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Conserved domains on  [gi|496535546|ref|WP_009242237|]
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MULTISPECIES: immunoglobulin-like domain-containing protein [Bacillati]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
164-344 2.20e-16

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 81.90  E-value: 2.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 164 ISSLEGIQYLTNLQSLDVSTTSVSDLSPV--KNSSLKRLDCRSSKVGSV--DLTRYPNLEAFVCDNTSINSLD--VSKNE 237
Cdd:COG4886  103 LSGNEELSNLTNLESLDLSGNQLTDLPEElaNLTNLKELDLSNNQLTDLpePLGNLTNLKSLDLSNNQLTDLPeeLGNLT 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 238 KLNTLFADSTSISNL--DVTNNPNLEQLSCSNTGLMEL--DVTHNPQLVTLDIGDTKVKTL-DISKNPNLKQLSCYMTNI 312
Cdd:COG4886  183 NLKELDLSNNQITDLpePLGNLTNLEELDLSGNQLTDLpePLANLTNLETLDLSNNQLTDLpELGNLTNLEELDLSNNQL 262

                        170       180       190
                 ....*....|....*....|....*....|...
gi 496535546 313 AELDVTKN-TKLTRLFCHDTTIKKLDLSNNLEL 344
Cdd:COG4886  263 TDLPPLANlTNLKTLDLSNNQLTDLKLKELELL 295
DUF5011 super family cl47259
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 481-550 3.39e-12

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


The actual alignment was detected with superfamily member pfam16403:

Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 62.18  E-value: 3.39e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  481 ANDVTLNVGDTFDPlANVTATDKEDGtitLTKDNIVANDVDTSKAGTYHVTYKVTDKNGASAKKTITVTV 550
Cdd:pfam16403   6 DNDITIELGTTYED-PGATATDNDGD---LTDKVKVTGSVDTSKPGTYTLTYTVTDSDGNSATVTRTVTV 71
DUF5011 super family cl47259
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 565-634 6.37e-10

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


The actual alignment was detected with superfamily member pfam16403:

Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 55.63  E-value: 6.37e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496535546  565 ANDVTLNVGDTF-DPlvNATATDKEDGtiiLTKDNIIANDVDTSKAGTYHVTFRVVDKNGAITEKTITVTV 634
Cdd:pfam16403   6 DNDITIELGTTYeDP--GATATDNDGD---LTDKVKVTGSVDTSKPGTYTLTYTVTDSDGNSATVTRTVTV 71
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
164-344 2.20e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 81.90  E-value: 2.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 164 ISSLEGIQYLTNLQSLDVSTTSVSDLSPV--KNSSLKRLDCRSSKVGSV--DLTRYPNLEAFVCDNTSINSLD--VSKNE 237
Cdd:COG4886  103 LSGNEELSNLTNLESLDLSGNQLTDLPEElaNLTNLKELDLSNNQLTDLpePLGNLTNLKSLDLSNNQLTDLPeeLGNLT 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 238 KLNTLFADSTSISNL--DVTNNPNLEQLSCSNTGLMEL--DVTHNPQLVTLDIGDTKVKTL-DISKNPNLKQLSCYMTNI 312
Cdd:COG4886  183 NLKELDLSNNQITDLpePLGNLTNLEELDLSGNQLTDLpePLANLTNLETLDLSNNQLTDLpELGNLTNLEELDLSNNQL 262

                        170       180       190
                 ....*....|....*....|....*....|...
gi 496535546 313 AELDVTKN-TKLTRLFCHDTTIKKLDLSNNLEL 344
Cdd:COG4886  263 TDLPPLANlTNLKTLDLSNNQLTDLKLKELELL 295
DUF5011 pfam16403
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 481-550 3.39e-12

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 62.18  E-value: 3.39e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  481 ANDVTLNVGDTFDPlANVTATDKEDGtitLTKDNIVANDVDTSKAGTYHVTYKVTDKNGASAKKTITVTV 550
Cdd:pfam16403   6 DNDITIELGTTYED-PGATATDNDGD---LTDKVKVTGSVDTSKPGTYTLTYTVTDSDGNSATVTRTVTV 71
DUF5011 pfam16403
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 565-634 6.37e-10

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 55.63  E-value: 6.37e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496535546  565 ANDVTLNVGDTF-DPlvNATATDKEDGtiiLTKDNIIANDVDTSKAGTYHVTFRVVDKNGAITEKTITVTV 634
Cdd:pfam16403   6 DNDITIELGTTYeDP--GATATDNDGD---LTDKVKVTGSVDTSKPGTYTLTYTVTDSDGNSATVTRTVTV 71
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 153-341 1.21e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 50.82  E-value: 1.21e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 153 AQFLNLHGMKTISSLEG----IQYLTN---LQSLDVSTTSVSDLSP------VKNSSLKRLDCRSSKVGS--------VD 211
Cdd:cd00116   53 LKELCLSLNETGRIPRGlqslLQGLTKgcgLQELDLSDNALGPDGCgvleslLRSSSLQELKLNNNGLGDrglrllakGL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 212 LTRYPNLEAFVCDNtsiNSLDVSKNEKLNTLFADSTSISNLDVTNNP-----------------NLEQLSCSNTGLMELD 274
Cdd:cd00116  133 KDLPPALEKLVLGR---NRLEGASCEALAKALRANRDLKELNLANNGigdagiralaeglkancNLEVLDLNNNGLTDEG 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 275 -------VTHNPQLVTLDIGDTKVKTLDISK--------NPNLKQLSCYMTNIAELDVTKNTKLTRLFChdtTIKKLDLS 339
Cdd:cd00116  210 asalaetLASLKSLEVLNLGDNNLTDAGAAAlasallspNISLLTLSLSCNDITDDGAKDLAEVLAEKE---SLLELDLR 286


                 ..
gi 496535546 340 NN 341
Cdd:cd00116  287 GN 288
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
65-314 4.23e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 50.08  E-value: 4.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  65 ITDKEQEETAE------NAETLKEESAKQetpaTPEKEVVTEDKTVE----ASKNTEVKAGSIAIDETHFPDKVfREQII 134
Cdd:PRK15370 128 VTESEQASSASgskdavNYELIWSEWVKE----APAKEAANREEAVQrmrdCLKNNKTELRLKILGLTTIPACI-PEQIT 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 135 AeFDKDGDSVLSVDEiskaqflNLHG-MKTISSLEgiQYLTNL--------QSLDVSTTSVSDLSPVKNSSLKRLDCRSS 205
Cdd:PRK15370 203 T-LILDNNELKSLPE-------NLQGnIKTLYANS--NQLTSIpatlpdtiQEMELSINRITELPERLPSALQSLDLFHN 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 206 KVGSVDLTRYPNLEAFVCDNTSINSLDVSKNEKLNTLFADSTSISNLDVTNNPNLEQLSCSNTGLMELDVTHNPQLVTLD 285
Cdd:PRK15370 273 KISCLPENLPEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPGLKTLEAGENALTSLPASLPPELQVLD 352

                        250       260       270
                 ....*....|....*....|....*....|..
gi 496535546 286 IGDTKVKTLDISKNPNLKQLSC---YMTNIAE 314
Cdd:PRK15370 353 VSKNQITVLPETLPPTITTLDVsrnALTNLPE 384
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 474-643 3.09e-05

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 47.73  E-value: 3.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  474 NTAPTISAN-DVTLNVGDTFDPLANVTATDKEDGT----------ITLTKDNI-----VANDVDTSKAGTYHVTykVTDk 537
Cdd:NF038112 1280 NRAPVAVAGaPATVDERSTVTLDGSGTDADGDALTyawtqtsgpaVTLTGATTatatfTAPEVTADTQLTFTLT--VSD- 1356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  538 NGASAKKTITVTVKqntgDLNSAPIISA-NDVTLNVGDTFdpLVNATATDKEDGTIILTKDNIIANDVDTSKAGTYH--- 613
Cdd:NF038112 1357 GTASATDTVTVTVR----NVNRAPVANAgADQTVDERSTV--TLSGSATDPDGDALTYAWTQTAGPTVTLTGADTATasf 1430

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 496535546  614 ----------VTFRVVDKNGAITEKTITVTVKEKATNK-PV 643
Cdd:NF038112 1431 tapevaadteLTFQLTVSADGQASADVTVTVTVRNVNRaPV 1471
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 471-635 1.64e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 41.95  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  471 GEDNTAPTISAndVTLNVGDTFDPLAN-------------VTATDKEDGTITLTkdnivANDVDTSKAGTYHVTykVTDK 537
Cdd:NF038112 1193 GPDQTVLERTT--VTLNGSGSFDPDGDpltyawtqvsgpaVTLTGADTATPSFT-----APEVTADTVLTFQLV--VSDG 1263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  538 NGASAKKTITVTVKQntgdLNSAPIISAN-DVTLNVGDTFDplVNATATDkEDG-------------TIILTKDNI---- 599
Cdd:NF038112 1264 TKTSAPDTVTVLVRN----VNRAPVAVAGaPATVDERSTVT--LDGSGTD-ADGdaltyawtqtsgpAVTLTGATTatat 1336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 496535546  600 -IANDV--DTSkagtyhVTFRVVDKNGAIT-EKTITVTVK 635
Cdd:NF038112 1337 fTAPEVtaDTQ------LTFTLTVSDGTASaTDTVTVTVR 1370
tand_rpt_95 NF012211
tandem-95 repeat; This 95-amino acid repeat occurs in tandem in proteins that may be several ...
 504-634 9.82e-03

tandem-95 repeat; This 95-amino acid repeat occurs in tandem in proteins that may be several thousand amino acids long.


Pssm-ID: 333740 [Multi-domain]  Cd Length: 98  Bit Score: 36.07  E-value: 9.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 504 EDGTITLTKDNIVANDVDTSkagtyhvtykvtdkngasakktitvtvkqntGDLNSAPIISANDVTlnvgdtfdplvNAT 583
Cdd:NF012211   4 EDGSITITQEQLLANASDVD-------------------------------GDDLTVSNVSYSGPT-----------NGT 41

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 496535546 584 ATDKEDGTIILTKDNIIANDVDtskagtyhVTFRVVDKNGAITEKTITVTV 634
Cdd:NF012211  42 VTDNGDGTYTYTPNENFNGDDS--------FTYTVSDGTGATATATVFVTV 84
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
164-344 2.20e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 81.90  E-value: 2.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 164 ISSLEGIQYLTNLQSLDVSTTSVSDLSPV--KNSSLKRLDCRSSKVGSV--DLTRYPNLEAFVCDNTSINSLD--VSKNE 237
Cdd:COG4886  103 LSGNEELSNLTNLESLDLSGNQLTDLPEElaNLTNLKELDLSNNQLTDLpePLGNLTNLKSLDLSNNQLTDLPeeLGNLT 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 238 KLNTLFADSTSISNL--DVTNNPNLEQLSCSNTGLMEL--DVTHNPQLVTLDIGDTKVKTL-DISKNPNLKQLSCYMTNI 312
Cdd:COG4886  183 NLKELDLSNNQITDLpePLGNLTNLEELDLSGNQLTDLpePLANLTNLETLDLSNNQLTDLpELGNLTNLEELDLSNNQL 262

                        170       180       190
                 ....*....|....*....|....*....|...
gi 496535546 313 AELDVTKN-TKLTRLFCHDTTIKKLDLSNNLEL 344
Cdd:COG4886  263 TDLPPLANlTNLKTLDLSNNQLTDLKLKELELL 295
DUF5011 pfam16403
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 481-550 3.39e-12

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 62.18  E-value: 3.39e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  481 ANDVTLNVGDTFDPlANVTATDKEDGtitLTKDNIVANDVDTSKAGTYHVTYKVTDKNGASAKKTITVTV 550
Cdd:pfam16403   6 DNDITIELGTTYED-PGATATDNDGD---LTDKVKVTGSVDTSKPGTYTLTYTVTDSDGNSATVTRTVTV 71
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
154-412 1.30e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 67.27  E-value: 1.30e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 154 QFLNLHGMKtISSL-EGIQYLTNLQSLDVSTTSVSDLSPV--KNSSLKRLDCRSSKVGSV--DLTRYPNLEAFVCDNTSI 228
Cdd:COG4886  139 KELDLSNNQ-LTDLpEPLGNLTNLKSLDLSNNQLTDLPEElgNLTNLKELDLSNNQITDLpePLGNLTNLEELDLSGNQL 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 229 NSL--DVSKNEKLNTLFADSTSISNL-DVTNNPNLEQLSCSNTGLMELDVTHN-PQLVTLDIGDTKVKTLDISKNPNLKQ 304
Cdd:COG4886  218 TDLpePLANLTNLETLDLSNNQLTDLpELGNLTNLEELDLSNNQLTDLPPLANlTNLKTLDLSNNQLTDLKLKELELLLG 297

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 305 LSCYMTNIAELDVTKNTKLTRLFCHDTTIKKLDLSNNLELEMLRCGEIFEQGIRGLDISKNTKIKKLICDDLYWLNVGEN 384
Cdd:COG4886  298 LNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEA 377

                        250       260
                 ....*....|....*....|....*...
gi 496535546 385 KVLENNHAFVGNGYIDIKGNKIDLKKDV 412
Cdd:COG4886  378 TLLTLALLLLTLLLLLLTTTAGVLLLTL 405
DUF5011 pfam16403
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 565-634 6.37e-10

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 55.63  E-value: 6.37e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496535546  565 ANDVTLNVGDTF-DPlvNATATDKEDGtiiLTKDNIIANDVDTSKAGTYHVTFRVVDKNGAITEKTITVTV 634
Cdd:pfam16403   6 DNDITIELGTTYeDP--GATATDNDGD---LTDKVKVTGSVDTSKPGTYTLTYTVTDSDGNSATVTRTVTV 71
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 153-341 1.21e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 50.82  E-value: 1.21e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 153 AQFLNLHGMKTISSLEG----IQYLTN---LQSLDVSTTSVSDLSP------VKNSSLKRLDCRSSKVGS--------VD 211
Cdd:cd00116   53 LKELCLSLNETGRIPRGlqslLQGLTKgcgLQELDLSDNALGPDGCgvleslLRSSSLQELKLNNNGLGDrglrllakGL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 212 LTRYPNLEAFVCDNtsiNSLDVSKNEKLNTLFADSTSISNLDVTNNP-----------------NLEQLSCSNTGLMELD 274
Cdd:cd00116  133 KDLPPALEKLVLGR---NRLEGASCEALAKALRANRDLKELNLANNGigdagiralaeglkancNLEVLDLNNNGLTDEG 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 275 -------VTHNPQLVTLDIGDTKVKTLDISK--------NPNLKQLSCYMTNIAELDVTKNTKLTRLFChdtTIKKLDLS 339
Cdd:cd00116  210 asalaetLASLKSLEVLNLGDNNLTDAGAAAlasallspNISLLTLSLSCNDITDDGAKDLAEVLAEKE---SLLELDLR 286


                 ..
gi 496535546 340 NN 341
Cdd:cd00116  287 GN 288
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
65-314 4.23e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 50.08  E-value: 4.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  65 ITDKEQEETAE------NAETLKEESAKQetpaTPEKEVVTEDKTVE----ASKNTEVKAGSIAIDETHFPDKVfREQII 134
Cdd:PRK15370 128 VTESEQASSASgskdavNYELIWSEWVKE----APAKEAANREEAVQrmrdCLKNNKTELRLKILGLTTIPACI-PEQIT 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 135 AeFDKDGDSVLSVDEiskaqflNLHG-MKTISSLEgiQYLTNL--------QSLDVSTTSVSDLSPVKNSSLKRLDCRSS 205
Cdd:PRK15370 203 T-LILDNNELKSLPE-------NLQGnIKTLYANS--NQLTSIpatlpdtiQEMELSINRITELPERLPSALQSLDLFHN 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 206 KVGSVDLTRYPNLEAFVCDNTSINSLDVSKNEKLNTLFADSTSISNLDVTNNPNLEQLSCSNTGLMELDVTHNPQLVTLD 285
Cdd:PRK15370 273 KISCLPENLPEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPGLKTLEAGENALTSLPASLPPELQVLD 352

                        250       260       270
                 ....*....|....*....|....*....|..
gi 496535546 286 IGDTKVKTLDISKNPNLKQLSC---YMTNIAE 314
Cdd:PRK15370 353 VSKNQITVLPETLPPTITTLDVsrnALTNLPE 384
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 474-643 3.09e-05

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 47.73  E-value: 3.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  474 NTAPTISAN-DVTLNVGDTFDPLANVTATDKEDGT----------ITLTKDNI-----VANDVDTSKAGTYHVTykVTDk 537
Cdd:NF038112 1280 NRAPVAVAGaPATVDERSTVTLDGSGTDADGDALTyawtqtsgpaVTLTGATTatatfTAPEVTADTQLTFTLT--VSD- 1356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  538 NGASAKKTITVTVKqntgDLNSAPIISA-NDVTLNVGDTFdpLVNATATDKEDGTIILTKDNIIANDVDTSKAGTYH--- 613
Cdd:NF038112 1357 GTASATDTVTVTVR----NVNRAPVANAgADQTVDERSTV--TLSGSATDPDGDALTYAWTQTAGPTVTLTGADTATasf 1430

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 496535546  614 ----------VTFRVVDKNGAITEKTITVTVKEKATNK-PV 643
Cdd:NF038112 1431 tapevaadteLTFQLTVSADGQASADVTVTVTVRNVNRaPV 1471
Big_3 pfam07523
Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like ...
 483-550 6.10e-05

Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.


Pssm-ID: 400072 [Multi-domain]  Cd Length: 67  Bit Score: 41.51  E-value: 6.10e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  483 DVTLNVGDTFDPLAN-VTATDKeDGTITLTKDNI-VANDVDTSKAGTYHVTYKVtdkngASAKKTITVTV 550
Cdd:pfam07523   4 KTTYYVGDSWDAEDNfVSATYK-DGDAEVPFDDVeVSGTVDSTKAGEYTVTYTY-----KGVSATFTVTV 67
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 480-551 1.09e-03

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 38.36  E-value: 1.09e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 496535546  480 SANDVTLNVGDTFDPLANVTATDK--EDGTITltkdniVANDVDTSKAGTYHVTYKVTDKNGASAKKTITVTVK 551
Cdd:pfam08428   8 KGKDITVEVGETPDAEDGIKNKDDlpEGTKYT------WKTPPDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 471-635 1.64e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 41.95  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  471 GEDNTAPTISAndVTLNVGDTFDPLAN-------------VTATDKEDGTITLTkdnivANDVDTSKAGTYHVTykVTDK 537
Cdd:NF038112 1193 GPDQTVLERTT--VTLNGSGSFDPDGDpltyawtqvsgpaVTLTGADTATPSFT-----APEVTADTVLTFQLV--VSDG 1263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  538 NGASAKKTITVTVKQntgdLNSAPIISAN-DVTLNVGDTFDplVNATATDkEDG-------------TIILTKDNI---- 599
Cdd:NF038112 1264 TKTSAPDTVTVLVRN----VNRAPVAVAGaPATVDERSTVT--LDGSGTD-ADGdaltyawtqtsgpAVTLTGATTatat 1336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 496535546  600 -IANDV--DTSkagtyhVTFRVVDKNGAIT-EKTITVTVK 635
Cdd:NF038112 1337 fTAPEVtaDTQ------LTFTLTVSDGTASaTDTVTVTVR 1370
PKD_4 pfam18911
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
 474-550 3.54e-03

PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.


Pssm-ID: 436824 [Multi-domain]  Cd Length: 85  Bit Score: 36.86  E-value: 3.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546  474 NTAPTISAN-DVTLNVGDT--FDplanVTATDKEDGTITLTK----DNIVANDVDTS----KAGTYHVTYKVTDKNGAS- 541
Cdd:pfam18911   1 NAAPVADAGgDRIVAEGETvtFD----ASASDDPDGDILSYRwdfgDGTTATGANVShtyaAPGTYTVTLTVTDDSGASn 76


                  ....*....
gi 496535546  542 AKKTITVTV 550
Cdd:pfam18911  77 STATDTVTV 85
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 164-258 3.94e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.38  E-value: 3.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 164 ISSLEGIQYLTNLQSLDVS-------------TTSVSDLSPvknsSLKRLDCRSSKVGSVDltrypNLEAFvcdnTSINS 230
Cdd:cd21340   80 ISVVEGLENLTNLEELHIEnqrlppgekltfdPRSLAALSN----SLRVLNISGNNIDSLE-----PLAPL----RNLEQ 146

                         90       100       110
                 ....*....|....*....|....*....|...
gi 496535546 231 LDVSKN-----EKLNTLFADSTSISNLDVTNNP 258
Cdd:cd21340  147 LDASNNqisdlEELLDLLSSWPSLRELDLTGNP 179
tand_rpt_95 NF012211
tandem-95 repeat; This 95-amino acid repeat occurs in tandem in proteins that may be several ...
 504-634 9.82e-03

tandem-95 repeat; This 95-amino acid repeat occurs in tandem in proteins that may be several thousand amino acids long.


Pssm-ID: 333740 [Multi-domain]  Cd Length: 98  Bit Score: 36.07  E-value: 9.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496535546 504 EDGTITLTKDNIVANDVDTSkagtyhvtykvtdkngasakktitvtvkqntGDLNSAPIISANDVTlnvgdtfdplvNAT 583
Cdd:NF012211   4 EDGSITITQEQLLANASDVD-------------------------------GDDLTVSNVSYSGPT-----------NGT 41

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 496535546 584 ATDKEDGTIILTKDNIIANDVDtskagtyhVTFRVVDKNGAITEKTITVTV 634
Cdd:NF012211  42 VTDNGDGTYTYTPNENFNGDDS--------FTYTVSDGTGATATATVFVTV 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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