cdd:cd19515 79 LDPDEVLdniyVARAyNSNHQMLlveKAEDLIKEGNNIKLLIVDSLTSHF-RAEYvgRGTLAERQQKL-NKHLHDLHR-- 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 491523247 178 TGNLkqSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIK 231
Cdd:cd19515 155 LADL--YNIAVLVTNQVMAKPDAFFGDPTQAIGGHILGHAATFRVYLRKGKGGK 206
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
1-226 |
5.26e-10 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 59.79 E-value: 5.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 1 MDENKQKALAAALGQIEkQFGKGSIMRLGDNRAMdVETISTGSLSLDIALGAGGLPMGrIVEIYGPESSGKTTLTLELIA 80
Cdd:TIGR02238 42 LSEAKVDKIKEAASKII-NPGFITAFEISQKRKK-VLKITTGSQALDGILGGGIESMS-ITEVFGEFRCGKTQLSHTLCV 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 81 AAQ-------REGKTCaFIDAEHALDP----VYAKKLGVDIDA----LLVSQPDTGEQALEICDALARSGAID---VMVV 142
Cdd:TIGR02238 119 TAQlpremggGNGKVA-YIDTEGTFRPdrirAIAERFGVDPDAvldnILYARAYTSEHQMELLDYLAAKFSEEpfrLLIV 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 143 DSVAAL-TPKAEIEGEMGDshmglQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIG--VMF-GNPETTTGGNALKFYA 218
Cdd:TIGR02238 198 DSIMALfRVDFSGRGELSE-----RQQKLAQMLSRLNKISEEFNVAVFVTNQVQADPGatMTFiADPKKPIGGHVLAHAS 272
|
....*...
gi 491523247 219 SVRLDIRR 226
Cdd:TIGR02238 273 TTRILLRK 280
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
37-199 |
6.97e-10 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 58.33 E-value: 6.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 37 ETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEhALDPVYAKKL-GVDIDALL- 114
Cdd:PRK09361 3 ERLPTGCKMLDELLG-GGFERGTITQIYGPPGSGKTNICLQLAVEAAKNGKKVIYIDTE-GLSPERFKQIaGEDFEELLs 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 115 ---VSQP-DTGEQALEICDALARSGA-IDVMVVDSVAALTpKAEIEGEMGDSHMglqARMLSQAMRKLTGNLKQSNCMCI 189
Cdd:PRK09361 81 niiIFEPsSFEEQSEAIRKAEKLAKEnVGLIVLDSATSLY-RLELEDEEDNSKL---NRELGRQLTHLLKLARKHDLAVV 156
|
170
....*....|
gi 491523247 190 FINQIRMKIG 199
Cdd:PRK09361 157 ITNQVYSDID 166
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
39-195 |
4.78e-09 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 55.73 E-value: 4.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVY--AKKLGVDIDA---- 112
Cdd:cd01124 1 VKTGIPGLDELLG-GGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGEPGLFFTFEESPERLLrnAKSFGWDFDEmede 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 113 --LLVSQPDTGEQALEICDALA-------RSGAIDVMVVDSVAALTPKAEiegemgdshmglQARMLSQAMRKLTGNLKQ 183
Cdd:cd01124 80 gkLIIVDAPPTEAGRFSLDELLsrilsiiKSFKAKRVVIDSLSGLRRAKE------------DQMRARRIVIALLNELRA 147
|
170
....*....|..
gi 491523247 184 SNCMCIFINQIR 195
Cdd:cd01124 148 AGVTTIFTSEMR 159
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
39-226 |
1.27e-08 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 54.63 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQR-------EGKtCAFIDAEHALDPV----YAKKLG 107
Cdd:cd19513 1 ITTGSKELDKLLG-GGIETGSITELFGEFRTGKTQLCHTLAVTCQLpidqgggEGK-ALYIDTEGTFRPErllaIAERYG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 108 VDIDALL--VS-----QPDTGEQALEICDALARSGAIDVMVVDSVAALTpKAEIEGEmGDshmgLQARM--LSQAMRKLT 178
Cdd:cd19513 79 LNGEDVLdnVAyarayNTDHQMQLLIQASAMMAESRYALLIVDSATALY-RTDYSGR-GE----LSARQmhLAKFLRMLQ 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 491523247 179 GNLKQSNCMCIFINQIRMKI--GVMF-GNPETTTGGNALKFYASVRLDIRR 226
Cdd:cd19513 153 RLADEFGVAVVITNQVVAQVdgAAMFaGDPKKPIGGNIMAHASTTRLYLRK 203
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
47-226 |
1.43e-08 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 54.63 E-value: 1.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 47 DIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAA----QREGKT--CAFIDAEHALDP-------------VYAKKLG 107
Cdd:cd19493 1 DTALA-GGLPLGAITEITGASGSGKTQFALTLASSAampaRKGGLDggVLYIDTESKFSAerlaeiaearfpeAFSGFME 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 108 VDIDA------LLVSQPDTGEQALEICDAL---ARSGAIDVMVVDSVAALTPKaeiegEMGDSHMGLQARMlsQAMRKLT 178
Cdd:cd19493 80 ENERAeemlkrVAVVRVTTLAQLLERLPNLeehILSSGVRLVVIDSIAALVRR-----EFGGSDGEVTERH--NALAREA 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 491523247 179 GNLK---QSNCMCIF-INQIRMKIGVMFGNPETTTG--GNALKFYASVRLDIRR 226
Cdd:cd19493 153 SSLKrlaEEFRIAVLvTNQATTHFGDAGDGSSGVTAalGDAWAHAVNTRLRLER 206
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
39-226 |
6.33e-08 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 53.46 E-value: 6.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQR-------EGKtCAFIDAEHALDP----VYAKKLG 107
Cdd:PTZ00035 100 ITTGSTQLDKLLG-GGIETGSITELFGEFRTGKTQLCHTLCVTCQLpieqgggEGK-VLYIDTEGTFRPerivQIAERFG 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 108 VDIDALL----VSQPDTGEQALEICDALARSGAID---VMVVDSVAALTpkaEIE----GEMGDSHMGLqARMLSqAMRK 176
Cdd:PTZ00035 178 LDPEDVLdniaYARAYNHEHQMQLLSQAAAKMAEErfaLLIVDSATALF---RVDysgrGELAERQQHL-GKFLR-ALQK 252
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 491523247 177 LTgnlKQSNCMCIFINQIRMKIG---VMFGNPETTTGGNALKFYASVRLDIRR 226
Cdd:PTZ00035 253 LA---DEFNVAVVITNQVMADVDgasMFVADPKKPIGGHIIAHASTTRLSLRK 302
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
46-194 |
2.08e-07 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 51.52 E-value: 2.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 46 LDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQR------EGKTCAFIDAEHAL----------------DPVYA 103
Cdd:cd19491 1 LDELLG-GGIPVGGITEIAGESGAGKTQLCLQLALTVQLprelggLGGGAVYICTESSFpskrlqqlasslpkryHLEKA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 104 KKLGVDIdaLLVSQPDTgeQALEIC-----DALARSGAIDVMVVDSVAALtpkaeIEGEMGDSHMGLQARmlSQAMRKLT 178
Cdd:cd19491 80 KNFLDNI--FVEHVADL--ETLEHClnyqlPALLERGPIRLVVIDSIAAL-----FRSEFDTSRSDLVER--AKYLRRLA 148
|
170 180
....*....|....*....|
gi 491523247 179 GNLKQ----SNCMCIFINQI 194
Cdd:cd19491 149 DHLKRladkYNLAVVVVNQV 168
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
35-226 |
8.59e-07 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 50.12 E-value: 8.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 35 DVETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ-------REGKtCAFIDAEHALDP----VYA 103
Cdd:PLN03186 101 EIIQITTGSRELDKILE-GGIETGSITEIYGEFRTGKTQLCHTLCVTCQlpldqggGEGK-AMYIDTEGTFRPqrliQIA 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 104 KKLGVDIDALL----VSQPDTGEQALEICDALARSGAID---VMVVDSVAALTpKAEIEGEmGDshmgLQAR--MLSQAM 174
Cdd:PLN03186 179 ERFGLNGADVLenvaYARAYNTDHQSELLLEAASMMAETrfaLMIVDSATALY-RTEFSGR-GE----LSARqmHLGKFL 252
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 491523247 175 RKLTGNLKQSNCMCIFINQIRMKI--GVMFGNPETT-TGGNALKFYASVRLDIRR 226
Cdd:PLN03186 253 RSLQRLADEFGVAVVITNQVVAQVdgSAFFAGPQLKpIGGNIMAHASTTRLALRK 307
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
35-226 |
4.01e-06 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 47.80 E-value: 4.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 35 DVETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQ-------REGKtCAFIDAEHALDPV----YA 103
Cdd:TIGR02239 74 EVIQLTTGSKELDKLLG-GGIETGSITEIFGEFRTGKTQLCHTLAVTCQlpidqggGEGK-ALYIDTEGTFRPErllaIA 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 104 KKLGVDIDALL--VS-----QPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEI-EGEMGDSHMGLqARMLsqamR 175
Cdd:TIGR02239 152 ERYGLNPEDVLdnVAyarayNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSgRGELSARQMHL-ARFL----R 226
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 491523247 176 KLTGNLKQSNCMCIFINQIRMKI---GVMF-GNPETTTGGNALKFYASVRLDIRR 226
Cdd:TIGR02239 227 SLQRLADEFGVAVVITNQVVAQVdgaGSMFaGDPKKPIGGNIMAHASTTRLSLRK 281
|
|
| KaiC-like_N |
cd19488 |
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
39-150 |
7.01e-06 |
|
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410896 [Multi-domain] Cd Length: 225 Bit Score: 46.57 E-value: 7.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFI---DAEHALDPVyAKKLGVDIDALLV 115
Cdd:cd19488 1 ISTGIPGLDDILR-GGLPPRRLYLVEGAPGTGKTTLALQFLLEGAANGETGLYItlsETEQELRAV-ALSHGWSLDGIHI 78
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 491523247 116 ---SQPDTGEQALEICDAL----ARSGAIDVMVVDSVAALTP 150
Cdd:cd19488 79 felSPSESALDAAQQYTILhpseLELSETTRLIFERVERLKP 120
|
|
| FlaH |
COG2874 |
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility]; |
37-96 |
9.08e-06 |
|
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
Pssm-ID: 442121 Cd Length: 230 Bit Score: 46.36 E-value: 9.08e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 37 ETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEH 96
Cdd:COG2874 1 EIISTGNDELDKRLG-GGIPLGSLVLIEGENGTGKSVLSQQFAYGALENGLSVTYISTEL 59
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
26-145 |
1.20e-05 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 45.99 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 26 MRLGDNRAMDVETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPV--YA 103
Cdd:cd01121 51 LPLSDVEAEEEERISTGIGELDRVLG-GGLVPGSVVLIGGDPGIGKSTLLLQVAARLAQRGGKVLYVSGEESLSQIklRA 129
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 491523247 104 KKLGVDIDALLVsqpdTGEQALEICDALARSGAIDVMVVDSV 145
Cdd:cd01121 130 ERLGLGSDNLYL----LAETNLEAILAEIEELKPSLVVIDSI 167
|
|
| KaiC_C |
cd19484 |
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ... |
39-149 |
5.32e-05 |
|
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410892 [Multi-domain] Cd Length: 218 Bit Score: 43.86 E-value: 5.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 39 ISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVY--AKKLGVDIDALLVS 116
Cdd:cd19484 1 ISTGIPRLDAMLGGGGFFRGSSILVSGATGTGKTLLAASFADAACRRGERCLYFAFEESPAQLIrnAKSIGIDLEQMERK 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 491523247 117 Q---------PDTG-EQALEICDALARSGAIDVMVVDSVAALT 149
Cdd:cd19484 81 GllkiicarpELYGlEDHLIIIKSEINEFKPSRVIVDPLSALA 123
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
55-254 |
1.37e-04 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 43.35 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 55 LPMGRIVEIYGPESSGKTTLTLELIAAA---------QREGKTCAFIDAEHALDPV------YAKKLGVD---------- 109
Cdd:COG3598 10 LPEGGVTLLAGPPGTGKSFLALQLAAAVaaggpwlgrRVPPGKVLYLAAEDDRGELrrrlkaLGADLGLPfadldgrlrl 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 110 IDALLVSQPDTGEQALEicdALARSGAIDVMVVDSVAALTPkaeiegemGDSHMGLQARMLSQAMRKLtgnLKQSNCMCI 189
Cdd:COG3598 90 LSLAGDLDDTDDLEALE---RAIEEEGPDLVVIDPLARVFG--------GDENDAEEMRAFLNPLDRL---AERTGAAVL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491523247 190 FINQIRmKIGVMFGNPETTTGGNALKFYASVRLDIRRTgaiKEGDEVVgnetrIKVVKNKIAAPF 254
Cdd:COG3598 156 LVHHTG-KGGAGKDSGDRARGSSALRGAARSVLVLSRE---KGEDLRV-----LTRAKSNYGPEI 211
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
58-199 |
1.50e-04 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 42.34 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 58 GRIVEIYGPESSGKTTLTLELIAAA---------QREGKTCA--FIDAEHALDP-----VYAKKLGVDIDALLVSQPDTG 121
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAARCilpsswggvPLGGLEAAvvFIDTDGRFDIlrlrsILEARIRAAIQAANSSDDEED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 122 -EQALEIC--------------------------DALARSGAIDVMVVDSVAAL-----TPKAEIEGEMGDSHMGLQArm 169
Cdd:cd19490 81 vEEIAREClqrlhifrchsslqllatllslenylLSLSANPELGLLLIDSISAFywqdrFSAELARAAPLLQEAALRA-- 158
|
170 180 190
....*....|....*....|....*....|
gi 491523247 170 LSQAMRKLTgnlKQSNCMCIFINQIRMKIG 199
Cdd:cd19490 159 ILRELRRLR---RRFQLVVIATKQALFPGK 185
|
|
| PRK06067 |
PRK06067 |
flagellar accessory protein FlaH; Validated |
35-95 |
1.87e-04 |
|
flagellar accessory protein FlaH; Validated
Pssm-ID: 180381 Cd Length: 234 Bit Score: 42.27 E-value: 1.87e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491523247 35 DVETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAE 95
Cdd:PRK06067 3 KKEIISTGNEELDRKLG-GGIPFPSLILIEGDHGTGKSVLSQQFVYGALKQGKKVYVITTE 62
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
59-152 |
2.21e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 40.40 E-value: 2.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 59 RIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEH-----ALDPVYAKKLGVDIDALLVSQPDTGeqalEICDALAR 133
Cdd:pfam13401 6 GILVLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSgtspkDLLRALLRALGLPLSGRLSKEELLA----ALQQLLLA 81
|
90
....*....|....*....
gi 491523247 134 SGAIDVMVVDSVAALTPKA 152
Cdd:pfam13401 82 LAVAVVLIIDEAQHLSLEA 100
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
53-93 |
2.73e-04 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 41.47 E-value: 2.73e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 491523247 53 GGLPMGRIVEIYGPESSGKTTLTLELIA-AAQREGKTCAFID 93
Cdd:cd19489 2 GGLRTGEITELVGESSSGKTQLCLTAAAnVASRSGQNVLYID 43
|
|
| AAA_24 |
pfam13479 |
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins. |
57-145 |
4.90e-04 |
|
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
Pssm-ID: 433243 Cd Length: 199 Bit Score: 40.77 E-value: 4.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 57 MGRIVEIYGPESSGKTTLTLELiaaaqreGKTcAFIDAEHALDPVYAKKLGVDIDallvsqPDTGEQALEICDALARSG- 135
Cdd:pfam13479 1 KKLKILIYGPSGIGKTTFAKTL-------PKP-LFLDTEKGSKALDGDRFPDIVI------RDSWQDFLDAIDELTAAEl 66
|
90
....*....|.
gi 491523247 136 -AIDVMVVDSV 145
Cdd:pfam13479 67 aDYKTIVIDTV 77
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
26-199 |
1.36e-03 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 40.25 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 26 MRLgDNRAMDvETISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVY--A 103
Cdd:PRK09302 244 MRL-TQRSSN-ERISSGVPDLDEMLG-GGFFRGSIILVSGATGTGKTLLASKFAEAACRRGERCLLFAFEESRAQLIrnA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491523247 104 KKLGVDIDA-----LLVSQPDTGEQA-LE-----ICDALARSGAiDVMVVDSVAALTPkaeiegemGDSHMGLQARMLsq 172
Cdd:PRK09302 321 RSWGIDLEKmeekgLLKIICARPESYgLEdhliiIKREIEEFKP-SRVAIDPLSALAR--------GGSLNEFRQFVI-- 389
|
170 180
....*....|....*....|....*..
gi 491523247 173 amrKLTGNLKQSNCMCIFINQIRMKIG 199
Cdd:PRK09302 390 ---RLTDYLKSEEITGLFTNLTPDFMG 413
|
|
| KaiC-like_C |
cd19487 |
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
39-114 |
5.05e-03 |
|
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410895 [Multi-domain] Cd Length: 219 Bit Score: 37.66 E-value: 5.05e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491523247 39 ISTGSLSLDIALGaGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVY--AKKLGVDIDALL 114
Cdd:cd19487 1 VSSGVPELDELLG-GGLERGTSTLLIGPAGVGKSTLALQFAKAAAARGERSVLFSFDESIGTLFerSEALGIDLRAMV 77
|
|
| PAXNEB |
pfam05625 |
PAXNEB protein; PAXNEB or PAX6 neighbour is found in several eukaryotic organizms. PAXNED is ... |
38-73 |
7.91e-03 |
|
PAXNEB protein; PAXNEB or PAX6 neighbour is found in several eukaryotic organizms. PAXNED is an RNA polymerase II Elongator protein subunit. It is part of the HAP subcomplex of Elongator, which is a six-subunit component of the RNA polymerase II holoenzyme. The HAP subcomplex is required for Elongator structural integrity and histone acetyltransferase activity. This protein family has a P-loop-like motif and adopts a RecA-ATPase-like fold, lacking the conserved sequence signature of ATPases.
Pssm-ID: 461696 Cd Length: 359 Bit Score: 37.96 E-value: 7.91e-03
10 20 30
....*....|....*....|....*....|....*.
gi 491523247 38 TISTGSLSLDIALGaGGLPMGRIVEIygpESSGKTT 73
Cdd:pfam05625 18 TTSTGTPSLDKLLG-GGLPLGSSLLI---EEDGTTD 49
|
|
| NadR3 |
COG3172 |
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase ... |
59-78 |
8.01e-03 |
|
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase is part of the Pathway/BioSystem: NAD biosynthesis
Pssm-ID: 442405 [Multi-domain] Cd Length: 178 Bit Score: 36.72 E-value: 8.01e-03
|
| |
