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Conserved domains on  [gi|492967867|ref|WP_006072188|]
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MULTISPECIES: Sec-independent protein translocase subunit TatA [Vibrio]

Protein Classification

Sec-independent protein translocase subunit TatA( domain architecture ID 10012220)

Sec-independent protein translocase subunit TatA may form the protein-conducting channel of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-84 7.50e-41

twin-arginine translocase subunit TatA;


:

Pssm-ID: 179867  Cd Length: 81  Bit Score: 128.82  E-value: 7.50e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDntTAKSDTKDADFEPKNIEQKQTaDASTEAKKD 80
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEE--SAKANKKDADFEPKNLEQAKT-EAAAEKKKD 77


                ....
gi 492967867 81 KEQA 84
Cdd:PRK04598 78 KEQA 81
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-84 7.50e-41

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 128.82  E-value: 7.50e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDntTAKSDTKDADFEPKNIEQKQTaDASTEAKKD 80
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEE--SAKANKKDADFEPKNLEQAKT-EAAAEKKKD 77


                ....
gi 492967867 81 KEQA 84
Cdd:PRK04598 78 KEQA 81
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-68 1.27e-16

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 67.27  E-value: 1.27e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDN----TTAKSDTKDADFEPKNIEQK 68
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEeldeELKEEELRKSEKEAEELKKA 72
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-48 2.57e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 65.71  E-value: 2.57e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 492967867   3 GISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDN 48
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-54 9.16e-10

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 49.23  E-value: 9.16e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 492967867   4 ISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAKSD 54
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEA 51
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-84 7.50e-41

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 128.82  E-value: 7.50e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDntTAKSDTKDADFEPKNIEQKQTaDASTEAKKD 80
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEE--SAKANKKDADFEPKNLEQAKT-EAAAEKKKD 77


                ....
gi 492967867 81 KEQA 84
Cdd:PRK04598 78 KEQA 81
tatA PRK03554
Sec-independent protein translocase subunit TatA;
1-80 1.41e-24

Sec-independent protein translocase subunit TatA;


Pssm-ID: 179592  Cd Length: 89  Bit Score: 87.81  E-value: 1.41e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAKSdTKDADFEPKNIEQKQTADASTEAKKD 80
Cdd:PRK03554  1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKT-SQDADFTAKTIADKQADTNQEQAKTE 79
tatA PRK02958
Sec-independent protein translocase subunit TatA;
1-71 1.46e-22

Sec-independent protein translocase subunit TatA;


Pssm-ID: 235091  Cd Length: 73  Bit Score: 82.32  E-value: 1.46e-22
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAKSDTKDADFEPKNIEQKQTA 71
Cdd:PRK02958  1 MGSFSIWHWLIVLVIVVLVFGTKKLRNIGSDLGGAVKGFKDGMKEGETPQEAQAQQLPDSGTIDVEAKEKS 71
tatA PRK01833
Sec-independent protein translocase subunit TatA;
1-84 3.71e-22

Sec-independent protein translocase subunit TatA;


Pssm-ID: 167284  Cd Length: 74  Bit Score: 81.08  E-value: 3.71e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDdnttaksDTKDADFepKNIEQKQTAdASTEAKKD 80
Cdd:PRK01833  1 MGGISIWQLLIIVAIIVLLFGTKKLRTLGTDLGESVKGFKKAMADD-------KPKDAEF--EKVEAKEAA-STEQKAKE 70


                ....
gi 492967867 81 KEQA 84
Cdd:PRK01833 71 KEQA 74
tatE PRK03625
twin-arginine translocase subunit TatE;
1-61 2.16e-19

twin-arginine translocase subunit TatE;


Pssm-ID: 179612  Cd Length: 67  Bit Score: 74.03  E-value: 2.16e-19
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAKSDTKDADFE 61
Cdd:PRK03625  1 MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDDDAAAKKGADVDLQAE 61
tatE PRK01614
Sec-independent protein translocase subunit TatA;
1-83 3.57e-17

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234965  Cd Length: 85  Bit Score: 69.15  E-value: 3.57e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAKSDTKDADFEPKNIEQKQTADASTEAKKD 80
Cdd:PRK01614  1 MEGLSITKLLVVGILIVLLFGTSKLRTLGADLGAALKGFKKAMRNDDEVSTSVLGETKMSAETKTVAETKAASDSQAAAS 80


                ...
gi 492967867 81 KEQ 83
Cdd:PRK01614 81 VER 83
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-68 1.27e-16

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 67.27  E-value: 1.27e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDN----TTAKSDTKDADFEPKNIEQK 68
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEeldeELKEEELRKSEKEAEELKKA 72
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-48 2.57e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 65.71  E-value: 2.57e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 492967867   3 GISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDN 48
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
tatA PRK04561
twin arginine translocase protein A; Provisional
 1-52 1.09e-13

twin arginine translocase protein A; Provisional


Pssm-ID: 179864  Cd Length: 75  Bit Score: 59.93  E-value: 1.09e-13
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAK 52
Cdd:PRK04561  1 MGSFSIWHWLVVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDDKPAGQ 52
tatA PRK00442
twin-arginine translocase TatA/TatE family subunit;
3-47 1.15e-13

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234764  Cd Length: 92  Bit Score: 60.28  E-value: 1.15e-13
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 492967867  3 GISIWQ-LLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDD 47
Cdd:PRK00442  2 GIFDWKhWIVILVVVVLVFGTKKLKNLGSDVGESIKGFRKAMNEDE 47
tatA PRK00720
twin-arginine translocase TatA/TatE family subunit;
1-79 1.59e-12

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234822  Cd Length: 78  Bit Score: 56.97  E-value: 1.59e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAksdtkDADFEPKNIEQKQTADASTEAKK 79
Cdd:PRK00720  1 MGSFSIWHWLIVLAVVLLLFGRGKISELMGDVAKGIKSFKKGMADDDAPPA-----EPPEPVRTIDHKADEPVAPVKKD 74
tatA PRK00575
Sec-independent protein translocase subunit TatA;
1-51 7.47e-11

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 53.21  E-value: 7.47e-11
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFK---KAMSEDDNTTA 51
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKsevKEMQSDNKAEA 54
tatA PRK14859
twin arginine translocase protein A; Provisional
 1-63 1.09e-10

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 52.03  E-value: 1.09e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAKSDTKDADFEPK 63
Cdd:PRK14859  1 MFGIGMPELIVILVIVLIVFGAGKLPEIGGGLGKSIKNFKKATSEKEEIEIKPTKKEDKKKKK 63
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
3-83 1.88e-10

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 52.03  E-value: 1.88e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  3 GISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAK--SDTKDADFEPKNIEQKQTADASTEaKKD 80
Cdd:PRK14857  5 GIGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQEASKEFENEIKRemAEPEQEVKAPAELESNQTNEANQE-QVD 83


                ...
gi 492967867 81 KEQ 83
Cdd:PRK14857 84 AEN 86
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-54 9.16e-10

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 49.23  E-value: 9.16e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 492967867   4 ISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAKSD 54
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEA 51
tatA PRK14860
twin arginine translocase protein A; Provisional
 1-62 1.29e-09

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 48.96  E-value: 1.29e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTT--AKSDTKDADFEP 62
Cdd:PRK14860  1 MFGFGMPELIVILVIALVVFGPAKLPQLGQALGGAIRNFKKASNEEDVVTinNEKGKEDQARSD 64
tatA PRK00191
twin arginine translocase protein A; Provisional
 7-72 4.39e-09

twin arginine translocase protein A; Provisional


Pssm-ID: 234683 [Multi-domain]  Cd Length: 84  Bit Score: 48.41  E-value: 4.39e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  7 WQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFK---KAMSEDDNTTAKSDTKDADF-EPKNIEQKQTAD 72
Cdd:PRK00191  6 WEIGIIVLLIIVLFGAKKLPDAARSIGRSMRIFKsevKEMSKDDQTPEQQQQQPQQQiAPNQIEAPQPNF 75
tatA PRK01470
twin arginine translocase protein A; Provisional
 3-52 3.73e-07

twin arginine translocase protein A; Provisional


Pssm-ID: 179298  Cd Length: 51  Bit Score: 42.53  E-value: 3.73e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 492967867  3 GISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSEDDNTTAK 52
Cdd:PRK01470  2 GMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGSDNDK 51
tatA PRK14861
twin arginine translocase protein A; Provisional
 1-56 1.62e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 41.11  E-value: 1.62e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKA----MSEDDNTTAKSDTK 56
Cdd:PRK14861  2 FSNIGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKAtkelTDDDFQEKKKKEKM 61
tatA PRK14858
twin arginine translocase protein A; Provisional
 1-84 2.69e-05

twin arginine translocase protein A; Provisional


Pssm-ID: 184860  Cd Length: 108  Bit Score: 39.08  E-value: 2.69e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492967867   1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGGDLGGAVKGFKKAMSE-DDNTTAKSDTKDADFEPKNIEQKQTADASTEAKK 79
Cdd:PRK14858   1 MFGIGMPELIVILVIALIVIGPQKLPDLARSLGRGLAEFKKATDDfKQSMQEESRTAEEKEKAEKLAETKKEAEAPEAKA 80


                 ....*
gi 492967867  80 DKEQA 84
Cdd:PRK14858  81 EEDQA 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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