View
Concise Results
Standard Results
Full Results
MULTISPECIES: dihydroxy-acid dehydratase [Vibrio]
Protein Classification
dihydroxy-acid dehydratase ( domain architecture ID 10013972 )
dihydroxy-acid dehydratase catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
List of domain hits
Name
Accession
Description
Interval
E-value
PRK12448
PRK12448 dihydroxy-acid dehydratase; Provisional
2-613
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237104
Cd Length: 615
Bit Score: 1404.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 2 PKYRS A TTTHGRNMAGARALWRATG V KDEDFGKPIIAVVNSFTQFVPGHVHLKD M GQLVA G EIE K AGG I AKEFNTIAVDD 81
Cdd:PRK12448 1 PKYRS R TTTHGRNMAGARALWRATG M KDEDFGKPIIAVVNSFTQFVPGHVHLKD L GQLVA R EIE A AGG V AKEFNTIAVDD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 82 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM M MAA M RLNIPV I FVSGGPMEAGKTKLSD Q IIK 161
Cdd:PRK12448 81 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM L MAA L RLNIPV V FVSGGPMEAGKTKLSD K IIK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 162 LDLVDAM IQG ADP T VSD QQSE Q V ERSACPTCGSCSGMFTANSMNCLTEALGLS Q PGNGS M LATHADR E QLF IN AG K RIV D 241
Cdd:PRK12448 161 LDLVDAM VAA ADP S VSD EDVA Q I ERSACPTCGSCSGMFTANSMNCLTEALGLS L PGNGS L LATHADR K QLF LE AG R RIV E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 242 L TR RYYEQDDES A LPR N IA NRD AFENAM A LDIAMGGS S NTVLHLLAAAQE G E I DF D M N DID EM SR R VP H LCKVAP S TQKY 321
Cdd:PRK12448 241 L AK RYYEQDDES V LPR S IA TKA AFENAM T LDIAMGGS T NTVLHLLAAAQE A E V DF T M A DID RL SR K VP C LCKVAP N TQKY 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 322 HMEDVHRAGG V M A ILGELDRAGLL NGSTS TV L G M T MQQQ L AEY DIM Q T EN E E V LK FFRA G P A GIRTT Q AFSQDCRWD R LD 401
Cdd:PRK12448 321 HMEDVHRAGG I M G ILGELDRAGLL HTDVP TV H G L T LGEA L DQW DIM R T QD E A V KE FFRA A P G GIRTT V AFSQDCRWD S LD 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 402 D DRENGCIRS K E N A F S QE GGLAVL S GNIA V DGCIVKTAGVDE EN LKF Q GPA I VFESQD S AV DG ILGGKVKAG E VVVIRYE 481
Cdd:PRK12448 401 T DRENGCIRS V E H A Y S KD GGLAVL Y GNIA E DGCIVKTAGVDE SI LKF T GPA R VFESQD D AV EA ILGGKVKAG D VVVIRYE 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 482 GPKGGPGMQEMLYPT T YLKS M GLGK S CAL L TDGRFSGGTSGLSIGH A SPEAASGG T IGLV Q DGDII T IDIP S RSI T L D V A 561
Cdd:PRK12448 481 GPKGGPGMQEMLYPT S YLKS K GLGK A CAL I TDGRFSGGTSGLSIGH V SPEAASGG A IGLV E DGDII E IDIP N RSI N L L V S 560
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 520914136 562 ED ELAARRA K Q DEL G --- WKP VD R Q R E VSFALKAYA SM ATSADKGAVRDKSKL E G 613
Cdd:PRK12448 561 DE ELAARRA A Q EAR G dka WKP KN R E R K VSFALKAYA AL ATSADKGAVRDKSKL G G 615
Name
Accession
Description
Interval
E-value
PRK12448
PRK12448 dihydroxy-acid dehydratase; Provisional
2-613
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237104
Cd Length: 615
Bit Score: 1404.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 2 PKYRS A TTTHGRNMAGARALWRATG V KDEDFGKPIIAVVNSFTQFVPGHVHLKD M GQLVA G EIE K AGG I AKEFNTIAVDD 81
Cdd:PRK12448 1 PKYRS R TTTHGRNMAGARALWRATG M KDEDFGKPIIAVVNSFTQFVPGHVHLKD L GQLVA R EIE A AGG V AKEFNTIAVDD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 82 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM M MAA M RLNIPV I FVSGGPMEAGKTKLSD Q IIK 161
Cdd:PRK12448 81 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM L MAA L RLNIPV V FVSGGPMEAGKTKLSD K IIK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 162 LDLVDAM IQG ADP T VSD QQSE Q V ERSACPTCGSCSGMFTANSMNCLTEALGLS Q PGNGS M LATHADR E QLF IN AG K RIV D 241
Cdd:PRK12448 161 LDLVDAM VAA ADP S VSD EDVA Q I ERSACPTCGSCSGMFTANSMNCLTEALGLS L PGNGS L LATHADR K QLF LE AG R RIV E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 242 L TR RYYEQDDES A LPR N IA NRD AFENAM A LDIAMGGS S NTVLHLLAAAQE G E I DF D M N DID EM SR R VP H LCKVAP S TQKY 321
Cdd:PRK12448 241 L AK RYYEQDDES V LPR S IA TKA AFENAM T LDIAMGGS T NTVLHLLAAAQE A E V DF T M A DID RL SR K VP C LCKVAP N TQKY 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 322 HMEDVHRAGG V M A ILGELDRAGLL NGSTS TV L G M T MQQQ L AEY DIM Q T EN E E V LK FFRA G P A GIRTT Q AFSQDCRWD R LD 401
Cdd:PRK12448 321 HMEDVHRAGG I M G ILGELDRAGLL HTDVP TV H G L T LGEA L DQW DIM R T QD E A V KE FFRA A P G GIRTT V AFSQDCRWD S LD 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 402 D DRENGCIRS K E N A F S QE GGLAVL S GNIA V DGCIVKTAGVDE EN LKF Q GPA I VFESQD S AV DG ILGGKVKAG E VVVIRYE 481
Cdd:PRK12448 401 T DRENGCIRS V E H A Y S KD GGLAVL Y GNIA E DGCIVKTAGVDE SI LKF T GPA R VFESQD D AV EA ILGGKVKAG D VVVIRYE 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 482 GPKGGPGMQEMLYPT T YLKS M GLGK S CAL L TDGRFSGGTSGLSIGH A SPEAASGG T IGLV Q DGDII T IDIP S RSI T L D V A 561
Cdd:PRK12448 481 GPKGGPGMQEMLYPT S YLKS K GLGK A CAL I TDGRFSGGTSGLSIGH V SPEAASGG A IGLV E DGDII E IDIP N RSI N L L V S 560
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 520914136 562 ED ELAARRA K Q DEL G --- WKP VD R Q R E VSFALKAYA SM ATSADKGAVRDKSKL E G 613
Cdd:PRK12448 561 DE ELAARRA A Q EAR G dka WKP KN R E R K VSFALKAYA AL ATSADKGAVRDKSKL G G 615
IlvD
COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, ...
1-609
0e+00
Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; Dihydroxyacid dehydratase/phosphogluconate dehydratase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439899
Cd Length: 558
Bit Score: 1020.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 1 MPK Y RS A T T T H GR NM A G ARAL W RATG VK DEDFGKPII AVV NS FTQF VPGHVHL K D MGQL V AGE I EK AGG IAK EFNTIAV D 80
Cdd:COG0129 1 MPK M RS D T V T K GR ER A P ARAL L RATG LT DEDFGKPII GIA NS WNEI VPGHVHL D D LAEA V KEG I RA AGG VPF EFNTIAV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 81 DGIAMGH G GM L YSLPSRELIADS V E Y MVNAHC A D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA GK TK l SDQII 160
Cdd:COG0129 81 DGIAMGH E GM R YSLPSRELIADS I E T MVNAHC F D GL VCI PG CDKITPGM L MAA A RLNIP S IFV Y GGPM LP GK YD - GKDLD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 161 KL D LVD A MIQG A DPTV SD QQSEQV ER S ACP T CGSCSGMFTAN S M N CLTEALGLS Q PG N G SML A TH A D R EQ L FIN AG K RIV 240
Cdd:COG0129 160 IV D VFE A VGAY A AGKI SD EELKEI ER N ACP G CGSCSGMFTAN T M A CLTEALGLS L PG S G TIP A VS A E R RR L ARE AG R RIV 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 241 D L TRR yyeqdde SAL PR N I AN R D AFENA M A L D I A M GGS S NTVLHLLA A A Q E GEI D FDMN D I D EM SRR V PHLC KVA PS T q K 320
Cdd:COG0129 240 E L VEK ------- DIK PR D I LT R E AFENA I A V D M A L GGS T NTVLHLLA I A H E AGV D LTLD D F D RI SRR T PHLC DLK PS G - K 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 321 YHMED V HRAGG VM A ILG EL DR AGLL N G STS TV L G M T MQQQ LA EY DI mqteneevlkffragpagirttqafsqdcrwdrl 400
Cdd:COG0129 312 YHMED L HRAGG IP A VMK EL LD AGLL H G DCL TV T G K T LAEN LA DA DI ---------------------------------- 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 401 dd DR ENGC IR SKE N AF S QE GGLA V L S GN I A V DG CI VKTAGVDE EN L K F Q GPA I VF E S QDS AV DG ILGGK V KAG E VVVIRY 480
Cdd:COG0129 358 -- DR DQDV IR PLD N PY S PT GGLA I L R GN L A P DG AV VKTAGVDE SM L V F E GPA R VF D S EEE AV EA ILGGK I KAG D VVVIRY 435
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 481 EGPKGGPGM Q EML Y PT TY LK S MGLGKS C AL L TDGRFSGGT S GLSIGH A SPEAA S GG T I G LV Q DGDIITIDIP S R SIT L D V 560
Cdd:COG0129 436 EGPKGGPGM R EML S PT SA LK G MGLGKS V AL I TDGRFSGGT R GLSIGH V SPEAA E GG P I A LV E DGDIITIDIP A R TLD L L V 515
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 520914136 561 AED ELA A RRA K qdelg WKP v DRQ R EV S FA L KA YA SMAT SA D KGAV R D KS 609
Cdd:COG0129 516 SDE ELA R RRA A ----- WKP - PEP R VT S GV L AK YA KLVS SA S KGAV T D PP 558
ilvD
TIGR00110 dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth ...
24-607
0e+00
dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth step in valine and isoleucine biosynthesis. It contains a catalytically essential [4Fe-4S] cluster This model generates scores of up to 150 bits vs. 6-phosphogluconate dehydratase, a homologous enzyme. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272910
Cd Length: 535
Bit Score: 879.05
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 24 ATG VK DEDFGKP I I A V V NS F T QF VPGH V HL K D MG Q L V AGE IE K AGG I A K EFNTIAV D DGIAMGH G GM L YSLPSRE L IADS 103
Cdd:TIGR00110 1 ATG FT DEDFGKP F I G V A NS Y T TI VPGH M HL R D LA Q A V KEG IE A AGG V A F EFNTIAV C DGIAMGH E GM K YSLPSRE I IADS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 104 VE Y MVNAH CA D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA G K TKL SDQ I IKLDLVD A MIQG A DPTV S DQQS E Q 183
Cdd:TIGR00110 81 VE T MVNAH RF D GL VCI PS CDKITPGM L MAA A RLNIP S IFV T GGPM LP G H TKL GKK I DLVSAFE A VGEY A AGKI S EEEL E E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 184 V ERSACP T CGSCSGMFTAN S M N CLTEALGLS Q PG NGS MLAT H A DREQLFI N A GKRIV D L TRRYYE qddesal PR N I ANRD 263
Cdd:TIGR00110 161 I ERSACP G CGSCSGMFTAN T M A CLTEALGLS L PG CST MLAT S A EKKRIAK N S GKRIV E L VKKNIK ------- PR D I LTKE 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 264 AFENA MAL D I A M GGS S NTVLHLLA A A Q E GEI D FDMN D I D EM SR R VPH LCKV APS TQKY h MED V HRAGG VM A I L G ELDR A G 343
Cdd:TIGR00110 234 AFENA ITV D M A L GGS T NTVLHLLA I A N E AGV D LSLD D F D RL SR K VPH IASL APS GKYV - MED L HRAGG IP A V L K ELDR E G 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 344 LL N G S T S TV L G M T MQQQ L AEYDIMQTENE evlkffragpagirttqafsqdcrwdrldddreng C IR SKE N AFS QEGGLA 423
Cdd:TIGR00110 313 LL H G D T L TV T G K T LGEI L EQAPVIPEGQD ----------------------------------- V IR PLD N PVH QEGGLA 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 424 V L S GN I A VD G CI VK T AGVDE ENL KF Q GPA I VFES QDS A VDG ILGGK V K A G E VVVIRYEGPKGGPGM Q EML Y PT TYL K S MG 503
Cdd:TIGR00110 358 I L K GN L A PN G AV VK I AGVDE DMT KF E GPA K VFES EEE A LEA ILGGK I K E G D VVVIRYEGPKGGPGM P EML A PT SAI K G MG 437
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 504 LGKS C AL L TDGRFSGGT S GL S IGH A SPEAA S GG T I G LV Q DGDII T IDIP S R SIT L D V AED ELA A RRA KQDELGW kpvdrq 583
Cdd:TIGR00110 438 LGKS V AL I TDGRFSGGT R GL C IGH V SPEAA E GG P I A LV E DGDII I IDIP N R KLD L Q V SDE ELA E RRA SWKAPEP ------ 511
570 580
....*....|....*....|....
gi 520914136 584 R E V SFA L KA YA SMAT SAD K GAV R D 607
Cdd:TIGR00110 512 R Y V KGY L AK YA KLVS SAD E GAV L D 535
ILVD_EDD
pfam00920 Dehydratase family;
34-604
0e+00
Dehydratase family;
Pssm-ID: 459998
Cd Length: 513
Bit Score: 848.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 34 KPII AVV NS FTQF VP G HVHL KDMGQL V AGEIEK AGG IAK EFNTI A V D DGIAMGH G GM L YSLPSRELIADS V E Y M VN AH CA 113
Cdd:pfam00920 1 KPII GIA NS YSDL VP C HVHL RELAEA V KEGVRE AGG VPA EFNTI G V C DGIAMGH E GM R YSLPSRELIADS I E E M LR AH PF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 114 D AM V C I SN CDKI T PGM M MAA M RLNIP V IFVSGGPM EA G KT klsdqii KL D LVD A MIQG A DPTV S DQQSEQV ER S ACP T CG 193
Cdd:pfam00920 81 D GL V L I GG CDKI V PGM L MAA A RLNIP A IFVSGGPM LP G GS ------- GT D EFE A VGAY A AGKI S EEELLEI ER A ACP G CG 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 194 SC S GM F TAN S M N CL T EALGLS Q PG NGSML A TH A D R EQ L FIN AG K RIV D L TR ryyeqdd E SAL PR N I AN R D AFENA MAL D I 273
Cdd:pfam00920 154 SC G GM G TAN T M A CL A EALGLS L PG SATIP A VS A E R LR L ARE AG R RIV E L VE ------- E DIK PR D I LT R K AFENA IVV D M 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 274 A M GGS S N T VLHLLA A A Q E GEI D FDMN D I D EM SR R VP H L CKVA PS t Q KY H MED V HRAGGV M A I L G EL DR A g LL N G STS TV L 353
Cdd:pfam00920 227 A L GGS T N A VLHLLA I A R E AGV D LTLD D F D RI SR K VP L L ADLK PS - G KY L MED F HRAGGV P A V L K EL LD A - LL H G DVL TV T 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 354 G M T MQQQ LA E ydimqteneevlkffragpagirttqafsqdcrwdrl DDD R ENGC IR SKE N AF S QE GGLAVL S GN I A V DG 433
Cdd:pfam00920 305 G K T LGEN LA D ------------------------------------- AEV R DQDV IR PLD N PI S PT GGLAVL K GN L A P DG 347
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 434 CI VKT AG VD E E N L K F Q GPA I VF E S QDS A VDG IL G GK V KAG E VVVIRYEGPKGGPGM Q EML Y PT TY L KSM GLGK SC AL L TD 513
Cdd:pfam00920 348 AV VKT SA VD P E M L V F E GPA R VF D S EED A LAA IL D GK I KAG D VVVIRYEGPKGGPGM P EML T PT SA L LGA GLGK DV AL I TD 427
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 514 GRFSG GTS G L SIGH A SPEAA S GG T I G LV Q DGDII T IDIP S R SIT L D V AED ELAARRA K qdelg WKP VDRQREVSFA L KA Y 593
Cdd:pfam00920 428 GRFSG ASR G P SIGH V SPEAA V GG P I A LV R DGDII R IDIP N R TLD L L V SDE ELAARRA A ----- WKP PEPKVKGRGY L AK Y 502
570
....*....|.
gi 520914136 594 A SMAT SA DK GA 604
Cdd:pfam00920 503 A KLVS SA SE GA 513
Name
Accession
Description
Interval
E-value
PRK12448
PRK12448 dihydroxy-acid dehydratase; Provisional
2-613
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237104
Cd Length: 615
Bit Score: 1404.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 2 PKYRS A TTTHGRNMAGARALWRATG V KDEDFGKPIIAVVNSFTQFVPGHVHLKD M GQLVA G EIE K AGG I AKEFNTIAVDD 81
Cdd:PRK12448 1 PKYRS R TTTHGRNMAGARALWRATG M KDEDFGKPIIAVVNSFTQFVPGHVHLKD L GQLVA R EIE A AGG V AKEFNTIAVDD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 82 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM M MAA M RLNIPV I FVSGGPMEAGKTKLSD Q IIK 161
Cdd:PRK12448 81 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM L MAA L RLNIPV V FVSGGPMEAGKTKLSD K IIK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 162 LDLVDAM IQG ADP T VSD QQSE Q V ERSACPTCGSCSGMFTANSMNCLTEALGLS Q PGNGS M LATHADR E QLF IN AG K RIV D 241
Cdd:PRK12448 161 LDLVDAM VAA ADP S VSD EDVA Q I ERSACPTCGSCSGMFTANSMNCLTEALGLS L PGNGS L LATHADR K QLF LE AG R RIV E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 242 L TR RYYEQDDES A LPR N IA NRD AFENAM A LDIAMGGS S NTVLHLLAAAQE G E I DF D M N DID EM SR R VP H LCKVAP S TQKY 321
Cdd:PRK12448 241 L AK RYYEQDDES V LPR S IA TKA AFENAM T LDIAMGGS T NTVLHLLAAAQE A E V DF T M A DID RL SR K VP C LCKVAP N TQKY 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 322 HMEDVHRAGG V M A ILGELDRAGLL NGSTS TV L G M T MQQQ L AEY DIM Q T EN E E V LK FFRA G P A GIRTT Q AFSQDCRWD R LD 401
Cdd:PRK12448 321 HMEDVHRAGG I M G ILGELDRAGLL HTDVP TV H G L T LGEA L DQW DIM R T QD E A V KE FFRA A P G GIRTT V AFSQDCRWD S LD 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 402 D DRENGCIRS K E N A F S QE GGLAVL S GNIA V DGCIVKTAGVDE EN LKF Q GPA I VFESQD S AV DG ILGGKVKAG E VVVIRYE 481
Cdd:PRK12448 401 T DRENGCIRS V E H A Y S KD GGLAVL Y GNIA E DGCIVKTAGVDE SI LKF T GPA R VFESQD D AV EA ILGGKVKAG D VVVIRYE 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 482 GPKGGPGMQEMLYPT T YLKS M GLGK S CAL L TDGRFSGGTSGLSIGH A SPEAASGG T IGLV Q DGDII T IDIP S RSI T L D V A 561
Cdd:PRK12448 481 GPKGGPGMQEMLYPT S YLKS K GLGK A CAL I TDGRFSGGTSGLSIGH V SPEAASGG A IGLV E DGDII E IDIP N RSI N L L V S 560
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 520914136 562 ED ELAARRA K Q DEL G --- WKP VD R Q R E VSFALKAYA SM ATSADKGAVRDKSKL E G 613
Cdd:PRK12448 561 DE ELAARRA A Q EAR G dka WKP KN R E R K VSFALKAYA AL ATSADKGAVRDKSKL G G 615
IlvD
COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, ...
1-609
0e+00
Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; Dihydroxyacid dehydratase/phosphogluconate dehydratase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439899
Cd Length: 558
Bit Score: 1020.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 1 MPK Y RS A T T T H GR NM A G ARAL W RATG VK DEDFGKPII AVV NS FTQF VPGHVHL K D MGQL V AGE I EK AGG IAK EFNTIAV D 80
Cdd:COG0129 1 MPK M RS D T V T K GR ER A P ARAL L RATG LT DEDFGKPII GIA NS WNEI VPGHVHL D D LAEA V KEG I RA AGG VPF EFNTIAV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 81 DGIAMGH G GM L YSLPSRELIADS V E Y MVNAHC A D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA GK TK l SDQII 160
Cdd:COG0129 81 DGIAMGH E GM R YSLPSRELIADS I E T MVNAHC F D GL VCI PG CDKITPGM L MAA A RLNIP S IFV Y GGPM LP GK YD - GKDLD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 161 KL D LVD A MIQG A DPTV SD QQSEQV ER S ACP T CGSCSGMFTAN S M N CLTEALGLS Q PG N G SML A TH A D R EQ L FIN AG K RIV 240
Cdd:COG0129 160 IV D VFE A VGAY A AGKI SD EELKEI ER N ACP G CGSCSGMFTAN T M A CLTEALGLS L PG S G TIP A VS A E R RR L ARE AG R RIV 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 241 D L TRR yyeqdde SAL PR N I AN R D AFENA M A L D I A M GGS S NTVLHLLA A A Q E GEI D FDMN D I D EM SRR V PHLC KVA PS T q K 320
Cdd:COG0129 240 E L VEK ------- DIK PR D I LT R E AFENA I A V D M A L GGS T NTVLHLLA I A H E AGV D LTLD D F D RI SRR T PHLC DLK PS G - K 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 321 YHMED V HRAGG VM A ILG EL DR AGLL N G STS TV L G M T MQQQ LA EY DI mqteneevlkffragpagirttqafsqdcrwdrl 400
Cdd:COG0129 312 YHMED L HRAGG IP A VMK EL LD AGLL H G DCL TV T G K T LAEN LA DA DI ---------------------------------- 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 401 dd DR ENGC IR SKE N AF S QE GGLA V L S GN I A V DG CI VKTAGVDE EN L K F Q GPA I VF E S QDS AV DG ILGGK V KAG E VVVIRY 480
Cdd:COG0129 358 -- DR DQDV IR PLD N PY S PT GGLA I L R GN L A P DG AV VKTAGVDE SM L V F E GPA R VF D S EEE AV EA ILGGK I KAG D VVVIRY 435
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 481 EGPKGGPGM Q EML Y PT TY LK S MGLGKS C AL L TDGRFSGGT S GLSIGH A SPEAA S GG T I G LV Q DGDIITIDIP S R SIT L D V 560
Cdd:COG0129 436 EGPKGGPGM R EML S PT SA LK G MGLGKS V AL I TDGRFSGGT R GLSIGH V SPEAA E GG P I A LV E DGDIITIDIP A R TLD L L V 515
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 520914136 561 AED ELA A RRA K qdelg WKP v DRQ R EV S FA L KA YA SMAT SA D KGAV R D KS 609
Cdd:COG0129 516 SDE ELA R RRA A ----- WKP - PEP R VT S GV L AK YA KLVS SA S KGAV T D PP 558
ilvD
TIGR00110 dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth ...
24-607
0e+00
dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth step in valine and isoleucine biosynthesis. It contains a catalytically essential [4Fe-4S] cluster This model generates scores of up to 150 bits vs. 6-phosphogluconate dehydratase, a homologous enzyme. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272910
Cd Length: 535
Bit Score: 879.05
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 24 ATG VK DEDFGKP I I A V V NS F T QF VPGH V HL K D MG Q L V AGE IE K AGG I A K EFNTIAV D DGIAMGH G GM L YSLPSRE L IADS 103
Cdd:TIGR00110 1 ATG FT DEDFGKP F I G V A NS Y T TI VPGH M HL R D LA Q A V KEG IE A AGG V A F EFNTIAV C DGIAMGH E GM K YSLPSRE I IADS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 104 VE Y MVNAH CA D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA G K TKL SDQ I IKLDLVD A MIQG A DPTV S DQQS E Q 183
Cdd:TIGR00110 81 VE T MVNAH RF D GL VCI PS CDKITPGM L MAA A RLNIP S IFV T GGPM LP G H TKL GKK I DLVSAFE A VGEY A AGKI S EEEL E E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 184 V ERSACP T CGSCSGMFTAN S M N CLTEALGLS Q PG NGS MLAT H A DREQLFI N A GKRIV D L TRRYYE qddesal PR N I ANRD 263
Cdd:TIGR00110 161 I ERSACP G CGSCSGMFTAN T M A CLTEALGLS L PG CST MLAT S A EKKRIAK N S GKRIV E L VKKNIK ------- PR D I LTKE 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 264 AFENA MAL D I A M GGS S NTVLHLLA A A Q E GEI D FDMN D I D EM SR R VPH LCKV APS TQKY h MED V HRAGG VM A I L G ELDR A G 343
Cdd:TIGR00110 234 AFENA ITV D M A L GGS T NTVLHLLA I A N E AGV D LSLD D F D RL SR K VPH IASL APS GKYV - MED L HRAGG IP A V L K ELDR E G 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 344 LL N G S T S TV L G M T MQQQ L AEYDIMQTENE evlkffragpagirttqafsqdcrwdrldddreng C IR SKE N AFS QEGGLA 423
Cdd:TIGR00110 313 LL H G D T L TV T G K T LGEI L EQAPVIPEGQD ----------------------------------- V IR PLD N PVH QEGGLA 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 424 V L S GN I A VD G CI VK T AGVDE ENL KF Q GPA I VFES QDS A VDG ILGGK V K A G E VVVIRYEGPKGGPGM Q EML Y PT TYL K S MG 503
Cdd:TIGR00110 358 I L K GN L A PN G AV VK I AGVDE DMT KF E GPA K VFES EEE A LEA ILGGK I K E G D VVVIRYEGPKGGPGM P EML A PT SAI K G MG 437
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 504 LGKS C AL L TDGRFSGGT S GL S IGH A SPEAA S GG T I G LV Q DGDII T IDIP S R SIT L D V AED ELA A RRA KQDELGW kpvdrq 583
Cdd:TIGR00110 438 LGKS V AL I TDGRFSGGT R GL C IGH V SPEAA E GG P I A LV E DGDII I IDIP N R KLD L Q V SDE ELA E RRA SWKAPEP ------ 511
570 580
....*....|....*....|....
gi 520914136 584 R E V SFA L KA YA SMAT SAD K GAV R D 607
Cdd:TIGR00110 512 R Y V KGY L AK YA KLVS SAD E GAV L D 535
ILVD_EDD
pfam00920 Dehydratase family;
34-604
0e+00
Dehydratase family;
Pssm-ID: 459998
Cd Length: 513
Bit Score: 848.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 34 KPII AVV NS FTQF VP G HVHL KDMGQL V AGEIEK AGG IAK EFNTI A V D DGIAMGH G GM L YSLPSRELIADS V E Y M VN AH CA 113
Cdd:pfam00920 1 KPII GIA NS YSDL VP C HVHL RELAEA V KEGVRE AGG VPA EFNTI G V C DGIAMGH E GM R YSLPSRELIADS I E E M LR AH PF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 114 D AM V C I SN CDKI T PGM M MAA M RLNIP V IFVSGGPM EA G KT klsdqii KL D LVD A MIQG A DPTV S DQQSEQV ER S ACP T CG 193
Cdd:pfam00920 81 D GL V L I GG CDKI V PGM L MAA A RLNIP A IFVSGGPM LP G GS ------- GT D EFE A VGAY A AGKI S EEELLEI ER A ACP G CG 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 194 SC S GM F TAN S M N CL T EALGLS Q PG NGSML A TH A D R EQ L FIN AG K RIV D L TR ryyeqdd E SAL PR N I AN R D AFENA MAL D I 273
Cdd:pfam00920 154 SC G GM G TAN T M A CL A EALGLS L PG SATIP A VS A E R LR L ARE AG R RIV E L VE ------- E DIK PR D I LT R K AFENA IVV D M 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 274 A M GGS S N T VLHLLA A A Q E GEI D FDMN D I D EM SR R VP H L CKVA PS t Q KY H MED V HRAGGV M A I L G EL DR A g LL N G STS TV L 353
Cdd:pfam00920 227 A L GGS T N A VLHLLA I A R E AGV D LTLD D F D RI SR K VP L L ADLK PS - G KY L MED F HRAGGV P A V L K EL LD A - LL H G DVL TV T 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 354 G M T MQQQ LA E ydimqteneevlkffragpagirttqafsqdcrwdrl DDD R ENGC IR SKE N AF S QE GGLAVL S GN I A V DG 433
Cdd:pfam00920 305 G K T LGEN LA D ------------------------------------- AEV R DQDV IR PLD N PI S PT GGLAVL K GN L A P DG 347
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 434 CI VKT AG VD E E N L K F Q GPA I VF E S QDS A VDG IL G GK V KAG E VVVIRYEGPKGGPGM Q EML Y PT TY L KSM GLGK SC AL L TD 513
Cdd:pfam00920 348 AV VKT SA VD P E M L V F E GPA R VF D S EED A LAA IL D GK I KAG D VVVIRYEGPKGGPGM P EML T PT SA L LGA GLGK DV AL I TD 427
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 514 GRFSG GTS G L SIGH A SPEAA S GG T I G LV Q DGDII T IDIP S R SIT L D V AED ELAARRA K qdelg WKP VDRQREVSFA L KA Y 593
Cdd:pfam00920 428 GRFSG ASR G P SIGH V SPEAA V GG P I A LV R DGDII R IDIP N R TLD L L V SDE ELAARRA A ----- WKP PEPKVKGRGY L AK Y 502
570
....*....|.
gi 520914136 594 A SMAT SA DK GA 604
Cdd:pfam00920 503 A KLVS SA SE GA 513
PRK00911
PRK00911 dihydroxy-acid dehydratase; Provisional
5-608
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 234861
Cd Length: 552
Bit Score: 792.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 5 RS ATT T H G RNM A GA R ALW RATG VK DEDF G KP I I AVV NS FTQFV P GHV HL KDMGQL V AGEIEK AGG IAK EFNTI A V D DGIA 84
Cdd:PRK00911 2 RS DMI T K G VER A PH R SML RATG LT DEDF D KP F I GIA NS WNEIT P CNI HL NELADA V KEGVRA AGG VPF EFNTI G V S DGIA 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 85 MGH G GM L YSL P SRE L IADS V E YM VNAH CA D AM V C I SN CDK IT PGM M MAA M RLN I P V IFV S GGP MEA G kt K L SDQ ii K L D L 164
Cdd:PRK00911 82 MGH E GM K YSL V SRE V IADS I E TV VNAH WF D GL V A I PG CDK NM PGM L MAA A RLN V P S IFV Y GGP ILP G -- R L KGK -- D L T L 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 165 V D --- A MIQG A DPTV S DQQSEQV ER S ACP TC GSC S GMFTAN S M N CL T EALG L S Q PG N G SML A TH A D R EQ L FIN AG KRI V D 241
Cdd:PRK00911 158 V S vfe A VGAY A AGKI S EEELKEI ER N ACP GA GSC G GMFTAN T M A CL I EALG M S L PG S G TIP A VD A E R DE L ARE AG EAV V E 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 242 L TRRYY eqddesa L PR N I AN R D AFENA M A L D I A M GGS S N T VLHLLA A A Q E GEI D FDMN D IDEM S R R V PHL CKVA PS T q KY 321
Cdd:PRK00911 238 L LEKDI ------- K PR D I LT R E AFENA I A V D M A L GGS T N A VLHLLA I A H E AGV D LTLD D FNRI S K R T PHL ADLK PS G - KY 309
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 322 H MED V H R AGG VM A ILG EL DR AGLL N G STS TV L G M T MQQQ LA EYDI mqt ENEE V lkffragpagirttqafsqdcrwdrld 401
Cdd:PRK00911 310 V MED L H E AGG IP A VMK EL LD AGLL H G DCL TV T G K T LAEN LA DAPD --- PDQD V --------------------------- 359
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 402 ddrengc IR SKE N AF S QE GGLA V L S GN I A VD G CI VK T AGV DE E nl K F Q GPA I VF E S QDS A VDG IL G GK V KAG E VVVIRYE 481
Cdd:PRK00911 360 ------- IR PLD N PI S PT GGLA I L K GN L A PE G AV VK I AGV KP E -- M F T GPA R VF D S EEE A MEA IL A GK I KAG D VVVIRYE 430
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 482 GPKGGPGM Q EML Y PT TYLKSM GLG KSC AL L TDGRFSGGT S GL SI GH A SPEAA S GG T I G LV Q DGDIITID I P S R SITLD V A 561
Cdd:PRK00911 431 GPKGGPGM R EML A PT SAIVGA GLG DDV AL I TDGRFSGGT R GL CV GH V SPEAA V GG P I A LV E DGDIITID A P N R TLDVL V S 510
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 520914136 562 ED ELA A RRA K qdelg WKP V d RQREVSFA L KA YA SMAT SA DK GAV R D K 608
Cdd:PRK00911 511 DE ELA R RRA A ----- WKP P - EPKYKRGV L AK YA KLVS SA ST GAV T D P 551
PRK06131
PRK06131 dihydroxy-acid dehydratase; Validated
2-607
2.18e-120
dihydroxy-acid dehydratase; Validated
Pssm-ID: 235708
Cd Length: 571
Bit Score: 368.36
E-value: 2.18e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 2 PKY RS ATT -- THGRNMAGA R ALWRAT G VK DE D F - G K PII AVV N SFTQFV P GHV H LKDMGQL V AGEIEK AGG IAK EF NT I A 78
Cdd:PRK06131 3 GLL RS LAW fg DDDFRAFYH R SFMKNQ G YP DE L F d G R PII GIC N TWSDLN P CNA H FRQLAER V KRGVLE AGG FPV EF PV I S 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 79 V ddgiam G HGG ----- MLY slps R E L I A DS VE Y M VNAHCA D AM V CISN CDK I TP GMM M A A MRLNI P V I FV SGGPM EA GK T 153
Cdd:PRK06131 83 L ------ G ESF lrpta MLY ---- R N L A A MD VE E M IRGYPI D GV V LLGG CDK T TP ALL M G A ASVDL P A I VL SGGPM LN GK H 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 154 K LSD ----- QII K L - DLVD A miq G adp TVSDQQSEQV E RSACPTC G S C SG M F TA NS M N C LT EALG L S Q PGN GSML A TH A D 227
Cdd:PRK06131 153 K GER lgsgt DVW K Y w EELR A --- G --- EIDLEEFLEA E AGMARSA G T C NT M G TA ST M A C MA EALG M S L PGN AAIP A VD A R 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 228 R EQLFINA G K RIV DLTR ryyeqdd E SAL P RN I AN R D AFENA MALDI A M GGS S N T V L HL L A A A QEGEIDF D MN D I D EMS R R 307
Cdd:PRK06131 227 R IRMAELT G R RIV EMVH ------- E DLK P SD I LT R E AFENA IRVNA A I GGS T N A V I HL I A I A GRAGVEL D LD D W D RIG R D 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 308 VP H L CKVA PS TQ k Y H MED VHR AGG VM A I L G EL dr AG LL NGSTS TV L G M T MQQQ LA E ydi MQTE N EE V lkffragpagirt 387
Cdd:PRK06131 300 VP V L VNLQ PS GE - Y L MED FYY AGG LP A V L R EL -- GE LL HLDAL TV N G K T LGEN LA G --- APVY N DD V ------------- 360
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 388 tqafsqdcrwdrldddrengc IR SKE N AFSQ EGG L AVL S GN I A V DG CIV K TAGVDE E N LK FQ G P A I VFE SQDSAVDG I -- 465
Cdd:PRK06131 361 --------------------- IR PLD N PLKP EGG I AVL R GN L A P DG AVI K PSAASP E L LK HE G R A V VFE GYEDYKAR I dd 419
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 466 -- L G gk V KAGE V V V I R YE GPKG G PGM Q E -- MLYPTTY L KSM G L g K SCALLT D G R F SG GTS G LSIG H AS PEAA S GG TIG LV 541
Cdd:PRK06131 420 pd L D -- V DEDT V L V L R NA GPKG Y PGM P E vg NMPIPKK L LRQ G V - K DMVRIS D A R M SG TAY G TVVL H VA PEAA A GG PLA LV 496
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 520914136 542 QD GD I I TI D I P S R SIT L D V AED ELA A RRA K qdelg W K P VDRQR E VSFA l KA Y ASMATS AD K G AVR D 607
Cdd:PRK06131 497 RT GD R I RL D V P A R RLD L L V SDE ELA R RRA A ----- W P P PPPRA E RGYQ - EL Y RDHVLQ AD E G CDF D 556
PRK13016
PRK13016 dihydroxy-acid dehydratase; Provisional
26-604
5.74e-107
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237271
Cd Length: 577
Bit Score: 334.00
E-value: 5.74e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 26 G VKD EDF - GKP I IA VV N SFTQFV P G H V H LKDMGQL V AGEIEK AGG IAK E FNTIAVDDGI a MGHGG MLY slps R E L I A DSV 104
Cdd:PRK13016 33 G YAP EDF d GKP V IA IL N TWSDAN P C H G H FRERVED V KRGVLQ AGG FPL E LPALSLSENF - VKPTT MLY ---- R N L L A MET 107
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 105 E YMVNA H CA D AM V CISN CDK I TPG MM M A A MRLNI P V I FVSG GPM ---- EA GK T -- KL SD QIIKL D LVD A miqgad PTVSD 178
Cdd:PRK13016 108 E ELIRS H PV D GA V LMGG CDK T TPG LV M G A ISMGL P M I YLPA GPM lrgn YR GK V lg SG SD AWKYW D ERR A ------ GNITQ 181
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 179 QQSEQV E RSACPTC G S C SG M F TA NS M NCLT EALGL SQ PG NG S ML A TH A DREQLFINA G K RIV DLTR ryyeqdd E SAL P RN 258
Cdd:PRK13016 182 AEWLEI E GGIARSY G T C MT M G TA ST M TAIA EALGL TL PG AS S IP A AD A NHQRMAALC G R RIV EMVW ------- E DLT P SQ 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 259 I ANRD AFENA MALDI A M G G S S N T V L HL L A A A QEGEIDFDMN D I D EMS R R VP HLCKVA PS TQK Y H MED VHR AGG VM A ILGE 338
Cdd:PRK13016 255 I LTKA AFENA ITVAM A T G C S T N A V I HL I A M A RRAGVPLSLD D L D RCG R T VP VIANIR PS GKT Y L MED FFY AGG LR A LMKQ 334
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 339 L dr AGL L NGSTS TV L G M T MQQQ L AE ydi MQTE N EE V lkffragpagirttqafsqdcrwdrldddrengc IR SKE N AFSQ 418
Cdd:PRK13016 335 L -- GDK L HLDAL TV T G K T LGDN L EG --- AKVY N DD V ---------------------------------- IR PLD N PVYA 375
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 419 EG G LAVL S GN I A V DG CIV K T A GV D EEN L KFQ GPA I VF E S QDS --- A V D G i LGGK V KAGE V V V I R YE GP K GGPGM Q E -- ML 493
Cdd:PRK13016 376 EG S LAVL R GN L A P DG AVI K P A AC D PKF L VHR GPA L VF D S YPE mka A I D D - ENLD V TPDH V M V L R NA GP Q GGPGM P E wg ML 454
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 494 - Y P TTY LK s M G L g KSCALLT D G R F SG GTS G LSIG H AS PEA AS GG TIG LV QD GDII TI D I P S R SIT L D V AED ELA A RRA K q 572
Cdd:PRK13016 455 p I P KKL LK - Q G V - RDMVRIS D A R M SG TSY G ACVL H VA PEA YV GG PLA LV RT GDII EL D V P A R RLH L L V SDE ELA R RRA A - 531
570 580 590
....*....|....*....|....*....|..
gi 520914136 573 delg W K P VD R QR E VSFA l KAYASMATS ADKG A 604
Cdd:PRK13016 532 ---- W Q P PE R RY E RGYG - WMFSQHVEQ ADKG C 558
PRK13017
PRK13017 dihydroxy-acid dehydratase; Provisional
33-607
6.62e-101
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237272
Cd Length: 596
Bit Score: 318.83
E-value: 6.62e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 33 GKPII AVVNSFTQFV P GHV H LKDMGQL V AGE I EK AGGI AK EF NTIAVDDG i AMGHGGM L Y slps R E L IADSVEYMVNAHC 112
Cdd:PRK13017 46 GKPII GIAQTGSDLS P CNR H HLELAER V KEG I RD AGGI PM EF PVHPIQET - GKRPTAA L D ---- R N L AYLGLVEILYGYP 120
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 113 A D AM V CISN CDK I TP GMM MAA MRLNI P V I FV SGGPM ---- EA G KTKL S DQI I kldl VD A MIQG A DPTVSDQQSEQVER S A 188
Cdd:PRK13017 121 L D GV V LTTG CDK T TP ACL MAA ATVDL P A I VL SGGPM ldgw HE G ERVG S GTV I ---- WK A RELL A AGEIDYEEFMELVA S S 196
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 189 C P TC G S C SG M F TA NS MN C L T EALG L S Q PG NGSML A THAD R E Q LFINA GKRIV DLTR ryyeqdd E SAL P RN I AN R D AFENA 268
Cdd:PRK13017 197 A P SV G H C NT M G TA ST MN A L A EALG M S L PG CAAIP A PYRE R G Q MAYAT GKRIV EMVW ------- E DLK P SD I LT R E AFENA 269
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 269 MALDI A M GGS S N TVL HL L A A A QEGEIDFDMN D IDEMSRR VP H L CKVA P ST q KY HM ED V HRAGGV M A I L G EL D RAGLL N G S 348
Cdd:PRK13017 270 IVVNS A I GGS T N API HL I A I A RHAGVELSLD D WQRVGED VP L L VNLQ P AG - KY LG ED F HRAGGV P A V L A EL L RAGLL H G D 348
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 349 TS TV L G M T MQQQL A E ydi MQTENEE V lkffragpagirttqafsqdcrwdrldddrengc IR SKENAFSQEG G LA VL S GN 428
Cdd:PRK13017 349 AL TV S G R T IGENI A G --- APAPDRD V ---------------------------------- IR PYDAPLKERA G FL VL R GN 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 429 IA v D GC I V KT AGVD EE NLK ----------- F Q G P A I VF ES -------- Q D S A V D gilggk VKAGEVV VIR YE GP K G G PG M 489
Cdd:PRK13017 392 LF - D SA I M KT SVIS EE FRE rylsepgdena F E G R A V VF DG pedyhari D D P A L D ------ IDEHCIL VIR GA GP V G Y PG S 464
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 490 Q E -- MLY P TTY L KSM G L g K S CALLT DGR F SG GTSGL SI GH ASPEAA S GG TIG L VQD GD I I T ID IPS R SITLD V AED ELA A 567
Cdd:PRK13017 465 A E vv NMQ P PAA L LKR G I - R S LPCIG DGR Q SG TSGSP SI LN ASPEAA V GG GLA L LRT GD R I R ID LNK R RVDVL V SDE ELA R 543
570 580 590 600
....*....|....*....|....*....|....*....|
gi 520914136 568 RRA K qdelg W KP VDRQREVSFA l KA Y ASMATSADK GA VRD 607
Cdd:PRK13017 544 RRA A ----- L KP PVPPSQTPWQ - EL Y RKHVGQLST GA CLE 577
yjhG_yagF
TIGR03432 putative dehydratase, YjhG/YagF family; This homolog of dihydroxy-acid dehydratases has an odd, ...
26-573
1.98e-57
putative dehydratase, YjhG/YagF family; This homolog of dihydroxy-acid dehydratases has an odd, sparse distribution. Members are found in two Acidobacteria, two Planctomycetes, Bacillus clausii KSM-K16, and (in two copies each) in strains K12-MG1655 and W3110 of Escherichia coli. The local context is not well conserved, but a few members are adjacent to homologs of the gluconate:H+ symporter (see TIGR00791). [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 163260
Cd Length: 640
Bit Score: 204.26
E-value: 1.98e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 26 G VKDE D f G K PI IAVVNS ftqfvp GH VHLKDMGQLV A G EI EKA G GIA ke F NTIAV D -- DG IAM G HG GM LY SLP S R ELI A DS 103
Cdd:TIGR03432 66 G LRAA D - G T PI ALGYHT ------ GH WEVGLLMKAA A E EI KRD G AVP -- F AGFVS D pc DG RTQ G TT GM FD SLP Y R NDA A MV 136
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 104 VEYMVNAH - CADAMVC I SN CDK IT P G MMMA - A MRLNI P VIF V S GG --- P M E A G KTKLSD Q I I kldlvdamiq GA DPTVSD 178
Cdd:TIGR03432 137 MRRLIRSL p TRKGVIG I AT CDK GL P A MMMA l A ATHHL P TVL V P GG vtl P P E V G EDAGKV Q T I ---------- GA RFSNGE 206
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 179 QQS E QVERSA C PT C G S ---- C SGMF TA NSMNCLT EALGL SQ P gn G S M LA THA dr EQLFINAGK R I vdl T R RYY E QDDESA 254
Cdd:TIGR03432 207 ITL E EAAEAG C RA C A S pggg C QFLG TA ATSQVVA EALGL AL P -- H S A LA PSG -- QPIWLDMAR R S --- A R AAL E LSQKGL 279
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 255 LP R N I ANRD A F ENAM ALDI A M GGS S N TV LH LL A - A AQE G EIDFDMN D IDEMS R R VP H L CKVA P STQKY H ME - D V HR AGGV 332
Cdd:TIGR03432 280 ST R D I LTDK A I ENAM VVHA A F GGS T N LL LH IP A i A HAA G CRRPTVD D WTRIN R K VP R L VDAL P NGPVG H PT v R V FL AGGV 359
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 333 MAILGE L D RAGLL NGSTS TV L G M T MQQQ L AEYD im QT E NEEVL K ffragp AGI R TT qafsqdcrw D RL D D D R eng C I R S K 412
Cdd:TIGR03432 360 PEVMLH L R RAGLL HEDVL TV T G E T LGEN L DWWE -- NS E RRARM K ------ QRL R ER --------- D GV D P D D --- V I M S P 419
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 413 EN A fs QEG GL AVL ---- S GN I A VD G CIV K TAGV D ------ EENLKFQ GPA I VF E S QD SA VDG I LG GK VK AG E V V V IRYE G 482
Cdd:TIGR03432 420 AQ A -- KAR GL TST vtfp K GN L A PE G SVI K STAI D psvvde DGVYRHT GPA R VF S S EK SA IAA I KH GK IE AG D V L V LIGR G 497
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520914136 483 P K G G p GM Q E MLYP T TY LK SMGL GK SC AL L TD G RFSG GTS G LS IGH AS PEA AS GG T IG L V Q DGD I I T I D I PSR ---- SIT L 558
Cdd:TIGR03432 498 P S G T - GM E E TYQV T SA LK YLSF GK HV AL I TD A RFSG VST G AC IGH VG PEA LA GG P IG K V R DGD L I E I I I DRN tleg TVN L 576
570 580
....*....|....*....|....*
gi 520914136 559 DVA ED E ---------- LAAR RAKQ D 573
Cdd:TIGR03432 577 VGT ED G nqlpeegaav LAAR PLRP D 601
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
