|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
4-1076 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 2050.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 4 DGAEKKMSTERRDKLLGIEKIIQKRWEDAKIFEVDASDEPPKPGEKYFGNFPYPYMNGVLHLGHAFSLSKLEFSAAFQRL 83
Cdd:PLN02959 1 MMAEGGKSTARRDRLLEIEVAVQKWWEEEKVFEAEAGDEPPKPGEKFFGNFPYPYMNGLLHLGHAFSLSKLEFAAAYHRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 84 CGTKVLLPMGFHCTGMPIKACADKLVRESEEFGCPPVFPTEVTDEAPAPVANKE----EVPVEVKFKAKKSKAVAKSGAS 159
Cdd:PLN02959 81 RGANVLLPFAFHCTGMPIKASADKLAREIQQYGNPPVFPEEDEDEAAAVAAAKAeaeaAAAPPDKFKGKKSKAVAKSGTQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 160 KYQWTIMRSLGLEDDEIAKFRDPLYWLEYFPPIAKNDLKVFGLSCDWRRSFITTEANPYYDSFVRWQFEHLREKKKVGKD 239
Cdd:PLN02959 161 KYQWEIMRSFGLPDSEIAKFQDPYHWLSYFPPLAKEDLKAFGLGCDWRRSFITTDVNPYYDAFVRWQFRKLKKKGKIVKD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 240 LRYAIYSPLDRQPCADHDRASGEGVAPQEYVLIKMEVQPPFTGKLKALEGKKVFLAAATLRPETMYGQTNAWVLADGDYG 319
Cdd:PLN02959 241 KRYTIYSPLDGQPCADHDRASGEGVGPQEYVLIKMEVLPPFPGKLKALEGKKVFLAAATLRPETMYGQTNCWVLPDGKYG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 320 AYEVSATEVFVVTARAALNMAYQNLSRVPQQPTCLVELKGQDLIGLAVVSPLAKNPVVYVLPMLNIKTDKGTGVVTSVPS 399
Cdd:PLN02959 321 AYEINDTEVFILTARAALNLAYQNFSKVPGKPTCLVELTGYDLIGLPLKSPLAFNEVIYALPMLTILTDKGTGVVTSVPS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 400 DSPDDYMALSDLKSKPALRAKFNVQDEWVLPFEVLPIINVPEFGDKSAEAVCISMKIKSQNNRDDLEAAKKMTYLKGFTD 479
Cdd:PLN02959 401 DSPDDYMALSDLKAKPALRAKYGVKDEWVLPFEVVPIINIPEFGDKSAEKVCEDLKIKSQNDKEKLAEAKRLTYLKGFTD 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 480 GKMLVGDYAGMKVQEAKPLIKKLLVESGQAVIYSEPEKKVISRSGDECVVALTDQWYLQYGEEEWKSQAEKCLTQMELYS 559
Cdd:PLN02959 481 GTMLVGEYAGRKVQEAKPLIKKKLIEAGQAILYSEPEKKVMSRSGDECVVALTDQWYLTYGEEEWKKKAEKCLSKMNLYS 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 560 DETRRLFEHALGWLNQWACSRSFGLGTKFPWDQDFLIESLSDSTIYMAYYTLAHILQEGDLYGKGDHAVKPNQMTRDVWD 639
Cdd:PLN02959 561 DETRHGFEHTLGWLNQWACSRSFGLGTRIPWDEQFLIESLSDSTIYMAYYTVAHLLQGGDMYGKDKSSIKPEQMTDEVWD 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 640 FVFGMGPLPE-SEIPVETLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWPRSFRCNGFLLLNGEKMA 718
Cdd:PLN02959 641 FVFCGGPLPKsSDIPAELLEKMKQEFEYWYPFDLRVSGKDLIQNHLTFAIYNHTAIWAEEHWPRGFRCNGHLMLNSEKMS 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 719 KSTGNFLTIRDAVSDFSADATRFGLADAGDSVDDANFVKLTANSAILRLTKEMAWMsDEVIAAEKDLRKGSPTTFADRVF 798
Cdd:PLN02959 721 KSTGNFLTLRQAIEEFSADATRFALADAGDGVDDANFVFETANAAILRLTKEIAWM-EEVLAAESSLRTGPPSTYADRVF 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 799 ENEINIAINQTERNYKALMFREALKSGFYDLQIARDEYRLACSSSGMNRDLIFRFADVQTRLLTPICPHYAEYVRSEIFH 878
Cdd:PLN02959 800 ENEINIAIAETEKNYEAMMFREALKSGFYDLQAARDEYRLSCGSGGMNRDLVWRFMDVQTRLITPICPHYAEHVWREILK 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 879 QEGFAVTAGWPASGTPDLTLQRANKFFQSILADFRKALQKHLAASKKAKKGQA-AVPPAAPLAGLIYVAEKYEGWKEESL 957
Cdd:PLN02959 880 KEGFAVTAGWPVAGEPDLTLKRANKYLQDSIVSFRKLLQKQLAGSKKAKKGGApVTLPEKKLAGLIYVAEKYDGWKEECL 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 958 KILQSCYDSGSKTFTSDVEILSRLRESSVGQSGDFKQIQKKCMPFVKFKKDETLSVGPQALELRLPFDERWVFEENLELI 1037
Cdd:PLN02959 960 RILQSKFDSQSRTFAPDAEILEALKESSVGQEANFKQVQKLCMPFVKFKKDEAIAVGPQALDLKLPFDEIEVLQENLELI 1039
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*
gi 302755993 1038 KAQLGLESMMVVPVSSSSSGKIAAAAQAA------SPGSPVIVFV 1076
Cdd:PLN02959 1040 KRQLGLEEVEILSASDPDAVAKAGAHASLlkqnppSPGNPVAIFV 1084
|
|
| leuS_arch |
TIGR00395 |
leucyl-tRNA synthetase, archaeal and cytosolic family; The leucyl-tRNA synthetases belong to ... |
21-1075 |
0e+00 |
|
leucyl-tRNA synthetase, archaeal and cytosolic family; The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both archaeal and cytosolic eukaryotic leucyl-tRNA synthetases; the eubacterial and mitochondrial forms differ so substantially that some other tRNA ligases score higher by this model than does any eubacterial LeuS. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273056 [Multi-domain] Cd Length: 938 Bit Score: 817.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 21 IEKIIQKRWEDAKIFEVDASDEppkpgEKYFGNFPYPYMNGVLHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHCTGMP 100
Cdd:TIGR00395 3 IEKKWQKRWEEAHIFEADPDDR-----EKFFLTMAYPYLNGVMHAGHCRTFTIPEVSARFERMKGKNVLFPLGFHVTGTP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 101 IKACADKLVRESEEFGcppvfptEVTDEAPApvankeeVPVEvkfkakkskavaksgaskyqwtimrslgleddEIAKFR 180
Cdd:TIGR00395 78 ILGLAELIKRRDELTI-------KNYTEVHA-------IPRE--------------------------------ELLKFT 111
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 181 DPLYWLEYFPPIAKNDLKVFGLSCDWRRSFITTEanPYYDSFVRWQFEHLREKKKVGKDLRYAIYSPLDRQPCADHDRAS 260
Cdd:TIGR00395 112 DPEYIVEYFSREAESACKSMGYSIDWRRSFKTTD--PYYDRFIEWQMNKLKELGLIVKGEHPVRYCPKDGNPVEDHDLLS 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 261 GEGVAPQEYVLIKMEvqppftgklkaLEGKKVFLAAATLRPETMYGQTNAWVLADGDYGAYEVSAtEVFVVTARAALNMA 340
Cdd:TIGR00395 190 GEGVTIVEYILIKFE-----------LEDGAFYFVAATLRPETVYGVTNCWVNPTITYVIAEVGG-EKWITSKEAFENLS 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 341 YQNLSRVPqqptcLVELKGQDLIGLAVVSPLAkNPVVYVLPMLNIKTDKGTGVVTSVPSDSPDDYMALSDLKSKPALRAK 420
Cdd:TIGR00395 258 YQKLKYKP-----IEEVPGKQFIGKKVHNPVV-GPEVPILPAEFVDTTKGTGVVMSVPAHAPDDYIALEDLLHDPEYLGI 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 421 FNVQDEwvlpFEVLPIINVPEFGDKSAEAVCISMKIKSQNNRDDLEAAKKMTYLKGFTDGKMLVG--DYAGMKVQEAKPL 498
Cdd:TIGR00395 332 KPVVID----IEPVPLIHTDGYGDLPAKEIVEEKGIKSQKDKNLLEEATKILYKEEYHTGVMIYNipPYKGMKVSEAKEK 407
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 499 IKKLLVESGQAVIYSEP-EKKVISRSGDECVV-ALTDQWYLQYGEEEWKSQAEKCLTQMELYSDETRRLFEHALGWLNQW 576
Cdd:TIGR00395 408 VKADLIDAGLADVMYEFsESPVICRCGTDCIVkVVEDQWFVKYSDESWKELAHECLEGMRIIPEEVKNAFEGKIDWLKDW 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 577 ACSRSFGLGTKFPWDQDFLIESLSDSTIYMAYYTLAHILQEGDLygkgdhavKPNQMTRDVWDFVF-GMGPLPESEIPVE 655
Cdd:TIGR00395 488 ACCRRYGLGTRLPWDEKWLIESLSDSTIYMAYYTIAHYLNKDYY--------GNEQMTDEFFDYIFlGKGDVKNTNIPLP 559
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 656 TLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFS 735
Cdd:TIGR00395 560 AIQKLRREFEYWYPLDWRISGKDLIPNHLTFYIFHHVAIFPEKFWPRGIVVNGYVMLEGKKMSKSKGNVLTLEQAVEKFG 639
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 736 ADATRFGLADAGDSVDDANFVKLTANSAILRLTKEMAWMsdEVIAAEKDLRKGSPTTFADRVFENEINIAINQTERNYKA 815
Cdd:TIGR00395 640 ADVARLYIADAAETVQDADWKESEVEGTILRLERLYEFA--EEITKESNLETGEETSFIDRWLESRMNAAIKETYEAMEN 717
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 816 LMFREALKSGFYDLQIARDEYRLAcsSSGMNRDLIFRFADVQTRLLTPICPHYAEYVRSEIFHqEGFAVTAGWPASGTP- 894
Cdd:TIGR00395 718 FQTRKAVKYALFDLQADVDWYRRR--GGVNHKDVLARYLETWIKLLAPFAPHFAEEMWEEVGN-EGFVSLAKFPEASEPa 794
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 895 -DLTLQRANKFFQSILADFRKAlqKHLAASKKAKKgqaavppaaplagLIYVAEKyegWKEESLKILQscyDSGSKTFTS 973
Cdd:TIGR00395 795 vDKEVEAAEEYLRNLVRDIQEI--AKIDASKPKRV-------------YLYTSED---WKSQCLKIVA---ELFGEDTGE 853
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 974 DVEILSRLREssvgqsgdfkqIQKKCMPFVKFKKDETLSVGPQALELrlpFDERWVFEENLELIKAQLGLESMMVVPVSS 1053
Cdd:TIGR00395 854 DMKKVMEEPE-----------ERKRGKEVISLVKQIIKDEKKEDELQ---ISEIEVLKAAARFIKKEVGALVIIEFSADS 919
|
1050 1060
....*....|....*....|..
gi 302755993 1054 SSSGKiaaaAQAASPGSPVIVF 1075
Cdd:TIGR00395 920 FPENK----KRNAVPGKPAIYL 937
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
63-1044 |
0e+00 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 731.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 63 LHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHCTGMPIKACADKlvreseefgcppvfptevtdeapapVANKEEvpve 142
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFPMAFHVTGTPILGIAER-------------------------IARGDP---- 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 143 vkfkakkskavaksgasKYQWTIMRSLGLEDDEIAKFRDPLYWLEYFPPIAKNDLKVFGLSCDWRRSFITTEanPYYDSF 222
Cdd:PRK12300 52 -----------------ETIELYKSLYGIPEEELEKFKDPEYIVEYFSEEAKEDMKRIGYSIDWRREFTTTD--PEYSKF 112
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 223 VRWQFEHLREKKKVGKDLRYAIYSPLDRQPCADHDRASGEGVAPQEYVLIKmevqppFTgklkalEGKKVFLAAATLRPE 302
Cdd:PRK12300 113 IEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVGDHDLLDGEEPEIVEYTLIK------FE------ESEDLILPAATLRPE 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 303 TMYGQTNAWVLADGDYGAYEVSAtEVFVVTARAALNMAYQNLS-RVpqqptcLVELKGQDLIGLAVVSPLAKNPVVyVLP 381
Cdd:PRK12300 181 TIFGVTNLWVNPDATYVKAEVDG-EKWIVSKEAAEKLSFQDRDvEI------IEEIKGSELIGKKVKNPVTGKEVP-ILP 252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 382 MLNIKTDKGTGVVTSVPSDSPDDYMALSDLKSKPALRAKFnvqdewvlpfEVLPIINVPEFGDKSAEAVCISMKIKSQNN 461
Cdd:PRK12300 253 ADFVDPDNGTGVVMSVPAHAPYDYVALRDLKKNKELLDVI----------EPIPLIEVEGYGEFPAKEVVEKLGIKSQED 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 462 RDdLEAAKKMTYLKGFTDGKML--VGDYAGMKVQEAKPLIKKLLVESGQA-VIYSEPEKKVISRSGDECVVA-LTDQWYL 537
Cdd:PRK12300 323 PE-LEEATKEVYRAEFHKGVLKenTGEYAGKPVREAREKITKDLIEKGIAdIMYEFSNRPVYCRCGTECVVKvVKDQWFI 401
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 538 QYGEEEWKSQAEKCLTQMELYSDETRRLFEHALGWLNQWACSRSFGLGTKFPWDQDFLIESLSDSTIYMAYYTLAHILQE 617
Cdd:PRK12300 402 DYSDPEWKELAHKALDNMEIIPEEYRKEFENTIDWLKDRACARRRGLGTRLPWDEEWIIESLSDSTIYMAYYTIAHKIRE 481
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 618 GDLygkgdhavKPNQMTRDVWDFVF-GMGPLPE----SEIPVETLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHT 692
Cdd:PRK12300 482 YGI--------KPEQLTPEFFDYVFlGKGDPEEvskkTGIPKEILEEMREEFLYWYPVDWRHSGKDLIPNHLTFFIFNHV 553
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 693 AMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDSVDDANFVKLTANSAILRLTK--E 770
Cdd:PRK12300 554 AIFPEEKWPRGIVVNGFVLLEGKKMSKSKGNVIPLRKAIEEYGADVVRLYLTSSAELLQDADWREKEVESVRRQLERfyE 633
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 771 MAwmsDEVIAAEKDlrkgSPTTFADRVFENEINIAINQTERNYKALMFREALKSGFYDLQIARDEYRLacSSSGMNRDLI 850
Cdd:PRK12300 634 LA---KELIEIGGE----EELRFIDKWLLSRLNRIIKETTEAMESFQTRDAVQEAFYELLNDLRWYLR--RVGEANNKVL 704
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 851 FRFADVQTRLLTPICPHYAEyvrsEIFHQ---EGFAVTAGWPASG--TPDLTLQRANKFFQSILADFRKALQkhlAASKK 925
Cdd:PRK12300 705 REVLEIWIRLLAPFTPHLAE----ELWHKlggEGFVSLEKWPEPDesKIDEEAELAEEYVKRLIEDIREILK---VAKIK 777
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 926 AKKgqaavppaaplaGLIYVAEKyegWKEESLKILQSCYDSGS--KTFTSDVEILSRLRESSvgqsgdfkQIQKKCMPFV 1003
Cdd:PRK12300 778 PKK------------VYIYVAPD---WKYEVLEIAAENGDVKEaiKELMKDEELRKHGKEVA--------KLAQKIVKEV 834
|
970 980 990 1000
....*....|....*....|....*....|....*....|.
gi 302755993 1004 KFKKDETLSVgpqaleLRLPFDERWVFEENLELIKAQLGLE 1044
Cdd:PRK12300 835 LKLDKEVRKL------ILKNIDEEEVLEEAKDFLEKELGVE 869
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
530-756 |
2.93e-68 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 231.75 E-value: 2.93e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 530 ALTDQWYLQYGEEEWKSQAEKCLTQMELYSDETRRLFEHALGwlnqwaCSRSFGLGTKFPWDqdFLIESLSDSTIYMAYY 609
Cdd:cd00812 127 KLLDQWFLKYSETEWKEKLLKDLEKLDGWPEEVRAMQENWIG------CSRQRYWGTPIPWT--DTMESLSDSTWYYARY 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 610 TLAHILQEGDLYgkgdhavkpnqmtrdvwdfvfgmgplpeseipveTLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIY 689
Cdd:cd00812 199 TDAHNLEQPYEG----------------------------------DLEFDREEFEYWYPVDIYIGGKEHAPNHLLYSRF 244
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 302755993 690 NHTAMFPEER----WPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDsvDDANFV 756
Cdd:cd00812 245 NHKALFDEGLvtdePPKGLIVQGMVLLEGEKMSKSKGNVVTPDEAIKKYGADAARLYILFAAP--PDADFD 313
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
755-876 |
1.49e-36 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 133.87 E-value: 1.49e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 755 FVKLTANSAILRLTKEMAWMSdEVIAAEKDLrkgSPTTFADRVFENEINIAINQTERNYKALMFREALKSGFYDLQIARD 834
Cdd:cd07959 1 FREEEANSAILRLERFYELAE-ELIETEGEL---EELTFIDRWLLSRLNRLIKETTEAYENMQFREALKEGLYELQNDLD 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 302755993 835 EYRLACsSSGMNRDLIFRFADVQTRLLTPICPHYAEYVRSEI 876
Cdd:cd07959 77 WYRERG-GAGMNKDLLRRFIEVWTRLLAPFAPHLAEEIWHEL 117
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
25-755 |
4.74e-32 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 133.30 E-value: 4.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 25 IQKRWEDAKIFEvdASDEPPKPGEKYFGNFPYPYMNGVLHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHCTGMPIKAC 104
Cdd:pfam00133 2 IYEFWDEQGYFK--PELEKRKGKPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEQV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 105 ADKLVRESEEfgcppvfptevtdeapapvankeevpvevkfkakkskavaksgaskyqwTIMRSLGLEddeiaKFRDPLY 184
Cdd:pfam00133 80 VEKKLGIKEK-------------------------------------------------KTRHKYGRE-----EFREKCR 105
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 185 -WLEYFPPIAKNDLKVFGLSCDWRRSFITTEanPYYDSFVRWQFEHLREKKKVGKDLRYAIYSPLDRQPCADhdrasgeg 263
Cdd:pfam00133 106 eWKMEYADEIRKQFRRLGRSIDWDREYFTMD--PELEAAVWEVFVRLHDKGLIYRGKKLVNWSPALNTALSN-------- 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 264 vAPQEYvlikMEVQPPFTG-KLKALEGKKVFLAAATLRPETMYGQTNAWVLADGDYGAyevsaTEVFVVTARAALNMAYQ 342
Cdd:pfam00133 176 -LEVEY----KDVKGPSIHvAFPLADDEGASLVIWTTTPWTLPGNTAVAVNPEFDYVI-----TGEGYILAEALLKSLYK 245
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 343 NLSrvpqQPTCLVELKGQDLIGLAVVSPLA--KNPVV---YVlpmlniKTDKGTGVVTSVPSDSPDDYmalsdlkskpAL 417
Cdd:pfam00133 246 KGT----DKKILEDFRGKELEGKEAIHPFVnrEIPIItddYV------DMEFGTGAVHIAPAHGENDY----------EV 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 418 RAKFNvqdewvlpfevLPIINVpefgdksaeavcismkiksqnnrddleaakkMTYLKGFTDGkmlVGDYAGMKVQEAKP 497
Cdd:pfam00133 306 GQRHN-----------LEVINP-------------------------------VDDDGTFTEE---APDFQGVYRFDARK 340
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 498 LIKKLLVESGqAVIYSEPEKKVI---SRSGDECVVALTDQWYLQYgeEEWKSQAEKCLTQMELYSDETRRLFEHALGWLN 574
Cdd:pfam00133 341 KIVELLTEKG-LLLKIEPFTHSYpfcWRSGTPIIPRATPQWFVRM--DELADQALEAVEKVQFVPKSGEKRYFNWLANIQ 417
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 575 QWACSRSFGLGTKFP-W-DQDFLIESLSDSTIYMAyytlAHILQE-----------GDLYGKGDHAVKPNQMTRDVWdFV 641
Cdd:pfam00133 418 DWCISRQRWWGHPIPaWvSKDTEEVVCRGELFELV----AGRFEEegsikwlhreaKDKLGYGKGTLEQDEDVLDTW-FS 492
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 642 FGMGPLPESEIPVETlkrmKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWpRSFRCNGFLL-LNGEKMAKS 720
Cdd:pfam00133 493 SGSWPFSTLGWPFVN----TEEFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGSVPF-KNVLVHGLVRdEQGRKMSKS 567
|
730 740 750
....*....|....*....|....*....|....*
gi 302755993 721 TGNFLTIRDAVSDFSADATRFGLADAgDSVDDANF 755
Cdd:pfam00133 568 LGNVIDPLDVIDKYGADALRLWLANS-DYGRDINL 601
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
49-239 |
1.72e-29 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 120.05 E-value: 1.72e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 49 KYFGNFPYPYMNGVLHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHCTGMPIKACADKLVreseefgcppvfptevtde 128
Cdd:cd00812 1 KFYILVMFPYPSGALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFDAFGLPAENAAIKIG------------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 129 apapvankeevpvevkfkakkskavaksgaskyqwtimrslgleddeiakfRDPLYWLEYFPPIAKNDLKVFGLSCDWRR 208
Cdd:cd00812 62 ---------------------------------------------------RDPEDWTEYNIKKMKEQLKRMGFSYDWRR 90
|
170 180 190
....*....|....*....|....*....|.
gi 302755993 209 SFITTeaNPYYDSFVRWQFEHLREKKKVGKD 239
Cdd:cd00812 91 EFTTC--DPEYYKFTQWLFLKLYEKGLAYKK 119
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
21-910 |
2.28e-26 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 116.70 E-value: 2.28e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 21 IEKIIQKRWEDAKIFEVDASdeppKPGEKYFGNFPYPYMNGVLHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHCTGMP 100
Cdd:TIGR00422 10 VEKKWYKKWEKSGFFKPDGN----SNKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGTDHAGIA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 101 IKACADKLVREseefgcppvfptevtdeapapvankeevpvevkfkakkskavakSGASKYQwtimrsLGLEddeiaKFR 180
Cdd:TIGR00422 86 TQVKVEKKLGA--------------------------------------------EGKTKHD------LGRE-----EFR 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 181 DPLY-WLEYFPPIAKNDLKVFGLSCDWRRSFITTEANPYY---DSFVRWQFehlrekkkvgKDLRYAIYSPLDRQPcadh 256
Cdd:TIGR00422 111 EKIWeWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKavkEAFVRLYE----------KGLIYRGEYLVNWDP---- 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 257 drASGEGVAPQEyvLIKMEVQppftGKL-----KALEGKKVFLAAATLRPETMYGQTNAWVLADGDygayevsatevfvv 331
Cdd:TIGR00422 177 --KLNTAISDIE--VEYKEVK----GKLyyiryPLANGSKDYLVVATTRPETMFGDTAVAVHPEDE-------------- 234
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 332 taraalnmayqnlsrvpqqptclvelKGQDLIGLAVVSPL--AKNPVV---YVLPmlniktDKGTGVVTSVPSDSPDDYm 406
Cdd:TIGR00422 235 --------------------------RYKHLIGKKVILPLtgRKIPIIadeYVDM------EFGTGAVKVTPAHDFNDY- 281
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 407 alsdlkskpalrakfnvqdEWvlpfevlpiinvpefgdksaeavcismkiksqNNRDDLEAAKKMTYlkgftDGKM--LV 484
Cdd:TIGR00422 282 -------------------EW--------------------------------GKRHNLEFINILDE-----DGLLneNA 305
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 485 GDYAGMKVQEAKPLI------KKLLVES---GQAVIYSEpekkvisRSGDECVVALTDQWYLQYgeEEWKSQAEKCL--T 553
Cdd:TIGR00422 306 GKYQGLTRFEARKKIvedlkeEGLLVKIephTHNVGTCW-------RSGTVVEPLLSKQWFVKV--EKLADKALEAAeeG 376
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 554 QMELYSDETRRLFEHALGWLNQWACSRSFGLGTKFPwdqdflieslsdstiymAYYtlahILQEGDLY--GKGDHAVKPN 631
Cdd:TIGR00422 377 EIKFVPKRMEKRYLNWLRNIKDWCISRQLIWGHRIP-----------------VWY----CKECGEVYvaKEEPLPDDKT 435
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 632 QMTR--------DVWDFVFGMGPLPESeipveTLK--RMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWP 701
Cdd:TIGR00422 436 NTGPsveleqdtDVLDTWFSSSLWPFS-----TLGwpDETKDLKKFYPTDLLVTGYDIIFFWVARMIFRSLALTGQVPFK 510
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 702 RSFrCNGFLL-LNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDSVDDANF----VKLTANSA---------ILRL 767
Cdd:TIGR00422 511 EVY-IHGLVRdEQGRKMSKSLGNVIDPLDVIEKYGADALRFTLASLVTPGDDINFdwkrVESARNFLnklwnasrfVLMN 589
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 768 TKEMawmsdeviaaeKDLRKGS-PTTFADRVFENEINIAINQTER---NYKalmFREALKS-------GFYDLQIARDEY 836
Cdd:TIGR00422 590 LSDD-----------LELSGGEeKLSLADRWILSKLNRTIKEVRKaldKYR---FAEAAKAlyefiwnDFCDWYIELVKY 655
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 302755993 837 RLACSSSGMNRDLIFRFA---DVQTRLLTPICPHYAEYVRSEIFHQEGFAVTAGWPASgTPDLTLQRANKFFQSILA 910
Cdd:TIGR00422 656 RLYNGNEAEKKAARDTLYyvlDKALRLLHPFMPFITEEIWQHFKEGADSIMLQSYPVV-DAEFVDEEAEKAFELLKE 731
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
516-741 |
1.44e-24 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 105.58 E-value: 1.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 516 EKKVISRsgDECVVALTDQWYLQYgeEEWKSQAEKCLTQMELYSDETRRLFEHALGWLNQWACSRSFGLGTKFPWDqdfL 595
Cdd:cd00668 125 EKGLIYR--GTHPVRITEQWFFDM--PKFKEKLLKALRRGKIVPEHVKNRMEAWLESLLDWAISRQRYWGTPLPED---V 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 596 IESLSDSTIYMAYYTlahilqegdlygkgdhavkpnqmtrdvwdfvfgmGPLPEseipvetlkrmKKEFDYWYPFDLRVS 675
Cdd:cd00668 198 FDVWFDSGIGPLGSL----------------------------------GYPEE-----------KEWFKDSYPADWHLI 232
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 302755993 676 GKDLIQNHLTFSIYNHTAMFpEERWPRSFRCNGFLLLN-GEKMAKSTGNFLTIRDAVSDFSADATRF 741
Cdd:cd00668 233 GKDILRGWANFWITMLVALF-GEIPPKNLLVHGFVLDEgGQKMSKSKGNVIDPSDVVEKYGADALRY 298
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
20-889 |
9.40e-14 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 76.00 E-value: 9.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 20 GIEKIIQKRWEDAKIFEVDAS--------DEPPkpgekyfgnfpyPYMNGVLHLGHAFSLSKLEFSAAFQRLCGTKVLLP 91
Cdd:PRK13208 14 ELEEKWQKIWEEEGTYKFDPDerkpvysiDTPP------------PTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFFP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 92 MGFHCTGMPIKacadklVRESEEFGcppvfpteVTdeapapvanKEEVPVEvkfkakkskavaksgasKY-----QWTim 166
Cdd:PRK13208 82 QGWDDNGLPTE------RKVEKYYG--------IR---------KDDISRE-----------------EFielcrELT-- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 167 rslgleDDEIAKFRdplywleyfppiakNDLKVFGLSCDWRRSFITTEanPYY-----DSFVRwqfehLREKKKVGKDLR 241
Cdd:PRK13208 120 ------DEDEKKFR--------------ELWRRLGLSVDWSLEYQTIS--PEYrrisqKSFLD-----LYKKGLIYRAEA 172
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 242 YAIYSPLDRQPCADhdrasgegvAPQEYVlikmevqpPFTGKL-----KALEGKKVFLaaATLRPETMyGQTNAwVLA-- 314
Cdd:PRK13208 173 PVLWCPRCETAIAQ---------AEVEYR--------EREGKLnyikfPVEDGEEIEI--ATTRPELL-PACVA-VVVhp 231
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 315 -DGDYgayevsatevfvvtaraalnmayqnlsrvpqqptclvelkgQDLIGLAVVSPLAKNPVVyVLPMLNIKTDKGTGV 393
Cdd:PRK13208 232 dDERY-----------------------------------------KHLVGKTAIVPLFGVEVP-ILADPLVDPDFGTGA 269
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 394 VtsvpsdspddyMALS--DLkskpalrakfnvQD-EWV----LPfeVLPIInvpefgDKsaeavcismkiksqnnrddle 466
Cdd:PRK13208 270 V-----------MICTfgDK------------TDvTWWrelnLP--TRIII------DE--------------------- 297
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 467 aakkmtylkgftDGKML--VGDYAGMKVQEAKPLIKKLLvESGQAVIysEPEK-----KVISRSGD--ECVValTDQWYL 537
Cdd:PRK13208 298 ------------DGRMTeaAGKLAGLTIEEARKKIVEDL-KSGGLLG--KQEPikhnvKFCERCDTplEILV--TRQWFI 360
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 538 QYgeEEWKSQAEKCLTQMELYSDETRRLFEHalgWLNQ----WACSRSFGLGTKFP-WdqdfliESLSDSTIYMAyytla 612
Cdd:PRK13208 361 KV--LDLKEELLERGKEINWYPEHMRVRLEN---WIEGlnwdWCISRQRYFGTPIPvW------YCKDCGHPILP----- 424
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 613 hilQEGDL-----------YGK---GDHAVKPNQMTRDVW-DfvfgmgplpeSEIPVETLKRMKKEFDYW---YPFDLRV 674
Cdd:PRK13208 425 ---DEEDLpvdptkdeppgYKCpqcGSPGFEGETDVMDTWaT----------SSITPLIVTGWERDEDLFekvFPMDLRP 491
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 675 SGKDLIQNHLTFSI---YNHTAMFPeerWpRSFRCNGFLL-LNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADA--G- 747
Cdd:PRK13208 492 QGHDIIRTWLFYTIlraYLLTGKLP---W-KNIMISGMVLdPDGKKMSKSKGNVVTPEELLEKYGADAVRYWAASArlGs 567
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 748 DSVDDANFVK---------LTANSAILRLTKEMAWMSDEViaaekdlrkgspTTFADRVFENEINIAINQTERNYKALMF 818
Cdd:PRK13208 568 DTPFDEKQVKigrrlltklWNASRFVLHFSADPEPDKAEV------------LEPLDRWILAKLAKVVEKATEALENYDF 635
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 819 REALKS-------GFYD--LQIARdeYRLACSSSGMNRD-----LifRFA-DVQTRLLTPICPHYAEYVRSEIFhqEGFA 883
Cdd:PRK13208 636 AKALEEiesffwhVFCDdyLELVK--SRAYGEDEEEEQKsarytL--YTVlDTLLRLLAPFLPFITEEVWSWLY--GGSV 709
|
....*.
gi 302755993 884 VTAGWP 889
Cdd:PRK13208 710 HRASWP 715
|
|
| CysRS_core |
cd00672 |
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) ... |
670-743 |
1.52e-11 |
|
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173899 [Multi-domain] Cd Length: 213 Bit Score: 64.91 E-value: 1.52e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 302755993 670 FDLRVSGKDLIQNHLTFSIYNHTAMFPEeRWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGL 743
Cdd:cd00672 129 FDIHGGGVDLIFPHHENEIAQSEAATGK-PFARYWLHTGHLTIDGEKMSKSLGNFITVRDALKKYDPEVLRLAL 201
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
795-928 |
9.68e-10 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 57.80 E-value: 9.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 795 DRVFENEINIAINQTERNYKALMFREALKSGFYDLQIAR-DEY------RLACSSSGMN-RDLIFRFADVQTRLLTPICP 866
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLsDWYlelikdRLYGEEPDSRaQTTLYEVLETLLRLLAPFMP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 302755993 867 HYAEYVrseifHQEGFAVTAGWPA-SGTPDLTLQRANKFFQSILADFRKA-LQKHLAASKKAKK 928
Cdd:pfam08264 81 FITEEL-----WQKESIHLAPWPEdAELEEAELEEAFELRQEIVQAIRKLrSELKIKKSLPLEV 139
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
707-741 |
1.01e-09 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 62.04 E-value: 1.01e-09
10 20 30
....*....|....*....|....*....|....*
gi 302755993 707 NGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRF 741
Cdd:COG0215 256 NGFLTVNGEKMSKSLGNFFTVRDLLKKYDPEVLRF 290
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
519-755 |
1.47e-09 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 61.11 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 519 VISRSGDECVVALTDQWYLQYGEEewKSQAEKCLTQ--MELYSDETRRLFEHalgWLNQ---WACSRSFGLGTKFP-Wdq 592
Cdd:cd00817 155 VCSRSGDVIEPLLKPQWFVKVKDL--AKKALEAVKEgdIKFVPERMEKRYEN---WLENirdWCISRQLWWGHRIPaW-- 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 593 dfliESLSDSTIYMA---YYTLAHILQEGDLYGKGDhAVKPNQMTRDVWdFVFGMGPLPESEIPVETlkrmkKEFDYWYP 669
Cdd:cd00817 228 ----YCKDGGHWVVAreeDEAIDKAAPEACVPCGGE-ELKQDEDVLDTW-FSSSLWPFSTLGWPEET-----KDLKKFYP 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 670 FDLRVSGKDLIQNHLTFSI---YNHTAMFPeerWPRSFrCNGFLL-LNGEKMAKSTGNFLTIRDAVSDFSADATRFGLAD 745
Cdd:cd00817 297 TSLLVTGHDIIFFWVARMImrgLKLTGKLP---FKEVY-LHGLVRdEDGRKMSKSLGNVIDPLDVIDGYGADALRFTLAS 372
|
250
....*....|
gi 302755993 746 AGDSVDDANF 755
Cdd:cd00817 373 AATQGRDINL 382
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
676-823 |
1.84e-09 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 61.67 E-value: 1.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 676 GKDlIqnhltfsIYNHTAMFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDS 749
Cdd:COG0143 289 GKD-I-------IRFHAIIWPamlmaaGLPLPKKVFAHGFLTVEGEKMSKSRGNVIDPDDLLDRYGPDALRYYLLREVPF 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 750 VDDANFvklTANSAILRLTKEMA-----WMS----------DEVIAAEKDLrkgsptTFADRVFENEINIAINQTERNYK 814
Cdd:COG0143 361 GQDGDF---SWEDFVARVNSDLAndlgnLASrtlsmihkyfDGKVPEPGEL------TEADEELLAEAEAALEEVAEAME 431
|
....*....
gi 302755993 815 ALMFREALK 823
Cdd:COG0143 432 AFEFRKALE 440
|
|
| tRNA-synt_1e |
pfam01406 |
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA ... |
668-746 |
1.98e-09 |
|
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA synthetases.
Pssm-ID: 396128 [Multi-domain] Cd Length: 301 Bit Score: 60.07 E-value: 1.98e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 302755993 668 YPFDLRVSGKDLIQNHLTFSIYNHTAMFPEErWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADA 746
Cdd:pfam01406 206 DQIDIHGGGIDLAFPHHENEIAQSEAAFDKQ-LANYWLHNGHVMIDGEKMSKSLGNFFTIRDVLKRYDPEILRYFLLSV 283
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
661-755 |
3.61e-08 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 56.91 E-value: 3.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 661 KKEFDYWYPFDLRVS-----GKDLIqnhltfsiYNHTAMFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRD 729
Cdd:pfam09334 266 EEKWKEWWPNDPDTElvhfiGKDII--------YFHTIFWPamllgaGYRLPTTVFAHGYLTYEGGKMSKSRGNVVWPSE 337
|
90 100
....*....|....*....|....*.
gi 302755993 730 AVSDFSADATRFGLADAGDSVDDANF 755
Cdd:pfam09334 338 ALDRFPPDALRYYLARNRPETKDTDF 363
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
22-406 |
2.81e-07 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 54.78 E-value: 2.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 22 EKIIQKRWEDAKIFE--VDASDeppkpGEKYFGNFPYPYMNGVLHLGHAfsLSKL--EFSAAFQRLCGTKVLLPMGFHCT 97
Cdd:PLN02843 9 EPEIQKLWEENQVYKrvSDRNN-----GESFTLHDGPPYANGDLHIGHA--LNKIlkDFINRYQLLQGKKVHYVPGWDCH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 98 GMPIKacadklvreseefgcppvfpTEVTDEAPAPvANKEEVPVEVKFKakkskavaksgASKYqwtimrSLGLEDDEIA 177
Cdd:PLN02843 82 GLPIE--------------------LKVLQSLDQE-ARKELTPIKLRAK-----------AAKF------AKKTVDTQRE 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 178 KFrdplywleyfppiakndlKVFGLSCDWRRSFITTEanPYYDSFvrwQFE---------HL-REKKKVGkdlryaiYSP 247
Cdd:PLN02843 124 SF------------------KRYGVWGDWENPYLTLD--PEYEAA---QIEvfgqmflngYIyRGRKPVH-------WSP 173
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 248 LDRQPCADHDRASGEG-VAPQEYVLIKMEVQPPFTGKLKALEGKKVFLAAATLRPETMYGQTNAWVLADGDYGAYEVSAT 326
Cdd:PLN02843 174 SSRTALAEAELEYPEGhVSKSIYVAFPVVSPSETSPEELEEFLPGLSLAIWTTTPWTMPANAAVAVNDKLQYSVVEVQSF 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 327 EVFVVTARAALNMAYQNLSRVPQQPTCLV--------------------ELKGQDLIGLAVVSPL--AKNPVV----Yvl 380
Cdd:PLN02843 254 SEDESTSGGNKKKRPGNVLKEQQKLFLIVatdlvpaleakwgvklvvlkTFPGSDLEGCRYIHPLynRESPVViggdY-- 331
|
410 420
....*....|....*....|....*.
gi 302755993 381 pmlnIKTDKGTGVVTSVPSDSPDDYM 406
Cdd:PLN02843 332 ----ITTESGTGLVHTAPGHGQEDYI 353
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
55-100 |
8.92e-07 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 52.63 E-value: 8.92e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 302755993 55 PYPYMNGVLHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHCTGMP 100
Cdd:cd00817 8 PPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIA 53
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
676-755 |
1.07e-06 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 52.85 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 676 GKDLIqnhltfsiYNHTAMFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLA-DAGD 748
Cdd:PRK00133 291 GKDII--------YFHTLFWPamlegaGYRLPTNVFAHGFLTVEGAKMSKSRGTFIWARTYLDHLDPDYLRYYLAaKLPE 362
|
....*..
gi 302755993 749 SVDDANF 755
Cdd:PRK00133 363 TIDDLDF 369
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
663-744 |
6.47e-06 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 50.27 E-value: 6.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 663 EFDYWYPFDLRVSGKDLIQNHltfSIYnhtamFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSA 736
Cdd:PRK11893 248 LFNKYWPADVHLIGKDILRFH---AVY-----WPaflmaaGLPLPKRVFAHGFLTLDGEKMSKSLGNVIDPFDLVDEYGV 319
|
....*...
gi 302755993 737 DATRFGLA 744
Cdd:PRK11893 320 DAVRYFLL 327
|
|
| PTZ00399 |
PTZ00399 |
cysteinyl-tRNA-synthetase; Provisional |
668-741 |
1.12e-05 |
|
cysteinyl-tRNA-synthetase; Provisional
Pssm-ID: 240402 [Multi-domain] Cd Length: 651 Bit Score: 49.64 E-value: 1.12e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 302755993 668 YPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRF 741
Cdd:PTZ00399 267 DPIDIHSGGIDLKFPHHDNELAQSEAYFDKHQWVNYFLHSGHLHIKGLKMSKSLKNFITIRQALSKYTARQIRL 340
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
21-100 |
1.23e-05 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 49.44 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 21 IEKIIQKRWEDAKIF----EVDASdeppKPGEKYFGNFPYPYMNGvLHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHC 96
Cdd:PLN02563 85 IEPKWQRYWEENRTFrtpdDVDTS----KPKFYVLDMFPYPSGAG-LHVGHPEGYTATDILARYKRMQGYNVLHPMGWDA 159
|
....
gi 302755993 97 TGMP 100
Cdd:PLN02563 160 FGLP 163
|
|
| cysS |
PRK14535 |
cysteinyl-tRNA synthetase; Provisional |
707-741 |
6.97e-04 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 173001 [Multi-domain] Cd Length: 699 Bit Score: 43.55 E-value: 6.97e-04
10 20 30
....*....|....*....|....*....|....*
gi 302755993 707 NGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRF 741
Cdd:PRK14535 499 NGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRF 533
|
|
| PLN02946 |
PLN02946 |
cysteine-tRNA ligase |
668-743 |
7.41e-04 |
|
cysteine-tRNA ligase
Pssm-ID: 178532 [Multi-domain] Cd Length: 557 Bit Score: 43.38 E-value: 7.41e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 302755993 668 YPFDLRVSGKDLIQNHLTFSIYNHTAMFPEER---WPRsfrcNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGL 743
Cdd:PLN02946 276 HSFDIHGGGMDLVFPHHENEIAQSCAACCDSNisyWIH----NGFVTVDSEKMSKSLGNFFTIRQVIDLYHPLALRLFL 350
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
21-68 |
1.08e-03 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 43.15 E-value: 1.08e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 302755993 21 IEKIIQKRWEDAKIFEvdASDEPPKPGEKYF---GnfPyPYMNGVLHLGHA 68
Cdd:COG0060 21 REPEILKFWEENDIYE--KSREARAGRPKFVlhdG--P-PYANGDIHIGHA 66
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
658-807 |
2.53e-03 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 42.01 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 658 KRMKKEFDYWYPFDLRVSGKDLIQNHLTFsiYNHTAMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSAD 737
Cdd:PLN02224 310 QNLETAVSFGWPASLHLIGKDILRFHAVY--WPAMLMSAGLELPKMVFGHGFLTKDGMKMGKSLGNTLEPFELVQKFGPD 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302755993 738 ATRF------GLADAGDSVDDaNFVKLT----ANS---------AILRLTKEMAWMSDEVIAAEKDLRKGSPTTFADRVF 798
Cdd:PLN02224 388 AVRYfflrevEFGNDGDYSED-RFIKIVnahlANTignllnrtlGLLKKNCESTLVEDSTVAAEGVPLKDTVEKLVEKAQ 466
|
....*....
gi 302755993 799 ENEINIAIN 807
Cdd:PLN02224 467 TNYENLSLS 475
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
55-115 |
4.64e-03 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 40.59 E-value: 4.64e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 302755993 55 PYPYMNGVLHLGHAFSLSKLEFSAAFQRLCGTKVLLPMGFHCTGMPIKACADKLVRESEEF 115
Cdd:cd00814 7 ALPYVNGVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAEEEGVTPQEL 67
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
21-69 |
7.36e-03 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 40.47 E-value: 7.36e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 302755993 21 IEKIIQKRWEDAKIFEVDASDEPPkpgekyfgnF----PYPYMNGVLHLGHAF 69
Cdd:PRK05729 14 VEAKWYQKWEEKGYFKPDDNSKKP---------FsiviPPPNVTGSLHMGHAL 57
|
|
| |
