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Conserved domains on  [gi|497896961|ref|WP_010211117|]
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MULTISPECIES: crotonase/enoyl-CoA hydratase family protein [Pseudomonas]

Protein Classification

crotonase/enoyl-CoA hydratase family protein( domain architecture ID 10793018)

crotonase/enoyl-CoA hydratase family protein similar to Ruegeria pomeroyi methylthioacryloyl-CoA hydratase which is involved in the assimilation of dimethylsulphoniopropionate (DMSP); it catalyzes both, the hydration and the hydrolysis of 3-(methylthio)acryloyl-CoA (MTA-CoA) to acetaldehyde, CO2, MeSH, and CoA

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
5-256 1.12e-110

crotonase/enoyl-CoA hydratase family protein;


:

Pssm-ID: 181254  Cd Length: 255  Bit Score: 319.27  E-value: 1.12e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   5 NYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREW 84
Cdd:PRK08150   2 SLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGEGMHHSRRW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 HKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGR 164
Cdd:PRK08150  82 HRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGR 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 165 TLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIRTQDRL 244
Cdd:PRK08150 162 VYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMAAVAQSAPEAKERL 241
                        250
                 ....*....|..
gi 497896961 245 ADFLDRKKDKIQ 256
Cdd:PRK08150 242 RAFLEKKAAKVK 253
 
Name Accession Description Interval E-value
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
5-256 1.12e-110

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 319.27  E-value: 1.12e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   5 NYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREW 84
Cdd:PRK08150   2 SLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGEGMHHSRRW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 HKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGR 164
Cdd:PRK08150  82 HRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGR 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 165 TLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIRTQDRL 244
Cdd:PRK08150 162 VYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMAAVAQSAPEAKERL 241
                        250
                 ....*....|..
gi 497896961 245 ADFLDRKKDKIQ 256
Cdd:PRK08150 242 RAFLEKKAAKVK 253
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-252 6.53e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 195.00  E-value: 6.53e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAF-RE 83
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEadPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFaRG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  84 WHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTG 163
Cdd:COG1024   81 LQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 164 RTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIRTQDR 243
Cdd:COG1024  161 RRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREG 240

                 ....*....
gi 497896961 244 LADFLDRKK 252
Cdd:COG1024  241 IAAFLEKRK 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
7-197 1.69e-54

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 174.29  E-value: 1.69e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNI--PDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNV--QAFR 82
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAeaDPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEarAFIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  83 EWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLT 162
Cdd:cd06558   81 ELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLT 160
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 497896961 163 GRTLYAKESYERGVAQYLVPVGQALLKATELAHKI 197
Cdd:cd06558  161 GRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
13-202 8.47e-35

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 125.16  E-value: 8.47e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   13 GAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREWHKTFEL 90
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTdpSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   91 IQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLYAKE 170
Cdd:pfam00378  84 LYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQE 163
                         170       180       190
                  ....*....|....*....|....*....|..
gi 497896961  171 SYERGVAQYLVPVGQALLKATELAHKIAGNLP 202
Cdd:pfam00378 164 ALKWGLVDKVVPEDQLLDEARELAEKLAEKSP 195
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
6-196 1.95e-26

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 108.00  E-value: 1.95e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961    6 YLDVSVDGAVLMVGLNRPQ-KRNAMSLEVMHELRDTFTNI--PDGIGAAVLYSTSQH-FCTGLDLSEIR-DQSVIDNVQA 80
Cdd:TIGR02441  14 HRHYEVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELwtNEAIKSAVLISGKPGsFVAGADIQMIAaCKTAQEVTQL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   81 FREWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVV--DDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTD 158
Cdd:TIGR02441  94 SQEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIAtkDRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALD 173
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 497896961  159 MMLTGRTLYAKESYERGVAQYLV-PVGQALLKATELAHK 196
Cdd:TIGR02441 174 MMLTGKKIRADRAKKMGIVDQLVdPLGPGLKPAEENTIE 212
 
Name Accession Description Interval E-value
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
5-256 1.12e-110

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 319.27  E-value: 1.12e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   5 NYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREW 84
Cdd:PRK08150   2 SLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGEGMHHSRRW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 HKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGR 164
Cdd:PRK08150  82 HRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGR 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 165 TLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIRTQDRL 244
Cdd:PRK08150 162 VYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMAAVAQSAPEAKERL 241
                        250
                 ....*....|..
gi 497896961 245 ADFLDRKKDKIQ 256
Cdd:PRK08150 242 RAFLEKKAAKVK 253
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-252 6.53e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 195.00  E-value: 6.53e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAF-RE 83
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEadPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFaRG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  84 WHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTG 163
Cdd:COG1024   81 LQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 164 RTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIRTQDR 243
Cdd:COG1024  161 RRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREG 240

                 ....*....
gi 497896961 244 LADFLDRKK 252
Cdd:COG1024  241 IAAFLEKRK 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
7-197 1.69e-54

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 174.29  E-value: 1.69e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNI--PDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNV--QAFR 82
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAeaDPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEarAFIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  83 EWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLT 162
Cdd:cd06558   81 ELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLT 160
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 497896961 163 GRTLYAKESYERGVAQYLVPVGQALLKATELAHKI 197
Cdd:cd06558  161 GRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
PLN02600 PLN02600
enoyl-CoA hydratase
12-252 5.95e-40

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 138.78  E-value: 5.95e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  12 DGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDGIGAAVLY---STSQHFCTGLDLSEIRDQSVIDnVQAF-REWHKT 87
Cdd:PLN02600   2 DSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMlrsSVPGVFCAGADLKERRKMSPSE-VQKFvNSLRST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  88 FELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLY 167
Cdd:PLN02600  81 FSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 168 AKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVssdIRTQDR---L 244
Cdd:PLN02600 161 AREAASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQV---LKTKDRlegL 237

                 ....*...
gi 497896961 245 ADFLDRKK 252
Cdd:PLN02600 238 AAFAEKRK 245
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
5-228 1.82e-38

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 135.15  E-value: 1.82e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   5 NYLDVSVDGAVLMVGLNRPQKrNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIrdQSVIDNVQA-- 80
Cdd:PRK07658   2 KFLSVRVEDHVAVITLNHPPA-NALSSQVLHELSELLDQVEkdDNVRVVVIHGEGRFFSAGADIKEF--TSVTEAEQAte 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  81 -FREWHKTFELI-QFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTD 158
Cdd:PRK07658  79 lAQLGQVTFERVeKFSK-PVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALE 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 159 MMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEA 228
Cdd:PRK07658 158 MMLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREA 227
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
1-228 5.69e-38

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 133.69  E-value: 5.69e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   1 MSGKNYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDL------------ 66
Cdd:PRK07799   1 MEGGPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDndPDIRSCILTGAGGAFCAGMDLkaatkkppgdsf 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  67 -SEIRDQSVIDNVQAFREWHKtfeliqfgkvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASV 145
Cdd:PRK07799  81 kDGSYDPSRIDALLKGRRLTK----------PLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAV 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 146 RFPRIAGIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMtnyAVTHVLPRIVDQSQqdglM 225
Cdd:PRK07799 151 RLVRQIPYTVACDLLLTGRHITAAEAKEIGLIGHVVPDGQALDKALELAELINANGPL---AVQAILRTIRETEG----M 223

                 ...
gi 497896961 226 TEA 228
Cdd:PRK07799 224 HEN 226
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
11-244 2.55e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 129.47  E-value: 2.55e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  11 VDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNI---PDgIGAAVLYSTSQH-FCTGLDLSEIRDQSVIDNVQAFREWHK 86
Cdd:PRK07657  10 VTPHVVKITLNRPRAANALSLALLEELQNILTQIneeAN-VRVVILTGAGEKaFCAGADLKERAGMNEEQVRHAVSLIRT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  87 TFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTL 166
Cdd:PRK07657  89 TMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRI 168
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497896961 167 YAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVssdIRTQDRL 244
Cdd:PRK07657 169 SAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGT---IPTKDRL 243
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
7-198 3.07e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 126.52  E-value: 3.07e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIrDQSVIDNVQAFREW 84
Cdd:PRK06688   7 LLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATdpAVRVVVLTGAGRAFSAGGDIKDF-PKAPPKPPDELAPV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 HKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGR 164
Cdd:PRK06688  86 NRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGE 165
                        170       180       190
                 ....*....|....*....|....*....|....
gi 497896961 165 TLYAKESYERGVAQYLVPVGQALLKATELAHKIA 198
Cdd:PRK06688 166 PLSAEEALRIGLVNRVVPAAELDAEADAQAAKLA 199
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
13-202 8.47e-35

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 125.16  E-value: 8.47e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   13 GAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREWHKTFEL 90
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTdpSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   91 IQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLYAKE 170
Cdd:pfam00378  84 LYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQE 163
                         170       180       190
                  ....*....|....*....|....*....|..
gi 497896961  171 SYERGVAQYLVPVGQALLKATELAHKIAGNLP 202
Cdd:pfam00378 164 ALKWGLVDKVVPEDQLLDEARELAEKLAEKSP 195
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
9-237 7.89e-32

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 117.40  E-value: 7.89e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELR---DTFTNIPDgIGAAVLYSTSQHFCTGLDLSE-IRDQSVIDNVQAF--- 81
Cdd:PRK08252   7 VERRGRVLIITINRPEARNAVNAAVAQGLAaalDELDADPD-LSVGILTGAGGTFCAGMDLKAfARGERPSIPGRGFggl 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  82 --REWHKtfeliqfgkvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDM 159
Cdd:PRK08252  86 teRPPRK----------PLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMEL 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497896961 160 MLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEA-LIAAVVSSD 237
Cdd:PRK08252 156 ALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQReLIAPVFTSA 234
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
9-199 2.25e-31

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 116.53  E-value: 2.25e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQA------ 80
Cdd:PRK08259   7 VERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDadDAASVAVLWGAGGTFCAGADLKAVGTGRGNRLHPSgdgpmg 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  81 -FRewhktfelIQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFslpeamrGLY---VGV----GASVRFPRIAG 152
Cdd:PRK08259  87 pSR--------MRLSK-PVIAAVSGYAVAGGLELALWCDLRVAEEDAVF-------GVFcrrWGVplidGGTVRLPRLIG 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 497896961 153 IALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAG 199
Cdd:PRK08259 151 HSRAMDLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAA 197
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
9-203 1.19e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 111.98  E-value: 1.19e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIrdQSVIDNvQAFR---E 83
Cdd:PRK06563   3 RERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEadDELRVAVLFAHGEHFTAGLDLADV--APKLAA-GGFPfpeG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  84 WHKTFELI--QFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMML 161
Cdd:PRK06563  80 GIDPWGTVgrRLSK-PLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLL 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 497896961 162 TGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPM 203
Cdd:PRK06563 159 TGDEFDAQEALRLGLVQEVVPPGEQLERAIELAERIARAAPL 200
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
7-232 1.72e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 111.60  E-value: 1.72e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSE-----------IRDQS 73
Cdd:PRK06190   6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADadDDVDVVVLTGADPAFCAGLDLKElggdgsaygaqDALPN 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  74 VIDNVQAFRewhktfeliqfgkVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGI 153
Cdd:PRK06190  86 PSPAWPAMR-------------KPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGI 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497896961 154 ALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAA 232
Cdd:PRK06190 153 GRARRMSLTGDFLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEAAR 231
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
12-214 1.11e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 109.36  E-value: 1.11e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  12 DGAVLMVGLNRPQKRNAMSL---EVMHELRDTFTNIPDGIGAAVLYSTSQHFCTGLDLSEI--RDQSVIDNvQAFREWHK 86
Cdd:PRK06494  11 KGHVTIVTLNRPEVMNALHLdahFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQaaGGKRGWPE-SGFGGLTS 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  87 TFELIQfgkvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTL 166
Cdd:PRK06494  90 RFDLDK----PIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRV 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 497896961 167 YAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPR 214
Cdd:PRK06494 166 TAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAVYR 213
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
1-203 1.84e-28

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 109.07  E-value: 1.84e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   1 MSGKNYLdVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLY-STSQHFCTGLDLSEIRDQSVIDN 77
Cdd:PRK05809   1 MELKNVI-LEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIEndDNVYAVILTgAGEKAFVAGADISEMKDLNEEEG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  78 VQAFREWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMT 157
Cdd:PRK05809  80 RKFGLLGNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAK 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 497896961 158 DMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPM 203
Cdd:PRK05809 160 ELIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALANKIAANAPI 205
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
1-199 1.96e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 108.59  E-value: 1.96e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   1 MSGKNYLdVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFT--NIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNV 78
Cdd:PRK05862   1 MAYETIL-VETRGRVGLITLNRPKALNALNDALMDELGAALAafDADEGIGAIVITGSEKAFAAGADIKEMADLSFMDVY 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  79 QA--FREWHKtfelIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALM 156
Cdd:PRK05862  80 KGdyITNWEK----VARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKA 155
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 497896961 157 TDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAG 199
Cdd:PRK05862 156 MDLCLTGRMMDAAEAERAGLVSRVVPADKLLDEALAAATTIAS 198
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
7-227 6.11e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 107.44  E-value: 6.11e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLmVGLNRPQKRNAMSLEVMHELRDTFT--NIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQafREW 84
Cdd:PRK08138  11 LERPADGVAL-LRLNRPEARNALNMEVRQQLAEHFTelSEDPDIRAIVLTGGEKVFAAGADIKEFATAGAIEMYL--RHT 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 HKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGR 164
Cdd:PRK08138  88 ERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGC 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497896961 165 TLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTE 227
Cdd:PRK08138 168 MVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALE 230
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
1-224 7.45e-28

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 107.37  E-value: 7.45e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   1 MSGKNYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNI--PDGIGAAVLYSTSQHFCTGLDL-------SEIRD 71
Cdd:PRK06142   2 MTTYESFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLdaDPEVRAVVLSGSGKHFSYGIDLpamagvfGQLGK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  72 QSVIDNVQAFR----EWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRF 147
Cdd:PRK06142  82 DGLARPRTDLRreilRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRL 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497896961 148 PRIAGIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKAT-ELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGL 224
Cdd:PRK06142 162 PRIIGDGHLRELALTGRDIDAAEAEKIGLVNRVYDDADALLAAAhATAREIAAKSPLAVRGTKEVLDYMRDHRVADGL 239
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
9-204 1.12e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 106.26  E-value: 1.12e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD-GIGAAVLYSTSQHFCTGLDLSEirdqsvidnvQAFRE--WH 85
Cdd:PRK07854   4 VTRDGQVLTIELQRPERRNALNAELCEELREAVRKAVDeSARAIVLTGQGTVFCAGADLSG----------DVYADdfPD 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  86 KTFEL---IQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLT 162
Cdd:PRK07854  74 ALIEMlhaIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLG 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 497896961 163 GRTLYAKESYERGVAQYLVPVGQALlkatELAHKIAGNLPMT 204
Cdd:PRK07854 154 AEKLTAEQALATGMANRIGTLADAQ----AWAAEIAGLAPLA 191
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
12-224 2.71e-27

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 105.93  E-value: 2.71e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  12 DGAVLMVGLNRPqKRNAMSLEVMHELRDTFTNI---PDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREWHKTF 88
Cdd:PRK03580  10 NGSILEITLDRP-KANAIDAKTSFAMGEVFLNFrddPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  89 ELIQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLYA 168
Cdd:PRK03580  89 EIFDLDK-PVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDA 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 497896961 169 KESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGL 224
Cdd:PRK03580 168 EEALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAY 223
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
6-196 1.95e-26

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 108.00  E-value: 1.95e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961    6 YLDVSVDGAVLMVGLNRPQ-KRNAMSLEVMHELRDTFTNI--PDGIGAAVLYSTSQH-FCTGLDLSEIR-DQSVIDNVQA 80
Cdd:TIGR02441  14 HRHYEVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELwtNEAIKSAVLISGKPGsFVAGADIQMIAaCKTAQEVTQL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   81 FREWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVV--DDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTD 158
Cdd:TIGR02441  94 SQEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIAtkDRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALD 173
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 497896961  159 MMLTGRTLYAKESYERGVAQYLV-PVGQALLKATELAHK 196
Cdd:TIGR02441 174 MMLTGKKIRADRAKKMGIVDQLVdPLGPGLKPAEENTIE 212
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
9-256 2.41e-26

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 103.31  E-value: 2.41e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTF--TNIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFRE--W 84
Cdd:PRK09674   6 VSRQQRVLLLTLNRPEARNALNNALLTQLVNELeaAATDTSIGVCVITGNARFFAAGADLNEMAEKDLAATLNDPRPqlW 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 HKtfeLIQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGR 164
Cdd:PRK09674  86 QR---LQAFNK-PLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGE 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 165 TLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTE----ALIAAvvssdirT 240
Cdd:PRK09674 162 SITAQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQErqlfTLLAA-------T 234
                        250
                 ....*....|....*....
gi 497896961 241 QDR---LADFLDRKKDKIQ 256
Cdd:PRK09674 235 EDRhegISAFLEKRTPDFK 253
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
10-224 1.60e-25

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 101.52  E-value: 1.60e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  10 SVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNI---PDgIGAAVLYSTSQHFCTGLDL---SEIRDQSVI-DNVQAFR 82
Cdd:PLN02664  13 SPNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLdqnPN-VSVIILSGAGDHFCSGIDLktlNSISEQSSSgDRGRSGE 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  83 EWHKTFELIQFG-------KVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIAL 155
Cdd:PLN02664  92 RLRRKIKFLQDAitaieqcRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGN 171
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 156 MTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATEL-AHKIAGNLPMTNYAVTHVLPRIVDQSQQDGL 224
Cdd:PLN02664 172 AMELALTGRRFSGSEAKELGLVSRVFGSKEDLDEGVRLiAEGIAAKSPLAVTGTKAVLLRSRELSVEQGL 241
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
7-239 1.79e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 100.84  E-value: 1.79e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTS-QHFCTGLDLSEIRDQSVIDNVQAF-R 82
Cdd:PRK06144  10 LLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAadPSIRAVVLRGAGdKAFVAGTDIAQFRAFSTAEDAVAYeR 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  83 EWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAmRGLyvGVGASVR-FPRIA---GIALMTD 158
Cdd:PRK06144  90 RIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPIA-RTL--GNCLSMSnLARLVallGAARVKD 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 159 MMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGlmtEALIAAV-VSSD 237
Cdd:PRK06144 167 MLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDG---DDLIRMCyMSED 243

                 ..
gi 497896961 238 IR 239
Cdd:PRK06144 244 FR 245
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
7-252 5.54e-25

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 99.77  E-value: 5.54e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPqKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEirDQSVIDNVQAF--- 81
Cdd:PRK06495   6 LKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISErpDVRVVVLTGAGKVFCAGADLKG--RPDVIKGPGDLrah 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  82 -REWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVR-FPRiagiALMTDM 159
Cdd:PRK06495  83 nRRTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLAGGGKHAMRlFGH----SLTRRM 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 160 MLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIR 239
Cdd:PRK06495 159 MLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKTED 238
                        250
                 ....*....|...
gi 497896961 240 TQDRLADFLDRKK 252
Cdd:PRK06495 239 AKEAQRAFLEKRP 251
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
15-199 3.31e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 97.98  E-value: 3.31e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  15 VLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSE----------------IRDQSVID 76
Cdd:PRK05864  20 IALITLNRPERMNSMAFDVMVPLKEALAEVSydNSVRVVVLTGAGRGFSSGADHKSagvvphvegltrptyaLRSMELLD 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  77 NV-QAFREWHKtfeliqfgkvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVG-VGASVRFPRIAGIA 154
Cdd:PRK05864 100 DViLALRRLHQ----------PVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASeLGLSYLLPRAIGSS 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 497896961 155 LMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAG 199
Cdd:PRK05864 170 RAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAG 214
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
5-202 6.82e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 96.96  E-value: 6.82e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   5 NYLDVSVDGAVLMVGLNRPQKRNAMS-LEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNV--- 78
Cdd:PRK09245   3 DFLLVERDGHIVTLTMNRPETRNALSdNDAVDALVAACAAINAdrSVRAVILTGAGTAFSSGGNVKDMRARVGAFGGspa 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  79 ---QAFREWHKTFELIQFG-KVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIA 154
Cdd:PRK09245  83 dirQGYRHGIQRIPLALYNlEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMA 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 497896961 155 LMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLP 202
Cdd:PRK09245 163 RAAEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPP 210
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
12-253 8.10e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 96.37  E-value: 8.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  12 DGAVLMVgLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQH-FCTGLDLSEIRDqSVIDNVQ-AFREWHK- 86
Cdd:PRK05980  11 DGIALLT-LNRPEKLNALNYALIDRLLARLDAIEVdeSVRAVILTGAGDRaFSAGADIHEFSA-SVAAGADvALRDFVRr 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  87 ----TFELIQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLT 162
Cdd:PRK05980  89 gqamTARLEAFPK-PVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLT 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 163 GRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIRTQD 242
Cdd:PRK05980 168 GDAFSAERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLRE 247
                        250
                 ....*....|.
gi 497896961 243 RLADFLDRKKD 253
Cdd:PRK05980 248 GLAAWIERRRP 258
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
7-227 3.25e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 94.95  E-value: 3.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIrDQSVIDNVQAFREW 84
Cdd:PRK07509   5 VSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKkdRGIRAVILSGEGGAFCAGLDVKSV-ASSPGNAVKLLFKR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 -HKTFELIQFG-------KVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALM 156
Cdd:PRK07509  84 lPGNANLAQRVslgwrrlPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVA 163
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497896961 157 TDMMLTGRTLYAKESYERGVAQYLVPvgQALLKATELAHKIAGNLPMTNYAVTHVLPRIVDQSQQDGLMTE 227
Cdd:PRK07509 164 RELTYTARVFSAEEALELGLVTHVSD--DPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARE 232
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
7-212 2.55e-22

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 92.72  E-value: 2.55e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIrdqsvIDNVQAFRew 84
Cdd:PRK08258  19 FLWEVDDGVATITLNRPERKNPLTFESYAELRDLFRELVyaDDVKAVVLTGAGGNFCSGGDVHEI-----IGPLTKMD-- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 hkTFELIQF----GKV---------PVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLpeamrgLYVGV-------GAS 144
Cdd:PRK08258  92 --MPELLAFtrmtGDLvkamracpqPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAF------LFTRVglagadmGAC 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497896961 145 VRFPRIAGIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAgNLPMTNYAVTHVL 212
Cdd:PRK08258 164 ALLPRIIGQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLA-AGPTFAHGMTKTM 230
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
7-252 3.17e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 92.30  E-value: 3.17e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFT--NIPDGIGAAVLYSTSQHFCTGLDLSEIR---DQSVIDNVQAF 81
Cdd:PRK05995   6 LEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRalDADDSVRAVVLAGAGKAFCAGADLNWMKkmaGYSDDENRADA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  82 REWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVrFPRIAGIALMTDMML 161
Cdd:PRK05995  86 RRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPY-VIRAMGERAARRYFL 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 162 TGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMT----NYAVTHVLPRIVDQSqqdgLM--TEALIAAVVS 235
Cdd:PRK05995 165 TAERFDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAvragKRLVRDVAGRPIDAA----LIadTASRIALIRA 240
                        250
                 ....*....|....*..
gi 497896961 236 SDiRTQDRLADFLDRKK 252
Cdd:PRK05995 241 TE-EAREGVAAFLEKRK 256
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
7-200 5.17e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 92.38  E-value: 5.17e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTF--TNIPDGIGAAVLYSTSQHFCTGLDLS---------------EI 69
Cdd:PRK08260   6 IRYDVADGIATITLNRPDKLNAFTVTMARELIEAFdaADADDAVRAVIVTGAGRAFCAGADLSaggntfdldaprtpvEA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  70 RDQSVIDNVQ-AFREWHKTFELIQFG-KVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLyVGVGASVRF 147
Cdd:PRK08260  86 DEEDRADPSDdGVRDGGGRVTLRIFDsLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGI-VPEAASSWF 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 497896961 148 -PRIAGIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGN 200
Cdd:PRK08260 165 lPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADN 218
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
82-196 2.17e-21

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 93.04  E-value: 2.17e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  82 REWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSA--FFSLPEAMRGLYVGVGASVRFPRIAGIALMTDM 159
Cdd:PRK11154  88 RQGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPktVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDM 167
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 497896961 160 MLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHK 196
Cdd:PRK11154 168 ILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAKK 204
PLN02888 PLN02888
enoyl-CoA hydratase
15-200 7.47e-21

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 88.66  E-value: 7.47e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  15 VLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLS---EIRDQSVIDnvqafrEWHKTFE 89
Cdd:PLN02888  20 IATITINRPKALNALTRPMMVELAAAFKRLDedDSVKVIILTGSGRAFCSGVDLTaaeEVFKGDVKD------VETDPVA 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  90 LIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLYAK 169
Cdd:PLN02888  94 QMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAE 173
                        170       180       190
                 ....*....|....*....|....*....|.
gi 497896961 170 ESYERGVAQYLVPVGQALLKATELAHKIAGN 200
Cdd:PLN02888 174 TAERWGLVNHVVEESELLKKAREVAEAIIKN 204
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
7-202 1.16e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 88.13  E-value: 1.16e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDL---SEIRDQSVIDNVQAF 81
Cdd:PRK07511   5 LLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAErdPSIRAVVLTGAGGFFCAGGNLnrlLENRAKPPSVQAASI 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  82 REWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMML 161
Cdd:PRK07511  85 DGLHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLL 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 497896961 162 TGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLP 202
Cdd:PRK07511 165 EGKPISAERLHALGVVNRLAEPGQALAEALALADQLAAGSP 205
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
12-200 4.21e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 86.68  E-value: 4.21e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  12 DGAVLMVGLNRPQKRNAMSLEVMHELRDTF--TNIPDGIGAAVLYSTSQHFCTGLDLSEI---------RDQSVIDNVQA 80
Cdd:PRK06210  13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMdrAEADPAVRVIVLTGAGRGFCAGADMGELqtidpsdgrRDTDVRPFVGN 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  81 FR-EWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDM 159
Cdd:PRK06210  93 RRpDYQTRYHFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANALDL 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 497896961 160 MLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGN 200
Cdd:PRK06210 173 LLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARN 213
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
9-252 4.84e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 83.99  E-value: 4.84e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLE----VMHELRDTFTNipDGIGAAVLYSTSQH-FCTGLDLSEIRDQSVIDN-VQAFR 82
Cdd:PRK06127  15 AEKTGGLGRITFNNPARHNAMSLDmweaLPQALAAAEDD--DAIRVVVLTGAGEKaFVSGADISQFEESRSDAEaVAAYE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  83 EWHKT-FELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMML 161
Cdd:PRK06127  93 QAVEAaQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFY 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 162 TGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIV-DQSQQDGLMTEALIAAVVSSDIRT 240
Cdd:PRK06127 173 TARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAIAELLkDEPERDMAACQALVAACFDSEDYR 252
                        250
                 ....*....|..
gi 497896961 241 QDRLAdFLDRKK 252
Cdd:PRK06127 253 EGRAA-FMEKRK 263
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
10-204 1.08e-18

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 82.68  E-value: 1.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  10 SVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQA-FREWHK 86
Cdd:PRK08139  16 EDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAadPSVRVVVLAAAGKAFCAGHDLKEMRAARGLAYFRAlFARCSR 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  87 TFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYV---GVGASVRFPRIAGIalmtDMMLTG 163
Cdd:PRK08139  96 VMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFCstpMVALSRNVPRKQAM----EMLLTG 171
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 497896961 164 RTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMT 204
Cdd:PRK08139 172 EFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAA 212
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
6-202 1.23e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 82.66  E-value: 1.23e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   6 YLDVSVDGAVLMVGLNRPQKrNAMSLEVMHELRDTFT--NIPDGIGAAVLysTSQ---HFCTGLDLSEIRD---QSVIDN 77
Cdd:PRK09076   4 ELDLEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLelNADKDVYALVI--TGDgekFFSAGADLNLFADgdkAVAREM 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  78 VQAFREwhkTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMT 157
Cdd:PRK09076  81 ARRFGE---AFEALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAK 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 497896961 158 DMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLP 202
Cdd:PRK09076 158 RMILCGERVDAATALRIGLVEEVVEKGEAREAALALAQKVANQSP 202
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
9-198 2.64e-18

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 81.70  E-value: 2.64e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDG---IGAAVLYSTSQHFCTGLDLS----EIRDQSVIDNVQAF 81
Cdd:PRK05981   8 LDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGkaeVRCLVLTGAGRGFCTGANLQgrgsGGRESDSGGDAGAA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  82 RE--WHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSlpEAMR--GLYVGVGASVRFPRIAGIALMT 157
Cdd:PRK05981  88 LEtaYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFL--QAFRriGLVPDGGSTWLLPRLVGKARAM 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 497896961 158 DMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIA 198
Cdd:PRK05981 166 ELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELA 206
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
6-212 4.42e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 81.55  E-value: 4.42e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   6 YLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSE---IRD-QSVIDNVQ 79
Cdd:PRK08290   5 YVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEadDAVRVIVLAGAGKHFSAGHDLGSgtpGRDrDPGPDQHP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  80 AF---------------REWHKTFELIQ----FGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLyvg 140
Cdd:PRK08290  85 TLwwdgatkpgveqryaREWEVYLGMCRrwrdLPK-PTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI--- 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 141 vgASVRF--------PRIAgialmTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAG----NLPMTNYAV 208
Cdd:PRK08290 161 --PGVEYfahpwelgPRKA-----KELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAmppfGLRLTKRAV 233

                 ....
gi 497896961 209 THVL 212
Cdd:PRK08290 234 NQTL 237
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
9-199 1.63e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 79.38  E-value: 1.63e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREWHK 86
Cdd:PRK05870   7 LDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEAdpDVHALVVTGAGKAFCAGADLTALGAAPGRPAEDGLRRIYD 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  87 TFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTL 166
Cdd:PRK05870  87 GFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRF 166
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 497896961 167 YAKESYERGVAQYLV--PVGQALlkatELAHKIAG 199
Cdd:PRK05870 167 DAEAAVRHGLALMVAddPVAAAL----ELAAGPAA 197
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
8-217 1.04e-16

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 77.36  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   8 DVSVDGAVLMVGLNRPQKRNAMSLEV---MHELRDTFTNIPDgIGAAVLYSTSQHFCTGLDLSE----IRDQSVIDNVQA 80
Cdd:PRK09120  11 KVEVEDGIAWVTLNRPEKRNAMSPTLnreMIDVLDALEFDDD-AGVLVLTGAGDAWSAGMDLKEyfreTDAQPEILQERI 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  81 FREWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASvrfpriagiALMTDMM 160
Cdd:PRK09120  90 RREAYGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVS---------KAMADTV 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497896961 161 ---------LTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAVTHVLPRIVD 217
Cdd:PRK09120 161 ghrdalyyiMTGETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGFKRVRE 226
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
6-208 3.76e-16

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 75.83  E-value: 3.76e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   6 YLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELR---DTFTNipDGIGAAVLYST--SQHFCTGLDLSEI----RD----- 71
Cdd:PRK11423   5 YVNVVTINKIATITFNNPAKRNALSKVLIDDLMqalSDLNR--PEIRVVILRAPsgSKVWSAGHDIHELpsggRDplsyd 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  72 ---QSVIDNVQAFrewhktfeliqfgKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFP 148
Cdd:PRK11423  83 dplRQILRMIQKF-------------PKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFT 149
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 149 RIAGIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPMTNYAV 208
Cdd:PRK11423 150 NDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVI 209
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
22-258 3.37e-15

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 73.41  E-value: 3.37e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  22 RPQKRNAMSLEVMHELRDTFTNIPDGIGAA-------VLYS-TSQHFCTGLDLSEIRD--------------QSVIDNVQ 79
Cdd:PRK08788  33 RAQPRPCFNLELLDDIMNLQRAIRQRLDDSglpvdfwVLASdVPGVFNLGGDLALFAEliragdrdallayaRACVDGVH 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  80 AFrewHKTFELiqfgkvPVV--AAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMT 157
Cdd:PRK08788 113 AF---HRGFGA------GAIsiALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAE 183
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 158 DMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLpmtnYAVTHVLP--RIVDQSQQDGLM--TEALIAAV 233
Cdd:PRK08788 184 ELILSGKLYTAEELHDMGLVDVLVEDGQGEAAVRTFIRKSKRKL----NGWRAMLRarRRVNPLSLEELMdiTEIWVDAA 259
                        250       260
                 ....*....|....*....|....*...
gi 497896961 234 VS---SDIRTQDRLADFLDRKKDKIQTA 258
Cdd:PRK08788 260 LQleeKDLRTMERLVRAQNRRVGDLAAA 287
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
8-181 4.52e-15

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 72.18  E-value: 4.52e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   8 DVSVDGAVLMVGLNRPQKrNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREWH 85
Cdd:PRK05869  11 DGSQDAGLATLLLSRPPT-NALTRQVYREIVAAANELGrrDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARVRQ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  86 KTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRT 165
Cdd:PRK05869  90 QAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRF 169
                        170
                 ....*....|....*.
gi 497896961 166 LYAKESYERGVAQYLV 181
Cdd:PRK05869 170 FDAEEALALGLIDEMV 185
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
96-201 8.07e-15

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 73.74  E-value: 8.07e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  96 VPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLYAKESYERG 175
Cdd:PRK11730 103 VPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVG 182
                         90       100
                 ....*....|....*....|....*..
gi 497896961 176 VAQYLVPVGQALLKATELAHK-IAGNL 201
Cdd:PRK11730 183 AVDAVVAPEKLQEAALALLKQaIAGKL 209
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
20-190 7.63e-14

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 69.81  E-value: 7.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   20 LNRPQKRNAMSLEVMHELRDTFT--NIPDGIGAAVLYSTSQH-FCTGLDLSEIRDQSVIDNVQAFRE-WHKTFELI---- 91
Cdd:pfam16113   6 LNRPKALNALNLEMVRALLAALKawEDDPAVKLVVLKGAGERaFCAGGDVRALYEAAKAGGGEAGRDfFREEYRLNylia 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   92 QFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGiALMTDMMLTGRTLYAKES 171
Cdd:pfam16113  86 TYPK-PYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPG-ELGLYLALTGARLNGADA 163
                         170       180
                  ....*....|....*....|.
gi 497896961  172 YERGVAQYLVPVG--QALLKA 190
Cdd:pfam16113 164 LAAGLATHYVPSArlPALEEA 184
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
10-198 1.12e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 68.46  E-value: 1.12e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  10 SVDGAVLMVGLNRPqKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVIDN-VQAFREWHK 86
Cdd:PRK07938   7 TPEPGIAEVTVDYP-PVNALPSAGWFALADAITAAGAdpDTRVVVLRAEGRGFNAGVDIKELQATPGFTAlIDANRGCFA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  87 TFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGlyvGVGASVRFPRIAGIALMTDMMLTGRTL 166
Cdd:PRK07938  86 AFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRG---ALGAATHLQRLVPQHLMRALFFTAATI 162
                        170       180       190
                 ....*....|....*....|....*....|..
gi 497896961 167 YAKESYERGVAQYLVPVGQALLKATELAHKIA 198
Cdd:PRK07938 163 TAAELHHFGSVEEVVPRDQLDEAALEVARKIA 194
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-175 3.81e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 67.40  E-value: 3.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   1 MSGKNYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTN--IPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDN- 77
Cdd:PRK07827   2 TPVDTLVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAaaADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPYd 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  78 --VQAFREWHKTFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIAL 155
Cdd:PRK07827  82 aaVARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAA 161
                        170       180
                 ....*....|....*....|
gi 497896961 156 mTDMMLTGRTLYAKESYERG 175
Cdd:PRK07827 162 -ARYYLTGEKFGAAEAARIG 180
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
13-182 4.90e-13

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 67.90  E-value: 4.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  13 GAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLS-----EIRDQSVIDNVqaFREWH 85
Cdd:PLN02874  19 GRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEkdDSVELIIIKGAGRAFSAGGDLKmfydgRESDDSCLEVV--YRMYW 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  86 KTFELIQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGiALMTDMMLTGRT 165
Cdd:PLN02874  97 LCYHIHTYKK-TQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPG-HLGEYLALTGAR 174
                        170
                 ....*....|....*..
gi 497896961 166 LYAKESYERGVAQYLVP 182
Cdd:PLN02874 175 LNGKEMVACGLATHFVP 191
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
13-254 6.75e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 66.34  E-value: 6.75e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  13 GAVLMVGLNRPQKRNAMSLEVMHEL---RDTFTNIPDgIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFrewHKTFE 89
Cdd:PRK06072   8 EGYAIVTMSRPDKLNALNLEMRNEFiskLKQINADPK-IRVVIVTGEGRAFCVGADLSEFAPDFAIDLRETF---YPIIR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  90 LIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGiALMTDMMLTGRTLYAK 169
Cdd:PRK06072  84 EIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTG-QRFYEILVLGGEFTAE 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 170 ESYERGVAQYlvpVGQALLKATELAHKIAgNLPMTNY-AVTHVLPRIVDQSQQDGLMTEALIAAVVSSDIRTQDRLADFL 248
Cdd:PRK06072 163 EAERWGLLKI---SEDPLSDAEEMANRIS-NGPFQSYiAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISSFK 238

                 ....*.
gi 497896961 249 DRKKDK 254
Cdd:PRK06072 239 EKREPK 244
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
9-190 8.61e-13

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 67.15  E-value: 8.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEV---MHELRDTFTNIPDgIGAAVLYSTSQH-FCTGLDLSEIRDQSVIDNVQA---- 80
Cdd:PRK05617   7 AEVEGGVGVITLNRPKALNALSLEMiraIDAALDAWEDDDA-VAAVVIEGAGERgFCAGGDIRALYEAARAGDPLAadrf 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  81 FREWHKTFELI-QFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGiALMTDM 159
Cdd:PRK05617  86 FREEYRLNALIaRYPK-PYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPG-ALGTYL 163
                        170       180       190
                 ....*....|....*....|....*....|...
gi 497896961 160 MLTGRTLYAKESYERGVAQYLVPVGQ--ALLKA 190
Cdd:PRK05617 164 ALTGARISAADALYAGLADHFVPSADlpALLDA 196
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
11-198 1.51e-12

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 65.37  E-value: 1.51e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  11 VDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNI---PDgIGAAVLYSTSQHFCTGLDLSEIrdQSVIDNVQAFREWHKT 87
Cdd:PRK07110  11 VEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIaqdPR-YKVVILTGYPNYFATGGTQEGL--LSLQTGKGTFTEANLY 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  88 FELIQFgKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLY 167
Cdd:PRK07110  88 SLALNC-PIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYR 166
                        170       180       190
                 ....*....|....*....|....*....|.
gi 497896961 168 AKESYERGVAQYLVPVGQALLKATELAHKIA 198
Cdd:PRK07110 167 GAELKKRGVPFPVLPRAEVLEKALELARSLA 197
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
7-138 7.02e-12

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 63.55  E-value: 7.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAF----- 81
Cdd:PRK07112   6 IRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATIVVLEGLPEVFCFGADFSAIAEKPDAGRADLIdaepl 85
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 497896961  82 -REWHKtfelIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLY 138
Cdd:PRK07112  86 yDLWHR----LATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLI 139
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
96-203 1.46e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 62.74  E-value: 1.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  96 VPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEamrglyVGVGA-----SVRFPRIAGIALMTDMMLTGRTLYAKE 170
Cdd:PRK06143 101 VPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPE------VRVGIpsvihAALLPRLIGWARTRWLLLTGETIDAAQ 174
                         90       100       110
                 ....*....|....*....|....*....|...
gi 497896961 171 SYERGVAQYLVPVGQALLKATELAHKIAGNLPM 203
Cdd:PRK06143 175 ALAWGLVDRVVPLAELDAAVERLAASLAGCGPQ 207
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
20-179 3.20e-11

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 62.69  E-value: 3.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  20 LNRPQKRNAMSLEVMHELR---DTFTNIPDgIGAAVLYSTSQHFCTGLD---LSEIRDQSVIDNVQAFREWHKTFELIQF 93
Cdd:PLN02851  57 LNRPSSLNALTIPMVARLKrlyESWEENPD-IGFVLMKGSGRAFCSGADvvsLYHLINEGNVEECKLFFENLYKFVYLQG 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  94 GKV-PVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIaLMTDMMLTGRTLYAKESY 172
Cdd:PLN02851 136 TYLkPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGY-LGEYLALTGQKLNGVEMI 214

                 ....*..
gi 497896961 173 ERGVAQY 179
Cdd:PLN02851 215 ACGLATH 221
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
20-189 2.27e-10

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 60.08  E-value: 2.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  20 LNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREWHKTFE----LIQF 93
Cdd:PLN02157  52 LNRPPALNALTTHMGYRLQKLYKNWEEdpNIGFVMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIREFFSSLYsfiyLLGT 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  94 GKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGiALMTDMMLTGRTLYAKESYE 173
Cdd:PLN02157 132 YLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPG-RLGEYLGLTGLKLSGAEMLA 210
                        170       180
                 ....*....|....*....|.
gi 497896961 174 RGVAQYL-----VPVGQALLK 189
Cdd:PLN02157 211 CGLATHYirseeIPVMEEQLK 231
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
9-175 2.61e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 59.16  E-value: 2.61e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   9 VSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD-GIGAAVLYSTSQHFCTGLDLSEIR---DQSVIDNVQAFREW 84
Cdd:PRK08140   8 LAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEDdGARALLLTGAGRGFCAGQDLADRDvtpGGAMPDLGESIETF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  85 HK-TFELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTG 163
Cdd:PRK08140  88 YNpLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLG 167
                        170
                 ....*....|..
gi 497896961 164 RTLYAKESYERG 175
Cdd:PRK08140 168 EKLSAEQAEQWG 179
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-182 4.47e-10

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 59.35  E-value: 4.47e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   1 MSGKNYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSeirdqSVIDNV 78
Cdd:PLN02988   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEdpSVKLVILKGHGRAFCAGGDVA-----AVVRDI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  79 QAFR----------EWHKTFELIQFGKVPVvAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFP 148
Cdd:PLN02988  80 EQGNwrlganffsdEYMLNYVMATYSKAQV-SILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLS 158
                        170       180       190
                 ....*....|....*....|....*....|....
gi 497896961 149 RIAGIaLMTDMMLTGRTLYAKESYERGVAQYLVP 182
Cdd:PLN02988 159 RLPGF-FGEYVGLTGARLDGAEMLACGLATHFVP 191
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
7-137 5.90e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 58.15  E-value: 5.90e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   7 LDVSVDG-AVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFRE 83
Cdd:PRK07468   6 IRIAVDArGVATLTLNRPEKHNALSARMIAELTTAARRLAAdaAVRVVVLTGAGKSFCAGGDLGWMRAQMTADRATRIEE 85
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 497896961  84 WHKTFELIQ----FGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGL 137
Cdd:PRK07468  86 ARRLAMMLKalndLPK-PLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGL 142
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
20-137 2.18e-08

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 53.66  E-value: 2.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  20 LNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDQSVID---NVQAFREWHKTFELIQFG 94
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSdaSLRFLLLRGRGRHFSAGADLAWMQQSADLDyntNLDDARELAELMYNLYRL 100
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 497896961  95 KVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGL 137
Cdd:PRK05674 101 KIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGL 143
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
12-198 3.26e-08

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 53.10  E-value: 3.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  12 DGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQHFCTGLDLSEIRDqsVIDNVQA-FREWHKTF 88
Cdd:PRK07327  19 PPGVLEIVLNGPGALNAADARMHRELADIWRDVDRdpDVRVVLIRGEGKAFSAGGDLALVEE--MADDFEVrARVWREAR 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  89 EL----IQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGR 164
Cdd:PRK07327  97 DLvynvINCDK-PIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLLLCE 175
                        170       180       190
                 ....*....|....*....|....*....|....
gi 497896961 165 TLYAKESYERGVAQYLVPVGQALLKATELAHKIA 198
Cdd:PRK07327 176 PVSGEEAERIGLVSLAVDDDELLPKALEVAERLA 209
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
6-233 8.91e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 51.97  E-value: 8.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   6 YLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTF--TNIPDGIGAAVLYSTSQHFCTGLDLSEI-------------- 69
Cdd:PRK08272  11 TMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVerADLDPGVHVILVSGAGKGFCAGYDLSAYaegsssgggggayp 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  70 --------RDQSVIDNVQAFREWHKTFE----LIQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPeAMRGL 137
Cdd:PRK08272  91 gkrqavnhLPDDPWDPMIDYQMMSRFVRgfmsLWHAHK-PTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYP-PTRVW 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 138 yvGVGASVRFPRIAGIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAG----NLPMTNYAVTHVLp 213
Cdd:PRK08272 169 --GVPATGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAvpvnQLAMVKLAVNSAL- 245
                        250       260
                 ....*....|....*....|
gi 497896961 214 rivdqsQQDGLMTEALIAAV 233
Cdd:PRK08272 246 ------LQQGVATSQMLATV 259
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
15-196 3.77e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 49.79  E-value: 3.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  15 VLMVGLNRPQKRNAMSLEVMHELRDTFT--NIPDGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFREWHKTFELIQ 92
Cdd:PRK06023  16 VQVIRFNRPEKKNAITRAMYATMAKALKaaDADDAIRAHVFLGTEGCFSAGNDMQDFLAAAMGGTSFGSEILDFLIALAE 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  93 FGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRFPRIAGIALMTDMMLTGRTLYAKESY 172
Cdd:PRK06023  96 AEK-PIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAAQ 174
                        170       180
                 ....*....|....*....|....*...
gi 497896961 173 ERGVAQYLVPVG----QALLKATELAHK 196
Cdd:PRK06023 175 EAGLIWKIVDEEaveaETLKAAEELAAK 202
PLN02921 PLN02921
naphthoate synthase
2-185 1.27e-06

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 48.63  E-value: 1.27e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   2 SGKNYLDV----SVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDGIGAAVLYSTSQ---HFCTGLDLSeIRDQ-- 72
Cdd:PLN02921  60 SGKEFTDIiyekAVGEGIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKgtkAFCSGGDQA-VRGKdg 138
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  73 ----------SVIDNVQAFREWHKtfeliqfgkvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLY-VGV 141
Cdd:PLN02921 139 yvgpddagrlNVLDLQIQIRRLPK----------PVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFdAGY 208
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 497896961 142 GASVrFPRIAGIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQ 185
Cdd:PLN02921 209 GSSI-MARLVGQKKAREMWFLARFYTASEALKMGLVNTVVPLDE 251
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
4-128 3.93e-06

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 46.81  E-value: 3.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   4 KNYLDV---SVDGaVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVLYSTSQH-FCTGldlseiRDQSV--- 74
Cdd:PRK07396  10 KEYEDIlykSADG-IAKITINRPEVRNAFRPKTVKEMIDAFADARDddNIGVIILTGAGDKaFCSG------GDQKVrgy 82
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497896961  75 ---ID-------NVQAFRewhktfELIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFF 128
Cdd:PRK07396  83 ggyVDddgvprlNVLDLQ------RLIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIF 140
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
1-196 1.03e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 45.79  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   1 MSGKNYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIPDG-IGAAVLYSTSQHFCTGLDLSEIRDQsviDNVQ 79
Cdd:PRK07659   2 TSKMESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESsAHIVVLRGNGRGFSAGGDIKMMLSS---NDES 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  80 AFREWHKTFE-----LIQFGKVpVVAAITGAAIGGGLEIATACSLRVVDDSAFFslpeAMRGLYVGV----GASVRFPRI 150
Cdd:PRK07659  79 KFDGVMNTISeivvtLYTMPKL-TISAIHGPAAGLGLSIALTADYVIADISAKL----AMNFIGIGLipdgGGHFFLQKR 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 497896961 151 AGIALMTDMMLTGRTLYAKESYERGVAQYLV---PVGQALLKATELAHK 196
Cdd:PRK07659 154 VGENKAKQIIWEGKKLSATEALDLGLIDEVIggdFQTAAKQKISEWLQK 202
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
27-214 1.88e-05

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 44.87  E-value: 1.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  27 NAMSLEVMHELRDTFTNIP-DGIGAAVLYSTSQH---FCTGLDLSEIRDQSVidNVQAFREWHKT---FeLIQFGKVPV- 98
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALEnDPTVRGVVFASGLRrdvFTAGNDIAELYAPKT--SAARYAEFWLTqttF-LVRLLRSRLa 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  99 -VAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLYVGVGASVRF-PRIAGIALMTDMMLTGRTLYAKESYERGV 176
Cdd:PLN03214 110 tVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIPVPKFWARLFmGRVIDRKVAESLLLRGRLVRPAEAKQLGL 189
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 497896961 177 AQYLVPVGqALLKATELAHKIAGNLPMTNYAVTHVLPR 214
Cdd:PLN03214 190 IDEVVPAA-ALMEAAASAMERALKLPSAARAATKALLR 226
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
21-203 8.04e-05

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 42.88  E-value: 8.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  21 NRPQKRNAMSLEVMHELRDTFTNIPD--GIGAAVL------YSTSQHFCTGldlseiRDQSV------IDNVQAFR---- 82
Cdd:COG0447   34 NRPEVRNAFRPETVDELYDALDHAREdpDVGVVLLtgngpsKDGGWAFCSG------GDQRVrgrggyVYEDGVGRlnil 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  83 EWHKtfeLIQFGKVPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEAMRGLY-VGVGASVrFPRIAGIALMTDMML 161
Cdd:COG0447  108 EVQR---LIRFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFGQTGPDVGSFdAGYGSAY-LARQVGQKKAREIWF 183
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 497896961 162 TGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGNLPM 203
Cdd:COG0447  184 LCRQYSAQEALEMGLVNKVVPHAELEEEAVEWAREILEKSPT 225
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
5-192 1.09e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 42.42  E-value: 1.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961   5 NYLDVSVDGAVLMVGLNRPQKRNAMSLEVMHELRDTFTNIP--DGIGAAVLYSTSQHFCTGLDLSEIRDQSVIDNVQAFR 82
Cdd:PRK07260   2 EHIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEedPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  83 EWHK-----TFELIQFGKvPVVAAITGAAIGGGLEIATACSLRVVDDSAFFSlpEAmrglYVGVGASvrfPRIAGIALMT 157
Cdd:PRK07260  82 KIAElvneiSFAIKQLPK-PVIMCVDGAVAGAAANMAVAADFCIASTKTKFI--QA----FVGVGLA---PDAGGLFLLT 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 497896961 158 ---------DMMLTGRTLYAKESYERGVAqYLVPVGQALLKATE 192
Cdd:PRK07260 152 raiglnratHLAMTGEALTAEKALEYGFV-YRVAESEKLEKTCE 194
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
10-249 1.28e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 42.63  E-value: 1.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  10 SVDGAVLMVGLNRPQKRNAMSLEVMHELRDT--FTNIPDGIGAAVLYSTSQHFCTGLDLS---EIRDQSVIDNVQ----- 79
Cdd:PRK12478  10 TTAGPVATITLNRPEQLNTIVPPMPDEIEAAigLAERDQDIKVIVLRGAGRAFSGGYDFGggfQHWGEAMMTDGRwdpgk 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961  80 -----AFREWHKTFELIQFGKV--PVVAAITGAAIGGGLEIATACSLRVVDDSAFFSLPEA-MRGLYVgvgASVRFPRIa 151
Cdd:PRK12478  90 dfamvTARETGPTQKFMAIWRAskPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSrMWGAYL---TGMWLYRL- 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497896961 152 GIALMTDMMLTGRTLYAKESYERGVAQYLVPVGQALLKATELAHKIAGnLPMTNYAVTHVlprIVDQSQQD-GLMTEALI 230
Cdd:PRK12478 166 SLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEVATELAR-IPLSQLQAQKL---IVNQAYENmGLASTQTL 241
                        250
                 ....*....|....*....
gi 497896961 231 AAVVSSDIRTQDRLADFLD 249
Cdd:PRK12478 242 GGILDGLMRNTPDALEFIR 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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