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Conserved domains on  [gi|410084753|ref|XP_003959953|]
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hypothetical protein KAFR_0L02070 [Kazachstania africana CBS 2517]

Protein Classification

RPM2 superfamily-containing protein( domain architecture ID 713562)

RPM2 superfamily-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPM2 super family cl28674
Mitochondrial ribonuclease P subunit (RPM2); Ribonuclease P (RNase P) generates mature tRNA ...
 195-311 2.56e-36

Mitochondrial ribonuclease P subunit (RPM2); Ribonuclease P (RNase P) generates mature tRNA molecules by cleaving their 5' ends. RPM2 is a protein subunit of the yeast mitochondrial RNase P. It has the ability to act as transcriptional activator in the nucleus where it plays a role in defining the steady-state levels of mRNAs for some nucleus-encoded mitochondrial components.


The actual alignment was detected with superfamily member pfam08579:

Pssm-ID: 369970 [Multi-domain]  Cd Length: 119  Bit Score: 133.34  E-value: 2.56e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410084753   195 QDDEDPWEKDTDESLNKTTFLQTHIDQINNCYRIEDYNKINSLYQSLKRNNIVPPIEIYEKIFDSFNKRNFDQNTnllIN 274
Cdd:pfam08579    5 DEAYPEWEEDTEPCLNESTFLHTQIKEIEACYEKKNYNKINALYQSLKRNGIVPPLELFEQVLKSICRRDLDNND---ID 81

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 410084753   275 EKMYQLLNCYQDLINSKLKPTTTIYNSLLEQIFKNSI 311
Cdd:pfam08579   82 NKMFELLTCYQDIIVNKLKPNKEIYNIVLGSLLKGSI 118
 
Name Accession Description Interval E-value
RPM2 pfam08579
Mitochondrial ribonuclease P subunit (RPM2); Ribonuclease P (RNase P) generates mature tRNA ...
 195-311 2.56e-36

Mitochondrial ribonuclease P subunit (RPM2); Ribonuclease P (RNase P) generates mature tRNA molecules by cleaving their 5' ends. RPM2 is a protein subunit of the yeast mitochondrial RNase P. It has the ability to act as transcriptional activator in the nucleus where it plays a role in defining the steady-state levels of mRNAs for some nucleus-encoded mitochondrial components.


Pssm-ID: 369970 [Multi-domain]  Cd Length: 119  Bit Score: 133.34  E-value: 2.56e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410084753   195 QDDEDPWEKDTDESLNKTTFLQTHIDQINNCYRIEDYNKINSLYQSLKRNNIVPPIEIYEKIFDSFNKRNFDQNTnllIN 274
Cdd:pfam08579    5 DEAYPEWEEDTEPCLNESTFLHTQIKEIEACYEKKNYNKINALYQSLKRNGIVPPLELFEQVLKSICRRDLDNND---ID 81

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 410084753   275 EKMYQLLNCYQDLINSKLKPTTTIYNSLLEQIFKNSI 311
Cdd:pfam08579   82 NKMFELLTCYQDIIVNKLKPNKEIYNIVLGSLLKGSI 118
 
Name Accession Description Interval E-value
RPM2 pfam08579
Mitochondrial ribonuclease P subunit (RPM2); Ribonuclease P (RNase P) generates mature tRNA ...
 195-311 2.56e-36

Mitochondrial ribonuclease P subunit (RPM2); Ribonuclease P (RNase P) generates mature tRNA molecules by cleaving their 5' ends. RPM2 is a protein subunit of the yeast mitochondrial RNase P. It has the ability to act as transcriptional activator in the nucleus where it plays a role in defining the steady-state levels of mRNAs for some nucleus-encoded mitochondrial components.


Pssm-ID: 369970 [Multi-domain]  Cd Length: 119  Bit Score: 133.34  E-value: 2.56e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410084753   195 QDDEDPWEKDTDESLNKTTFLQTHIDQINNCYRIEDYNKINSLYQSLKRNNIVPPIEIYEKIFDSFNKRNFDQNTnllIN 274
Cdd:pfam08579    5 DEAYPEWEEDTEPCLNESTFLHTQIKEIEACYEKKNYNKINALYQSLKRNGIVPPLELFEQVLKSICRRDLDNND---ID 81

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 410084753   275 EKMYQLLNCYQDLINSKLKPTTTIYNSLLEQIFKNSI 311
Cdd:pfam08579   82 NKMFELLTCYQDIIVNKLKPNKEIYNIVLGSLLKGSI 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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