|
Name |
Accession |
Description |
Interval |
E-value |
| IolD |
COG3962 |
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism ... |
1-644 |
0e+00 |
|
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism [Carbohydrate transport and metabolism];
Pssm-ID: 443162 [Multi-domain] Cd Length: 622 Bit Score: 1184.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 1 MQTIKLTVAQALVKFLDNQYIEIDGKEIKFVHGIAAIFGHGNVLGIGQALEQDPGSLRLYQGRNEQGMAHLAIGFAKQHK 80
Cdd:COG3962 2 MKTIRLTVAQALVRFLANQYVERDGEEQPLFAGVFGIFGHGNVAGLGQALEQDPDELPTYQGRNEQGMAHAAIAYAKQKN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 81 RQQIIACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQPHDLSISTNDAFRAVSKYWDRVLRPE 160
Cdd:COG3962 82 RRRIMACTSSIGPGATNMVTAAALATANRLPVLLLPGDTFATRQPDPVLQQLEHFHDPTISVNDAFRPVSRYWDRITRPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 161 QLMSACINAMRVLTDPAETGAVTIALPQDVQAEAYDFPVSFLQKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGV 240
Cdd:COG3962 162 QLMSALPRAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPPPDPAELARAVELIRAAKRPLIIAGGGV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 241 RYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFQNP 320
Cdd:COG3962 242 RYSEATEALRAFAEATGIPVAETQAGKGALPWDHPLNLGGIGVTGTLAANALAAEADLVIGVGTRLQDFTTGSKTLFANP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 321 DVAFLNINIARFDAYKLDGVQVTADAKQSINALIDKLPP-GYKTQWGDAIKQAKADFADELQRLRQVKFtdgfvpeindn 399
Cdd:COG3962 322 DVRFVNINVARFDAYKHDALPVVADAREGLEALTEALAGwRYPAAWTDEAAELKAEWDAEVDRLYAPTN----------- 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 400 ldhdavyaefikltNSCLTQSQVLGIVNETIDNSAVIVGAAGSLPGDLQRTWLSKSEDSYHLEYGYSCMGYEVNAAVGVK 479
Cdd:COG3962 391 --------------GGLPTQAQVIGAVNEAAGPDDIVVCAAGSLPGDLHKLWRTRDPGTYHVEYGYSCMGYEIAGGLGVK 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 480 IAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFRNPETNQLNGSLIPV 559
Cdd:COG3962 457 LAEPDREVYVMVGDGSYLMLNSELVTSVQEGKKIIVVLLDNHGFGCINRLQMSTGSQSFGTELRDRDTETGRLDGGLLPV 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 560 DFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLPKTMAHGYGCWWHVGVADVSTSERIQQAHQRSKEQLA 639
Cdd:COG3962 537 DFAANAASLGAKAYRVTTIAELRAALERAKAADRTTVIVIKTDPKTMTPGGGSWWDVGVAEVSERESVRAARAEYEEARA 616
|
....*
gi 2006413104 640 KARKY 644
Cdd:COG3962 617 KQRRY 621
|
|
| myo_inos_iolD |
TIGR04377 |
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5 ... |
5-643 |
0e+00 |
|
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase (iolD), represent one of eight enzymes in a pathway converting myo-inositol to acetyl-CoA. IolD hydrolyzes the cyclic molecule 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione to yield 5-deoxy-D-glucuronic acid. TPP is a cofactor. [Energy metabolism, Sugars]
Pssm-ID: 275170 [Multi-domain] Cd Length: 615 Bit Score: 1080.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDNQYIEIDGKEIKFVHGIAAIFGHGNVLGIGQALEQDPGSLRLYQGRNEQGMAHLAIGFAKQHKRQQI 84
Cdd:TIGR04377 1 RLTMAQALVRFLAAQYVERDGEEVPFFAGVFAIFGHGNVAGLGEALEEDPDDLPTYRGRNEQGMAHAAIAYAKQKNRRRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 85 IACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQPHDLSISTNDAFRAVSKYWDRVLRPEQLMS 164
Cdd:TIGR04377 81 MACTSSIGPGATNMVTAAALATVNRLPVLLLPGDTFATRQPDPVLQQLEDFSDLTVSVNDAFRPVSRYFDRITRPEQLMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 165 ACINAMRVLTDPAETGAVTIALPQDVQAEAYDFPVSFLQKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQ 244
Cdd:TIGR04377 161 ALPNAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPEPDPAELERAVAAIRAAKKPLIVAGGGVHYSE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 245 ACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFQNPDVAF 324
Cdd:TIGR04377 241 AGEALAAFAEKHGIPVAETQAGKGALPWDHPLNLGAIGVTGTLAANALAAEADLVIAVGTRLQDFTTASKTLFQNPDVRF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 325 LNINIARFDAYKLDGVQVTADAKQSINALIDKLpPGYKTQ--WGDAIKQAKADFADELQRLRQVKFTDGFVPeindnldh 402
Cdd:TIGR04377 321 VNINVARFDAYKHDALPLVADARAGLEALSEAL-GGYRADsaWAAEAAAAKAAWDAEVDRLYAAEYTAGGLP-------- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 403 davyaefikltnsclTQSQVLGIVNETIDNSAVIVGAAGSLPGDLQRTWLSKSEDSYHLEYGYSCMGYEVNAAVGVKIAQ 482
Cdd:TIGR04377 392 ---------------TQAEVIGAVNRAAGPDDVVVCAAGSLPGDLHKLWRTRDPGGYHMEYGYSCMGYEIAGGLGVKLAE 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 483 PEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFrnPETNQLNGSLIPVDFA 562
Cdd:TIGR04377 457 PDREVYVMVGDGSYLMLNSELATSVQEGKKIIVVLLDNRGFGCINNLQMSTGGASFNTELRY--EDTGRLDGGLLPVDFA 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 563 MCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLPKTMAHGYGCWWHVGVADVSTSERIQQAHQRSKEQLAKAR 642
Cdd:TIGR04377 535 AHAAALGAKTYKVTTIAELEAALARAKAADRTTLIVIDTDPKTMTEGYGSWWDVGVAEVSERESVRKAREEYEEAKKAQR 614
|
.
gi 2006413104 643 K 643
Cdd:TIGR04377 615 K 615
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
419-623 |
1.40e-112 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 336.20 E-value: 1.40e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 419 QSQVLGIVNETIDNSAVIVGAAGSLPGDLQRTWLSKSEDSYHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLM 498
Cdd:cd02003 1 QTEVLGALNEAIGDDDVVINAAGSLPGDLHKLWRARTPGGYHLEYGYSCMGYEIAAGLGAKLAKPDREVYVLVGDGSYLM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 499 SHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFRNPETNQLNGSLIPVDFAMCAAAYGCKTYKVTTE 578
Cdd:cd02003 81 LHSEIVTAVQEGLKIIIVLFDNHGFGCINNLQESTGSGSFGTEFRDRDQESGQLDGALLPVDFAANARSLGARVEKVKTI 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2006413104 579 DELRKALADAKQQTVSTLIDIKVLPKTMAHGYGCWWHVGVADVST 623
Cdd:cd02003 161 EELKAALAKAKASDRTTVIVIKTDPKSMTPGYGSWWDVGVAEVSE 205
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
5-603 |
6.43e-100 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 315.56 E-value: 6.43e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDNqyieidgkeikfvHGIAAIFGH--GNVLGIGQALEQDPGsLRLYQGRNEQGMAHLAIGFAKQHKRq 82
Cdd:COG0028 2 KMTGADALVEALEA-------------EGVETVFGVpgGAILPLYDALRRQSG-IRHILVRHEQGAAFMADGYARATGK- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 83 qIIACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQPhdlsistnDAFRAVSKYWDRVLRPEQL 162
Cdd:COG0028 67 -PGVCLVTSGPGATNLVTGLADAYMDSVPVLAITGQVPTSLIGRGAFQEVDQV--------GLFRPITKWSYLVTDPEDL 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 163 MSACINAMRVLTDPaETGAVTIALPQDVQAEAYDFPVSFLQKRVHRiERTPPTQEMLADAVKLITSKKKPLIICGGGVRY 242
Cdd:COG0028 138 PEVLRRAFRIATSG-RPGPVVLDIPKDVQAAEAEEEPAPPELRGYR-PRPAPDPEAIEEAAELLAAAKRPVILAGGGARR 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 243 SQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFqNPDV 322
Cdd:COG0028 216 AGAAEELRALAERLGAPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALAEADLVLAVGARFDDRVTGNWDEF-APDA 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 323 AFLNINIarfDAYKLD-----GVQVTADAKQSINALIDKLPP--GYKTQWGDAIKQAKADFADELQRLRQVKFTDGFVPE 395
Cdd:COG0028 295 KIIHIDI---DPAEIGknypvDLPIVGDAKAVLAALLEALEPraDDRAAWLARIAAWRAEYLAAYAADDGPIKPQRVIAA 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 396 INDNLDHDAVYaefikltnscltqsqvlgivneTIDNSAVIVGAAGSLPGDLQRTWLSksedsyhlEYGYSCMGYEVNAA 475
Cdd:COG0028 372 LREALPDDAIV----------------------VTDVGQHQMWAARYLRFRRPRRFLT--------SGGLGTMGYGLPAA 421
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 476 VGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGN-GMGSYGTEFRfrnpetnqlng 554
Cdd:COG0028 422 IGAKLARPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNNGGLGMVRQWQELFyGGRYSGTDLP----------- 490
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2006413104 555 sliPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLP 603
Cdd:COG0028 491 ---NPDFAKLAEAFGAKGERVETPEELEAALEEALASDGPALIDVRVDP 536
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
5-607 |
7.24e-52 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 187.53 E-value: 7.24e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDNqyieidgkeikfvHGIAAIFG--HGNVLGIGQALEQDPGSLRLYQGRNEQGMAHLAIGFAKQHKRq 82
Cdd:PRK08266 3 TMTGGEAIVAGLVA-------------HGVDTVFGlpGAQLYWLFDALYKAGDRIRVIHTRHEQAAGYMAFGYARSTGR- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 83 qIIACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVfasrqPDPVLQQ-----IEQPHDLSIstndaFRAVSKYWDRVL 157
Cdd:PRK08266 69 -PGVCSVVPGPGVLNAGAALLTAYGCNSPVLCLTGQI-----PSALIGKgrghlHEMPDQLAT-----LRSFTKWAERIE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 158 RPEQ---LMSACINAMRvltdPAETGAVTIALPQDV-QAEAydfPVSFLQKrVHRIERTPPTQEMLADAVKLITSKKKPL 233
Cdd:PRK08266 138 HPSEapaLVAEAFQQML----SGRPRPVALEMPWDVfGQRA---PVAAAPP-LRPAPPPAPDPDAIAAAAALIAAAKNPM 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 234 IICGGGVRysQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELnvggvGETgCLAANRLAKEADLIIGIGTRYTDFTTSS 313
Cdd:PRK08266 210 IFVGGGAA--GAGEEIRELAEMLQAPVVAFRSGRGIVSDRHPL-----GLN-FAAAYELWPQTDVVIGIGSRLELPTFRW 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 314 KWIFQNPDVAFLNINIARFDAYKLDgVQVTADAKQSINALIDKLPPGYKTQWG--DAIKQAKADFADELQRLR-QVKFTD 390
Cdd:PRK08266 282 PWRPDGLKVIRIDIDPTEMRRLKPD-VAIVADAKAGTAALLDALSKAGSKRPSrrAELRELKAAARQRIQAVQpQASYLR 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 391 GfvpeINDNLDHDAVYAEFikltnscLTQsqvlgivnetidnsaviVGAAG--SLPGDLQRTWLSKsedsyhleyGYS-C 467
Cdd:PRK08266 361 A----IREALPDDGIFVDE-------LSQ-----------------VGFASwfAFPVYAPRTFVTC---------GYQgT 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 468 MGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSY-GTEfrFRN 546
Cdd:PRK08266 404 LGYGFPTALGAKVANPDRPVVSITGDGGFMFGVQELATAVQHNIGVVTVVFNNNAYGNVRRDQKRRFGGRVvASD--LVN 481
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2006413104 547 PetnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLPKTMA 607
Cdd:PRK08266 482 P------------DFVKLAESFGVAAFRVDSPEELRAALEAALAHGGPVLIEVPVPRGSEA 530
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
33-585 |
6.36e-51 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 185.41 E-value: 6.36e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGH--GNVLGIGQALEQDPGsLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNRI 110
Cdd:PRK07282 24 GVDTIFGYpgGAVLPLYDAIYNFEG-IRHILARHEQGALHEAEGYAKSTGKLGVAVVTS--GPGATNAITGIADAMSDSV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 111 PLLLLPGDVFASRQPDPVLQQIEQphdLSISTndafrAVSKYWDRVLRPEQLMSACINAMRVLTDpAETGAVTIALPQDV 190
Cdd:PRK07282 101 PLLVFTGQVARAGIGKDAFQEADI---VGITM-----PITKYNYQIRETADIPRIITEAVHIATT-GRPGPVVIDLPKDV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 191 QAEAYDFPVSFLQKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAI 270
Cdd:PRK07282 172 SALETDFIYDPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVVTTLLGQGTI 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 271 VSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIF-QNPDVAFLNINIARFDAYKLDGVQVTADAKQS 349
Cdd:PRK07282 252 ATSHPLFLGMGGMHGSYAANIAMTEADFMINIGSRFDDRLTGNPKTFaKNAKVAHIDIDPAEIGKIIKTDIPVVGDAKKA 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 350 INALIDKlpPGYKTQWGDAIKQAKADFAdelqRLRQVKFTdgfvpeindnlDHDAVYAEFIKLtnscltqsqvlgiVNET 429
Cdd:PRK07282 332 LQMLLAE--PTVHNNTEKWIEKVTKDKN----RVRSYDKK-----------ERVVQPQAVIER-------------IGEL 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 430 IDNSAVIVGAAGSlpgdlQRTWLS-----KSEDSYHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELV 504
Cdd:PRK07282 382 TNGDAIVVTDVGQ-----HQMWAAqyypyQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVILFVGDGGFQMTNQELA 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 505 TSIQEGKKINVVLFDNMANGCINNLQVGngmgsygtefrFRNPETNQLNGSLIPvDFAMCAAAYGCKTYKVTTEDELRKA 584
Cdd:PRK07282 457 ILNIYKVPIKVVMLNNHSLGMVRQWQES-----------FYEGRTSESVFDTLP-DFQLMAQAYGIKHYKFDNPETLAQD 524
|
.
gi 2006413104 585 L 585
Cdd:PRK07282 525 L 525
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
87-601 |
4.25e-50 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 182.72 E-value: 4.25e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 87 CTSSVGPGAANMVTAAATATSNRIPLLLLPGDVfasrqpdPVL---QQIEQPHDLSistnDAFRAVSKYWDRVLRPEQLM 163
Cdd:PRK08322 67 CLSTLGPGATNLVTGVAYAQLGGMPMVAITGQK-------PIKrskQGSFQIVDVV----AMMAPLTKWTRQIVSPDNIP 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 164 SACINAMRVltdpAET---GAVTIALPQDVQAEAYDFPVsflqKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGV 240
Cdd:PRK08322 136 EVVREAFRL----AEEerpGAVHLELPEDIAAEETDGKP----LPRSYSRRPYASPKAIERAAEAIQAAKNPLILIGAGA 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 241 RYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGetgcLAA----NRLAKEADLIIGIG---TRYTDFttss 313
Cdd:PRK08322 208 NRKTASKALTEFVDKTGIPFFTTQMGKGVIPETHPLSLGTAG----LSQgdyvHCAIEHADLIINVGhdvIEKPPF---- 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 314 KWifqNPDVAFLNINIARFDA-----YKLDgVQVTADAKQSINALIDKLPPGYKTQWGDAIKqAKADFADELQRLRQvkf 388
Cdd:PRK08322 280 FM---NPNGDKKVIHINFLPAevdpvYFPQ-VEVVGDIANSLWQLKERLADQPHWDFPRFLK-IREAIEAHLEEGAD--- 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 389 TDGFvPEINDNLDHDaVYaefikltnscltqsQVLG---IVneTIDNSAVIVGAAGSLPGDLQRTWLsksedsyhLEYGY 465
Cdd:PRK08322 352 DDRF-PMKPQRIVAD-LR--------------KVMPdddIV--ILDNGAYKIWFARNYRAYEPNTCL--------LDNAL 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 466 SCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEfrFR 545
Cdd:PRK08322 406 ATMGAGLPSAIAAKLVHPDRKVLAVCGDGGFMMNSQELETAVRLGLPLVVLILNDNAYGMIRWKQENMGFEDFGLD--FG 483
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 2006413104 546 NPetnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:PRK08322 484 NP------------DFVKYAESYGAKGYRVESADDLLPTLEEALAQPGVHVIDCPV 527
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
9-603 |
4.06e-49 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 180.72 E-value: 4.06e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 9 AQALVKFLDNQYIEIdgkeikfvhgiaaIFGH--GNVLGIGQALEQDpgSLRLYQGRNEQGMAHLAIGFAKQHKRQQIia 86
Cdd:PRK06276 4 AEAIIKALEAEGVKI-------------IFGYpgGALLPFYDALYDS--DLIHILTRHEQAAAHAADGYARASGKVGV-- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 87 CTSSVGPGAANMVTAAATATSNRIPLLLLPGDVfasrqpdpvlqqieqPHDLsIStNDAFRAV---------SKYWDRVL 157
Cdd:PRK06276 67 CVATSGPGATNLVTGIATAYADSSPVIALTGQV---------------PTKL-IG-NDAFQEIdalgifmpiTKHNFQIK 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 158 RPEQLMSACINAMRVltdpAETG---AVTIALPQDVQAEAYDFPVSFLQKRVHRIERTP-----PTQemLADAVKLITSK 229
Cdd:PRK06276 130 KPEEIPEIFRAAFEI----AKTGrpgPVHIDLPKDVQEGELDLEKYPIPAKIDLPGYKPttfghPLQ--IKKAAELIAEA 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 230 KKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDF 309
Cdd:PRK06276 204 ERPVILAGGGVIISGASEELIELSELVKIPVCTTLMGKGAFPEDHPLALGMVGMHGTKAANYSVTESDVLIAIGCRFSDR 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 310 TTSSKWIFQnPDVAFLNINIARFDAYKLDGVQV--TADAKQSINALIDKLPPGY---KTQWGDAIKQAKA------DFAD 378
Cdd:PRK06276 284 TTGDISSFA-PNAKIIHIDIDPAEIGKNVRVDVpiVGDAKNVLRDLLAELMKKEiknKSEWLERVKKLKKesiprmDFDD 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 379 ELQRLRQVkftdgfVPEINDNLDHDAVYAEFIKLTNscLTQSQVLgivnetidnsavivgAAGSLPGDLQRTWLSKSeds 458
Cdd:PRK06276 363 KPIKPQRV------IKELMEVLREIDPSKNTIITTD--VGQNQMW---------------MAHFFKTSAPRSFISSG--- 416
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 459 yhleyGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQvgNGMgsY 538
Cdd:PRK06276 417 -----GLGTMGFGFPAAIGAKVAKPDANVIAITGDGGFLMNSQELATIAEYDIPVVICIFDNRTLGMVYQWQ--NLY--Y 487
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2006413104 539 GTefrfRNPETNqLNGSliPvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLP 603
Cdd:PRK06276 488 GK----RQSEVH-LGET--P-DFVKLAESYGVKADRVEKPDEIKEALKEAIKSGEPYLLDIIIDP 544
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
3-601 |
2.29e-48 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 178.04 E-value: 2.29e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 3 TIKLTVAQALVKFLDNQyieidgkeikfvhGIAAIFGH--GNVLGIGQALEQdpGSLRLYQGRNEQGMAHLAIGFAKQHK 80
Cdd:PRK06048 5 TEKMTGARAIIKCLEKE-------------GVEVIFGYpgGAIIPVYDELYD--SDLRHILVRHEQAAAHAADGYARATG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 81 RQQIiaCTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQ-----IEQP---HD-LSISTNDAFRAVSK 151
Cdd:PRK06048 70 KVGV--CVATSGPGATNLVTGIATAYMDSVPIVALTGQVPRSMIGNDAFQEaditgITMPitkHNyLVQDAKDLPRIIKE 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 152 --YWDRVLRPeqlmsacinamrvltdpaetGAVTIALPQDVQAEAYDFpvsFLQKRVHrIERTPPT----QEMLADAVKL 225
Cdd:PRK06048 148 afHIASTGRP--------------------GPVLIDLPKDVTTAEIDF---DYPDKVE-LRGYKPTykgnPQQIKRAAEL 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 226 ITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTR 305
Cdd:PRK06048 204 IMKAERPIIYAGGGVISSNASEELVELAETIPAPVTTTLMGIGAIPTEHPLSLGMLGMHGTKYANYAIQESDLIIAVGAR 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 306 YTDFTTSSKWIFQnPDVAFLNINIARFDAYKLDGVQV--TADAKQSINALIDKLPPGYKTQWGDAIKQAKADFAdelqrL 383
Cdd:PRK06048 284 FDDRVTGKLASFA-PNAKIIHIDIDPAEISKNVKVDVpiVGDAKQVLKSLIKYVQYCDRKEWLDKINQWKKEYP-----L 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 384 RQVKFTDGFVPEIndnldhdavyaefikltnscltqsqVLGIVNETIDNsAVIVGAAGSlpgdlQRTWLS-----KSEDS 458
Cdd:PRK06048 358 KYKEREDVIKPQY-------------------------VIEQIYELCPD-AIIVTEVGQ-----HQMWAAqyfkyKYPRT 406
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 459 YHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQvgngmgsy 538
Cdd:PRK06048 407 FITSGGLGTMGYGFPAAIGAKVGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNGYLGMVRQWQ-------- 478
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2006413104 539 gTEFRFRNPETNQLNGSlipVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:PRK06048 479 -ELFYDKRYSHTCIKGS---VDFVKLAEAYGALGLRVEKPSEVRPAIEEAVASDRPVVIDFIV 537
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
2-603 |
2.39e-48 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 178.36 E-value: 2.39e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 2 QTIKLTVAQALVKFLDNQYIEIdgkeikfvhgIAAIFGhGNVLGIGQALEQDpGSLRLYQGRNEQGMAHLAIGFAKQHKR 81
Cdd:PRK08155 9 TRKRFTGAELIVRLLERQGIRI----------VTGIPG-GAILPLYDALSQS-TQIRHILARHEQGAGFIAQGMARTTGK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 82 QQIiaCTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQpHDLSIStndafraVSKYWDRVLRPEQ 161
Cdd:PRK08155 77 PAV--CMACSGPGATNLVTAIADARLDSIPLVCITGQVPASMIGTDAFQEVDT-YGISIP-------ITKHNYLVRDIEE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 162 LMSACINAMRVLTDpAETGAVTIALPQDVQAEAYDFPVsfLQKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVR 241
Cdd:PRK08155 147 LPQVISDAFRIAQS-GRPGPVWIDIPKDVQTAVIELEA--LPAPAEKDAAPAFDEESIRDAAAMINAAKRPVLYLGGGVI 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 242 YSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFqNPD 321
Cdd:PRK08155 224 NSGAPARARELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGARSTNYILQEADLLIVLGARFDDRAIGKTEQF-CPN 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 322 VAFLNINI--ARFDAYKLDGVQVTADAKQSINALIDKLPPGYKTQWGDAIKQAKADFADELqrlrqvkftdgfvPEINDN 399
Cdd:PRK08155 303 AKIIHVDIdrAELGKIKQPHVAIQADVDDVLAQLLPLVEAQPRAEWHQLVADLQREFPCPI-------------PKADDP 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 400 LDHdavYAeFIKLTNSCLtqsqvlgivnetiDNSAVI---VG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCMGYE 471
Cdd:PRK08155 370 LSH---YG-LINAVAACV-------------DDNAIIttdVGqhqmwTAQAYPLNRPRQWLTSG--------GLGTMGFG 424
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 472 VNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQ-VGNGMGSYGTEFRFRnpetn 550
Cdd:PRK08155 425 LPAAIGAALANPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIILMNNEALGLVHQQQsLFYGQRVFAATYPGK----- 499
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 2006413104 551 qlngslipVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDI------KVLP 603
Cdd:PRK08155 500 --------INFMQIAAGFGLETCDLNNEADPQAALQEAINRPGPALIHVridaeeKVYP 550
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
6-609 |
1.29e-46 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 172.85 E-value: 1.29e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 6 LTVAQALVKFLDNqyieidgkeikfvHGIAAIFGhgnvlgIgqaleqdPG--SLRLYQG-----------RNEQGMAHLA 72
Cdd:PRK07524 2 TTCGEALVRLLEA-------------YGVETVFG------I-------PGvhTVELYRGlagsgirhvtpRHEQGAGFMA 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 73 IGFAKQHKRQQIiaCTSSVGPGAANMVTAAATATSNRIPLLLLPGdVFASRQ-----------PDpvlQQieqphdlsis 141
Cdd:PRK07524 56 DGYARVSGKPGV--CFIITGPGMTNIATAMGQAYADSIPMLVISS-VNRRASlgkgrgklhelPD---QR---------- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 142 tnDAFRAVSKYWDRVLRPEQLMSACINAMRVLtDPAETGAVTIALPQDVQAEAYDFPVSflqKRVHRIERTPPTQEMLAD 221
Cdd:PRK07524 120 --AMVAGVAAFSHTLMSAEDLPEVLARAFAVF-DSARPRPVHIEIPLDVLAAPADHLLP---APPTRPARPGPAPAALAQ 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 222 AVKLITSKKKPLIICGGGVRysQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGvgeTGCLAANR-LAKEADLII 300
Cdd:PRK07524 194 AAERLAAARRPLILAGGGAL--AAAAALRALAERLDAPVALTINAKGLLPAGHPLLLGA---SQSLPAVRaLIAEADVVL 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 301 GIGTRY--TDFTTSSKWIFQNPDvAFLNINIarfDAYKLDG-----VQVTADAKQSINALIDKLPPGYKT-QWGdaikqa 372
Cdd:PRK07524 269 AVGTELgeTDYDVYFDGGFPLPG-ELIRIDI---DPDQLARnyppaLALVGDARAALEALLARLPGQAAAaDWG------ 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 373 kadfADELQRLRQvkftdgfvpeindnldhdAVYAEFIKLTnscLTQSQVLGIVNETIDNsAVIVGA------AGSLPGD 446
Cdd:PRK07524 339 ----AARVAALRQ------------------ALRAEWDPLT---AAQVALLDTILAALPD-AIFVGDstqpvyAGNLYFD 392
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 447 L--QRTWLSKSEdsyhleyGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANG 524
Cdd:PRK07524 393 AdaPRRWFNAST-------GYGTLGYGLPAAIGAALGAPERPVVCLVGDGGLQFTLPELASAVEADLPLIVLLWNNDGYG 465
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 525 CINNLQVGNGMGSYGTEfrFRNPetnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVlPK 604
Cdd:PRK07524 466 EIRRYMVARDIEPVGVD--PYTP------------DFIALARAFGCAAERVADLEQLQAALRAAFARPGPTLIEVDQ-AC 530
|
....*
gi 2006413104 605 TMAHG 609
Cdd:PRK07524 531 WFAAV 535
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
32-601 |
4.28e-45 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 169.85 E-value: 4.28e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 32 HGIAAIFGH--GNVLGIGQAL---EQDpGSLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATAT 106
Cdd:PRK07418 32 HGVKHIFGYpgGAILPIYDELykaEAE-GWLKHILVRHEQGAAHAADGYARATGKVGVCFGTS--GPGATNLVTGIATAQ 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 107 SNRIPLLLLPGDVfasrqPDPvlqqieqphdlSISTnDAFRA----------VSKYWdrVLR-PEQLMSACINAMRVltd 175
Cdd:PRK07418 109 MDSVPMVVITGQV-----PRP-----------AIGT-DAFQEtdifgitlpiVKHSY--VVRdPSDMARIVAEAFHI--- 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 176 pAETG---AVTIALPQDVQAEAYDF----PVSFLQKRVHRIERTPPTQemLADAVKLITSKKKPLIICGGGVRYSQACRS 248
Cdd:PRK07418 167 -ASSGrpgPVLIDIPKDVGQEEFDYvpvePGSVKPPGYRPTVKGNPRQ--INAALKLIEEAERPLLYVGGGAISAGAHAE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 249 LQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTD--------FTTSSKWIFQNP 320
Cdd:PRK07418 244 LKELAERFQIPVTTTLMGKGAFDEHHPLSVGMLGMHGTAYANFAVTECDLLIAVGARFDDrvtgkldeFASRAKVIHIDI 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 321 DVAFLNINiarfdayKLDGVQVTADAKQSINALIDKL----PPGYKTQWGDAIKQAKADFAdeLQrlrqvkftdgfVPEi 396
Cdd:PRK07418 324 DPAEVGKN-------RRPDVPIVGDVRKVLVKLLERSleptTPPRTQAWLERINRWKQDYP--LV-----------VPP- 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 397 ndnlDHDAVYAEfikltnscltqsQVLGIVNETIDNSAVI--VG-----AAGSL---PgdlqRTWLSKSedsyhleyGYS 466
Cdd:PRK07418 383 ----YEGEIYPQ------------EVLLAVRDLAPDAYYTtdVGqhqmwAAQFLrngP----RRWISSA--------GLG 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 467 CMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQvgngmGSYGTEfrfRN 546
Cdd:PRK07418 435 TMGFGMPAAMGVKVALPDEEVICIAGDASFLMNIQELGTLAQYGINVKTVIINNGWQGMVRQWQ-----ESFYGE---RY 506
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 2006413104 547 PETNQLNGslIPvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:PRK07418 507 SASNMEPG--MP-DFVKLAEAFGVKGMVISERDQLKDAIAEALAHDGPVLIDVHV 558
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
53-610 |
4.40e-44 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 165.82 E-value: 4.40e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 53 DPGSLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNRIPLLLLPGDV---FASRQpdpVL 129
Cdd:PRK08199 43 DETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFVTR--GPGATNASIGVHTAFQDSTPMILFVGQVardFRERE---AF 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 130 QQIEqphdlsisTNDAFRAVSKyW----DRVLR-PEqLMSaciNAMRVLTD--PaetGAVTIALPQDVQAEAYDFPVsfl 202
Cdd:PRK08199 118 QEID--------YRRMFGPMAK-WvaeiDDAARiPE-LVS---RAFHVATSgrP---GPVVLALPEDVLSETAEVPD--- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 203 qKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVG 282
Cdd:PRK08199 179 -APPYRRVAAAPGAADLARLAELLARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACAFRRQDLFDNRHPNYAGDLG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 283 etgcLAAN-RLA---KEADLIIGIGTRYTDFTTSSKWIFQNPDvaflniniarfDAYKLdgVQVTADAK---------QS 349
Cdd:PRK08199 258 ----LGINpALAariREADLVLAVGTRLGEVTTQGYTLLDIPV-----------PRQTL--VHVHPDAEelgrvyrpdLA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 350 INA-------LIDKLPPGYKTQWGDAIKQAKADFADELQRLRQVKFTDgfvpeindnldhdavyaefikltnscltQSQV 422
Cdd:PRK08199 321 IVAdpaafaaALAALEPPASPAWAEWTAAAHADYLAWSAPLPGPGAVQ----------------------------LGEV 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 423 LGIVNETIDNSAVIVGAAGSLPGDLQRTWLSKSedsYHLEYGYSC--MGYEVNAAVGVKIAQPEREVYALVGDGAFLMSH 500
Cdd:PRK08199 373 MAWLRERLPADAIITNGAGNYATWLHRFFRFRR---YRTQLAPTSgsMGYGLPAAIAAKLLFPERTVVAFAGDGCFLMNG 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 501 SELVTSIQEGKKINVVLFDNmangcinnlqvgngmGSYGT-------EF-------RFRNPetnqlngslipvDFAMCAA 566
Cdd:PRK08199 450 QELATAVQYGLPIIVIVVNN---------------GMYGTirmhqerEYpgrvsgtDLTNP------------DFAALAR 502
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 2006413104 567 AYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLPKTMAHGY 610
Cdd:PRK08199 503 AYGGHGETVERTEDFAPAFERALASGKPALIEIRIDPEAITPTA 546
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
63-601 |
6.69e-44 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 165.66 E-value: 6.69e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 63 RNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQphdLSISt 142
Cdd:PRK08527 48 RHEQAAVHAADGYARASGKVGVAIVTS--GPGFTNAVTGLATAYMDSIPLVLISGQVPNSLIGTDAFQEIDA---VGIS- 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 143 ndafRAVSKYWDRVLRPEQLMsacinamRVLTDP---AETG---AVTIALPQDVQAEAYDFpvsFLQKRVhRIERTPPT- 215
Cdd:PRK08527 122 ----RPCVKHNYLVKSIEELP-------RILKEAfyiARSGrpgPVHIDIPKDVTATLGEF---EYPKEI-SLKTYKPTy 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 216 ---QEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRL 292
Cdd:PRK08527 187 kgnSRQIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTGIPAVETLMARGVLRSDDPLLLGMLGMHGSYAANMA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 293 AKEADLIIGIGTRYTDFTTSSKWIF-QNPDVAFLNINIARFDAYKLDGVQVTADAKQSINALIDKLppgyktqwGDAIKQ 371
Cdd:PRK08527 267 MSECDLLISLGARFDDRVTGKLSEFaKHAKIIHVDIDPSSISKIVNADYPIVGDLKNVLKEMLEEL--------KEENPT 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 372 AKADFADELQRLRQVkftdgfvpeindnldHDAVYAEfiklTNSCLTQSQVLGIVNETIDNSAVI---VG-----AAGSL 443
Cdd:PRK08527 339 TYKEWREILKRYNEL---------------HPLSYED----SDEVLKPQWVIERVGELLGDDAIIstdVGqhqmwVAQFY 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 444 PGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKK-INVVLFDNMA 522
Cdd:PRK08527 400 PFNYPRQLATSG--------GLGTMGYGLPAALGAKLAVPDKVVINFTGDGSILMNIQELMTAVEYKIPvINIILNNNFL 471
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2006413104 523 nGCINNLQvgngmgSYGTEFRFrnpetNQLNGSLIPvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:PRK08527 472 -GMVRQWQ------TFFYEERY-----SETDLSTQP-DFVKLAESFGGIGFRVTTKEEFDKALKEALESDKVALIDVKI 537
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
32-603 |
4.47e-43 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 163.72 E-value: 4.47e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 32 HGIAAIFGH--GNVLGIGQALE--QDPGSLRLYQGRNEQGMAHLAIGFAKQhkRQQIIACTSSVGPGAANMVTAAATATS 107
Cdd:CHL00099 23 HGVKHIFGYpgGAILPIYDELYawEKKGLIKHILVRHEQGAAHAADGYARS--TGKVGVCFATSGPGATNLVTGIATAQM 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 108 NRIPLLLLPGDVfaSRQpdpvlqqieqphdlSISTnDAFRAVSKY--------WDRVLRPEQLMSACINAMRVLTDPAET 179
Cdd:CHL00099 101 DSVPLLVITGQV--GRA--------------FIGT-DAFQEVDIFgitlpivkHSYVVRDARDISRIVAEAFYIAKHGRP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 180 GAVTIALPQDVQAEAYDFPVSFLQKRVHRIE----RTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEK 255
Cdd:CHL00099 164 GPVLIDIPKDVGLEKFDYYPPEPGNTIIKILgcrpIYKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAEL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 256 FGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFQ-NPDVAFLNINIARFDA 334
Cdd:CHL00099 244 YKIPVTTTLMGKGIFDEDHPLCLGMLGMHGTAYANFAVSECDLLIALGARFDDRVTGKLDEFAcNAQVIHIDIDPAEIGK 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 335 YKLDGVQVTADAKQSINALI------DKLPPGYKTQ-WGDAIKQAKADFADELQRLRQVKFTDGFVPEINdNLDHDAVY- 406
Cdd:CHL00099 324 NRIPQVAIVGDVKKVLQELLellknsPNLLESEQTQaWRERINRWRKEYPLLIPKPSTSLSPQEVINEIS-QLAPDAYFt 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 407 ----------AEFIKLtnscltqsqvlgivnetidnsavivgaagslpgdLQRTWLSKSedsyhleyGYSCMGYEVNAAV 476
Cdd:CHL00099 403 tdvgqhqmwaAQFLKC----------------------------------KPRKWLSSA--------GLGTMGYGLPAAI 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 477 GVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQvgngMGSYGTEFRFRNPETNQlngsl 556
Cdd:CHL00099 441 GAQIAHPNELVICISGDASFQMNLQELGTIAQYNLPIKIIIINNKWQGMVRQWQ----QAFYGERYSHSNMEEGA----- 511
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 2006413104 557 iPvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLP 603
Cdd:CHL00099 512 -P-DFVKLAEAYGIKGLRIKSRKDLKSSLKEALDYDGPVLIDCQVIE 556
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
33-601 |
2.28e-42 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 161.54 E-value: 2.28e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGHGNV--LGIGQALEQD--PGSLRLYQGRNEQGMAHLAIGFAKQHKRQQIiaCTSSVGPGAANMVTAAATATSN 108
Cdd:PRK06456 16 GVKVIFGIPGLsnMQIYDAFVEDlaNGELRHVLMRHEQAAAHAADGYARASGVPGV--CTATSGPGTTNLVTGLITAYWD 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 109 RIPLLLLPGDVfasrqPDPVLQQIE-QPHDlsisTNDAFRAVSKYWDRVLRPEQLMSACINAMRVLTDpAETGAVTIALP 187
Cdd:PRK06456 94 SSPVIAITGQV-----PRSVMGKMAfQEAD----AMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATT-GRPGPVVIDIP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 188 QDVQAEAYDfPVSFLQKRVHRIERTPPT---QEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQ 264
Cdd:PRK06456 164 RDIFYEKME-EIKWPEKPLVKGYRDFPTridRLALKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHIPIVSTF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 265 AGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFQNPDVAFLNINIARFD---AYKLDgVQ 341
Cdd:PRK06456 243 PGKTAIPHDHPLYFGPMGYYGRAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDgekAIKVD-VG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 342 VTADAKQSINALIDKLPPGYKtqwgdaikqaKADFADELQRLRQVKftdgfvpeindnldhdAVYAEFIKLT-NSCLTQS 420
Cdd:PRK06456 322 IYGNAKIILRELIKAITELGQ----------KRDRSAWLKRVKEYK----------------EYYSQFYYTEeNGKLKPW 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 421 QVLGIVNETIDNSAVIVGAAGSLPGDLQRTWLSKSEDSYHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSH 500
Cdd:PRK06456 376 KIMKTIRQALPRDAIVTTGVGQHQMWAEVFWEVLEPRTFLTSSGMGTMGFGLPAAMGAKLARPDKVVVDLDGDGSFLMTG 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 501 SELVTSIQEGKKINVVLFDNMANGCINNLQ-VGNGMGSYGTEFrfrNPETnqlngslipvDFAMCAAAYGCKTYKVTTED 579
Cdd:PRK06456 456 TNLATAVDEHIPVISVIFDNRTLGLVRQVQdLFFGKRIVGVDY---GPSP----------DFVKLAEAFGALGFNVTTYE 522
|
570 580
....*....|....*....|..
gi 2006413104 580 ELRKALADAKQQTVSTLIDIKV 601
Cdd:PRK06456 523 DIEKSLKSAIKEDIPAVIRVPV 544
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
5-588 |
9.85e-42 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 160.15 E-value: 9.85e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDnqyieidgkEIkfvhGIAAIFG--HGNVLGIGQALeQDPGSLRLYQGRNEQGMAHLAIGFAKQHKRQ 82
Cdd:PRK07789 30 RMTGAQAVVRSLE---------EL----GVDVVFGipGGAILPVYDPL-FDSTKVRHVLVRHEQGAGHAAEGYAQATGRV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 83 QIIACTSsvGPGAANMVTAAATATSNRIPLLLLPGDVFASrqpdpvlqqieqphdlSISTnDAFR---------AVSKYW 153
Cdd:PRK07789 96 GVCMATS--GPGATNLVTPIADANMDSVPVVAITGQVGRG----------------LIGT-DAFQeadivgitmPITKHN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 154 DRVLRPEQLMSACINAMRVltdpAET---GAVTIALPQDVQAEAYDF------------PVsflqkrvhrierTPPTQEM 218
Cdd:PRK07789 157 FLVTDADDIPRVIAEAFHI----ASTgrpGPVLVDIPKDALQAQTTFswpprmdlpgyrPV------------TKPHGKQ 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 219 LADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADL 298
Cdd:PRK07789 221 IREAAKLIAAARRPVLYVGGGVIRAEASAELRELAELTGIPVVTTLMARGAFPDSHPQHLGMPGMHGTVAAVAALQRSDL 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 299 IIGIGTRYTDFTTSSKWIFQnPDVAFLNINI--ARFDAYKLDGVQVTADAKQSINALIdklpPGYKTQWGDAIKQAKADF 376
Cdd:PRK07789 301 LIALGARFDDRVTGKLDSFA-PDAKVIHADIdpAEIGKNRHADVPIVGDVKEVIAELI----AALRAEHAAGGKPDLTAW 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 377 ADELQRLRQV------KFTDG-----FVPE-INDNLDHDAVYAefikltnSCLTQSQVLgivnetidnsavivgAAGSLP 444
Cdd:PRK07789 376 WAYLDGWRETyplgydEPSDGslapqYVIErLGEIAGPDAIYV-------AGVGQHQMW---------------AAQFID 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 445 GDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLfdnmang 524
Cdd:PRK07789 434 YEKPRTWLNSG--------GLGTMGYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQELATCAIEGIPIKVAL------- 498
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2006413104 525 cINNlqvgngmGSYG------TEF---RFRNpeTNQLNGSL-IPvDFAMCAAAYGCKTYKVTTEDELRKALADA 588
Cdd:PRK07789 499 -INN-------GNLGmvrqwqTLFyeeRYSN--TDLHTHSHrIP-DFVKLAEAYGCVGLRCEREEDVDAVIEKA 561
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
439-599 |
1.94e-41 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 147.35 E-value: 1.94e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 439 AAGSLPGDLQRTWLSKSEDSYHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLF 518
Cdd:pfam02775 1 DIGCHQMWAAQYYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 519 DNMANGCINNLQVGNGMGSYGTEFRFRNPetnqlngsliPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLID 598
Cdd:pfam02775 81 NNGGYGMTRGQQTPFGGGRYSGPSGKILP----------PVDFAKLAEAYGAKGARVESPEELEEALKEALEHDGPALID 150
|
.
gi 2006413104 599 I 599
Cdd:pfam02775 151 V 151
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
7-603 |
2.56e-41 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 158.39 E-value: 2.56e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 7 TVAQALVKFLDNqyieidgkeikfvHGIAAIFGHGnvLGIGQALEQDPGSLRLYQGRNEQGMAHLAIGFAKQHKRQQIIA 86
Cdd:PRK06112 15 TVAHAIARALKR-------------HGVEQIFGQS--LPSALFLAAEAIGIRQIAYRTENAGGAMADGYARVSGKVAVVT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 87 CTSsvGPGAANMVTAAATATSNRIPLLLLPGDV---FASRQPDPVLQQIEqphdlsistndAFRAVSKYWDRVLRPEQLM 163
Cdd:PRK06112 80 AQN--GPAATLLVAPLAEALKASVPIVALVQDVnrdQTDRNAFQELDHIA-----------LFQSCTKWVRRVTVAERID 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 164 SACINAMRVLTDpAETGAVTIALPQDVQAEAYDFPVSFLQKRVHR--IERTPPTQEMLADAVKLITSKKKPLIICGGGVR 241
Cdd:PRK06112 147 DYVDQAFTAATS-GRPGPVVLLLPADLLTAAAAAPAAPRSNSLGHfpLDRTVPAPQRLAEAASLLAQAQRPVVVAGGGVH 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 242 YSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGEtgCLAANRLAK-------EADLIIGIGTRYTDFTTSSk 314
Cdd:PRK06112 226 ISGASAALAALQSLAGLPVATTNMGKGAVDETHPLSLGVVGS--LMGPRSPGRhlrdlvrEADVVLLVGTRTNQNGTDS- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 315 WIFQNPDVAFLNINI------ARFDAYKLDGvqvtaDAKQSINALIDKLPP-------GYKTQWGDAIKQAKADFADELQ 381
Cdd:PRK06112 303 WSLYPEQAQYIHIDVdgeevgRNYEALRLVG-----DARLTLAALTDALRGrdlaaraGRRAALEPAIAAGREAHREDSA 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 382 RLRQVKFTDgFVPEindnldhdAVYAEFikltnscltQSQVLGIVNETIDNSAVIVGAAGSLPGdlqrtwlSKSEDSYHL 461
Cdd:PRK06112 378 PVALSDASP-IRPE--------RIMAEL---------QAVLTGDTIVVADASYSSIWVANFLTA-------RRAGMRFLT 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 462 EYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNgMGSYGTE 541
Cdd:PRK06112 433 PRGLAGLGWGVPMAIGAKVARPGAPVICLVGDGGFAHVWAELETARRMGVPVTIVVLNNGILGFQKHAETVK-FGTHTDA 511
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2006413104 542 FRFRnpetnqlngsliPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLP 603
Cdd:PRK06112 512 CHFA------------AVDHAAIARACGCDGVRVEDPAELAQALAAAMAAPGPTLIEVITDP 561
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
33-588 |
1.97e-40 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 155.90 E-value: 1.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGH--GNVLGIGQALEQDpgSLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNRI 110
Cdd:PRK06725 29 GVTTVFGYpgGAILPVYDALYES--GLKHILTRHEQAAIHAAEGYARASGKVGVVFATS--GPGATNLVTGLADAYMDSI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 111 PLLLLPGDVFAS-------RQPD------PVLQ---QIEQPHDLSISTNDAFravskYWDRVLRPeqlmsacinamrvlt 174
Cdd:PRK06725 105 PLVVITGQVATPligkdgfQEADvvgitvPVTKhnyQVRDVNQLSRIVQEAF-----YIAESGRP--------------- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 175 dpaetGAVTIALPQDVQAEAYdfpVSFLQKRV----HRIERTP-PTQemLADAVKLITSKKKPLIICGGGVRYSQACRSL 249
Cdd:PRK06725 165 -----GPVLIDIPKDVQNEKV---TSFYNEVVeipgYKPEPRPdSMK--LREVAKAISKAKRPLLYIGGGVIHSGGSEEL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 250 QHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFqNPDVAFLNINI 329
Cdd:PRK06725 235 IEFARENRIPVVSTLMGLGAYPPGDPLFLGMLGMHGTYAANMAVTECDLLLALGVRFDDRVTGKLELF-SPHSKKVHIDI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 330 ARFDAYKLDGVQ--VTADAKQSINALIDKLPPGYKTQWGDAIKQAKADfadelqrlrqvkftdgfvpeindnldhdavYA 407
Cdd:PRK06725 314 DPSEFHKNVAVEypVVGDVKKALHMLLHMSIHTQTDEWLQKVKTWKEE------------------------------YP 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 408 EFIKLTNSCLTQSQVLGIVNETIDNSAVI---VG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVK 479
Cdd:PRK06725 364 LSYKQKESELKPQHVINLVSELTNGEAIVtteVGqhqmwAAHFYKAKNPRTFLTSG--------GLGTMGFGFPAAIGAQ 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 480 IAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQvgngmgsygtEFRFRNPETNQLNGSliPv 559
Cdd:PRK06725 436 LAKEEELVICIAGDASFQMNIQELQTIAENNIPVKVFIINNKFLGMVRQWQ----------EMFYENRLSESKIGS--P- 502
|
570 580
....*....|....*....|....*....
gi 2006413104 560 DFAMCAAAYGCKTYKVTTEDELRKALADA 588
Cdd:PRK06725 503 DFVKVAEAYGVKGLRATNSTEAKQVMLEA 531
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
1-599 |
4.45e-40 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 155.16 E-value: 4.45e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 1 MQTIKLTVAQALVKFLDnqyieidgkeikfVHGIAAIFGHgnvlgIGQALEQ-----DPGSLRLYQGRNEQGMAHLAIGF 75
Cdd:PRK07525 1 MGKMKMTPSEAFVETLQ-------------AHGITHAFGI-----IGSAFMDasdlfPPAGIRFIDVAHEQNAGHMADGY 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 76 AKQHKRQQiiACTSSVGPGAANMVTAAATATSNRIPLLLLpgdvfasrQPDPVLQQIEQPHDLSISTNDAFRAVSKYWDR 155
Cdd:PRK07525 63 TRVTGRMG--MVIGQNGPGITNFVTAVATAYWAHTPVVLV--------TPQAGTKTIGQGGFQEAEQMPMFEDMTKYQEE 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 156 VLRPEQlMSACINamRVLTDP-AETGAVTIALPQD-----VQAEAYdfpvsflqkRVHRIERTPPTQEMLADAVKLITSK 229
Cdd:PRK07525 133 VRDPSR-MAEVLN--RVFDKAkRESGPAQINIPRDyfygvIDVEIP---------QPVRLERGAGGEQSLAEAAELLSEA 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 230 KKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDF 309
Cdd:PRK07525 201 KFPVILSGAGVVLSDAIEECKALAERLDAPVACGYLHNDAFPGSHPLWVGPLGYNGSKAAMELIAKADVVLALGTRLNPF 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 310 TTSSK-----WIfQNPDVAFLNINIARFDAYKLDGVQVTADAKQSINALIDKLPPGYKTQWGDA-----IKQAKADFADE 379
Cdd:PRK07525 281 GTLPQygidyWP-KDAKIIQVDINPDRIGLTKKVSVGICGDAKAVARELLARLAERLAGDAGREerkalIAAEKSAWEQE 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 380 LqrlrqvkftdgfvpeinDNLDH--DAVYAEFIKLTNSCLTQ----SQVL----------GIVNETIDNSAVIVGAagsl 443
Cdd:PRK07525 360 L-----------------SSWDHedDDPGTDWNEEARARKPDymhpRQALreiqkalpedAIVSTDIGNNCSIANS---- 418
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 444 pgdlqrtWLSKSEDSYHLEYGY--SCmGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFdnm 521
Cdd:PRK07525 419 -------YLRFEKGRKYLAPGSfgNC-GYAFPAIIGAKIACPDRPVVGFAGDGAWGISMNEVMTAVRHNWPVTAVVF--- 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 522 angciNNLQVG----NGMGSYgtEFRFRNPETNQlngsliPVDFAMCAAAYGCKTYKVTTEDELRKALADA---KQQTVS 594
Cdd:PRK07525 488 -----RNYQWGaekkNQVDFY--NNRFVGTELDN------NVSYAGIAEAMGAEGVVVDTQEELGPALKRAidaQNEGKT 554
|
....*
gi 2006413104 595 TLIDI 599
Cdd:PRK07525 555 TVIEI 559
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
63-592 |
2.29e-39 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 152.66 E-value: 2.29e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 63 RNEQGMAHLAIGFAKQHKRQQIIACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQP-DPvlqqieqphdlSIS 141
Cdd:PRK06154 61 RTERVAVHMADGYARATSGERVGVFAVQYGPGAENAFGGVAQAYGDSVPVLFLPTGYPRGSTDvAP-----------NFE 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 142 TNDAFRAVSKYWDRVLRPEQLMsaciNAMRVLTDPAETGA---VTIALPQDVQAEayDFPVSFLQKRVHRIERTPPTQEM 218
Cdd:PRK06154 130 SLRNYRHITKWCEQVTLPDEVP----ELMRRAFTRLRNGRpgpVVLELPVDVLAE--ELDELPLDHRPSRRSRPGADPVE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 219 LADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADL 298
Cdd:PRK06154 204 VVEAAALLLAAERPVIYAGQGVLYAQATPELKELAELLEIPVMTTLNGKSAFPEDHPLALGSGGRARPATVAHFLREADV 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 299 IIGIGTRYTDFT-----TSSKWIFQNP-DVAFLNINIARFDAykldgvqVTADAKQSINALIDKLPPGYKTQWGDAikqa 372
Cdd:PRK06154 284 LFGIGCSLTRSYyglpmPEGKTIIHSTlDDADLNKDYPIDHG-------LVGDAALVLKQMIEELRRRVGPDRGRA---- 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 373 kADFADELQRLRQvkftdGFVPEINDNLDHDAVyaefikltnsCLTQSQVLGIVNETIDNSAVIVGA-AGSLPGDLQRTW 451
Cdd:PRK06154 353 -QQVAAEIEAVRA-----AWLAKWMPKLTSDST----------PINPYRVVWELQHAVDIKTVIITHdAGSPRDQLSPFY 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 452 LSKSEDSYhLEYGYSC-MGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNmangcinnlq 530
Cdd:PRK06154 417 VASRPGSY-LGWGKTTqLGYGLGLAMGAKLARPDALVINLWGDAAFGMTGMDFETAVRERIPILTILLNN---------- 485
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2006413104 531 vgNGMGSY-------GTEFRfrnpeTNQLNGslipvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQT 592
Cdd:PRK06154 486 --FSMGGYdkvmpvsTTKYR-----ATDISG-----DYAAIARALGGYGERVEDPEMLVPALLRALRKV 542
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
51-613 |
5.24e-39 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 151.69 E-value: 5.24e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 51 EQDpgSLRLYQGRNEQGMAHLAIGFAKQhkRQQIIACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQ 130
Cdd:PRK08611 40 EQD--KIKFIQVRHEEVAALAAAAYAKL--TGKIGVCLSIGGPGAIHLLNGLYDAKMDHVPVLALAGQVTSDLLGTDFFQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 131 QIEQPhdlsistnDAFRAVSKYWDRVLRPEQLMSACINAMRvlTDPAETGAVTIALPQD-----VQAEAYDFPVSFLQKR 205
Cdd:PRK08611 116 EVNLE--------KMFEDVAVYNHQIMSAENLPEIVNQAIR--TAYEKKGVAVLTIPDDlpaqkIKDTTNKTVDTFRPTV 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 206 VHriertpPTQEMLADAVKLITSKKKPLIICGGGVRysQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETG 285
Cdd:PRK08611 186 PS------PKPKDIKKAAKLINKAKKPVILAGLGAK--HAKEELLAFAEKAKIPIIHTLPAKGIIPDDHPYSLGNLGKIG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 286 CLAANRLAKEADLIIGIGTR--YTDF---TTSSKWIFQNPDvaflNINiARFDAykldGVQVTADAKQSINALIDKLPPG 360
Cdd:PRK08611 258 TKPAYEAMQEADLLIMVGTNypYVDYlpkKAKAIQIDTDPA----NIG-KRYPV----NVGLVGDAKKALHQLTENIKHV 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 361 YKTQWGDAIKQAKADFADELQRLRQVKfTDGFVPE-----INDNLDHDAVYAefIKLTNSCLTQSQVLgivNETIDNSAV 435
Cdd:PRK08611 329 EDRRFLEACQENMAKWWKWMEEDENNA-STPIKPErvmaaIQKIADDDAVLS--VDVGTVTVWSARYL---NLGTNQKFI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 436 IvgaagslpgdlqRTWLSKsedsyhleygyscMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINV 515
Cdd:PRK08611 403 I------------SSWLGT-------------MGCGLPGAIAAKIAFPDRQAIAICGDGGFSMVMQDFVTAVKYKLPIVV 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 516 VLFDNMANGCINNLQVGNGMGSYGTEFrfrnpeTNqlngslipVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVST 595
Cdd:PRK08611 458 VVLNNQQLAFIKYEQQAAGELEYAIDL------SD--------MDYAKFAEACGGKGYRVEKAEELDPAFEEALAQDKPV 523
|
570 580
....*....|....*....|....*...
gi 2006413104 596 LIDIKV------LP----KTMAHGYGCW 613
Cdd:PRK08611 524 IIDVYVdpnaapLPgkivNDEALGYSKW 551
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
33-601 |
5.46e-39 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 151.51 E-value: 5.46e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGH--GNVLGIGQALEQDPGsLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNRI 110
Cdd:PRK08979 18 GVKHIFGYpgGSVLDIYDALHEKSG-IEHILVRHEQAAVHMADGYARATGKVGVVLVTS--GPGATNTITGIATAYMDSI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 111 PLLLLPGDVfasrqpdpvlqqieqPHDLSisTNDAF---------RAVSKYWDRVLRPEQLMSACINAMRVLTDpAETGA 181
Cdd:PRK08979 95 PMVVLSGQV---------------PSNLI--GNDAFqecdmigisRPVVKHSFLVKDAEDIPEIIKKAFYIAST-GRPGP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 182 VTIALPQDVQAEAYDFPVSFLQKRVHRiERTPPTQE---MLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGI 258
Cdd:PRK08979 157 VVIDLPKDCLNPAILHPYEYPESIKMR-SYNPTTSGhkgQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 259 PFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSS--KWIfqnPDVAFLNINIARFDAYK 336
Cdd:PRK08979 236 PVVSTLMGLGAFPGTHKNSLGMLGMHGRYEANMAMHNADLIFGIGVRFDDRTTNNleKYC---PNATILHIDIDPSSISK 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 337 ldGVQVTADAKQSINALIDKLPPGYKTQWGDAIKQAKADFADELQRLRQVKFTDgfVPEINDNLDHDAVYAEFIKLTN-- 414
Cdd:PRK08979 313 --TVRVDIPIVGSADKVLDSMLALLDESGETNDEAAIASWWNEIEVWRSRNCLA--YDKSSERIKPQQVIETLYKLTNgd 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 415 ----SCLTQSQVLgivnetidnsavivgAAGSLPGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQPEREVYAL 490
Cdd:PRK08979 389 ayvaSDVGQHQMF---------------AALYYPFDKPRRWINSG--------GLGTMGFGLPAAMGVKFAMPDETVVCV 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 491 VGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQvgngmgsygtEFRFRNPETNQLNGSlIPvDFAMCAAAYGC 570
Cdd:PRK08979 446 TGDGSIQMNIQELSTALQYDIPVKIINLNNRFLGMVKQWQ----------DMIYQGRHSHSYMDS-VP-DFAKIAEAYGH 513
|
570 580 590
....*....|....*....|....*....|....
gi 2006413104 571 KTYKVTTEDELRKALADA---KQQTVstLIDIKV 601
Cdd:PRK08979 514 VGIRISDPDELESGLEKAlamKDRLV--FVDINV 545
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
32-591 |
8.56e-39 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 151.16 E-value: 8.56e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 32 HGIAAIFGH--GNVLGIGQALeQDPGSLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNR 109
Cdd:PRK07979 17 QGVKQVFGYpgGAVLDIYDAL-HTVGGIDHVLVRHEQAAVHMADGLARATGEVGVVLVTS--GPGATNAITGIATAYMDS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 110 IPLLLLPGDVFASRQPDPVLQQIEQphdLSIStndafRAVSKYWDRVLRPEQLMSACINAMrVLTDPAETGAVTIALPQD 189
Cdd:PRK07979 94 IPLVVLSGQVATSLIGYDAFQECDM---VGIS-----RPVVKHSFLVKQTEDIPQVLKKAF-WLAASGRPGPVVVDLPKD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 190 VQAEAYDFPVSFLQKRVHRiERTPPTQE---MLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAG 266
Cdd:PRK07979 165 ILNPANKLPYVWPESVSMR-SYNPTTQGhkgQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPVVSSLMG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 267 KSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTS--SKWIfqnPDVAFLNINIARFDAYKL--DGVQV 342
Cdd:PRK07979 244 LGAFPATHRQSLGMLGMHGTYEANMTMHNADVIFAVGVRFDDRTTNnlAKYC---PNATVLHIDIDPTSISKTvtADIPI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 343 TADAKQSINALIDKLPPGYKTQWGDAIKqakadfaDELQRLRQVKFTD--GFVPEiNDNLDHDAVYAEFIKLTNscltqs 420
Cdd:PRK07979 321 VGDARQVLEQMLELLSQESAHQPLDEIR-------DWWQQIEQWRARQclKYDTH-SEKIKPQAVIETLWRLTK------ 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 421 qvlGIVNETIDNSAVIVGAAGSLPGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSH 500
Cdd:PRK07979 387 ---GDAYVTSDVGQHQMFAALYYPFDKPRRWINSG--------GLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNI 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 501 SELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFRNPetnqlngslipvDFAMCAAAYGCKTYKVTTEDE 580
Cdd:PRK07979 456 QELSTALQYELPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLP------------DFVRLAEAYGHVGIQISHPDE 523
|
570
....*....|.
gi 2006413104 581 LRKALADAKQQ 591
Cdd:PRK07979 524 LESKLSEALEQ 534
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
219-353 |
1.21e-38 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 139.24 E-value: 1.21e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 219 LADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADL 298
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALEEADL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2006413104 299 IIGIGTRYTDFTTSSKWIFQNPDVAFLNINIARFDAYKLDGVQVT--ADAKQSINAL 353
Cdd:pfam00205 81 VLAVGARFDDIRTTGKLPEFAPDAKIIHIDIDPAEIGKNYPVDVPivGDAKETLEAL 137
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
5-601 |
5.75e-38 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 148.91 E-value: 5.75e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDNQyieidgkeikfvhGIAAIFGH--GNVLGIGQALeQDPGSLRLYQGRNEQGMAHLAIGFAKQHKRQ 82
Cdd:PRK06882 3 KLSGAEMVVQSLRDE-------------GVEYVFGYpgGSVLDIYDAI-HTLGGIEHVLVRHEQAAVHMADGYARSTGKV 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 83 QIIACTSsvGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQphdLSIStndafRAVSKYWDRVLRPEQL 162
Cdd:PRK06882 69 GCVLVTS--GPGATNAITGIATAYTDSVPLVILSGQVPSNLIGTDAFQECDM---LGIS-----RPVVKHSFIVKNAEDI 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 163 MSACINAMRVLTDpAETGAVTIALPQDVQAEAYDFPVSFlQKRVHRIERTPPTQE---MLADAVKLITSKKKPLIICGGG 239
Cdd:PRK06882 139 PSTIKKAFYIAST-GRPGPVVIDIPKDMVNPANKFTYEY-PEEVSLRSYNPTVQGhkgQIKKALKALLVAKKPVLFVGGG 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 240 VRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIF-Q 318
Cdd:PRK06882 217 VITAECSEQLTQFAQKLNLPVTSSLMGLGAYPSTDKQFLGMLGMHGTYEANNAMHESDLILGIGVRFDDRTTNNLAKYcP 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 319 NPDVAFLNINIARFDAYKLDGVQVTADAKQSINALIDKLPPgyktqwgDAIKQAKADFADELQRLRQVKftdgfvpeind 398
Cdd:PRK06882 297 NAKVIHIDIDPTSISKNVPAYIPIVGSAKNVLEEFLSLLEE-------ENLAKSQTDLTAWWQQINEWK----------- 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 399 nldhdAVYAEFIKLTNSCLTQSQVLGIVNETIDNSAVI---VG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCMGY 470
Cdd:PRK06882 359 -----AKKCLEFDRTSDVIKPQQVVEAIYRLTNGDAYVasdVGqhqmfAALHYPFDKPRRWINSG--------GAGTMGF 425
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 471 EVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFRNPetn 550
Cdd:PRK06882 426 GLPAAIGVKFAHPEATVVCVTGDGSIQMNIQELSTAKQYDIPVVIVSLNNRFLGMVKQWQDLIYSGRHSQVYMNSLP--- 502
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 2006413104 551 qlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADA---KQQTVstLIDIKV 601
Cdd:PRK06882 503 ---------DFAKLAEAYGHVGIQIDTPDELEEKLTQAfsiKDKLV--FVDVNV 545
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
33-618 |
4.96e-36 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 142.98 E-value: 4.96e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGH--GNVLGIGQALeQDPGSLRLYQgRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNRI 110
Cdd:PRK07710 30 GVEVIFGYpgGAVLPLYDAL-YDCGIPHILT-RHEQGAIHAAEGYARISGKPGVVIATS--GPGATNVVTGLADAMIDSL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 111 PLLLLPGDVfASrqpdpvlqqieqphdlSISTNDAFR---------AVSKYWDRVLRPEQLMSACINAMRVLTDpAETGA 181
Cdd:PRK07710 106 PLVVFTGQV-AT----------------SVIGSDAFQeadimgitmPVTKHNYQVRKASDLPRIIKEAFHIATT-GRPGP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 182 VTIALPQDVQAE----AYDFPVSFLQKRvhriERTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFG 257
Cdd:PRK07710 168 VLIDIPKDMVVEegefCYDVQMDLPGYQ----PNYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 258 IPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSS-KWIFQNPDVAFLNINIARFDAYK 336
Cdd:PRK07710 244 IPVVHTLLGLGGFPADHPLFLGMAGMHGTYTANMALYECDLLINIGARFDDRVTGNlAYFAKEATVAHIDIDPAEIGKNV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 337 LDGVQVTADAKQSINALID-KLPPGYKTQWGDAIKQAKADFAdelqrLRQVKFTDGFVPEINDNLDHDAVYAEFIKLTNs 415
Cdd:PRK07710 324 PTEIPIVADAKQALQVLLQqEGKKENHHEWLSLLKNWKEKYP-----LSYKRNSESIKPQKAIEMLYEITKGEAIVTTD- 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 416 cLTQSQVLgivnetidnsavivgAAGSLPGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQPEREVYALVGDGA 495
Cdd:PRK07710 398 -VGQHQMW---------------AAQYYPFKTPDKWVTSG--------GLGTMGFGLPAAIGAQLAKPDETVVAIVGDGG 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 496 FLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQvgngmgsygTEFRfrnpeTNQLNGSLIPV--DFAMCAAAYGCKTY 573
Cdd:PRK07710 454 FQMTLQELSVIKELSLPVKVVILNNEALGMVRQWQ---------EEFY-----NQRYSHSLLSCqpDFVKLAEAYGIKGV 519
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 2006413104 574 KVTTEDELRKALADAKQQTVSTLIDIKVLPK-----TMAHGYGCWWHVGV 618
Cdd:PRK07710 520 RIDDELEAKEQLQHAIELQEPVVIDCRVLQSekvmpMVAPGKGLHEMVGV 569
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
32-586 |
7.26e-36 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 142.33 E-value: 7.26e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 32 HGIAAIFGH--GNVLGIGQALEQdpGSLRLYQGRNEQGMAHLAIGFAKQhkRQQIIACTSSVGPGAANMVTAAATATSNR 109
Cdd:PRK08978 14 QGVDTVFGYpgGAIMPVYDALYD--GGVEHLLCRHEQGAAMAAIGYARA--TGKVGVCIATSGPGATNLITGLADALLDS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 110 IPLLLLPGdvfasrqpdpvlqQIEQPHdlsISTnDAFR---------AVSKYWDRVLRPEQLMSACINAMRVltdpAET- 179
Cdd:PRK08978 90 VPVVAITG-------------QVSSPL---IGT-DAFQeidvlglslACTKHSFLVQSLEELPEIMAEAFEI----ASSg 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 180 --GAVTIALPQDVQAEAYDFPVSFLqkrvHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFG 257
Cdd:PRK08978 149 rpGPVLVDIPKDIQLAEGELEPHLT----TVENEPAFPAAELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATG 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 258 IPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIF-QNPDVAFLNINIARFDAYK 336
Cdd:PRK08978 225 MPAVATLKGLGAVEADHPYYLGMLGMHGTKAANLAVQECDLLIAVGARFDDRVTGKLNTFaPHAKVIHLDIDPAEINKLR 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 337 LDGVQVTADAKQSINALIDKLPPgykTQWGDAIKQAKADFAdelqrlrqvkftdgfvpeinDNLDH--DAVYAE-FIKlt 413
Cdd:PRK08978 305 QAHVALQGDLNALLPALQQPLNI---DAWRQHCAQLRAEHA--------------------WRYDHpgEAIYAPaLLK-- 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 414 nsclTQSQVLGivnetiDNSAVI--VG-----AAgslpgdlQRTWLSKSEDsyHL-EYGYSCMGYEVNAAVGVKIAQPER 485
Cdd:PRK08978 360 ----QLSDRKP------ADTVVTtdVGqhqmwVA-------QHMRFTRPEN--FItSSGLGTMGFGLPAAIGAQVARPDD 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 486 EVYALVGDGAFLMSHSELVTsIQEGK-KINVVLFDNMANGCINNLQvgngmgsygtEFRF--RNPETNqLNGSliPvDFA 562
Cdd:PRK08978 421 TVICVSGDGSFMMNVQELGT-IKRKQlPVKIVLLDNQRLGMVRQWQ----------QLFFdeRYSETD-LSDN--P-DFV 485
|
570 580
....*....|....*....|....
gi 2006413104 563 MCAAAYGCKTYKVTTEDELRKALA 586
Cdd:PRK08978 486 MLASAFGIPGQTITRKDQVEAALD 509
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
182-604 |
1.66e-34 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 137.98 E-value: 1.66e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 182 VTIALPQDVqaeaYDFPVSflqKRVHRIERTPPT------QEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEK 255
Cdd:COG3961 163 VYIELPRDV----ADAPIE---PPEAPLPLPPPAsdpaalAAAVAAAAERLAKAKRPVILAGVEVHRFGLQEELLALAEK 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 256 FGIPFAETQAGKSAIVSSHELNVGG-VGETGCLAANRLAKEADLIIGIGTRYTDFTTsskWIF-QNPDVAFLnINI---- 329
Cdd:COG3961 236 TGIPVATTLLGKSVLDESHPQFIGTyAGAASSPEVREYVENADCVLCLGVVFTDTNT---GGFtAQLDPERT-IDIqpds 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 330 ARFDAYKLDGVQVtadaKQSINALIDKLPPgYKTQWGDAIKQAKADFADELQRLRQvkftDGFVPEINDNLDH-DAVYAE 408
Cdd:COG3961 312 VRVGGHIYPGVSL----ADFLEALAELLKK-RSAPLPAPAPPPPPPPAAPDAPLTQ----DRLWQRLQAFLDPgDIVVAD 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 409 fiklTNSCLtqsqvLGIVNETI-DNSAVIVGAAgslpgdlqrtWLSksedsyhleygyscMGYEVNAAVGVKIAQPEREV 487
Cdd:COG3961 383 ----TGTSL-----FGAADLRLpEGATFIAQPL----------WGS--------------IGYTLPAALGAALAAPDRRV 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 488 YALVGDGAFLMSHSELVTSIQEGkkINVVLFdnmangCINNlqvgngmGSYGTEFRFRNPET--NQLNgsliPVDFAMCA 565
Cdd:COG3961 430 ILLVGDGAFQLTAQELSTMLRYG--LKPIIF------VLNN-------DGYTIERAIHGPDGpyNDIA----NWDYAKLP 490
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 2006413104 566 AAYGCK---TYKVTTEDELRKALADAKQQTVS-TLIDIkVLPK 604
Cdd:COG3961 491 EAFGGGnalGFRVTTEGELEEALAAAEANTDRlTLIEV-VLDK 532
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
5-591 |
4.41e-34 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 137.42 E-value: 4.41e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLdnqyiEIDGKEIKF-VHGiAAIfghgnvLGIGQALEQDpGSLRLYQGRNEQGMAHLAIGFAKQhKRQQ 83
Cdd:PRK11269 3 KMRAVDAAVLVL-----EKEGVTTAFgVPG-AAI------NPFYSAMRKH-GGIRHILARHVEGASHMAEGYTRA-TAGN 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 84 IIACTSSVGPGAANMVTAAATATSNRIPLLLLPGdvfasRQPDPVLQQIE-QPHDL-SIStndafRAVSKYWDRVLRPEQ 161
Cdd:PRK11269 69 IGVCIGTSGPAGTDMITGLYSASADSIPILCITG-----QAPRARLHKEDfQAVDIeSIA-----KPVTKWAVTVREPAL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 162 LMSACINAMRVLTDpAETGAVTIALPQDVQAEAYDF------PVSFLQKRVHR--IERTpptQEMLADAvklitskKKPL 233
Cdd:PRK11269 139 VPRVFQQAFHLMRS-GRPGPVLIDLPFDVQVAEIEFdpdtyePLPVYKPAATRaqIEKA---LEMLNAA-------ERPL 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 234 IICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVG-ETGCLAANRLAKEADLIIGIGTRYTDFTTS 312
Cdd:PRK11269 208 IVAGGGVINADASDLLVEFAELTGVPVIPTLMGWGAIPDDHPLMAGMVGlQTSHRYGNATLLASDFVLGIGNRWANRHTG 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 313 SKWIFQNpDVAFLNINI-----ARFDAYKLDgvqVTADAKQSINALID---------KLPPgyKTQWGDAIKQAKADFad 378
Cdd:PRK11269 288 SVEVYTK-GRKFVHVDIeptqiGRVFGPDLG---IVSDAKAALELLVEvarewkaagRLPD--RSAWVADCQERKRTL-- 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 379 elqrLRQVKFTDgfVP--------EINDNLDHDAVYAEFIKLtnSCLTQSQVLGIVNetiDNSAVIVGAAGSLpgdlqrt 450
Cdd:PRK11269 360 ----LRKTHFDN--VPikpqrvyeEMNKAFGRDTCYVSTIGL--SQIAAAQFLHVYK---PRHWINCGQAGPL------- 421
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 451 wlsksedsyhleygyscmGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQ 530
Cdd:PRK11269 422 ------------------GWTIPAALGVRAADPDRNVVALSGDYDFQFLIEELAVGAQFNLPYIHVLVNNAYLGLIRQAQ 483
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2006413104 531 VGNGMgSYGTEFRFRNPETNQLNGSliPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQ 591
Cdd:PRK11269 484 RAFDM-DYCVQLAFENINSPELNGY--GVDHVKVAEGLGCKAIRVFKPEDIAPALEQAKAL 541
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
33-585 |
2.02e-33 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 135.25 E-value: 2.02e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGH--GNVLGIGQALEQDPgSLRLYQGRNEQGMAHLAIGFAKQHKRQQIiaCTSSVGPGAANMVTAAATATSNRI 110
Cdd:PLN02470 27 GVDTVFAYpgGASMEIHQALTRSN-CIRNVLCRHEQGEVFAAEGYAKASGKVGV--CIATSGPGATNLVTGLADALLDSV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 111 PLLLLPGDVfasrqPDPVlqqieqphdlsISTnDAF---------RAVSKYWDRVLRPEQLMSACINAMrVLTDPAETGA 181
Cdd:PLN02470 104 PLVAITGQV-----PRRM-----------IGT-DAFqetpivevtRSITKHNYLVMDVEDIPRVIREAF-FLASSGRPGP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 182 VTIALPQDVQAEA----YDFPVSfLQKRVHRIERtPPTQEMLADAVKLITSKKKPLIICGGGVrySQACRSLQHFAEKFG 257
Cdd:PLN02470 166 VLVDIPKDIQQQLavpnWNQPMK-LPGYLSRLPK-PPEKSQLEQIVRLISESKRPVVYVGGGC--LNSSEELREFVELTG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 258 IPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIF-QNPDVAFLNINIARFDAYK 336
Cdd:PLN02470 242 IPVASTLMGLGAFPASDELSLQMLGMHGTVYANYAVDSADLLLAFGVRFDDRVTGKLEAFaSRASIVHIDIDPAEIGKNK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 337 LDGVQVTADAK---QSINALIDKLPPGYK--TQWGDAIKQAKADFAdelqrLRQVKFTDGFVPEindnldhdavYAefik 411
Cdd:PLN02470 322 QPHVSVCADVKlalQGLNKLLEERKAKRPdfSAWRAELDEQKEKFP-----LSYPTFGDAIPPQ----------YA---- 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 412 ltnscltqSQVLGivnETIDNSAVI---VG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQP 483
Cdd:PLN02470 383 --------IQVLD---ELTDGNAIIstgVGqhqmwAAQWYKYKEPRRWLTSG--------GLGAMGFGLPAAIGAAAANP 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 484 EREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCI----NNLQVGNGMGSYgtefrFRNPEtnqlNGSLIPV 559
Cdd:PLN02470 444 DAIVVDIDGDGSFIMNIQELATIHVENLPVKIMVLNNQHLGMVvqweDRFYKANRAHTY-----LGDPD----AEAEIFP 514
|
570 580
....*....|....*....|....*.
gi 2006413104 560 DFAMCAAAYGCKTYKVTTEDELRKAL 585
Cdd:PLN02470 515 DFLKFAEGCKIPAARVTRKSDLREAI 540
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
5-602 |
2.60e-32 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 131.65 E-value: 2.60e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDNqyieidgkeikfvHGIAAIFG----HGnvLGIGQALEQDpGSLRLYQGRNEQGMAHLAIGFAKQhk 80
Cdd:PRK07064 2 KVTVGELIAAFLEQ-------------CGVKTAFGvisiHN--MPILDAIGRR-GKIRFVPARGEAGAVNMADAHARV-- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 81 RQQIIACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVfASRQPDPVLQQI-EQPHDLSIstndaFRAVSKYWDRVLRP 159
Cdd:PRK07064 64 SGGLGVALTSTGTGAGNAAGALVEALTAGTPLLHITGQI-ETPYLDQDLGYIhEAPDQLTM-----LRAVSKAAFRVRSA 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 160 EQLMSACINAMRV-LTDPaeTGAVTIALPQDVQAEAYDFP--VSFLQKRVHriertPPTQEMLADAVKLITSKKKPLIIC 236
Cdd:PRK07064 138 ETALATIREAVRVaLTAP--TGPVSVEIPIDIQAAEIELPddLAPVHVAVP-----EPDAAAVAELAERLAAARRPLLWL 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 237 GGGVRysQACRSLQHFAEkFGIPFAETQAGKSAIVSSHELNVGGVGETGclAANRLAKEADLIIGIGTRYTDFTTsSKWI 316
Cdd:PRK07064 211 GGGAR--HAGAEVKRLVD-LGFGVVTSTQGRGVVPEDHPASLGAFNNSA--AVEALYKTCDLLLVVGSRLRGNET-LKYS 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 317 FQNPDvaflniNIARFDA--------YKLDgVQVTADAKQSINALIDKLPPGYktqWGDaikqakADFADELQRLRQV-- 386
Cdd:PRK07064 285 LALPR------PLIRVDAdaaadgrgYPND-LFVHGDAARVLARLADRLEGRL---SVD------PAFAADLRAAREAav 348
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 387 -KFTDGFVP--EINDNLdHDAVYAEFIkltnscltqsqvlgIVNE-TIDNSavivgaagslpgdlqrTW------LSKSE 456
Cdd:PRK07064 349 aDLRKGLGPyaKLVDAL-RAALPRDGN--------------WVRDvTISNS----------------TWgnrllpIFEPR 397
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 457 DSYHLEYGYSCMGYEVnaAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNgmg 536
Cdd:PRK07064 398 ANVHALGGGIGQGLAM--AIGAALAGPGRKTVGLVGDGGLMLNLGELATAVQENANMVIVLMNDGGYGVIRNIQDAQ--- 472
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2006413104 537 sYGTEFRFrnpetNQLNGSlipvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVL 602
Cdd:PRK07064 473 -YGGRRYY-----VELHTP----DFALLAASLGLPHWRVTSADDFEAVLREALAKEGPVLVEVDML 528
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
421-601 |
3.16e-31 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 119.67 E-value: 3.16e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 421 QVLGIVNETIDNSAVIVGAAGSLPGDLQRTWLSKSEDSYHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSH 500
Cdd:cd00568 1 RVLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRPVVCIAGDGGFMMTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 501 SELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMG-SYGTEFRfrnpetnqlngsliPVDFAMCAAAYGCKTYKVTTED 579
Cdd:cd00568 81 QELATAVRYGLPVIVVVFNNGGYGTIRMHQEAFYGGrVSGTDLS--------------NPDFAALAEAYGAKGVRVEDPE 146
|
170 180
....*....|....*....|..
gi 2006413104 580 ELRKALADAKQQTVSTLIDIKV 601
Cdd:cd00568 147 DLEAALAEALAAGGPALIEVKT 168
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
32-587 |
7.70e-29 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 121.74 E-value: 7.70e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 32 HGIAAIFGH--GNVLGIGQALEQDPgSLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNR 109
Cdd:PRK09107 24 QGVEHIFGYpgGAVLPIYDEIFQQD-DIQHILVRHEQGAGHAAEGYARSTGKPGVVLVTS--GPGATNAVTPLQDALMDS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 110 IPLLLLPGDVfasrqPDPVLqqieqphdlsisTNDAF---------RAVSKYWDRVLRPEQLMSACINAMRVLTDpAETG 180
Cdd:PRK09107 101 IPLVCITGQV-----PTHLI------------GSDAFqecdtvgitRPCTKHNWLVKDVNDLARVIHEAFHVATS-GRPG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 181 AVTIALPQDVQ-AEAYDFPVSFLQKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVRYS--QACRSLQHFAEKFG 257
Cdd:PRK09107 163 PVVVDIPKDVQfATGTYTPPQKAPVHVSYQPKVKGDAEAITEAVELLANAKRPVIYSGGGVINSgpEASRLLRELVELTG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 258 IPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTD--------FTTSSKWIFQNPDVAFLNINI 329
Cdd:PRK09107 243 FPITSTLMGLGAYPASGKNWLGMLGMHGTYEANMAMHDCDVMLCVGARFDDritgrldaFSPNSKKIHIDIDPSSINKNV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 330 aRFDAYKL-DGVQVTADAKQSINALIDKLPPGYKTQWGDAIKQAKAdfadeLQRLRQVKFTDGFVPEindnldhdavYAe 408
Cdd:PRK09107 323 -RVDVPIIgDVGHVLEDMLRLWKARGKKPDKEALADWWGQIARWRA-----RNSLAYTPSDDVIMPQ----------YA- 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 409 FIKLtnSCLTQSQVLGIVNEtidnsaviVG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQP 483
Cdd:PRK09107 386 IQRL--YELTKGRDTYITTE--------VGqhqmwAAQFFGFEEPNRWMTSG--------GLGTMGYGLPAALGVQIAHP 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 484 EREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQV---GNgmgsygtefRFRNPETNQLngsliPvD 560
Cdd:PRK09107 448 DALVIDIAGDASIQMCIQEMSTAVQYNLPVKIFILNNQYMGMVRQWQQllhGN---------RLSHSYTEAM-----P-D 512
|
570 580
....*....|....*....|....*..
gi 2006413104 561 FAMCAAAYGCKTYKVTTEDELRKALAD 587
Cdd:PRK09107 513 FVKLAEAYGAVGIRCEKPGDLDDAIQE 539
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
5-601 |
1.09e-28 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 121.00 E-value: 1.09e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDNQyieidgkeikfvhGIAAIFGH--GNVLGIGQALEQDPgSLRLYQGRNEQGMAHLAIGFAKQHKRQ 82
Cdd:PRK06466 3 LLSGAEMLVRALRDE-------------GVEYIYGYpgGAVLHIYDALFKQD-KVEHILVRHEQAATHMADGYARATGKT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 83 QIIACTSsvGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQphdLSIStndafRAVSKYWDRVLRPEQL 162
Cdd:PRK06466 69 GVVLVTS--GPGATNAITGIATAYMDSIPMVVLSGQVPSTLIGEDAFQETDM---VGIS-----RPIVKHSFMVKHASEI 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 163 mSACINAMRVLTDPAETGAVTIALPQDVQAEAYDFPVSFlQKRVHRIERTPPTQE---MLADAVKLITSKKKPLIICGGG 239
Cdd:PRK06466 139 -PEIIKKAFYIAQSGRPGPVVVDIPKDMTNPAEKFEYEY-PKKVKLRSYSPAVRGhsgQIRKAVEMLLAAKRPVIYSGGG 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 240 VRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIF-Q 318
Cdd:PRK06466 217 VVLGNASALLTELAHLLNLPVTNTLMGLGGFPGTDRQFLGMLGMHGTYEANMAMHHADVILAVGARFDDRVTNGPAKFcP 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 319 NPDVAFLNINIARFDAYKLDGVQVTADAKQSINALIDKLppgyKTQWGDAIKQAKADFADELQRLRQVKftdGFVPeind 398
Cdd:PRK06466 297 NAKIIHIDIDPASISKTIKADIPIVGPVESVLTEMLAIL----KEIGEKPDKEALAAWWKQIDEWRGRH---GLFP---- 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 399 nldHDAVYAEFIKltnscltQSQVLGIVNETIDNSAVI---VG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCMGY 470
Cdd:PRK06466 366 ---YDKGDGGIIK-------PQQVVETLYEVTNGDAYVtsdVGqhqmfAAQYYKFNKPNRWINSG--------GLGTMGF 427
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 471 EVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFRNPetn 550
Cdd:PRK06466 428 GLPAAMGVKLAFPDQDVACVTGEGSIQMNIQELSTCLQYGLPVKIINLNNGALGMVRQWQDMQYEGRHSHSYMESLP--- 504
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 2006413104 551 qlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADA---KQQTVstLIDIKV 601
Cdd:PRK06466 505 ---------DFVKLAEAYGHVGIRITDLKDLKPKLEEAfamKDRLV--FIDIYV 547
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
33-603 |
1.22e-26 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 114.70 E-value: 1.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGhgnVLGIGQA----LEQDPGsLRLYQGRNEQ--GMAHLAIGFAKQhkrQQIIACTSSvGPGAANMVTAAATAT 106
Cdd:PRK09259 24 GIDTIYG---VVGIPITdlarLAQAEG-IRYIGFRHEQsaGNAAAAAGFLTQ---KPGVCLTVS-APGFLNGLTALANAT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 107 SNRIPLLLLPGdvfASRQPDPVLQQ--IEQPHDLSIStndafRAVSKYWDRVLRPEQLMSACINAMRVLTDpAETGAVTI 184
Cdd:PRK09259 96 TNCFPMIMISG---SSEREIVDLQQgdYEELDQLNAA-----KPFCKAAFRVNRAEDIGIGVARAIRTAVS-GRPGGVYL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 185 ALPQDVQAEAYDFPVS--FLQKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAE 262
Cdd:PRK09259 167 DLPAKVLAQTMDADEAltSLVKVVDPAPAQLPAPEAVDRALDLLKKAKRPLIILGKGAAYAQADEQIREFVEKTGIPFLP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 263 TQAGKSAIVSSHELNVGgvgetgclAANRLA-KEADLIIGIGTRYT---DFTTSSKWifqNPDVAFLNINIA--RFDAYK 336
Cdd:PRK09259 247 MSMAKGLLPDTHPQSAA--------AARSLAlANADVVLLVGARLNwllSHGKGKTW---GADKKFIQIDIEpqEIDSNR 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 337 LDGVQVTADAKQSINALIDKL---PPGYKTQWGDAIKQAKA-DFADELQRLRQVKFTDGFvpeindnldHDAVYAefikl 412
Cdd:PRK09259 316 PIAAPVVGDIGSVMQALLAGLkqnTFKAPAEWLDALAERKEkNAAKMAEKLSTDTQPMNF---------YNALGA----- 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 413 TNSCLTQSQVLGIVNEtidnsavivgAAGSLpgDLQRTWLSKSEDSYHLEYGY-----SCMGYEVNAAVgvkiaQPEREV 487
Cdd:PRK09259 382 IRDVLKENPDIYLVNE----------GANTL--DLARNIIDMYKPRHRLDCGTwgvmgIGMGYAIAAAV-----ETGKPV 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 488 YALVGDGAFLMSHSELVTSIQEGKKINVVLFDNmangcinnlqvgNGMgsygtefrFRNPETNQLNGS-LIPVDFA---- 562
Cdd:PRK09259 445 VAIEGDSAFGFSGMEVETICRYNLPVTVVIFNN------------GGI--------YRGDDVNLSGAGdPSPTVLVhhar 504
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 2006413104 563 --MCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLP 603
Cdd:PRK09259 505 ydKMMEAFGGVGYNVTTPDELRHALTEAIASGKPTLINVVIDP 547
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
10-188 |
1.61e-26 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 105.69 E-value: 1.61e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 10 QALVKFLDNQYIEIdgkeikfvhgIAAIFGHGNvLGIGQALEQDpgSLRLYQGRNEQGMAHLAIGFAKQHKRqqIIACTS 89
Cdd:cd07035 1 DALVEALKAEGVDH----------VFGVPGGAI-LPLLDALARS--GIRYILVRHEQGAVGMADGYARATGK--PGVVLV 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 90 SVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQPhdlsistnDAFRAVSKYWDRVLRPEQLMSACINA 169
Cdd:cd07035 66 TSGPGLTNAVTGLANAYLDSIPLLVITGQRPTAGEGRGAFQEIDQV--------ALFRPITKWAYRVTSPEEIPEALRRA 137
|
170
....*....|....*....
gi 2006413104 170 MRVLTDPAeTGAVTIALPQ 188
Cdd:cd07035 138 FRIALSGR-PGPVALDLPK 155
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
61-603 |
3.32e-26 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 113.00 E-value: 3.32e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 61 QGRNEQGMAHLAIGFAKQHKRqqIIACTSSVGPGAANMVTAAATATSNRIPLLLLPGdvfasrqpdpvlqQIEQP---HD 137
Cdd:PRK06457 44 QVRHEEGAALAASVEAKITGK--PSACMGTSGPGSIHLLNGLYDAKMDHAPVIALTG-------------QVESDmigHD 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 138 LSISTN--DAFRAVSKYWDRVLRPEQ----LMSACINAMrvltdpAETGAVTIALPQDVQAEAYDFPVSFlqkrvHRIER 211
Cdd:PRK06457 109 YFQEVNltKLFDDVAVFNQILINPENaeyiIRRAIREAI------SKRGVAHINLPVDILRKSSEYKGSK-----NTEVG 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 212 TPPTQEMLADAVKLITSKKKPLIICGGGVRysQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANR 291
Cdd:PRK06457 178 KVKYSIDFSRAKELIKESEKPVLLIGGGTR--GLGKEINRFAEKIGAPIIYTLNGKGILPDLDPKVMGGIGLLGTKPSIE 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 292 LAKEADLIIGIGTRYtdfttsskwifqnPDVAFLNINIarfdayklDGVQVTADAkQSINALIDKLPPgYKTQWGDAIkQ 371
Cdd:PRK06457 256 AMDKADLLIMLGTSF-------------PYVNFLNKSA--------KVIQVDIDN-SNIGKRLDVDLS-YPIPVAEFL-N 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 372 AKADFADElqrlrqvKFTDGFVPEINDNLDhDAVYAEFIklTNSCLTQSQVLGIVNETIDNSAVIVGAAGSLPGDLQRTW 451
Cdd:PRK06457 312 IDIEEKSD-------KFYEELKGKKEDWLD-SISKQENS--LDKPMKPQRVAYIVSQKCKKDAVIVTDTGNVTMWTARHF 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 452 LSKSEDSYHLEYGYSCMGYEVNAAVGVKIA-QPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQ 530
Cdd:PRK06457 382 RASGEQTFIFSAWLGSMGIGVPGSVGASFAvENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNSKLGMIKFEQ 461
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2006413104 531 VGNGMGSYGTEfrFRNPetnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVLP 603
Cdd:PRK06457 462 EVMGYPEWGVD--LYNP------------DFTKIAESIGFKGFRLEEPKEAEEIIEEFLNTKGPAVLDAIVDP 520
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
22-603 |
1.26e-25 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 111.82 E-value: 1.26e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 22 EIDGKEIkFVHGIAA-----IFGH--GNVLGIGQAL-EQDpgSLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGP 93
Cdd:PRK06965 20 DSIGAEI-LMKALAAegvefIWGYpgGAVLYIYDELyKQD--KIQHVLVRHEQAAVHAADGYARATGKVGVALVTS--GP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 94 GAANMVTAAATATSNRIPLLLLPGDVfasrqPDPVLQQieqphdlsistnDAF---------RAVSKYWDRVLRPEQLMS 164
Cdd:PRK06965 95 GVTNAVTGIATAYMDSIPMVVISGQV-----PTAAIGQ------------DAFqecdtvgitRPIVKHNFLVKDVRDLAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 165 ACINAMRVltdpAETG---AVTIALPQDV--QAEAYDFPVSFLQKRVHRIERTPPTQemLADAVKLITSKKKPLIICGGG 239
Cdd:PRK06965 158 TVKKAFYI----ARTGrpgPVVVDIPKDVskTPCEYEYPKSVEMRSYNPVTKGHSGQ--IRKAVSLLLSAKRPYIYTGGG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 240 VRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTRYTDFTTSSKWIFQN 319
Cdd:PRK06965 232 VILANASRELRQLADLLGYPVTNTLMGLGAYPASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRVIGNPAHFAS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 320 PDVAFLNINI---ARFDAYKLDgVQVTADAKQSINALIDKLPPGykTQWGDAikQAKADFADELQRLRQVkftdgfvpei 396
Cdd:PRK06965 312 RPRKIIHIDIdpsSISKRVKVD-IPIVGDVKEVLKELIEQLQTA--EHGPDA--DALAQWWKQIEGWRSR---------- 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 397 nDNLDHDAVyAEFIKltnsclTQSQVLGIVNETiDNSAVI---VG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCM 468
Cdd:PRK06965 377 -DCLKYDRE-SEIIK------PQYVVEKLWELT-DGDAFVcsdVGqhqmwAAQFYRFNEPRRWINSG--------GLGTM 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 469 GYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFRNPe 548
Cdd:PRK06965 440 GVGLPYAMGIKMAHPDDDVVCITGEGSIQMCIQELSTCLQYDTPVKIISLNNRYLGMVRQWQEIEYSKRYSHSYMDALP- 518
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 2006413104 549 tnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADA---KQQTVstLIDIKVLP 603
Cdd:PRK06965 519 -----------DFVKLAEAYGHVGMRIEKTSDVEPALREAlrlKDRTV--FLDFQTDP 563
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
9-601 |
1.41e-25 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 111.10 E-value: 1.41e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 9 AQALVKFLDNQyieidgkEIKFVHGI--AAI---FghgnvlgigQALEQDpgSLRLYQGRNEQGMAHLAIGFAKQHKRQQ 83
Cdd:PRK08617 8 ADLVVDSLINQ-------GVKYVFGIpgAKIdrvF---------DALEDS--GPELIVTRHEQNAAFMAAAIGRLTGKPG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 84 IIACTSsvGPGAANMVTAAATATSNRIPLLLLPGDVfasRQPDpVLQQIEQphdlSISTNDAFRAVSKYWDRVLRPEQLM 163
Cdd:PRK08617 70 VVLVTS--GPGVSNLATGLVTATAEGDPVVAIGGQV---KRAD-RLKRTHQ----SMDNVALFRPITKYSAEVQDPDNLS 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 164 SACINAMRVltdpAET---GAVTIALPQDV-QAEAYDFPVSFLQKrvhrIERTPPTQEMLADAVKLITSKKKPLIICGGG 239
Cdd:PRK08617 140 EVLANAFRA----AESgrpGAAFVSLPQDVvDAPVTSKAIAPLSK----PKLGPASPEDINYLAELIKNAKLPVLLLGMR 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 240 VRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELN-VGGVGetgcLAAN----RLAKEADLIIGIG---TRYtdftT 311
Cdd:PRK08617 212 ASSPEVTAAIRRLLERTNLPVVETFQAAGVISRELEDHfFGRVG----LFRNqpgdELLKKADLVITIGydpIEY----E 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 312 SSKWIFQNpDVAFLNINI--ARFDAYKLDGVQVTADAKQSINALIDKLPpgyktqwGDAIKQAKADFADELQRLRQVkfT 389
Cdd:PRK08617 284 PRNWNSEG-DATIIHIDVlpAEIDNYYQPERELIGDIAATLDLLAEKLD-------GLSLSPQSLEILEELRAQLEE--L 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 390 DGFVPEINDNLDHDavyAEFIKltnscltqsqvlgIVNETIDNSAVIVGAAGSLpgdlqRTWLSKSEDSY---HLEY--G 464
Cdd:PRK08617 354 AERPARLEEGAVHP---LRIIR-------------ALQDIVTDDTTVTVDVGSH-----YIWMARYFRSYeprHLLFsnG 412
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 465 YSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQegKKINVVLF---DNMANgcINNLQVGNGMG-SYGT 540
Cdd:PRK08617 413 MQTLGVALPWAIAAALVRPGKKVVSVSGDGGFLFSAMELETAVR--LKLNIVHIiwnDGHYN--MVEFQEEMKYGrSSGV 488
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2006413104 541 EFrfrnpetnqlnGsliPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:PRK08617 489 DF-----------G---PVDFVKYAESFGAKGLRVTSPDELEPVLREALATDGPVVIDIPV 535
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
56-504 |
8.60e-24 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 105.57 E-value: 8.60e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 56 SLRLYQGRNEQGMAHLAIGFAKQHKRQQIIACTSsvGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQP 135
Cdd:PRK05858 42 GIRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTA--GPGVTNGMSAMAAAQFNQSPLVVLGGRAPALRWGMGSLQEIDHV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 136 hdlsistnDAFRAVSKYWDRVLRPEQLMSACINAMRVLTDPaETGAVTIALPQDV---QAEAYDFPVSFLQKrvhRIERT 212
Cdd:PRK05858 120 --------PFVAPVTKFAATAQSAENAGRLVDQALQAAVTP-HRGPVFVDFPMDHafsMADDDGRPGALTEL---PAGPT 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 213 PPTQEmLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGgvgetgclAANRL 292
Cdd:PRK05858 188 PDPDA-LARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGRGVVPADHPLAFS--------RARGK 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 293 A-KEADLIIGIGTRyTDFTTSSKWIFQNPDVaflnINIARFDAYKLDGVQVTADAKQSINALIDklppGYKTQWGDaikq 371
Cdd:PRK05858 259 AlGEADVVLVVGVP-MDFRLGFGVFGGTAQL----VHVDDAPPQRAHHRPVAAGLYGDLSAILS----ALAGAGGD---- 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 372 aKADFADELQRLRQVKFT--DGFVPEINDNLD--HDA-VYAEFIKLtnscltqsqvlgivnetIDNSAVIVGAAGS---- 442
Cdd:PRK05858 326 -RTDHQGWIEELRTAETAarARDAAELADDRDpiHPMrVYGELAPL-----------------LDRDAIVIGDGGDfvsy 387
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2006413104 443 --------LPGdlqrTWLSKSEdsyhleygYSCMGYEVNAAVGVKIAQPEREVYALVGDGAF---LMSHSELV 504
Cdd:PRK05858 388 agryidpyRPG----CWLDPGP--------FGCLGTGPGYALAARLARPSRQVVLLQGDGAFgfsLMDVDTLV 448
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
8-193 |
1.64e-23 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 97.69 E-value: 1.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 8 VAQALVKFLDNqyieidgkeikfvHGIAAIFGH--GNVLGIGQALEQDPGsLRLYQGRNEQGMAHLAIGFAKQHKRQQII 85
Cdd:pfam02776 1 GAEALADVLKA-------------LGVDTVFGVpgGHILPLLDALAKSPG-IRYVLTRHEQGAAFAADGYARATGKPGVV 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 86 ACTSsvGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIeqphdlsISTNDAFRAVSKYWDRVLRPEQLMSA 165
Cdd:pfam02776 67 LVTS--GPGATNALTGLANAYVDSVPLLVISGQRPRSLVGRGALQQE-------LDQLALFRPVTKWAVRVTSADEIPEV 137
|
170 180
....*....|....*....|....*...
gi 2006413104 166 CINAMRVLTDPaETGAVTIALPQDVQAE 193
Cdd:pfam02776 138 LRRAFRAALSG-RPGPVYLEIPLDVLLE 164
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
421-603 |
2.64e-22 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 94.52 E-value: 2.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 421 QVLGIVNETIDNSAVIVGAAGS--------LPGDLQRTWlsksedsyHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVG 492
Cdd:cd02014 6 RVAAELNKRAPDDAIFTIDVGNvtvwaarhLRMNGKQRF--------ILSGLLATMGNGLPGAIAAKLAYPDRQVIALSG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 493 DGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEfrfrnpetnqlngsLIPVDFAMCAAAYGCKT 572
Cdd:cd02014 78 DGGFAMLMGDLITAVKYNLPVIVVVFNNSDLGFIKWEQEVMGQPEFGVD--------------LPNPDFAKIAEAMGIKG 143
|
170 180 190
....*....|....*....|....*....|.
gi 2006413104 573 YKVTTEDELRKALADAKQQTVSTLIDIKVLP 603
Cdd:cd02014 144 IRVEDPDELEAALDEALAADGPVVIDVVTDP 174
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
421-601 |
9.48e-21 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 89.90 E-value: 9.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 421 QVLGIVNETIDNSAVIVGAAGS--------LPGDLQRTWLSKsedsyhleYGYSCMGYEVNAAVGVKIAQPEREVYALVG 492
Cdd:cd02004 3 RVLHELQEALPDDAIIVSDGGNtmdwaryiLRPRKPRHRLDA--------GTFGTLGVGLGYAIAAALARPDKRVVLVEG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 493 DGAFLMSHSELVTSIQEGKKINVVLfdnMANGCInnlqvgnGMGSYGTEFRFrnpeTNQLNGS--LIPVDFAMCAAAYGC 570
Cdd:cd02004 75 DGAFGFSGMELETAVRYNLPIVVVV---GNNGGW-------YQGLDGQQLSY----GLGLPVTtlLPDTRYDLVAEAFGG 140
|
170 180 190
....*....|....*....|....*....|.
gi 2006413104 571 KTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:cd02004 141 KGELVTTPEELKPALKRALASGKPALINVII 171
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
421-606 |
1.37e-20 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 89.86 E-value: 1.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 421 QVLGIVNETIDNSAVI---VG-----AAGSLPGDLQRTWLSKSedsyhleyGYSCMGYEVNAAVGVKIAQPEREVYALVG 492
Cdd:cd02015 5 EVIKELSELTPGDAIVttdVGqhqmwAAQYYRFKKPRSWLTSG--------GLGTMGFGLPAAIGAKVARPDKTVICIDG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 493 DGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEFRFRNPetnqlngslipvDFAMCAAAYGCKT 572
Cdd:cd02015 77 DGSFQMNIQELATAAQYNLPVKIVILNNGSLGMVRQWQELFYEGRYSHTTLDSNP------------DFVKLAEAYGIKG 144
|
170 180 190
....*....|....*....|....*....|....
gi 2006413104 573 YKVTTEDELRKALADAKQQTVSTLIDIKVLPKTM 606
Cdd:cd02015 145 LRVEKPEELEAALKEALASDGPVLLDVLVDPEEN 178
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
86-599 |
1.65e-19 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 92.36 E-value: 1.65e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 86 ACTSSVGPGAANMVTAAATATSNRIPLLLLpgdvfASRQPDpvlQQI-----EQPHDLSIstndaFRAVSKYWDRVLRPE 160
Cdd:PRK06546 69 VCAGSCGPGNLHLINGLYDAHRSGAPVLAI-----ASHIPS---AQIgsgffQETHPDRL-----FVECSGYCEMVSSAE 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 161 Q----LMSACINAMrvltdpAETGAVTIALPQDV--QAEAYDFPVSFLQKRVHRIErtpPTQEMLADAVKLITSKKKPLI 234
Cdd:PRK06546 136 QaprvLHSAIQHAV------AGGGVSVVTLPGDIadEPAPEGFAPSVISPRRPTVV---PDPAEVRALADAINEAKKVTL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 235 ICGGGVRYSQAcrSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTR--YTDFTts 312
Cdd:PRK06546 207 FAGAGVRGAHA--EVLALAEKIKAPVGHSLRGKEWIQYDNPFDVGMSGLLGYGAAHEAMHEADLLILLGTDfpYDQFL-- 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 313 skwifqnPDVAFLNINIarfDAYKLD-----GVQVTADAKQSINALIDKLPPgyktqwgdaikqaKAD--FADELQRlRQ 385
Cdd:PRK06546 283 -------PDVRTAQVDI---DPEHLGrrtrvDLAVHGDVAETIRALLPLVKE-------------KTDrrFLDRMLK-KH 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 386 VKFTDGFVPEINDNLD-HDAVYAEFikltnscltqsqVLGIVNETIDNSAVI--------VGAAGSLPGDLQRTWLSkse 456
Cdd:PRK06546 339 ARKLEKVVGAYTRKVEkHTPIHPEY------------VASILDELAADDAVFtvdtgmcnVWAARYITPNGRRRVIG--- 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 457 dSY-HleygyscmGYEVNA---AVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVG 532
Cdd:PRK06546 404 -SFrH--------GSMANAlphAIGAQLADPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKVVVFNNSTLGMVKLEMLV 474
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2006413104 533 NGMGSYGTEfrfrNPetnqlngsliPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDI 599
Cdd:PRK06546 475 DGLPDFGTD----HP----------PVDYAAIAAALGIHAVRVEDPKDVRGALREAFAHPGPALVDV 527
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
70-601 |
8.75e-18 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 86.98 E-value: 8.75e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 70 HLAIGFAKQHKRQQIIACtsSVGPGAANMVTAAATATSNRIPLLllpgdVFASRQPdpvlqQIEQPH----DLSIS-TND 144
Cdd:PRK08327 64 SMAHGYALVTGKPQAVMV--HVDVGTANALGGVHNAARSRIPVL-----VFAGRSP-----YTEEGElgsrNTRIHwTQE 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 145 AF------RAVSKyWDRVLR-PEQLMSACINAMRVL-TDPAetGAVTIALPQDVQAEAYDfPVSFLQKRVHRIERTPPTQ 216
Cdd:PRK08327 132 MRdqgglvREYVK-WDYEIRrGDQIGEVVARAIQIAmSEPK--GPVYLTLPREVLAEEVP-EVKADAGRQMAPAPPAPDP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 217 EMLADAVKLITSKKKPLIICGGGVRYSQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVgetgclaANRLAKEA 296
Cdd:PRK08327 208 EDIARAAEMLAAAERPVIITWRAGRTAEGFASLRRLAEELAIPVVEYAGEVVNYPSDHPLHLGPD-------PRADLAEA 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 297 DLIIGIGT------RYTDFTTSSKWIFQNPDVAFLNINIARFDAyKLDGVQVTADAKQSINALIDKLPPGyktqwGDAIK 370
Cdd:PRK08327 281 DLVLVVDSdvpwipKKIRPDADARVIQIDVDPLKSRIPLWGFPC-DLCIQADTSTALDQLEERLKSLASA-----ERRRA 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 371 QAKADFADELQRLRQVKFTDgfvpEINDNLDHDAVYAEFIkltNSCLtqsqvlgivNETIDNSAVIVGAAGSLPGDLQR- 449
Cdd:PRK08327 355 RRRRAAVRELRIRQEAAKRA----EIERLKDRGPITPAYL---SYCL---------GEVADEYDAIVTEYPFVPRQARLn 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 450 ---TWLSKSEDSYhleygyscMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQE--GKKINVVLFDnmaNG 524
Cdd:PRK08327 419 kpgSYFGDGSAGG--------LGWALGAALGAKLATPDRLVIATVGDGSFIFGVPEAAHWVAEryGLPVLVVVFN---NG 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 525 CINNLQ----------VGNGMGSY-GTEFrfrNPETnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADA----K 589
Cdd:PRK08327 488 GWLAVKeavlevypegYAARKGTFpGTDF---DPRP----------DFAKIAEAFGGYGERVEDPEELKGALRRAlaavR 554
|
570
....*....|..
gi 2006413104 590 QQTVSTLIDIKV 601
Cdd:PRK08327 555 KGRRSAVLDVIV 566
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
464-601 |
2.61e-17 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 80.02 E-value: 2.61e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 464 GYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTEfr 543
Cdd:cd02010 46 GLATMGVALPGAIGAKLVYPDRKVVAVSGDGGFMMNSQELETAVRLKIPLVVLIWNDNGYGLIKWKQEKEYGRDSGVD-- 123
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2006413104 544 FRNPetnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:cd02010 124 FGNP------------DFVKYAESFGAKGYRIESADDLLPVLERALAADGVHVIDCPV 169
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
426-601 |
3.11e-17 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 79.95 E-value: 3.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 426 VNETIDNSAVIVGAAGSLPGDLQRTWLSKSEDSYHLEYGYScMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVT 505
Cdd:cd02002 10 LAAALPEDAIIVDEAVTNGLPLRDQLPLTRPGSYFTLRGGG-LGWGLPAAVGAALANPDRKVVAIIGDGSFMYTIQALWT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 506 SIQEGKKINVVLFDnmaNGCINNLQV-GNGMGSYGTEFRFRNPetnqlNGSLIP-VDFAMCAAAYGCKTYKVTTEDELRK 583
Cdd:cd02002 89 AARYGLPVTVVILN---NRGYGALRSfLKRVGPEGPGENAPDG-----LDLLDPgIDFAAIAKAFGVEAERVETPEELDE 160
|
170
....*....|....*...
gi 2006413104 584 ALADAKQQTVSTLIDIKV 601
Cdd:cd02002 161 ALREALAEGGPALIEVVV 178
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
465-604 |
5.57e-16 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 76.42 E-value: 5.57e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 465 YSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGkkINVVLFdnmangCINNlqvgngmGSYGTEfRF 544
Cdd:cd02005 49 WGSIGYSVPAALGAALAAPDRRVILLVGDGSFQMTVQELSTMIRYG--LNPIIF------LINN-------DGYTIE-RA 112
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2006413104 545 RNPETNQLNgSLIPVDFAMCAAAYGC----KTYKVTTEDELRKALADAKQQT-VSTLIDIkVLPK 604
Cdd:cd02005 113 IHGPEASYN-DIANWNYTKLPEVFGGggggLSFRVKTEGELDEALKDALFNRdKLSLIEV-ILPK 175
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
5-588 |
1.61e-14 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 76.57 E-value: 1.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 5 KLTVAQALVKFLDNQyieidgkeikfvhGIAAIFG-HGNVL-GIGQALEQDpGSLRLYQGRNEQGMAhLAIGfAKQHKRQ 82
Cdd:PRK09124 2 KQTVADYIAKTLEQA-------------GVKRIWGvTGDSLnGLSDSLRRM-GTIEWMHTRHEEVAA-FAAG-AEAQLTG 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 83 QIIACTSSVGPGAANMVTAAATATSNRIPLLLLpgdvfASRQPDPVLQ----QIEQPHDLsistndaFRAVSKYWDRVLR 158
Cdd:PRK09124 66 ELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAI-----AAHIPSSEIGsgyfQETHPQEL-------FRECSHYCELVSN 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 159 PEQLMSACINAMRVLTDpaETGAVTIALPQDV--QAEAYDFPVSFLQKRVHRIerTPPTQEmLADAVKLITSKKKPLIIC 236
Cdd:PRK09124 134 PEQLPRVLAIAMRKAIL--NRGVAVVVLPGDValKPAPERATPHWYHAPQPVV--TPAEEE-LRKLAALLNGSSNITLLC 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 237 GGGVrySQACRSLQHFAEKFGIPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEADLIIGIGTrytDFttsskwi 316
Cdd:PRK09124 209 GSGC--AGAHDELVALAETLKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGYHAMMNCDTLLMLGT---DF------- 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 317 fqnPDVAFL--NINIARFDA--------YKLDgVQVTADAKQSINALIDKLPPGYKTQWGDAIKQAKADFADELQRLRQV 386
Cdd:PRK09124 277 ---PYRQFYptDAKIIQIDInpgslgrrSPVD-LGLVGDVKATLAALLPLLEEKTDRKFLDKALEHYRKARKGLDDLAVP 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 387 kfTDGFVP--------EINDNLDHDAVYaefikltnscltqsqvlgivneTIDNSAVIVGAAGSLPGDLQRTWLSkseds 458
Cdd:PRK09124 353 --SDGGKPihpqylarQISEFAADDAIF----------------------TCDVGTPTVWAARYLKMNGKRRLLG----- 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 459 yhlEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSY 538
Cdd:PRK09124 404 ---SFNHGSMANAMPQALGAQAAHPGRQVVALSGDGGFSMLMGDFLSLVQLKLPVKIVVFNNSVLGFVAMEMKAGGYLTD 480
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 2006413104 539 GTEfrFRNPetnqlngslipvDFAMCAAAYGCKTYKVTTEDELRKALADA 588
Cdd:PRK09124 481 GTD--LHNP------------DFAAIAEACGITGIRVEKASELDGALQRA 516
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
33-505 |
4.46e-14 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 75.33 E-value: 4.46e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 33 GIAAIFGhgnvlgigqALEQDPGSLRLYQGRNEQGMAHLAIGFAKQhkRQQIIACTSSVGPGAANMVTAAATATSNRIPL 112
Cdd:PRK08273 28 GINGLLG---------ALGRADDKPEFVQARHEEMAAFMAVAHAKF--TGEVGVCLATSGPGAIHLLNGLYDAKLDHVPV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 113 LLLPGdvfasrqpdpvlQQ--------IEQPHDLSistnDAFRAV-SKYWDRVLRPEQLMSACINAMRVLTdpAETGAVT 183
Cdd:PRK08273 97 VAIVG------------QQaraalgghYQQEVDLQ----SLFKDVaGAFVQMVTVPEQLRHLVDRAVRTAL--AERTVTA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 184 IALPQDVQAEAY-DFPVSFlqKRVH-----RIERTPPTQEMLADAVKLITSKKKPLIICGGGVRysQACRSLQHFAEKFG 257
Cdd:PRK08273 159 VILPNDVQELEYePPPHAH--GTVHsgvgyTRPRVVPYDEDLRRAAEVLNAGRKVAILVGAGAL--GATDEVIAVAERLG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 258 IPFAETQAGKSAIVSSHELNVGGVGETGCLAANRLAKEAD--LIIGIGTRYTDFttsskwiFQNPDVA-FLNINIarfDA 334
Cdd:PRK08273 235 AGVAKALLGKAALPDDLPWVTGSIGLLGTKPSYELMRECDtlLMVGSSFPYSEF-------LPKEGQArGVQIDI---DG 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 335 ------YKLDgVQVTADAKQSINALIDKLPPGYKTQWGDAIKQAKADFADELQRLRQVKFtdgfvpeinDNLDHDAVYAE 408
Cdd:PRK08273 305 rmlglrYPME-VNLVGDAAETLRALLPLLERKKDRSWRERIEKWVARWWETLEARAMVPA---------DPVNPQRVFWE 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 409 FIK-LTNSCLTQSQVLGIVNETIDNSAVIVGAAGSLPGDLqrtwlsksedsyhleygySCMGYEVNAAVGVKIAQPEREV 487
Cdd:PRK08273 375 LSPrLPDNAILTADSGSCANWYARDLRMRRGMMASLSGTL------------------ATMGPAVPYAIAAKFAHPDRPV 436
|
490
....*....|....*....
gi 2006413104 488 YALVGDGAFLMSH-SELVT 505
Cdd:PRK08273 437 IALVGDGAMQMNGmAELIT 455
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
469-603 |
8.46e-13 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 67.54 E-value: 8.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 469 GYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVgngmGSYGTEFrfrnpe 548
Cdd:cd02013 56 GYALPAIIGAKAAAPDRPVVAIAGDGAWGMSMMEIMTAVRHKLPVTAVVFRNRQWGAEKKNQV----DFYNNRF------ 125
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2006413104 549 tnqLNGSLIPVDFAMCAAAYGCKTYKVTTEDELRKALADA---KQQTVSTLIDIKVLP 603
Cdd:cd02013 126 ---VGTELESESFAKIAEACGAKGITVDKPEDVGPALQKAiamMAEGKTTVIEIVCDQ 180
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
417-602 |
1.55e-12 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 70.37 E-value: 1.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 417 LTQSQVLGIVNETIDNSAVIVGAAGSLPGDLQ-RTWLSKSEDSYHLEYGysCMGYEVNAAVGVKIAQPEREVYALVGDGA 495
Cdd:PRK07092 359 LSVAFVLQTLAALRPADAIVVEEAPSTRPAMQeHLPMRRQGSFYTMASG--GLGYGLPAAVGVALAQPGRRVIGLIGDGS 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 496 FLMSHSELVTSIQEGKKINVVLFDNMANGcinnlqvgnGMGSYGTEFRFRNPETNQLNGslipVDFAMCAAAYGCKTYKV 575
Cdd:PRK07092 437 AMYSIQALWSAAQLKLPVTFVILNNGRYG---------ALRWFAPVFGVRDVPGLDLPG----LDFVALARGYGCEAVRV 503
|
170 180
....*....|....*....|....*..
gi 2006413104 576 TTEDELRKALADAKQQTVSTLIDIKVL 602
Cdd:PRK07092 504 SDAAELADALARALAADGPVLVEVEVA 530
|
|
| TPP_PpyrDC |
cd03371 |
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of ... |
425-603 |
4.28e-12 |
|
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. These proteins require TPP and divalent metal cation cofactors.
Pssm-ID: 239468 [Multi-domain] Cd Length: 188 Bit Score: 65.41 E-value: 4.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 425 IVNETIDNSAVIVGAAGSLPGDLQRTWLSKSEDSYHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELV 504
Cdd:cd03371 7 IVLSRAPATAAVVSTTGMTSRELFELRDRPGGGHAQDFLTVGSMGHASQIALGIALARPDRKVVCIDGDGAALMHMGGLA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 505 TSIQEGKK--INVVlFDNMANGcinnlQVGnGMGSYGTEfrfrnpetnqlngslipVDFAMCAAAYG-CKTYKVTTEDEL 581
Cdd:cd03371 87 TIGGLAPAnlIHIV-LNNGAHD-----SVG-GQPTVSFD-----------------VSLPAIAKACGyRAVYEVPSLEEL 142
|
170 180
....*....|....*....|..
gi 2006413104 582 RKALADAKQQTVSTLIDIKVLP 603
Cdd:cd03371 143 VAALAKALAADGPAFIEVKVRP 164
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
7-191 |
1.05e-09 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 57.56 E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 7 TVAQALVKFLDNQyieidGkeIKFVHGIAaifGHGNvLGIGQALeQDPGSLRLYQGRNEQGMAHLAIGFAKQHKRqqIIA 86
Cdd:cd07039 1 TVADVIVETLENW-----G--VKRVYGIP---GDSI-NGLMDAL-RREGKIEFIQVRHEEAAAFAASAEAKLTGK--LGV 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 87 CTSSVGPGAANMVTAAATATSNRIPLLLLPGDVFASRQPDPVLQQIEQphdlsistNDAFRAVSKYWDRVLRPEQLMSAC 166
Cdd:cd07039 67 CLGSSGPGAIHLLNGLYDAKRDRAPVLAIAGQVPTDELGTDYFQEVDL--------LALFKDVAVYNETVTSPEQLPELL 138
|
170 180
....*....|....*....|....*
gi 2006413104 167 INAMRvlTDPAETGAVTIALPQDVQ 191
Cdd:cd07039 139 DRAIR--TAIAKRGVAVLILPGDVQ 161
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
475-601 |
3.77e-08 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 53.37 E-value: 3.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 475 AVGVKIAQPEReVYALVGDGAFLmsH---SELVTSiQEGKKINVVLfdnmangcINNlqvgNGmgsyGTEFRF-----RN 546
Cdd:cd02009 60 ALGIALATDKP-TVLLTGDLSFL--HdlnGLLLGK-QEPLNLTIVV--------INN----NG----GGIFSLlpqasFE 119
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2006413104 547 PETNQLNGSLIPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKV 601
Cdd:cd02009 120 DEFERLFGTPQGLDFEHLAKAYGLEYRRVSSLDELEQALESALAQDGPHVIEVKT 174
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
469-598 |
1.15e-07 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 54.85 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 469 GYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTE----FRF 544
Cdd:PRK07586 388 GQGLPLATGAAVACPDRKVLALQGDGSAMYTIQALWTQARENLDVTTVIFANRAYAILRGELARVGAGNPGPRaldmLDL 467
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2006413104 545 RNPetnqlngsliPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLID 598
Cdd:PRK07586 468 DDP----------DLDWVALAEGMGVPARRVTTAEEFADALAAALAEPGPHLIE 511
|
|
| TPP_ComE |
cd03372 |
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins ... |
468-604 |
2.06e-06 |
|
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins similar to Methanococcus jannaschii sulfopyruvate decarboxylase beta subunit (ComE). M. jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits, which catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. ComDE requires TPP and divalent metal cation cofactors.
Pssm-ID: 239469 [Multi-domain] Cd Length: 179 Bit Score: 48.44 E-value: 2.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 468 MGYEVNAAVGVKIAQPeREVYALVGDGAFLMSHSELVTSIQEG-KKINVVLFDNmangcinnlqvgngmGSYGtefrfrn 546
Cdd:cd03372 44 MGLASSIGLGLALAQP-RKVIVIDGDGSLLMNLGALATIAAEKpKNLIIVVLDN---------------GAYG------- 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 547 pET-NQLNGSLIPVDFAMCAAAYGCK-TYKVTTEDELRKALADAKQQTVstLIDIKVLPK 604
Cdd:cd03372 101 -STgNQPTHAGKKTDLEAVAKACGLDnVATVASEEAFEKAVEQALDGPS--FIHVKIKPG 157
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
459-602 |
5.91e-06 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 49.31 E-value: 5.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 459 YHLEYGYSCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLfdnmangcINNlqvgngmGSY 538
Cdd:PLN02573 421 YEFQMQYGSIGWSVGATLGYAQAAPDKRVIACIGDGSFQVTAQDVSTMIRCGQKSIIFL--------INN-------GGY 485
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2006413104 539 GTEFRFRNPETNQL-NGSLIPVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLIDIKVL 602
Cdd:PLN02573 486 TIEVEIHDGPYNVIkNWNYTGLVDAIHNGEGKCWTAKVRTEEELIEAIATATGEKKDCLCFIEVI 550
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
91-598 |
9.07e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 48.72 E-value: 9.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 91 VGPGAANMVTAAATATSNRIPLLLLPGDVFASRQP--DPVLQQIeqphdlsistnDAF-RAVSKYWDRVLRPEQLMSACI 167
Cdd:PRK12474 76 LGPGLANGLANLHNARRAASPIVNIVGDHAVEHLQydAPLTSDI-----------DGFaRPVSRWVHRSASAGAVDSDVA 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 168 NAMRVlTDPAETGAVTIALPQDVqaeAYDfPVSFLQKRVHRIERTPPTQEMLADAVKLITSKKKPLIICGGGVRYSQACR 247
Cdd:PRK12474 145 RAVQA-AQSAPGGIATLIMPADV---AWN-EAAYAAQPLRGIGPAPVAAETVERIAALLRNGKKSALLLRGSALRGAPLE 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 248 SLQHFAEKFGIP-FAETQAGKSaivsshELNVGGV--------GETGclaaNRLAKEADLIIGIGTRytdfttsskwifq 318
Cdd:PRK12474 220 AAGRIQAKTGVRlYCDTFAPRI------ERGAGRVpieripyfHEQI----TAFLKDVEQLVLVGAK------------- 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 319 nPDVAFLniniarfdAYKldgvqvtadAKQSINAlidklPPG----YKTQWGDAIKQAKADFADELQRLRQ-VKFTDGFV 393
Cdd:PRK12474 277 -PPVSFF--------AYP---------GKPSWGA-----PPGceivYLAQPDEDLAQALQDLADAVDAPAEpAARTPLAL 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 394 PEI-NDNLDHDAVyaefikltnscltqSQVlgIVNETIDNSAVIVGAAGS-LPGDLQrtwLSKSEDSYHLEYGYSCMGYE 471
Cdd:PRK12474 334 PALpKGALNSLGV--------------AQL--IAHRTPDQAIYADEALTSgLFFDMS---YDRARPHTHLPLTGGSIGQG 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 472 VNAAVGVKIAQPEREVYALVGDGAFLMSHSELVTSIQEGKKINVVLFDNMANGCINNLQVGNGMGSYGTE----FRFRNP 547
Cdd:PRK12474 395 LPLAAGAAVAAPDRKVVCPQGDGGAAYTMQALWTMARENLDVTVVIFANRSYAILNGELQRVGAQGAGRNalsmLDLHNP 474
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 2006413104 548 EtnqlngslipVDFAMCAAAYGCKTYKVTTEDELRKALADAKQQTVSTLID 598
Cdd:PRK12474 475 E----------LNWMKIAEGLGVEASRATTAEEFSAQYAAAMAQRGPRLIE 515
|
|
| PRK06163 |
PRK06163 |
hypothetical protein; Provisional |
432-520 |
1.02e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 235721 [Multi-domain] Cd Length: 202 Bit Score: 46.75 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 432 NSAVIVGAAGSLPGDLqrtWLS--KSEDSYHLeygySCMGYEVNAAVGVKIAQPEREVYALVGDGAFLMSHSELVT-SIQ 508
Cdd:PRK06163 28 DEEAVIGGIGNTNFDL---WAAgqRPQNFYML----GSMGLAFPIALGVALAQPKRRVIALEGDGSLLMQLGALGTiAAL 100
|
90
....*....|..
gi 2006413104 509 EGKKINVVLFDN 520
Cdd:PRK06163 101 APKNLTIIVMDN 112
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
44-188 |
2.02e-04 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 42.33 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 44 LGIGQALEQDPGsLRLYQGRNEQGMAHLAIGFAKQHKRQqiiACTSSVGPGAANMVTAAATATSNRIPLLLLPGDVfasr 123
Cdd:cd06586 24 SSLLDALREGDK-RIIDTVIHELGAAGAAAGYARAGGPP---VVIVTSGTGLLNAINGLADAAAEHLPVVFLIGAR---- 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2006413104 124 qpdPVLQQIEQPHDlSISTNDAFRAVSKYWDRVLRPEQLMSACINAMRvlTDPAETGAVTIALPQ 188
Cdd:cd06586 96 ---GISAQAKQTFQ-SMFDLGMYRSIPEANISSPSPAELPAGIDHAIR--TAYASQGPVVVRLPR 154
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
467-522 |
9.03e-04 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 40.72 E-value: 9.03e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2006413104 467 CMGYEVNAAVGVKIAQPEREVYALVGDGAFLmsHS---ELVTSIQEGKKINVVLFDNMA 522
Cdd:cd02008 52 CMGASIGVAIGMAKASEDKKVVAVIGDSTFF--HSgilGLINAVYNKANITVVILDNRT 108
|
|
| TPP_ComE_PpyrDC |
cd02001 |
Thiamine pyrophosphate (TPP) family, ComE and PpyrDC subfamily, TPP-binding module; composed ... |
430-603 |
1.58e-03 |
|
Thiamine pyrophosphate (TPP) family, ComE and PpyrDC subfamily, TPP-binding module; composed of proteins similar to sulfopyruvate decarboxylase beta subunit (ComE) and phosphonopyruvate decarboxylase (Ppyr decarboxylase). Methanococcus jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits which, catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. Ppyr decarboxylase is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. Ppyr decarboxylase and ComDE require TPP and divalent metal cation cofactors.
Pssm-ID: 238959 [Multi-domain] Cd Length: 157 Bit Score: 39.78 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 430 IDNSAVIVGAAGSLPgdLQRTWLSKSEDSYHLE------YGYSCMGYEVNAAVGVKIAQPeREVYALVGDGAFLMSHSEL 503
Cdd:cd02001 2 IAAIAEIIEASGDTP--IVSTTGYASRELYDVQdrdghfYMLGSMGLAGSIGLGLALGLS-RKVIVVDGDGSLLMNPGVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2006413104 504 VT-SIQEGKKINVVLFDNMANGCINNLqvgngmgsygtefrfRNPETNqlngslipVDFAMCAAAYGCKTYKVTTEDELR 582
Cdd:cd02001 79 LTaGEFTPLNLILVVLDNRAYGSTGGQ---------------PTPSSN--------VNLEAWAAACGYLVLSAPLLGGLG 135
|
170 180
....*....|....*....|.
gi 2006413104 583 KALADAKQQTVSTLIDIKVLP 603
Cdd:cd02001 136 SEFAGLLATTGPTLLHAPIAP 156
|
|
| |
