|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
59-517 |
4.44e-94 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 294.08 E-value: 4.44e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 59 LDASIFALALPGVAELLLDPVMGAVDTAFIGRLtgdGAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAkisASGGR 138
Cdd:cd13136 1 LHREILALALPAILSNITVPLLGLVDTAVVGHL---GSAAYLGAVALGTTIFNTLFWLFGFLRMGTTGLVAQ---ALGAG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 139 DSAEGRRAakktVGSAMALALALGFATMgimeVFTDDLLAFCGAsheaLLNPSEDllpdadvptikgMLEYGEDYLRIRA 218
Cdd:cd13136 75 DREEAIAL----LVRALLLALAIGLLLI----LLQSPLLALALL----LLGASAA------------VAALARQYLRIRI 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 219 ASLPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGpfpaFDVAGAATATTVAEWVGAIWFWKLMMDE 298
Cdd:cd13136 131 LGAPAVLLNYVATGWFRGLQDTRTPLILQIVGNVVNIVLDPLFVFGLG----WGVAGAALATVIAQYLGALLGLWLLRRR 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 299 EILDFQSVFRlPDESNDDLGTLVSGSTSQLARTVLLQTVLVRATSTAAMLGAA--GAHQVCLQAWWVTLFGLDSVAVSAQ 376
Cdd:cd13136 207 VRLLGKSLSR-RLPSKAALKRLFKLNRDIFIRTLALLAAFLFFTALAARLGDVilAANQILLQFWLLSSYFLDGFAYAAE 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 377 ALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGDG 456
Cdd:cd13136 286 ALVGRALGAGDRKAARRVARRLLQWGLGLGVLLALLFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALAFVLDG 365
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 145345902 457 VFQGSADFDFLAKAMAISAGGGILALTAAGQMEGasLTSVWLGMATLMFGRAATLGWRYFK 517
Cdd:cd13136 366 IFIGATDTRYLRNSMLVSLAVFLPLLFLLVPLWG--NHGLWLALILFMLLRGLTLALRLPR 424
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
63-514 |
4.20e-50 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 178.41 E-value: 4.20e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAKIsasGGRDsae 142
Cdd:COG0534 10 LLRLALPIILGNLLQSLYGLVDTIFVGRL----GTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQAL---GAGD--- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 gRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEallnpsedllpdadvptikgMLEYGEDYLRIRAASLP 222
Cdd:COG0534 80 -REEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPE--------------------VLALARDYLRIILLGLP 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 223 ACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGigpfPAFDVAGAATATTVAEWVGAIWF-WKLMMDEEIL 301
Cdd:COG0534 139 FLLLFNVLNGILRGLGDTKTPMIIMLIGNVLNIVLDPLLIFG----GGLGVAGAALATVISQAVSALLLlYYLFRKRSLL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 302 DFQSVFRLPDesNDDLGTLVSGSTSQLARTVLLQTVLVRATSTAAMLGAAG--AHQVCLQAWWVTLFGLDSVAVSAQALV 379
Cdd:COG0534 215 RLRLRDLRPD--RKILKRILRIGLPAGLQQLAESLGFLVLNALVARLGTAAvaAYGIALRIESLAFMPALGLGQAAQPLV 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 380 AASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGDGVFQ 459
Cdd:COG0534 293 GQNLGAGDYDRARRAARLALLLALGIGLLLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALR 372
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 145345902 460 GSADFDFLAKAMAISAGGGILALTAAGQMEGASLTSVWLGMATLMFGRAATLGWR 514
Cdd:COG0534 373 GAGDTRFPMIISLLRLWLVRLPLAYLLAFLGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
63-519 |
1.02e-38 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 147.27 E-value: 1.02e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLTgdgaAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAakiSASGGRDsae 142
Cdd:cd13137 3 IWSLAWPVILENLLQTLVGLVDVFMVGRLG----AEAIAAVGLATQVLWLLLVLNMALGTGTVALVS---QSYGAGD--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 gRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEALlnpsedllpdadvptikgmlEYGEDYLRIRAASLP 222
Cdd:cd13137 73 -YERARRALGQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVI--------------------ALALTYLRIVLLGIP 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 223 ACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIW-FWKLMMDEEIL 301
Cdd:cd13137 132 FFFLSLVGNAALRGAGDTKTPMYIMIIVNVLNIVLDYVLIFGLWGFPGLGVAGAALATVISRVVGALLlLFLLLRGRLPI 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 302 DFQSVFRLPDESND-DLGTL-----VSGSTSQLARTVLLqtVLVRATSTAAMlgaaGAHQVCLQAWWVTLFGLDSVAVSA 375
Cdd:cd13137 212 KISFKGFRLDRKIIkKLLRIglpagLEQLLRSLGFLVLL--AIVASYGTAAL----AAYQIGLRIESLAFMPGFGFSMAA 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 376 QALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGD 455
Cdd:cd13137 286 STLVGQNLGAGDPDEARRYGKRALRLGVLFMGLLGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLS 365
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 145345902 456 GVFQGSADFDFLAKAMAISAGGGILALTA-AGQMEGASLTSVWLGMATLMFGRAATLGWRYFKDD 519
Cdd:cd13137 366 GALRGAGDTRPPLIINLISMWLVRLPLAYlLGFVLGLGLTGIWLAMFVDTIVRAILLLYRFRKGK 430
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
69-442 |
7.71e-31 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 123.12 E-value: 7.71e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 69 PGVAELLLDPVMGAVDTAFIGRLTGDgaaeALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAKISAsggrdsaEGRRAAK 148
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPV----DLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGA-------GNYQRLG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 149 KTVGSAMALALALGFATMGIMEVFTDDLLAFCGASheallnpsedllpdadvptiKGMLEYGEDYLRIRAASLPACLIVM 228
Cdd:TIGR00797 70 RQAQQSLLLALLLGLPVLLVGYFFIDPLLSLMGAD--------------------GEVAELAQDYLRILILGIPAYLLNF 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 229 VGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIgpFPAFDVAGAATATTVAEWVGA-IWFWKLMMDEEILDFQSVF 307
Cdd:TIGR00797 130 VLRGFLRGQGDTKTPMYITLIGNVINIILNYILIFGK--FGFLGIVGAALATVISYWLMFlLLLYYIKKAKKIGLKWEGL 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 308 RLPDESNddLGTLVSGSTSQLARTVLLQTVLVRATSTAAMLGAAG--AHQVCLQAWWVTLFGLDSVAVSAQALVAASLGK 385
Cdd:TIGR00797 208 LKPDWEV--LKRLLKLGLPIAFRVILESLSFALLALLVARLGSIAlaAHQIALNVESLLFMPAFGFGIAVSILVGQALGA 285
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 145345902 386 NDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILS 442
Cdd:TIGR00797 286 GDPKRAKEVARVALKLSLLLGLVLAIILILFREFIARLFTNDPEVLELAAIYLIFVA 342
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
57-517 |
8.75e-24 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 104.20 E-value: 8.75e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 57 ELLDASI----FALALPGVAELLLDPVMGAVDTAFIGRLtgdgaaealGGLAVSTTCFTFCFkLFNFLAVVTGPLVAAKI 132
Cdd:cd13142 3 NILEGSIlrtlLKLAWPIIVSNLLQVAYNLADTFWLGRL---------GADAVAAPSISWPL-IFLFISLGGGLTVAGTA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 133 SAS---GGRDSAEGRRAAKKTVGsaMALALALGFATMGImeVFTDDLLAfcgasheALLNPSEDLLPDAdvptikgmley 209
Cdd:cd13142 73 LVAqytGAGDYDKANKVAGQTFS--FVIILSLILAVLGY--ILSRPLLL-------LLIGAPEEVYPLA----------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 210 gEDYLRIRAASLPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAI 289
Cdd:cd13142 131 -LAYLRIIFLGLPFMFIFFVFNSLLRGIGDTKTPMKIMFGSVLLNVILDPLLIFGIGPFPGLGVAGAALATVISRGIAAV 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 290 W-----FW-----KLMMDEEILDFQSV---FRLpdesndDLGTLVSGSTSQLARTVLlqTVLVRATSTAAmLGAAGAHQV 356
Cdd:cd13142 210 IglyllFKgrvglKISLRDLKPDWEWLkkiFRI------GLPSSIEQSARALGFTVM--TALVAGFGTVV-VAAYGIGNR 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 357 CLQAWWVTLFGLdSVAVSaqALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAAT 436
Cdd:cd13142 281 IISLVFLPAFGL-ARATS--TMVGQNLGAGQIDRAEEIVKKAALLIFLILVIGGVLAFLFAEPIVRVFINDPEVIKEGAD 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 437 PIRILSLLQPLNSAVFVGDGVFQGSADfdfLAKAMAIS----AGGGILALTAAGQMEGASLTSVWLGMATLMFGrAATLG 512
Cdd:cd13142 358 FLRIVAPSFPFFGLFQVINGAFRGSGH---TLTAMIISilrlWVIRIPLAYLLAYVLGLGVTGIWIAMAISNIV-AALIA 433
|
....*
gi 145345902 513 WRYFK 517
Cdd:cd13142 434 LAWFK 438
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
62-517 |
4.25e-22 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 99.11 E-value: 4.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 62 SIFALALPGVAELLLDPVMGAVDTAFIGRLtGDGAAEALGglaVSTTCFTFCFKLFNFLAVVTGPLVAAKIsasGGRDsa 141
Cdd:cd13134 4 SLFALAWPIFIELLLQMLLGTIDTFMLSRY-SDNAVAAVG---VANQILFLLILIFSFISTGTSILIAQYL---GAKD-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 142 egRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAfcgasheaLLNPSEDLLpdadvptikgmlEYGEDYLRIRAASL 221
Cdd:cd13134 75 --KKKARQIAGVALLFNLLLGLVFSLLLLFFGAELLR--------LMGLPPELL------------ALGSTYLRIVGGSL 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 222 PACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIWFWKLMmdeeIL 301
Cdd:cd13134 133 FLQALSLTLSAILRSHGRTKIPMYVSLIMNILNIVGNYLLIFGWFGLPKLGVAGVAISTVISRAVGLVLLFILL----FR 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 302 DFQSVFRLPDESNDDLGTLV--------SGSTS---QLARTVLlqtvlvraTSTAAMLGAAG--AHQVCLQ-AWWVTLFG 367
Cdd:cd13134 209 KLKIRFRLKDLRPFPKKLLKkilkiglpSAGEElsyNLSQTVI--------TAFIARLGTAAlaARTYASNiSMFVFLFS 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 368 LdSVAVSAQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPL 447
Cdd:cd13134 281 L-AIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVSLAVALLLALFREPILGLFTDDPEIIALGKTLLLISILLEPG 359
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 145345902 448 NSAVFVGDGVFQGSADFDFLAKAMAISAGGGILALT-AAGQMEGASLTSVWLGMATLMFGRAATLGWRYFK 517
Cdd:cd13134 360 RAFNIVLIGSLRAAGDARFPVLIGIISMWGISVPLAyLLGIVLGLGLLGVWIAFAADEWVRGIIMLWRWRS 430
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
67-512 |
1.07e-21 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 97.78 E-value: 1.07e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 67 ALPGVAELLLDPVMGAVDTAFIGRLTGDgaaeALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAkisasggRDSAEGRRA 146
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGD----ALAAVGLAFPLIALLIALGVGLSVGTSALISQ-------AIGAGDEEK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 147 AKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEallnpsedllpdadvptikgMLEYGEDYLRIRAASLPACLI 226
Cdd:cd12082 70 ARRVLVQSIVLAILLGLLLAALLLFFSPLILSLLGAEEE--------------------VIELAATYLTILILGLPITFL 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 227 VMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPfPAFDVAGAATATTVAEWVGAIWFWkLMMDEEILDFQSV 306
Cdd:cd12082 130 GAVLSGILQGEGDTRTAMIISVLSNLLNILLDPLLIFGLGP-PELGIAGAALATVISYVIGALLLL-IYLRKGKKILKFK 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 307 FRLPDESNDDLGTLVSGSTSQLARTVLLQTVLVRATSTAAMLG---AAGAHQVCLQAWWVTLFGLDSVAVSAQALVAASL 383
Cdd:cd12082 208 LSLLKPDLELLRRLLRIGLPSAIQNSLLSLGLLIIVAIVAAFGgaaALAAYTVAFRIASLAFMPALGLAQAALPVVGQNL 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 384 GKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGDGVFQGSAD 463
Cdd:cd12082 288 GAGNFDRARRITWVALLIGLLIGAVLGLLILLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGR 367
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 145345902 464 FDFLAKAMAISAGGGILALTAAGQMEGASLTSVWLGMATLMFGRAATLG 512
Cdd:cd12082 368 TLKSLIVSLLSYWVVRLPLAYVLAYLGLGLYGIWLALVISLILAALVLL 416
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
62-501 |
2.72e-16 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 81.35 E-value: 2.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 62 SIFALALPGVAELLLDPVMGAVDTAFIGRLTGdgaAEALGGLAVSTTCFTFcfklfnFLAVVTGPLVAAKISAS---GGR 138
Cdd:cd13138 4 TLLLFALPLLLSNLLQQLYNLVDLLIVGQFLG---VAALAAVSNGSPIIFL------LTAIGMGLSMGGTILISqyiGAK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 139 DsaegRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEALlnpsedllpdadvptikgmlEYGEDYLRIRA 218
Cdd:cd13138 75 D----EEKAKKAVGTLLVLFLILGIVLTILGLLFAPPILRLMNTPAEIL--------------------ELAVSYLRICF 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 219 ASLPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGpfpaFDVAGAATATTVAEWVGAIW-FWKLMMD 297
Cdd:cd13138 131 LGIPFIFGYNAYSAILRGLGDSKTPLYFVIIACVLNIILDLLFIAVFH----MGVAGAALATVIAQAISVLLaLYYLRKK 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 298 EEILDFqsVFRLPDESNDDLGTLVSgstsqLARTVLLQTVLVRA-----TSTAAMLG--AAGAHQVCLQAWWVTLFGLDS 370
Cdd:cd13138 207 KLPFKL--SLKDFRFDKEILKEILK-----IGLPSALQQSLVSIsfliiNSIVNSYGvvASAAYGIANKINSFAFLPPSA 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 371 VAVSAQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSA 450
Cdd:cd13138 280 IGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLIIILLVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGI 359
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 145345902 451 VFVGDGVFQGSADFDFlakAMAISAGGG----ILALTAAGQMEGASLTSVWLGMA 501
Cdd:cd13138 360 LFVFNGLFRGLGKTKF---PMIISILRLwlvrIPLAYLLSRLTGLGLFGIWLAMP 411
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
59-443 |
3.09e-16 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 81.12 E-value: 3.09e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 59 LDASIFALALPGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAKIsasGGR 138
Cdd:cd13139 12 LNRAIFLLAIPMVLEMVMESLFAVVDLYFVSRL----GALAIATVGLTESVLTIVYSIAIGLSMAATALVARRI---GEK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 139 DSAEGRRAAKKTVGSAMALALALGFATMgimeVFTDDLLAFCGASHEALlnpsedllpdadvptikgmlEYGEDYLRIRA 218
Cdd:cd13139 85 DPEGAGFAAVQAILLGVALSLILSILGY----FFAEDILSLMGASPAVI--------------------AEGYGYTRIMF 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 219 ASLPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIW-FWKLMMD 297
Cdd:cd13139 141 GGNGFIMLLFLINGIFRGAGDAAIAMRSLWLANGLNIILDPLFIFGLGPIPAMGVTGAAIATTIGRSIGVLYqLYHLFKG 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 298 EEI---------LDFQSVFRLPDESNDDLGTLVSGSTSQLartvllqtVLVRATSTAAMLGAAGaHQVCLQAWWVTLFGL 368
Cdd:cd13139 221 KGRiqirrrhlkLDWAIIKKIIKIAVGGILQFLIASSSWI--------FLVRIIAEFGSTALAG-YTIAIRIIMFALLPA 291
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 145345902 369 DSVAVSAQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSL 443
Cdd:cd13139 292 WGLSNAAATLVGQNLGAGQPDRAEKSVWRAGKYNMVFLGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEALRIISL 366
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
62-311 |
2.96e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 74.87 E-value: 2.96e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 62 SIFALALPGVAELLLDPVMGAVDTAFIGRLtGDGAAEALGGLAVsttcFTFCFKLFNFLAVV-TGPLVAAKIsasGGRDS 140
Cdd:cd13140 6 TLLRLALPIMGTSFIQMAYNLTDMFWVGRL-GSDAVAAVGTAGF----FVWLAYALALLSKIgAQVKVSQSI---GAKDE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 141 AEgrraAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGasheallnpsedlLPDADVptikgmLEYGEDYLRIRAAS 220
Cdd:cd13140 78 KE----ARKYARNALQLNLLLGILYGLLLLLFAKPLIGFFN-------------LGDAEV------ISLAITYLRIVALG 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 221 LPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIWFWKLMM-DEE 299
Cdd:cd13140 135 LIFSFLNPVFTGIFNALGDSKTPFIINAIGLVLNIILDPLLIFGFGPFPALGVAGAALATVLAQAIVFLLFLYALKkKKG 214
|
250
....*....|..
gi 145345902 300 ILDFQSVFRLPD 311
Cdd:cd13140 215 LFLKIRILKRPD 226
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
63-517 |
3.83e-14 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 74.46 E-value: 3.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAkisasggRDSAE 142
Cdd:cd13131 5 LLRLALPILIAQLAQMAMGFVDTVMAGRL----GADDLAAVALGSSLWFPVFTFGMGLLLAVTPLVAQ-------AHGAG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 GRRAAKKTVGSAMALALALGFATMGIMeVFTDDLLAFcgashealLNPSEDLLPDADvptikgmleygeDYLRIRAASLP 222
Cdd:cd13131 74 DRRRIRRAVRQGLWLALLLSLPLMLLL-WLAPPILPL--------MGQEPEVAAIAR------------GYLLALAWGIP 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 223 ACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIWFWKLMM-DEEIL 301
Cdd:cd13131 133 PALLFQVLRSFLDALGRTRPAMVITLLALVLNIPLNYVLIFGKFGLPALGGAGAGLATAIVYWLMFLALAFYIRrHKRFR 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 302 DFQSVFRLPDESNDDLGTLVSGSTSqLARTVLLQTVLVRATS-TAAMLGAA--GAHQVCLQ----AWWVTLfgldSVAVS 374
Cdd:cd13131 213 RYRLFARFWRPDWARLKELLRLGLP-IGLTIFFEVSLFAAVAlLMGRLGTTvlAAHQIALNfaslLFMVPL----GISMA 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 375 AQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVG 454
Cdd:cd13131 288 ATVRVGFALGAGDPADARRAGLVGLGLGVGFAALTALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVA 367
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145345902 455 DGVFQGSADFDFLAKAMAIS------AGGGILALTAagqmeGASLTSVWLGMATLMFGRAATLGWRYFK 517
Cdd:cd13131 368 AGALRGYKDTRVPFLLALISywgiglPLGYLLAFTT-----GLGAFGVWIGLIIGLALAAILLLWRFRR 431
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
63-517 |
4.31e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 74.49 E-value: 4.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLTgdgaAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAakisasggRDSAE 142
Cdd:cd13133 7 ILKIALPLVLSMLSQTVMGFTDRAFLGRLS----EVALAASGPAGVLYFAILMLFFGLSSGVQVFVA--------QYNGA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 GRRA-AKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEallnpsedllpdadvptikgMLEYGEDYLRIRAASL 221
Cdd:cd13133 75 GRYSrIGRVLWQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPE--------------------VQALEVEYFRIRILGA 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 222 PACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIWFWKLMM---DE 298
Cdd:cd13133 135 PFSLLGAALRAFFSGIGRTRVVMVANLVMVVVNIVLDYALIFGKLGFPAMGIAGAAIATVIAEAVSLLFFLLLLFrrkNR 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 299 EILDFQSVFRLpdesndDLGTLvsGSTSQLARTVLLQTVLVRATSTA--AMLGAAG-----AHQVCLQawWVTLFGLDSV 371
Cdd:cd13133 215 RRFGLRRAWRF------DRELL--RRILRLGLPSGLQFFLDVGAFTVffLLIGRLGttelaATNIVFS--INSLAFLPMI 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 372 AVS--AQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTND---AEIAAQAATPIRILSLLQP 446
Cdd:cd13133 285 GLGiaVSSLVGQALGAGRPDLAMRVTRRGLKLALAYMLLLGILFLLFPELLLSIFTPGadfALIAELAVPLLRFVAAYIL 364
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 145345902 447 LNSAVFVGDGVFQGSADFDFLAKAMAISAGGGILALTAAGQMEGASLTSVWLGMATLMFGRAATLGWRYFK 517
Cdd:cd13133 365 FDALALVFAGALRGAGDTRFVMLAELIVAWLYLLPPAYLLVVLGAGLAGAWTVETVYVIVLALIFLLRFRS 435
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
63-482 |
5.10e-13 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 71.00 E-value: 5.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLTGdgaAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAKIsasGGRDsae 142
Cdd:cd13143 6 FLKFALPAIIGMLVNGLYNIVDGIFVGHGVG---ALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRL---GAGD--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 gRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASheallnpsEDLLPdadvptikgmleYGEDYLRIRAASLP 222
Cdd:cd13143 77 -REKANRIFSTALLLSLILGLLLTILGLLFLDPLLRLLGAS--------GELLP------------YAVDYLRIILLGAP 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 223 ACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGpfpaFDVAGAATATTVAEWVGAIWFW---------- 292
Cdd:cd13143 136 FTILSSVLNNLLRAEGKPKLAMLGMLIGAVLNIILDPLFIFVLG----LGIAGAALATVIAQLISLLLLLlyffrgksll 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 293 KLMMDEEILDFQSVFRLpdesnddLGTLVSGSTSQLArTVLLQTVLVRATSTAAMLGAAGAHQVCLQAWWVTLFGLDSVA 372
Cdd:cd13143 212 KLSLLRFKLSLKIIKEI-------LALGFPSFLMQLS-SSVVTIVLNLTLLGYGGDIGVAAFGIVTRILTFLFLPLIGLS 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 373 VSAQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVF 452
Cdd:cd13143 284 QGLQPIIGYNYGAGNYDRVKQALKLALIVALIYGLVLFLILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGINI 363
|
410 420 430
....*....|....*....|....*....|
gi 145345902 453 VGDGVFQGSADfdfLAKAMAISAGGGILAL 482
Cdd:cd13143 364 VLSGYFQAIGK---AKRAALLSLLRQGLFL 390
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
63-270 |
6.59e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 67.71 E-value: 6.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLtGDGAAEALGglavsttcFTFCFKLF-NFLAVVTGPLVAAKISASGGrdsA 141
Cdd:cd13149 11 LIKLTLPMIFGILAMLIFNLTDTFFVGKL-GTKELAAIS--------FTFPVVLFlNSLTIGLGIGASAVISRAIG---A 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 142 EGRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEallnpsedllpdadvptikgMLEYGEDYLRIRAASL 221
Cdd:cd13149 79 GDRNKAKRLATDSLILSLLLSVIVSLLGLFTIPPLFSLLGASGE--------------------ILPLIVEYMAIWYLGL 138
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 145345902 222 PACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPA 270
Cdd:cd13149 139 VFLVLPMVGNAIIRATGDTKRPSLVMLGAALVNVILDPILIFGFGPIPG 187
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
69-260 |
3.67e-11 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 61.81 E-value: 3.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 69 PGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAkisASGGRDsaegRRAAK 148
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHL----GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQ---ALGAGN----FKRAG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 149 KTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEallnpsedllpdadvptikgMLEYGEDYLRIRAASLPACLIVM 228
Cdd:pfam01554 70 VALRQGLILGLLLSLPIALLVLLFSEPILSLFGQDEE--------------------VLALAKRYLRILILGIPFYALQF 129
|
170 180 190
....*....|....*....|....*....|..
gi 145345902 229 VGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPF 260
Cdd:pfam01554 130 VLSGFLRGQGDTKPPMYINIISLLLNIPLNYL 161
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
342-479 |
4.53e-10 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 58.35 E-value: 4.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 342 TSTAAMLGAA--GAHQVCLQAWWVTLFGLDSVAVSAQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQ 419
Cdd:pfam01554 17 TLFVGHLGAValAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGLLLSLPIALLVLLFSEP 96
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 420 LPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGDGVFQGSADFDFLAKAMAISAGGGI 479
Cdd:pfam01554 97 ILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNI 156
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
60-513 |
3.24e-09 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 59.37 E-value: 3.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 60 DASIFALALPGVAELLLDPVMGAVDTAFIGRLTgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAakiSASGGRD 139
Cdd:PRK10367 8 DKALWRLALPMIFSNITVPLLGLVDTAVIGHLD---SPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTA---QAFGAKN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 140 saegRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASheallnpsedllpdadvptiKGMLEYGEDYLRIRAA 219
Cdd:PRK10367 82 ----PQALARALVQPLLLALGAGALIALLRTPLIDLALHIVGGS--------------------EAVLEQARRFLEIRWL 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 220 SLPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIWFWKLMMDEE 299
Cdd:PRK10367 138 SAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIVLDLWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKVLKLRG 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 300 IldfqSVFRLPDESNDDLGTLVSGSTSQLARTVLLQTVLVRATSTAAMLGA--AGAHQVCLQAWWVTLFGLDSVAVSAQA 377
Cdd:PRK10367 218 I----SLEMLKTAWRGNFRRLLALNRDIMLRSLLLQLCFGAITVLGARLGSdiIAVNAVLMTLLTFTAYALDGFAYAVEA 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 378 LVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGDGV 457
Cdd:PRK10367 294 HSGQAYGARDGSQLLDVWRAACRQSGIVALLFSLVYALAGEHIIALLTSLPQIQQLADRYLIWQVILPLVGVWCYLLDGM 373
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 145345902 458 FQGSADFDFLAKAMAISAGGGILALTAAGQMEGASLtsvWLGMATLMFGRAATLGW 513
Cdd:PRK10367 374 FIGATRAAEMRNSMAVAAAGFALTLLTLPWLGNHGL---WLALTVFLALRGLSLAA 426
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
62-460 |
2.21e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 47.15 E-value: 2.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 62 SIFALALPGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAKIsasGGRDsa 141
Cdd:cd13147 10 AIIKLSIPMIIAMLLQTLYNLVDAIWVAGL----GADALAAIGFVFPLFMIIIGLGNGLGAGASSAISRRI---GAKD-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 142 egRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASheallnpsedllpdadvptikGMLEYGEDYLRIRAASL 221
Cdd:cd13147 81 --KEGADNAAVHSILLGLIISIILTIVLLPFLEPILVLMGAG---------------------EVLDLAVDYGRIIFLGS 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 222 PACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGpfpafdvagaatattvaeW--VGAIW--------- 290
Cdd:cd13147 138 IFLIFNNVAYGILRGEGDTKRAMYAMVAGSILNIILDPIFIYTLG------------------LgiAGAAWatvismlis 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 291 -----FWKLMMDEEILDFQSVFRLPDES--NDDLGTLVSGSTSQLARTVL---LQTVLVRATSTAAMlgaagahQVCLQA 360
Cdd:cd13147 200 slvllYWFFVKKDTYVSLSLKNFKFDKKivKDILKVGIPASLEQLIMSVLmiiLNLILVIVAGTDGV-------AVYTAG 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 361 WWVTLFG---LDSVAVSAQALVAASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFT---NDAEIAAQA 434
Cdd:cd13147 273 WRIVSFAiipLIGIATAVTSVTGAAYGARNYEKLKTAYNYSIKLGLIIELIIAILIFIFAPQIAYLFTyseESAHLAPEI 352
|
410 420
....*....|....*....|....*.
gi 145345902 435 ATPIRILSLLQPLNSAVFVGDGVFQG 460
Cdd:cd13147 353 VAFLRIMCLFLPFVPFGMMSSSMFQG 378
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
63-271 |
2.71e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 46.84 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLTGDGAAealgglAVSTTcftfcFKLFNF-LAVVTGplVAAKISASGGRDSA 141
Cdd:cd13144 10 LLTMSIPAMISMLFQALYNIVDSIFVARLGENALT------AVSLA-----FPIQNLmIAVAVG--TGVGVNALLSRSLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 142 EGRRA-AKKTVGSAMALALALG--FATMGImevftddllaFCGASHEALLNPSEDLLpdadvptikgmlEYGEDYLRIRA 218
Cdd:cd13144 77 EKDQKeANKAANNGLLLALLSYllFLLLGL----------FGVKPFFRLFTDDPEIL------------EYGYAYLSWCV 134
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 145345902 219 ASLPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAF 271
Cdd:cd13144 135 IFSFGMFFQILCEKVLQSTGNTITPMIAQLIGAIINIILDPILIFGLFGFPAM 187
|
|
| PRK10189 |
PRK10189 |
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
63-295 |
3.59e-05 |
|
EmmdR/YeeO family multidrug/toxin efflux MATE transporter;
Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 46.27 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLTGDgaAEALGGLAVSTTCFTFCFklfnFLAVVTGPLVAAKISAsGGRDSAE 142
Cdd:PRK10189 31 ITPLAVPIFIENLCVLLMGVLSTFLVSWLGKE--AMAGVGLADSFNMVIMAF----FAAIDLGTTVVVAFSL-GKRDRRR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 GRRAAKKTvgsamalalalgfatMGIMEVFTDDLLAFCGASHEALLnpseDLLPDADVPTIKGMleyGEDYLRIRAASLP 222
Cdd:PRK10189 104 ARAAARQS---------------LVIMTLFAVLLAVLIHFFGEQII----DLVAGDATPEVKAL---ALTYLELTVWSYP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 145345902 223 ACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIW-FWKLM 295
Cdd:PRK10189 162 AAAITLIGSGALRGAGNTKIPLLINGGMNILNIIISSILIYGLFSWQGLGFVGAGLGLTISRYIGAVAiIWVLM 235
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
83-460 |
5.82e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 45.67 E-value: 5.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 83 VDTAFIGRLTgdgaAEALGGLAVSTTCFtfcfklFNFLAVVTGPLVA--AKISASGGRDSaegRRAAKKTVGSAMALALA 160
Cdd:cd13145 31 VDTFFAGKIS----TEALAALSLSFPIF------FIIIAIGVGIGTGttALIGNALGAGD---RRKARRYAAQGLSFGII 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 161 LGFATMGIMEVFTDDLLAFCGASHEallnpsedllpdadvptikgMLEYGEDYLRIRAASLPACLIVMVGVGAFRGLLDT 240
Cdd:cd13145 98 LAILLTVIGLFAAPPLFRLLGAEGD--------------------YLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 241 RTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAATATTVAEWVGAIW-FWKLMMDEEILDFQSVFRLPDESNddlgt 319
Cdd:cd13145 158 KSYRNFLIIGFFLNIILDPLFIFGGGGIPAMGVSGIALATIISQFIGMFYlLYKVRKSGIISGCRLRDFIPRLDV----- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 320 lvsgsTSQLARTVLlqtvlvrATSTAAMLGAAGAHQVclqAWWVTLFGLDSVA--------------------VSAQALV 379
Cdd:cd13145 233 -----YKEILKQGF-------PASLNMMTIGLGIFVI---TYFVGQFGDEAVAaygialrieqilllptiglnTAVLSIA 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 380 AASLGKNDVPGARIAADRALSWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGDGVFQ 459
Cdd:cd13145 298 GQNFGAKKYDRVRETYKKALKYGFVIMVVATVFLLFFAEPLMSLFTNDPAVIAIGAGYLRIDALIFYAYVVLFISVSVLQ 377
|
.
gi 145345902 460 G 460
Cdd:cd13145 378 G 378
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
63-249 |
8.66e-05 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 45.01 E-value: 8.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLTGdgaAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAKISAsggRDSAE 142
Cdd:cd12082 221 LLRIGLPSAIQNSLLSLGLLIIVAIVAAFGG---AAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGA---GNFDR 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 GRRAAKKtvgsAMALALALGFATMGIMEVFTDDLLAFcgasheallnpsedLLPDADVptikgmLEYGEDYLRIRAASLP 222
Cdd:cd12082 295 ARRITWV----ALLIGLLIGAVLGLLILLFPEPILSL--------------FTNDPEF------LELAVSYLRILAIYYL 350
|
170 180
....*....|....*....|....*..
gi 145345902 223 ACLIVMVGVGAFRGLLDTRTPLYVAVV 249
Cdd:cd12082 351 FVGIGYVLQAGFQAAGRTLKSLIVSLL 377
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
348-462 |
1.18e-04 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 44.87 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 348 LGAAGAHQVCLQAWW----VTLFGL--DSVAVSAQALV----------------AAS------LGKNDVPGARIAADRAL 399
Cdd:cd13132 229 LAIPSALMLCLEWWAfeilVLLAGLlpGTVALAAQSICltttsllymiplgisiAASvrvgneLGAGNPKRAKLAAIVAL 308
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145345902 400 SWGVGAGVLVGVVVFLSADQLPYIFTNDAEIAAQAATPIRILSLLQPLNSAVFVGDGVFQGSA 462
Cdd:cd13132 309 ILSLVIGVVVAILLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGCG 371
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
59-250 |
1.29e-04 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 44.42 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 59 LDASIFALALPGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAAKIsasGGR 138
Cdd:cd13137 224 IIKKLLRIGLPAGLEQLLRSLGFLVLLAIVASY----GTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNL---GAG 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 139 DSAEGRRAAKKTVGSAMALALALGFatmgIMEVFTDDLLAFcgasheallnpsedLLPDADVptikgmLEYGEDYLRIRA 218
Cdd:cd13137 297 DPDEARRYGKRALRLGVLFMGLLGL----LLFIFAPPLASL--------------FTPDPEV------IELGVLYLRIVA 352
|
170 180 190
....*....|....*....|....*....|..
gi 145345902 219 ASLPACLIVMVGVGAFRGLLDTRTPLYVAVVT 250
Cdd:cd13137 353 LSQPFLAISFVLSGALRGAGDTRPPLIINLIS 384
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
58-271 |
2.63e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 43.41 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 58 LLDASIFA----LALPGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSttcftfcFKLFNFLAVVTGPLVAAKIS 133
Cdd:cd13148 5 LLTAPILPtllrLALPNILALLVQTLVGLAETYFVGQL----GTDALAGVALV-------FPLLMLTQMMSNGAMGGGVS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 134 ASGGRDSAEGRRA-AKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEALlnpsedllpdadvptikgmlEYGED 212
Cdd:cd13148 74 SAIARALGAGDRErAEALVWHALVIALAGGLVFSLLFLLFGPALYRLLGGRGEAL--------------------DAALA 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 145345902 213 YLRIRAASLPACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAF 271
Cdd:cd13148 134 YSNVLFSGAILIWLVNLLAAALRGTGNMRVPALVTLVGAVVQIPLSPGLILGWGPLPRL 192
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
63-278 |
2.88e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 40.38 E-value: 2.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 63 IFALALPGVAELLLDPVMGAVDTAFIGRLtgdgAAEALGGLAVSTTCFTFCFKLFNFLAVVTGPLVAakiSASGGRDsae 142
Cdd:cd13141 13 IISMALPIAIGMIIQTLYFLVDLYFVGQL----GDAALAGVSLAGNVMFFVMALTQVLNVGTAALVS---HAVGRKD--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 143 gRRAAKKTVGSAMALALALGFATMGIMEVFTDDLLAFCGASHEALlnpsedllpdadvptikgmlEYGEDYLRIRAASLP 222
Cdd:cd13141 83 -QGEANAVFNQSLLLAAVLGLVVLVLGYLFGRLYLETLAADAATV--------------------EAATTYLYWFIPSLA 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 145345902 223 ACLIVMVGVGAFRGLLDTRTPLYVAVVTEIFHLGLDPFLIYGIGPFPAFDVAGAAT 278
Cdd:cd13141 142 LQFILTVLGAALRGTGIVKPFMVIQILAVLLNIILAPILITGWGTGRALGVAGAGL 197
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
147-249 |
6.98e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 39.05 E-value: 6.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145345902 147 AKKTVGSAMALALALGFATMGIMEVFTDDLLAFcgasheallnpsedLLPDADVptikgmLEYGEDYLRIRAASLPACLI 226
Cdd:cd13140 306 IRKGYKTALKIASAIGLFATLLLFFFGEPLFSL--------------FIPDPET------IAIGVDYLRILGFSQLFMCL 365
|
90 100
....*....|....*....|...
gi 145345902 227 VMVGVGAFRGLLDTRTPLYVAVV 249
Cdd:cd13140 366 EITTTGAFNGLGRTKPPAIISIV 388
|
|
| |
