|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
88-383 |
9.24e-127 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 366.14 E-value: 9.24e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 88 TLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSAGTS 167
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 168 LYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGEaLSPVSLLADpSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKK 247
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGG-EKGVSALVS-SFRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 248 KGCEQVLWLYGPDHELTEAGTMNIFVFWtheDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRA 327
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 335289923 328 LehgrvrEVFGSGTACQVCPVHRILYQGKFlhiPTMENGPELILRFYNELKMIQYG 383
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
40-393 |
1.76e-122 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 358.31 E-value: 1.76e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 40 EMTREPHKKPDPSEcLLFGKTFTDHMLMVEWNMEKgWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLF 119
Cdd:PRK13357 8 NPTSDEKRAIDWAN-LGFGYVFTDHMVVIDYKDGK-WHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 120 RPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSA-GTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPV 198
Cdd:PRK13357 86 RPDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGeGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 199 GAYFPGEAlSPVSLLADPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIF-VFwt 276
Cdd:PRK13357 166 GAYFKGGV-KPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFfIT-- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 277 hEDGaleLVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRALEHGRVREVFGSGTACQVCPVHRILYQGK 356
Cdd:PRK13357 243 -KDG---TVTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDK 317
|
330 340 350
....*....|....*....|....*....|....*....
gi 335289923 357 FLHIPTMENGPeLILRFYNELKMIQYGTKA--HEWMLQV 393
Cdd:PRK13357 318 EFVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
76-393 |
4.26e-94 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 284.34 E-value: 4.26e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 76 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEV 155
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 156 DRDWVPDS-AGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGeALSPVSLLADPSFIRAWVGGVGDCKIGGN 234
Cdd:TIGR01123 81 NKDWVPPYgSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKG-GLAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 235 YGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIFvFWTHeDGalELVTPALDGIILPGVVRQSLLDLARTWGeFR 313
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFF-FITG-DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 314 VTERKMTMNEFLRALEHGrvREVFGSGTACQVCPVHRILYQGKFLHIPTMENGpELILRFYNELKMIQYGTKA--HEWML 391
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGDFEdpYGWIV 311
|
..
gi 335289923 392 QV 393
Cdd:TIGR01123 312 EV 313
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
76-386 |
1.71e-65 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 210.05 E-value: 1.71e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 76 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVE 154
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 155 VDRDwvpdsagTSLYVRPVLIGNEPSLGVGSPTH-ALLYVILCPVGAYFPGEALSPVSLLADPsFIRAWVGGVGDCKiGG 233
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEYePTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 234 NYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGe 311
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL---DTDgyVAEGSGSNVFIV---KDG--VLVTPPLSGGILPGITRDSVIELARELG- 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 335289923 312 FRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRIlyQGKflHIPTMENGPeLILRFYNELKMIQYGTKA 386
Cdd:COG0115 221 IPVEERPISLEELYTA------DEVFLTGTAAEVTPVTEI--DGR--PIGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
101-351 |
1.27e-29 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 113.99 E-value: 1.27e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 101 QLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVDRDWVPdsagtslYVRPVLIGNEP 179
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 180 SLGVGSPT-HALLYVILCPVGAYFPGEALSPVSLLADPSFIRAwvggvgDCKiGGNYGPTVFVQKEAKKKGCEQVLwLYG 258
Cdd:pfam01063 69 GFGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 259 PDHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFG 338
Cdd:pfam01063 141 EDGNVTEGSTSNVFLV---KGG--TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 335289923 339 SGTACQVCPVHRI 351
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
88-383 |
9.24e-127 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 366.14 E-value: 9.24e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 88 TLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSAGTS 167
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 168 LYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGEaLSPVSLLADpSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKK 247
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGG-EKGVSALVS-SFRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 248 KGCEQVLWLYGPDHELTEAGTMNIFVFWtheDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRA 327
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 335289923 328 LehgrvrEVFGSGTACQVCPVHRILYQGKFlhiPTMENGPELILRFYNELKMIQYG 383
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
40-393 |
1.76e-122 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 358.31 E-value: 1.76e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 40 EMTREPHKKPDPSEcLLFGKTFTDHMLMVEWNMEKgWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLF 119
Cdd:PRK13357 8 NPTSDEKRAIDWAN-LGFGYVFTDHMVVIDYKDGK-WHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 120 RPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSA-GTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPV 198
Cdd:PRK13357 86 RPDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGeGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 199 GAYFPGEAlSPVSLLADPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIF-VFwt 276
Cdd:PRK13357 166 GAYFKGGV-KPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFfIT-- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 277 hEDGaleLVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRALEHGRVREVFGSGTACQVCPVHRILYQGK 356
Cdd:PRK13357 243 -KDG---TVTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDK 317
|
330 340 350
....*....|....*....|....*....|....*....
gi 335289923 357 FLHIPTMENGPeLILRFYNELKMIQYGTKA--HEWMLQV 393
Cdd:PRK13357 318 EFVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
76-393 |
4.26e-94 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 284.34 E-value: 4.26e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 76 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEV 155
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 156 DRDWVPDS-AGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGeALSPVSLLADPSFIRAWVGGVGDCKIGGN 234
Cdd:TIGR01123 81 NKDWVPPYgSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKG-GLAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 235 YGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIFvFWTHeDGalELVTPALDGIILPGVVRQSLLDLARTWGeFR 313
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFF-FITG-DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 314 VTERKMTMNEFLRALEHGrvREVFGSGTACQVCPVHRILYQGKFLHIPTMENGpELILRFYNELKMIQYGTKA--HEWML 391
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGDFEdpYGWIV 311
|
..
gi 335289923 392 QV 393
Cdd:TIGR01123 312 EV 313
|
|
| PLPDE_IV |
cd00449 |
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, ... |
94-377 |
2.73e-77 |
|
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate lyases (ADCL). BCAT catalyzes the reversible transamination reaction between the L-branched-chain amino and alpha-keto acids. DAAT catalyzes the synthesis of D-glutamic acid and D-alanine, and ADCL converts 4-amino-4-deoxychorismate to p-aminobenzoate and pyruvate. Except for a few enzymes, i. e., Escherichia coli and Salmonella BCATs, which are homohexamers arranged as a double trimer, the class IV PLPDEs are homodimers. Homodimer formation is required for catalytic activity.
Pssm-ID: 238254 [Multi-domain] Cd Length: 256 Bit Score: 239.43 E-value: 2.73e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 94 SALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVdrdwvpdSAGTSLYVRP 172
Cdd:cd00449 2 RGLHYGDGVFEGLRAGKG-----RLFRLDEHLDRLNRSAKRLGLPiPYDREELREALKELVAA-------NNGASLYIRP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 173 VLIGNEPSLGVGSPTH--ALLYVILCPVGAYFPGeALSPVSLLADPSFIRAWVGGVGDCKIGGNYgPTVFVQKEAKKKGC 250
Cdd:cd00449 70 LLTRGVGGLGVAPPPSpePTFVVFASPVGAYAKG-GEKGVRLITSPDRRRAAPGGTGDAKTGGNL-NSVLAKQEAAEAGA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 251 EQVLWLYGPDHeLTEAGTMNIFVFWtheDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAleh 330
Cdd:cd00449 148 DEALLLDDNGY-VTEGSASNVFIVK---DG--ELVTPPLDGGILPGITRDSVIELAKELG-IKVEERPISLDELYAA--- 217
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 335289923 331 grvREVFGSGTACQVCPVHRILYQGKFlhiptMENGPELILRFYNEL 377
Cdd:cd00449 218 ---DEVFLTGTAAEVTPVTEIDGRGIG-----DGKPGPVTRKLRELL 256
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
76-386 |
1.71e-65 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 210.05 E-value: 1.71e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 76 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVE 154
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 155 VDRDwvpdsagTSLYVRPVLIGNEPSLGVGSPTH-ALLYVILCPVGAYFPGEALSPVSLLADPsFIRAWVGGVGDCKiGG 233
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEYePTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 234 NYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGe 311
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL---DTDgyVAEGSGSNVFIV---KDG--VLVTPPLSGGILPGITRDSVIELARELG- 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 335289923 312 FRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRIlyQGKflHIPTMENGPeLILRFYNELKMIQYGTKA 386
Cdd:COG0115 221 IPVEERPISLEELYTA------DEVFLTGTAAEVTPVTEI--DGR--PIGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| PLN02782 |
PLN02782 |
Branched-chain amino acid aminotransferase |
57-356 |
1.56e-61 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 215418 Cd Length: 403 Bit Score: 203.54 E-value: 1.56e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 57 FGKTFTDHMLMVEWNMEKGWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLC 136
Cdd:PLN02782 77 FGLVPTDYMYIMKCNRDGEFSKGELQRFGNIELSPSAGVLNYGQGLFEGLKAYRKEDGNILLFRPEENAIRMRNGAERMC 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 137 LPSFDKVELLECIRRLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPgEALSPVSLLADP 216
Cdd:PLN02782 157 MPAPTVEQFVEAVKETVLANKRWVPPPGKGSLYIRPLLMGSGAVLGLAPAPEYTFLIYVSPVGNYFK-EGVAPINLIVEN 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 217 SFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLygpD--HE--LTEAGTMNIFVFwthEDGALElvTPALDGI 292
Cdd:PLN02782 236 EFHRATPGGTGGVKTIGNYAAVLKAQSIAKAKGYSDVLYL---DcvHKkyLEEVSSCNIFIV---KDNVIS--TPAIKGT 307
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 335289923 293 ILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQGK 356
Cdd:PLN02782 308 ILPGITRKSIIDVARSQG-FQVEERNVTVDELLEA------DEVFCTGTAVVVSPVGSITYKGK 364
|
|
| PLN03117 |
PLN03117 |
Branched-chain-amino-acid aminotransferase; Provisional |
53-393 |
8.89e-54 |
|
Branched-chain-amino-acid aminotransferase; Provisional
Pssm-ID: 178664 Cd Length: 355 Bit Score: 182.05 E-value: 8.89e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 53 ECLLFGKTFTDHMLMVEWNMEKGWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSA 132
Cdd:PLN03117 23 EELGFALVPTDYMYVAKCKQGESFSEGKIVPYGDISISPCAGILNYGQGLFEGLKAYRTEDGRITLFRPDQNALRMQTGA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 133 LRLCLPSFDKVELLECIRRLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFpgEALSPVSL 212
Cdd:PLN03117 103 DRLCMTPPSLEQFVEAVKQTVLANKKWVPPPGKGTLYIRPLLIGSGAVLGVAPAPEYTFLIYASPVGNYH--KASSGLNL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 213 LADPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWL-YGPDHELTEAGTMNIFVFwtheDGALeLVTPALDG 291
Cdd:PLN03117 181 KVDHKHRRAHSGGTGGVKSCTNYSPVVKSLIEAKSSGFSDVLFLdAATGKNIEELSACNIFIL----KGNI-VSTPPTSG 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 292 IILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQGKFLHIPTMENGpeLIL 371
Cdd:PLN03117 256 TILPGVTRKSISELARDIG-YQVEERDVSVDELLEA------EEVFCTGTAVVVKAVETVTFHDKKVKYRTGEEA--LST 326
|
330 340
....*....|....*....|....
gi 335289923 372 RFYNELKMIQYGTKAHE--WMLQV 393
Cdd:PLN03117 327 KLHLILTNIQMGVVEDKkgWMVEI 350
|
|
| PLN02259 |
PLN02259 |
branched-chain-amino-acid aminotransferase 2 |
55-364 |
4.82e-47 |
|
branched-chain-amino-acid aminotransferase 2
Pssm-ID: 177901 Cd Length: 388 Bit Score: 165.28 E-value: 4.82e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 55 LLFGKTFTDHMLMVEWNMEKGWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALR 134
Cdd:PLN02259 61 LGFGLNPADYMYVMKCSKDGEFTQGELSPYGNIQLSPSAGVLNYGQAIYEGTKAYRKENGKLLLFRPDHNAIRMKLGAER 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 135 LCLPSFDKVELLECIRRLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPgEALSPVSLLA 214
Cdd:PLN02259 141 MLMPSPSVDQFVNAVKQTALANKRWVPPAGKGTLYIRPLLMGSGPILGLGPAPEYTFIVYASPVGNYFK-EGMAALNLYV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 215 DPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIFVFwthedGALELVTPALDGII 293
Cdd:PLN02259 220 EEEYVRAAPGGAGGVKSITNYAPVLKALSRAKSRGFSDVLYLDSVKKKyLEEASSCNVFVV-----KGRTISTPATNGTI 294
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 335289923 294 LPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQGKFLHIPTME 364
Cdd:PLN02259 295 LEGITRKSVMEIASDQG-YQVVEKAVHVDEVMDA------DEVFCTGTAVVVAPVGTITYQEKRVEYKTGD 358
|
|
| PLN02883 |
PLN02883 |
Branched-chain amino acid aminotransferase |
71-354 |
1.02e-46 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 178471 Cd Length: 384 Bit Score: 164.12 E-value: 1.02e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 71 NMEKGWgrprIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIR 150
Cdd:PLN02883 77 NFEQGY----LSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRILLFRPELNAMRMKIGAERMCMHSPSVHQFIEGVK 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 151 RLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPgEALSPVSLLADPSFIRAWVGGVGDCK 230
Cdd:PLN02883 153 QTVLANRRWVPPPGKGSLYLRPLLFGSGASLGVAAAPEYTFLVFGSPVQNYFK-EGTAALNLYVEEVIPRAYLGGTGGVK 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 231 IGGNYGPTVFVQKEAKKKGCEQVLWLYG-PDHELTEAGTMNIFVFWTHedgalELVTPALDGIILPGVVRQSLLDLARTW 309
Cdd:PLN02883 232 AISNYGPVLEVMRRAKSRGFSDVLYLDAdTGKNIEEVSAANIFLVKGN-----IIVTPATSGTILGGITRKSIIEIALDL 306
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 335289923 310 GeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQ 354
Cdd:PLN02883 307 G-YKVEERRVPVEELKEA------EEVFCTGTAAGVASVGSITFK 344
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
101-351 |
1.27e-29 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 113.99 E-value: 1.27e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 101 QLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVDRDWVPdsagtslYVRPVLIGNEP 179
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 180 SLGVGSPT-HALLYVILCPVGAYFPGEALSPVSLLADPSFIRAwvggvgDCKiGGNYGPTVFVQKEAKKKGCEQVLwLYG 258
Cdd:pfam01063 69 GFGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 259 PDHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFG 338
Cdd:pfam01063 141 EDGNVTEGSTSNVFLV---KGG--TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 335289923 339 SGTACQVCPVHRI 351
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| PRK06606 |
PRK06606 |
branched-chain amino acid transaminase; |
83-351 |
5.11e-27 |
|
branched-chain amino acid transaminase;
Pssm-ID: 235841 Cd Length: 306 Bit Score: 109.08 E-value: 5.11e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 83 PFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVrLFRPWLNMDRMLRSA--LRLCLPsFDKVELLECIRRLVEVDRdwv 160
Cdd:PRK06606 17 PWEDAKVHVLTHALHYGTGVFEGIRAYDTPKGPA-IFRLREHTKRLFNSAkiLRMEIP-YSVDELMEAQREVVRKNN--- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 161 PDSAgtslYVRP-VLIGNEpSLGV---GSPTHALLYVIlcPVGAYFPGEALSP-----VSlladpSFIRAWVGGV-GDCK 230
Cdd:PRK06606 92 LKSA----YIRPlVFVGDE-GLGVrphGLPTDVAIAAW--PWGAYLGEEALEKgirvkVS-----SWTRHAPNSIpTRAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 231 IGGNYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLART 308
Cdd:PRK06606 160 ASGNYLNSILAKTEARRNGYDEALLL---DVEgyVSEGSGENIFIV---RDG--VLYTPPLTSSILEGITRDTVITLAKD 231
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 335289923 309 WGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 351
Cdd:PRK06606 232 LG-IEVIERRITRDELYIA------DEVFFTGTAAEVTPIREV 267
|
|
| ilvE_I |
TIGR01122 |
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are ... |
83-351 |
9.10e-24 |
|
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family more strongly similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130192 Cd Length: 298 Bit Score: 100.13 E-value: 9.10e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 83 PFQNLTLHPACSALHYSLQLFEGLKAYKgGDQRVRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVdrdwvp 161
Cdd:TIGR01122 8 DWEDAKVHVLTHALHYGTGVFEGIRAYD-TDKGPAIFRLKEHIQRLYDSAKIYRMEiPYSKEELMEATRETLRK------ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 162 dSAGTSLYVRPVLIGNEPSLGV----GSPTHalLYVILCPVGAYFPGEALSPVSLLADPSFIRAWVGGV-GDCKIGGNYG 236
Cdd:TIGR01122 81 -NNLRSAYIRPLVFRGDGDLGLnpraGYKPD--VIIAAWPWGAYLGEEALEKGIDAKVSSWRRNAPNTIpTAAKAGGNYL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 237 PTVFVQKEAKKKGCEQVLWLyGPDHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTE 316
Cdd:TIGR01122 158 NSLLAKSEARRHGYDEAILL-DVEGYVAEGSGENIFIV---KDG--VLFTPPVTSSILPGITRDTVITLAKELG-IEVVE 230
|
250 260 270
....*....|....*....|....*....|....*
gi 335289923 317 RKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 351
Cdd:TIGR01122 231 QPISREELYTA------DEAFFTGTAAEITPIREV 259
|
|
| D-AAT_like |
cd01558 |
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes ... |
103-351 |
1.46e-18 |
|
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.
Pssm-ID: 238799 [Multi-domain] Cd Length: 270 Bit Score: 84.57 E-value: 1.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 103 FEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLPS-FDKVELLECIRRLVEvdRDWVPDSAGtslYVRpVLIGNEP-S 180
Cdd:cd01558 28 YEVIRVYNG-----KPFALDEHLDRLYRSAKELRIDIpYTREELKELIRELVA--KNEGGEGDV---YIQ-VTRGVGPrG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 181 LGVGSPTHALLYVILCPVGAYFPGEALSPVSLLADPsFIRaWvggvGDCKI-GGNYGPTVFVQKEAKKKGCEQVlWLYGP 259
Cdd:cd01558 97 HDFPKCVKPTVVIITQPLPLPPAELLEKGVRVITVP-DIR-W----LRCDIkSLNLLNNVLAKQEAKEAGADEA-ILLDA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 260 DHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGS 339
Cdd:cd01558 170 DGLVTEGSSSNVFIV---KNG--VLVTPPLDNGILPGITRATVIELAKELG-IPVEERPFSLEELYTA------DEVFLT 237
|
250
....*....|..
gi 335289923 340 GTACQVCPVHRI 351
Cdd:cd01558 238 STTAEVMPVVEI 249
|
|
| ADCL_like |
cd01559 |
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent ... |
95-351 |
1.58e-14 |
|
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.
Pssm-ID: 238800 [Multi-domain] Cd Length: 249 Bit Score: 72.73 E-value: 1.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 95 ALHYSLQLFEGLKAYKGgdqRVRLFRPWLnmDRMLRSALRLCLPSFDKVELLeciRRLVEVDRDWVPDSAGTSL-YVRPV 173
Cdd:cd01559 3 GFAYGDGVFETMRALDG---RLFLLDAHL--ARLERSARRLGIPEPDLPRLR---AALESLLAANDIDEGRIRLiLSRGP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 174 LIGNEPSLGVGSPTHaLLYVILCPVGAYFPGEALSPVSL-LADPSFIrawvGGVGDCkiggNYGPTVFVQKEAKKKGCEQ 252
Cdd:cd01559 75 GGRGYAPSVCPGPAL-YVSVIPLPPAWRQDGVRLITCPVrLGEQPLL----AGLKHL----NYLENVLAKREARDRGADE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 253 VLWLyGPDHELTEAGTMNifVFWTHeDGalELVTPALDGIILPGVVRQSLLDLARTWGEfRVTERKMTMNEFLRAlehgr 332
Cdd:cd01559 146 ALFL-DTDGRVIEGTASN--LFFVK-DG--ELVTPSLDRGGLAGITRQRVIELAAAKGY-AVDERPLRLEDLLAA----- 213
|
250
....*....|....*....
gi 335289923 333 vREVFGSGTACQVCPVHRI 351
Cdd:cd01559 214 -DEAFLTNSLLGVAPVTAI 231
|
|
| PRK08320 |
PRK08320 |
branched-chain amino acid aminotransferase; Reviewed |
103-356 |
1.13e-11 |
|
branched-chain amino acid aminotransferase; Reviewed
Pssm-ID: 236238 [Multi-domain] Cd Length: 288 Bit Score: 64.89 E-value: 1.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 103 FEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCL-PSFDKVELLECIRRLVEVD--RDwvpdsagtsLYVRPVLignep 179
Cdd:PRK08320 33 FEGIRAYNG-----RVFRLKEHIDRLYDSAKAIMLeIPLSKEEMTEIVLETLRKNnlRD---------AYIRLVV----- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 180 SLGVGS----------PThalLYVILCPVGAYfPGEaLSPVSLLADPSFIRAWVGGVGDCKIGG-NYGPTVFVQKEAKKK 248
Cdd:PRK08320 94 SRGVGDlgldprkcpkPT---VVCIAEPIGLY-PGE-LYEKGLKVITVSTRRNRPDALSPQVKSlNYLNNILAKIEANLA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 249 GCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGALelVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLR 326
Cdd:PRK08320 169 GVDEAIML---NDEgyVAEGTGDNIFIV---KNGKL--ITPPTYAGALEGITRNAVIEIAKELG-IPVREELFTLHDLYT 239
|
250 260 270
....*....|....*....|....*....|....
gi 335289923 327 AlehgrvREVFGSGTACQVCPV----HRILYQGK 356
Cdd:PRK08320 240 A------DEVFLTGTAAEVIPVvkvdGRVIGDGK 267
|
|
| PRK07544 |
PRK07544 |
branched-chain amino acid aminotransferase; Validated |
83-351 |
1.15e-09 |
|
branched-chain amino acid aminotransferase; Validated
Pssm-ID: 181025 Cd Length: 292 Bit Score: 58.83 E-value: 1.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 83 PFQNLTLHPACSALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVeVDRDWVPD 162
Cdd:PRK07544 19 PWRDAKVHVLTHGLHYASSVFEGERAYGG-----KIFKLREHSERLRRSAELLDFEIPYSVAEIDAAKKET-LAANGLTD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 163 SagtslYVRPVLIGNEPSLGVGSPTHALLYVILC-PVGAYFPGEA-LSPVSL-LA-----DPSFIRAwvggvgDCKIGGN 234
Cdd:PRK07544 93 A-----YVRPVAWRGSEMMGVSAQQNKIHLAIAAwEWPSYFDPEAkMKGIRLdIAkwrrpDPETAPS------AAKAAGL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 235 YGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGALElvTPALDgIILPGVVRQSLLDLARTWGeF 312
Cdd:PRK07544 162 YMICTISKHAAEAKGYADALML---DYRgyVAEATGANIFFV---KDGVIH--TPTPD-CFLDGITRQTVIELAKRRG-I 231
|
250 260 270
....*....|....*....|....*....|....*....
gi 335289923 313 RVTERKMtMNEFLRALEhgrvrEVFGSGTACQVCPVHRI 351
Cdd:PRK07544 232 EVVERHI-MPEELAGFS-----ECFLTGTAAEVTPVSEI 264
|
|
| PRK13356 |
PRK13356 |
branched-chain amino acid aminotransferase; |
123-351 |
1.56e-07 |
|
branched-chain amino acid aminotransferase;
Pssm-ID: 237362 Cd Length: 286 Bit Score: 52.26 E-value: 1.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 123 LNMDRMLRSALRLCL-PSFDKVEL----LECIRRLvevdrdwvpdSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCP 197
Cdd:PRK13356 52 LHCARVNRSAEALGLkPTVSAEEIealaREGLKRF----------DPDTALYIRPMYWAEDGFASGVAPDPESTRFALCL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 198 VGAYFPGEALSPVSLladPSFIRAWVG-GVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHeLTEAGTMNIFVFwt 276
Cdd:PRK13356 122 EEAPMPEPTGFSLTL---SPFRRPTLEmAPTDAKAGCLYPNNARALREARSRGFDNALVLDMLGN-VAETATSNVFMV-- 195
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 335289923 277 hEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 351
Cdd:PRK13356 196 -KDG--VVFTPVPNGTFLNGITRQRVIALLREDG-VTVVETTLTYEDFLEA------DEVFSTGNYSKVVPVTRF 260
|
|
| PRK12400 |
PRK12400 |
D-amino acid aminotransferase; Reviewed |
96-348 |
6.34e-07 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 171470 Cd Length: 290 Bit Score: 50.40 E-value: 6.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 96 LHYSLQLFEGLKAYKGGdqrVRLFRPwlNMDRMLRS--ALRLCLPsFDKVELLECIRRLVEvDRDWVPDsaGTsLYVrpv 173
Cdd:PRK12400 30 LQFGDGVYEVIRLYKGN---FHLLDP--HITRLYRSmeEIELTLP-FSKAELITLLYKLIE-NNNFHED--GT-IYL--- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 174 lignEPSLGVGSPTHALLYVILCPVGAYfpgealspVSLLADPSF-----IRA-------WVggvgDCKIGG-NYGPTVF 240
Cdd:PRK12400 97 ----QVSRGVQARTHTFSYDVPPTIYAY--------ITKKERPALwieygVRAisepdtrWL----RCDIKSlNLLPNIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 241 VQKEAKKKGCEQVLWLYgpDHELTEAGTMNIFVFwthEDGALeLVTPAlDGIILPGVVRQSLLDLARTWgEFRVTERKMT 320
Cdd:PRK12400 161 AATKAERKGCKEALFVR--NGTVTEGSHSNFFLI---KNGTL-YTHPA-NHLILNGIIRQYVLSLAKTL-RIPVQEELFS 232
|
250 260
....*....|....*....|....*...
gi 335289923 321 MNEFLRAlehgrvREVFGSGTACQVCPV 348
Cdd:PRK12400 233 VRDVYQA------DECFFTGTTIEILPM 254
|
|
| PRK06680 |
PRK06680 |
D-amino acid aminotransferase; Reviewed |
237-351 |
6.95e-06 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 180656 [Multi-domain] Cd Length: 286 Bit Score: 47.23 E-value: 6.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 237 PTVFVQKEAKKKGCeQVLWLYGpDHELTEAGTMNIFVfwTHEDGALelVTPALDGIILPGVVRQSLLDLARTWGeFRVTE 316
Cdd:PRK06680 155 PNVLAKQAAKEAGA-QEAWMVD-DGFVTEGASSNAWI--VTKDGKL--VTRPADNFILPGITRHTLIDLAKELG-LEVEE 227
|
90 100 110
....*....|....*....|....*....|....*
gi 335289923 317 RKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 351
Cdd:PRK06680 228 RPFTLQEAYAA------REAFITAASSFVFPVVQI 256
|
|
| PRK07849 |
PRK07849 |
aminodeoxychorismate lyase; |
103-327 |
4.97e-05 |
|
aminodeoxychorismate lyase;
Pssm-ID: 236114 [Multi-domain] Cd Length: 292 Bit Score: 44.56 E-value: 4.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 103 FEGLKAYKGgdqRVRLFRPWLnmDRMLRSALRLCLPSFDkvelLECIRRLVE-VDRDWvpDSAGTSLYVRPVLignepSL 181
Cdd:PRK07849 42 FETLLVRDG---RPCNLEAHL--ERLARSAALLDLPEPD----LDRWRRAVElAIEEW--RAPEDEAALRLVY-----SR 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 182 GVGSPTHALLYVILCPVGAYFPGEALSPVSLLADPsfiRAWVGGVGDCK---IGG----NYGPTVFVQKEAKKKGCEQVL 254
Cdd:PRK07849 106 GRESGGAPTAWVTVSPVPERVARARREGVSVITLD---RGYPSDAAERApwlLAGaktlSYAVNMAALRYAARRGADDVI 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 335289923 255 WLyGPDHELTEAGTMNifVFWTHEDgalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRA 327
Cdd:PRK07849 183 FT-STDGYVLEGPTST--VVIATDD---RLLTPPPWYGILPGTTQAALFEVAREKG-WDCEYRALRPADLFAA 248
|
|
| PLN02845 |
PLN02845 |
Branched-chain-amino-acid aminotransferase-like protein |
234-329 |
2.00e-04 |
|
Branched-chain-amino-acid aminotransferase-like protein
Pssm-ID: 215454 [Multi-domain] Cd Length: 336 Bit Score: 43.08 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 335289923 234 NYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIfVFWTHEDgalELVTPALDGiILPGVVRQSLLDLA---RT 308
Cdd:PLN02845 188 NYLPNALSQMEAEERGAFAGIWL---DEEgfVAEGPNMNV-AFLTNDG---ELVLPPFDK-ILSGCTARRVLELAprlVS 259
|
90 100
....*....|....*....|..
gi 335289923 309 WGEFR-VTERKMTMNEFLRALE 329
Cdd:PLN02845 260 PGDLRgVKQRKISVEEAKAADE 281
|
|
| |
