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Conserved domains on  [gi|189536105|ref|XP_001919825|]
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CDK5 and ABL1 enzyme substrate 2 isoform X1 [Danio rerio]

Protein Classification

cyclin family protein( domain architecture ID 1750054)

cyclin family protein may associate with and activate its cognate cyclin-dependent kinase (CDK)

CATH:  1.10.472.10
Gene Ontology:  GO:0000079|GO:0019901|GO:0007049
PubMed:  14744433|30185601|15269391|15840440
SCOP:  4001102

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CYCLIN_SF super family cl40454
Cyclin box fold superfamily; The cyclin box is a protein binding domain that functions in ...
 384-504 1.09e-75

Cyclin box fold superfamily; The cyclin box is a protein binding domain that functions in cell-cycle and transcriptional control. It is about 100 amino acids in length, composed of five helices, and is present in cyclins, transcription initiation factor IIB (TFIIB), and retinoblastoma tumour suppressor protein (Rb). Cyclins consist of 8 classes of cell cycle regulators that function as regulatory subunits of cyclin-dependent kinases (CDKs), which are serine/threonine kinases. The catalytic activities of CDKs are modulated not only by their interactions with cyclins but also by CDK inhibitors (CKIs). CDKs, cyclins and CKIs play key roles in transcription, epigenetic regulation, metabolism, stem cell self-renewal, neuronal functions, and spermatogenesis. TFIIB is a transcription factor that binds the TATA box. Members in this superfamily contain one or two copies of the cyclin box.


The actual alignment was detected with superfamily member cd20603:

Pssm-ID: 477360  Cd Length: 121  Bit Score: 234.01  E-value: 1.09e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105 384 LTFSKIRSLKREMRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKKQEVKQLIDRLEE 463
Cdd:cd20603    1 LTLSKIRSLKREMRNVAEECNLEPVTVAMAYVYFEKLVLQGKLNKQNRKLCAGACVLLAAKISSDLKKHEVKHLIDKLEE 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 189536105 464 RFRINRKELISLEFTVLVALEMALYLPDSKVMPHYRRLVQQ 504
Cdd:cd20603   81 RFRLNRRELISFEFTVLVALELALYLPENQVLPHYRRLTQQ 121
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 2-191 1.02e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105    2 AAAACGPRGCPRTNSAKPHKELLRKSRDSRRRQAALLFLTNISLDGRPVYNLSNGLVGPREVDSRCVDVGAAVAGLPLST 81
Cdd:PHA03307  202 ASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSR 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105   82 TSSygtftqVSSSISGGAATPIPRTNVNTYPAPMSPPPALNQGSSDvfTEDGRSDPLSVQAPPlSPTAGPRNTALGSSKS 161
Cdd:PHA03307  282 PGP------ASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSS--RESSSSSTSSSSESS-RGAAVSPGPSPSRSPS 352

                         170       180       190
                  ....*....|....*....|....*....|
gi 189536105  162 PSQFPSSNPLPDPRQRTRNLSGSPGPKVSK 191
Cdd:PHA03307  353 PSRPPPPADPSSPRKRPRPSRAPSSPAASA 382
 
Name Accession Description Interval E-value
CYCLIN_CABLES2 cd20603
cyclin box found in CDK5 and ABL1 enzyme substrate 2 (CABLES2); CABLES2, also called ...
 384-504 1.09e-75

cyclin box found in CDK5 and ABL1 enzyme substrate 2 (CABLES2); CABLES2, also called interactor with CDK3 2 (Ik3-2), acts as a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. CABLES2 contains one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410306  Cd Length: 121  Bit Score: 234.01  E-value: 1.09e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105 384 LTFSKIRSLKREMRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKKQEVKQLIDRLEE 463
Cdd:cd20603    1 LTLSKIRSLKREMRNVAEECNLEPVTVAMAYVYFEKLVLQGKLNKQNRKLCAGACVLLAAKISSDLKKHEVKHLIDKLEE 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 189536105 464 RFRINRKELISLEFTVLVALEMALYLPDSKVMPHYRRLVQQ 504
Cdd:cd20603   81 RFRLNRRELISFEFTVLVALELALYLPENQVLPHYRRLTQQ 121
Cyclin_N pfam00134
Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a ...
 386-484 5.28e-06

Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.


Pssm-ID: 459686 [Multi-domain]  Cd Length: 127  Bit Score: 45.59  E-value: 5.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105  386 FSKIRSLKREMRS--------VSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDlKKQEVKQL 457
Cdd:pfam00134  20 MDQQPDINPKMRAilidwlveVHEKFKLLPETLYLAVNYLDRFLSKKSVPKNKLQLVGVTCLFIAAKYEEI-YPPTVEDL 98

                          90       100
                  ....*....|....*....|....*..
gi 189536105  458 IDRLEERFRinRKELISLEFTVLVALE 484
Cdd:pfam00134  99 VYITDNAYT--REEILRMERLILETLN 123
CYCLIN smart00385
domain present in cyclins, TFIIB and Retinoblastoma; A helical domain present in cyclins and ...
 396-445 1.60e-05

domain present in cyclins, TFIIB and Retinoblastoma; A helical domain present in cyclins and TFIIB (twice) and Retinoblastoma (once). A protein recognition domain functioning in cell-cycle and transcription control.


Pssm-ID: 214641 [Multi-domain]  Cd Length: 83  Bit Score: 42.96  E-value: 1.60e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 189536105   396 MRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKI 445
Cdd:smart00385   3 LRRVCKALNLDPETLNLAVNLLDRFLSDYKFLKYSPSLIAAAALYLASKT 52
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-191 1.02e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105    2 AAAACGPRGCPRTNSAKPHKELLRKSRDSRRRQAALLFLTNISLDGRPVYNLSNGLVGPREVDSRCVDVGAAVAGLPLST 81
Cdd:PHA03307  202 ASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSR 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105   82 TSSygtftqVSSSISGGAATPIPRTNVNTYPAPMSPPPALNQGSSDvfTEDGRSDPLSVQAPPlSPTAGPRNTALGSSKS 161
Cdd:PHA03307  282 PGP------ASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSS--RESSSSSTSSSSESS-RGAAVSPGPSPSRSPS 352

                         170       180       190
                  ....*....|....*....|....*....|
gi 189536105  162 PSQFPSSNPLPDPRQRTRNLSGSPGPKVSK 191
Cdd:PHA03307  353 PSRPPPPADPSSPRKRPRPSRAPSSPAASA 382
 
Name Accession Description Interval E-value
CYCLIN_CABLES2 cd20603
cyclin box found in CDK5 and ABL1 enzyme substrate 2 (CABLES2); CABLES2, also called ...
 384-504 1.09e-75

cyclin box found in CDK5 and ABL1 enzyme substrate 2 (CABLES2); CABLES2, also called interactor with CDK3 2 (Ik3-2), acts as a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. CABLES2 contains one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410306  Cd Length: 121  Bit Score: 234.01  E-value: 1.09e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105 384 LTFSKIRSLKREMRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKKQEVKQLIDRLEE 463
Cdd:cd20603    1 LTLSKIRSLKREMRNVAEECNLEPVTVAMAYVYFEKLVLQGKLNKQNRKLCAGACVLLAAKISSDLKKHEVKHLIDKLEE 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 189536105 464 RFRINRKELISLEFTVLVALEMALYLPDSKVMPHYRRLVQQ 504
Cdd:cd20603   81 RFRLNRRELISFEFTVLVALELALYLPENQVLPHYRRLTQQ 121
CYCLIN_CABLES1 cd20602
cyclin box found in CDK5 and ABL1 enzyme substrate 1 (CABLES1); CABLES1, also called ...
 375-503 1.58e-69

cyclin box found in CDK5 and ABL1 enzyme substrate 1 (CABLES1); CABLES1, also called interactor with CDK3 1 (Ik3-1), is a cyclin-dependent kinase binding protein that enhances cyclin-dependent kinase tyrosine phosphorylation by non-receptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. CABLES1 contains one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410305  Cd Length: 132  Bit Score: 218.37  E-value: 1.58e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105 375 FKEKFPHIKLTFSKIRSLKREMRSVS-EECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKKQE 453
Cdd:cd20602    1 FKEKFPHIKLTLSKIRSLKREMRKLAqEECGYEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHE 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 189536105 454 VKQLIDRLEERFRINRKELISLEFTVLVALEMALYLPDSKVMPHYRRLVQ 503
Cdd:cd20602   81 VKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQ 130
CYCLIN_CABLES cd20556
cyclin box found in CDK5 and ABL1 enzyme substrate (CABLES) family; The CABLES family includes ...
 384-501 2.48e-59

cyclin box found in CDK5 and ABL1 enzyme substrate (CABLES) family; The CABLES family includes CABLES1 and CABLES2. CABLES1, also called interactor with CDK3 1 (Ik3-1), is a cyclin-dependent kinase binding protein that enhances cyclin-dependent kinase tyrosine phosphorylation by non-receptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. CABLES2, also called interactor with CDK3 2 (Ik3-2), acts as a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. Both, CABLES1 and CABLES2, contain one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410259  Cd Length: 119  Bit Score: 191.24  E-value: 2.48e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105 384 LTFSKIRSLKREMRSV-SEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKKQEVKQLIDRLE 462
Cdd:cd20556    1 LTLSKLRSLKREMLKIaLKLCGLDVSTVALAYVYFEKLVLKGLVNKSNRKLIAGACLLLAAKFNDDVKKEDLKSLLEEIE 80

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 189536105 463 ERFRINRKELISLEFTVLVALEMALYLPDSKVMPHYRRL 501
Cdd:cd20556   81 DVFRLTRKELIAFEFPVLVALEFSLHVPDEEILPHLQRL 119
CYCLIN_SF cd00043
Cyclin box fold superfamily; The cyclin box is a protein binding domain that functions in ...
 391-476 1.39e-09

Cyclin box fold superfamily; The cyclin box is a protein binding domain that functions in cell-cycle and transcriptional control. It is about 100 amino acids in length, composed of five helices, and is present in cyclins, transcription initiation factor IIB (TFIIB), and retinoblastoma tumour suppressor protein (Rb). Cyclins consist of 8 classes of cell cycle regulators that function as regulatory subunits of cyclin-dependent kinases (CDKs), which are serine/threonine kinases. The catalytic activities of CDKs are modulated not only by their interactions with cyclins but also by CDK inhibitors (CKIs). CDKs, cyclins and CKIs play key roles in transcription, epigenetic regulation, metabolism, stem cell self-renewal, neuronal functions, and spermatogenesis. TFIIB is a transcription factor that binds the TATA box. Members in this superfamily contain one or two copies of the cyclin box.


Pssm-ID: 410207 [Multi-domain]  Cd Length: 82  Bit Score: 54.72  E-value: 1.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105 391 SLKREMRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISsdlkkqEVKQLIDRLEERFRINRK 470
Cdd:cd00043    1 KAVDFIRRLCSKLGLPEEVLELAIELLDRFLSKGLLLGRSPELIAAACLYLACKLE------ELPRTLKEIAKVSGVSEK 74


                 ....*.
gi 189536105 471 ELISLE 476
Cdd:cd00043   75 ELRKAE 80
CYCLIN_CCNM_CCNQ_rpt1 cd20534
first cyclin box found in cyclin-M (CCNM) family; The CCNM family proteins, also called ...
 396-448 2.98e-06

first cyclin box found in cyclin-M (CCNM) family; The CCNM family proteins, also called ancient conserved domain proteins (ACDPs), are evolutionarily conserved Mg2+ transporters. CCNM, also called cyclin-Q (CCNQ), or CDK10-activating cyclin, or cyclin-related protein FAM58A, associates with CDK10 to promote its kinase activity. Members of this family contain two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.


Pssm-ID: 410237 [Multi-domain]  Cd Length: 110  Bit Score: 46.01  E-value: 2.98e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 189536105 396 MRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSD 448
Cdd:cd20534    9 IREAGLKLELSSVTIATACVLYHRFYRELSLEDYDPYLVAMACLYLAGKAEEQ 61
Cyclin_N pfam00134
Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a ...
 386-484 5.28e-06

Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.


Pssm-ID: 459686 [Multi-domain]  Cd Length: 127  Bit Score: 45.59  E-value: 5.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105  386 FSKIRSLKREMRS--------VSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDlKKQEVKQL 457
Cdd:pfam00134  20 MDQQPDINPKMRAilidwlveVHEKFKLLPETLYLAVNYLDRFLSKKSVPKNKLQLVGVTCLFIAAKYEEI-YPPTVEDL 98

                          90       100
                  ....*....|....*....|....*..
gi 189536105  458 IDRLEERFRinRKELISLEFTVLVALE 484
Cdd:pfam00134  99 VYITDNAYT--REEILRMERLILETLN 123
CYCLIN smart00385
domain present in cyclins, TFIIB and Retinoblastoma; A helical domain present in cyclins and ...
 396-445 1.60e-05

domain present in cyclins, TFIIB and Retinoblastoma; A helical domain present in cyclins and TFIIB (twice) and Retinoblastoma (once). A protein recognition domain functioning in cell-cycle and transcription control.


Pssm-ID: 214641 [Multi-domain]  Cd Length: 83  Bit Score: 42.96  E-value: 1.60e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 189536105   396 MRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKI 445
Cdd:smart00385   3 LRRVCKALNLDPETLNLAVNLLDRFLSDYKFLKYSPSLIAAAALYLASKT 52
CYCLIN_CCNK_rpt1 cd20530
first cyclin box found in cyclin-K (CCNK) and similar proteins; CCNK is a novel RNA polymerase ...
 404-483 4.40e-05

first cyclin box found in cyclin-K (CCNK) and similar proteins; CCNK is a novel RNA polymerase II-associated C-type cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity. It is a regulatory subunit of cyclin-dependent kinases that mediates the activation of these target kinases. It plays a role in transcriptional regulation by controlling the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). CCNK contains two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.


Pssm-ID: 410233 [Multi-domain]  Cd Length: 115  Bit Score: 42.99  E-value: 4.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105 404 GLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKK-----QEVKQLIDR--LEERFRINRKELISLE 476
Cdd:cd20530   26 GLPYDTIATGIVYFHRFYMFHSFKDFDRYVTAACCLFLAGKVEETPKKckdiiKTARSLLNDkqFAQFGDDPKEEVMVLE 105


                 ....*..
gi 189536105 477 FTVLVAL 483
Cdd:cd20530  106 RILLQTI 112
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-191 1.02e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105    2 AAAACGPRGCPRTNSAKPHKELLRKSRDSRRRQAALLFLTNISLDGRPVYNLSNGLVGPREVDSRCVDVGAAVAGLPLST 81
Cdd:PHA03307  202 ASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSR 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189536105   82 TSSygtftqVSSSISGGAATPIPRTNVNTYPAPMSPPPALNQGSSDvfTEDGRSDPLSVQAPPlSPTAGPRNTALGSSKS 161
Cdd:PHA03307  282 PGP------ASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSS--RESSSSSTSSSSESS-RGAAVSPGPSPSRSPS 352

                         170       180       190
                  ....*....|....*....|....*....|
gi 189536105  162 PSQFPSSNPLPDPRQRTRNLSGSPGPKVSK 191
Cdd:PHA03307  353 PSRPPPPADPSSPRKRPRPSRAPSSPAASA 382
CYCLIN_AcCycL_rpt1 cd20591
first cyclin box found in Arabidopsis thaliana L-type cyclins (CycL) and similar proteins; ...
 410-464 9.63e-03

first cyclin box found in Arabidopsis thaliana L-type cyclins (CycL) and similar proteins; Cyclin-L1-1 (CycL1), also called arginine-rich cyclin 1 (AtRCY1), or protein MODIFIER OF SNC1 12, is the cognate cyclin for cyclin-dependent kinase G1 (CDKG1). It is involved in regulation of DNA methylation and transcriptional silencing. It is required for synapsis and male meiosis, and for the proper splicing of specific resistance (R) genes. L-type cyclins contain two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.


Pssm-ID: 410294 [Multi-domain]  Cd Length: 128  Bit Score: 36.35  E-value: 9.63e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 189536105 410 IAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKK-QEVKQLIDRLEER 464
Cdd:cd20591   36 MATGQVLFQRFYCKKSFARFNVKRVAASCVWLAAKLEESPRKiRQVLMVFHRMECR 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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