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Conserved domains on  [gi|302883642|ref|XP_003040720|]
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uncharacterized protein NECHADRAFT_9895, partial [Fusarium vanettenii 77-13-4]

Protein Classification

DASH complex subunit DAM1( domain architecture ID 10554562)

DASH complex subunit DAM1 is a component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DASH_Dam1 pfam08653
DASH complex subunit Dam1; The DASH complex is a ~10 subunit microtubule-binding complex that ...
 32-85 7.73e-27

DASH complex subunit Dam1; The DASH complex is a ~10 subunit microtubule-binding complex that is transferred to the kinetochore prior to mitosis. In Saccharomyces cerevisiae DASH forms both rings and spiral structures on microtubules in vitro. Components of the DASH complex, including Dam1, Duo1, Spc34, Dad1 and Ask1, are essential and connect the centromere to the plus end of spindle microtubules.


:

Pssm-ID: 430133  Cd Length: 56  Bit Score: 92.61  E-value: 7.73e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 302883642  32 FEPAFAELSDAMADLEANMMHFQLMHESLARFSESFASFMYGLNMNAFCVDFPE 85
Cdd:pfam08653  1 LEPAFAELADSLETLDSNMEQLNQIHEALSDFNESFASFLYGLNMNAWCVDFPE 54
 
Name Accession Description Interval E-value
DASH_Dam1 pfam08653
DASH complex subunit Dam1; The DASH complex is a ~10 subunit microtubule-binding complex that ...
 32-85 7.73e-27

DASH complex subunit Dam1; The DASH complex is a ~10 subunit microtubule-binding complex that is transferred to the kinetochore prior to mitosis. In Saccharomyces cerevisiae DASH forms both rings and spiral structures on microtubules in vitro. Components of the DASH complex, including Dam1, Duo1, Spc34, Dad1 and Ask1, are essential and connect the centromere to the plus end of spindle microtubules.


Pssm-ID: 430133  Cd Length: 56  Bit Score: 92.61  E-value: 7.73e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 302883642  32 FEPAFAELSDAMADLEANMMHFQLMHESLARFSESFASFMYGLNMNAFCVDFPE 85
Cdd:pfam08653  1 LEPAFAELADSLETLDSNMEQLNQIHEALSDFNESFASFLYGLNMNAWCVDFPE 54
 
Name Accession Description Interval E-value
DASH_Dam1 pfam08653
DASH complex subunit Dam1; The DASH complex is a ~10 subunit microtubule-binding complex that ...
 32-85 7.73e-27

DASH complex subunit Dam1; The DASH complex is a ~10 subunit microtubule-binding complex that is transferred to the kinetochore prior to mitosis. In Saccharomyces cerevisiae DASH forms both rings and spiral structures on microtubules in vitro. Components of the DASH complex, including Dam1, Duo1, Spc34, Dad1 and Ask1, are essential and connect the centromere to the plus end of spindle microtubules.


Pssm-ID: 430133  Cd Length: 56  Bit Score: 92.61  E-value: 7.73e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 302883642  32 FEPAFAELSDAMADLEANMMHFQLMHESLARFSESFASFMYGLNMNAFCVDFPE 85
Cdd:pfam08653  1 LEPAFAELADSLETLDSNMEQLNQIHEALSDFNESFASFLYGLNMNAWCVDFPE 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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