|
Name |
Accession |
Description |
Interval |
E-value |
| IolD |
COG3962 |
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism ... |
1-646 |
0e+00 |
|
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism [Carbohydrate transport and metabolism];
Pssm-ID: 443162 [Multi-domain] Cd Length: 622 Bit Score: 1124.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 1 MGKLRLTMAQALVKFLDNQYLEVDGETVKFVKGIFAIFGHGNVLGLGQALEQDSGELRLYQGRNEQGMAHAATGFARQSL 80
Cdd:COG3962 2 MKTIRLTVAQALVRFLANQYVERDGEEQPLFAGVFGIFGHGNVAGLGQALEQDPDELPTYQGRNEQGMAHAAIAYAKQKN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 81 RRQILACTSSVGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIEQSYDLSISTNDAFRAVSKYWDRITRPE 160
Cdd:COG3962 82 RRRIMACTSSIGPGATNMVTAAALATANRLPVLLLPGDTFATRQPDPVLQQLEHFHDPTISVNDAFRPVSRYWDRITRPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 161 QLMSACINAMRVLTDPAETGAVTLALPQDVQGEAWDYPQSFFARRVHRLDRRPASQAQLNDAVAAIRASRKPLIICGGGV 240
Cdd:COG3962 162 QLMSALPRAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPPPDPAELARAVELIRAAKRPLIIAGGGV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 241 KYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFQHP 320
Cdd:COG3962 242 RYSEATEALRAFAEATGIPVAETQAGKGALPWDHPLNLGGIGVTGTLAANALAAEADLVIGVGTRLQDFTTGSKTLFANP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 321 DVRFLNINVSNFDAWKLDGIPLLADAREALTALDGALGDTAWQAGWGEQIAAVQSRQMKETHRVYQASFQekgfipeidd 400
Cdd:COG3962 322 DVRFVNINVARFDAYKHDALPVVADAREGLEALTEALAGWRYPAAWTDEAAELKAEWDAEVDRLYAPTNG---------- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 401 hldresvyrefraltdSTLTQSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGV 480
Cdd:COG3962 392 ----------------GLPTQAQVIGAVNEAAGPDDIVVCAAGSLPGDLHKLWRTRDPGTYHVEYGYSCMGYEIAGGLGV 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 481 KLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTEFRFRSAENGQLNGGLVP 560
Cdd:COG3962 456 KLAEPDREVYVMVGDGSYLMLNSELVTSVQEGKKIIVVLLDNHGFGCINRLQMSTGSQSFGTELRDRDTETGRLDGGLLP 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 561 VDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVLPKTMVHKYGSWWNVGVAQQALSERIQRVAQQINEKR 640
Cdd:COG3962 536 VDFAANAASLGAKAYRVTTIAELRAALERAKAADRTTVIVIKTDPKTMTPGGGSWWDVGVAEVSERESVRAARAEYEEAR 615
|
....*.
gi 655997487 641 AQARDY 646
Cdd:COG3962 616 AKQRRY 621
|
|
| myo_inos_iolD |
TIGR04377 |
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5 ... |
5-644 |
0e+00 |
|
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase (iolD), represent one of eight enzymes in a pathway converting myo-inositol to acetyl-CoA. IolD hydrolyzes the cyclic molecule 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione to yield 5-deoxy-D-glucuronic acid. TPP is a cofactor. [Energy metabolism, Sugars]
Pssm-ID: 275170 [Multi-domain] Cd Length: 615 Bit Score: 1048.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 5 RLTMAQALVKFLDNQYLEVDGETVKFVKGIFAIFGHGNVLGLGQALEQDSGELRLYQGRNEQGMAHAATGFARQSLRRQI 84
Cdd:TIGR04377 1 RLTMAQALVRFLAAQYVERDGEEVPFFAGVFAIFGHGNVAGLGEALEEDPDDLPTYRGRNEQGMAHAAIAYAKQKNRRRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 85 LACTSSVGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIEQSYDLSISTNDAFRAVSKYWDRITRPEQLMS 164
Cdd:TIGR04377 81 MACTSSIGPGATNMVTAAALATVNRLPVLLLPGDTFATRQPDPVLQQLEDFSDLTVSVNDAFRPVSRYFDRITRPEQLMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 165 ACINAMRVLTDPAETGAVTLALPQDVQGEAWDYPQSFFARRVHRLDRRPASQAQLNDAVAAIRASRKPLIICGGGVKYSG 244
Cdd:TIGR04377 161 ALPNAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPEPDPAELERAVAAIRAAKKPLIVAGGGVHYSE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 245 AGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFQHPDVRF 324
Cdd:TIGR04377 241 AGEALAAFAEKHGIPVAETQAGKGALPWDHPLNLGAIGVTGTLAANALAAEADLVIAVGTRLQDFTTASKTLFQNPDVRF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 325 LNINVSNFDAWKLDGIPLLADAREALTALDGALGDTAWQAGWGEQIAAVQSRQMKETHRVYQASFQEKGfipeiddhldr 404
Cdd:TIGR04377 321 VNINVARFDAYKHDALPLVADARAGLEALSEALGGYRADSAWAAEAAAAKAAWDAEVDRLYAAEYTAGG----------- 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 405 esvyrefraltdsTLTQSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAE 484
Cdd:TIGR04377 390 -------------LPTQAEVIGAVNRAAGPDDVVVCAAGSLPGDLHKLWRTRDPGGYHMEYGYSCMGYEIAGGLGVKLAE 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 485 PQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTEFRFrsAENGQLNGGLVPVDFA 564
Cdd:TIGR04377 457 PDREVYVMVGDGSYLMLNSELATSVQEGKKIIVVLLDNRGFGCINNLQMSTGGASFNTELRY--EDTGRLDGGLLPVDFA 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 565 AIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVLPKTMVHKYGSWWNVGVAQQALSERIQRVAQQINEKRAQAR 644
Cdd:TIGR04377 535 AHAAALGAKTYKVTTIAELEAALARAKAADRTTLIVIDTDPKTMTEGYGSWWDVGVAEVSERESVRKAREEYEEAKKAQR 614
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
421-624 |
1.09e-111 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 333.89 E-value: 1.09e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 421 QSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMM 500
Cdd:cd02003 1 QTEVLGALNEAIGDDDVVINAAGSLPGDLHKLWRARTPGGYHLEYGYSCMGYEIAAGLGAKLAKPDREVYVLVGDGSYLM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 501 LHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTEFRFRSAENGQLNGGLVPVDFAAIAAGYGCKTWRVTTL 580
Cdd:cd02003 81 LHSEIVTAVQEGLKIIIVLFDNHGFGCINNLQESTGSGSFGTEFRDRDQESGQLDGALLPVDFAANARSLGARVEKVKTI 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 655997487 581 DELKIALEAAQRETVSTLIDIKVLPKTMVHKYGSWWNVGVAQQA 624
Cdd:cd02003 161 EELKAALAKAKASDRTTVIVIKTDPKSMTPGYGSWWDVGVAEVS 204
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
5-605 |
1.90e-101 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 319.80 E-value: 1.90e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 5 RLTMAQALVKFLDNQylevdGetvkfVKGIFAIFGhGNVLGLGQALEQDSGeLRLYQGRNEQGMAHAATGFARqsLRRQI 84
Cdd:COG0028 2 KMTGADALVEALEAE-----G-----VETVFGVPG-GAILPLYDALRRQSG-IRHILVRHEQGAAFMADGYAR--ATGKP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 85 LACTSSVGPGAANMITAAATATANRIPLLLLPGDVFATrqpdpvlqQIEQSYDLSISTNDAFRAVSKYWDRITRPEQLMS 164
Cdd:COG0028 68 GVCLVTSGPGATNLVTGLADAYMDSVPVLAITGQVPTS--------LIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPE 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 165 ACINAMRVLTDPaETGAVTLALPQDVQGEAWDY-PQSFFARRVHRldRRPASQAQLNDAVAAIRASRKPLIICGGGVKYS 243
Cdd:COG0028 140 VLRRAFRIATSG-RPGPVVLDIPKDVQAAEAEEePAPPELRGYRP--RPAPDPEAIEEAAELLAAAKRPVILAGGGARRA 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 244 GAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFqHPDVR 323
Cdd:COG0028 217 GAAEELRALAERLGAPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALAEADLVLAVGARFDDRVTGNWDEF-APDAK 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 324 FLNINVsnfDAWKLD-----GIPLLADAREALTALDGALGDTAWQ-AGWGEQIAAVQSRQMKEthrvyqasfqekgfipe 397
Cdd:COG0028 296 IIHIDI---DPAEIGknypvDLPIVGDAKAVLAALLEALEPRADDrAAWLARIAAWRAEYLAA----------------- 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 398 iddhldresvyrefRALTDSTLTQSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAA 477
Cdd:COG0028 356 --------------YAADDGPIKPQRVIAALREALPDDAIVVTDVGQHQMWAARYLRFRRPRRFLTSGGLGTMGYGLPAA 421
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 478 LGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ-MEHGMDSFGTEFRfrsaengqlng 556
Cdd:COG0028 422 IGAKLARPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNNGGLGMVRQWQeLFYGGRYSGTDLP----------- 490
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 655997487 557 glvPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVLP 605
Cdd:COG0028 491 ---NPDFAKLAEAFGAKGERVETPEELEAALEEALASDGPALIDVRVDP 536
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
5-603 |
5.25e-45 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 168.80 E-value: 5.25e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 5 RLTMAQALVKFLDNQYLEVdgetvkfvkgIFAIFGhGNVLGLGQALeQDSgELRLYQGRNEQGMAHAATGFARQSLRRQI 84
Cdd:PRK06048 7 KMTGARAIIKCLEKEGVEV----------IFGYPG-GAIIPVYDEL-YDS-DLRHILVRHEQAAAHAADGYARATGKVGV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 85 laCTSSVGPGAANMITAAATATANRIPLLLLPGDVfatrqPDPVLqqieqsydlsisTNDAFRA--VSKYWDRITRPEQL 162
Cdd:PRK06048 74 --CVATSGPGATNLVTGIATAYMDSVPIVALTGQV-----PRSMI------------GNDAFQEadITGITMPITKHNYL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 163 MSACINAMRVLTDP---AETG---AVTLALPQDVQGEA--WDYPQsffarRVHRLDRRP---ASQAQLNDAVAAIRASRK 231
Cdd:PRK06048 135 VQDAKDLPRIIKEAfhiASTGrpgPVLIDLPKDVTTAEidFDYPD-----KVELRGYKPtykGNPQQIKRAAELIMKAER 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 232 PLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTT 311
Cdd:PRK06048 210 PIIYAGGGVISSNASEELVELAETIPAPVTTTLMGIGAIPTEHPLSLGMLGMHGTKYANYAIQESDLIIAVGARFDDRVT 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 312 SSKWIFQhPDVRFLNINVSNFDAWK---LDgIPLLADAREALTALDGALGDTAWQAgWGEQIaavqsrqmKETHRVYQAS 388
Cdd:PRK06048 290 GKLASFA-PNAKIIHIDIDPAEISKnvkVD-VPIVGDAKQVLKSLIKYVQYCDRKE-WLDKI--------NQWKKEYPLK 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 389 FQEKgfipeiddhldresvyrefraltDSTLTQSNVLGILNETLPqEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYS 468
Cdd:PRK06048 359 YKER-----------------------EDVIKPQYVIEQIYELCP-DAIIVTEVGQHQMWAAQYFKYKYPRTFITSGGLG 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 469 CMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQmehgmdsfgtEFRFRS 548
Cdd:PRK06048 415 TMGYGFPAAIGAKVGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNGYLGMVRQWQ----------ELFYDK 484
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 655997487 549 AENGQLNGGlvPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK06048 485 RYSHTCIKG--SVDFVKLAEAYGALGLRVEKPSEVRPAIEEAVASDRPVVIDFIV 537
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
3-609 |
7.55e-45 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 168.35 E-value: 7.55e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 3 KLRLTMAQALVKFLDNQylevdgeTVKFVKGIFAifghGNVLGLGQALEQdSGELRLYQGRNEQGMAHAATGFARQSLRR 82
Cdd:PRK08155 10 RKRFTGAELIVRLLERQ-------GIRIVTGIPG----GAILPLYDALSQ-STQIRHILARHEQGAGFIAQGMARTTGKP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 83 QIlaCTSSVGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIEqSYDLSIStndafraVSKYWDRITRPEQL 162
Cdd:PRK08155 78 AV--CMACSGPGATNLVTAIADARLDSIPLVCITGQVPASMIGTDAFQEVD-TYGISIP-------ITKHNYLVRDIEEL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 163 MSACINAMRVLTDpAETGAVTLALPQDVQG-----EAWDYPQsffarrvhRLDRRPA-SQAQLNDAVAAIRASRKPLIIC 236
Cdd:PRK08155 148 PQVISDAFRIAQS-GRPGPVWIDIPKDVQTavielEALPAPA--------EKDAAPAfDEESIRDAAAMINAAKRPVLYL 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 237 GGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWI 316
Cdd:PRK08155 219 GGGVINSGAPARARELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGARSTNYILQEADLLIVLGARFDDRAIGKTEQ 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 317 FQhPDVRFLNINVsnfDAWKLDGI-----PLLADAREALTALDGALGDTAwQAGWGEQIAAVQsrqmkethrvyqasfQE 391
Cdd:PRK08155 299 FC-PNAKIIHVDI---DRAELGKIkqphvAIQADVDDVLAQLLPLVEAQP-RAEWHQLVADLQ---------------RE 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 392 KGF-IPEIDDHLdreSVYREFRA----LTDSTLTQSNVlgilnetlPQEAVIVAAAgsLPGDLQRVWRTRApnayhveyG 466
Cdd:PRK08155 359 FPCpIPKADDPL---SHYGLINAvaacVDDNAIITTDV--------GQHQMWTAQA--YPLNRPRQWLTSG--------G 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 467 YSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ-MEHGMDSFGTEFR 545
Cdd:PRK08155 418 LGTMGFGLPAAIGAALANPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIILMNNEALGLVHQQQsLFYGQRVFAATYP 497
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 546 FRsaengqlngglvpVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDI------KVLPktMV 609
Cdd:PRK08155 498 GK-------------INFMQIAAGFGLETCDLNNEADPQAALQEAINRPGPALIHVridaeeKVYP--MV 552
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
149-603 |
1.28e-44 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 167.07 E-value: 1.28e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 149 VSKYWDRITRPEQLMSACINAMRVLtDPAETGAVTLALPQDVQGEAWDYPQSffaRRVHRLDRRPASQAQLNDAVAAIRA 228
Cdd:PRK07524 125 VAAFSHTLMSAEDLPEVLARAFAVF-DSARPRPVHIEIPLDVLAAPADHLLP---APPTRPARPGPAPAALAQAAERLAA 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 229 SRKPLIICGGGVKysGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGvgeTGCLAA-NLLAKEADLVIGVGTRF- 306
Cdd:PRK07524 201 ARRPLILAGGGAL--AAAAALRALAERLDAPVALTINAKGLLPAGHPLLLGA---SQSLPAvRALIAEADVVLAVGTELg 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 307 -TDFTTSSKWIFQHPDvRFLNINVsnfDAWKLDG-----IPLLADAREALTALDGALGDTAWQAGWGEQIAAvqsrqmke 380
Cdd:PRK07524 276 eTDYDVYFDGGFPLPG-ELIRIDI---DPDQLARnyppaLALVGDARAALEALLARLPGQAAAADWGAARVA-------- 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 381 thRVYQASFQEkgfipeiddhldresvyrefraLTDSTLTQSNVLGILNETLPqEAVIV------AAAGSLPGDLQRVWR 454
Cdd:PRK07524 344 --ALRQALRAE----------------------WDPLTAAQVALLDTILAALP-DAIFVgdstqpVYAGNLYFDADAPRR 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 455 TrapnaYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQME 534
Cdd:PRK07524 399 W-----FNASTGYGTLGYGLPAAIGAALGAPERPVVCLVGDGGLQFTLPELASAVEADLPLIVLLWNNDGYGEIRRYMVA 473
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 655997487 535 HGMDSFGTEFRfrsaengqlngglvPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK07524 474 RDIEPVGVDPY--------------TPDFIALARAFGCAAERVADLEQLQAALRAAFARPGPTLIEVDQ 528
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
441-601 |
1.90e-44 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 155.44 E-value: 1.90e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 441 AAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLF 520
Cdd:pfam02775 1 DIGCHQMWAAQYYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 521 DNMANGCINNLQMEHGMDSFGTEFRFrsaengqlngGLVPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLID 600
Cdd:pfam02775 81 NNGGYGMTRGQQTPFGGGRYSGPSGK----------ILPPVDFAKLAEAYGAKGARVESPEELEEALKEALEHDGPALID 150
|
.
gi 655997487 601 I 601
Cdd:pfam02775 151 V 151
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
53-605 |
1.17e-43 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 164.66 E-value: 1.17e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 53 DSGELRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANRIPLLLLPGDV---FATRQpdpVL 129
Cdd:PRK08199 43 DETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFVTR--GPGATNASIGVHTAFQDSTPMILFVGQVardFRERE---AF 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 130 QQIEqsYDlsistnDAFRAVSKYWDRITRPEQLMSACINAMRVLTD--PaetGAVTLALPQDVQGEAWDYPqsfFARRVH 207
Cdd:PRK08199 118 QEID--YR------RMFGPMAKWVAEIDDAARIPELVSRAFHVATSgrP---GPVVLALPEDVLSETAEVP---DAPPYR 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 208 RLDRRPaSQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGetgcL 287
Cdd:PRK08199 184 RVAAAP-GAADLARLAELLARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACAFRRQDLFDNRHPNYAGDLG----L 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 288 AAN--LLA--KEADLVIGVGTRFTDFTTSS-----------KWIFQHPDVRFLNiNVSNFDawkldgIPLLADAREALTA 352
Cdd:PRK08199 259 GINpaLAAriREADLVLAVGTRLGEVTTQGytlldipvprqTLVHVHPDAEELG-RVYRPD------LAIVADPAAFAAA 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 353 LDG--ALGDTAWqAGWGEqiaavqsrqmkETHRVYQAsFQEKGFIPEiDDHLDResvyrefraltdstltqsnVLGILNE 430
Cdd:PRK08199 332 LAAlePPASPAW-AEWTA-----------AAHADYLA-WSAPLPGPG-AVQLGE-------------------VMAWLRE 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 431 TLPQEAVIVAAAGSLPGDLQRVWRTRApnaYHVEYGYSC--MGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTS 508
Cdd:PRK08199 379 RLPADAIITNGAGNYATWLHRFFRFRR---YRTQLAPTSgsMGYGLPAAIAAKLLFPERTVVAFAGDGCFLMNGQELATA 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 509 IQEGAKVNVLLFDNmangcinnlqmehGMdsFGT-----EFRFrsaeNGQLNG-GLVPVDFAAIAAGYGCKTWRVTTLDE 582
Cdd:PRK08199 456 VQYGLPIIVIVVNN-------------GM--YGTirmhqEREY----PGRVSGtDLTNPDFAALARAYGGHGETVERTED 516
|
570 580
....*....|....*....|...
gi 655997487 583 LKIALEAAQRETVSTLIDIKVLP 605
Cdd:PRK08199 517 FAPAFERALASGKPALIEIRIDP 539
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
9-610 |
1.17e-43 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 165.31 E-value: 1.17e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 9 AQALVKFLDNQylevdgetvkfvkGIFAIFGH--GNVLGLGQALeQDSgELRLYQGRNEQGMAHAATGFARQSLRRQIla 86
Cdd:PRK06276 4 AEAIIKALEAE-------------GVKIIFGYpgGALLPFYDAL-YDS-DLIHILTRHEQAAAHAADGYARASGKVGV-- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 87 CTSSVGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIEQsydLSIstndaFRAVSKYWDRITRPEQLMSAC 166
Cdd:PRK06276 67 CVATSGPGATNLVTGIATAYADSSPVIALTGQVPTKLIGNDAFQEIDA---LGI-----FMPITKHNFQIKKPEEIPEIF 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 167 INAMRVltdpAETG---AVTLALPQDVQGEAWDYPQSFFARRVHRLDRRPASQA---QLNDAVAAIRASRKPLIICGGGV 240
Cdd:PRK06276 139 RAAFEI----AKTGrpgPVHIDLPKDVQEGELDLEKYPIPAKIDLPGYKPTTFGhplQIKKAAELIAEAERPVILAGGGV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 241 KYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFQhP 320
Cdd:PRK06276 215 IISGASEELIELSELVKIPVCTTLMGKGAFPEDHPLALGMVGMHGTKAANYSVTESDVLIAIGCRFSDRTTGDISSFA-P 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 321 DVRFLNINVSNFDAWK---LDgIPLLADA----REALTALDGALGDTAWQagWGEQIAAVQSRQMKEThrvyqaSFQEKG 393
Cdd:PRK06276 294 NAKIIHIDIDPAEIGKnvrVD-VPIVGDAknvlRDLLAELMKKEIKNKSE--WLERVKKLKKESIPRM------DFDDKP 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 394 FIPeiddhldrESVYREFRALTDSTLTQSNVlgILNETLPQEAVIVAaagslpgdlqRVWRTRAPNAYHVEYGYSCMGYE 473
Cdd:PRK06276 365 IKP--------QRVIKELMEVLREIDPSKNT--IITTDVGQNQMWMA----------HFFKTSAPRSFISSGGLGTMGFG 424
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 474 VSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMehgmdsfgtefRFRSAENGQ 553
Cdd:PRK06276 425 FPAAIGAKVAKPDANVIAITGDGGFLMNSQELATIAEYDIPVVICIFDNRTLGMVYQWQN-----------LYYGKRQSE 493
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 655997487 554 LNGGLVPvDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVLPKTMVH 610
Cdd:PRK06276 494 VHLGETP-DFVKLAESYGVKADRVEKPDEIKEALKEAIKSGEPYLLDIIIDPAEALP 549
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
31-603 |
3.12e-43 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 163.86 E-value: 3.12e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 31 VKGIFAIFGHGNvLGLGQALEQD--SGELRLYQGRNEQGMAHAATGFARQSLRRQIlaCTSSVGPGAANMITAAATATAN 108
Cdd:PRK06456 17 VKVIFGIPGLSN-MQIYDAFVEDlaNGELRHVLMRHEQAAAHAADGYARASGVPGV--CTATSGPGTTNLVTGLITAYWD 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 109 RIPLLLLPGDVfatrqPDPVLQQIE-QSYDlsisTNDAFRAVSKYWDRITRPEQLMSACINAMRVLTDpAETGAVTLALP 187
Cdd:PRK06456 94 SSPVIAITGQV-----PRSVMGKMAfQEAD----AMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATT-GRPGPVVIDIP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 188 QDVQGEAWD---YPQSFFARRvHRLDRRPASQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQ 264
Cdd:PRK06456 164 RDIFYEKMEeikWPEKPLVKG-YRDFPTRIDRLALKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHIPIVSTF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 265 AGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFQHPDVRFLNINVSNFD---AWKLDgIP 341
Cdd:PRK06456 243 PGKTAIPHDHPLYFGPMGYYGRAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDgekAIKVD-VG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 342 LLADAREALTALDGALGDTAWQAGWGEQIaavqsRQMKEtHRVYQASFqekgfipeiddhldresVYREfralTDSTLTQ 421
Cdd:PRK06456 322 IYGNAKIILRELIKAITELGQKRDRSAWL-----KRVKE-YKEYYSQF-----------------YYTE----ENGKLKP 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 422 SNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMML 501
Cdd:PRK06456 375 WKIMKTIRQALPRDAIVTTGVGQHQMWAEVFWEVLEPRTFLTSSGMGTMGFGLPAAMGAKLARPDKVVVDLDGDGSFLMT 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 502 HSELVTSIQEGAKVNVLLFDNMANGCINNLQmehgmDSFgtefrfrsaENGQLNG---GLVPvDFAAIAAGYGCKTWRVT 578
Cdd:PRK06456 455 GTNLATAVDEHIPVISVIFDNRTLGLVRQVQ-----DLF---------FGKRIVGvdyGPSP-DFVKLAEAFGALGFNVT 519
|
570 580
....*....|....*....|....*
gi 655997487 579 TLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK06456 520 TYEDIEKSLKSAIKEDIPAVIRVPV 544
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
63-605 |
3.97e-43 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 163.78 E-value: 3.97e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 63 RNEQGMAHAATGFARQSlrRQILACTSSVGPGAANMITAAATATANRIPLLLLPGDVfATRQPDP-VLQQIEQSydlsis 141
Cdd:PRK06112 56 RTENAGGAMADGYARVS--GKVAVVTAQNGPAATLLVAPLAEALKASVPIVALVQDV-NRDQTDRnAFQELDHI------ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 142 tnDAFRAVSKYWDRITRPEQLMSACINAMRVLTDpAETGAVTLALPQDVQGEAWDYPQSFFARRVHR--LDRRPASQAQL 219
Cdd:PRK06112 127 --ALFQSCTKWVRRVTVAERIDDYVDQAFTAATS-GRPGPVVLLLPADLLTAAAAAPAAPRSNSLGHfpLDRTVPAPQRL 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 220 NDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGEtgCLAANLLAK----- 294
Cdd:PRK06112 204 AEAASLLAQAQRPVVVAGGGVHISGASAALAALQSLAGLPVATTNMGKGAVDETHPLSLGVVGS--LMGPRSPGRhlrdl 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 295 --EADLVIGVGTRFTDFTTSSkWIFQHPDVRFLNINVS------NFDAWKLDGipllaDAREALTALDGAL------GDT 360
Cdd:PRK06112 282 vrEADVVLLVGTRTNQNGTDS-WSLYPEQAQYIHIDVDgeevgrNYEALRLVG-----DARLTLAALTDALrgrdlaARA 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 361 AWQAGWGEQIAAVQSRQMKETHRVYQASF---QEKGFIPEIDDHLDRESVYrefraLTDSTLTQSNVLGILNETlpqeav 437
Cdd:PRK06112 356 GRRAALEPAIAAGREAHREDSAPVALSDAspiRPERIMAELQAVLTGDTIV-----VADASYSSIWVANFLTAR------ 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 438 ivaAAGslpgdlQRVWRTRapnayhveyGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNV 517
Cdd:PRK06112 425 ---RAG------MRFLTPR---------GLAGLGWGVPMAIGAKVARPGAPVICLVGDGGFAHVWAELETARRMGVPVTI 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 518 LLFDNMangcINNLQMEHGMDSFGTefrFRSAENgqlnggLVPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVST 597
Cdd:PRK06112 487 VVLNNG----ILGFQKHAETVKFGT---HTDACH------FAAVDHAAIARACGCDGVRVEDPAELAQALAAAMAAPGPT 553
|
....*...
gi 655997487 598 LIDIKVLP 605
Cdd:PRK06112 554 LIEVITDP 561
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
6-603 |
7.14e-43 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 162.30 E-value: 7.14e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 6 LTMAQALVKFLDNqylevdgETVKFvkgIFAIFGHGNvLGLGQALEQDSgeLRLYQGRNEQGMAHAATGFARqsLRRQIL 85
Cdd:PRK08322 1 MKAADLFVKCLEN-------EGVEY---IFGIPGEEN-LDLLEALRDSS--IKLILTRHEQGAAFMAATYGR--LTGKAG 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 86 ACTSSVGPGAANMITAAATATANRIPLLLLPGDVfatrqpdPVL---QQIEQSYDLSistnDAFRAVSKYWDRITRPEQL 162
Cdd:PRK08322 66 VCLSTLGPGATNLVTGVAYAQLGGMPMVAITGQK-------PIKrskQGSFQIVDVV----AMMAPLTKWTRQIVSPDNI 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 163 MSACINAMRVltdpAET---GAVTLALPQDVQGEawDYPQSFFARRVHRldrRP-ASQAQLNDAVAAIRASRKPLIICGG 238
Cdd:PRK08322 135 PEVVREAFRL----AEEerpGAVHLELPEDIAAE--ETDGKPLPRSYSR---RPyASPKAIERAAEAIQAAKNPLILIGA 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 239 GVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGetgcLAA----NLLAKEADLVIGVGTRFTDFtTSSK 314
Cdd:PRK08322 206 GANRKTASKALTEFVDKTGIPFFTTQMGKGVIPETHPLSLGTAG----LSQgdyvHCAIEHADLIINVGHDVIEK-PPFF 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 315 WifqHPDVRFLNINVsNFDAWKLDG--IPLL---ADAREALTALDGALGDtawQAGWGEQIAAvQSRQMKETHrvYQASF 389
Cdd:PRK08322 281 M---NPNGDKKVIHI-NFLPAEVDPvyFPQVevvGDIANSLWQLKERLAD---QPHWDFPRFL-KIREAIEAH--LEEGA 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 390 QEKGF--IPEiddhldresvyrefRALTDstltqsnvlgiLNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGY 467
Cdd:PRK08322 351 DDDRFpmKPQ--------------RIVAD-----------LRKVMPDDDIVILDNGAYKIWFARNYRAYEPNTCLLDNAL 405
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 468 SCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTEFrfr 547
Cdd:PRK08322 406 ATMGAGLPSAIAAKLVHPDRKVLAVCGDGGFMMNSQELETAVRLGLPLVVLILNDNAYGMIRWKQENMGFEDFGLDF--- 482
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 655997487 548 saENgqlngglvPvDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK08322 483 --GN--------P-DFVKYAESYGAKGYRVESADDLLPTLEEALAQPGVHVIDCPV 527
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
33-588 |
3.68e-42 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 160.76 E-value: 3.68e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 33 GIFAIFGH--GNVLGLGQALEQDSGeLRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANRI 110
Cdd:PRK07282 24 GVDTIFGYpgGAVLPLYDAIYNFEG-IRHILARHEQGALHEAEGYAKSTGKLGVAVVTS--GPGATNAITGIADAMSDSV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 111 PLLLLPGDVfATRqpdpvlqqieqsydlSIStNDAFR---------AVSKYWDRITRPEQLMSACINAMRVLTDpAETGA 181
Cdd:PRK07282 101 PLLVFTGQV-ARA---------------GIG-KDAFQeadivgitmPITKYNYQIRETADIPRIITEAVHIATT-GRPGP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 182 VTLALPQDVQGEAWDYpqsFFARRVHRLDRRP---ASQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRI 258
Cdd:PRK07282 163 VVIDLPKDVSALETDF---IYDPEVNLPSYQPtlePNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 259 PFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIF-QHPDVRFLNINVSNFDAWKL 337
Cdd:PRK07282 240 PVVTTLLGQGTIATSHPLFLGMGGMHGSYAANIAMTEADFMINIGSRFDDRLTGNPKTFaKNAKVAHIDIDPAEIGKIIK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 338 DGIPLLADAREALTALdgaLGDTAWQAGWGEQIAAVQsrQMKETHRVYQasFQEKGFIPEiddhldresvyrefraltds 417
Cdd:PRK07282 320 TDIPVVGDAKKALQML---LAEPTVHNNTEKWIEKVT--KDKNRVRSYD--KKERVVQPQ-------------------- 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 418 tltqsNVLGILNETLPQEAVIVAAAGSlpgdlQRVWRTR---APNAYHV--EYGYSCMGYEVSAALGVKLAEPQREVYAM 492
Cdd:PRK07282 373 -----AVIERIGELTNGDAIVVTDVGQ-----HQMWAAQyypYQNERQLvtSGGLGTMGFGIPAAIGAKIANPDKEVILF 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 493 VGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQmehgmDSFGTEFRFRSAENGQLNgglvpvdFAAIAAGYGC 572
Cdd:PRK07282 443 VGDGGFQMTNQELAILNIYKVPIKVVMLNNHSLGMVRQWQ-----ESFYEGRTSESVFDTLPD-------FQLMAQAYGI 510
|
570 580
....*....|....*....|
gi 655997487 573 KTWRV----TTLDELKIALE 588
Cdd:PRK07282 511 KHYKFdnpeTLAQDLEVITE 530
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
33-589 |
1.07e-41 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 159.36 E-value: 1.07e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 33 GIFAIFGH--GNVLGLGQALeQDSGeLRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANRI 110
Cdd:PRK06725 29 GVTTVFGYpgGAILPVYDAL-YESG-LKHILTRHEQAAIHAAEGYARASGKVGVVFATS--GPGATNLVTGLADAYMDSI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 111 PLLLLPGDVfAT--------RQPD------PVLQ---QIEQSYDLSISTNDAFravskYWDRITRPeqlmsacinamrvl 173
Cdd:PRK06725 105 PLVVITGQV-ATpligkdgfQEADvvgitvPVTKhnyQVRDVNQLSRIVQEAF-----YIAESGRP-------------- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 174 tdpaetGAVTLALPQDVQGEAwdyPQSFFARRV----HRLDRRPASQaQLNDAVAAIRASRKPLIICGGGVKYSGAGEAL 249
Cdd:PRK06725 165 ------GPVLIDIPKDVQNEK---VTSFYNEVVeipgYKPEPRPDSM-KLREVAKAISKAKRPLLYIGGGVIHSGGSEEL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 250 AHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFQ-HPDVRFLNIN 328
Cdd:PRK06725 235 IEFARENRIPVVSTLMGLGAYPPGDPLFLGMLGMHGTYAANMAVTECDLLLALGVRFDDRVTGKLELFSpHSKKVHIDID 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 329 VSNFDAWKLDGIPLLADAREALTALDGALGDTAWQAgWGEQIaavqsRQMKEThrvYQASFQEKgfipeiddhldresvy 408
Cdd:PRK06725 315 PSEFHKNVAVEYPVVGDVKKALHMLLHMSIHTQTDE-WLQKV-----KTWKEE---YPLSYKQK---------------- 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 409 refraltDSTLTQSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQRE 488
Cdd:PRK06725 370 -------ESELKPQHVINLVSELTNGEAIVTTEVGQHQMWAAHFYKAKNPRTFLTSGGLGTMGFGFPAAIGAQLAKEEEL 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 489 VYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQmehgmdSFGTEFRFRSAENGQlngglvPvDFAAIAA 568
Cdd:PRK06725 443 VICIAGDASFQMNIQELQTIAENNIPVKVFIINNKFLGMVRQWQ------EMFYENRLSESKIGS------P-DFVKVAE 509
|
570 580
....*....|....*....|..
gi 655997487 569 GYGCKTWRVTTLDELK-IALEA 589
Cdd:PRK06725 510 AYGVKGLRATNSTEAKqVMLEA 531
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
219-353 |
1.21e-41 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 147.33 E-value: 1.21e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 219 LNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADL 298
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALEEADL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 299 VIGVGTRFTDFTTSSKWIFQHPDVRFLNINVsnfDAWKLD-----GIPLLADAREALTAL 353
Cdd:pfam00205 81 VLAVGARFDDIRTTGKLPEFAPDAKIIHIDI---DPAEIGknypvDVPIVGDAKETLEAL 137
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
63-617 |
1.25e-41 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 159.11 E-value: 1.25e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 63 RNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANRIPLLLLPGDVfatrqpdpvlqqieqsyDLSIST 142
Cdd:PRK08527 48 RHEQAAVHAADGYARASGKVGVAIVTS--GPGFTNAVTGLATAYMDSIPLVLISGQV-----------------PNSLIG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 143 NDAFR---AVSkywdrITRP---EQLMSACINAM-RVLTDP---AET---GAVTLALPQDVQGEA--WDYPQSffarrVH 207
Cdd:PRK08527 109 TDAFQeidAVG-----ISRPcvkHNYLVKSIEELpRILKEAfyiARSgrpGPVHIDIPKDVTATLgeFEYPKE-----IS 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 208 RLDRRP---ASQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGET 284
Cdd:PRK08527 179 LKTYKPtykGNSRQIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTGIPAVETLMARGVLRSDDPLLLGMLGMH 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 285 GCLAANLLAKEADLVIGVGTRFTDFTTSSKWIF-QHPDVRFLNINVSNFDAWKLDGIPLLADAREALTALDGALGDTAWQ 363
Cdd:PRK08527 259 GSYAANMAMSECDLLISLGARFDDRVTGKLSEFaKHAKIIHVDIDPSSISKIVNADYPIVGDLKNVLKEMLEELKEENPT 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 364 --AGWGEQIaavqsRQMKETHRV-YQASfqekgfipeiDDHLDRESVYREfraltdstltqsnvlgiLNETLPQEAVIVA 440
Cdd:PRK08527 339 tyKEWREIL-----KRYNELHPLsYEDS----------DEVLKPQWVIER-----------------VGELLGDDAIIST 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 441 --------AAGSLPGDLQRVWRTRApnayhveyGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEG 512
Cdd:PRK08527 387 dvgqhqmwVAQFYPFNYPRQLATSG--------GLGTMGYGLPAALGAKLAVPDKVVINFTGDGSILMNIQELMTAVEYK 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 513 AKV-NVLLFDNMangcinnLQMEHGMDSFGTEFRFrsaenGQLNGGLVPvDFAAIAAGYGCKTWRVTTLDELKIALEAAQ 591
Cdd:PRK08527 459 IPViNIILNNNF-------LGMVRQWQTFFYEERY-----SETDLSTQP-DFVKLAESFGGIGFRVTTKEEFDKALKEAL 525
|
570 580 590
....*....|....*....|....*....|..
gi 655997487 592 RETVSTLIDIK------VLPktMVHKYGSWWN 617
Cdd:PRK08527 526 ESDKVALIDVKidrfenVLP--MVPAGGALYN 555
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
31-603 |
5.31e-41 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 157.10 E-value: 5.31e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 31 VKGIFAIFGhGNVLGLGQALEQDSGELRLYQGRNEQGMAHAATGFARQSLRrqILACTSSVGPGAANMITAAATATANRI 110
Cdd:PRK08266 19 VDTVFGLPG-AQLYWLFDALYKAGDRIRVIHTRHEQAAGYMAFGYARSTGR--PGVCSVVPGPGVLNAGAALLTAYGCNS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 111 PLLLLPGDVFAtrqpdpvlQQIEQSYDLSISTND---AFRAVSKYWDRITRPEQ---LMSACINAMRvltdPAETGAVTL 184
Cdd:PRK08266 96 PVLCLTGQIPS--------ALIGKGRGHLHEMPDqlaTLRSFTKWAERIEHPSEapaLVAEAFQQML----SGRPRPVAL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 185 ALPQDVQGEAWDYPQSFFARRVhrldRRPASQAQLNDAVAA-IRASRKPLIICGGGVkySGAGEALAHFAERYRIPFAET 263
Cdd:PRK08266 164 EMPWDVFGQRAPVAAAPPLRPA----PPPAPDPDAIAAAAAlIAAAKNPMIFVGGGA--AGAGEEIRELAEMLQAPVVAF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 264 QAGKGTLISSHPynvggVGETgCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFQHPDVRFLNINVSNFDAWKLDgIPLL 343
Cdd:PRK08266 238 RSGRGIVSDRHP-----LGLN-FAAAYELWPQTDVVIGIGSRLELPTFRWPWRPDGLKVIRIDIDPTEMRRLKPD-VAIV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 344 ADAREALTALdgalgdtawqagwgeqIAAVQSRQMKEThrvyqasfqekgfipeiddhlDRESVYREFRALTDSTLT--- 420
Cdd:PRK08266 311 ADAKAGTAAL----------------LDALSKAGSKRP---------------------SRRAELRELKAAARQRIQavq 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 421 -QSNVLGILNETLPQEAVIV--------AAAGSLPgdlqrVWrtrAPNAYhVEYGYS-CMGYEVSAALGVKLAEPQREVY 490
Cdd:PRK08266 354 pQASYLRAIREALPDDGIFVdelsqvgfASWFAFP-----VY---APRTF-VTCGYQgTLGYGFPTALGAKVANPDRPVV 424
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 491 AMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEhgmdsfgtefRFRSAEngqLNGGLVPVDFAAIAAGY 570
Cdd:PRK08266 425 SITGDGGFMFGVQELATAVQHNIGVVTVVFNNNAYGNVRRDQKR----------RFGGRV---VASDLVNPDFVKLAESF 491
|
570 580 590
....*....|....*....|....*....|...
gi 655997487 571 GCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK08266 492 GVAAFRVDSPEELRAALEAALAHGGPVLIEVPV 524
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
5-609 |
1.50e-39 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 153.98 E-value: 1.50e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 5 RLTMAQALVKFLDnqylEVDGETVkfvkgiFAIFGhGNVLGLGQALeQDSGELRLYQGRNEQGMAHAATGFARQSLRRQI 84
Cdd:PRK07789 30 RMTGAQAVVRSLE----ELGVDVV------FGIPG-GAILPVYDPL-FDSTKVRHVLVRHEQGAGHAAEGYAQATGRVGV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 85 LACTSsvGPGAANMITAAATATANRIPLLLLPGDVFATrqpdpvlqqieqsydlSISTnDAFR---------AVSKYWDR 155
Cdd:PRK07789 98 CMATS--GPGATNLVTPIADANMDSVPVVAITGQVGRG----------------LIGT-DAFQeadivgitmPITKHNFL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 156 ITRPEQLMSACINAMRVltdpAETG---AVTLALPQDVQGEAWDY--PQsffarrvhRLD---RRPASQA---QLNDAVA 224
Cdd:PRK07789 159 VTDADDIPRVIAEAFHI----ASTGrpgPVLVDIPKDALQAQTTFswPP--------RMDlpgYRPVTKPhgkQIREAAK 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 225 AIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGT 304
Cdd:PRK07789 227 LIAAARRPVLYVGGGVIRAEASAELRELAELTGIPVVTTLMARGAFPDSHPQHLGMPGMHGTVAAVAALQRSDLLIALGA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 305 RFTDFTTSSKWIFQhPDVRFLNINV------SNFDAwkldGIPLLADAREALTAL------DGALGDTAWQAGWGEQIaa 372
Cdd:PRK07789 307 RFDDRVTGKLDSFA-PDAKVIHADIdpaeigKNRHA----DVPIVGDVKEVIAELiaalraEHAAGGKPDLTAWWAYL-- 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 373 vqsRQMKEThrvYQASFQEKgfipeiddhldresvyrefralTDSTLTQSNVLGILNETLPQEAVIVAAAGSlpgdlQRV 452
Cdd:PRK07789 380 ---DGWRET---YPLGYDEP----------------------SDGSLAPQYVIERLGEIAGPDAIYVAGVGQ-----HQM 426
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 453 WRTRA-----PNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGC 527
Cdd:PRK07789 427 WAAQFidyekPRTWLNSGGLGTMGYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQELATCAIEGIPIKVALINNGNLGM 506
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 528 INNLQmehgmdsfgTEFRFRSAENGQLN--GGLVPvDFAAIAAGYGCKTWRVTTLDELKIALEAAQ----RETVstlIDI 601
Cdd:PRK07789 507 VRQWQ---------TLFYEERYSNTDLHthSHRIP-DFVKLAEAYGCVGLRCEREEDVDAVIEKARaindRPVV---IDF 573
|
....*...
gi 655997487 602 KVLPKTMV 609
Cdd:PRK07789 574 VVGKDAMV 581
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
49-605 |
2.96e-38 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 149.77 E-value: 2.96e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 49 ALEQDSGELRLYQGRNEQGMAHAATGFARqsLRRQILACTSSVGPGAANMITAAATATANRIPLLLLPGDVFATrqpdpv 128
Cdd:PRK08611 36 ALRKEQDKIKFIQVRHEEVAALAAAAYAK--LTGKIGVCLSIGGPGAIHLLNGLYDAKMDHVPVLALAGQVTSD------ 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 129 lqQIEQSYDLSISTNDAFRAVSKYWDRITRPEQLMSACINAMRvlTDPAETGAVTLALPQDV--QGEAWDY--PQSFFAR 204
Cdd:PRK08611 108 --LLGTDFFQEVNLEKMFEDVAVYNHQIMSAENLPEIVNQAIR--TAYEKKGVAVLTIPDDLpaQKIKDTTnkTVDTFRP 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 205 RVHRLDRRpasqaQLNDAVAAIRASRKPLIICGGGVKysGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGET 284
Cdd:PRK08611 184 TVPSPKPK-----DIKKAAKLINKAKKPVILAGLGAK--HAKEELLAFAEKAKIPIIHTLPAKGIIPDDHPYSLGNLGKI 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 285 GCLAANLLAKEADLVIGVGTRF--TDF---TTSSKWIFQHPDV---RFlNINVSnfdawkldgipLLADAREALTALDga 356
Cdd:PRK08611 257 GTKPAYEAMQEADLLIMVGTNYpyVDYlpkKAKAIQIDTDPANigkRY-PVNVG-----------LVGDAKKALHQLT-- 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 357 lgdtawqagwgEQIAAVQSRQMKETHRVYQASFqekgfipeiDDHLDREsvyrefRALTDSTLTQSNVLGILNETLPQEA 436
Cdd:PRK08611 323 -----------ENIKHVEDRRFLEACQENMAKW---------WKWMEED------ENNASTPIKPERVMAAIQKIADDDA 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 437 VIVAAAGSLPgdlqrVWRTR-----APNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQE 511
Cdd:PRK08611 377 VLSVDVGTVT-----VWSARylnlgTNQKFIISSWLGTMGCGLPGAIAAKIAFPDRQAIAICGDGGFSMVMQDFVTAVKY 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 512 GAKVNVLLFDNmangciNNLQMehgmdsfgTEFRFRSAenGQLNGG--LVPVDFAAIAAGYGCKTWRVTTLDELKIALEA 589
Cdd:PRK08611 452 KLPIVVVVLNN------QQLAF--------IKYEQQAA--GELEYAidLSDMDYAKFAEACGGKGYRVEKAEELDPAFEE 515
|
570
....*....|....*.
gi 655997487 590 AQRETVSTLIDIKVLP 605
Cdd:PRK08611 516 ALAQDKPVIIDVYVDP 531
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
33-603 |
1.52e-37 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 147.89 E-value: 1.52e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 33 GIFAIFGH--GNVLGLGQAL---EQDsGELRLYQGRNEQGMAHAATGFARQSlrRQILACTSSVGPGAANMITAAATATA 107
Cdd:PRK07418 33 GVKHIFGYpgGAILPIYDELykaEAE-GWLKHILVRHEQGAAHAADGYARAT--GKVGVCFGTSGPGATNLVTGIATAQM 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 108 NRIPLLLLPGDVfatrqPDPvlqqieqsydlSISTnDAFRAVSKYwdRITRPeqlmsaCINAMRVLTDPAET-------- 179
Cdd:PRK07418 110 DSVPMVVITGQV-----PRP-----------AIGT-DAFQETDIF--GITLP------IVKHSYVVRDPSDMarivaeaf 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 180 --------GAVTLALPQDVQGEAWDY---------PQSFfaRRVHRLDRRpasqaQLNDAVAAIRASRKPLIICGGGVKY 242
Cdd:PRK07418 165 hiassgrpGPVLIDIPKDVGQEEFDYvpvepgsvkPPGY--RPTVKGNPR-----QINAALKLIEEAERPLLYVGGGAIS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 243 SGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTD--------FTTSSK 314
Cdd:PRK07418 238 AGAHAELKELAERFQIPVTTTLMGKGAFDEHHPLSVGMLGMHGTAYANFAVTECDLLIAVGARFDDrvtgkldeFASRAK 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 315 WIfqHPDVRFLNINVSnfdawKLDGIPLLADAREALTALDGALGDTAWQ---AGWGEQIAavqsrQMKETHRVYqasfqe 391
Cdd:PRK07418 318 VI--HIDIDPAEVGKN-----RRPDVPIVGDVRKVLVKLLERSLEPTTPprtQAWLERIN-----RWKQDYPLV------ 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 392 kgfIPEIDDhldreSVYrefraltdstltqsnvlgilnetlPQEaVIVAAagslpgdlqrvwRTRAPNAY-------H-- 462
Cdd:PRK07418 380 ---VPPYEG-----EIY------------------------PQE-VLLAV------------RDLAPDAYyttdvgqHqm 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 463 --VEY------------GYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCI 528
Cdd:PRK07418 415 waAQFlrngprrwissaGLGTMGFGMPAAMGVKVALPDEEVICIAGDASFLMNIQELGTLAQYGINVKTVIINNGWQGMV 494
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 655997487 529 NNLQmehgmDSFGTEfRFrSAENgQLNGglVPvDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK07418 495 RQWQ-----ESFYGE-RY-SASN-MEPG--MP-DFVKLAEAFGVKGMVISERDQLKDAIAEALAHDGPVLIDVHV 558
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
63-522 |
2.98e-37 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 146.18 E-value: 2.98e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 63 RNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANRIPLLLLPGDVfatrqPDPVlqqieqsydlsIST 142
Cdd:PRK08978 45 RHEQGAAMAAIGYARATGKVGVCIATS--GPGATNLITGLADALLDSVPVVAITGQV-----SSPL-----------IGT 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 143 nDAFR---------AVSKYWDRITRPEQLMSACINAMRVltdpAET---GAVTLALPQDVQGEAWDYPQSFFARrvhrLD 210
Cdd:PRK08978 107 -DAFQeidvlglslACTKHSFLVQSLEELPEIMAEAFEI----ASSgrpGPVLVDIPKDIQLAEGELEPHLTTV----EN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 211 RRPASQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAAN 290
Cdd:PRK08978 178 EPAFPAAELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVATLKGLGAVEADHPYYLGMLGMHGTKAAN 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 291 LLAKEADLVIGVGTRFTDFTTSSKWIF-QHPDVRFLNINVSNFDAWKLDGIPLLADAREALTALDGALGDTAWQAgwgeq 369
Cdd:PRK08978 258 LAVQECDLLIAVGARFDDRVTGKLNTFaPHAKVIHLDIDPAEINKLRQAHVALQGDLNALLPALQQPLNIDAWRQ----- 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 370 iaavQSRQMKETHrvyQASFQEKGfipeiddhldrESVYREFraltdstltqsnVLGILNETLPQEAVIVAAAGSlpgdl 449
Cdd:PRK08978 333 ----HCAQLRAEH---AWRYDHPG-----------EAIYAPA------------LLKQLSDRKPADTVVTTDVGQ----- 377
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655997487 450 QRVW-----RTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDN 522
Cdd:PRK08978 378 HQMWvaqhmRFTRPENFITSSGLGTMGFGLPAAIGAQVARPDDTVICVSGDGSFMMNVQELGTIKRKQLPVKIVLLDN 455
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
32-590 |
2.55e-36 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 143.81 E-value: 2.55e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 32 KGIFAIFGH--GNVLGLGQALEQDSGeLRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANR 109
Cdd:PRK08979 17 EGVKHIFGYpgGSVLDIYDALHEKSG-IEHILVRHEQAAVHMADGYARATGKVGVVLVTS--GPGATNTITGIATAYMDS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 110 IPLLLLPGDVfatrqPDpvlqqieqsydlSISTNDAF---------RAVSKYWDRITRPEQLMSACINAMRVLTDpAETG 180
Cdd:PRK08979 94 IPMVVLSGQV-----PS------------NLIGNDAFqecdmigisRPVVKHSFLVKDAEDIPEIIKKAFYIAST-GRPG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 181 AVTLALPQDVQGEA----WDYPQSFFARRVHrldrrPASQA---QLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFA 253
Cdd:PRK08979 156 PVVIDLPKDCLNPAilhpYEYPESIKMRSYN-----PTTSGhkgQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 254 ERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSS--KWIfqhPDVRFLNINV-- 329
Cdd:PRK08979 231 EKLNLPVVSTLMGLGAFPGTHKNSLGMLGMHGRYEANMAMHNADLIFGIGVRFDDRTTNNleKYC---PNATILHIDIdp 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 330 -SNFDAWKLDgIPLLADAREALTAL------DGALGDTAWQAGWGEQIAAVQSRQM----KETHRVyqasfQEKGFIpei 398
Cdd:PRK08979 308 sSISKTVRVD-IPIVGSADKVLDSMlalldeSGETNDEAAIASWWNEIEVWRSRNClaydKSSERI-----KPQQVI--- 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 399 ddhldrESVYRefraLTDSTLTQSNVLGilnetlpQEAVIvaAAGSLPGDLQRVWRTRApnayhveyGYSCMGYEVSAAL 478
Cdd:PRK08979 379 ------ETLYK----LTNGDAYVASDVG-------QHQMF--AALYYPFDKPRRWINSG--------GLGTMGFGLPAAM 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 479 GVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ-----MEHG---MDSfgtefrfrsae 550
Cdd:PRK08979 432 GVKFAMPDETVVCVTGDGSIQMNIQELSTALQYDIPVKIINLNNRFLGMVKQWQdmiyqGRHShsyMDS----------- 500
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 655997487 551 ngqlngglVPvDFAAIAAGYGCKTWRVTTLDELKIALEAA 590
Cdd:PRK08979 501 --------VP-DFAKIAEAYGHVGIRISDPDELESGLEKA 531
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
3-609 |
4.06e-36 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 143.36 E-value: 4.06e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 3 KLRLTMAQALVKFLDNQYLEVdgetvkfvkgifaIFGH--GNVLGLGQALeQDSGELRLYQgRNEQGMAHAATGFARQSL 80
Cdd:PRK07710 13 EKLMTGAQMLIEALEKEGVEV-------------IFGYpgGAVLPLYDAL-YDCGIPHILT-RHEQGAIHAAEGYARISG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 81 RRQILACTSsvGPGAANMITAAATATANRIPLLLLPGDVfATrqpdpvlqqieqsydlSISTNDAFR---------AVSK 151
Cdd:PRK07710 78 KPGVVIATS--GPGATNVVTGLADAMIDSLPLVVFTGQV-AT----------------SVIGSDAFQeadimgitmPVTK 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 152 YWDRITRPEQLMSACINAMRVLTDpAETGAVTLALPQDV---QGEaWDYPQSffarrVHRLDRRPASQA---QLNDAVAA 225
Cdd:PRK07710 139 HNYQVRKASDLPRIIKEAFHIATT-GRPGPVLIDIPKDMvveEGE-FCYDVQ-----MDLPGYQPNYEPnllQIRKLVQA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 226 IRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTR 305
Cdd:PRK07710 212 VSVAKKPVILAGAGVLHAKASKELTSYAEQQEIPVVHTLLGLGGFPADHPLFLGMAGMHGTYTANMALYECDLLINIGAR 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 306 FTDFTTSS-KWIFQHPDVRFLNINVSNFDAWKLDGIPLLADAREALTAL---DGALGDT-AWQAgwgeqiaavqsrQMKE 380
Cdd:PRK07710 292 FDDRVTGNlAYFAKEATVAHIDIDPAEIGKNVPTEIPIVADAKQALQVLlqqEGKKENHhEWLS------------LLKN 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 381 THRVYQASFQ--EKGFIPEiddhldresvyrefraltdstltqsNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAP 458
Cdd:PRK07710 360 WKEKYPLSYKrnSESIKPQ-------------------------KAIEMLYEITKGEAIVTTDVGQHQMWAAQYYPFKTP 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 459 NAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQmehgmD 538
Cdd:PRK07710 415 DKWVTSGGLGTMGFGLPAAIGAQLAKPDETVVAIVGDGGFQMTLQELSVIKELSLPVKVVILNNEALGMVRQWQ-----E 489
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655997487 539 SFGTEFRFRSAENGQlngglvPvDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVLPKTMV 609
Cdd:PRK07710 490 EFYNQRYSHSLLSCQ------P-DFVKLAEAYGIKGVRIDDELEAKEQLQHAIELQEPVVIDCRVLQSEKV 553
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
424-603 |
5.19e-36 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 133.15 E-value: 5.19e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 424 VLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHS 503
Cdd:cd00568 2 VLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRPVVCIAGDGGFMMTGQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 504 ELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGM-DSFGTEFRfrsaengqlngglvPVDFAAIAAGYGCKTWRVTTLDE 582
Cdd:cd00568 82 ELATAVRYGLPVIVVVFNNGGYGTIRMHQEAFYGgRVSGTDLS--------------NPDFAALAEAYGAKGVRVEDPED 147
|
170 180
....*....|....*....|.
gi 655997487 583 LKIALEAAQRETVSTLIDIKV 603
Cdd:cd00568 148 LEAALAEALAAGGPALIEVKT 168
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
63-594 |
3.26e-35 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 140.33 E-value: 3.26e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 63 RNEQGMAHAATGFARQSLRRQILACTSSVGPGAANMITAAATATANRIPLLLLPGDVfatrqPDPvLQQIEQSYdlsiST 142
Cdd:PRK06154 61 RTERVAVHMADGYARATSGERVGVFAVQYGPGAENAFGGVAQAYGDSVPVLFLPTGY-----PRG-STDVAPNF----ES 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 143 NDAFRAVSKYWDRITRPEQLMsaciNAMRVLTDPAETGA---VTLALPQDVQGEawDYPQSFFARRVHRLDRRPASQAQL 219
Cdd:PRK06154 131 LRNYRHITKWCEQVTLPDEVP----ELMRRAFTRLRNGRpgpVVLELPVDVLAE--ELDELPLDHRPSRRSRPGADPVEV 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 220 NDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVG--GVGETGCLAANLlaKEAD 297
Cdd:PRK06154 205 VEAAALLLAAERPVIYAGQGVLYAQATPELKELAELLEIPVMTTLNGKSAFPEDHPLALGsgGRARPATVAHFL--READ 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 298 LVIGVGTRFTDfttsSKWIFQHP-DVRFLNINVSNFDAWK---LDgIPLLADAREALTALDGAL-GDTAWQAGWGEQIAA 372
Cdd:PRK06154 283 VLFGIGCSLTR----SYYGLPMPeGKTIIHSTLDDADLNKdypID-HGLVGDAALVLKQMIEELrRRVGPDRGRAQQVAA 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 373 vqsrQMKETHRVYQASFQEKgfipeiddhldresvyrefraLT--DSTLTQSNVLGILNETL-PQEAVIVAAAGSLPGDL 449
Cdd:PRK06154 358 ----EIEAVRAAWLAKWMPK---------------------LTsdSTPINPYRVVWELQHAVdIKTVIITHDAGSPRDQL 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 450 QRVWRTRAPNAYhVEYGYSC-MGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGcI 528
Cdd:PRK06154 413 SPFYVASRPGSY-LGWGKTTqLGYGLGLAMGAKLARPDALVINLWGDAAFGMTGMDFETAVRERIPILTILLNNFSMG-G 490
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655997487 529 NNLQMEHGMDSFGTEFrfrsaengqLNGglvpvDFAAIAAGYGCKTWRVTTLDELKIALEAAQRET 594
Cdd:PRK06154 491 YDKVMPVSTTKYRATD---------ISG-----DYAAIARALGGYGERVEDPEMLVPALLRALRKV 542
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
182-606 |
1.43e-33 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 135.29 E-value: 1.43e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 182 VTLALPQDVqgeaWDYPQSffaRRVHRLDRRPA--SQAQLNDAVAAIRA----SRKPLIICGGGVKYSGAGEALAHFAER 255
Cdd:COG3961 163 VYIELPRDV----ADAPIE---PPEAPLPLPPPasDPAALAAAVAAAAErlakAKRPVILAGVEVHRFGLQEELLALAEK 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 256 YRIPFAETQAGKGTLISSHPYNVGG-VGETGCLAANLLAKEADLVIGVGTRFTDFTTsskWIF-QHPDV-RFLNIN---V 329
Cdd:COG3961 236 TGIPVATTLLGKSVLDESHPQFIGTyAGAASSPEVREYVENADCVLCLGVVFTDTNT---GGFtAQLDPeRTIDIQpdsV 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 330 SNFDAWkLDGIPLlADAREALTALDgalgdtawqagwgeqiaavqsrqmkethrvyqasfQEKGFIPEIddhldRESVYR 409
Cdd:COG3961 313 RVGGHI-YPGVSL-ADFLEALAELL-----------------------------------KKRSAPLPA-----PAPPPP 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 410 EFRALTDSTLTQSNVLGILNETLPQEAVIVAAAGS---------LPGDlqrvwrtrapNAYHVEYGYSCMGYEVSAALGV 480
Cdd:COG3961 351 PPPAAPDAPLTQDRLWQRLQAFLDPGDIVVADTGTslfgaadlrLPEG----------ATFIAQPLWGSIGYTLPAALGA 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 481 KLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLfdnmangcINNlqmehgmDSFGTEfRFRSAENGQLNgGLVP 560
Cdd:COG3961 421 ALAAPDRRVILLVGDGAFQLTAQELSTMLRYGLKPIIFV--------LNN-------DGYTIE-RAIHGPDGPYN-DIAN 483
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 655997487 561 VDFAAIAAGYGCK---TWRVTTLDELKIALEAAQRETVS-TLIDIkVLPK 606
Cdd:COG3961 484 WDYAKLPEAFGGGnalGFRVTTEGELEEALAAAEANTDRlTLIEV-VLDK 532
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
1-593 |
9.93e-33 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 133.57 E-value: 9.93e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 1 MGKLRLTMAQALVkfldnqyLEVDGETVKF-VKGIfAIfghgnvLGLGQALEQdSGELRLYQGRNEQGMAHAATGFARQS 79
Cdd:PRK11269 1 MAKMRAVDAAVLV-------LEKEGVTTAFgVPGA-AI------NPFYSAMRK-HGGIRHILARHVEGASHMAEGYTRAT 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 80 LRRqILACTSSVGPGAANMITAAATATANRIPLLLLPGdvfatRQPDPVLQQIE-QSYDL-SIStndafRAVSKYWDRIT 157
Cdd:PRK11269 66 AGN-IGVCIGTSGPAGTDMITGLYSASADSIPILCITG-----QAPRARLHKEDfQAVDIeSIA-----KPVTKWAVTVR 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 158 RPEQLMSACINAMRVLTDpAETGAVTLALPQDVQGEAWDY-PQSFFARRVHRldrrP-ASQAQLNDAVAAIRASRKPLII 235
Cdd:PRK11269 135 EPALVPRVFQQAFHLMRS-GRPGPVLIDLPFDVQVAEIEFdPDTYEPLPVYK----PaATRAQIEKALEMLNAAERPLIV 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 236 CGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVG-ETGCLAANLLAKEADLVIGVGTRFTDFTTSSK 314
Cdd:PRK11269 210 AGGGVINADASDLLVEFAELTGVPVIPTLMGWGAIPDDHPLMAGMVGlQTSHRYGNATLLASDFVLGIGNRWANRHTGSV 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 315 WI------FQHPDVRFLNI-NVSNFDAwkldGIplLADAREALTALDGALgdTAWQAG-----WGEQIAAVQSRqmketh 382
Cdd:PRK11269 290 EVytkgrkFVHVDIEPTQIgRVFGPDL----GI--VSDAKAALELLVEVA--REWKAAgrlpdRSAWVADCQER------ 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 383 rvyQASFQEKgfipeidDHLDR-----ESVYREfraltdstltqsnvlgiLNETLPQEAVIVAAAGslpgdLQRVWRTRA 457
Cdd:PRK11269 356 ---KRTLLRK-------THFDNvpikpQRVYEE-----------------MNKAFGRDTCYVSTIG-----LSQIAAAQF 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 458 PNAYHVEYGYSC-----MGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTsiqeGAKVNV----LLFDNMANGCI 528
Cdd:PRK11269 404 LHVYKPRHWINCgqagpLGWTIPAALGVRAADPDRNVVALSGDYDFQFLIEELAV----GAQFNLpyihVLVNNAYLGLI 479
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 655997487 529 NNLQMEHGMDsFGTEFRFRSAENGQLNG-GlvpVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRE 593
Cdd:PRK11269 480 RQAQRAFDMD-YCVQLAFENINSPELNGyG---VDHVKVAEGLGCKAIRVFKPEDIAPALEQAKAL 541
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
63-605 |
4.73e-31 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 128.28 E-value: 4.73e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 63 RNEQGMAHAATGFARQSlrRQILACTSSVGPGAANMITAAATATANRIPLLLLPGdvfatrqpdpvlqQIEQSYdlsIST 142
Cdd:CHL00099 58 RHEQGAAHAADGYARST--GKVGVCFATSGPGATNLVTGIATAQMDSVPLLVITG-------------QVGRAF---IGT 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 143 nDAFRAVSKYwdRITRP----------EQLMSACINAMRVLTDPAETGAVTLALPQDVQGEAWDYPQSFFARRVHRL-DR 211
Cdd:CHL00099 120 -DAFQEVDIF--GITLPivkhsyvvrdARDISRIVAEAFYIAKHGRPGPVLIDIPKDVGLEKFDYYPPEPGNTIIKIlGC 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 212 RPA---SQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLA 288
Cdd:CHL00099 197 RPIykpTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAELYKIPVTTTLMGKGIFDEDHPLCLGMLGMHGTAY 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 289 ANLLAKEADLVIGVGTRFTDFTTSSKWIFQ-HPDVRFLNINVSNFDAWKLDGIPLLADAREALTAL-------DGALGDT 360
Cdd:CHL00099 277 ANFAVSECDLLIALGARFDDRVTGKLDEFAcNAQVIHIDIDPAEIGKNRIPQVAIVGDVKKVLQELlellknsPNLLESE 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 361 AWQAgWGEQIAAVQsrqmkethRVYQASfqekgfIPEIDDHLDRESVyrefraltdstltqsnvlgiLNET--LPQEAVI 438
Cdd:CHL00099 357 QTQA-WRERINRWR--------KEYPLL------IPKPSTSLSPQEV--------------------INEIsqLAPDAYF 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 439 VAAAG-------SLPGDLQRVWRTRApnayhveyGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQE 511
Cdd:CHL00099 402 TTDVGqhqmwaaQFLKCKPRKWLSSA--------GLGTMGYGLPAAIGAQIAHPNELVICISGDASFQMNLQELGTIAQY 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 512 GAKVNVLLFDNMANGCINNLQmehgmDSF-GTEFRFRSAENGQlngglvPvDFAAIAAGYGCKTWRVTTLDELKIALEAA 590
Cdd:CHL00099 474 NLPIKIIIINNKWQGMVRQWQ-----QAFyGERYSHSNMEEGA------P-DFVKLAEAYGIKGLRIKSRKDLKSSLKEA 541
|
570
....*....|....*
gi 655997487 591 QRETVSTLIDIKVLP 605
Cdd:CHL00099 542 LDYDGPVLIDCQVIE 556
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
32-590 |
6.75e-31 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 127.72 E-value: 6.75e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 32 KGIFAIFGH--GNVLGLGQALEQDSGeLRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANR 109
Cdd:PRK06882 17 EGVEYVFGYpgGSVLDIYDAIHTLGG-IEHVLVRHEQAAVHMADGYARSTGKVGCVLVTS--GPGATNAITGIATAYTDS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 110 IPLLLLPGDVFATRQPDPVLQQIEQsydLSIStndafRAVSKYWDRITRPEQLMSACINAMRVLTDpAETGAVTLALPQD 189
Cdd:PRK06882 94 VPLVILSGQVPSNLIGTDAFQECDM---LGIS-----RPVVKHSFIVKNAEDIPSTIKKAFYIAST-GRPGPVVIDIPKD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 190 VQGEAWDYPQSFfARRVHRLDRRPASQA---QLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAG 266
Cdd:PRK06882 165 MVNPANKFTYEY-PEEVSLRSYNPTVQGhkgQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQKLNLPVTSSLMG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 267 KGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIF-QHPDVRFLNINVSNFDAWKLDGIPLLAD 345
Cdd:PRK06882 244 LGAYPSTDKQFLGMLGMHGTYEANNAMHESDLILGIGVRFDDRTTNNLAKYcPNAKVIHIDIDPTSISKNVPAYIPIVGS 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 346 AREALTALDGALGDTAWQAG------WGEQIAAVQSRQMKETHRVYQAsfqekgfipeIDDHLDRESVYR--EFRALTDS 417
Cdd:PRK06882 324 AKNVLEEFLSLLEEENLAKSqtdltaWWQQINEWKAKKCLEFDRTSDV----------IKPQQVVEAIYRltNGDAYVAS 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 418 TLTQSNVLgilnetlpqeavivaAAGSLPGDLQRVWRTRApnayhveyGYSCMGYEVSAALGVKLAEPQREVYAMVGDGA 497
Cdd:PRK06882 394 DVGQHQMF---------------AALHYPFDKPRRWINSG--------GAGTMGFGLPAAIGVKFAHPEATVVCVTGDGS 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 498 FMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMehgmdsfgtefRFRSAENGQLNGGLVPvDFAAIAAGYGCKTWRV 577
Cdd:PRK06882 451 IQMNIQELSTAKQYDIPVVIVSLNNRFLGMVKQWQD-----------LIYSGRHSQVYMNSLP-DFAKLAEAYGHVGIQI 518
|
570
....*....|...
gi 655997487 578 TTLDELKIALEAA 590
Cdd:PRK06882 519 DTPDELEEKLTQA 531
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
55-604 |
6.19e-30 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 124.33 E-value: 6.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 55 GELRLYQGRNEQGMAHAATGFARQSlrRQILACTSSVGPGAANMITAAATATANRIPLLLLPGDVfATRQPDPVLQQIEQ 134
Cdd:PRK07064 40 GKIRFVPARGEAGAVNMADAHARVS--GGLGVALTSTGTGAGNAAGALVEALTAGTPLLHITGQI-ETPYLDQDLGYIHE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 135 SYD-LSIstndaFRAVSKYWDRITRPEQLMSACINAMRV-LTDPaeTGAVTLALPQDVQGEAWDYPQSFFARRVhrlDRR 212
Cdd:PRK07064 117 APDqLTM-----LRAVSKAAFRVRSAETALATIREAVRVaLTAP--TGPVSVEIPIDIQAAEIELPDDLAPVHV---AVP 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 213 PASQAQLNDAVAAIRASRKPLIICGGGVKysGAGEALAHFAERyRIPFAETQAGKGTLISSHPYNVGGVGETGclAANLL 292
Cdd:PRK07064 187 EPDAAAVAELAERLAAARRPLLWLGGGAR--HAGAEVKRLVDL-GFGVVTSTQGRGVVPEDHPASLGAFNNSA--AVEAL 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 293 AKEADLVIGVGTRFTDFTTsSKWIFQHPDVRF-LNINVSNFDAWKLDGIPLLADAREALTALDGALGDTAW-QAGWGEQI 370
Cdd:PRK07064 262 YKTCDLLLVVGSRLRGNET-LKYSLALPRPLIrVDADAAADGRGYPNDLFVHGDAARVLARLADRLEGRLSvDPAFAADL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 371 AAVqsRQMKETHrvyqasfQEKGFIPeiddhldresvyreFRALTDStltqsnvlgiLNETLPQEAVIV---AAAGSLPG 447
Cdd:PRK07064 341 RAA--REAAVAD-------LRKGLGP--------------YAKLVDA----------LRAALPRDGNWVrdvTISNSTWG 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 448 DlqRVWRTRAPNA-YHVEYGYSCMGyeVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANG 526
Cdd:PRK07064 388 N--RLLPIFEPRAnVHALGGGIGQG--LAMAIGAALAGPGRKTVGLVGDGGLMLNLGELATAVQENANMVIVLMNDGGYG 463
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 655997487 527 CINNLQMEHgmdsfgteFRFRSAENgqlngGLVPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVL 604
Cdd:PRK07064 464 VIRNIQDAQ--------YGGRRYYV-----ELHTPDFALLAASLGLPHWRVTSADDFEAVLREALAKEGPVLVEVDML 528
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
32-590 |
6.47e-29 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 121.88 E-value: 6.47e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 32 KGIFAIFGH--GNVLGLGQALEQDSGeLRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANR 109
Cdd:PRK07979 17 QGVKQVFGYpgGAVLDIYDALHTVGG-IDHVLVRHEQAAVHMADGLARATGEVGVVLVTS--GPGATNAITGIATAYMDS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 110 IPLLLLPGDVfATrqpdpvlqqieqsydlSISTNDAF---------RAVSKYWDRITRPEQLMSACINAMrVLTDPAETG 180
Cdd:PRK07979 94 IPLVVLSGQV-AT----------------SLIGYDAFqecdmvgisRPVVKHSFLVKQTEDIPQVLKKAF-WLAASGRPG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 181 AVTLALPQDVQGEA----WDYPQSFFARRVHrldrrPASQ---AQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFA 253
Cdd:PRK07979 156 PVVVDLPKDILNPAnklpYVWPESVSMRSYN-----PTTQghkGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 254 ERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTS--SKWIfqhPDVRFLNINVSN 331
Cdd:PRK07979 231 EKLNLPVVSSLMGLGAFPATHRQSLGMLGMHGTYEANMTMHNADVIFAVGVRFDDRTTNnlAKYC---PNATVLHIDIDP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 332 FDAWKL--DGIPLLADAREALTALDGALGDTAWQA------GWGEQIAAVQSRQMKETHRVyQASFQEKGFIpeiddhld 403
Cdd:PRK07979 308 TSISKTvtADIPIVGDARQVLEQMLELLSQESAHQpldeirDWWQQIEQWRARQCLKYDTH-SEKIKPQAVI-------- 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 404 rESVYR--EFRALTDSTLTQSNVLgilnetlpqeavivaAAGSLPGDLQRVWRTRApnayhveyGYSCMGYEVSAALGVK 481
Cdd:PRK07979 379 -ETLWRltKGDAYVTSDVGQHQMF---------------AALYYPFDKPRRWINSG--------GLGTMGFGLPAALGVK 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 482 LAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ-MEHgmdsfgtefrfrSAENGQLNGGLVP 560
Cdd:PRK07979 435 MALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVLNLNNRYLGMVKQWQdMIY------------SGRHSQSYMQSLP 502
|
570 580 590
....*....|....*....|....*....|
gi 655997487 561 vDFAAIAAGYGCKTWRVTTLDELKIALEAA 590
Cdd:PRK07979 503 -DFVRLAEAYGHVGIQISHPDELESKLSEA 531
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
57-601 |
9.56e-29 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 121.26 E-value: 9.56e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 57 LRLYQGRNEQGMAHAATGFARQSLRRQilACTSSVGPGAANMITAAATATANRIPLLLLpgdvfaTRQPDPV------LQ 130
Cdd:PRK07525 44 IRFIDVAHEQNAGHMADGYTRVTGRMG--MVIGQNGPGITNFVTAVATAYWAHTPVVLV------TPQAGTKtigqggFQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 131 QIEQSydlsistnDAFRAVSKYWDRITRPEQlMSACINamRVLTDP-AETGAVTLALPQDVqgeaW------DYPQsffa 203
Cdd:PRK07525 116 EAEQM--------PMFEDMTKYQEEVRDPSR-MAEVLN--RVFDKAkRESGPAQINIPRDY----FygvidvEIPQ---- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 204 rrVHRLDRRPASQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGE 283
Cdd:PRK07525 177 --PVRLERGAGGEQSLAEAAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACGYLHNDAFPGSHPLWVGPLGY 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 284 TGCLAANLLAKEADLVIGVGTRFTDFTTSSK-----W-----IFQhpdvrfLNINVSNFDAWKLDGIPLLADAREA---- 349
Cdd:PRK07525 255 NGSKAAMELIAKADVVLALGTRLNPFGTLPQygidyWpkdakIIQ------VDINPDRIGLTKKVSVGICGDAKAVarel 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 350 LTALDGALGDTAWQAGWGEQIAAVQSRQMKEthrvyqasfqekgfIPEIDDHLDRESVYREFRALTDST--LTQSNVLGI 427
Cdd:PRK07525 329 LARLAERLAGDAGREERKALIAAEKSAWEQE--------------LSSWDHEDDDPGTDWNEEARARKPdyMHPRQALRE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 428 LNETLPQEAVIV-------AAAGSLPgdlqrvwRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMM 500
Cdd:PRK07525 395 IQKALPEDAIVStdignncSIANSYL-------RFEKGRKYLAPGSFGNCGYAFPAIIGAKIACPDRPVVGFAGDGAWGI 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 501 LHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSF-GTEFRfrsaengqlngglVPVDFAAIAAGYGCKTWRVTT 579
Cdd:PRK07525 468 SMNEVMTAVRHNWPVTAVVFRNYQWGAEKKNQVDFYNNRFvGTELD-------------NNVSYAGIAEAMGAEGVVVDT 534
|
570 580
....*....|....*....|....*
gi 655997487 580 LDELKIALEAA---QRETVSTLIDI 601
Cdd:PRK07525 535 QEELGPALKRAidaQNEGKTTVIEI 559
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
6-590 |
9.83e-27 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 114.84 E-value: 9.83e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 6 LTMAQALVKFLDNQylevdgetvkfvkGIFAIFGH--GNVLGLGQAL-EQDsgELRLYQGRNEQGMAHAATGFARQSLRR 82
Cdd:PRK06466 4 LSGAEMLVRALRDE-------------GVEYIYGYpgGAVLHIYDALfKQD--KVEHILVRHEQAATHMADGYARATGKT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 83 QILACTSsvGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIEQsydLSIStndafRAVSKYWDRITRPEQL 162
Cdd:PRK06466 69 GVVLVTS--GPGATNAITGIATAYMDSIPMVVLSGQVPSTLIGEDAFQETDM---VGIS-----RPIVKHSFMVKHASEI 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 163 mSACINAMRVLTDPAETGAVTLALPQDV----QGEAWDYPQSFFARrvhrlDRRPASQ---AQLNDAVAAIRASRKPLII 235
Cdd:PRK06466 139 -PEIIKKAFYIAQSGRPGPVVVDIPKDMtnpaEKFEYEYPKKVKLR-----SYSPAVRghsGQIRKAVEMLLAAKRPVIY 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 236 CGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKW 315
Cdd:PRK06466 213 SGGGVVLGNASALLTELAHLLNLPVTNTLMGLGGFPGTDRQFLGMLGMHGTYEANMAMHHADVILAVGARFDDRVTNGPA 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 316 IFQhPDVRFLNINVSNFDAWK--LDGIPLLADAREALTAL------DGALGDTAWQAGWGEQIaavqsRQMKETHRVYQa 387
Cdd:PRK06466 293 KFC-PNAKIIHIDIDPASISKtiKADIPIVGPVESVLTEMlailkeIGEKPDKEALAAWWKQI-----DEWRGRHGLFP- 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 388 sfqekgfipeiddhldresvyreFRALTDSTLTQSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGY 467
Cdd:PRK06466 366 -----------------------YDKGDGGIIKPQQVVETLYEVTNGDAYVTSDVGQHQMFAAQYYKFNKPNRWINSGGL 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 468 SCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ-MEHgmdsfgtEFRF 546
Cdd:PRK06466 423 GTMGFGLPAAMGVKLAFPDQDVACVTGEGSIQMNIQELSTCLQYGLPVKIINLNNGALGMVRQWQdMQY-------EGRH 495
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 655997487 547 RSAENGQLngglvPvDFAAIAAGYGCKTWRVTTLDELKIALEAA 590
Cdd:PRK06466 496 SHSYMESL-----P-DFVKLAEAYGHVGIRITDLKDLKPKLEEA 533
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
424-605 |
1.27e-25 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 103.76 E-value: 1.27e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 424 VLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHS 503
Cdd:cd02014 7 VAAELNKRAPDDAIFTIDVGNVTVWAARHLRMNGKQRFILSGLLATMGNGLPGAIAAKLAYPDRQVIALSGDGGFAMLMG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 504 ELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTEfrfrsaengqlnggLVPVDFAAIAAGYGCKTWRVTTLDEL 583
Cdd:cd02014 87 DLITAVKYNLPVIVVVFNNSDLGFIKWEQEVMGQPEFGVD--------------LPNPDFAKIAEAMGIKGIRVEDPDEL 152
|
170 180
....*....|....*....|..
gi 655997487 584 KIALEAAQRETVSTLIDIKVLP 605
Cdd:cd02014 153 EAALDEALAADGPVVIDVVTDP 174
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
61-605 |
8.26e-25 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 108.76 E-value: 8.26e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 61 QGRNEQGMAHAATGFARqsLRRQILACTSSVGPGAANMITAAATATANRIPLLLLPGDVfatrQPDPVLQQIEQSYDLSi 140
Cdd:PRK06457 44 QVRHEEGAALAASVEAK--ITGKPSACMGTSGPGSIHLLNGLYDAKMDHAPVIALTGQV----ESDMIGHDYFQEVNLT- 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 141 stnDAFRAVSKYWDRITRPEQ----LMSACINAMrvltdpAETGAVTLALPQDVQGEAWDYPQSFfarrvHRLDRRPASQ 216
Cdd:PRK06457 117 ---KLFDDVAVFNQILINPENaeyiIRRAIREAI------SKRGVAHINLPVDILRKSSEYKGSK-----NTEVGKVKYS 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 217 AQLNDAVAAIRASRKPLIICGGGVKysGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEA 296
Cdd:PRK06457 183 IDFSRAKELIKESEKPVLLIGGGTR--GLGKEINRFAEKIGAPIIYTLNGKGILPDLDPKVMGGIGLLGTKPSIEAMDKA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 297 DLVIGVGTRFtdftTSSKWIFQHPDVRFLNINVSNFDAWKLDGIPLLADAREALTAldgalgdtawqagwgeqiaavqsr 376
Cdd:PRK06457 261 DLLIMLGTSF----PYVNFLNKSAKVIQVDIDNSNIGKRLDVDLSYPIPVAEFLNI------------------------ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 377 QMKETHRVYQASFQEkgfipEIDDHLDRESvYREFRalTDSTLTQSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTR 456
Cdd:PRK06457 313 DIEEKSDKFYEELKG-----KKEDWLDSIS-KQENS--LDKPMKPQRVAYIVSQKCKKDAVIVTDTGNVTMWTARHFRAS 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 457 APNAYHVEYGYSCMGYEVSAALGVKLA-EPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEH 535
Cdd:PRK06457 385 GEQTFIFSAWLGSMGIGVPGSVGASFAvENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNSKLGMIKFEQEVM 464
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 536 GMDSFGTEfrfrsaengqlnggLVPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVLP 605
Cdd:PRK06457 465 GYPEWGVD--------------LYNPDFTKIAESIGFKGFRLEEPKEAEEIIEEFLNTKGPAVLDAIVDP 520
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
31-588 |
3.50e-24 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 107.13 E-value: 3.50e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 31 VKGIFAIFGhGNVLGLGQALEQdSGELRLYQGRNEQGMAHAATGFARQSLRRQIlaCTSSVGPGAANMITAAATATANRI 110
Cdd:PLN02470 28 VDTVFAYPG-GASMEIHQALTR-SNCIRNVLCRHEQGEVFAAEGYAKASGKVGV--CIATSGPGATNLVTGLADALLDSV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 111 PLLLLPG---------DVFatrQPDP---VLQQIEQSYDLSISTNDAFRAVSK--YWDRITRPeqlmsacinamrvltdp 176
Cdd:PLN02470 104 PLVAITGqvprrmigtDAF---QETPiveVTRSITKHNYLVMDVEDIPRVIREafFLASSGRP----------------- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 177 aetGAVTLALPQDVQGEA----WDYPQSFFARrVHRLDRRPASqAQLNDAVAAIRASRKPLIICGGGVkySGAGEALAHF 252
Cdd:PLN02470 164 ---GPVLVDIPKDIQQQLavpnWNQPMKLPGY-LSRLPKPPEK-SQLEQIVRLISESKRPVVYVGGGC--LNSSEELREF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 253 AERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIF-QHPDVRFLNINVSN 331
Cdd:PLN02470 237 VELTGIPVASTLMGLGAFPASDELSLQMLGMHGTVYANYAVDSADLLLAFGVRFDDRVTGKLEAFaSRASIVHIDIDPAE 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 332 FDAWKLDGIPLLADAREALTALDGAL-GDTAWQAGWGEQIAAVQSRQMKethrvYQASFQEKGfipeiddhldrESVYRE 410
Cdd:PLN02470 317 IGKNKQPHVSVCADVKLALQGLNKLLeERKAKRPDFSAWRAELDEQKEK-----FPLSYPTFG-----------DAIPPQ 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 411 FRALTDSTLTQSNVlgILNETLPQEAviVAAAGSLPGDLQRVWRTRApnayhveyGYSCMGYEVSAALGVKLAEPQREVY 490
Cdd:PLN02470 381 YAIQVLDELTDGNA--IISTGVGQHQ--MWAAQWYKYKEPRRWLTSG--------GLGAMGFGLPAAIGAAAANPDAIVV 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 491 AMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCInnLQMEhgmDSFGTEFRFRSAENGQLNGGLVPVDFAAIAAGY 570
Cdd:PLN02470 449 DIDGDGSFIMNIQELATIHVENLPVKIMVLNNQHLGMV--VQWE---DRFYKANRAHTYLGDPDAEAEIFPDFLKFAEGC 523
|
570
....*....|....*...
gi 655997487 571 GCKTWRVTTLDELKIALE 588
Cdd:PLN02470 524 KIPAARVTRKSDLREAIQ 541
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
26-532 |
1.44e-23 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 105.27 E-value: 1.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 26 ETVKFVKGifaiFGHGNVLGLGQAL-EQDSGELRLYqgRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAAT 104
Cdd:PRK06965 34 EGVEFIWG----YPGGAVLYIYDELyKQDKIQHVLV--RHEQAAVHAADGYARATGKVGVALVTS--GPGVTNAVTGIAT 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 105 ATANRIPLLLLPGDVfatrqPDPVLQQieqsydlsistnDAFRAVSKYwdRITRPEQLMSACINAMRVLTDP-------A 177
Cdd:PRK06965 106 AYMDSIPMVVISGQV-----PTAAIGQ------------DAFQECDTV--GITRPIVKHNFLVKDVRDLAETvkkafyiA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 178 ET---GAVTLALPQDVQGE--AWDYPQSFFARRVHRLdrRPASQAQLNDAVAAIRASRKPLIICGGGVKYSGAGEALAHF 252
Cdd:PRK06965 167 RTgrpGPVVVDIPKDVSKTpcEYEYPKSVEMRSYNPV--TKGHSGQIRKAVSLLLSAKRPYIYTGGGVILANASRELRQL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 253 AERYRIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTDFTTSSKWIFQHPDVRFLNINV--- 329
Cdd:PRK06965 245 ADLLGYPVTNTLMGLGAYPASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRVIGNPAHFASRPRKIIHIDIdps 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 330 SNFDAWKLDgIPLLADAREALTAL------DGALGDTAWQAGWGEQIAAVQSRQ-MKETHRvyqasfqekgfipeiDDHL 402
Cdd:PRK06965 325 SISKRVKVD-IPIVGDVKEVLKELieqlqtAEHGPDADALAQWWKQIEGWRSRDcLKYDRE---------------SEII 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 403 DRESVYREFRALTDStltqsnvlgilnetlpqEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKL 482
Cdd:PRK06965 389 KPQYVVEKLWELTDG-----------------DAFVCSDVGQHQMWAAQFYRFNEPRRWINSGGLGTMGVGLPYAMGIKM 451
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 655997487 483 AEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ 532
Cdd:PRK06965 452 AHPDDDVVCITGEGSIQMCIQELSTCLQYDTPVKIISLNNRYLGMVRQWQ 501
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
33-588 |
1.75e-23 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 105.17 E-value: 1.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 33 GIFAIFGH--GNVLGLGQALEQDSgELRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANRI 110
Cdd:PRK09107 25 GVEHIFGYpgGAVLPIYDEIFQQD-DIQHILVRHEQGAGHAAEGYARSTGKPGVVLVTS--GPGATNAVTPLQDALMDSI 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 111 PLLLLPGDVfatrqPDPVLqqieqsydlsisTNDAFRAVSKYwdRITRP-----------EQLMSACINAMRVLTDpAET 179
Cdd:PRK09107 102 PLVCITGQV-----PTHLI------------GSDAFQECDTV--GITRPctkhnwlvkdvNDLARVIHEAFHVATS-GRP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 180 GAVTLALPQDVQGEAWDY-PQSFFARRVHRLDRRPASQAQLNDAVAAIRASRKPLIICGGGVKYSG--AGEALAHFAERY 256
Cdd:PRK09107 162 GPVVVDIPKDVQFATGTYtPPQKAPVHVSYQPKVKGDAEAITEAVELLANAKRPVIYSGGGVINSGpeASRLLRELVELT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 257 RIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTD--------FTTSSKWIFQHPDVRFLNIN 328
Cdd:PRK09107 242 GFPITSTLMGLGAYPASGKNWLGMLGMHGTYEANMAMHDCDVMLCVGARFDDritgrldaFSPNSKKIHIDIDPSSINKN 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 329 VsnfdawKLDgIPLLADAR---EALTALDGALG---DTAWQAGWGEQIAAVQSRQmkethrvyqaSFqekgfipeiddhl 402
Cdd:PRK09107 322 V------RVD-VPIIGDVGhvlEDMLRLWKARGkkpDKEALADWWGQIARWRARN----------SL------------- 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 403 dresvyrEFRALTDSTLTQSNVLGILNETLPQEAVIVAAAGSlpgdlQRVWRTR-----APNAYHVEYGYSCMGYEVSAA 477
Cdd:PRK09107 372 -------AYTPSDDVIMPQYAIQRLYELTKGRDTYITTEVGQ-----HQMWAAQffgfeEPNRWMTSGGLGTMGYGLPAA 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 478 LGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ-MEHGMdsfgtefRFRSAENGQLng 556
Cdd:PRK09107 440 LGVQIAHPDALVIDIAGDASIQMCIQEMSTAVQYNLPVKIFILNNQYMGMVRQWQqLLHGN-------RLSHSYTEAM-- 510
|
570 580 590
....*....|....*....|....*....|..
gi 655997487 557 glvPvDFAAIAAGYGCKTWRVTTLDELKIALE 588
Cdd:PRK09107 511 ---P-DFVKLAEAYGAVGIRCEKPGDLDDAIQ 538
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
428-603 |
3.18e-23 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 96.90 E-value: 3.18e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 428 LNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYhveygYSC----MGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHS 503
Cdd:cd02002 10 LAAALPEDAIIVDEAVTNGLPLRDQLPLTRPGSY-----FTLrgggLGWGLPAAVGAALANPDRKVVAIIGDGSFMYTIQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 504 ELVTSIQEGAKVNVLLFDnmaNGCINNLQMEhgMDSFGTEfrfRSAENGQLNGGLV--PVDFAAIAAGYGCKTWRVTTLD 581
Cdd:cd02002 85 ALWTAARYGLPVTVVILN---NRGYGALRSF--LKRVGPE---GPGENAPDGLDLLdpGIDFAAIAKAFGVEAERVETPE 156
|
170 180
....*....|....*....|..
gi 655997487 582 ELKIALEAAQRETVSTLIDIKV 603
Cdd:cd02002 157 ELDEALREALAEGGPALIEVVV 178
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
63-601 |
4.05e-23 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 103.91 E-value: 4.05e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 63 RNEQGMAHAATgfARQSLRRQILACTSSVGPGAanmitaaatatanripLLLLPGDVFATRQPDPVL--------QQIEQ 134
Cdd:PRK06546 48 RHEEAAAFAAA--AEAQLTGKLAVCAGSCGPGN----------------LHLINGLYDAHRSGAPVLaiashipsAQIGS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 135 SYDLSISTNDAFRAVSKYWDRITRPEQ----LMSACINAMrvltdpAETGAVTLALPQDVQGEawDYPQSFFARRVhrLD 210
Cdd:PRK06546 110 GFFQETHPDRLFVECSGYCEMVSSAEQaprvLHSAIQHAV------AGGGVSVVTLPGDIADE--PAPEGFAPSVI--SP 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 211 RRPA---SQAQLNDAVAAIRASRKPLIICGGGVKysGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETGCL 287
Cdd:PRK06546 180 RRPTvvpDPAEVRALADAINEAKKVTLFAGAGVR--GAHAEVLALAEKIKAPVGHSLRGKEWIQYDNPFDVGMSGLLGYG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 288 AANLLAKEADLVIGVGTRF--TDFTtsskwifqhPDVRFLNINVsnfDAWKLD-----GIPLLADAREALTAL------- 353
Cdd:PRK06546 258 AAHEAMHEADLLILLGTDFpyDQFL---------PDVRTAQVDI---DPEHLGrrtrvDLAVHGDVAETIRALlplvkek 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 354 -DGALGDtawqagwgeQIAAVQSRQMKE-----THRVyqasfqEKgfipeiddhldRESVYREFRAltdstltqsnvlGI 427
Cdd:PRK06546 326 tDRRFLD---------RMLKKHARKLEKvvgayTRKV------EK-----------HTPIHPEYVA------------SI 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 428 LNETLPQEAVIVAAAGslpgdLQRVWRTR--APNAYHVEYG---YSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLH 502
Cdd:PRK06546 368 LDELAADDAVFTVDTG-----MCNVWAARyiTPNGRRRVIGsfrHGSMANALPHAIGAQLADPGRQVISMSGDGGLSMLL 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 503 SELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTEFRfrsaengqlngglvPVDFAAIAAGYGCKTWRVTTLDE 582
Cdd:PRK06546 443 GELLTVKLYDLPVKVVVFNNSTLGMVKLEMLVDGLPDFGTDHP--------------PVDYAAIAAALGIHAVRVEDPKD 508
|
570
....*....|....*....
gi 655997487 583 LKIALEAAQRETVSTLIDI 601
Cdd:PRK06546 509 VRGALREAFAHPGPALVDV 527
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
428-603 |
5.91e-22 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 93.51 E-value: 5.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 428 LNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVT 507
Cdd:cd02010 8 LRAVMGDDDIVLLDVGAHKIWMARYYRTYAPNTCLISNGLATMGVALPGAIGAKLVYPDRKVVAVSGDGGFMMNSQELET 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 508 SIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTEFRfrsaengqlngglvPVDFAAIAAGYGCKTWRVTTLDELKIAL 587
Cdd:cd02010 88 AVRLKIPLVVLIWNDNGYGLIKWKQEKEYGRDSGVDFG--------------NPDFVKYAESFGAKGYRIESADDLLPVL 153
|
170
....*....|....*.
gi 655997487 588 EAAQRETVSTLIDIKV 603
Cdd:cd02010 154 ERALAADGVHVIDCPV 169
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
153-590 |
9.91e-22 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 99.30 E-value: 9.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 153 WD-RITRPEQLMSACINAMRVL-TDPAetGAVTLALPQDVQGEAWDYPQSFFARRVHRldRRPASQAQ-LNDAVAAIRAS 229
Cdd:PRK08327 145 WDyEIRRGDQIGEVVARAIQIAmSEPK--GPVYLTLPREVLAEEVPEVKADAGRQMAP--APPAPDPEdIARAAEMLAAA 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 230 RKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGVGETgclaanLLAkEADLVIGVGT----- 304
Cdd:PRK08327 221 ERPVIITWRAGRTAEGFASLRRLAEELAIPVVEYAGEVVNYPSDHPLHLGPDPRA------DLA-EADLVLVVDSdvpwi 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 305 -RFTDFTTSSKWIFQHPDVRFLNINVSNFDAwkldGIPLLADAREALTALDGALGDTawqagWGEQIAAVQSRQMKETHR 383
Cdd:PRK08327 294 pKKIRPDADARVIQIDVDPLKSRIPLWGFPC----DLCIQADTSTALDQLEERLKSL-----ASAERRRARRRRAAVREL 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 384 VYQasfQEKGFIPEIDDHLDRESVYREFraltdstltqsnVLGILNETLPQEAVIVAAAGSLPGDLqrvwRTRAPNAYHV 463
Cdd:PRK08327 365 RIR---QEAAKRAEIERLKDRGPITPAY------------LSYCLGEVADEYDAIVTEYPFVPRQA----RLNKPGSYFG 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 464 EYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLL--FDNMANGCINNLQMEhgMDSFG 541
Cdd:PRK08327 426 DGSAGGLGWALGAALGAKLATPDRLVIATVGDGSFIFGVPEAAHWVAERYGLPVLVvvFNNGGWLAVKEAVLE--VYPEG 503
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 655997487 542 TefrfrSAENGQLNGGLV--PVDFAAIAAGYGCKTWRVTTLDELKIALEAA 590
Cdd:PRK08327 504 Y-----AARKGTFPGTDFdpRPDFAKIAEAFGGYGERVEDPEELKGALRRA 549
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
424-609 |
1.28e-21 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 92.56 E-value: 1.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 424 VLGILNETLPQEAVIVA--------AAgslpgdlqRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGD 495
Cdd:cd02015 6 VIKELSELTPGDAIVTTdvgqhqmwAA--------QYYRFKKPRSWLTSGGLGTMGFGLPAAIGAKVARPDKTVICIDGD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 496 GAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQ-MEHGMDSFGTEFRFRsaengqlngglvpVDFAAIAAGYGCKT 574
Cdd:cd02015 78 GSFQMNIQELATAAQYNLPVKIVILNNGSLGMVRQWQeLFYEGRYSHTTLDSN-------------PDFVKLAEAYGIKG 144
|
170 180 190
....*....|....*....|....*....|....*
gi 655997487 575 WRVTTLDELKIALEAAQRETVSTLIDIKVLPKTMV 609
Cdd:cd02015 145 LRVEKPEELEAALKEALASDGPVLLDVLVDPEENV 179
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
10-188 |
2.05e-19 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 85.28 E-value: 2.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 10 QALVKFLDNQYlevdgetvkfVKGIFAIFGHGNvLGLGQALEQDsgELRLYQGRNEQGMAHAATGFARQSLRRQilACTS 89
Cdd:cd07035 1 DALVEALKAEG----------VDHVFGVPGGAI-LPLLDALARS--GIRYILVRHEQGAVGMADGYARATGKPG--VVLV 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 90 SVGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIEQsydlsistNDAFRAVSKYWDRITRPEQLMSACINA 169
Cdd:cd07035 66 TSGPGLTNAVTGLANAYLDSIPLLVITGQRPTAGEGRGAFQEIDQ--------VALFRPITKWAYRVTSPEEIPEALRRA 137
|
170
....*....|....*....
gi 655997487 170 MRVLTDPAeTGAVTLALPQ 188
Cdd:cd07035 138 FRIALSGR-PGPVALDLPK 155
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
158-604 |
3.53e-19 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 91.17 E-value: 3.53e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 158 RPEQLMSACINAMRVLTDPAeTGAVTLALPQDvqgeAWDYP-QSFFARRVHRlDRRPaSQAQLNDAVAAIRASRKPLIIC 236
Cdd:PRK07092 141 RAEDVPAAIARAYHIAMQPP-RGPVFVSIPYD----DWDQPaEPLPARTVSS-AVRP-DPAALARLGDALDAARRPALVV 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 237 GGGVKYSGAGEALAHFAERYRIP-FAETQAGKGTLISSHPyNVGGVGETGCLAANLLAKEADLVIGVGT----------- 304
Cdd:PRK07092 214 GPAVDRAGAWDDAVRLAERHRAPvWVAPMSGRCSFPEDHP-LFAGFLPASREKISALLDGHDLVLVIGApvftyhvegpg 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 305 RFTDFTTSSKWIFQHPDVRflninvsnfdAWKLDGIPLLADAREALTALDGALGDTawqagwgeQIAAVQSRQMKEThrv 384
Cdd:PRK07092 293 PHLPEGAELVQLTDDPGEA----------AWAPMGDAIVGDIRLALRDLLALLPPS--------ARPAPPARPMPPP--- 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 385 yqasfqekgfipeiddhldresvyrefRALTDSTLTQSNVLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYhve 464
Cdd:PRK07092 352 ---------------------------APAPGEPLSVAFVLQTLAALRPADAIVVEEAPSTRPAMQEHLPMRRQGSF--- 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 465 ygYSC----MGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGcinnlqmehGMDSF 540
Cdd:PRK07092 402 --YTMasggLGYGLPAAVGVALAQPGRRVIGLIGDGSAMYSIQALWSAAQLKLPVTFVILNNGRYG---------ALRWF 470
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 655997487 541 GTEFRFRSAENGQLNGglvpVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKVL 604
Cdd:PRK07092 471 APVFGVRDVPGLDLPG----LDFVALARGYGCEAVRVSDAAELADALARALAADGPVLVEVEVA 530
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
424-603 |
8.75e-19 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 84.12 E-value: 8.75e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 424 VLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAF---MM 500
Cdd:cd02004 4 VLHELQEALPDDAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALARPDKRVVLVEGDGAFgfsGM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 501 lhsELVTSIQEGAKVNVLLFDNMANGCINNLQMEhgmdsfgtefrfrsAENGQLNGG--LVPVDFAAIAAGYGCKTWRVT 578
Cdd:cd02004 84 ---ELETAVRYNLPIVVVVGNNGGWYQGLDGQQL--------------SYGLGLPVTtlLPDTRYDLVAEAFGGKGELVT 146
|
170 180
....*....|....*....|....*
gi 655997487 579 TLDELKIALEAAQRETVSTLIDIKV 603
Cdd:cd02004 147 TPEELKPALKRALASGKPALINVII 171
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
45-590 |
3.19e-18 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 88.51 E-value: 3.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 45 GLGQALEQDsGELRLYQGRNEQGMAHAATGFArqSLRRQILACTSSVGPGAanmitaaatatanripLLLLPGDVFATRQ 124
Cdd:PRK09124 31 GLSDSLRRM-GTIEWMHTRHEEVAAFAAGAEA--QLTGELAVCAGSCGPGN----------------LHLINGLFDCHRN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 125 PDPVL--------QQIEQSYDLSISTNDAFRAVSKYWDRITRPEQLMSACINAMRVLTDpaETGAVTLALPQDVQ-GEAW 195
Cdd:PRK09124 92 HVPVLaiaahipsSEIGSGYFQETHPQELFRECSHYCELVSNPEQLPRVLAIAMRKAIL--NRGVAVVVLPGDVAlKPAP 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 196 DYPQSFFARRVHRLdRRPAsQAQLNDAVAAIRASRKPLIICGGGVkySGAGEALAHFAERYRIPFAETQAGKGTLISSHP 275
Cdd:PRK09124 170 ERATPHWYHAPQPV-VTPA-EEELRKLAALLNGSSNITLLCGSGC--AGAHDELVALAETLKAPIVHALRGKEHVEYDNP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 276 YNVGGVGETGCLAANLLAKEADLVIGVGTRF--TDFTTSSKWIFQhpdvrfLNINVSNFDA-WKLDgIPLLADAREALTA 352
Cdd:PRK09124 246 YDVGMTGLIGFSSGYHAMMNCDTLLMLGTDFpyRQFYPTDAKIIQ------IDINPGSLGRrSPVD-LGLVGDVKATLAA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 353 LdgalgdtawqagwgeqiaavQSRQMKETHRvyqasfqekgfipeidDHLDRE-SVYREFRALTDSTLTQSN-------- 423
Cdd:PRK09124 319 L--------------------LPLLEEKTDR----------------KFLDKAlEHYRKARKGLDDLAVPSDggkpihpq 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 424 -VLGILNETLPQEAVIVAAAGSlPgdlqRVWRTRapnaY---------HVEYGYSCMGYEVSAALGVKLAEPQREVYAMV 493
Cdd:PRK09124 363 yLARQISEFAADDAIFTCDVGT-P----TVWAAR----YlkmngkrrlLGSFNHGSMANAMPQALGAQAAHPGRQVVALS 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 494 GDGAFMMLHSELVTSIQEGAKVNVLLFDnmaNGCINNLQMEH---GMDSFGTEfrfrsaengqlnggLVPVDFAAIAAGY 570
Cdd:PRK09124 434 GDGGFSMLMGDFLSLVQLKLPVKIVVFN---NSVLGFVAMEMkagGYLTDGTD--------------LHNPDFAAIAEAC 496
|
570 580
....*....|....*....|
gi 655997487 571 GCKTWRVTTLDELKIALEAA 590
Cdd:PRK09124 497 GITGIRVEKASELDGALQRA 516
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
57-498 |
1.80e-16 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 82.85 E-value: 1.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 57 LRLYQGRNEQGMAHAATGFARQSLRRQILACTSsvGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIEQSy 136
Cdd:PRK05858 43 IRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTA--GPGVTNGMSAMAAAQFNQSPLVVLGGRAPALRWGMGSLQEIDHV- 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 137 dlsistnDAFRAVSKYWDRITRPEQLMSACINAMRVLTDPaETGAVTLALPQDV---QGEAWDYPQSffarrvhrLDRRP 213
Cdd:PRK05858 120 -------PFVAPVTKFAATAQSAENAGRLVDQALQAAVTP-HRGPVFVDFPMDHafsMADDDGRPGA--------LTELP 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 214 ASQAQLNDAVAA----IRASRKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGGvgetgclAA 289
Cdd:PRK05858 184 AGPTPDPDALARaaglLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGRGVVPADHPLAFSR-------AR 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 290 NLLAKEADLVIGVGTRFtDFTTSSKWIFQHPDVrflnINVSNFDAWKLDGIPLLA----DAREALTALDGALGDTAWQAG 365
Cdd:PRK05858 257 GKALGEADVVLVVGVPM-DFRLGFGVFGGTAQL----VHVDDAPPQRAHHRPVAAglygDLSAILSALAGAGGDRTDHQG 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 366 WGEQIAAVQSrqmkethrvyqasfqekgfipeiddhldrESVYREFRALTDST--LTQSNVLGILNETLPQEAVIVAAAG 443
Cdd:PRK05858 332 WIEELRTAET-----------------------------AARARDAAELADDRdpIHPMRVYGELAPLLDRDAIVIGDGG 382
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 655997487 444 SLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAF 498
Cdd:PRK05858 383 DFVSYAGRYIDPYRPGCWLDPGPFGCLGTGPGYALAARLARPSRQVVLLQGDGAF 437
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
9-193 |
1.82e-16 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 77.28 E-value: 1.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 9 AQALVKFLDNQYlevdgetvkfVKGIFAIFGhGNVLGLGQALEqDSGELRLYQGRNEQGMAHAATGFARQSLRRQILACT 88
Cdd:pfam02776 2 AEALADVLKALG----------VDTVFGVPG-GHILPLLDALA-KSPGIRYVLTRHEQGAAFAADGYARATGKPGVVLVT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 89 SsvGPGAANMITAAATATANRIPLLLLPGDVFATRQPDPVLQQIeqsydlsISTNDAFRAVSKYWDRITRPEQLMSACIN 168
Cdd:pfam02776 70 S--GPGATNALTGLANAYVDSVPLLVISGQRPRSLVGRGALQQE-------LDQLALFRPVTKWAVRVTSADEIPEVLRR 140
|
170 180
....*....|....*....|....*
gi 655997487 169 AMRVLTDPaETGAVTLALPQDVQGE 193
Cdd:pfam02776 141 AFRAALSG-RPGPVYLEIPLDVLLE 164
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
424-605 |
4.06e-15 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 74.08 E-value: 4.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 424 VLGILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHS 503
Cdd:cd02013 9 VLRELEKAMPEDAIVSTDIGNICSVANSYLRFEKPRSFIAPLSFGNCGYALPAIIGAKAAAPDRPVVAIAGDGAWGMSMM 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 504 ELVTSIQEGAKVNVLLFDNMANGCINNLQmehgmdsfgTEF---RFRSAEngqlnggLVPVDFAAIAAGYGCKTWRVTTL 580
Cdd:cd02013 89 EIMTAVRHKLPVTAVVFRNRQWGAEKKNQ---------VDFynnRFVGTE-------LESESFAKIAEACGAKGITVDKP 152
|
170 180
....*....|....*....|....*...
gi 655997487 581 DELKIALE---AAQRETVSTLIDIKVLP 605
Cdd:cd02013 153 EDVGPALQkaiAMMAEGKTTVIEIVCDQ 180
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
9-603 |
1.44e-14 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 76.82 E-value: 1.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 9 AQALVKFLDNQylevdGetvkfVKGIFAIFGhGNVLGLGQALEQDSGELRLyqGRNEQGMAHAATGFARQSLRRQILACT 88
Cdd:PRK08617 8 ADLVVDSLINQ-----G-----VKYVFGIPG-AKIDRVFDALEDSGPELIV--TRHEQNAAFMAAAIGRLTGKPGVVLVT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 89 SsvGPGAAnmitaaatataNripllLLPGDVFATRQPDPV------------LQQIEQSYDlsisTNDAFRAVSKYWDRI 156
Cdd:PRK08617 75 S--GPGVS-----------N-----LATGLVTATAEGDPVvaiggqvkradrLKRTHQSMD----NVALFRPITKYSAEV 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 157 TRPEQLMSACINAMRVltdpAET---GAVTLALPQDVQGEawdyPQSFFARRVHRLDRR-PASQAQLNDAVAAIRASRKP 232
Cdd:PRK08617 133 QDPDNLSEVLANAFRA----AESgrpGAAFVSLPQDVVDA----PVTSKAIAPLSKPKLgPASPEDINYLAELIKNAKLP 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 233 LIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLisSHPYN---VGGVGetgcLAAN----LLAKEADLVIGVG-- 303
Cdd:PRK08617 205 VLLLGMRASSPEVTAAIRRLLERTNLPVVETFQAAGVI--SRELEdhfFGRVG----LFRNqpgdELLKKADLVITIGyd 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 304 -----TRFtdfttsskWIFqHPDVRFLNINV--SNFDAWKLDGIPLLADAREALTALDGALGDTAWQAGWGEQIAAVqsR 376
Cdd:PRK08617 279 pieyePRN--------WNS-EGDATIIHIDVlpAEIDNYYQPERELIGDIAATLDLLAEKLDGLSLSPQSLEILEEL--R 347
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 377 QMKETHRVYQASFQEKGFIPeiddhLDresVYREFRALT--DSTLTqsnvlgilnetlpqeaVIVaaaGSLPGDLQRVWR 454
Cdd:PRK08617 348 AQLEELAERPARLEEGAVHP-----LR---IIRALQDIVtdDTTVT----------------VDV---GSHYIWMARYFR 400
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 455 TRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAK-VNVLLFDNMANGCINNLQM 533
Cdd:PRK08617 401 SYEPRHLLFSNGMQTLGVALPWAIAAALVRPGKKVVSVSGDGGFLFSAMELETAVRLKLNiVHIIWNDGHYNMVEFQEEM 480
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 534 EHGmDSFGTEFrfrsaenGqlngglvPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK08617 481 KYG-RSSGVDF-------G-------PVDFVKYAESFGAKGLRVTSPDELEPVLREALATDGPVVIDIPV 535
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
418-606 |
1.92e-14 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 71.80 E-value: 1.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 418 TLTQSNVLGILNETLPQEAVIVAAAGS---------LPGDLQrvwrtrapnaYHVEYGYSCMGYEVSAALGVKLAEPQRE 488
Cdd:cd02005 1 PLTQARLWQQVQNFLKPNDILVAETGTswfgaldlkLPKGTR----------FISQPLWGSIGYSVPAALGAALAAPDRR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 489 VYAMVGDGAFMMLHSELVTSIQEGAKVNVLLfdnmangcINNlqmehgmDSFGTEfRFrsaengqLNGG------LVPVD 562
Cdd:cd02005 71 VILLVGDGSFQMTVQELSTMIRYGLNPIIFL--------INN-------DGYTIE-RA-------IHGPeasyndIANWN 127
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 655997487 563 FAAIA----AGYGCKTWRVTTLDELKIALEAAQRET-VSTLIDIkVLPK 606
Cdd:cd02005 128 YTKLPevfgGGGGGLSFRVKTEGELDEALKDALFNRdKLSLIEV-ILPK 175
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
155-605 |
1.19e-13 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 73.87 E-value: 1.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 155 RITRPEQLMSACINAMRVLTDpAETGAVTLALPQDVQGEAWDYPQSffARRVHRL-DRRPA---SQAQLNDAVAAIRASR 230
Cdd:PRK09259 138 RVNRAEDIGIGVARAIRTAVS-GRPGGVYLDLPAKVLAQTMDADEA--LTSLVKVvDPAPAqlpAPEAVDRALDLLKKAK 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 231 KPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVGgvgetgclAANLLA-KEADLVIGVGTRFTdf 309
Cdd:PRK09259 215 RPLIILGKGAAYAQADEQIREFVEKTGIPFLPMSMAKGLLPDTHPQSAA--------AARSLAlANADVVLLVGARLN-- 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 310 ttsskWIFQH-------PDVRF--LNINVSNFDAWKLDGIPLLADAREALTALDGALGDTAWQAG--WGEQIAAVQSRQM 378
Cdd:PRK09259 285 -----WLLSHgkgktwgADKKFiqIDIEPQEIDSNRPIAAPVVGDIGSVMQALLAGLKQNTFKAPaeWLDALAERKEKNA 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 379 KETHRVYQASFQEKGF---IPEIDDhldresVYREFRaltDSTLTQ--SNVL----GILNETLPQEAVIVAAAGSLpgdl 449
Cdd:PRK09259 360 AKMAEKLSTDTQPMNFynaLGAIRD------VLKENP---DIYLVNegANTLdlarNIIDMYKPRHRLDCGTWGVM---- 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 450 qrvwrtrapnayhveyGYScMGYEVSAALgvklaEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNmaNGCIN 529
Cdd:PRK09259 427 ----------------GIG-MGYAIAAAV-----ETGKPVVAIEGDSAFGFSGMEVETICRYNLPVTVVIFNN--GGIYR 482
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 530 nlqmehgmdsfGTEfrfrsaENGQLNGGLVPVDFAA------IAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:PRK09259 483 -----------GDD------VNLSGAGDPSPTVLVHharydkMMEAFGGVGYNVTTPDELRHALTEAIASGKPTLINVVI 545
|
..
gi 655997487 604 LP 605
Cdd:PRK09259 546 DP 547
|
|
| TPP_PpyrDC |
cd03371 |
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of ... |
427-605 |
2.14e-13 |
|
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. These proteins require TPP and divalent metal cation cofactors.
Pssm-ID: 239468 [Multi-domain] Cd Length: 188 Bit Score: 68.88 E-value: 2.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 427 ILNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELV 506
Cdd:cd03371 7 IVLSRAPATAAVVSTTGMTSRELFELRDRPGGGHAQDFLTVGSMGHASQIALGIALARPDRKVVCIDGDGAALMHMGGLA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 507 TSIQEGAKvNV--LLFDnmaNGCinnlqmeHgmDSFGtefrfrsaenGQLNGGlVPVDFAAIAAGYG-CKTWRVTTLDEL 583
Cdd:cd03371 87 TIGGLAPA-NLihIVLN---NGA-------H--DSVG----------GQPTVS-FDVSLPAIAKACGyRAVYEVPSLEEL 142
|
170 180
....*....|....*....|..
gi 655997487 584 KIALEAAQRETVSTLIDIKVLP 605
Cdd:cd03371 143 VAALAKALAADGPAFIEVKVRP 164
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
470-592 |
3.73e-13 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 68.85 E-value: 3.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 470 MGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDsFGTEFRFRSA 549
Cdd:cd02006 59 LGWTVPAALGVAAADPDRQVVALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLGLIRQAQRAFDMD-YQVNLAFENI 137
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 655997487 550 ENGQLNGglVPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQR 592
Cdd:cd02006 138 NSSELGG--YGVDHVKVAEGLGCKAIRVTKPEELAAAFEQAKK 178
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
31-507 |
7.68e-12 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 68.40 E-value: 7.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 31 VKGIFAIFGHGnVLGLGQALEQDSGELRLYQGRNEQGMAHAATGFARQSlrRQILACTSSVGPGAANmitaaatatanri 110
Cdd:PRK08273 18 VRRVFGYPGDG-INGLLGALGRADDKPEFVQARHEEMAAFMAVAHAKFT--GEVGVCLATSGPGAIH------------- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 111 pllLLPGDVFATRQPDPVLQQIEQ--------SYDLSISTNDAFRAV-SKYWDRITRPEQLMSACINAMRVLTdpAETGA 181
Cdd:PRK08273 82 ---LLNGLYDAKLDHVPVVAIVGQqaraalggHYQQEVDLQSLFKDVaGAFVQMVTVPEQLRHLVDRAVRTAL--AERTV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 182 VTLALPQDVQGEAWDYPQSFFARrVHRL--DRRPA---SQAQLNDAVAAIRASRKPLIICGGGVKysGAGEALAHFAERY 256
Cdd:PRK08273 157 TAVILPNDVQELEYEPPPHAHGT-VHSGvgYTRPRvvpYDEDLRRAAEVLNAGRKVAILVGAGAL--GATDEVIAVAERL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 257 RIPFAETQAGKGTLISSHPYNVGGVGETGCLAANLLAKEADLVIGVGTRFTdfttSSKWIFQHPDVRFLNINvsnfdawk 336
Cdd:PRK08273 234 GAGVAKALLGKAALPDDLPWVTGSIGLLGTKPSYELMRECDTLLMVGSSFP----YSEFLPKEGQARGVQID-------- 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 337 LDG----------IPLLADAREALTALDGAL---GDTAWQagwgEQIAavqsRQMKETHRVYQASFQEKGfipeidDHLD 403
Cdd:PRK08273 302 IDGrmlglrypmeVNLVGDAAETLRALLPLLerkKDRSWR----ERIE----KWVARWWETLEARAMVPA------DPVN 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 404 RESVYREfraltdstltqsnvlgiLNETLPQEAVIVAAAGSLPGDLQRVWRTRAPNAYHVEYGYSCMGYEVSAALGVKLA 483
Cdd:PRK08273 368 PQRVFWE-----------------LSPRLPDNAILTADSGSCANWYARDLRMRRGMMASLSGTLATMGPAVPYAIAAKFA 430
|
490 500
....*....|....*....|....*
gi 655997487 484 EPQREVYAMVGDGAFMMLH-SELVT 507
Cdd:PRK08273 431 HPDRPVIALVGDGAMQMNGmAELIT 455
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
183-600 |
1.63e-10 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 63.71 E-value: 1.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 183 TLALPQDVqgeAWDyPQSFFARRVHRLDRRPASQAQLNDAVAAIRASRKPLIICGGGVkYSGAGEALAHfaeryRI---- 258
Cdd:PRK07586 155 TLILPADV---AWS-EGGPPAPPPPAPAPAAVDPAAVEAAAAALRSGEPTVLLLGGRA-LRERGLAAAA-----RIaaat 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 259 ---PFAET-----QAGKGTL-ISSHPYnvggVGEtgcLAANLLAkEADLVIGVGTRftdfttSSKWIFQHPDVRflninv 329
Cdd:PRK07586 225 garLLAETfparmERGAGRPaVERLPY----FAE---QALAQLA-GVRHLVLVGAK------APVAFFAYPGKP------ 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 330 snfDAWKLDGIPLLA------DAREALTALDGALGdtawqAGWGEQIAAVQSRQMKETHRvyqasfqekgfipeiddhld 403
Cdd:PRK07586 285 ---SRLVPEGCEVHTlagpgeDAAAALEALADALG-----AKPAAPPLAAPARPPLPTGA-------------------- 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 404 resvyrefraltdstLTQSNVLGILNETLPQEAVIV------------AAAGSLPGDlqrvWRTRAPNAyhveygyscMG 471
Cdd:PRK07586 337 ---------------LTPEAIAQVIAALLPENAIVVdesitsgrgffpATAGAAPHD----WLTLTGGA---------IG 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 472 YEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVNVLLFdnmANGCINNLQMEhgMDSFGTEFRFRSAeN 551
Cdd:PRK07586 389 QGLPLATGAAVACPDRKVLALQGDGSAMYTIQALWTQARENLDVTTVIF---ANRAYAILRGE--LARVGAGNPGPRA-L 462
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 655997487 552 GQLNGGLVPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLID 600
Cdd:PRK07586 463 DMLDLDDPDLDWVALAEGMGVPARRVTTAEEFADALAAALAEPGPHLIE 511
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
31-191 |
3.00e-08 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 53.32 E-value: 3.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 31 VKGIFAIFGHGNvLGLGQALeQDSGELRLYQGRNEQGMAHAATGFARqsLRRQILACTSSVGPGAANMITAAATATANRI 110
Cdd:cd07039 15 VKRVYGIPGDSI-NGLMDAL-RREGKIEFIQVRHEEAAAFAASAEAK--LTGKLGVCLGSSGPGAIHLLNGLYDAKRDRA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 111 PLLLLPGDVfatrqpdpVLQQIEQSYDLSISTNDAFRAVSKYWDRITRPEQLMSACINAMRvlTDPAETGAVTLALPQDV 190
Cdd:cd07039 91 PVLAIAGQV--------PTDELGTDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRAIR--TAIAKRGVAVLILPGDV 160
|
.
gi 655997487 191 Q 191
Cdd:cd07039 161 Q 161
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
214-611 |
5.12e-08 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 55.86 E-value: 5.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 214 ASQAQLNDAVaairasrKPLIICGGGVKYSGAGEALAHFAERYRIPFAETQAGKGTLISSHPYNVG---GVGETGCLAAn 290
Cdd:PLN02573 216 AAAEFLNKAV-------KPVLVGGPKLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHHPHFIGtywGAVSTPFCAE- 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 291 lLAKEADLVIGVGTRFTDFTT--------SSKWIFQHPDvrflNINVSNFDAWkldGIPLLADAREALtaldgalgdtaw 362
Cdd:PLN02573 288 -IVESADAYLFAGPIFNDYSSvgyslllkKEKAIIVQPD----RVTIGNGPAF---GCVLMKDFLEAL------------ 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 363 qagwgeqiaAVQSRQMKETHRVYQASFQEKGFIPEIDDHldresvyrefRALTDSTLTQsNVLGILNetlPQEAVIVAAA 442
Cdd:PLN02573 348 ---------AKRVKKNTTAYENYKRIFVPEGEPLKSEPG----------EPLRVNVLFK-HIQKMLS---GDTAVIAETG 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 443 GSlpgdlqrvW----RTRAPN--AYHVEYGYSCMGYEVSAALGVKLAEPQREVYAMVGDGAFMMLHSELVTSIQEGAKVN 516
Cdd:PLN02573 405 DS--------WfncqKLKLPEgcGYEFQMQYGSIGWSVGATLGYAQAAPDKRVIACIGDGSFQVTAQDVSTMIRCGQKSI 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 517 VLLfdnmangcINNlqmehGMDSFGTEFrfrsaENGQLN-------GGLVpvdfAAIAAGYG-CKTWRVTTLDELKIALE 588
Cdd:PLN02573 477 IFL--------INN-----GGYTIEVEI-----HDGPYNviknwnyTGLV----DAIHNGEGkCWTAKVRTEEELIEAIA 534
|
410 420
....*....|....*....|...
gi 655997487 589 AAQRETVSTLIDIKVlpktMVHK 611
Cdd:PLN02573 535 TATGEKKDCLCFIEV----IVHK 553
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
469-599 |
1.89e-07 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 51.51 E-value: 1.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 469 CMGYEVSAALGVKLAEPQREVYAMVGDGAFmmLHS---ELVTSIQEGAKVNVLLFDNMANGcinnlqMEHGMDSFGTEFR 545
Cdd:cd02008 52 CMGASIGVAIGMAKASEDKKVVAVIGDSTF--FHSgilGLINAVYNKANITVVILDNRTTA------MTGGQPHPGTGKT 123
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 655997487 546 FRSAENgqlngglvPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRET----VSTLI 599
Cdd:cd02008 124 LTEPTT--------VIDIEALVRAIGVKRVVVVDPYDLKAIREELKEALavpgVSVII 173
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
474-603 |
3.66e-07 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 50.67 E-value: 3.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 474 VSAALGVKLAEPQReVYAMVGDGAFmmLH---SELVTSiQEGAKVNVLLFDNmaNGcinnlqmehgmdsfGTEFRF---- 546
Cdd:cd02009 57 LSTALGIALATDKP-TVLLTGDLSF--LHdlnGLLLGK-QEPLNLTIVVINN--NG--------------GGIFSLlpqa 116
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 655997487 547 -RSAENGQLNGGLVPVDFAAIAAGYGCKTWRVTTLDELKIALEAAQRETVSTLIDIKV 603
Cdd:cd02009 117 sFEDEFERLFGTPQGLDFEHLAKAYGLEYRRVSSLDELEQALESALAQDGPHVIEVKT 174
|
|
| TPP_ComE |
cd03372 |
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins ... |
470-606 |
2.35e-05 |
|
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins similar to Methanococcus jannaschii sulfopyruvate decarboxylase beta subunit (ComE). M. jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits, which catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. ComDE requires TPP and divalent metal cation cofactors.
Pssm-ID: 239469 [Multi-domain] Cd Length: 179 Bit Score: 45.36 E-value: 2.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 470 MGYEVSAALGVKLAEPqREVYAMVGDGAFMMLHSELVTSIQEGAK-VNVLLFDNMANGCINNlQMEHGMDSfgtefrfrs 548
Cdd:cd03372 44 MGLASSIGLGLALAQP-RKVIVIDGDGSLLMNLGALATIAAEKPKnLIIVVLDNGAYGSTGN-QPTHAGKK--------- 112
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 655997487 549 aengqlngglvpVDFAAIAAGYGCK-TWRVTTLDELKIALEAAQRETVstLIDIKVLPK 606
Cdd:cd03372 113 ------------TDLEAVAKACGLDnVATVASEEAFEKAVEQALDGPS--FIHVKIKPG 157
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
413-590 |
8.24e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 45.63 E-value: 8.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 413 ALTDSTLTQSNVLGILNETLPQEAVIV--AAAGSLPGDLQRvwrTRAPNAYHVEYGYSCMGYEVSAALGVKLAEPQREVY 490
Cdd:PRK12474 335 ALPKGALNSLGVAQLIAHRTPDQAIYAdeALTSGLFFDMSY---DRARPHTHLPLTGGSIGQGLPLAAGAAVAAPDRKVV 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655997487 491 AMVGDGAFMMLHSELVTSIQEGAKVNVLLFDNMANGCINNLQMEHGMDSFGTE-FRFRSAENGQLNgglvpvdFAAIAAG 569
Cdd:PRK12474 412 CPQGDGGAAYTMQALWTMARENLDVTVVIFANRSYAILNGELQRVGAQGAGRNaLSMLDLHNPELN-------WMKIAEG 484
|
170 180
....*....|....*....|.
gi 655997487 570 YGCKTWRVTTLDELKIALEAA 590
Cdd:PRK12474 485 LGVEASRATTAEEFSAQYAAA 505
|
|
| PRK06163 |
PRK06163 |
hypothetical protein; Provisional |
432-500 |
1.28e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 235721 [Multi-domain] Cd Length: 202 Bit Score: 43.67 E-value: 1.28e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 655997487 432 LPQEAVIVAAAGSLPGDLqrvWRT--RAPNAYHVeygySCMGYEVSAALGVKLAEPQREVYAMVGDGAFMM 500
Cdd:PRK06163 26 LKDEEAVIGGIGNTNFDL---WAAgqRPQNFYML----GSMGLAFPIALGVALAQPKRRVIALEGDGSLLM 89
|
|
| |
