|
Name |
Accession |
Description |
Interval |
E-value |
| cyclopro_CfaB |
NF040703 |
C17 cyclopropane fatty acid synthase CfaB; |
4-397 |
3.22e-152 |
|
C17 cyclopropane fatty acid synthase CfaB;
Pssm-ID: 468667 [Multi-domain] Cd Length: 393 Bit Score: 436.35 E-value: 3.22e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 4 MLTSLEKRLAGLPVRVTVELPNGQH--LGPEQgDVRLSLRSQAALLALSQGQIGTLASAVVEGWVDLQGSMRDIMAAASA 81
Cdd:NF040703 1 MLAQLPPALRNLQLPLRLRLWDGKQldLGPSP-RVTLVVKDPSLLSQLTHPSLDLLGSAYVEGRLDLEGPIMEVIRVGDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 82 L---LHSDPVGSTAPRWStrlvermrsmalHTLERDAMQVQYHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAK 158
Cdd:NF040703 80 LsqaLLGDDDEAPPERTA------------HDKATDAAAISYHYDLSNDFYALWLDPDMVYSCAYFETGTEDLAQAQQAK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 159 LDHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIAREGLQQQVEVALCDYRELK-DAPF 237
Cdd:NF040703 148 LRHLCRKLRLQPGERLLDVGCGWGGLARFAAREFGVEVFGITLSKEQLKLARERVAAEGLQDRVQLELLDYRDLPqDGRF 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 238 DKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALIHGITAGGTRNRQVGAGMGDFIGRYIFPGGELMHVSAVLNDMADA 317
Cdd:NF040703 228 DKVVSVGMFEHVGHANLPLYCQRLFGAVRPGGLVMNHGITARHTDGRPVGRGAGEFIGRYVFPHGELPHLATITASISEA 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 318 GLEMVDTENLRPHYARTLWAWSDALEAQLDTALQVLcetlhreqAERSLKAYRLYLAGCAMGFEHGWTALHQMLAT--HP 395
Cdd:NF040703 308 GLEVVDVESLRLHYARTLEHWSARLEARLDEAARLV--------PERALRIWRLYLAGCAYGFARGWINLHQILAVkpLA 379
|
..
gi 929044184 396 DG 397
Cdd:NF040703 380 DG 381
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
111-389 |
1.63e-121 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 353.94 E-value: 1.63e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 111 LERDAMQVQYHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAKLDHICRKLRLQAGERLLDIGCGWGGLIVWAAK 190
Cdd:pfam02353 2 KTRDAENIQAHYDLSNDFFALFLDPTMTYSCAYFERPDMTLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRRAAE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 191 HYGVKAKGITLSRNQHQYVRELIAREGLQQQVEVALCDYRELkDAPFDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGL 270
Cdd:pfam02353 82 RYDVNVVGLTLSKNQYKLARKRVAAEGLARKVEVLLQDYRDF-DEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPPGGL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 271 ALIHGITAGGTRNRQVGAGMGDFIGRYIFPGGELMHVSAVLNDMADAGLEMVDTENLRPHYARTLWAWSDALEAQLDTAL 350
Cdd:pfam02353 161 MLLHTITGLHPDETSERGLPLKFIDKYIFPGGELPSISMIVESSSEAGFTVEDVESLRPHYAKTLDLWAENLQANKDEAI 240
|
250 260 270
....*....|....*....|....*....|....*....
gi 929044184 351 qvlcetlhREQAERSLKAYRLYLAGCAMGFEHGWTALHQ 389
Cdd:pfam02353 241 --------ALQSEEFYRMWMLYLTGCAVAFRIGYIDVHQ 271
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
120-275 |
3.65e-79 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 241.37 E-value: 3.65e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 120 YHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAKLDHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAKGI 199
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFEDPDDTLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 929044184 200 TLSRNQHQYVRELIAREGLQQQVEVALCDYREL-KDAPFDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALIHG 275
Cdd:COG2230 81 TLSPEQLEYARERAAEAGLADRVEVRLADYRDLpADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLHT 157
|
|
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
93-380 |
4.88e-74 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 236.28 E-value: 4.88e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 93 PRWSTRLVERMRS--MALHTLERdAMQV-QYHYDLSDAFYALWLDPLRVYSCAYYREPDmTLAQAQEAKLDHICRKLRLQ 169
Cdd:PRK11705 89 PHHLKDTLRILRArlFNLQSKKR-AWIVgKEHYDLGNDLFEAMLDPRMQYSCGYWKDAD-TLEEAQEAKLDLICRKLQLK 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 170 AGERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIAreGLqqQVEVALCDYRELKDaPFDKLVSVGMFEHV 249
Cdd:PRK11705 167 PGMRVLDIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERCA--GL--PVEIRLQDYRDLNG-QFDRIVSVGMFEHV 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 250 GRVNLPAYFEAVRRLLQPGGLALIHgiTAGGTRNRQvgagMGD-FIGRYIFPGGELMHVSavlnDMADAgLE----MVDT 324
Cdd:PRK11705 242 GPKNYRTYFEVVRRCLKPDGLFLLH--TIGSNKTDT----NVDpWINKYIFPNGCLPSVR----QIAQA-SEglfvMEDW 310
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 929044184 325 ENLRPHYARTLWAWSDALEAQLDTALQVLCETLHReqaerslkAYRLYLAGCAMGF 380
Cdd:PRK11705 311 HNFGADYDRTLMAWHENFEAAWPELADNYSERFYR--------MWRYYLLSCAGAF 358
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
118-389 |
9.16e-70 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 221.95 E-value: 9.16e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 118 VQYHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAKLDHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAK 197
Cdd:NF040660 8 VQAHYDLSDDFFALFLDPTQTYSCAYFERDDMTLEEAQIAKIDLALGKLNLEPGMTLLDIGCGWGATMRRAVEKYDVNVV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 198 GITLSRNQHQYVRELIAREGLQQQVEVALCDYRELkDAPFDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALIHGIT 277
Cdd:NF040660 88 GLTLSKNQAAHVQQVLDEIDTPRSRRVLLQGWEEF-DEPVDRIVSIGAFEHFGHERYDDFFKRAYNILPADGRMLLHTIT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 278 aGGTRNRQVGAGMG---------DFIGRYIFPGGELMHVSAVLNDMADAGLEMVDTENLRPHYARTLWAWSDALEAQLDT 348
Cdd:NF040660 167 -GLHRKEMHERGLPltmelarfiKFIVTEIFPGGRLPSIEMVVEHAEKAGFTVTRVQSLQPHYARTLDLWADALQAHKDE 245
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 929044184 349 ALQVlcetlhreQAERSLKAYRLYLAGCAMGFEHGWTALHQ 389
Cdd:NF040660 246 AIAI--------QSEEVYERYMKYLTGCAKLFRDGYIDVNQ 278
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
173-274 |
1.05e-11 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 61.29 E-value: 1.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 173 RLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRElIAREGLQQQVEVALCDYREL---KDAPFDKLVSVGMFEHV 249
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARK-AAAALLADNVEVLKGDAEELppeADESFDVIISDPPLHHL 79
|
90 100
....*....|....*....|....*
gi 929044184 250 GRvNLPAYFEAVRRLLQPGGLALIH 274
Cdd:cd02440 80 VE-DLARFLEEARRLLKPGGVLVLT 103
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
172-273 |
6.60e-08 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 52.80 E-value: 6.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 172 ERLLDIGCGWG-GLIVWAAKHYGVKAKGITLSRNQHQYVRELIAREGLQQQVEVAlcdYRELKDAPF-DKLVSVGMFEHV 249
Cdd:smart00828 1 KRVLDFGCGYGsDLIDLAERHPHLQLHGYTISPEQAEVGRERIRALGLQGRIRIF---YRDSAKDPFpDTYDLVFGFEVI 77
|
90 100
....*....|....*....|....*
gi 929044184 250 GRV-NLPAYFEAVRRLLQPGGLALI 273
Cdd:smart00828 78 HHIkDKMDLFSNISRHLKDGGHLVL 102
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| cyclopro_CfaB |
NF040703 |
C17 cyclopropane fatty acid synthase CfaB; |
4-397 |
3.22e-152 |
|
C17 cyclopropane fatty acid synthase CfaB;
Pssm-ID: 468667 [Multi-domain] Cd Length: 393 Bit Score: 436.35 E-value: 3.22e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 4 MLTSLEKRLAGLPVRVTVELPNGQH--LGPEQgDVRLSLRSQAALLALSQGQIGTLASAVVEGWVDLQGSMRDIMAAASA 81
Cdd:NF040703 1 MLAQLPPALRNLQLPLRLRLWDGKQldLGPSP-RVTLVVKDPSLLSQLTHPSLDLLGSAYVEGRLDLEGPIMEVIRVGDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 82 L---LHSDPVGSTAPRWStrlvermrsmalHTLERDAMQVQYHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAK 158
Cdd:NF040703 80 LsqaLLGDDDEAPPERTA------------HDKATDAAAISYHYDLSNDFYALWLDPDMVYSCAYFETGTEDLAQAQQAK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 159 LDHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIAREGLQQQVEVALCDYRELK-DAPF 237
Cdd:NF040703 148 LRHLCRKLRLQPGERLLDVGCGWGGLARFAAREFGVEVFGITLSKEQLKLARERVAAEGLQDRVQLELLDYRDLPqDGRF 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 238 DKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALIHGITAGGTRNRQVGAGMGDFIGRYIFPGGELMHVSAVLNDMADA 317
Cdd:NF040703 228 DKVVSVGMFEHVGHANLPLYCQRLFGAVRPGGLVMNHGITARHTDGRPVGRGAGEFIGRYVFPHGELPHLATITASISEA 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 318 GLEMVDTENLRPHYARTLWAWSDALEAQLDTALQVLcetlhreqAERSLKAYRLYLAGCAMGFEHGWTALHQMLAT--HP 395
Cdd:NF040703 308 GLEVVDVESLRLHYARTLEHWSARLEARLDEAARLV--------PERALRIWRLYLAGCAYGFARGWINLHQILAVkpLA 379
|
..
gi 929044184 396 DG 397
Cdd:NF040703 380 DG 381
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
111-389 |
1.63e-121 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 353.94 E-value: 1.63e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 111 LERDAMQVQYHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAKLDHICRKLRLQAGERLLDIGCGWGGLIVWAAK 190
Cdd:pfam02353 2 KTRDAENIQAHYDLSNDFFALFLDPTMTYSCAYFERPDMTLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRRAAE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 191 HYGVKAKGITLSRNQHQYVRELIAREGLQQQVEVALCDYRELkDAPFDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGL 270
Cdd:pfam02353 82 RYDVNVVGLTLSKNQYKLARKRVAAEGLARKVEVLLQDYRDF-DEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPPGGL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 271 ALIHGITAGGTRNRQVGAGMGDFIGRYIFPGGELMHVSAVLNDMADAGLEMVDTENLRPHYARTLWAWSDALEAQLDTAL 350
Cdd:pfam02353 161 MLLHTITGLHPDETSERGLPLKFIDKYIFPGGELPSISMIVESSSEAGFTVEDVESLRPHYAKTLDLWAENLQANKDEAI 240
|
250 260 270
....*....|....*....|....*....|....*....
gi 929044184 351 qvlcetlhREQAERSLKAYRLYLAGCAMGFEHGWTALHQ 389
Cdd:pfam02353 241 --------ALQSEEFYRMWMLYLTGCAVAFRIGYIDVHQ 271
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
120-275 |
3.65e-79 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 241.37 E-value: 3.65e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 120 YHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAKLDHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAKGI 199
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFEDPDDTLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 929044184 200 TLSRNQHQYVRELIAREGLQQQVEVALCDYREL-KDAPFDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALIHG 275
Cdd:COG2230 81 TLSPEQLEYARERAAEAGLADRVEVRLADYRDLpADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLHT 157
|
|
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
93-380 |
4.88e-74 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 236.28 E-value: 4.88e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 93 PRWSTRLVERMRS--MALHTLERdAMQV-QYHYDLSDAFYALWLDPLRVYSCAYYREPDmTLAQAQEAKLDHICRKLRLQ 169
Cdd:PRK11705 89 PHHLKDTLRILRArlFNLQSKKR-AWIVgKEHYDLGNDLFEAMLDPRMQYSCGYWKDAD-TLEEAQEAKLDLICRKLQLK 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 170 AGERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIAreGLqqQVEVALCDYRELKDaPFDKLVSVGMFEHV 249
Cdd:PRK11705 167 PGMRVLDIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERCA--GL--PVEIRLQDYRDLNG-QFDRIVSVGMFEHV 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 250 GRVNLPAYFEAVRRLLQPGGLALIHgiTAGGTRNRQvgagMGD-FIGRYIFPGGELMHVSavlnDMADAgLE----MVDT 324
Cdd:PRK11705 242 GPKNYRTYFEVVRRCLKPDGLFLLH--TIGSNKTDT----NVDpWINKYIFPNGCLPSVR----QIAQA-SEglfvMEDW 310
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 929044184 325 ENLRPHYARTLWAWSDALEAQLDTALQVLCETLHReqaerslkAYRLYLAGCAMGF 380
Cdd:PRK11705 311 HNFGADYDRTLMAWHENFEAAWPELADNYSERFYR--------MWRYYLLSCAGAF 358
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
118-389 |
9.16e-70 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 221.95 E-value: 9.16e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 118 VQYHYDLSDAFYALWLDPLRVYSCAYYREPDMTLAQAQEAKLDHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAK 197
Cdd:NF040660 8 VQAHYDLSDDFFALFLDPTQTYSCAYFERDDMTLEEAQIAKIDLALGKLNLEPGMTLLDIGCGWGATMRRAVEKYDVNVV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 198 GITLSRNQHQYVRELIAREGLQQQVEVALCDYRELkDAPFDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALIHGIT 277
Cdd:NF040660 88 GLTLSKNQAAHVQQVLDEIDTPRSRRVLLQGWEEF-DEPVDRIVSIGAFEHFGHERYDDFFKRAYNILPADGRMLLHTIT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 278 aGGTRNRQVGAGMG---------DFIGRYIFPGGELMHVSAVLNDMADAGLEMVDTENLRPHYARTLWAWSDALEAQLDT 348
Cdd:NF040660 167 -GLHRKEMHERGLPltmelarfiKFIVTEIFPGGRLPSIEMVVEHAEKAGFTVTRVQSLQPHYARTLDLWADALQAHKDE 245
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 929044184 349 ALQVlcetlhreQAERSLKAYRLYLAGCAMGFEHGWTALHQ 389
Cdd:NF040660 246 AIAI--------QSEEVYERYMKYLTGCAKLFRDGYIDVNQ 278
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
175-269 |
7.48e-20 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 83.77 E-value: 7.48e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 175 LDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIAREGLqqQVEVALCDYREL--KDAPFDKLVSVGMFEHVGRV 252
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGL--NVEFVQGDAEDLpfPDGSFDLVVSSGVLHHLPDP 79
|
90
....*....|....*..
gi 929044184 253 NLPAYFEAVRRLLQPGG 269
Cdd:pfam13649 80 DLEAALREIARVLKPGG 96
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
160-273 |
4.44e-15 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 71.95 E-value: 4.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 160 DHICRKLRLQAGERLLDIGCGWGGLIVWAAKHyGVKAKGITLSRNQHQYVRELIAREGLqqQVEVALCDYREL--KDAPF 237
Cdd:COG2226 12 EALLAALGLRPGARVLDLGCGTGRLALALAER-GARVTGVDISPEMLELARERAAEAGL--NVEFVVGDAEDLpfPDGSF 88
|
90 100 110
....*....|....*....|....*....|....*.
gi 929044184 238 DKLVSVGMFEHVGrvNLPAYFEAVRRLLQPGGLALI 273
Cdd:COG2226 89 DLVISSFVLHHLP--DPERALAEIARVLKPGGRLVV 122
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
154-275 |
8.25e-15 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 72.64 E-value: 8.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 154 AQEAKLDHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIAREGLQQqVEVALCDYRELK 233
Cdd:COG0500 10 LLPGLAALLALLERLPKGGRVLDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAAKAGLGN-VEFLVADLAELD 88
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 929044184 234 DAP---FDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALIHG 275
Cdd:COG0500 89 PLPaesFDLVVAFGVLHHLPPEEREALLRELARALKPGGVLLLSA 133
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
149-273 |
1.56e-13 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 66.96 E-value: 1.56e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 149 MTLAQAQEAKLDHICRKLR--LQAGERLLDIGCGWGGLIVWAAKHyGVKAKGITLSRNQHQYVRELIAREGlqqqVEVAL 226
Cdd:COG2227 1 MSDPDARDFWDRRLAALLArlLPAGGRVLDVGCGTGRLALALARR-GADVTGVDISPEALEIARERAAELN----VDFVQ 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 929044184 227 CDYREL--KDAPFDKLVSVGMFEHVGrvNLPAYFEAVRRLLQPGGLALI 273
Cdd:COG2227 76 GDLEDLplEDGSFDLVICSEVLEHLP--DPAALLRELARLLKPGGLLLL 122
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
173-274 |
1.05e-11 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 61.29 E-value: 1.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 173 RLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRElIAREGLQQQVEVALCDYREL---KDAPFDKLVSVGMFEHV 249
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARK-AAAALLADNVEVLKGDAEELppeADESFDVIISDPPLHHL 79
|
90 100
....*....|....*....|....*
gi 929044184 250 GRvNLPAYFEAVRRLLQPGGLALIH 274
Cdd:cd02440 80 VE-DLARFLEEARRLLKPGGVLVLT 103
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
175-273 |
1.39e-11 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 60.37 E-value: 1.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 175 LDIGCGWGGLIVWAAKhYGVKAKGITLSRNQHQYVRELIAREGLQQQVevalCDYREL--KDAPFDKLVSVGMFEHVgrV 252
Cdd:pfam08241 1 LDVGCGTGLLTELLAR-LGARVTGVDISPEMLELAREKAPREGLTFVV----GDAEDLpfPDNSFDLVLSSEVLHHV--E 73
|
90 100
....*....|....*....|.
gi 929044184 253 NLPAYFEAVRRLLQPGGLALI 273
Cdd:pfam08241 74 DPERALREIARVLKPGGILII 94
|
|
| PLN02336 |
PLN02336 |
phosphoethanolamine N-methyltransferase |
165-273 |
5.13e-09 |
|
phosphoethanolamine N-methyltransferase
Pssm-ID: 177970 [Multi-domain] Cd Length: 475 Bit Score: 57.84 E-value: 5.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 165 KLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRE-LIAREGLqQQVEVALCDYRELKDAPFDKLVSV 243
Cdd:PLN02336 261 KLDLKPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALErAIGRKCS-VEFEVADCTKKTYPDNSFDVIYSR 339
|
90 100 110
....*....|....*....|....*....|
gi 929044184 244 GMFEHVGrvNLPAYFEAVRRLLQPGGLALI 273
Cdd:PLN02336 340 DTILHIQ--DKPALFRSFFKWLKPGGKVLI 367
|
|
| Methyltransf_23 |
pfam13489 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
166-322 |
8.93e-09 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 404385 [Multi-domain] Cd Length: 162 Bit Score: 54.36 E-value: 8.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 166 LRLQAGERLLDIGCGWGGLIVWAAKHyGVKAKGITLSRNQHQYVRELIAREGLQQQVEVAlcdyrelKDAPFDKLVSVGM 245
Cdd:pfam13489 18 PKLPSPGRVLDFGCGTGIFLRLLRAQ-GFSVTGVDPSPIAIERALLNVRFDQFDEQEAAV-------PAGKFDVIVAREV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 246 FEHVGrvNLPAYFEAVRRLLQPGGLALIHgitaggTRNRQVGAGMGDFIGRYIFPGGELMHV---SAVLNDMADAGLEMV 322
Cdd:pfam13489 90 LEHVP--DPPALLRQIAALLKPGGLLLLS------TPLASDEADRLLLEWPYLRPRNGHISLfsaRSLKRLLEEAGFEVV 161
|
|
| PLN02244 |
PLN02244 |
tocopherol O-methyltransferase |
144-249 |
5.69e-08 |
|
tocopherol O-methyltransferase
Pssm-ID: 215135 [Multi-domain] Cd Length: 340 Bit Score: 54.37 E-value: 5.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 144 YREPDMTLAQAQEAKLDHICRKLRLqAG---------ERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIA 214
Cdd:PLN02244 84 YYDPGASRGDHRQAQIRMIEESLAW-AGvpdddekrpKRIVDVGCGIGGSSRYLARKYGANVKGITLSPVQAARANALAA 162
|
90 100 110
....*....|....*....|....*....|....*..
gi 929044184 215 REGLQQQVEVALCDYREL--KDAPFDKLVSVGMFEHV 249
Cdd:PLN02244 163 AQGLSDKVSFQVADALNQpfEDGQFDLVWSMESGEHM 199
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
172-273 |
6.60e-08 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 52.80 E-value: 6.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 172 ERLLDIGCGWG-GLIVWAAKHYGVKAKGITLSRNQHQYVRELIAREGLQQQVEVAlcdYRELKDAPF-DKLVSVGMFEHV 249
Cdd:smart00828 1 KRVLDFGCGYGsDLIDLAERHPHLQLHGYTISPEQAEVGRERIRALGLQGRIRIF---YRDSAKDPFpDTYDLVFGFEVI 77
|
90 100
....*....|....*....|....*
gi 929044184 250 GRV-NLPAYFEAVRRLLQPGGLALI 273
Cdd:smart00828 78 HHIkDKMDLFSNISRHLKDGGHLVL 102
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
175-270 |
2.07e-07 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 48.90 E-value: 2.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 175 LDIGCGWGGLIVWAAKHY-GVKAKGITLSRNQ-HQYVRELIAREGLQ-QQVEVALCDYRELKDAPFDKLVSVGMFEHVGr 251
Cdd:pfam08242 1 LEIGCGTGTLLRALLEALpGLEYTGLDISPAAlEAARERLAALGLLNaVRVELFQLDLGELDPGSFDVVVASNVLHHLA- 79
|
90
....*....|....*....
gi 929044184 252 vNLPAYFEAVRRLLQPGGL 270
Cdd:pfam08242 80 -DPRAVLRNIRRLLKPGGV 97
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
170-273 |
5.35e-07 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 47.51 E-value: 5.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 170 AGERLLDIGCGWGGLIVWAAKHY-GVKAKGITLSrnqhqyvRELI--AREGLqQQVEVALCDYRELK-DAPFDKLVSVGM 245
Cdd:COG4106 1 PPRRVLDLGCGTGRLTALLAERFpGARVTGVDLS-------PEMLarARARL-PNVRFVVADLRDLDpPEPFDLVVSNAA 72
|
90 100
....*....|....*....|....*...
gi 929044184 246 FEHVGrvNLPAYFEAVRRLLQPGGLALI 273
Cdd:COG4106 73 LHWLP--DHAALLARLAAALAPGGVLAV 98
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
153-270 |
7.28e-07 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 49.23 E-value: 7.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 153 QAQEAKLDHICRKLRLQAGERLLDIGCGwGGLIVWAAKHYGVKAKGITLSRNqhqyVRELIAREGLQQQVEVAlcDYREL 232
Cdd:COG4976 29 EAPALLAEELLARLPPGPFGRVLDLGCG-TGLLGEALRPRGYRLTGVDLSEE----MLAKAREKGVYDRLLVA--DLADL 101
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 929044184 233 K--DAPFDKLVSVGMFEHVGrvNLPAYFEAVRRLLQPGGL 270
Cdd:COG4976 102 AepDGRFDLIVAADVLTYLG--DLAAVFAGVARALKPGGL 139
|
|
| TrmR |
COG4122 |
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ... |
166-294 |
3.19e-06 |
|
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443298 Cd Length: 173 Bit Score: 47.10 E-value: 3.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 166 LRLQAGERLLDIGCGWG-GLIVWAAkhyGVKAKG--ITLSRNQ--HQYVRELIAREGLQQQVEVALCD----YRELKDAP 236
Cdd:COG4122 12 ARLLGAKRILEIGTGTGySTLWLAR---ALPDDGrlTTIEIDPerAAIARENFARAGLADRIRLILGDalevLPRLADGP 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 929044184 237 FDkLVSVGmfehVGRVNLPAYFEAVRRLLQPGGL-----ALIHGITAGGTRNRQVGAGMGDFI 294
Cdd:COG4122 89 FD-LVFID----ADKSNYPDYLELALPLLRPGGLivadnVLWHGRVADPARRDPSTRAIREFN 146
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
170-273 |
5.15e-06 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 46.26 E-value: 5.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 170 AGERLLDIGCGWGGLIVWAAKHYGVKAK--GITLSRNQHQYVRELIAREGLqQQVEVALCDYREL----KDAPFDKLVSV 243
Cdd:pfam13847 3 KGMRVLDLGCGTGHLSFELAEELGPNAEvvGIDISEEAIEKARENAQKLGF-DNVEFEQGDIEELpellEDDKFDVVISN 81
|
90 100 110
....*....|....*....|....*....|
gi 929044184 244 GMFEHVGrvNLPAYFEAVRRLLQPGGLALI 273
Cdd:pfam13847 82 CVLNHIP--DPDKVLQEILRVLKPGGRLII 109
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
160-273 |
8.12e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 46.85 E-value: 8.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 160 DHICRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAK--GITLSRNQHQYVRELIAREGLQQQVEVALCDYRELKDAPF 237
Cdd:PRK08317 9 ARTFELLAVQPGDRVLDVGCGPGNDARELARRVGPEGRvvGIDRSEAMLALAKERAAGLGPNVEFVRGDADGLPFPDGSF 88
|
90 100 110
....*....|....*....|....*....|....*.
gi 929044184 238 DKLVSVGMFEHVGrvNLPAYFEAVRRLLQPGGLALI 273
Cdd:PRK08317 89 DAVRSDRVLQHLE--DPARALAEIARVLRPGGRVVV 122
|
|
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
163-273 |
1.75e-05 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 45.91 E-value: 1.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 163 CRKLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAK--GITLSRNQHQYVRELIAREGLQQQVEVALCDYREL--KDAPFD 238
Cdd:PRK00216 44 IKWLGVRPGDKVLDLACGTGDLAIALAKAVGKTGEvvGLDFSEGMLAVGREKLRDLGLSGNVEFVQGDAEALpfPDNSFD 123
|
90 100 110
....*....|....*....|....*....|....*...
gi 929044184 239 kLVSVGmFehvGRVNLPAYFEAVR---RLLQPGGLALI 273
Cdd:PRK00216 124 -AVTIA-F---GLRNVPDIDKALRemyRVLKPGGRLVI 156
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
166-273 |
9.33e-05 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 43.25 E-value: 9.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 166 LRLQAGERLLDIGCGWGGLIVWAAKHYGVKAkgITLSRNQH---QYVRELIAREGLqQQVEVALCD-YRELKDAPFDKLV 241
Cdd:COG2813 45 LPEPLGGRVLDLGCGYGVIGLALAKRNPEAR--VTLVDVNAravELARANAAANGL-ENVEVLWSDgLSGVPDGSFDLIL 121
|
90 100 110
....*....|....*....|....*....|....*.
gi 929044184 242 SVGMFeHVGRVNLP----AYFEAVRRLLQPGGLALI 273
Cdd:COG2813 122 SNPPF-HAGRAVDKevahALIADAARHLRPGGELWL 156
|
|
| Qor |
COG0604 |
NADPH:quinone reductase or related Zn-dependent oxidoreductase [Energy production and ... |
164-345 |
1.59e-04 |
|
NADPH:quinone reductase or related Zn-dependent oxidoreductase [Energy production and conversion, General function prediction only];
Pssm-ID: 440369 [Multi-domain] Cd Length: 322 Bit Score: 43.21 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 164 RKLRLQAGERLLDIGCGwGGLIVWA---AKHYGVKAKGITLSRNQHQYVRELIAREGLqqqvevalcDYRE------LKD 234
Cdd:COG0604 133 DRGRLKPGETVLVHGAA-GGVGSAAvqlAKALGARVIATASSPEKAELLRALGADHVI---------DYREedfaerVRA 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 235 APFDKLVSVGmFEHVGRvnlpAYFEAVRRLLQPGG-LALIhgitaGGTRNRQVGAGMGDFIGRYIFPGGELM--HVSAVL 311
Cdd:COG0604 203 LTGGRGVDVV-LDTVGG----DTLARSLRALAPGGrLVSI-----GAASGAPPPLDLAPLLLKGLTLTGFTLfaRDPAER 272
|
170 180 190
....*....|....*....|....*....|....
gi 929044184 312 NDMADAGLEMVDTENLRPHYARTLwAWSDALEAQ 345
Cdd:COG0604 273 RAALAELARLLAAGKLRPVIDRVF-PLEEAAEAH 305
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
173-269 |
7.01e-04 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 40.27 E-value: 7.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 173 RLLDIGCGWGGLIVWAAKHYGVKAkgITLSRNQHQYVRelIAREGLQ----QQVEVALCD-YRELKDAPFDKLVSVGMFe 247
Cdd:pfam05175 34 KVLDLGCGAGVLGAALAKESPDAE--LTMVDINARALE--SARENLAanglENGEVVASDvYSGVEDGKFDLIISNPPF- 108
|
90 100
....*....|....*....|....*.
gi 929044184 248 HVGRVNLP----AYFEAVRRLLQPGG 269
Cdd:pfam05175 109 HAGLATTYnvaqRFIADAKRHLRPGG 134
|
|
| COG4076 |
COG4076 |
Predicted RNA methylase [General function prediction only]; |
171-269 |
1.30e-03 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 443253 [Multi-domain] Cd Length: 230 Bit Score: 40.02 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 171 GERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQHQYVRELIAREGLQQQVEVALCDYRELK-DAPFDKLVS----VGM 245
Cdd:COG4076 36 GDVVLDIGTGSGLLSMLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSDRITVINADATDLDlPEKADVIISemldTAL 115
|
90 100
....*....|....*....|....*
gi 929044184 246 F-EHVgrvnLPAYFEAVRRLLQPGG 269
Cdd:COG4076 116 LdEGQ----VPILNHARKRLLKPGG 136
|
|
| MetW |
pfam07021 |
Methionine biosynthesis protein MetW; This family consists of several bacterial and one ... |
168-241 |
1.92e-03 |
|
Methionine biosynthesis protein MetW; This family consists of several bacterial and one archaeal methionine biosynthesis MetW proteins. Biosynthesis of methionine from homoserine in Pseudomonas putida takes place in three steps. The first step is the acylation of homoserine to yield an acyl-L-homoserine. This reaction is catalyzed by the products of the metXW genes and is equivalent to the first step in enterobacteria, gram-positive bacteria and fungi, except that in these microorganizms the reaction is catalyzed by a single polypeptide (the product of the metA gene in Escherichia coli and the met5 gene product in Neurospora crassa). In Pseudomonas putida, as in gram-positive bacteria and certain fungi, the second and third steps are a direct sulfhydrylation that converts the O-acyl-L-homoserine into homocysteine and further methylation to yield methionine. The latter reaction can be mediated by either of the two methionine synthetases present in the cells.
Pssm-ID: 399779 Cd Length: 193 Bit Score: 39.36 E-value: 1.92e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 929044184 168 LQAGERLLDIGCGWGGLIVWAAKHYGVKAKGITLSRNQhqyVRELIAReGL---QQQVEVALCDYrelKDAPFDKLV 241
Cdd:pfam07021 11 IPPGSRVLDLGCGDGTLLYLLKEEKGVDGYGIELDAAG---VAECVAK-GLyviQGDLDEGLEHF---PDKSFDYVI 80
|
|
| COG4627 |
COG4627 |
Predicted SAM-depedendent methyltransferase [General function prediction only]; |
232-273 |
4.25e-03 |
|
Predicted SAM-depedendent methyltransferase [General function prediction only];
Pssm-ID: 443666 [Multi-domain] Cd Length: 161 Bit Score: 37.92 E-value: 4.25e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 929044184 232 LKDAPFDKLVSVGMFEHVGRVNLPAYFEAVRRLLQPGGLALI 273
Cdd:COG4627 42 FPDNSVDAIYSSHVLEHLDYEEAPLALKECYRVLKPGGILRI 83
|
|
| cbiT |
PRK00377 |
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional |
165-277 |
4.54e-03 |
|
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
Pssm-ID: 234740 Cd Length: 198 Bit Score: 38.24 E-value: 4.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929044184 165 KLRLQAGERLLDIGCGWGGLIVWAAKHYGVKAK--GITLSRNQHQYVRELIAREGLQQQVEVALCDYRELKDAPFDKLVS 242
Cdd:PRK00377 35 KLRLRKGDMILDIGCGTGSVTVEASLLVGETGKvyAVDKDEKAINLTRRNAEKFGVLNNIVLIKGEAPEILFTINEKFDR 114
|
90 100 110
....*....|....*....|....*....|....*
gi 929044184 243 VgmFEHVGRVNLPAYFEAVRRLLQPGGLALIHGIT 277
Cdd:PRK00377 115 I--FIGGGSEKLKEIISASWEIIKKGGRIVIDAIL 147
|
|
| |
