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Conserved domains on  [gi|491648627|ref|WP_005506153|]
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L-lactate permease [Grimontia hollisae]

Protein Classification

L-lactate permease( domain architecture ID 10004073)

L-lactate permease plays a role in L-lactate utilization by transporting L-lactate across the membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
1-555 0e+00

L-lactate permease [Energy production and conversion];


:

Pssm-ID: 441227  Cd Length: 520  Bit Score: 538.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   1 MNDTLLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITVSVLWIVFGAIFLLN 80
Cdd:COG1620    1 MSLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGLPILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  81 TLKHTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA 160
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 161 VGTPIIVGVN-KGLDTHNIGQalvengstweiylqqitsSVAIIHAIVGILMPVLMAMMLTRFfgknKSWTEgldILPFA 239
Cdd:COG1620  161 VGTPIIVGAQvTGLDALEIGA------------------MVGRQLPILSLLIPFLLVWILDGW----RGIKE---VWPAA 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 240 IFAGLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSPENEWPAEwlgslkmDLNENAGKPMNL 319
Cdd:COG1620  216 LVAGLSFAVPQFLTANFLGPELPDIIAGLVGLAALVLFLR--FWKPKEIWDFAPEEEWPAE-------EEDAEKLSAMSL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 320 ALAWAPYVLLAVVLVASRVSAEFKSLLLSVNVTFS----NILGETGISAAIQPLYLPGGILVFVALIAVIIQAGSAKPLG 395
Cdd:COG1620  287 LKAWSPYLLLIVLLVLTRLPPPVKALLNSTTLKIPwpglLGAGTTGASYSFNPLYAPGTAILLAALITILLLRMSPGQAK 366
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 396 KALGESTKTLIGAGFVLVFTIPMVRIFINSGingadlasMPVTTANFASGLVGDAFPMLSAAIGALGAFIAGSNTVSNMM 475
Cdd:COG1620  367 RAFKETLKQLRGPILTLAFVLALAYVMNYSG--------MPATLGLALAAATGAAFPFFAPFLGWLGVFITGSDTSSNAL 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 476 FSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLPTIYYLLAAGVIGMVAIYGL 555
Cdd:COG1620  439 FGGLQFTTAEQLGLSPTLIVAAQSVGGVMGKMISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
1-555 0e+00

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 538.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   1 MNDTLLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITVSVLWIVFGAIFLLN 80
Cdd:COG1620    1 MSLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGLPILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  81 TLKHTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA 160
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 161 VGTPIIVGVN-KGLDTHNIGQalvengstweiylqqitsSVAIIHAIVGILMPVLMAMMLTRFfgknKSWTEgldILPFA 239
Cdd:COG1620  161 VGTPIIVGAQvTGLDALEIGA------------------MVGRQLPILSLLIPFLLVWILDGW----RGIKE---VWPAA 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 240 IFAGLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSPENEWPAEwlgslkmDLNENAGKPMNL 319
Cdd:COG1620  216 LVAGLSFAVPQFLTANFLGPELPDIIAGLVGLAALVLFLR--FWKPKEIWDFAPEEEWPAE-------EEDAEKLSAMSL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 320 ALAWAPYVLLAVVLVASRVSAEFKSLLLSVNVTFS----NILGETGISAAIQPLYLPGGILVFVALIAVIIQAGSAKPLG 395
Cdd:COG1620  287 LKAWSPYLLLIVLLVLTRLPPPVKALLNSTTLKIPwpglLGAGTTGASYSFNPLYAPGTAILLAALITILLLRMSPGQAK 366
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 396 KALGESTKTLIGAGFVLVFTIPMVRIFINSGingadlasMPVTTANFASGLVGDAFPMLSAAIGALGAFIAGSNTVSNMM 475
Cdd:COG1620  367 RAFKETLKQLRGPILTLAFVLALAYVMNYSG--------MPATLGLALAAATGAAFPFFAPFLGWLGVFITGSDTSSNAL 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 476 FSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLPTIYYLLAAGVIGMVAIYGL 555
Cdd:COG1620  439 FGGLQFTTAEQLGLSPTLIVAAQSVGGVMGKMISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
5-547 8.53e-91

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 288.51  E-value: 8.53e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627    5 LLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITV-SVLWIVFGAIFLLNTLK 83
Cdd:pfam02652   1 LSALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLwPIAWIIIAAIFLYKISV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   84 HTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGAVGT 163
Cdd:pfam02652  81 KSGAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  164 PIIVGVNKGLDTHNIgqalvengstweiylqqITSSVAIIHAIVGILMPVLMAMMLTRFFGKNKSWtegldilPFAIFAG 243
Cdd:pfam02652 161 PITAGAGATGLSALE-----------------ISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETF-------PAVLVSG 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  244 LAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSPENEwpaewlgslkmDLNENAGKPMNLALAW 323
Cdd:pfam02652 217 LSFAIPQFLSSNVLGPELPSILGALVSLVITALFLK--FWQPKEIFRFAGKGD-----------SGATSALRAGKIVKAW 283
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  324 APYVLLAVVLVASRVSA-----------EFKSLLLSVNVTFSNILGETGISAAIQP---------LYLPGGILVFVALIA 383
Cdd:pfam02652 284 SPFVLLTAFIVLWSIPQfkalfqeggalYTSTFNFEFPEISQLIFSIPPIVGEATPfpvvfkfklLYSPGTIIFLAALLS 363
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  384 VIIQAGSAKPLGKALGESTKTLIGAGFVLVFTIPMVRIFINSGIngadLASMPVTTANfasglVGDAFPMLSAAIGALGA 463
Cdd:pfam02652 364 IFILKVSSSDALSIFKETLKEMALPIITIIFVLAFANLMNYSGM----SKTLALALAH-----TGSAFTFFSPFLGWLGV 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  464 FIAGSNTVSNMMFSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLPTIYYLLA 543
Cdd:pfam02652 435 FLTGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMGKMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAII 514

                  ....
gi 491648627  544 AGVI 547
Cdd:pfam02652 515 VGVV 518
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
1-553 1.35e-89

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 285.82  E-value: 1.35e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627    1 MNDTLLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITV-SVLWIVFGAIFLL 79
Cdd:TIGR00795   3 VYDWLSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLwPIAWIIIAAIFLY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   80 NTLKHTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFG 159
Cdd:TIGR00795  83 KLSVKSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  160 AVGTPIIVGVNKGLDTHNIgqalvengstweiylqqITSSVAIIHAIVGILMPVLMAMMLTRFFGKNKSWtegldilPFA 239
Cdd:TIGR00795 163 AVGIPIWAGAQATGLSALE-----------------ISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETF-------PAV 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  240 IFAGLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSPENEwpaewlgslkmDLNENAGKPMNL 319
Cdd:TIGR00795 219 LVAGLSFAIPQFLSSNYLGPELPSILGALVSLVITALFLK--FWQPKEIFRFNGKLD-----------AGEVSAHHICKI 285
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  320 ALAWAPYVLLAVVLVASRVSAeFKSLLLSVNVT--FSNILGETGISAAIQPLY------------------LPGGILVFV 379
Cdd:TIGR00795 286 VKAWSPFVLLTAFIVLWSIPP-FKALFMKGGALifSSFTFGSPGLSQHIFKLPpivnqatnfpavfkllliIATGTSILL 364
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  380 ALIAVIIQAGSakPLGKALGESTKTLIgagfvLVFTIPMVRIFINSGINGADLASMPVTTANFASGlVGDAFPMLSAAIG 459
Cdd:TIGR00795 365 AAIVSFFILRV--SISDAIGVFGETLK-----EMRLPILTIGMVLAFANVSNYSGMSKTLALALAH-TGLAFTFFSPFLG 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  460 ALGAFIAGSNTVSNMMFSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLPTIY 539
Cdd:TIGR00795 437 WLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGVMGKMISPQSIAIACAAVGLVGQESDLFRKTVKYSLI 516
                         570
                  ....*....|....
gi 491648627  540 YLLAAGVIGMVAIY 553
Cdd:TIGR00795 517 YAIIVGVVALLLAY 530
PRK10420 PRK10420
L-lactate permease; Provisional
2-553 9.51e-44

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 163.47  E-value: 9.51e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   2 NDTLLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITV-SVLWIVFGAIFLLN 80
Cdd:PRK10420  13 NIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLwPIAWIIIAAVFVYK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  81 TLKHTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA 160
Cdd:PRK10420  93 ISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGA 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 161 VGTPIIV-GVNKGLDTHNIGQalvengstweiylqqitssvaiihaIVGILMPVLMAMMLTRFFGKNKSWTEGLDILPFA 239
Cdd:PRK10420 173 MGIPILVaGQVTGIDSFEIGQ-------------------------MVGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAV 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 240 IFAGLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSpenEWPAEWLGSLKMDLNENAGKpmnL 319
Cdd:PRK10420 228 VVAGGSFAIAQYLSSNFIGPELPDIISSLVSLVCLTLFLK--RWQPVRIFRFG---DLGASQVDMTLAHTGYTAGQ---V 299
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 320 ALAWAPYVLLAVVLVASRVSAeFKSL----------LLSVNVTFSN--------ILGETGISAAIQP---LYLPGGILVF 378
Cdd:PRK10420 300 LRAWSPFLFLTATVTLWSIPP-FKALfasggalyewVINIPVPYLDklvarmppVVSEATAYAAVYKfdwFSATGTAILF 378
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 379 VALIAVIIQAGSAKPLGKALGESTKTLIgagfVLVFTIPMVRIFinsgingADLASMPVTTANFASGL--VGDAFPMLSA 456
Cdd:PRK10420 379 AALLSIVWLKMKPSDAISTFGSTLKELA----LPIYSIGMVLAF-------AFISNYSGLSSTLALALahTGHAFTFFSP 447
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 457 AIGALGAFIAGSNTVSNMMFSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLP 536
Cdd:PRK10420 448 FLGWLGVFLTGSDTSSNALFAALQATAAQQIGVSDVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKH 527
                        570
                 ....*....|....*..
gi 491648627 537 TIYYLLAAGVIGMVAIY 553
Cdd:PRK10420 528 SLIFTCMVGVITTLQAY 544
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
1-555 0e+00

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 538.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   1 MNDTLLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITVSVLWIVFGAIFLLN 80
Cdd:COG1620    1 MSLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGLPILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  81 TLKHTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA 160
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 161 VGTPIIVGVN-KGLDTHNIGQalvengstweiylqqitsSVAIIHAIVGILMPVLMAMMLTRFfgknKSWTEgldILPFA 239
Cdd:COG1620  161 VGTPIIVGAQvTGLDALEIGA------------------MVGRQLPILSLLIPFLLVWILDGW----RGIKE---VWPAA 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 240 IFAGLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSPENEWPAEwlgslkmDLNENAGKPMNL 319
Cdd:COG1620  216 LVAGLSFAVPQFLTANFLGPELPDIIAGLVGLAALVLFLR--FWKPKEIWDFAPEEEWPAE-------EEDAEKLSAMSL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 320 ALAWAPYVLLAVVLVASRVSAEFKSLLLSVNVTFS----NILGETGISAAIQPLYLPGGILVFVALIAVIIQAGSAKPLG 395
Cdd:COG1620  287 LKAWSPYLLLIVLLVLTRLPPPVKALLNSTTLKIPwpglLGAGTTGASYSFNPLYAPGTAILLAALITILLLRMSPGQAK 366
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 396 KALGESTKTLIGAGFVLVFTIPMVRIFINSGingadlasMPVTTANFASGLVGDAFPMLSAAIGALGAFIAGSNTVSNMM 475
Cdd:COG1620  367 RAFKETLKQLRGPILTLAFVLALAYVMNYSG--------MPATLGLALAAATGAAFPFFAPFLGWLGVFITGSDTSSNAL 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 476 FSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLPTIYYLLAAGVIGMVAIYGL 555
Cdd:COG1620  439 FGGLQFTTAEQLGLSPTLIVAAQSVGGVMGKMISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
5-547 8.53e-91

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 288.51  E-value: 8.53e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627    5 LLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITV-SVLWIVFGAIFLLNTLK 83
Cdd:pfam02652   1 LSALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLwPIAWIIIAAIFLYKISV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   84 HTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGAVGT 163
Cdd:pfam02652  81 KSGAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  164 PIIVGVNKGLDTHNIgqalvengstweiylqqITSSVAIIHAIVGILMPVLMAMMLTRFFGKNKSWtegldilPFAIFAG 243
Cdd:pfam02652 161 PITAGAGATGLSALE-----------------ISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETF-------PAVLVSG 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  244 LAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSPENEwpaewlgslkmDLNENAGKPMNLALAW 323
Cdd:pfam02652 217 LSFAIPQFLSSNVLGPELPSILGALVSLVITALFLK--FWQPKEIFRFAGKGD-----------SGATSALRAGKIVKAW 283
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  324 APYVLLAVVLVASRVSA-----------EFKSLLLSVNVTFSNILGETGISAAIQP---------LYLPGGILVFVALIA 383
Cdd:pfam02652 284 SPFVLLTAFIVLWSIPQfkalfqeggalYTSTFNFEFPEISQLIFSIPPIVGEATPfpvvfkfklLYSPGTIIFLAALLS 363
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  384 VIIQAGSAKPLGKALGESTKTLIGAGFVLVFTIPMVRIFINSGIngadLASMPVTTANfasglVGDAFPMLSAAIGALGA 463
Cdd:pfam02652 364 IFILKVSSSDALSIFKETLKEMALPIITIIFVLAFANLMNYSGM----SKTLALALAH-----TGSAFTFFSPFLGWLGV 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  464 FIAGSNTVSNMMFSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLPTIYYLLA 543
Cdd:pfam02652 435 FLTGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMGKMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAII 514

                  ....
gi 491648627  544 AGVI 547
Cdd:pfam02652 515 VGVV 518
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
1-553 1.35e-89

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 285.82  E-value: 1.35e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627    1 MNDTLLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITV-SVLWIVFGAIFLL 79
Cdd:TIGR00795   3 VYDWLSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLwPIAWIIIAAIFLY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   80 NTLKHTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFG 159
Cdd:TIGR00795  83 KLSVKSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  160 AVGTPIIVGVNKGLDTHNIgqalvengstweiylqqITSSVAIIHAIVGILMPVLMAMMLTRFFGKNKSWtegldilPFA 239
Cdd:TIGR00795 163 AVGIPIWAGAQATGLSALE-----------------ISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETF-------PAV 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  240 IFAGLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSPENEwpaewlgslkmDLNENAGKPMNL 319
Cdd:TIGR00795 219 LVAGLSFAIPQFLSSNYLGPELPSILGALVSLVITALFLK--FWQPKEIFRFNGKLD-----------AGEVSAHHICKI 285
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  320 ALAWAPYVLLAVVLVASRVSAeFKSLLLSVNVT--FSNILGETGISAAIQPLY------------------LPGGILVFV 379
Cdd:TIGR00795 286 VKAWSPFVLLTAFIVLWSIPP-FKALFMKGGALifSSFTFGSPGLSQHIFKLPpivnqatnfpavfkllliIATGTSILL 364
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  380 ALIAVIIQAGSakPLGKALGESTKTLIgagfvLVFTIPMVRIFINSGINGADLASMPVTTANFASGlVGDAFPMLSAAIG 459
Cdd:TIGR00795 365 AAIVSFFILRV--SISDAIGVFGETLK-----EMRLPILTIGMVLAFANVSNYSGMSKTLALALAH-TGLAFTFFSPFLG 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  460 ALGAFIAGSNTVSNMMFSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLPTIY 539
Cdd:TIGR00795 437 WLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGVMGKMISPQSIAIACAAVGLVGQESDLFRKTVKYSLI 516
                         570
                  ....*....|....
gi 491648627  540 YLLAAGVIGMVAIY 553
Cdd:TIGR00795 517 YAIIVGVVALLLAY 530
PRK10420 PRK10420
L-lactate permease; Provisional
2-553 9.51e-44

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 163.47  E-value: 9.51e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   2 NDTLLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITV-SVLWIVFGAIFLLN 80
Cdd:PRK10420  13 NIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLwPIAWIIIAAVFVYK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  81 TLKHTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA 160
Cdd:PRK10420  93 ISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGA 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 161 VGTPIIV-GVNKGLDTHNIGQalvengstweiylqqitssvaiihaIVGILMPVLMAMMLTRFFGKNKSWTEGLDILPFA 239
Cdd:PRK10420 173 MGIPILVaGQVTGIDSFEIGQ-------------------------MVGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAV 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 240 IFAGLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKkgFLVPKSQWDFSpenEWPAEWLGSLKMDLNENAGKpmnL 319
Cdd:PRK10420 228 VVAGGSFAIAQYLSSNFIGPELPDIISSLVSLVCLTLFLK--RWQPVRIFRFG---DLGASQVDMTLAHTGYTAGQ---V 299
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 320 ALAWAPYVLLAVVLVASRVSAeFKSL----------LLSVNVTFSN--------ILGETGISAAIQP---LYLPGGILVF 378
Cdd:PRK10420 300 LRAWSPFLFLTATVTLWSIPP-FKALfasggalyewVINIPVPYLDklvarmppVVSEATAYAAVYKfdwFSATGTAILF 378
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 379 VALIAVIIQAGSAKPLGKALGESTKTLIgagfVLVFTIPMVRIFinsgingADLASMPVTTANFASGL--VGDAFPMLSA 456
Cdd:PRK10420 379 AALLSIVWLKMKPSDAISTFGSTLKELA----LPIYSIGMVLAF-------AFISNYSGLSSTLALALahTGHAFTFFSP 447
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 457 AIGALGAFIAGSNTVSNMMFSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTVLP 536
Cdd:PRK10420 448 FLGWLGVFLTGSDTSSNALFAALQATAAQQIGVSDVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKH 527
                        570
                 ....*....|....*..
gi 491648627 537 TIYYLLAAGVIGMVAIY 553
Cdd:PRK10420 528 SLIFTCMVGVITTLQAY 544
PRK09695 PRK09695
glycolate permease GlcA;
5-553 5.42e-34

glycolate permease GlcA;


Pssm-ID: 182032  Cd Length: 560  Bit Score: 135.96  E-value: 5.42e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627   5 LLALVAFSPIVVAAILLVGLNWPAKKAMPVAFGLTVVIAIGFWDMSANRVLASVFQGLGITV-SVLWIVFGAIFLLNTLK 83
Cdd:PRK09695  16 LSALVALIPIIFFFVALAVLRLKGHVAGAITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLwPIAWIIVAAVFLYKLTV 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627  84 HTGAITTIRNGFTNISGDRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGAVGT 163
Cdd:PRK09695  96 ASGQFDIIRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLCLIANTAPVAFGALGV 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 164 PIIV-GVNKGLDTHNIGqalvengstweiylqqitSSVAIIHAIVGILMPVLMAMMLTRFFGKNKSWtegldilPFAIFA 242
Cdd:PRK09695 176 PILVaGQVTGIDPFHIG------------------AMAGRQLPFLSVLVPFWLVAMMDGWKGVKETW-------PAALVA 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 243 GLAFTVPYALTGVFLGPEFPSLIGGLFGLAIVVTAAKKgflvpksqwdFSPENEWPAEWLGSLKMDLNEN---AGKPM-- 317
Cdd:PRK09695 231 GGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKV----------WRPKNTETAISMGQSAGAMVVNkpsSGGPVps 300
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 318 -----NLALAWAPYVLLAvVLVASRVSAEFKSLLLSVNVTFS------------NILGETGISAAIQPL--------YLP 372
Cdd:PRK09695 301 eyslgQIIRAWSPFLILT-VLVTIWTMKPFKALFAPGGAFYSlvinfqiphlhqQVLKAAPIVAQPTPMdavfkfdpLSA 379
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 373 GGILVFVALIAVIIQAGSAkpLGKALGESTKTLIGAGFVlVFTIPMVRIFINSgingADLASMPVTTANFASGlVGDAFP 452
Cdd:PRK09695 380 GGTAIFIAAIISIFILGVG--IKKGIGVFAETLISLKWP-ILSIGMVLAFAFV----TNYSGMSTTLALVLAG-TGVMFP 451
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491648627 453 MLSAAIGALGAFIAGSNTVSNMMFSQFQFEVAQTLGISSVIIIALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRK 532
Cdd:PRK09695 452 FFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMISPQSIAVACAATGMVGRESELFRY 531
                        570       580
                 ....*....|....*....|.
gi 491648627 533 TVLPTIYYLLAAGVIGMVAIY 553
Cdd:PRK09695 532 TVKHSLIFASVIGIITLLQAY 552
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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