|
Name |
Accession |
Description |
Interval |
E-value |
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
7-428 |
4.09e-120 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 356.91 E-value: 4.09e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 7 FPQSFFSRTLWLV----LIVVLFSKALTLVY------------------LLMNEDVLVDRQYSHGVALtLRAYWAADEND 64
Cdd:PRK09467 4 SPRSSFARTLLLIvtllFISQVVSYLVVLNYailpslqqfnkvlayevrLLFTDQLEDGTQLVVPPAF-RREIYRELGIS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 65 --REAIAEAAGLirvvgggvpegEQHWPYSEIYQrQMQAELGADTEVRLRVHAP-PALWVRAPSLGDGWLKVPLYPHplr 141
Cdd:PRK09467 83 lySNEAAEEAGL-----------RWAQHYEFLSE-QMSQQLGGPTEVRVEVGKEsPIVWIKTPLAPNIWVRVPLTEI--- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 142 GQKIWSVLGWF-LAIGLLSTASAWIFVRQLNQPLKRLVFAARQLGQGR-SVRLPVSDTpSEMTEVYRAFNQMAEDVEQAG 219
Cdd:PRK09467 148 HQGDFSPLFRYtLAIGLLSVAGGWLFIRIQNRPLVALEHAALQVGKGEiPPPLREYGA-SEVRSVTRAFNQMAAGIKQLE 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 220 QERELMLAGVSHDLRTPLTRLRLSLELMN--DNEFSEGMVRDIEDMDAILDQFLAFIRDGRDEEIEEVDLGDLVRDVVAP 297
Cdd:PRK09467 227 DDRTLLMAGVSHDLRTPLTRIRLATEMMSeeDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNALLGEVIAA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 298 FNNAEGSIRLCLEPIP-PFPLRRVSMKRLLTNLIGNA-RHhaGNG-IEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDT 374
Cdd:PRK09467 307 ESGYEREIETALQPGPiEVPMNPIAIKRALANLVVNAaRY--GNGwIKVSSGTEGKR----AWFQVEDDGPGIPPEQLKH 380
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 492150692 375 IFNPFIRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLG 428
Cdd:PRK09467 381 LFQPFTRGDSARGSSGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLPLT 434
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
207-427 |
4.46e-55 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 182.80 E-value: 4.46e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 207 AFNQMAEDVEQAGQERELMLAGVSHDLRTPLTRLRLSLELMNDN---------EFSEGMVRDIEDMDAILDQFLAFIRDG 277
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEedlspeerrELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 278 RDE---EIEEVDLGDLVRDVVAPFNN--AEGSIRL---CLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNGIEVaaYVSG 349
Cdd:COG2205 81 SGKlslELEPVDLAELLEEAVEELRPlaEEKGIRLeldLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTI--TISA 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492150692 350 DRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:COG2205 159 RREGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPL 236
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
153-428 |
5.56e-55 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 185.50 E-value: 5.56e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 153 LAIGLLSTASAWIFVRQLNQPLKRLVFAARQLGQGRSVRLPVSDTPSEMTEVYRAFNQMAEDVEQAGQERELMLAGVSHD 232
Cdd:COG0642 41 LLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 233 LRTPLTRLRLSLELMNDN------EFSEGMVRDIEDMDAILDQFLAFIR---DGRDEEIEEVDLGDLVRDVVAPFNN--A 301
Cdd:COG0642 121 LRTPLTAIRGYLELLLEEldeeqrEYLETILRSADRLLRLINDLLDLSRleaGKLELEPEPVDLAELLEEVVELFRPlaE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 302 EGSIRLCLE---PIPPFPLRRVSMKRLLTNLIGNARHHAGNG--IEVAAYVSGDrnapYVVLSVLDRGAGIDPSELDTIF 376
Cdd:COG0642 201 EKGIELELDlpdDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGgtVTVSVRREGD----RVRISVEDTGPGIPPEDLERIF 276
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 492150692 377 NPFIRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLG 428
Cdd:COG0642 277 EPFFRTDPSRRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPLA 328
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
94-427 |
7.51e-50 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 173.59 E-value: 7.51e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 94 IYQRQMQAELGADTEVRLRVHAPPALWVRAPSLGDGWLKVPLYPHPLRGQKIWSVLGWFLAIGLLSTASAWIFVRQLNQP 173
Cdd:COG5002 34 LLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLIL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 174 LKRLVFAARQLGQGRSVRLPVSDTPSEMTEVYRAFNQMAEDV---EQAGQERELMLAGVSHDLRTPLTRLRLSLELMNDN 250
Cdd:COG5002 114 LAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDItelERLEQMRREFVANVSHELRTPLTSIRGYLELLLDG 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 251 ---------EFSEGMVRDIEDMDAILDQFLAFIR---DGRDEEIEEVDLGDLVRDVVAPFNN--AEGSIRLCLEPIPPFP 316
Cdd:COG5002 194 aaddpeerrEYLEIILEEAERLSRLVNDLLDLSRlesGELKLEKEPVDLAELLEEVVEELRPlaEEKGIELELDLPEDPL 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 317 LRRVS---MKRLLTNLIGNARHHAGNGIEVaaYVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGK--GT 391
Cdd:COG5002 274 LVLGDpdrLEQVLTNLLDNAIKYTPEGGTI--TVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSREtgGT 351
|
330 340 350
....*....|....*....|....*....|....*.
gi 492150692 392 GLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:COG5002 352 GLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPL 387
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
136-433 |
3.75e-44 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 159.38 E-value: 3.75e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 136 YPHPLRgqkiWSVLGWFLAIGLLSTASAWIFVRQLNQPLKRLVFAARQLGQGR-SVRLPVsDTPSEMTEVYRAFNQMAED 214
Cdd:PRK10604 130 YLHQMR----LLDIALLALIGLSLAFPVFLWMRPHWQDMLKLEAAAQRLGDGHlAERIHF-DEGSSLERLGVAFNQMADN 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 215 VEQAGQERELMLAGVSHDLRTPLTRLRLSLElMNDNEF---SEGMVRDIEDMDAILDQFLAFIRDGRDE---EIEEVDLG 288
Cdd:PRK10604 205 INALIASKKQLIDGIAHELRTPLVRLRYRLE-MSDNLSaaeSQALNRDIGQLEALIEELLTYARLDRPQnelHLSEPDLP 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 289 DLVRDVVAPFNNAEGSIRLCLEPIPPFPLRRVS---MKRLLTNLIGNARHHAGNGIEVAAYVSGDRnapyVVLSVLDRGA 365
Cdd:PRK10604 284 AWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDmrlMERVLDNLLNNALRYAHSRVRVSLLLDGNQ----ACLIVEDDGP 359
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 366 GIDPSELDTIFNPFIRGD--RARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLGLMLPR 433
Cdd:PRK10604 360 GIPPEERERVFEPFVRLDpsRDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPVWHNLPQ 429
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-426 |
2.99e-41 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 141.82 E-value: 2.99e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNGIEVAAYVSGdrnaPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGLAIVKRI 401
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEVSSDGEG----NRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGTSGTGLGLAIVQRI 76
|
90 100
....*....|....*....|....*
gi 492150692 402 AAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:cd16950 77 SDAHGGSLTLANRAGGGLCARIELP 101
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
213-427 |
2.96e-39 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 145.88 E-value: 2.96e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 213 EDVEQAGQEREL-----MLAGVSHDLRTPLTRLRLSLELMND-------------NEFSEGMVRDIEDMDAILDQFLAFI 274
Cdd:COG5000 187 DDITELLRAERLaawgeLARRIAHEIKNPLTPIQLSAERLRRkladkleedredlERALDTIIRQVDRLKRIVDEFLDFA 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 275 RdGRDEEIEEVDLGDLVRDVVAPFNNA--EGSIRL---CLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNG--IEVAAYV 347
Cdd:COG5000 267 R-LPEPQLEPVDLNELLREVLALYEPAlkEKDIRLeldLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGgeIEVSTRR 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 348 SGDRnapyVVLSVLDRGAGIDPSELDTIFNPFIrgdrarSGK--GTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRL 425
Cdd:COG5000 346 EDGR----VRIEVSDNGPGIPEEVLERIFEPFF------TTKpkGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRL 415
|
..
gi 492150692 426 PL 427
Cdd:COG5000 416 PL 417
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
93-427 |
1.27e-35 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 134.93 E-value: 1.27e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 93 EIYQRQMQAELGADTEVRLRVHAPPALWVRAPSLGDGWLKVPLYPHPLRGQKIWSVLGWFLAIGLLSTASAWIFVRQLNQ 172
Cdd:COG4191 1 ALRLLLLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 173 PLKRLVFAARQLGQGRSVRLPVSDTPSEMTEVYRAFNQMAEDVEQAGQ-EREL-----------MLAGVSHDLRTPLTRL 240
Cdd:COG4191 81 LLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRElQEQLvqseklaalgeLAAGIAHEINNPLAAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 241 RLSLELMND-----------NEFSEGMVRDIEDMDAILDQFLAFIRdGRDEEIEEVDLGDLVRDVVA------PFNNAEg 303
Cdd:COG4191 161 LGNAELLRRrledepdpeelREALERILEGAERAAEIVRSLRAFSR-RDEEEREPVDLNELIDEALEllrprlKARGIE- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 304 sIRLCLEP-IPPFPLRRVSMKRLLTNLIGNARH---HAGNG-IEVAAYVSGDrnapYVVLSVLDRGAGIDPSELDTIFNP 378
Cdd:COG4191 239 -VELDLPPdLPPVLGDPGQLEQVLLNLLINAIDameEGEGGrITISTRREGD----YVVISVRDNGPGIPPEVLERIFEP 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 492150692 379 FI--RgdraRSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:COG4191 314 FFttK----PVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLPL 360
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
5-426 |
1.50e-34 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 134.53 E-value: 1.50e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 5 LWFPQSFFSRTLWLVLIVVLFSKALTLVYLLMNEDVLVDRQYSHGVALTLRAYWAADENDREAIAEAAGLIRVVGGGVPE 84
Cdd:COG4251 63 LLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELAL 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 85 GEQHWPYSEIYQRQMQAELGAD--TEVRLRVHAPPALWVRAPSLGDGWLKVPLYPHPLRGQKIWSVLGWFLAIGLLSTAS 162
Cdd:COG4251 143 LRLALALLLLLLLLLLLLLLLLalILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLG 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 163 AWIFVRQLNQPLKRLVFAARQLGQGRSVRLPVSDTPSEMTEVYRAFNQMAEDVEQAGQERELMLAGVSHDLRTPLTRLRL 242
Cdd:COG4251 223 GGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELERSNEELEQFAYVASHDLREPLRKISG 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 243 SLELMND----------NEFSEGMVRDIEDMDAILDQFLAFIRDGRDE-EIEEVDLGDLVRDVVAPFNN--AEGSIRLCL 309
Cdd:COG4251 303 FSQLLEEdygdkldeegREYLERIRDAAERMQALIDDLLAYSRVGRQElEFEPVDLNELLEEVLEDLEPriEERGAEIEV 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 310 EPIPPFPLRRVSMKRLLTNLIGNARHHAGNGIEVAAYVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGK 389
Cdd:COG4251 383 GPLPTVRGDPTLLRQVFQNLISNAIKYSRPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEYE 462
|
410 420 430
....*....|....*....|....*....|....*..
gi 492150692 390 GTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:COG4251 463 GTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLP 499
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
153-426 |
1.79e-34 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 134.38 E-value: 1.79e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 153 LAIGLLSTASAWIFVRQLNQPLKRLVFAARQLGQGR-SVRLPVSDTpSEMTEVYRAFNQMAEDVEQAGQERELM------ 225
Cdd:NF040691 195 LALVVLLGLIAWLVTRQVVAPVRSAARTAERFAAGDlSERMPVKGE-DDLARLARSFNQMADSLQRQIRQLEELsrlqqr 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 226 -LAGVSHDLRTPLTRLRLSLELMNDN--EFSEGMVRDIEDMDAILDQFLAFIRD---------GRDE-EIEEVDLGDLVR 292
Cdd:NF040691 274 fVSDVSHELRTPLTTIRMAADVIHDSrdDFDPATARSAELLHTELDRFESLLSDlleisrfdaGAAElDVEPVDLRPLVR 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 293 DVV------APFNNAEGSIRLCLEP-IPPFPLRRVsmKRLLTNLIGNARHHaGNGIEVAAYVSGDRNApyVVLSVLDRGA 365
Cdd:NF040691 354 RVVdalrqlAERAGVELRVDAPGTPvVAEVDPRRV--ERVLRNLVVNAIEH-GEGKPVVVTVAQDDTA--VAVTVRDHGV 428
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492150692 366 GIDPSELDTIFNPFIRGD--RARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:NF040691 429 GLKPGEVALVFDRFWRADpaRARTTGGTGLGLAIALEDARLHGGWLEAWGRPGQGSQFRLTLP 491
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
183-427 |
6.14e-32 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 124.57 E-value: 6.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 183 QLGQGRSVRLPVSDTPSEMTEVYRAFNQMAEDVEQAGQ-EREL-----------MLAGVSHDLRTPLTRLRLSLELM--- 247
Cdd:COG3852 84 RRKDGEERPVDVSVSPLRDAEGEGGVLLVLRDITERKRlERELrraeklaavgeLAAGLAHEIRNPLTGIRGAAQLLere 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 248 ----NDNEFSEGMVRDIEDMDAILDQFLAFIRdGRDEEIEEVDLGDLVRDVVAPFNNAEGS---IRLCLEP-IPPFPLRR 319
Cdd:COG3852 164 lpddELREYTQLIIEEADRLNNLVDRLLSFSR-PRPPEREPVNLHEVLERVLELLRAEAPKnirIVRDYDPsLPEVLGDP 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 320 VSMKRLLTNLIGNARHHAGNG--IEVAAYV------SGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGdrarSGKGT 391
Cdd:COG3852 243 DQLIQVLLNLVRNAAEAMPEGgtITIRTRVerqvtlGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTT----KEKGT 318
|
250 260 270
....*....|....*....|....*....|....*.
gi 492150692 392 GLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:COG3852 319 GLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPL 354
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
138-410 |
2.33e-31 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 124.81 E-value: 2.33e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 138 HPLRGQKIWSVLGWFLAIgLLSTASAWIFVRQLNQPLKRLVFAARQLGQGR-SVRLPVSDTPSEMTEVYRAFNQMAEDVE 216
Cdd:TIGR01386 157 HLLDALRKWLILIAVLLV-LLTALLGWWITRLGLEPLRRLSAVAARISPESlDQRLDPSRAPAELRELAQSFNAMLGRLE 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 217 QAGQERELMLAGVSHDLRTPLTRL------RLSLE---------LMNDNEFSEGMVRDIEDMdaildQFLAFIRDGRDE- 280
Cdd:TIGR01386 236 DAFQRLSQFSADLAHELRTPLTNLlgqtqvALSQPrtgeeyrevLESNLEELERLSRMVSDM-----LFLARADNGQLAl 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 281 EIEEVDLGDLVRDVVAPFN--NAEGSIRLCLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNGIEVAayVSGDRNAPYVVL 358
Cdd:TIGR01386 311 ERVRLDLAAELAKVAEYFEplAEERGVRIRVEGEGLVRGDPQMFRRAISNLLSNALRHTPDGGTIT--VRIERRSDEVRV 388
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 492150692 359 SVLDRGAGIDPSELDTIFNPFIRGDRARSGK--GTGLGLAIVKRIAAMHGGNVE 410
Cdd:TIGR01386 389 SVSNPGPGIPPEHLSRLFDRFYRVDPARSNSgeGTGLGLAIVRSIMEAHGGRAS 442
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
199-427 |
1.07e-30 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 124.31 E-value: 1.07e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 199 SEMTEVYRAFNQMAEdveqagQER-----ELMlAGVSHDLRTPLTRLRLSLELMNDN-------EFSEGMVRDIEDMDAI 266
Cdd:PRK11360 369 SDLTERKRLQRRVAR------QERlaalgELV-AGVAHEIRNPLTAIRGYVQIWRQQtsdppsqEYLSVVLREVDRLNKV 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 267 LDQFLAFIRDgRDEEIEEVDLGDLVRDVVAPFNNAEGS----IRLCLEP-IPPFPLRRVSMKRLLTNLIGNARHHAGNG- 340
Cdd:PRK11360 442 IDQLLEFSRP-RESQWQPVSLNALVEEVLQLFQTAGVQarvdFETELDNeLPPIWADPELLKQVLLNILINAVQAISARg 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 341 -IEVAAYVSGDRNapyVVLSVLDRGAGIDPSELDTIFNPFIrgdrARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGL 419
Cdd:PRK11360 521 kIRIRTWQYSDGQ---VAVSIEDNGCGIDPELLKKIFDPFF----TTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGT 593
|
....*...
gi 492150692 420 EARVRLPL 427
Cdd:PRK11360 594 TFTLYLPI 601
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
143-428 |
3.66e-30 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 121.49 E-value: 3.66e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 143 QKIWSVLGWFLAIGLLSTA--SAWifvrqLNQPLKRLVFAARQLGQGRSVRLPVSdTPSEMTEVYRAFNQM--------- 211
Cdd:PRK11100 182 RRILWAGALLLGIALLIGAgvVWW-----LNRSIRRLTRYADAVTEGKPVPLPKL-GSSELRELAQALESMrvklegkay 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 212 AEDVEQAgqerelmlagVSHDLRTPLTRLRLSLELMNDN-------EFSEGMVRDIEDMDAILDQFLAFIR---DGRDEE 281
Cdd:PRK11100 256 VEQYVQT----------LTHELKSPLAAIRGAAELLQEDpppedraRFTGNILTQSARLQQLIDRLLELARleqRQELEV 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 282 IEEVDLGDLVRDVVAPFNN--AEGSIRLCLEPIP------PFPLRRVsmkrlLTNLIGNARHHAGNGIEVAayVSGDRNA 353
Cdd:PRK11100 326 LEPVALAALLEELVEAREAqaAAKGITLRLRPDDarvlgdPFLLRQA-----LGNLLDNAIDFSPEGGTIT--LSAEVDG 398
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492150692 354 PYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSG-KGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLG 428
Cdd:PRK11100 399 EQVALSVEDQGPGIPDYALPRIFERFYSLPRPANGrKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPRH 474
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
322-425 |
6.06e-30 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 111.93 E-value: 6.06e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNG--IEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGLAIVK 399
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGgtIEISLRQEGDG----VVLEVEDNGPGIPEEDLERIFERFYRGDKSREGGGTGLGLAIVR 76
|
90 100
....*....|....*....|....*.
gi 492150692 400 RIAAMHGGNVELRNRSGGGLEARVRL 425
Cdd:cd00075 77 RIVEAHGGRITVESEPGGGTTFTVTL 102
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
153-427 |
1.63e-28 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 116.96 E-value: 1.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 153 LAIGLLSTASAWIFVRQLNQPLKRLVFAARQLGQGRSVRLPVSDT-PSEMTEVYRAFNQMAEDVEQ--AGQERelMLAGV 229
Cdd:PRK09470 173 LVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELETgPQEFRQAGASFNQMVTALERmmTSQQR--LLSDI 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 230 SHDLRTPLTRLRLSLELM--NDNEFSEgMVR---DIEDMDAILDQFLAFIRDGRDEEI--EEVDLGDLVRDVV--APFNN 300
Cdd:PRK09470 251 SHELRTPLTRLQLATALLrrRQGESKE-LERietEAQRLDSMINDLLVLSRNQQKNHLerETFKANSLWSEVLedAKFEA 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 301 AEGSIRLCLEPIP-PFPL--RRVSMKRLLTNLIGNARHHAGNGIEVAAYVSGDrnapYVVLSVLDRGAGIDPSELDTIFN 377
Cdd:PRK09470 330 EQMGKSLTVSAPPgPWPIngNPNALASALENIVRNALRYSHTKIEVAFSVDKD----GLTITVDDDGPGVPEEEREQIFR 405
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 492150692 378 PFIRGDRAR---SGkGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:PRK09470 406 PFYRVDEARdreSG-GTGLGLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLPL 457
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
322-427 |
7.01e-28 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 106.58 E-value: 7.01e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNGIEVAayVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGD-RARSGKGTGLGLAIVKR 400
Cdd:smart00387 6 LRQVLSNLLDNAIKYTPEGGRIT--VTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDkRSRKIGGTGLGLSIVKK 83
|
90 100
....*....|....*....|....*..
gi 492150692 401 IAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:smart00387 84 LVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
225-435 |
2.21e-25 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 108.14 E-value: 2.21e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 225 MLAGVSHDLRTPLTRLRLSLELMNDNEFSEG------MVRDIEDMDAILDQFLAFIRDgRDEEIEEVDLGDLVRDVVaPF 298
Cdd:COG5809 273 LAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQktyldiMLSELDRIESIISEFLVLAKP-QAIKYEPKDLNTLIEEVI-PL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 299 NNAEG-----SIRL-CLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNG----IEVAAYvsgDRNapYVVLSVLDRGAGID 368
Cdd:COG5809 351 LQPQAllknvQIELeLEDDIPDILGDENQLKQVFINLLKNAIEAMPEGgnitIETKAE---DDD--KVVISVTDEGCGIP 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492150692 369 PSELDTIFNPFIrgdrARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLGLMLPRDA 435
Cdd:COG5809 426 EERLKKLGEPFY----TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPIKLSEQVSM 488
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
324-427 |
5.26e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 95.86 E-value: 5.26e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 324 RLLTNLIGNARHHAGNGIEVAAYVSGDrnapYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGK--GTGLGLAIVKRI 401
Cdd:cd16949 3 RALENVLRNALRYSPSKILLDISQDGD----QWTITITDDGPGVPEDQLEQIFLPFYRVDSARDREsgGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 492150692 402 AAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
319-427 |
2.16e-23 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 94.36 E-value: 2.16e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 319 RVSMKRLLTNLIGNARHHAGNGIEVAAYVSGDRNapyVVLSVLDRGAGIDPSELDTIFNPFIRGDRaRSGKGTGLGLAIV 398
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHAAKAGEITVTLSEGGE---LTLTVEDNGIGIPPEDLPRIFEPFSTADK-RGGGGTGLGLSIV 78
|
90 100
....*....|....*....|....*....
gi 492150692 399 KRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:pfam02518 79 RKLVELLGGTITVESEPGGGTTVTLTLPL 107
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
164-426 |
3.49e-23 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 100.04 E-value: 3.49e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 164 WIFVRQLNQPLKRLvfaARQLgQGRSVR----LPVSDTPSEMTEVYRAFNQMAEDVEQAGQERELMLAGVSHDLRTPLTR 239
Cdd:PRK10755 79 FQAVRWITRPLAEL---QKEL-EARTADnltpIAIHSSTLEIEAVTSALNQLVSRLTSTLDQERLFTADVAHELRTPLAG 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 240 LRLSLELMNDNEFSEGM--VRDIEDMDAILDQFLAFIRDGRDEEIEEVDLGDLVRDVVAPfnnAEGSIRLCLE------- 310
Cdd:PRK10755 155 IRLHLELLEKQHHIDVAplIARLDQMMHTVEQLLQLARAGQSFSSGHYQTVKLLEDVILP---SQDELSEMLEqrqqtll 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 311 -PIPPFPLR----RVSMKRLLTNLIGNARHHAGNGIEVAAYVSGDrnAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRa 385
Cdd:PRK10755 232 lPESAADITvqgdATLLRLLLRNLVENAHRYSPEGSTITIKLSQE--DGGAVLAVEDEGPGIDESKCGELSKAFVRMDS- 308
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 492150692 386 RSGkGTGLGLAIVKRIAAMHGGNVELRNRS-GGGLEARVRLP 426
Cdd:PRK10755 309 RYG-GIGLGLSIVSRITQLHHGQFFLQNRQeRSGTRAWVWLP 349
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
218-427 |
4.39e-22 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 98.27 E-value: 4.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 218 AGQerelMLAGVSHDLRTPLTRLRLSLELM-----NDNEFSEGMVRDIEDMDAILDQFLAFIRDGRDEeIEEVDLGDLVR 292
Cdd:COG5805 287 AGQ----LAAGIAHEIRNPLTSIKGFLQLLqpgieDKEEYFDIMLSELDRIESIISEFLALAKPQAVN-KEKENINELIQ 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 293 DVVaPFNNAEG-----SIRL-CLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNG--IEVAAYVSGDrnapYVVLSVLDRG 364
Cdd:COG5805 362 DVV-TLLETEAilhniQIRLeLLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGgtITIHTEEEDN----SVIIRVIDEG 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492150692 365 AGIDPSELDTIFNPFIrgdrARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:COG5805 437 IGIPEERLKKLGEPFF----TTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
157-435 |
1.42e-21 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 96.63 E-value: 1.42e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 157 LLSTASAWIFVRQLNQPLKRLVFAARQLGQGR-SVRLPVSDTpSEMTEVYRAFNQMAEDVEQAGQERELMLAGVSHDLRT 235
Cdd:PRK10549 175 LLAALATFLLARGLLAPVKRLVEGTHKLAAGDfTTRVTPTSR-DELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRT 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 236 PLTRLRLSLELMND--NEFSEGMVRDIEDMDAILDQF--------------LAFIRdgrdeeiEEVDLGDLVRDVVAPFN 299
Cdd:PRK10549 254 PLAVLRGELEAIQDgvRKFTPESVASLQAEVGTLTKLvddlhqlslsdegaLAYRK-------TPVDLVPLLEVAGGAFR 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 300 N--AEGSIRLCL---EPIPPF--PLRrvsMKRLLTNLIGNA-RHHAGNGievAAYVSGDRNAPYVVLSVLDRGAGIDPSE 371
Cdd:PRK10549 327 ErfASRGLTLQLslpDSATVFgdPDR---LMQLFNNLLENSlRYTDSGG---SLHISAEQRDKTLRLTFADSAPGVSDEQ 400
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492150692 372 LDTIFNPFIR--GDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLGLMLPRDA 435
Cdd:PRK10549 401 LQKLFERFYRteGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV 466
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-425 |
2.11e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 89.00 E-value: 2.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNGIEVAAYVSGDRNApyvVLSVLDRGAGIDPSELDTIFNPFIRGDrARSGKGTGLGLAIVKRI 401
Cdd:cd16940 14 LFLLLRNLVDNAVRYSPQGSRVEIKLSADDGA---VIRVEDNGPGIDEEELEALFERFYRSD-GQNYGGSGLGLSIVKRI 89
|
90 100
....*....|....*....|....
gi 492150692 402 AAMHGGNVELRNRSGGGLEARVRL 425
Cdd:cd16940 90 VELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
211-410 |
5.25e-21 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 93.43 E-value: 5.25e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 211 MAEDV---EQAGQERELMLAGVSHDLRTPLTRLRLSLELMND---------NEFSEGMVRDIEDMDAILDQFLAFIR--- 275
Cdd:TIGR02966 100 VARDVtrlRRLEQMRRDFVANVSHELRTPLTVLRGYLETLADgpdedpeewNRALEIMLEQSQRMQSLVEDLLTLSRles 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 276 DGRDEEIEEVDLGDLVRDVVAPFN--NAEGSIRLCLEPIPPFPLR--RVSMKRLLTNLIGNARHHAGNGIEVAayVSGDR 351
Cdd:TIGR02966 180 AASPLEDEPVDMPALLDHLRDEAEalSQGKNHQITFEIDGGVDVLgdEDELRSAFSNLVSNAIKYTPEGGTIT--VRWRR 257
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492150692 352 NAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARS--GKGTGLGLAIVKRIAAMHGGNVE 410
Cdd:TIGR02966 258 DGGGAEFSVTDTGIGIAPEHLPRLTERFYRVDKSRSrdTGGTGLGLAIVKHVLSRHHARLE 318
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
151-424 |
8.12e-21 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 94.33 E-value: 8.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 151 WFLAIGLLSTASAWIFVRQLnQPLKRLVFAARQLGQGRSVRLPVSDTPSEMTEVYRAFNQMAEDVEQAGQERELMLAGVS 230
Cdd:PRK10337 167 WLVALPIMLIILMVLLGREL-APLKKLALALRMRDPDSETPLNATGVPSEVRPLVEALNQLFARTHAMMVRERRFTSDAA 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 231 HDLRTPLTRLRLSLE---LMNDNEfsegMVRD---------IEDMDAILDQFLAFIR-DGRD--EEIEEVDLGDLVRD-V 294
Cdd:PRK10337 246 HELRSPLAALKVQTEvaqLSDDDP----QARKkallqlhagIDRATRLVDQLLTLSRlDSLDnlQDVAEIPLEDLLQSaV 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 295 VAPFNNAE-GSIRLCLEpIPPFPLRRVSMKRLLT----NLIGNARHHAGNGIEVAAYVSGDRnapyvvLSVLDRGAGIDP 369
Cdd:PRK10337 322 MDIYHTAQqAGIDVRLT-LNAHPVIRTGQPLLLSllvrNLLDNAIRYSPQGSVVDVTLNARN------FTVRDNGPGVTP 394
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 492150692 370 SELDTIFNPFIR--GDRArsgKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVR 424
Cdd:PRK10337 395 EALARIGERFYRppGQEA---TGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKVS 448
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
220-428 |
6.14e-20 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 92.79 E-value: 6.14e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 220 QERELMLAGVSHDLRTPLTRLRLSLELMNDNEFSEGMvRDIEDMDAILDQFLAFIR-------------DGRDEEIEEVD 286
Cdd:PRK10490 662 QLRNALLAALSHDLRTPLTVLFGQAEILTLDLASEGS-PHARQASEIRQQVLNTTRlvnnlldmariqsGGFNLRKEWLT 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 287 LGDLVRDVVAPFNNAEGSIRLCLEPIPPFPLRRVS---MKRLLTNLIGNARHHAGNGIEVA--AYVSGDRnapyVVLSVL 361
Cdd:PRK10490 741 LEEVVGSALQMLEPGLSGHPINLSLPEPLTLIHVDgplFERVLINLLENAVKYAGAQAEIGidAHVEGER----LQLDVW 816
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492150692 362 DRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLG 428
Cdd:PRK10490 817 DNGPGIPPGQEQLIFDKFARGNKESAIPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPLE 883
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
322-427 |
4.56e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 82.16 E-value: 4.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNA-----RHHagngIEVAAYVSGDRNAPYVV-LSVLDRGAGIDPSELDTIFNPFIRGDRARSGK--GTGL 393
Cdd:cd16922 1 LRQILLNLLGNAikfteEGE----VTLRVSLEEEEEDGVQLrFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKygGTGL 76
|
90 100 110
....*....|....*....|....*....|....
gi 492150692 394 GLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:cd16922 77 GLAISKKLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-427 |
8.49e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 81.32 E-value: 8.49e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNGIEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDTIFNPFIRGD--RARSGKGTGLGLAIVK 399
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGGR----LTLIVEDDGPGIPAAARERVFEPFVRLDpsRDRATGGFGLGLAIVH 76
|
90 100
....*....|....*....|....*...
gi 492150692 400 RIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:cd16939 77 RVALWHGGHVECDDSELGGACFRLTWPR 104
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
214-407 |
1.84e-17 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 84.80 E-value: 1.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 214 DV---EQAGQERELMLAGVSHDLRTPLTRLRLSLELMNDnefseGMVRDIEdmdaILDQFLAFIR--------------- 275
Cdd:NF033092 361 DVteqEKIEQERREFVANVSHELRTPLTTMRSYLEALAD-----GAWKDPE----LAPRFLGVTQnetermirlvndllq 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 276 ----DGRDEEI--EEVDLGDLVRDVVAPF--NNAEGSIRLCLEpippFPLRRVS-------MKRLLTNLIGNARHHAGNG 340
Cdd:NF033092 432 lsrmDSKDYKLnkEWVNFNEFFNYIIDRFemILKNKNITFKRE----FPKRDLWveidtdkITQVLDNIISNAIKYSPEG 507
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492150692 341 IEVAAYVSGDRNapYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGK--GTGLGLAIVKRIAAMHGG 407
Cdd:NF033092 508 GTITFRLLETHN--RIIISISDQGLGIPKKDLDKIFDRFYRVDKARSRKmgGTGLGLAIAKEVVEAHGG 574
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
119-427 |
4.44e-17 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 83.92 E-value: 4.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 119 LWVRAPSLGDGWLKVPLYPH---------PLRGQKIWSVLGWFLAIGLLStasaWIFVRQLNQPLKRLVFAARQLGQ-GR 188
Cdd:PRK15347 265 LVLRTQLKGPGWQQVTLYPRrnlanealkPALQQLPFALLILVLLTSVLF----LLLRRYLAKPLWRFVDIINKTGPaAL 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 189 SVRLPVSDTpSEMTEVYRAFNQM---------------AE---DVEQAGQERELM-------LAGVSHDLRTPLTRLRLS 243
Cdd:PRK15347 341 EPRLPENRL-DELGSIAKAYNQLldtlneqydtlenkvAErtqALAEAKQRAEQAnkrksehLTTISHEIRTPLNGVLGA 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 244 LELMNDNEFsegmvrDIEDMD-------------AILDQFLAF--IRDGRDE-EIEEVDLGDLVRDVVAPFNNAEGSIRL 307
Cdd:PRK15347 420 LELLQNTPL------TAEQMDladtarqctlsllAIINNLLDFsrIESGQMTlSLEETALLPLLDQAMLTIQGPAQSKSL 493
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 308 CLEPI--PPFPLR----RVSMKRLLTNLIGNARHHAGNG-IEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDTIFNPFI 380
Cdd:PRK15347 494 TLRTFvgAHVPLYlhldSLRLRQILVNLLGNAVKFTETGgIRLRVKRHEQQ----LCFTVEDTGCGIDIQQQQQIFTPFY 569
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 492150692 381 RGDraRSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:PRK15347 570 QAD--THSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLPL 614
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
129-427 |
9.68e-17 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 81.99 E-value: 9.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 129 GWLKVPLYPHPLRGQKIWSVLGWFLAIG----LLSTASAWIFVRQLNQPLKRLVFAARQLGQGRSVRLPVSdTPSEMTEV 204
Cdd:COG2972 136 GWTLVSLIPKSELFRGLFSLRRLILLIIllllLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLVRLEVS-GNDEIGIL 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 205 YRAFNQMAEDVEQAGQE-RELMLAgvshdlrtpLTRLRLS-LE-------LMNdnefsegmvrdiedmdaILDQFLAFIR 275
Cdd:COG2972 215 ARSFNEMVERIKELIEEvYELELE---------KKEAELKaLQaqinphfLFN-----------------TLNSIRWLAE 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 276 DGRDEEIEEV--DLGDLVRDVVAPFNN---------------------AEGSIRLCLEpIPPFPLRRVSMKRLLTNLIGN 332
Cdd:COG2972 269 LEDPEEAEEMleALSKLLRYSLSKGDElvtleeeleliksyleiqklrFGDRLEVEIE-IDEELLDLLIPKLILQPLVEN 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 333 ARHHA-----GNG-IEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDTIFNPFirgdrARSGKGTGLGLAIV-KRIAAMH 405
Cdd:COG2972 348 AIEHGiepkeGGGtIRISIRKEGDR----LVITVEDNGVGMPEEKLEKLLEEL-----SSKGEGRGIGLRNVrERLKLYY 418
|
330 340
....*....|....*....|....
gi 492150692 406 GGN--VELRNRSGGGLEARVRLPL 427
Cdd:COG2972 419 GEEygLEIESEPGEGTTVTIRIPL 442
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
322-426 |
3.69e-16 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 74.07 E-value: 3.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNGIEVAAYVSGDRnAPYVVLSVLDRGAGIDPSELDTIFNPFIRG--DRARSGKGTGLGLAIVK 399
Cdd:cd16925 5 YERVVLNLLSNAFKFTPDGGRIRCILEKFR-LNRFLLTVSDSGPGIPPNLREEIFERFRQGdgSSTRAHGGTGLGLSIVK 83
|
90 100
....*....|....*....|....*..
gi 492150692 400 RIAAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:cd16925 84 EFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
205-427 |
1.04e-15 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 78.67 E-value: 1.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 205 YRAFNQMAEDvEQAGQERELML----AGVSHDLRTPLTRLR--------LSLELMNDNEFSEGMVRDIEDMDAILDQFLA 272
Cdd:PRK10364 217 YLRSRQLLQD-EMKRKEKLVALghlaAGVAHEIRNPLSSIKglakyfaeRAPAGGEAHQLAQVMAKEADRLNRVVSELLE 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 273 FIRDGrDEEIEEVDLGDLVRDV---VAPFNNAEGsIRLCLEPIPPFPLRRVSMKRL---LTNLIGNARHHAGNG--IEVA 344
Cdd:PRK10364 296 LVKPT-HLALQAVDLNDLINHSlqlVSQDANSRE-IQLRFTANDTLPEIQADPDRLtqvLLNLYLNAIQAIGQHgvISVT 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 345 AYVSGDRnapyVVLSVLDRGAGIDPSELDTIFNPFIrgdrARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVR 424
Cdd:PRK10364 374 ASESGAG----VKISVTDSGKGIAADQLEAIFTPYF----TTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLW 445
|
...
gi 492150692 425 LPL 427
Cdd:PRK10364 446 LPV 448
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
314-419 |
1.31e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 72.49 E-value: 1.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 314 PFPLRRVsmkrlLTNLIGNARHHAGNGIEVAayVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSG-KGTG 392
Cdd:cd16945 2 PFLLRQA-----INNLLDNAIDFSPEGGLIA--LQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGqKSTG 74
|
90 100
....*....|....*....|....*..
gi 492150692 393 LGLAIVKRIAAMHGGNVELRNRSGGGL 419
Cdd:cd16945 75 LGLAFVQEVAQLHGGRITLRNRPDGVL 101
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-418 |
1.90e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 71.97 E-value: 1.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNGIEVAAYVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGLAIVKRI 401
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSREEYEGTGVGLAIVRKI 80
|
90
....*....|....*..
gi 492150692 402 AAMHGGNVELRNRSGGG 418
Cdd:cd16921 81 IERHGGRIWLESEPGEG 97
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-427 |
2.39e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 71.80 E-value: 2.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 319 RVSMKRLLTNLIGNARHHA----GNGIEVAAYVSGDRNAPyVVLSVLDRGAGIDPSELDTIFNPFIrgdrARSGKGTGLG 394
Cdd:cd16944 2 TTQISQVLTNILKNAAEAIegrpSDVGEVRIRVEADQDGR-IVLIVCDNGKGFPREMRHRATEPYV----TTRPKGTGLG 76
|
90 100 110
....*....|....*....|....*....|...
gi 492150692 395 LAIVKRIAAMHGGNVELRNRSGGGleARVRLPL 427
Cdd:cd16944 77 LAIVKKIMEEHGGRISLSNREAGG--ACIRIIL 107
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-427 |
2.56e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 71.30 E-value: 2.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 319 RVSMKRLLTNLIGNARHhAGNG---IEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDTIFNPFIRGDRArsGKGTGLGL 395
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQ-AMEGrgrITIRTWAHVDQ----VLIEVEDTGSGIDPEILGRIFDPFFTTKPV--GEGTGLGL 73
|
90 100 110
....*....|....*....|....*....|..
gi 492150692 396 AIVKRIAAMHGGNVELRNRSGGGLEARVRLPL 427
Cdd:cd16943 74 SLSYRIIQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
153-409 |
6.39e-15 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 76.35 E-value: 6.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 153 LAIGLLSTASAWIFVRQLNQPLKRLVFAARQL-GQGRSVRLPVSDTPSEMTEVYRAFNQMAEDVEQAGQERELMLAGVSH 231
Cdd:PRK09835 192 SVISLLIVFIVLLAVHKGHAPIRSVSRQIQNItSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAH 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 232 DLRTPLTRLRLSLELM-----NDNEFSEGMVRDIED---MDAILDQFLAFIRDGRDEEIEEVDLGDLVRDVVAPFN---- 299
Cdd:PRK09835 272 EIRTPITNLITQTEIAlsqsrSQKELEDVLYSNLEEltrMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKVFDffea 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 300 -NAEGSIRL------CLEPIPPFPLRRVsmkrlLTNLIGNARHHAGNGIEVAAYVSGDRNApyVVLSVLDRGAGIDPSEL 372
Cdd:PRK09835 352 wAEERGVELrfvgdpCQVAGDPLMLRRA-----ISNLLSNALRYTPAGEAITVRCQEVDHQ--VQLVVENPGTPIAPEHL 424
|
250 260 270
....*....|....*....|....*....|....*....
gi 492150692 373 DTIFNPFIRGD--RARSGKGTGLGLAIVKRIAAMHGGNV 409
Cdd:PRK09835 425 PRLFDRFYRVDpsRQRKGEGSGIGLAIVKSIVVAHKGTV 463
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
201-427 |
7.90e-15 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 75.67 E-value: 7.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 201 MTEVYRAFNQM--AEDVEQAGQerelMLAGVSHDLRTPLTRLRLSLELMNDNEFSEGMVRD-----IEDMD---AILDQF 270
Cdd:COG5806 182 LIENILLRKELqrAEKLEVVSE----LAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQyiriaLEELDraeAIITDY 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 271 LAFIRDgRDEEIEEVDLGDLVRDVV---APFNNAEGsIRLCLEPIPPFPLR--RVSMKRLLTNLIGNARHHAGNGIEVAA 345
Cdd:COG5806 258 LTFAKP-QPEKLEKIDVSEELEHVIdvlSPYANMNN-VEIQTELEPGLYIEgdRQKLQQCLINIIKNGIEAMPNGGTLTI 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 346 YVSGDRNapYVVLSVLDRGAGIDPSELDTIFNPFIrgdrARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRL 425
Cdd:COG5806 336 DVSIDKN--KVIISIKDTGVGMTKEQLERLGEPYF----STKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITL 409
|
..
gi 492150692 426 PL 427
Cdd:COG5806 410 PL 411
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
305-428 |
8.10e-15 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 75.66 E-value: 8.10e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 305 IRLCLEP---IPPFPLRRVSMKRLLTNLIGNARHHAGNG------IEVAAYVSGDrnapYVVLSVLDRGAGIDPSELDTI 375
Cdd:COG3290 262 IDLTIDIdsdLPDLPLSDTDLVTILGNLLDNAIEAVEKLpeeerrVELSIRDDGD----ELVIEVEDSGPGIPEELLEKI 337
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 492150692 376 FNpfiRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLG 428
Cdd:COG3290 338 FE---RGFSTKLGEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLPKE 387
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
210-427 |
1.16e-14 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 76.17 E-value: 1.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 210 QMAEDVEQAGQERELMLAGVSHDLRTPLTRLRLSLELMNDNEFSEGMVRDIEDMDAILDQFLAFIRDGRD-EEIEEVDLG 288
Cdd:PRK10841 435 EMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLVTAMNNSSSLLLKIISDILDfSKIESEQLK 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 289 DLVRdvvaPFNNAE--GSI-----------RLCL----EPIPPFPLRR--VSMKRLLTNLIGNARH--HAGnGIEVAAYV 347
Cdd:PRK10841 515 IEPR----EFSPREviNHItanylplvvkkRLGLycfiEPDVPVALNGdpMRLQQVISNLLSNAIKftDTG-CIVLHVRV 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 348 SGDrnapYVVLSVLDRGAGIDPSELDTIFNPF--IRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRL 425
Cdd:PRK10841 590 DGD----YLSFRVRDTGVGIPAKEVVRLFDPFfqVGTGVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRI 665
|
..
gi 492150692 426 PL 427
Cdd:PRK10841 666 PL 667
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
212-432 |
3.97e-14 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 73.89 E-value: 3.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 212 AEDVEQAGQ---ERELMLAGVSHDLRTPLTRLRLSLELMNDNEFsEGMVRD---------IEDMDAILDQFLAF--IRDG 277
Cdd:PRK11006 191 ARDVTQMHQlegARRNFFANVSHELRTPLTVLQGYLEMMQDQPL-EGALREkalhtmreqTQRMEGLVKQLLTLskIEAA 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 278 RDEEIEE-VD----LGDLVRDVVAPFNNAEgSIRLCLEPippfpLRRV-----SMKRLLTNLIGNARHHAGNGIEVAayV 347
Cdd:PRK11006 270 PTIDLNEkVDvpmmLRVLEREAQTLSQGKH-TITFEVDN-----SLKVfgnedQLRSAISNLVYNAVNHTPEGTHIT--V 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 348 SGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGK--GTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRL 425
Cdd:PRK11006 342 RWQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQtgGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVL 421
|
....*..
gi 492150692 426 PLGLMLP 432
Cdd:PRK11006 422 PERLIAK 428
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-426 |
8.51e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 67.03 E-value: 8.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHA--GNGIEVAAYVSGDrnapYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGLAIVK 399
Cdd:cd16923 1 LQRVFSNLLSNAIKYSpeNTRIYITSFLTDD----VVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTEGAGLGLSIAK 76
|
90 100
....*....|....*....|....*..
gi 492150692 400 RIAAMHGGNVELRNRSGGGLeARVRLP 426
Cdd:cd16923 77 AIIELHGGSASAEYDDNHDL-FKVRLP 102
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
199-427 |
2.51e-13 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 72.25 E-value: 2.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 199 SEMTEVYRAFNQMAEDVEQAGQERELMLAGVSHDLRTPLTRLRLSLELMNDNEFSEGMVRDIEDMDAILDQFLAFIRDGR 278
Cdd:PRK11466 421 AELQELVIEHRQARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDIL 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 279 DEEIEEVDLGDLV--RDVVAPFNNAEGSIRLCLEPIPPFPLRRVS----------------MKRLLTNLIGNARHHAGNG 340
Cdd:PRK11466 501 DYSAIEAGGKNVSvsDEPFEPRPLLESTLQLMSGRVKGRPIRLATdiaddlptalmgdprrIRQVITNLLSNALRFTDEG 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 341 IEVaayVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDrARSGkGTGLGLAIVKRIAAMHGGNVELRNRSGGGLE 420
Cdd:PRK11466 581 SIV---LRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVS-GKRG-GTGLGLTISSRLAQAMGGELSATSTPEVGSC 655
|
....*..
gi 492150692 421 ARVRLPL 427
Cdd:PRK11466 656 FCLRLPL 662
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-426 |
1.02e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 64.41 E-value: 1.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNA-RH-HAGNGIEVAAyvsgdRNAPYVV-LSVLDRGAGIDPSELDTIFNPFIRGD--RARSGKGTGLGLA 396
Cdd:cd16946 5 LQQLFVNLLENSlRYtDTGGKLRIRA-----AQTPQEVrLDVEDSAPGVSDDQLARLFERFYRVEssRNRASGGSGLGLA 79
|
90 100 110
....*....|....*....|....*....|
gi 492150692 397 IVKRIAAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:cd16946 80 ICHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-425 |
2.42e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 62.86 E-value: 2.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 322 MKRLLTNLIGNARHHAGNGIEVAAYVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRArsGKGTGLGLAIVKRI 401
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPV--GKGTGLGLSISYGI 78
|
90 100
....*....|....*....|....
gi 492150692 402 AAMHGGNVELRNRSGGGLEARVRL 425
Cdd:cd16976 79 VEEHGGRLSVANEEGAGARFTFDL 102
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
192-407 |
3.58e-12 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 67.67 E-value: 3.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 192 LPVSDTPSEMTEVYRAFNQMAEDVEQAGQEREL----------MLAGVSHDLRTPLTRLRLSLELMNDNEFSEGMVRDIE 261
Cdd:PRK09303 111 ENLQPSEIDSGRYSQELLQLSDELFVLRQENETlleqlkfkdrVLAMLAHDLRTPLTAASLALETLELGQIDEDTELKPA 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 262 DMDAILDQ-------FLAFIRD------GRDEEIE----EVDLGDLVRDVVAPFNNAEGSIRLCLEP-IPP-FPL----- 317
Cdd:PRK09303 191 LIEQLQDQarrqleeIERLITDllevgrTRWEALRfnpqKLDLGSLCQEVILELEKRWLAKSLEIQTdIPSdLPSvyadq 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 318 RRvsMKRLLTNLIGNARHHAGNG--IEVAAYvsgDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGL 395
Cdd:PRK09303 271 ER--IRQVLLNLLDNAIKYTPEGgtITLSML---HRTTQKVQVSICDTGPGIPEEEQERIFEDRVRLPRDEGTEGYGIGL 345
|
250
....*....|..
gi 492150692 396 AIVKRIAAMHGG 407
Cdd:PRK09303 346 SVCRRIVRVHYG 357
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
266-428 |
5.06e-12 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 67.78 E-value: 5.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 266 ILDQFLAFIRDgRDEEIEEVDLGDLVRDVVApfnnaegSIRLCLEPIPPFPLR-----------RVSMKRLLTNLIGNAR 334
Cdd:PRK13837 502 IIDQILAFGRK-GERNTKPFDLSELVTEIAP-------LLRVSLPPGVELDFDqdqepavvegnPAELQQVLMNLCSNAA 573
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 335 HHA-GNG-IEVAAYVSGDR--------NAP---YVVLSVLDRGAGIDPSELDTIFNPFIrgdRARSGkGTGLGLAIVKRI 401
Cdd:PRK13837 574 QAMdGAGrVDISLSRAKLRapkvlshgVLPpgrYVLLRVSDTGAGIDEAVLPHIFEPFF---TTRAG-GTGLGLATVHGI 649
|
170 180
....*....|....*....|....*..
gi 492150692 402 AAMHGGNVELRNRSGGGLEARVRLPLG 428
Cdd:PRK13837 650 VSAHAGYIDVQSTVGRGTRFDVYLPPS 676
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
324-426 |
7.24e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 61.82 E-value: 7.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 324 RLLTNLIGNARHHA--GNG-IEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDTIFNPFI--RGDRARSGKGTGLGLAIV 398
Cdd:cd16953 3 QVLRNLIGNAISFSppDTGrITVSAMPTGKM----VTISVEDEGPGIPQEKLESIFDRFYteRPANEAFGQHSGLGLSIS 78
|
90 100 110
....*....|....*....|....*....|..
gi 492150692 399 KRIAAMHGGNV--ELRNRSGGGLEAR--VRLP 426
Cdd:cd16953 79 RQIIEAHGGISvaENHNQPGQVIGARftVQLP 110
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-426 |
9.24e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 61.26 E-value: 9.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 339 NGIEVAAYVSGDR------NAP----YVVLSVLDRGAGIDPSELDTIFNPFIrgdrARSGKGTGLGLAIVKRIAAMHGGN 408
Cdd:cd16920 11 NGIEAMSEGGCERreltirTSPaddrAVTISVKDTGPGIAEEVAGQLFDPFY----TTKSEGLGMGLSICRSIIEAHGGR 86
|
90
....*....|....*...
gi 492150692 409 VELRNRSGGGLEARVRLP 426
Cdd:cd16920 87 LSVESPAGGGATFQFTLP 104
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
226-430 |
2.37e-11 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 65.91 E-value: 2.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 226 LAGVSHDLRTPLTRLRLSLELMNDNEFS-EGMVRDIEDMDAILDQFLAFIRDGRD-EEIEE---------VDLGDLVRDV 294
Cdd:PRK09959 716 LATMSHEIRTPISSIMGFLELLSGSGLSkEQRVEAISLAYATGQSLLGLIGEILDvDKIESgnyqlqpqwVDIPTLVQNT 795
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 295 VAPFNNAEGSIRLCLEPIPPFP---LRRV---SMKRLLTNLIGNARHHAGNGIE--VAAYVSGDRNAPYVVLSVLDRGAG 366
Cdd:PRK09959 796 CHSFGAIAASKSIALSCSSTFPdhyLVKIdpqAFKQVLSNLLSNALKFTTEGAVkiTTSLGHIDDNHAVIKMTIMDSGSG 875
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492150692 367 IDPSELDTIFNPFIRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLGLM 430
Cdd:PRK09959 876 LSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPVEIS 939
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
324-424 |
6.23e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 59.01 E-value: 6.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 324 RLLTNLIGNARHHAGNGIEVAAYVSGDRNapYVVLSVLDRGAGIDPSELDTIFNPFIRGDRAR-SGKGTGLGLAIVKRIA 402
Cdd:cd16975 7 RALINIISNACQYAPEGGTVSISIYDEEE--YLYFEIWDNGHGFSEQDLKKALELFYRDDTSRrSGGHYGMGLYIAKNLV 84
|
90 100
....*....|....*....|..
gi 492150692 403 AMHGGNVELRNRSGGGLEARVR 424
Cdd:cd16975 85 EKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
304-425 |
9.70e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 59.18 E-value: 9.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 304 SIRLCLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNGIEVAAYVsgdrNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGD 383
Cdd:cd16954 20 SISLDISPELRFPGERNDLMELLGNLLDNACKWCLEFVEVTARQ----TDGGLHLIVDDDGPGVPESQRSKIFQRGQRLD 95
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 492150692 384 RARSGKgtGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRL 425
Cdd:cd16954 96 EQRPGQ--GLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
321-414 |
1.25e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 58.68 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 321 SMKRLLTNLIGNARHHAGNGIEVAAYVSGDRNapYVVLSVLDRGAGIDPSELDTIFNPFIRGD--RARSGKGTGLGLAIV 398
Cdd:cd16947 20 ALQRILKNLISNAIKYGSDGKFLGMTLREDEK--HVYIDIWDKGKGISETEKDHVFERLYTLEdsRNSAKQGNGLGLTIT 97
|
90
....*....|....*.
gi 492150692 399 KRIAAMHGGNVELRNR 414
Cdd:cd16947 98 KRLAESMGGSIYVNSK 113
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-426 |
3.62e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 56.91 E-value: 3.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 328 NLIGNA-----RHHAGNG-IEVAAYVSGDrnapYVVLSVLDRGAGIDPSELDTIFNpfiRGDRARSGKGTGLGLAIVKRI 401
Cdd:cd16915 7 NLIDNAldalaATGAPNKqVEVFLRDEGD----DLVIEVRDTGPGIAPELRDKVFE---RGVSTKGQGERGIGLALVRQS 79
|
90 100
....*....|....*....|....*
gi 492150692 402 AAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:cd16915 80 VERLGGSITVESEPGGGTTFSIRIP 104
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
237-428 |
4.76e-10 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 59.63 E-value: 4.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 237 LTRLRLSLELMN-----DNEFSEGMVRDIEDM-DAILDQFLAFIRDGRDEEIEEVDLGDLVRDVVAPFNNAEG---SIRL 307
Cdd:COG4585 69 LSAIKLQLEAARrlldaDPEAAREELEEIRELaREALAELRRLVRGLRPPALDDLGLAAALEELAERLLRAAGirvELDV 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 308 CLEPIPPFPLRRVSMKRLLTNLIGNARHHAG-NGIEVAAYVSGDRnapyVVLSVLDRGAGIDPSELdtifnpfirgdrar 386
Cdd:COG4585 149 DGDPDRLPPEVELALYRIVQEALTNALKHAGaTRVTVTLEVDDGE----LTLTVRDDGVGFDPEAA-------------- 210
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 492150692 387 sgKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLG 428
Cdd:COG4585 211 --PGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLPLA 250
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
358-426 |
7.19e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 56.25 E-value: 7.19e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492150692 358 LSVLDRGAGIDPSELDTIFNPFIRGdraRSGkGTGLGLAIVKRIAAMHGGNVELRNRSgGGLEARVRLP 426
Cdd:cd16918 46 VSVIDNGPGIPPDLQDTIFYPMVSG---REN-GTGLGLAIAQNIVSQHGGVIECDSQP-GHTVFSVSLP 109
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
201-418 |
7.36e-10 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 61.11 E-value: 7.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 201 MTEVYRAfnqmAEDVEQAGQERELMLAGVSHDLRTPL------TRLRLSLELmNDNEFSE------------GMVRDIED 262
Cdd:PRK11091 266 ITERKRY----QDALEKASRDKTTFISTISHELRTPLngivglSRILLDTEL-TAEQRKYlktihvsaitlgNIFNDIID 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 263 MDAIldqflafirDGRDEEI--EEVDLGDLVRDVVapfnNAEG------SIRLCLEPIPPFP---------LRRVsmkrl 325
Cdd:PRK11091 341 MDKM---------ERRKLQLdnQPIDFTDFLADLE----NLSGlqaeqkGLRFDLEPLLPLPhkvitdgtrLRQI----- 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 326 LTNLIGNARHHAGNGiEVAAYVSGDRNApYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGK---GTGLGLAIVKRIA 402
Cdd:PRK11091 403 LWNLISNAVKFTQQG-GVTVRVRYEEGD-MLTFEVEDSGIGIPEDELDKIFAMYYQVKDSHGGKpatGTGIGLAVSKRLA 480
|
250
....*....|....*.
gi 492150692 403 AMHGGNVELRNRSGGG 418
Cdd:PRK11091 481 QAMGGDITVTSEEGKG 496
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
326-426 |
7.82e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 56.23 E-value: 7.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 326 LTNLIGNARHHAGNG-------------IEVAAYVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRArsGKGTG 392
Cdd:cd16919 5 ILNLAVNARDAMPEGgrltietsnqrvdADYALNYRDLIPGNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEV--GKGTG 82
|
90 100 110
....*....|....*....|....*....|....
gi 492150692 393 LGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:cd16919 83 LGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
220-275 |
8.29e-10 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 54.53 E-value: 8.29e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492150692 220 QERELMLAGVSHDLRTPLTRLRLSLELMNDN--------EFSEGMVRDIEDMDAILDQFLAFIR 275
Cdd:cd00082 2 QAKGEFLANVSHELRTPLTAIRGALELLEEEllddeeqrEYLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
221-275 |
4.37e-09 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 52.57 E-value: 4.37e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492150692 221 ERELMLAGVSHDLRTPLTRLRLSLELMNDNEFSEG-------MVRDIEDMDAILDQFLAFIR 275
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEqreyletILREAERLLRLINDLLDLSR 62
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
326-418 |
1.23e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 52.59 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 326 LTNLIGNARHHAGNGIEVAAYVSGDRNAPYvvLSVLDRGAGIDPSELDTIFNPFIRGD--RARSGKGTGLGLAIVKRIAA 403
Cdd:cd16952 5 FSNLVSNAVKYTPPSDTITVRWSQEESGAR--LSVEDTGPGIPPEHIPRLTERFYRVDieRCRNTGGTGLGLAIVKHVMS 82
|
90
....*....|....*
gi 492150692 404 MHGGNVELRNRSGGG 418
Cdd:cd16952 83 RHDARLLIASELGKG 97
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
221-275 |
1.41e-08 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 51.06 E-value: 1.41e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492150692 221 ERELMLAGVSHDLRTPLTRLRLSLELMNDN-------EFSEGMVRDIEDMDAILDQFLAFIR 275
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEkldeeqrEYLETILRSAERLLRLINDLLDLSR 62
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
269-426 |
3.11e-08 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 55.83 E-value: 3.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 269 QFLAFIR----DGRdeeieEVDLGDLVRDVVAPFNNAEG---SIRLCLEP-IPPFPLRRVSMKRLLTNLIGNARH---HA 337
Cdd:PRK13557 222 QLLAFARkqrlEGR-----VLNLNGLVSGMGELAERTLGdavTIETDLAPdLWNCRIDPTQAEVALLNVLINARDampEG 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 338 GN------GIEVA----AYVSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIrgDRARSGKGTGLGLAIVKRIAAMHGG 407
Cdd:PRK13557 297 GRvtirtrNVEIEdedlAMYHGLPPGRYVSIAVTDTGSGMPPEILARVMDPFF--TTKEEGKGTGLGLSMVYGFAKQSGG 374
|
170
....*....|....*....
gi 492150692 408 NVELRNRSGGGLEARVRLP 426
Cdd:PRK13557 375 AVRIYSEVGEGTTVRLYFP 393
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-426 |
1.23e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 49.59 E-value: 1.23e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492150692 350 DRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRAR-SGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:cd16948 32 ETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRnFQESTGMGLYLVKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
278-427 |
4.43e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 51.83 E-value: 4.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 278 RDEEIEEVDLGDLVRDVVAPFNNA--EGSIRLCLEpIPPFPLRR-----VSMkrLLTNLIGNARHHAGNG-----IEVAA 345
Cdd:COG3920 352 QSEDWEGVDLRDYLRELLEPLRDSygGRGIRIELD-GPDVELPAdaavpLGL--ILNELVTNALKHAFLSgeggrIRVSW 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 346 YVSGDRnapyVVLSVLDRGAGIDPSeldtifnpfirgdrARSGKGTGLGLAIVKRIAAMHGGNVELRNrsGGGLEARVRL 425
Cdd:COG3920 429 RREDGR----LRLTVSDNGVGLPED--------------VDPPARKGLGLRLIRALVRQLGGTLELDR--PEGTRVRITF 488
|
..
gi 492150692 426 PL 427
Cdd:COG3920 489 PL 490
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
9-310 |
6.47e-07 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 51.65 E-value: 6.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 9 QSFFSRTLWLVLIVVLFSKALTLVYLLMNEDVLVDRQYSHGVALTLRAYWAADENDREAIAEAAGLIRVVGGGVPEGEQH 88
Cdd:COG2770 75 LLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLL 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 89 WPYSEIYQRQMQAELGADTEVRLRVHAPPALWVRAPSLGDGWLKVPLYPHPLRGQKIWSVLGWFLAIGLLSTASAWIFVR 168
Cdd:COG2770 155 AALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLAR 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 169 QLNQPLKRLVFAARQLGQGR-SVRLPVsDTPSEMTEVYRAFNQMAEDVEQAGQERELMLAGVSHDLRTPLTRLRLSLELM 247
Cdd:COG2770 235 RITRPLRRLAEAARRIAAGDlDVRIPV-SRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLAL 313
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492150692 248 NDNEFSEGMVRDIEDMDAILDQFLAFIRDGRDEEIEEVDLGDLVRDVVAPFNNAEGSIRLCLE 310
Cdd:COG2770 314 LLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVL 376
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
316-429 |
1.26e-06 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 51.00 E-value: 1.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 316 PLRrvsMKRLLTNLIGNARHHAGNG-----IEVAAyVSGDRnapyVVL--SVLDRGAGIDPSELDTIFNPFIRGDRA--- 385
Cdd:PRK11107 406 PLR---LQQIITNLVGNAIKFTESGnidilVELRA-LSNTK----VQLevQIRDTGIGISERQQSQLFQAFRQADASisr 477
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 492150692 386 RSGkGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLPLGL 429
Cdd:PRK11107 478 RHG-GTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLPLDL 520
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
172-213 |
1.41e-06 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 44.74 E-value: 1.41e-06
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 492150692 172 QPLKRLVFAARQLGQGR-SVRLPVSdTPSEMTEVYRAFNQMAE 213
Cdd:cd06225 2 RPLRRLTEAARRIAEGDlDVRVPVR-SKDEIGELARAFNQMAE 43
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
168-218 |
2.25e-06 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 44.55 E-value: 2.25e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 492150692 168 RQLNQPLKRLVFAARQLGQGR-SVRLPVsDTPSEMTEVYRAFNQMAEDVEQA 218
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDlTVRLPV-DGRDEIGELARAFNEMADRLEET 51
|
|
| HAMP |
pfam00672 |
HAMP domain; |
165-217 |
3.89e-06 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 43.77 E-value: 3.89e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 492150692 165 IFVRQLNQPLKRLVFAARQLGQGR-SVRLPVSdTPSEMTEVYRAFNQMAEDVEQ 217
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDlDVRLPVS-GRDEIGELARAFNQMAERLRE 53
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
332-426 |
2.84e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 42.54 E-value: 2.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 332 NARHHAGNGievAAYVSGDRNAPYVVLSVLDRGAGIDPseldtifnpfirgdrARSGKGTGLGLAIVKRIAAMHGGNVEL 411
Cdd:cd16917 11 NALKHAGAS---RVRVTLSYTADELTLTVVDDGVGFDG---------------PAPPGGGGFGLLGMRERAELLGGTLTI 72
|
90
....*....|....*
gi 492150692 412 RNRSGGGLEARVRLP 426
Cdd:cd16917 73 GSRPGGGTRVTARLP 87
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
28-428 |
3.20e-05 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 46.03 E-value: 3.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 28 ALTLVYLLMNEDVLVDRQYSHGVALTLRAYWAADENDREAIAEAAGLIRVVGGGVPEGEQHWPYSEIYQRQMQAELGADT 107
Cdd:COG3850 1 LRELLLLALALLRLLLALLALLLLALLLLSLLALLLLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 108 EVRLRVHAPPALWVRAPSLGDGWLKVPLYPHPLRGQKIWSVLGWFLAIgLLSTASAWIFVRQLNQPLKRLVFAARQLGQG 187
Cdd:COG3850 81 LLLLLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLAL-LLALLLAYLLRRRIVRPLRRLTQAAERIARG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 188 R-SVRLPVSdTPSEMTEVYRAFNQMAEDVEQAGQERELMLAGVSHDLRTPLTRLRLSLELMNDNEFSEGMVRDIEDMDAI 266
Cdd:COG3850 160 DfDARVPVS-GRDELGTLARAFNRMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAAL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 267 LDQFLAFIRDGRDEEIEEVDLGDLVRDVVAPFNNAEGSIRLCLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNGIEVAAY 346
Cdd:COG3850 239 LLLLLLQDALAESELLALNILAGLLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 347 VSGDRNAPYVVLSVLDRGAGIDPSELDTIFNPFIRGDRARSGKGTGLGLAIVKRIAAMHGGNVELRNRSGGGLEARVRLP 426
Cdd:COG3850 319 LLQAIANASLLLIALASVVAALLELASILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAG 398
|
..
gi 492150692 427 LG 428
Cdd:COG3850 399 QG 400
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
325-417 |
1.50e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 41.44 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 325 LLTNLIGNARHHAGNG-IEVAAYVSGDRnapyVVLSVLDRGAGIDPSELDtifnpfirgDRARSGKGTGLGLAIVKRIAA 403
Cdd:COG2172 42 AVTNAVRHAYGGDPDGpVEVELELDPDG----LEIEVRDEGPGFDPEDLP---------DPYSTLAEGGRGLFLIRRLMD 108
|
90
....*....|....
gi 492150692 404 mhggNVELRNRSGG 417
Cdd:COG2172 109 ----EVEYESDPGG 118
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
146-215 |
4.05e-04 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 42.53 E-value: 4.05e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492150692 146 WSVLGWFLAIGLLSTASAWIFV-----RQLNQPLKRLVFAARQLGQGR--SVRLPVSDtPSEMTEVYRAFNQMAEDV 215
Cdd:PRK10935 147 LILLAAISLLGLILILTLVFFTvrftrRQVVAPLNQLVTASQQIEKGQfdHIPLDTTL-PNELGLLAKAFNQMSSEL 222
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
360-427 |
5.20e-04 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 41.99 E-value: 5.20e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492150692 360 VLDRGAGIDPSELDTIFNPFIRGdraRSGkGTGLGLAIVKRIAAMHGGNVELrNRSGGGLEARVRLPL 427
Cdd:PRK11073 285 IEDNGPGIPPHLQDTLFYPMVSG---REG-GTGLGLSIARNLIDQHSGKIEF-TSWPGHTEFSVYLPI 347
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
140-213 |
1.02e-03 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 41.54 E-value: 1.02e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492150692 140 LRGQKIWSVLGWFLAIGLLSTASAWIFVRQLNQPLKRLVFAARQLGQGR-SVRLPVsDTPSEMTEVYRAFNQMAE 213
Cdd:COG0840 176 AAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDlTVRIDV-DSKDEIGQLADAFNRMIE 249
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
143-423 |
1.30e-03 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 40.77 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 143 QKIWSVLGWF---------LAIGLLSTASAWIFvrqlnQPLKRLVFAARQLGQGRSVRLPvSDTPSEMTEVYRAFNQMAE 213
Cdd:PRK10815 184 QRSYMVWSWFsyvllanllLVIPLLWLAAWWSL-----RPIEALAKQVRELEEGEREQLD-PNPPRELTSLVRNLNRLLK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 214 DVEQAGQERELMLAGVSHDLRTPLTRLRLSLELMNDnefseGMVRDIEDMDAI-LDQ----------FL--AFIRDGRDE 280
Cdd:PRK10815 258 NERERYTKYRTTLTDLTHSLKTPLAVLQSTLRSLRS-----GKQMSVEQAEPImLEQisrisqqigyYLhrASMRSEHNL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492150692 281 EIEEVD-----LGDLVRDVVAPFNNAEGSIRLCLEPIPPFPLRRVSMKRLLTNLIGNARHHAGNGIEVAAYVSGDrnapY 355
Cdd:PRK10815 333 LSRELHsvaplLDNLTSALNKVYQRKGVNITLDISPEITFVGEKNDFMEVMGNVLDNACKYCLEFVEISARQTDE----H 408
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492150692 356 VVLSVLDRGAGIDPSELDTIFnpfIRGDRA---RSGKGTglGLAIVKRIAAMHGGNVELRNRSGGGleARV 423
Cdd:PRK10815 409 LHIVVEDDGPGIPESKRELIF---DRGQRAdtlRPGQGL--GLSVAREITEQYEGKISAGDSPLGG--ARM 472
|
|
| |
