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Conserved domains on  [gi|499226340|ref|WP_010923880|]
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MULTISPECIES: winged helix-turn-helix domain-containing protein [Sulfolobaceae]

Protein Classification

winged helix-turn-helix domain-containing protein( domain architecture ID 10633108)

winged helix-turn-helix domain-containing protein binds DNA, similar to Saccharolobus solfataricus Sso10a, a hyperthermophile coiled-coil DNA-binding protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_45 pfam14947
Winged helix-turn-helix; This winged helix-turn-helix domain contains an extended C-terminal ...
 4-79 2.60e-28

Winged helix-turn-helix; This winged helix-turn-helix domain contains an extended C-terminal alpha helix which is responsible for dimerization of this domain.


:

Pssm-ID: 405615 [Multi-domain]  Cd Length: 77  Bit Score: 97.29  E-value: 2.60e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499226340   4 KRSKLEIIQAILEACKSG-SPKTRIMYGANLSYALTGRYIKMLMDLEIIKQEGKQYMLTKKGEELLEDIRRFNDMRK 79
Cdd:pfam14947  1 RRSKLEIIADILEACSNGgAKKTKIMYNANLSYKLLNKYLDMLVDNGLIKNDGGKYVLTEKGLELLEKLREFRELAK 77
 
Name Accession Description Interval E-value
HTH_45 pfam14947
Winged helix-turn-helix; This winged helix-turn-helix domain contains an extended C-terminal ...
 4-79 2.60e-28

Winged helix-turn-helix; This winged helix-turn-helix domain contains an extended C-terminal alpha helix which is responsible for dimerization of this domain.


Pssm-ID: 405615 [Multi-domain]  Cd Length: 77  Bit Score: 97.29  E-value: 2.60e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499226340   4 KRSKLEIIQAILEACKSG-SPKTRIMYGANLSYALTGRYIKMLMDLEIIKQEGKQYMLTKKGEELLEDIRRFNDMRK 79
Cdd:pfam14947  1 RRSKLEIIADILEACSNGgAKKTKIMYNANLSYKLLNKYLDMLVDNGLIKNDGGKYVLTEKGLELLEKLREFRELAK 77
COG3432 COG3432
Predicted transcriptional regulator [Transcription];
3-79 3.89e-18

Predicted transcriptional regulator [Transcription];


Pssm-ID: 442658 [Multi-domain]  Cd Length: 83  Bit Score: 71.82  E-value: 3.89e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499226340  3 KKRSKLEIIQAILEACK-SGSPKTRIMYGANLSYALTGRYIKMLMDLEIIKQEG----KQYMLTKKGEELLEDIRRFNDM 77
Cdd:COG3432   2 KRRSRLEIIADILEALKnEGAKKTRIMYKANLSYDRLKKYLDLLEEKGLIEKEDdggrRIYRITEKGREFLEKYEEIKEL 81


                ..
gi 499226340 78 RK 79
Cdd:COG3432  82 LE 83
 
Name Accession Description Interval E-value
HTH_45 pfam14947
Winged helix-turn-helix; This winged helix-turn-helix domain contains an extended C-terminal ...
 4-79 2.60e-28

Winged helix-turn-helix; This winged helix-turn-helix domain contains an extended C-terminal alpha helix which is responsible for dimerization of this domain.


Pssm-ID: 405615 [Multi-domain]  Cd Length: 77  Bit Score: 97.29  E-value: 2.60e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499226340   4 KRSKLEIIQAILEACKSG-SPKTRIMYGANLSYALTGRYIKMLMDLEIIKQEGKQYMLTKKGEELLEDIRRFNDMRK 79
Cdd:pfam14947  1 RRSKLEIIADILEACSNGgAKKTKIMYNANLSYKLLNKYLDMLVDNGLIKNDGGKYVLTEKGLELLEKLREFRELAK 77
COG3432 COG3432
Predicted transcriptional regulator [Transcription];
3-79 3.89e-18

Predicted transcriptional regulator [Transcription];


Pssm-ID: 442658 [Multi-domain]  Cd Length: 83  Bit Score: 71.82  E-value: 3.89e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499226340  3 KKRSKLEIIQAILEACK-SGSPKTRIMYGANLSYALTGRYIKMLMDLEIIKQEG----KQYMLTKKGEELLEDIRRFNDM 77
Cdd:COG3432   2 KRRSRLEIIADILEALKnEGAKKTRIMYKANLSYDRLKKYLDLLEEKGLIEKEDdggrRIYRITEKGREFLEKYEEIKEL 81


                ..
gi 499226340 78 RK 79
Cdd:COG3432  82 LE 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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