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Conserved domains on  [gi|513002865|ref|XP_004862923|]
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small glutamine-rich tetratricopeptide repeat-containing protein beta isoform X2 [Heterocephalus glaber]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1008527)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
92-200 1.83e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 96.23  E-value: 1.83e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100
                 ....*....|....*....|....*....
gi 513002865 172 AVRSYQKALDLDPENDSYKSNLKIAEQKL 200
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLEL 123
SGTA_dimer super family cl24944
Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA ...
 5-64 2.27e-10

Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerization domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerization domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.


The actual alignment was detected with superfamily member pfam16546:

Pssm-ID: 465168  Cd Length: 64  Bit Score: 55.60  E-value: 2.27e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 513002865    5 KHLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISLEDTHLAV----SQPLTEMFTN 64
Cdd:pfam16546   1 KRLALSIIDFLSTSLSDGTLSEDDAESLEVAIQCIAEAFEVDPDDEAAVVkafgGQSLLEIFEV 64
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
92-200 1.83e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 96.23  E-value: 1.83e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100
                 ....*....|....*....|....*....
gi 513002865 172 AVRSYQKALDLDPENDSYKSNLKIAEQKL 200
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLEL 123
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 85-233 8.09e-21

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 91.00  E-value: 8.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 513002865 165 AMNKFEEAVRSYQKALDLDPENDSYKSNLKIAEQKLRETGTGLSFDMASLINNPAFISMAASLMQNPQV 233
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEKDLVQPVPSDLPSSVTAPPVEEADATPVV 150
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 85-202 5.80e-12

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 65.78  E-value: 5.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNnAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPD-PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYD 205

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 513002865  165 AMNKFEEAVRSYQKALDLDPENDSYKSNL------KIAEQKLRE 202
Cdd:TIGR00990 206 GLGKYADALLDLTASCIIDGFRNEQSAQAverllkKFAESKAKE 249
SGTA_dimer pfam16546
Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA ...
 5-64 2.27e-10

Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerization domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerization domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.


Pssm-ID: 465168  Cd Length: 64  Bit Score: 55.60  E-value: 2.27e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 513002865    5 KHLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISLEDTHLAV----SQPLTEMFTN 64
Cdd:pfam16546   1 KRLALSIIDFLSTSLSDGTLSEDDAESLEVAIQCIAEAFEVDPDDEAAVVkafgGQSLLEIFEV 64
TPR_1 pfam00515
Tetratricopeptide repeat;
153-186 1.83e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 46.65  E-value: 1.83e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 513002865  153 SKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEN 186
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 153-186 8.93e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.74  E-value: 8.93e-07
                           10        20        30
                   ....*....|....*....|....*....|....
gi 513002865   153 SKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEN 186
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 128-187 9.64e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.47  E-value: 9.64e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 513002865 128 AQSKL--SHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEND 187
Cdd:cd24142    7 AEELLdqGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGG 68
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
92-200 1.83e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 96.23  E-value: 1.83e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100
                 ....*....|....*....|....*....
gi 513002865 172 AVRSYQKALDLDPENDSYKSNLKIAEQKL 200
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLEL 123
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 85-193 4.25e-22

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 96.22  E-value: 4.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:COG3914  112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                         90       100
                 ....*....|....*....|....*....
gi 513002865 165 AMNKFEEAVRSYQKALDLDPENDSYKSNL 193
Cdd:COG3914  192 DLGRLEEAIAAYRRALELDPDNADAHSNL 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
92-202 6.09e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 91.99  E-value: 6.09e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                         90       100       110
                 ....*....|....*....|....*....|.
gi 513002865 172 AVRSYQKALDLDPENDSYKSNLKIAEQKLRE 202
Cdd:COG0457  129 AIEAYERALELDPDDADALYNLGIALEKLGR 159
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 85-233 8.09e-21

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 91.00  E-value: 8.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 513002865 165 AMNKFEEAVRSYQKALDLDPENDSYKSNLKIAEQKLRETGTGLSFDMASLINNPAFISMAASLMQNPQV 233
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEKDLVQPVPSDLPSSVTAPPVEEADATPVV 150
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
85-205 2.15e-20

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 87.28  E-value: 2.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:COG4785   73 AQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALY 152

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 513002865 165 AMNKFEEAVRSYQKALDLDPENDSYKSNLKIAEQKLRETGT 205
Cdd:COG4785  153 YLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKA 193
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 85-193 9.85e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 89.28  E-value: 9.85e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:COG3914   78 AALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALR 157

                         90       100
                 ....*....|....*....|....*....
gi 513002865 165 AMNKFEEAVRSYQKALDLDPENDSYKSNL 193
Cdd:COG3914  158 RLGRLEEAIAALRRALELDPDNAEALNNL 186
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 92-187 7.36e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 80.82  E-value: 7.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                         90
                 ....*....|....*.
gi 513002865 172 AVRSYQKALDLDPEND 187
Cdd:COG4235  104 AIAAWQKLLALLPADA 119
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 83-204 7.69e-19

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 81.01  E-value: 7.69e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  83 GKADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLA 162
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 513002865 163 LTAMNKFEEAVRSYQKALDLDPENDSYKSNLKIAEQKLRETG 204
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPD 123
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
112-200 1.56e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 82.75  E-value: 1.56e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865 112 IELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDPENDSYKS 191
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80


                 ....*....
gi 513002865 192 NLKIAEQKL 200
Cdd:COG0457   81 NLGLALQAL 89
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-209 1.66e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.54  E-value: 1.66e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  74 LENLVPEDVGKADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYS 153
Cdd:COG2956   99 LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCA 178

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 513002865 154 KAYGRMGLALTAMNKFEEAVRSYQKALDLDPENDSYKSNLKIAEQKLRETGTGLSF 209
Cdd:COG2956  179 RALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALEL 234
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 70-184 3.71e-17

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 76.92  E-value: 3.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  70 DILPLENLVPEDVGKADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAID 149
Cdd:COG5010   39 EDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALS 118

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 513002865 150 SKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDP 184
Cdd:COG5010  119 PDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
92-202 6.22e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 6.22e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                         90       100       110
                 ....*....|....*....|....*....|.
gi 513002865 172 AVRSYQKALDLDPENDSYKSNLKIAEQKLRE 202
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAAA 193
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
95-185 1.86e-15

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 70.58  E-value: 1.86e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  95 HMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKdCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVR 174
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|.
gi 513002865 175 SYQKALDLDPE 185
Cdd:COG3063   81 YLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 92-186 1.49e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.45  E-value: 1.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG4783   45 GEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE 124

                         90
                 ....*....|....*
gi 513002865 172 AVRSYQKALDLDPEN 186
Cdd:COG4783  125 AIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 103-193 5.16e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 67.72  E-value: 5.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865 103 AAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDL 182
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90
                 ....*....|.
gi 513002865 183 DPENDSYKSNL 193
Cdd:COG4235   81 DPDNPEALYLL 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 92-199 1.19e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 1.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                         90       100
                 ....*....|....*....|....*...
gi 513002865 172 AVRSYQKALDLDPENDSYKSNLKIAEQK 199
Cdd:COG2956  231 ALELLRKALELDPSDDLLLALADLLERK 258
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 85-202 5.80e-12

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 65.78  E-value: 5.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNnAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPD-PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYD 205

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 513002865  165 AMNKFEEAVRSYQKALDLDPENDSYKSNL------KIAEQKLRE 202
Cdd:TIGR00990 206 GLGKYADALLDLTASCIIDGFRNEQSAQAverllkKFAESKAKE 249
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 91-199 6.37e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.75  E-value: 6.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  91 EGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFE 170
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90       100       110
                 ....*....|....*....|....*....|
gi 513002865 171 EAVRSYQKALDLDPENDSYKSNL-KIAEQK 199
Cdd:COG2956   94 RAEELLEKLLELDPDDAEALRLLaEIYEQE 123
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-229 9.14e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 9.14e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  74 LENLVPEDVGKADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYS 153
Cdd:COG2956   65 HQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 513002865 154 KAYGRMGLALTAMNKFEEAVRSYQKALDLDPENDSYKSNLKIAEQKLRETGTGLSFDMASLINNPAFISMAASLMQ 229
Cdd:COG2956  145 HAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
84-187 2.23e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 62.24  E-value: 2.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  84 KADQLKDEGNNHMKEENYVAAVDCYTQA--------IELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKA 155
Cdd:COG4785   30 LFAAVLALAIALADLALALAAAALAAAAlaaeridrALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEA 109

                         90       100       110
                 ....*....|....*....|....*....|..
gi 513002865 156 YGRMGLALTAMNKFEEAVRSYQKALDLDPEND 187
Cdd:COG4785  110 YNNRGLAYLLLGDYDAALEDFDRALELDPDYA 141
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 85-193 2.00e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 2.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 164
Cdd:COG3914   44 ALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLL 123

                         90       100
                 ....*....|....*....|....*....
gi 513002865 165 AMNKFEEAVRSYQKALDLDPENDSYKSNL 193
Cdd:COG3914  124 ALGRLEEALAALRRALALNPDFAEAYLNL 152
SGTA_dimer pfam16546
Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA ...
 5-64 2.27e-10

Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerization domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerization domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.


Pssm-ID: 465168  Cd Length: 64  Bit Score: 55.60  E-value: 2.27e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 513002865    5 KHLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISLEDTHLAV----SQPLTEMFTN 64
Cdd:pfam16546   1 KRLALSIIDFLSTSLSDGTLSEDDAESLEVAIQCIAEAFEVDPDDEAAVVkafgGQSLLEIFEV 64
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 95-202 8.96e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.51  E-value: 8.96e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  95 HMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVR 174
Cdd:COG5010   30 ALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKE 109

                         90       100
                 ....*....|....*....|....*...
gi 513002865 175 SYQKALDLDPENDSYKSNLKIAEQKLRE 202
Cdd:COG5010  110 YYEKALALSPDNPNAYSNLAALLLSLGQ 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-199 2.22e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.05  E-value: 2.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  74 LENLVPEDVGKADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYS 153
Cdd:COG2956   31 LEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDA 110

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 513002865 154 KAYGRMGLALTAMNKFEEAVRSYQKALDLDPENDSYKSNL-KIAEQK 199
Cdd:COG2956  111 EALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELaELYLEQ 157
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
128-203 1.01e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.71  E-value: 1.01e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 513002865 128 AQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRsYQKALDLDPENDSYKSNLKIAEQKLRET 203
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDY 75
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 59-186 3.96e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 54.22  E-value: 3.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   59 TEMFTNSFCKNDILPLENLVPEDVGKADQLKdegNNHMKeenyvaAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDA 138
Cdd:TIGR00990 314 ARAFEKALDLGKLGEKEAIALNLRGTFKCLK---GKHLE------ALADLSKSIELDPRVTQSYIKRASMNLELGDPDKA 384

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 513002865  139 IKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEN 186
Cdd:TIGR00990 385 EEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDF 432
TPR_1 pfam00515
Tetratricopeptide repeat;
153-186 1.83e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 46.65  E-value: 1.83e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 513002865  153 SKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEN 186
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
92-183 2.40e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.78  E-value: 2.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:COG0457  117 GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVL 196

                         90
                 ....*....|..
gi 513002865 172 AVRSYQKALDLD 183
Cdd:COG0457  197 LALLLALEQALR 208
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 153-186 8.93e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.74  E-value: 8.93e-07
                           10        20        30
                   ....*....|....*....|....*....|....
gi 513002865   153 SKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEN 186
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 94-202 1.18e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.52  E-value: 1.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  94 NHMKEENYVAAVDCYTQAIELDPN-----NAVYYcnRAAAQSKLSHYTDAIKDCEKAIAI---DSKYSKAYGRMGLALTA 165
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRYPNsplapDALYW--LGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLE 79

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 513002865 166 MNKFEEAVRSYQKALDLDPENDSYksnlKIAEQKLRE 202
Cdd:COG1729   80 LGDYDKARATLEELIKKYPDSEAA----KEARARLAR 112
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 80-186 2.82e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 2.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   80 EDVGKADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRM 159
Cdd:TIGR02917 188 ADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLK 267

                          90       100
                  ....*....|....*....|....*..
gi 513002865  160 GLALTAMNKFEEAVRSYQKALDLDPEN 186
Cdd:TIGR02917 268 ALVDFQKKNYEDARETLQDALKSAPEY 294
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 128-187 9.64e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.47  E-value: 9.64e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 513002865 128 AQSKL--SHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEND 187
Cdd:cd24142    7 AEELLdqGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGG 68
TPR_11 pfam13414
TPR repeat;
160-200 1.75e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 41.30  E-value: 1.75e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 513002865  160 GLALTAMNKFEEAVRSYQKALDLDPENDSYKSNLKIAEQKL 200
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TPR_11 pfam13414
TPR repeat;
92-132 2.40e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.92  E-value: 2.40e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 513002865   92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKL 132
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 92-202 2.55e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 2.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   92 GNNHMKEENYVAAVDCYTQAIELDPNNAvyYCNRAAAQSKLSH--YTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKF 169
Cdd:TIGR02917 132 GLAYLGLGQLELAQKSYEQALAIDPRSL--YAKLGLAQLALAEnrFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNI 209

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 513002865  170 EEAVRSYQKALDLDPENDSY---KSNLKIAEQKLRE 202
Cdd:TIGR02917 210 ELALAAYRKAIALRPNNIAVllaLATILIEAGEFEE 245
TPR_1 pfam00515
Tetratricopeptide repeat;
119-152 5.64e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 5.64e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 513002865  119 AVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKY 152
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_17 pfam13431
Tetratricopeptide repeat;
107-140 6.18e-05

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 39.45  E-value: 6.18e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 513002865  107 CYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIK 140
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 37-187 6.84e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.20  E-value: 6.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   37 QCLETVFKISLEDthLAVSQPLTEMFTNSFCKNDILPLENLVP----EDVGKADQLKDE--------GNNHMKEENYVAA 104
Cdd:TIGR00990 341 KCLKGKHLEALAD--LSKSIELDPRVTQSYIKRASMNLELGDPdkaeEDFDKALKLNSEdpdiyyhrAQLHFIKGEFAQA 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  105 VDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDP 184
Cdd:TIGR00990 419 GKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEK 498


                  ...
gi 513002865  185 END 187
Cdd:TIGR00990 499 ETK 501
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 154-185 9.87e-05

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 38.66  E-value: 9.87e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 513002865  154 KAYGRMGLALTAMNKFEEAVRSYQKALDLDPE 185
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
85-118 1.10e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 1.10e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 513002865   85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNN 118
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 119-152 2.56e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 2.56e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 513002865   119 AVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKY 152
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 85-118 3.31e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 3.31e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 513002865    85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPNN 118
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_12 pfam13424
Tetratricopeptide repeat;
122-185 4.58e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 4.58e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 513002865  122 YCNRAAAQSKLSHYTDAIKDCEKAIAIDSKY--------SKAYGRMGLALTAMNKFEEAVRSYQKALDLDPE 185
Cdd:pfam13424   6 LNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhpltATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 91-200 4.68e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 4.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   91 EGNNHMKEENYVAAVDCYTQAIELDPN--NAVYYcnrAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNK 168
Cdd:TIGR02917 709 EGDLYLRQKDYPAAIQAYRKALKRAPSsqNAIKL---HRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKD 785

                          90       100       110
                  ....*....|....*....|....*....|..
gi 513002865  169 FEEAVRSYQKALDLDPENDSYKSNLKIAEQKL 200
Cdd:TIGR02917 786 YDKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL 817
TPR_8 pfam13181
Tetratricopeptide repeat;
154-185 6.70e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.61  E-value: 6.70e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 513002865  154 KAYGRMGLALTAMNKFEEAVRSYQKALDLDPE 185
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 92-177 6.71e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 6.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   92 GNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 171
Cdd:TIGR02917 608 GRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTES 687


                  ....*.
gi 513002865  172 AVRSYQ 177
Cdd:TIGR02917 688 AKKIAK 693
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 103-193 1.05e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865 103 AAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDL 182
Cdd:COG5010    4 LEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL 83

                         90
                 ....*....|.
gi 513002865 183 DPENDSYKSNL 193
Cdd:COG5010   84 DPNNPELYYNL 94
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 85-117 2.04e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.19  E-value: 2.04e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 513002865   85 ADQLKDEGNNHMKEENYVAAVDCYTQAIELDPN 117
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 96-201 3.97e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 3.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865   96 MKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRS 175
Cdd:TIGR02917 340 LRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIAD 419

                          90       100
                  ....*....|....*....|....*.
gi 513002865  176 YQKALDLDPenDSYKSNLKIAEQKLR 201
Cdd:TIGR02917 420 LETAAQLDP--ELGRADLLLILSYLR 443
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 138-191 4.49e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 38.53  E-value: 4.49e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 513002865  138 AIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDPenDSYKS 191
Cdd:PRK11447  288 AIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDP--HSSNR 339
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 86-182 5.48e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 37.99  E-value: 5.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513002865  86 DQLKDEGNNHMKEENYVAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAID-----SKYskaygrMG 160
Cdd:cd24142    1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDpdggyEKY------LY 74

                         90       100
                 ....*....|....*....|....
gi 513002865 161 LA--LTAmnkfEEAVRSYQKALDL 182
Cdd:cd24142   75 LGqlSGG----EEALQYYEKGIEI 94
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 116-187 8.22e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 37.76  E-value: 8.22e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 513002865  116 PNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDPEND 187
Cdd:TIGR02917 598 PDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNT 669
TPR_19 pfam14559
Tetratricopeptide repeat;
135-191 9.60e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 34.10  E-value: 9.60e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 513002865  135 YTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVRSYQKALDLDPENDSYKS 191
Cdd:pfam14559   4 YAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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