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Conserved domains on  [gi|520845815|ref|WP_020303575|]
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MULTISPECIES: dephospho-CoA kinase [Hafnia]

Protein Classification

dephospho-CoA kinase( domain architecture ID 11415511)

dephospho-CoA kinase catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis

CATH:  3.40.50.300
EC:  2.7.1.24
Gene Ontology:  GO:0004140|GO:0005524|GO:0015937|GO:0016310

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 2-193 1.29e-84

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


:

Pssm-ID: 440007  Cd Length: 193  Bit Score: 248.44  E-value: 1.29e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   2 TYIVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEK 81
Cdd:COG0237    1 MLIIGLTGGIGSGKSTVARMFAELGAPVIDADAIARELVEPGGPALAAIVEAFGEEILDADGSLDRKALAEIVFADPEAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  82 QWLDGLLHPLIHLETQRLLAAIV-APYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQA 160
Cdd:COG0237   81 KKLEAIVHPLVREEIERRLAAARgAPYVVLDIPLLFETGLEKLVDRVIVVDAPEEVQIERLMARDGLSEEEAEARIAAQM 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 520845815 161 TRAQRLACADDIIENSGSPETIAPRVASLHRHY 193
Cdd:COG0237  161 PDEEKRARADFVIDNDGSLEELRAQVDALLEKL 193
 
Name Accession Description Interval E-value
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 2-193 1.29e-84

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 248.44  E-value: 1.29e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   2 TYIVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEK 81
Cdd:COG0237    1 MLIIGLTGGIGSGKSTVARMFAELGAPVIDADAIARELVEPGGPALAAIVEAFGEEILDADGSLDRKALAEIVFADPEAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  82 QWLDGLLHPLIHLETQRLLAAIV-APYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQA 160
Cdd:COG0237   81 KKLEAIVHPLVREEIERRLAAARgAPYVVLDIPLLFETGLEKLVDRVIVVDAPEEVQIERLMARDGLSEEEAEARIAAQM 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 520845815 161 TRAQRLACADDIIENSGSPETIAPRVASLHRHY 193
Cdd:COG0237  161 PDEEKRARADFVIDNDGSLEELRAQVDALLEKL 193
DPCK cd02022
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of ...
 4-180 8.66e-76

Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.


Pssm-ID: 238980  Cd Length: 179  Bit Score: 225.86  E-value: 8.66e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   4 IVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQW 83
Cdd:cd02022    1 IIGLTGGIGSGKSTVAKLLKELGIPVIDADKIAHEVYEPGGPALQAIVEAFGPDILLEDGELDRKKLGEIVFADPEKRKK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  84 LDGLLHPLIHLETQRLLAAIVA-PYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQATR 162
Cdd:cd02022   81 LEAITHPLIRKEIEEQLAEARKeKVVVLDIPLLFETGLEKLVDRVIVVDAPPEIQIERLMKRDGLSEEEAEARIASQMPL 160

                        170
                 ....*....|....*...
gi 520845815 163 AQRLACADDIIENSGSPE 180
Cdd:cd02022  161 EEKRARADFVIDNSGSLE 178
CoaE pfam01121
Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of ...
 3-178 9.16e-76

Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form Coenzyme A EC:2.7.1.24. This enzyme uses ATP in its reaction.


Pssm-ID: 426062  Cd Length: 180  Bit Score: 225.66  E-value: 9.16e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815    3 YIVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQ 82
Cdd:pfam01121   1 LIVGLTGGIGSGKSTVANYFRDLGVPIIDADAIARQVVEPGGPALSRIVRHFGPTILDADGQLDRRALRELVFSNPERKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   83 WLDGLLHPLIHLETQRLLAAIVA-PYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQAT 161
Cdd:pfam01121  81 WLNGILHPLIRREIFKQIATLTAaPYVVLDIPLLFESGLHKLCHRVLVVDAPPELQVERLVARDGLSREEAQARIAAQAS 160

                         170
                  ....*....|....*..
gi 520845815  162 RAQRLACADDIIENSGS 178
Cdd:pfam01121 161 REERLALADDVLDNDGS 177
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 4-191 7.04e-61

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 188.37  E-value: 7.04e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815    4 IVALTGGIGSGKSTVAEAF-NQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQ 82
Cdd:TIGR00152   1 LIALTGGIGSGKSTVLQYLaDKYHFPVIDADKIAHQVVEPGQPAYHAIADHFGANILNQDGELDRKALGNYVFNDPEELK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   83 WLDGLLHPLIHLETQRLLAAIVAPYAL--WVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQA 160
Cdd:TIGR00152  81 WLNALTHPLIRQWMKKLIAQFQSKYALvlLDVPLLFENNLRSLVDYVIVVERSPELQLERLMQRNDLTEEEVKKRLASQM 160

                         170       180       190
                  ....*....|....*....|....*....|.
gi 520845815  161 TRAQRLACADDIIENSGsPETIAPRVASLHR 191
Cdd:TIGR00152 161 DIEEKLARIDTVIDNSG-PATLADLVKQLEE 190
coaE PRK03333
dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional
 5-194 8.81e-44

dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional


Pssm-ID: 179560 [Multi-domain]  Cd Length: 395  Bit Score: 150.54  E-value: 8.81e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   5 VALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQWL 84
Cdd:PRK03333   4 IGLTGGIGAGKSTVAARLAELGAVVVDADVLAREVVEPGTEGLAALVAAFGDDILLADGALDRPALAAKAFADDEARAVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  85 DGLLHPLIHLETQRLLAAiVAPYALWV--VPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQATR 162
Cdd:PRK03333  84 NGIVHPLVGARRAELIAA-APEDAVVVedIPLLVESGMAPLFHLVVVVDADVEVRVRRLVEQRGMAEADARARIAAQASD 162

                        170       180       190
                 ....*....|....*....|....*....|..
gi 520845815 163 AQRLACADDIIENSGSPETIAPRVASLHRHYL 194
Cdd:PRK03333 163 EQRRAVADVWLDNSGTPDELVEAVRALWADRL 194
 
Name Accession Description Interval E-value
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 2-193 1.29e-84

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 248.44  E-value: 1.29e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   2 TYIVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEK 81
Cdd:COG0237    1 MLIIGLTGGIGSGKSTVARMFAELGAPVIDADAIARELVEPGGPALAAIVEAFGEEILDADGSLDRKALAEIVFADPEAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  82 QWLDGLLHPLIHLETQRLLAAIV-APYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQA 160
Cdd:COG0237   81 KKLEAIVHPLVREEIERRLAAARgAPYVVLDIPLLFETGLEKLVDRVIVVDAPEEVQIERLMARDGLSEEEAEARIAAQM 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 520845815 161 TRAQRLACADDIIENSGSPETIAPRVASLHRHY 193
Cdd:COG0237  161 PDEEKRARADFVIDNDGSLEELRAQVDALLEKL 193
DPCK cd02022
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of ...
 4-180 8.66e-76

Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.


Pssm-ID: 238980  Cd Length: 179  Bit Score: 225.86  E-value: 8.66e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   4 IVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQW 83
Cdd:cd02022    1 IIGLTGGIGSGKSTVAKLLKELGIPVIDADKIAHEVYEPGGPALQAIVEAFGPDILLEDGELDRKKLGEIVFADPEKRKK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  84 LDGLLHPLIHLETQRLLAAIVA-PYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQATR 162
Cdd:cd02022   81 LEAITHPLIRKEIEEQLAEARKeKVVVLDIPLLFETGLEKLVDRVIVVDAPPEIQIERLMKRDGLSEEEAEARIASQMPL 160

                        170
                 ....*....|....*...
gi 520845815 163 AQRLACADDIIENSGSPE 180
Cdd:cd02022  161 EEKRARADFVIDNSGSLE 178
CoaE pfam01121
Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of ...
 3-178 9.16e-76

Dephospho-CoA kinase; This family catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form Coenzyme A EC:2.7.1.24. This enzyme uses ATP in its reaction.


Pssm-ID: 426062  Cd Length: 180  Bit Score: 225.66  E-value: 9.16e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815    3 YIVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQ 82
Cdd:pfam01121   1 LIVGLTGGIGSGKSTVANYFRDLGVPIIDADAIARQVVEPGGPALSRIVRHFGPTILDADGQLDRRALRELVFSNPERKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   83 WLDGLLHPLIHLETQRLLAAIVA-PYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQAT 161
Cdd:pfam01121  81 WLNGILHPLIRREIFKQIATLTAaPYVVLDIPLLFESGLHKLCHRVLVVDAPPELQVERLVARDGLSREEAQARIAAQAS 160

                         170
                  ....*....|....*..
gi 520845815  162 RAQRLACADDIIENSGS 178
Cdd:pfam01121 161 REERLALADDVLDNDGS 177
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 4-191 7.04e-61

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 188.37  E-value: 7.04e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815    4 IVALTGGIGSGKSTVAEAF-NQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQ 82
Cdd:TIGR00152   1 LIALTGGIGSGKSTVLQYLaDKYHFPVIDADKIAHQVVEPGQPAYHAIADHFGANILNQDGELDRKALGNYVFNDPEELK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   83 WLDGLLHPLIHLETQRLLAAIVAPYAL--WVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQA 160
Cdd:TIGR00152  81 WLNALTHPLIRQWMKKLIAQFQSKYALvlLDVPLLFENNLRSLVDYVIVVERSPELQLERLMQRNDLTEEEVKKRLASQM 160

                         170       180       190
                  ....*....|....*....|....*....|.
gi 520845815  161 TRAQRLACADDIIENSGsPETIAPRVASLHR 191
Cdd:TIGR00152 161 DIEEKLARIDTVIDNSG-PATLADLVKQLEE 190
coaE PRK03333
dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional
 5-194 8.81e-44

dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional


Pssm-ID: 179560 [Multi-domain]  Cd Length: 395  Bit Score: 150.54  E-value: 8.81e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   5 VALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQWL 84
Cdd:PRK03333   4 IGLTGGIGAGKSTVAARLAELGAVVVDADVLAREVVEPGTEGLAALVAAFGDDILLADGALDRPALAAKAFADDEARAVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  85 DGLLHPLIHLETQRLLAAiVAPYALWV--VPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQATR 162
Cdd:PRK03333  84 NGIVHPLVGARRAELIAA-APEDAVVVedIPLLVESGMAPLFHLVVVVDADVEVRVRRLVEQRGMAEADARARIAAQASD 162

                        170       180       190
                 ....*....|....*....|....*....|..
gi 520845815 163 AQRLACADDIIENSGSPETIAPRVASLHRHYL 194
Cdd:PRK03333 163 EQRRAVADVWLDNSGTPDELVEAVRALWADRL 194
PLN02422 PLN02422
dephospho-CoA kinase
 4-180 1.86e-40

dephospho-CoA kinase


Pssm-ID: 215232  Cd Length: 232  Bit Score: 137.57  E-value: 1.86e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   4 IVALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQW 83
Cdd:PLN02422   3 VVGLTGGIASGKSTVSNLFKSSGIPVVDADKVARDVLKKGSGGWKRVVAAFGEDILLPDGEVDREKLGQIVFSDPSKRQL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  84 LDGLLHPLIHLETQRLLAaivapyALWV---------VPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAEN 154
Cdd:PLN02422  83 LNRLLAPYISSGIFWEIL------KLWLkgckvivldIPLLFETKMDKWTKPVVVVWVDPETQLERLMARDGLSEEQARN 156

                        170       180
                 ....*....|....*....|....*.
gi 520845815 155 ILAAQATRAQRLACADDIIENSGSPE 180
Cdd:PLN02422 157 RINAQMPLDWKRSKADIVIDNSGSLE 182
coaE PRK14734
dephospho-CoA kinase; Provisional
 5-189 2.68e-39

dephospho-CoA kinase; Provisional


Pssm-ID: 237808  Cd Length: 200  Bit Score: 133.43  E-value: 2.68e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   5 VALTGGIGSGKSTVAEAFNQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQWL 84
Cdd:PRK14734   4 IGLTGGIGSGKSTVADLLSSEGFLIVDADQVARDIVEPGQPALAELAEAFGDDILNPDGTLDRAGLAAKAFASPEQTALL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  85 DGLLHPLIHLETQRLLA---AIVAPYALWVVPLLVENGLSKRAHRVLVVDVDPDVQLQRTMARDGISREQAENILAAQAT 161
Cdd:PRK14734  84 NAITHPRIAEETARRFNearAQGAKVAVYDMPLLVEKGLDRKMDLVVVVDVDVEERVRRLVEKRGLDEDDARRRIAAQIP 163

                        170       180
                 ....*....|....*....|....*...
gi 520845815 162 RAQRLACADDIIENSGSPETIAPRVASL 189
Cdd:PRK14734 164 DDVRLKAADIVVDNNGTREQLLAQVDGL 191
PTZ00451 PTZ00451
dephospho-CoA kinase; Provisional
 4-176 3.09e-18

dephospho-CoA kinase; Provisional


Pssm-ID: 185630  Cd Length: 244  Bit Score: 79.92  E-value: 3.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815   4 IVALTGGIGSGKSTVAEAF-NQLGVPVVDADIIARQVVAIGAPALQKIAEHFGPEILQNDGALNRAALREVIFNQPQEKQ 82
Cdd:PTZ00451   3 LIGLTGGIACGKSTVSRILrEEHHIEVIDADLVVRELQAPNMACTRKIAARWPLCVHPETGELNRAELGKIIFSDAQARR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520845815  83 WLDGLLHPLIHLETQRLLAAI---------VAPYALWVV---PLLVE-NGLSKRAHRVLVVDVDPDVQLQRTMARDGISR 149
Cdd:PTZ00451  83 ALGRIMNPPIFRAILKRIAAAwwedlwrsgAGSSPLIVVldaPTLFEtKTFTYFVSASVVVSCSEERQIERLRKRNGFSK 162

                        170       180
                 ....*....|....*....|....*..
gi 520845815 150 EQAENILAAQATRAQRLACADDIIENS 176
Cdd:PTZ00451 163 EEALQRIGSQMPLEEKRRLADYIIEND 189
NK cd02019
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 4-35 3.53e-03

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


Pssm-ID: 238977 [Multi-domain]  Cd Length: 69  Bit Score: 35.00  E-value: 3.53e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 520845815   4 IVALTGGIGSGKSTVA----EAFNQLGVPVVDADII 35
Cdd:cd02019    1 IIAITGGSGSGKSTVAkklaEQLGGRSVVVLDEIVI 36
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 5-74 3.80e-03

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 36.65  E-value: 3.80e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 520845815   5 VALTGGIGSGKSTVAEAF-NQLGVPVVDADiiarqvvaigapalQKIAEHFG---PEILQNDG-----ALNRAALREVI 74
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLaKRLGLPFVDTD--------------AEIEERAGmsiPEIFAEEGeagfrELEREVLAELL 65
COG3911 COG3911
Predicted ATPase [General function prediction only];
5-47 4.04e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443117  Cd Length: 180  Bit Score: 36.72  E-value: 4.04e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 520845815   5 VALTGGIGSGKSTVAEAFNQLGVPVVDA---DIIARQvVAIGAPAL 47
Cdd:COG3911    6 IVITGGPGSGKTTLLNALARRGYACVPEagrEIIREQ-QAIGGDAL 50
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 4-63 5.66e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 35.99  E-value: 5.66e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 520845815   4 IVALTGGIGSGKSTVAEAF-NQLGVPVVDADiiarqvvaigapalQKIAEHFG---PEILQNDG 63
Cdd:cd00464    1 NIVLIGMMGAGKTTVGRLLaKALGLPFVDLD--------------ELIEQRAGmsiPEIFAEEG 50
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
4-45 5.96e-03

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 36.08  E-value: 5.96e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 520845815   4 IVALTGGIGSGKSTVAEAFNQLGVPVVD-ADIIARQVVAIGAP 45
Cdd:PRK01184   3 IIGVVGMPGSGKGEFSKIAREMGIPVVVmGDVIREEVKKRGLE 45
COG4185 COG4185
Predicted ABC-type ATPase or kinase [General function prediction only];
3-38 8.09e-03

Predicted ABC-type ATPase or kinase [General function prediction only];


Pssm-ID: 443339  Cd Length: 197  Bit Score: 36.02  E-value: 8.09e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 520845815   3 YIVAltGGIGSGKSTVAEAFNQ---LGVPVVDADIIARQ 38
Cdd:COG4185    7 YIIA--GPNGAGKSTFARTILPeelGGLEFVNADLIARG 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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