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Conserved domains on  [gi|503164099|ref|WP_013398760|]
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MULTISPECIES: regulatory protein RecX [Rothia]

Protein Classification

regulatory protein RecX( domain architecture ID 10005398)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
195-351 1.35e-40

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 140.31  E-value: 1.35e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 195 EPDPYTRAKTLVYNQLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRGKHKKLSRTALRRE 274
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503164099 275 LKERGITGELAEDALAARTDEDEHRDAAELVRKKLRPsmnfSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEIE 351
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKKFGS----LKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLE 153
 
Name Accession Description Interval E-value
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
195-351 1.35e-40

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 140.31  E-value: 1.35e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 195 EPDPYTRAKTLVYNQLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRGKHKKLSRTALRRE 274
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503164099 275 LKERGITGELAEDALAARTDEDEHRDAAELVRKKLRPsmnfSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEIE 351
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKKFGS----LKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLE 153
recX PRK00117
recombination regulator RecX; Reviewed
191-351 3.20e-30

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 113.06  E-value: 3.20e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 191 KQREEPDPYTRAKTLVYNQLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRgKHKKLSRTA 270
Cdd:PRK00117   2 EDTARRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSR-ARKGYGPRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 271 LRRELKERGITGELAEDALAARtDEDEHRDAAELVRKKLRpsmnfSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEI 350
Cdd:PRK00117  81 IRQELRQKGVDREIIEEALAEL-DIDWEELARELARKKFR-----RPLPDDAKEKAKLVRFLARRGFSMDVIQRVLRNAL 154

                 .
gi 503164099 351 E 351
Cdd:PRK00117 155 D 155
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
224-351 7.19e-26

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 100.35  E-value: 7.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099  224 LADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRGKHKKLSRTALRRELKERGITGELAEDALAARTDEDEhrDAAE 303
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQ--IARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 503164099  304 LVRKKLRPsmnfSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEIE 351
Cdd:pfam02631  79 LAEKKFKR----YPAESDRKLKQKLIRFLARRGFSSEVIRAALQEEDE 122
 
Name Accession Description Interval E-value
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
195-351 1.35e-40

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 140.31  E-value: 1.35e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 195 EPDPYTRAKTLVYNQLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRGKHKKLSRTALRRE 274
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503164099 275 LKERGITGELAEDALAARTDEDEHRDAAELVRKKLRPsmnfSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEIE 351
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKKFGS----LKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLE 153
recX PRK00117
recombination regulator RecX; Reviewed
191-351 3.20e-30

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 113.06  E-value: 3.20e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 191 KQREEPDPYTRAKTLVYNQLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRgKHKKLSRTA 270
Cdd:PRK00117   2 EDTARRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSR-ARKGYGPRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 271 LRRELKERGITGELAEDALAARtDEDEHRDAAELVRKKLRpsmnfSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEI 350
Cdd:PRK00117  81 IRQELRQKGVDREIIEEALAEL-DIDWEELARELARKKFR-----RPLPDDAKEKAKLVRFLARRGFSMDVIQRVLRNAL 154

                 .
gi 503164099 351 E 351
Cdd:PRK00117 155 D 155
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
224-351 7.19e-26

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 100.35  E-value: 7.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099  224 LADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRGKHKKLSRTALRRELKERGITGELAEDALAARTDEDEhrDAAE 303
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQ--IARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 503164099  304 LVRKKLRPsmnfSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEIE 351
Cdd:pfam02631  79 LAEKKFKR----YPAESDRKLKQKLIRFLARRGFSSEVIRAALQEEDE 122
recX PRK14135
recombination regulator RecX; Provisional
197-360 2.23e-15

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 75.25  E-value: 2.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 197 DPYTRAKTLVYNQLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQrgkHKKLSR---TALRR 273
Cdd:PRK14135  54 DQVSKGKNLALYYLSYQMRTEKEVRDYLKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRT---NINTGDkgpRVIKQ 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 274 ELKERGITGELAEDALAARTDEDEHRDAAELVRKKLRPSMNFSDRTENEKILRrlvgMLARRGYSSSVAfSVVKEEIEry 353
Cdd:PRK14135 131 KLLQKGIEDEIIEEALSEYTEEDQIEVAQKLAEKLLKKYQKLPFKALKQKIIQ----SLLTKGFSYEVI-KAALEELD-- 203

                 ....*..
gi 503164099 354 rSEQEED 360
Cdd:PRK14135 204 -LEQDEE 209
recX PRK14134
recombination regulator RecX; Provisional
195-359 2.18e-10

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 60.59  E-value: 2.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 195 EPDPYTRAKTLVYNQLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQrgKHKKLSRTALRRE 274
Cdd:PRK14134  56 KEDNYIKCKGYALKYIEKSYKTEKQIKEKLYLKEYDEDAVNRVIRFLKEYNFIDDDKYCDMYIRE--KINSYGRNKIKYT 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 275 LKERGITGELAEDALAARTDEDEHRDAAELVRKKLRpSMNFSDrTENEKILRRLVGMLARRGYSSSVAFSVVKEEIERYR 354
Cdd:PRK14134 134 LLNKGIKENIIIEKINNIDEEKEKKVAYKLAEKKYK-ILILSE-KNKFKIYKKLGPYLISRGYSSNIAEWILNELIKNEA 211

                 ....*
gi 503164099 355 SEQEE 359
Cdd:PRK14134 212 LYKDN 216
recX PRK14137
recombination regulator RecX; Provisional
210-351 3.79e-07

recombination regulator RecX; Provisional


Pssm-ID: 172626  Cd Length: 195  Bit Score: 49.98  E-value: 3.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 210 LAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSFVEQRGkhkkLSRTALRRELKERGITGELAEDAL 289
Cdd:PRK14137  50 LAARAMTAAELRAKLERRSEDEALVTEVLERVQELGYQDDAQVARAENSRRG----VGALRVRQTLRRRGVEETLIEETL 125
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503164099 290 AARTDEDEHRDAAELVRKKlrpsmnFSDRTENEKILRRLVGMLARRGYSSSVAFSVVKEEIE 351
Cdd:PRK14137 126 AARDPQEEQQEARNLLERR------WSSFARKRDPRASAYAFLARRGFSGAVIWPAIREVAA 181
recX PRK14136
recombination regulator RecX; Provisional
98-347 2.49e-04

recombination regulator RecX; Provisional


Pssm-ID: 237620 [Multi-domain]  Cd Length: 309  Bit Score: 42.30  E-value: 2.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099  98 SGARKKRRNPDWKKGFRRPKNTEKSPFAPAIGAHRAE-EEHPekvRKKKRSSGPLFREGSALNEPlsteeealirgiaae 176
Cdd:PRK14136  85 VGVRDAGAPGGRAADARAANLSSAAKRAEAAGDVYTRtSQHP---RRTRRAAGPFHSDSSPSASS--------------- 146
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 177 ektnvpGTNRSGRWKQREEPDPYTRAKTLVYnqLAYSAKSRAQLQKKLADKGFEESLIEPLLDKFEAAHLIDDAEYARSF 256
Cdd:PRK14136 147 ------EDDGAARSRASSRPARSLKGRALGY--LSRREYSRAELARKLAPYADESDSVEPLLDALEREGWLSDARFAESL 218
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503164099 257 VeqrgkHKKLSRTALRR---ELKERGITGELAEdALAARTDEDEHRDAAELVRKKlrpsmnFSDRTENEKILRRLVGMLA 333
Cdd:PRK14136 219 V-----HRRASRVGSARivsELKRHAVGDALVE-SVGAQLRETEFERAQAVWRKK------FGALPQTPAERAKQARFLA 286
                        250
                 ....*....|....
gi 503164099 334 RRGYSSSVAFSVVK 347
Cdd:PRK14136 287 ARGFSSATIVKLLK 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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