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Conserved domains on  [gi|1808492466|ref|XP_002054675|]
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transcription factor Ouib [Drosophila virilis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 5-76 1.16e-11

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


:

Pssm-ID: 462262  Cd Length: 75  Bit Score: 59.78  E-value: 1.16e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1808492466   5 ICRICAVDTDASKAINLFEKSARQLLRQIKLLTGVFLEVKPNLPEVICKICLNDLDCAINFRKRCLRNQKRW 76
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELL 72
zf-H2C2_2 pfam13465
Zinc-finger double domain;
270-292 1.86e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.86e-04
                          10        20
                  ....*....|....*....|...
gi 1808492466 270 RHERTHTNERPFVCSHCGKAFTN 292
Cdd:pfam13465   4 RHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
211-236 1.53e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.53e-03
                          10        20
                  ....*....|....*....|....*.
gi 1808492466 211 AFDRHLRKHSGIRPFQCEQCSARFLS 236
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 309-333 2.88e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


:

Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.78  E-value: 2.88e-03
                          10        20
                  ....*....|....*....|....*
gi 1808492466 309 FRCDLCERSFSRPTHLKTHYRSNTH 333
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
COG5048 super family cl34881
FOG: Zn-finger [General function prediction only];
175-322 3.00e-03

FOG: Zn-finger [General function prediction only];


The actual alignment was detected with superfamily member COG5048:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.29  E-value: 3.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1808492466 175 LRRQLPKCTASKQPRAKQKLPVFFCDQCGNNvtgKSAFDRHLRKHSGIRPFQC--EQCSARFLSAGELKGHQVMH----- 247
Cdd:COG5048   305 LTRHLRSVNHSGESLKPFSCPYSLCGKLFSR---NDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdl 381

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1808492466 248 TGDRKFPCRY--CDRTYVNYSGRLRHERTHTNERP--FVCSHCGKAFTNSYILKNHNLVHTGERLFRCDLCERSFSRPT 322
Cdd:COG5048   382 KNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 5-76 1.16e-11

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 59.78  E-value: 1.16e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1808492466   5 ICRICAVDTDASKAINLFEKSARQLLRQIKLLTGVFLEVKPNLPEVICKICLNDLDCAINFRKRCLRNQKRW 76
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELL 72
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 5-78 3.93e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 52.90  E-value: 3.93e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1808492466    5 ICRICAVDTDASKAInLFEKSARQLLRQIKLLTGVFLEVKPNLPEVICKICLNDLDCAINFRKRCLRNQKRWTQ 78
Cdd:smart00868   1 VCRLCLSESENLVSI-FDESSEASLAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELLRE 73
zf-H2C2_2 pfam13465
Zinc-finger double domain;
270-292 1.86e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.86e-04
                          10        20
                  ....*....|....*....|...
gi 1808492466 270 RHERTHTNERPFVCSHCGKAFTN 292
Cdd:pfam13465   4 RHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
211-236 1.53e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.53e-03
                          10        20
                  ....*....|....*....|....*.
gi 1808492466 211 AFDRHLRKHSGIRPFQCEQCSARFLS 236
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 309-333 2.88e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.78  E-value: 2.88e-03
                          10        20
                  ....*....|....*....|....*
gi 1808492466 309 FRCDLCERSFSRPTHLKTHYRSNTH 333
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
175-322 3.00e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.29  E-value: 3.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1808492466 175 LRRQLPKCTASKQPRAKQKLPVFFCDQCGNNvtgKSAFDRHLRKHSGIRPFQC--EQCSARFLSAGELKGHQVMH----- 247
Cdd:COG5048   305 LTRHLRSVNHSGESLKPFSCPYSLCGKLFSR---NDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdl 381

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1808492466 248 TGDRKFPCRY--CDRTYVNYSGRLRHERTHTNERP--FVCSHCGKAFTNSYILKNHNLVHTGERLFRCDLCERSFSRPT 322
Cdd:COG5048   382 KNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 5-76 1.16e-11

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 59.78  E-value: 1.16e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1808492466   5 ICRICAVDTDASKAINLFEKSARQLLRQIKLLTGVFLEVKPNLPEVICKICLNDLDCAINFRKRCLRNQKRW 76
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELL 72
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 5-78 3.93e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 52.90  E-value: 3.93e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1808492466    5 ICRICAVDTDASKAInLFEKSARQLLRQIKLLTGVFLEVKPNLPEVICKICLNDLDCAINFRKRCLRNQKRWTQ 78
Cdd:smart00868   1 VCRLCLSESENLVSI-FDESSEASLAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELLRE 73
zf-H2C2_2 pfam13465
Zinc-finger double domain;
270-292 1.86e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.86e-04
                          10        20
                  ....*....|....*....|...
gi 1808492466 270 RHERTHTNERPFVCSHCGKAFTN 292
Cdd:pfam13465   4 RHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
211-236 1.53e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.53e-03
                          10        20
                  ....*....|....*....|....*.
gi 1808492466 211 AFDRHLRKHSGIRPFQCEQCSARFLS 236
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 309-333 2.88e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.78  E-value: 2.88e-03
                          10        20
                  ....*....|....*....|....*
gi 1808492466 309 FRCDLCERSFSRPTHLKTHYRSNTH 333
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
175-322 3.00e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.29  E-value: 3.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1808492466 175 LRRQLPKCTASKQPRAKQKLPVFFCDQCGNNvtgKSAFDRHLRKHSGIRPFQC--EQCSARFLSAGELKGHQVMH----- 247
Cdd:COG5048   305 LTRHLRSVNHSGESLKPFSCPYSLCGKLFSR---NDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdl 381

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1808492466 248 TGDRKFPCRY--CDRTYVNYSGRLRHERTHTNERP--FVCSHCGKAFTNSYILKNHNLVHTGERLFRCDLCERSFSRPT 322
Cdd:COG5048   382 KNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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