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Conserved domains on  [gi|497531955|ref|WP_009846153|]
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MULTISPECIES: carbohydrate ABC transporter permease [Vibrio]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 27-297 3.72e-90

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 269.66  E-value: 3.72e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  27 KILMVMLGILLVVSALITVFPFVWSALLSTRDRSEIFGTGISFAIGDSLAINYAKLLEIMPFWKAMFNSIYVAFLGTTIS 106
Cdd:COG0395   11 RLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 107 LLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPFT--TTPFGIFLMRQHvIAS 184
Cdd:COG0395   91 LLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLafGLPFGIFLLRQF-FRS 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 185 IPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRSVQGIPNTPWGAV 264
Cdd:COG0395  170 IPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLL 249

                        250       260       270
                 ....*....|....*....|....*....|...
gi 497531955 265 MLGTTISILPLVITYLFASKQMISGLTSGAVKG 297
Cdd:COG0395  250 MAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 27-297 3.72e-90

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 269.66  E-value: 3.72e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  27 KILMVMLGILLVVSALITVFPFVWSALLSTRDRSEIFGTGISFAIGDSLAINYAKLLEIMPFWKAMFNSIYVAFLGTTIS 106
Cdd:COG0395   11 RLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 107 LLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPFT--TTPFGIFLMRQHvIAS 184
Cdd:COG0395   91 LLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLafGLPFGIFLLRQF-FRS 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 185 IPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRSVQGIPNTPWGAV 264
Cdd:COG0395  170 IPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLL 249

                        250       260       270
                 ....*....|....*....|....*....|...
gi 497531955 265 MLGTTISILPLVITYLFASKQMISGLTSGAVKG 297
Cdd:COG0395  250 MAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
36-290 2.84e-27

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 107.13  E-value: 2.84e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  36 LLVVSALITVFPFVWSALLSTRDRSEIFGTGISFAIGDSLAINYAKLLE------IMPFWKAMFNSIYVAFLGTTISLLF 109
Cdd:PRK10973  15 MLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIWVngvgnnSAPFGRMLLNSFVMAFSITVGKITV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 110 CSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPFTTTPFGIFLMRQHVIaSIPKEL 189
Cdd:PRK10973  95 SMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFM-TLPDEL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 190 LEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRSV--QGIPNTPWGAVMLG 267
Cdd:PRK10973 174 VEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMiaTGEGTTEWNQVMAA 253

                        250       260
                 ....*....|....*....|...
gi 497531955 268 TTISILPLVITYLFASKQMISGL 290
Cdd:PRK10973 254 MLLTLIPPVVIVLAMQRAFVRGL 276
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 92-274 8.76e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 71.16  E-value: 8.76e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  92 MFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHM-----AVWLP 166
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPglglpALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 167 FTTTPFGIFLMRQHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVI 246
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....*...
gi 497531955 247 TQALRSVQGIPNTPWGAVMLGTTISILP 274
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLL 188
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 112-282 3.35e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 55.38  E-value: 3.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  112 MGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPF-TTTPFGIFLMRQHVIASIPKELL 190
Cdd:pfam00528   4 LGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILAlLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  191 EAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRSVQGIPNTPWGAVMLGTTI 270
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALIL 163

                         170
                  ....*....|..
gi 497531955  271 SILPLVITYLFA 282
Cdd:pfam00528 164 LLLNLLVDILQR 175
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 78-295 5.34e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 38.12  E-value: 5.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955   78 NYAKLLEIMPFWKAMFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIP---PVLSLIPYFM---IV 151
Cdd:TIGR03262  42 NFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPsllPAISLIYLFGnqgLL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  152 KFLGLLDNHMAVW-----LPFTTTPFgIFLMRQHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVF 226
Cdd:TIGR03262 122 KGLLGGFSIYGFWgivigEVFYTFPH-ALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTL 200

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497531955  227 FWNMFMQPLVVLNNPdNYVITQALRSVQGIPNTPWGAVMlgTTISILPLVITYL---FASKQMISGLTSGAV 295
Cdd:TIGR03262 201 VITDFGVPKVIGGDY-NVLATDIYKQVIGQQNFPMGAVV--GVLLLLPALLAFGidrAIQRRQRAQLSSRSV 269
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 27-297 3.72e-90

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 269.66  E-value: 3.72e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  27 KILMVMLGILLVVSALITVFPFVWSALLSTRDRSEIFGTGISFAIGDSLAINYAKLLEIMPFWKAMFNSIYVAFLGTTIS 106
Cdd:COG0395   11 RLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 107 LLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPFT--TTPFGIFLMRQHvIAS 184
Cdd:COG0395   91 LLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLafGLPFGIFLLRQF-FRS 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 185 IPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRSVQGIPNTPWGAV 264
Cdd:COG0395  170 IPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLL 249

                        250       260       270
                 ....*....|....*....|....*....|...
gi 497531955 265 MLGTTISILPLVITYLFASKQMISGLTSGAVKG 297
Cdd:COG0395  250 MAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 20-297 1.76e-54

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 178.42  E-value: 1.76e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  20 RSMFILTKILMVMLGILLVVSALITVFPFVWSALLSTRDRSEIFGTGISFAiGDSLAiNYAKLLEIMPFWKAMFNSIYVA 99
Cdd:COG3833    5 KSRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSLIPE-NFTLE-NYKKLFTETPFLRWFLNSLIVA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 100 FLGTTISLLFCSMGGYAFAVFKFRG-KNVLFGMLVGSMaIPPVLSLIPYFMIVKFLGLLDNHMAVWLPFTTT--PFGIFL 176
Cdd:COG3833   83 VVTAIISVFLAALAAYAFSRFRFKGrKAGLLALLLLQM-FPAFLALVALYLLLSALGLLNTLLGLILVYLGGaiPFNTWL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 177 MRQHvIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRS-VQG 255
Cdd:COG3833  162 MKGY-FDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSfVSD 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 497531955 256 IPNTPWGAVMLGTTISILPLVITYLFASKQMISGLTSGAVKG 297
Cdd:COG3833  241 QRNTNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
36-290 2.84e-27

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 107.13  E-value: 2.84e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  36 LLVVSALITVFPFVWSALLSTRDRSEIFGTGISFAIGDSLAINYAKLLE------IMPFWKAMFNSIYVAFLGTTISLLF 109
Cdd:PRK10973  15 MLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIWVngvgnnSAPFGRMLLNSFVMAFSITVGKITV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 110 CSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPFTTTPFGIFLMRQHVIaSIPKEL 189
Cdd:PRK10973  95 SMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFM-TLPDEL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 190 LEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRSV--QGIPNTPWGAVMLG 267
Cdd:PRK10973 174 VEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMiaTGEGTTEWNQVMAA 253

                        250       260
                 ....*....|....*....|...
gi 497531955 268 TTISILPLVITYLFASKQMISGL 290
Cdd:PRK10973 254 MLLTLIPPVVIVLAMQRAFVRGL 276
malG PRK10998
maltose ABC transporter permease MalG;
92-297 2.68e-21

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 91.31  E-value: 2.68e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  92 MFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLF-GMLVGSMaIPPVLSLIPYFMIVKFLGL------LDNHMAVW 164
Cdd:PRK10998  85 LWNSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLkGMLIFQM-FPAVLSLVALYALFDRLGQyipfigLNTHGGVI 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 165 LPFTTtpfGIFL---MRQHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNP 241
Cdd:PRK10998 164 FAYLG---GIALhvwTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDV 240

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 497531955 242 DNYVITQALRSVQGIPNTPWGAVMLGTTISILPLVITYLFASKQMISGLTSGAVKG 297
Cdd:PRK10998 241 NSYTLAVGMQQYLNPQNYLWGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
31-236 4.17e-19

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 85.19  E-value: 4.17e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  31 VMLGILLVVSALITVFPFVWSALLSTRDRSeIFGTGISFAIGDslaiNYAKLLEIMPFWKAMFNSIYVAFLGTTISLLFc 110
Cdd:COG1175   22 LFLLPALLLLLVFVLYPLLYTLYLSFTDWN-LLGPPPEFVGLD----NYARLFTDPRFWNALGNTLLFTVVSVPLQLVL- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 111 smgGYAFAVF---KFRGKNVLFGMLVGSMAIPPVL-SLIPYFMIVKFLGLLdNHMAVWLPFTTTPF---------GIFLM 177
Cdd:COG1175   96 ---GLLLALLlnrKLRGRGFFRTLFFLPWVISPVVvALIWKWLFNPDYGLL-NALLGALGLEPINWlgdpslalpAVIIV 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497531955 178 R--QHV----------IASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLV 236
Cdd:COG1175  172 TvwKGTgfnmliflagLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYV 242
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 79-231 1.20e-18

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 83.24  E-value: 1.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  79 YAKLLEIMPFWKAMFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLD 158
Cdd:COG1177   50 YAELFSDPRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSG 129

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497531955 159 NHMAVWLPFTT--TPFGIFLMRqHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMF 231
Cdd:COG1177  130 GLWGLILAHVVftLPFVVLVVL-ARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEF 203
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 92-274 8.76e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 71.16  E-value: 8.76e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  92 MFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHM-----AVWLP 166
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPglglpALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 167 FTTTPFGIFLMRQHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVI 246
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....*...
gi 497531955 247 TQALRSVQGIPNTPWGAVMLGTTISILP 274
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLL 188
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 32-278 6.95e-12

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 64.40  E-value: 6.95e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  32 MLGILLVVSALITVFPFVWSALLSTRDRSEIFGTGISFaigdSLAiNYAKLLEIMPFWKAMFNSIYVAFLGTTISLLFCS 111
Cdd:COG1176   14 LLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGF----TLE-NYARLFTDPLYLKVLLRTLWIALLTTLICLLLGY 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 112 MGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLdNHMAVWL-------PFTTTPFGIF--------- 175
Cdd:COG1176   89 PIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLL-NSLLLALglideplRLLYTEFAVViglvyvylp 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 176 ---LMRQHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLvVLNNPDNYVITQALRS 252
Cdd:COG1176  168 fmvLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPA-LLGGGKVLMIGNLIYQ 246

                        250       260
                 ....*....|....*....|....*.
gi 497531955 253 vQGIPNTPWGavmLGTTISILPLVIT 278
Cdd:COG1176  247 -QFLSALNWP---LAAALAVVLLLIV 268
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 79-217 1.02e-11

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 63.85  E-value: 1.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  79 YAKLLEIMPFWKAMFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPV---LSLIPYFMIVK--- 152
Cdd:PRK09500  46 YELLFNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIvmaISLLVLFMLLGiql 125

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497531955 153 -FLGLLDNHMAVWLPFTT-TPFGIFlmrqhviASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALA 217
Cdd:PRK09500 126 gFWSLLFAHITFCLPFVVvTVYSRL-------KGFDVRMLEAAKDLGASEFTILRKIILPLALPAVA 185
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
88-226 2.08e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 64.03  E-value: 2.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  88 FWKAMFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPF 167
Cdd:COG1178   52 LWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALFGL 131

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497531955 168 TT----TPFGIFLMrqHVI--------------ASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVF 226
Cdd:COG1178  132 EPpdiyGLGGIILV--LVLfnypyvylllraalRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLL 206
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 88-218 9.61e-10

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 58.22  E-value: 9.61e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  88 FWKAMFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVW-LP 166
Cdd:COG0555   52 VLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLgIK 131

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497531955 167 FTTTPFGI----------FLMR--QHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALAT 218
Cdd:COG0555  132 VAFTPLGIvlaqtfvslpFVVRtvQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLT 195
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
27-225 1.52e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 58.25  E-value: 1.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  27 KILMVMLGILLVVSALITVFPFVWSALLSTRDRSEIFGtgisfaigdslaiNYAKLLEIMPFWKAMFNSIYVAFLGTTIS 106
Cdd:COG1178  288 WLALALCLLLVLLGLLLPLLALLLWSLTKALDDNLTLD-------------NYRFVLLDPSLLRALLNSLLLALLAALLA 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 107 LLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPP-VLSLIPYFMIVKFLGLLDNHMAVWLPFTTT----PFGIFLMRQhV 181
Cdd:COG1178  355 VLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGiVLGLGLLLLFNRPLPLLLYGTLAILVLAYVvrflPFALRSLEA-A 433

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 497531955 182 IASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFV 225
Cdd:COG1178  434 LAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFV 477
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 112-282 3.35e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 55.38  E-value: 3.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  112 MGGYAFAVFKFRGKNVLFGMLVGSMAIPPVLSLIPYFMIVKFLGLLDNHMAVWLPF-TTTPFGIFLMRQHVIASIPKELL 190
Cdd:pfam00528   4 LGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILAlLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  191 EAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNMFMQPLVVLNNPDNYVITQALRSVQGIPNTPWGAVMLGTTI 270
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALIL 163

                         170
                  ....*....|..
gi 497531955  271 SILPLVITYLFA 282
Cdd:pfam00528 164 LLLNLLVDILQR 175
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
35-231 5.65e-06

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 46.74  E-value: 5.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  35 ILLVVSALITVFPFVW---SALLSTRDRSEIFGTGISFAIGDSLAINYAKLLEIMPFWKAMFNSIYVAFLGTTISLLFCS 111
Cdd:PRK10561   1 LLVAPQLIITVIFFIWpagEALWYSLQSVDPFGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 112 MGGYAFavfkfRGKNVLFGMLVGSMAIPPVLSLIPYF--------MIVKFLGLLD---NH-------------MAVWLPF 167
Cdd:PRK10561  81 LVDYVV-----RGSRFYQTLMLLPYAVAPAVAAVLWIflfnpgrgLITHFLAEFGydwNHaqnsgqamflvvfASVWKQI 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497531955 168 TTTpfgiFLMRQHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVF-FWNMF 231
Cdd:PRK10561 156 SYN----FLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYaFFDTF 216
cysT CHL00187
sulfate transport protein; Provisional
 95-218 1.73e-05

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 45.01  E-value: 1.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  95 SIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPV---LSLIPYFMIVKFLGLLDNHMAVWLPFTttP 171
Cdd:CHL00187  60 TLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDAAVDLPFALPTSvagLTLATVYGDNGWIGHLLSHLGIQIVFT--K 137

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 497531955 172 FGI----------FLMR--QHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALAT 218
Cdd:CHL00187 138 LGVllamifvsfpFVVRtiQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLT 196
modB PRK09421
molybdate ABC transporter permease subunit;
89-224 1.16e-04

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 42.60  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  89 WKAMFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIPPVlsLIPYFMIVKF-----LG-LLDNHMA 162
Cdd:PRK09421   8 WQAVLLSLKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPV--VTGYLLLISMgrrgfIGqWLYEWFG 85

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497531955 163 VWLPFTTTP-------FGIFLMRQHV---IASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQF 224
Cdd:PRK09421  86 ISFAFSWRGaalaaavMAFPLMVRAIrlsLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAF 157
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 182-221 1.90e-04

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 42.38  E-value: 1.90e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 497531955 182 IASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAI 221
Cdd:COG4209  200 ITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLI 239
malF PRK10999
maltose ABC transporter permease MalF;
184-269 1.97e-04

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 42.64  E-value: 1.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955 184 SIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVFFWNmfmqplvvlnnpdNYVITQALrsVQGIPNtpwga 263
Cdd:PRK10999 400 AIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFN-------------NFVLIQLL--TNGGPD----- 459


                 ....*.
gi 497531955 264 vMLGTT 269
Cdd:PRK10999 460 -MIGTT 464
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 78-295 5.34e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 38.12  E-value: 5.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955   78 NYAKLLEIMPFWKAMFNSIYVAFLGTTISLLFCSMGGYAFAVFKFRGKNVLFGMLVGSMAIP---PVLSLIPYFM---IV 151
Cdd:TIGR03262  42 NFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPsllPAISLIYLFGnqgLL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531955  152 KFLGLLDNHMAVW-----LPFTTTPFgIFLMRQHVIASIPKELLEAAKLDGAGEFRTYWSVVLPLMKPALATLAIVQFVF 226
Cdd:TIGR03262 122 KGLLGGFSIYGFWgivigEVFYTFPH-ALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTL 200

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497531955  227 FWNMFMQPLVVLNNPdNYVITQALRSVQGIPNTPWGAVMlgTTISILPLVITYL---FASKQMISGLTSGAV 295
Cdd:TIGR03262 201 VITDFGVPKVIGGDY-NVLATDIYKQVIGQQNFPMGAVV--GVLLLLPALLAFGidrAIQRRQRAQLSSRSV 269
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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