|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
20-223 |
6.56e-36 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 132.75 E-value: 6.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 20 YLLEDLEEMPVDKMVDLSGRQlrrlplHICSFRELVKLYLSNNNLTQLPPELEQLQNLQILALDFNNFRALPLAVCTLKQ 99
Cdd:COG4886 87 LGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTN 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 100 LCILYLGNNKLCSLPLELRLLQNLRTLWIESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGLCELRSIWLSGNLL 179
Cdd:COG4886 161 LKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2024345290 180 AEFPSvLLHMPSLEVIDVDRNAIRYFPSLAHLASLKLVIYDHNP 223
Cdd:COG4886 241 TDLPE-LGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQ 283
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
36-264 |
2.74e-14 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 72.81 E-value: 2.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 36 LSGRQLRRLPLHICSfrELVKLYLSNNNLTQLPPELEQlqNLQILALDFNNFRALPLAVCTLKQLCILYlgNNKLC---- 111
Cdd:PRK15370 206 LDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLPD--TIQEMELSINRITELPERLPSALQSLDLF--HNKISclpe 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 112 SLPLELRLL----QNLRTL-----------WIESNCLQQLPEVVCelSLLKTLHAGSNALRTLPTRLRGlcELRSIWLSG 176
Cdd:PRK15370 280 NLPEELRYLsvydNSIRTLpahlpsgithlNVQSNSLTALPETLP--PGLKTLEAGENALTSLPASLPP--ELQVLDVSK 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 177 NLLAEFPSVLlhMPSLEVIDVDRNAIRYFPSlaHL-ASLKLVIYDHNPCRNAPKVAKGVRrvgrwsEESPEPRKrsgAVI 255
Cdd:PRK15370 356 NQITVLPETL--PPTITTLDVSRNALTNLPE--NLpAALQIMQASRNNLVRLPESLPHFR------GEGPQPTR---IIV 422
|
250
....*....|
gi 2024345290 256 EIS-LSERPL 264
Cdd:PRK15370 423 EYNpFSERTI 432
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
36-202 |
3.82e-12 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 64.04 E-value: 3.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 36 LSGRQLRRLP-LHICsfRELVKLYLSNNNLTQLPPeLEQLQNLQILALDFNNFRAL-PLAvcTLKQLCILYLGNNKLCSl 113
Cdd:cd21340 9 LNDKNITKIDnLSLC--KNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKIeNLE--NLVNLKKLYLGGNRISV- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 114 pLE-LRLLQNLRTLWIESnclQQLPEVVCELSLLKTLHAGSNALRTL---------PTRLRGLCELRSIWLSGNLLAEFP 183
Cdd:cd21340 83 -VEgLENLTNLEELHIEN---QRLPPGEKLTFDPRSLAALSNSLRVLnisgnnidsLEPLAPLRNLEQLDASNNQISDLE 158
|
170 180
....*....|....*....|..
gi 2024345290 184 SV---LLHMPSLEVIDVDRNAI 202
Cdd:cd21340 159 ELldlLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
52-110 |
1.50e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 1.50e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024345290 52 RELVKLYLSNNNLTQLPPE-LEQLQNLQILALDFNNFRALPLAVCT-LKQLCILYLGNNKL 110
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLSPGAFSgLPSLRYLDLSGNRL 61
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
20-223 |
6.56e-36 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 132.75 E-value: 6.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 20 YLLEDLEEMPVDKMVDLSGRQlrrlplHICSFRELVKLYLSNNNLTQLPPELEQLQNLQILALDFNNFRALPLAVCTLKQ 99
Cdd:COG4886 87 LGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTN 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 100 LCILYLGNNKLCSLPLELRLLQNLRTLWIESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGLCELRSIWLSGNLL 179
Cdd:COG4886 161 LKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2024345290 180 AEFPSvLLHMPSLEVIDVDRNAIRYFPSLAHLASLKLVIYDHNP 223
Cdd:COG4886 241 TDLPE-LGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQ 283
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
48-232 |
1.30e-29 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 115.80 E-value: 1.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 48 ICSFRELVKLYLSNNNltqlppELEQLQNLQILALDFNNFRALPLAVCTLKQLCILYLGNNKLCSLPLELRLLQNLRTLW 127
Cdd:COG4886 92 LGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLD 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 128 IESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGLCELRSIWLSGNLLAEFPSVLLHMPSLEVIDVDRNAIRYFPS 207
Cdd:COG4886 166 LSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE 245
|
170 180
....*....|....*....|....*
gi 2024345290 208 LAHLASLKLVIYDHNPCRNAPKVAK 232
Cdd:COG4886 246 LGNLTNLEELDLSNNQLTDLPPLAN 270
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
44-229 |
1.57e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 73.04 E-value: 1.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 44 LPLHICSFRELVKLYLSNNNLTQLPPELEQLQNLQILALDFNNFRALPLAVCTLKQLCILYLGNNKlcslplELRLLQNL 123
Cdd:COG4886 42 LLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNL 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 124 RTLWIESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGLCELRSIWLSGNLLAEFPSVLLHMPSLEVIDVDRNAIR 203
Cdd:COG4886 116 ESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQIT 195
|
170 180
....*....|....*....|....*..
gi 2024345290 204 YFP-SLAHLASLKLVIYDHNPCRNAPK 229
Cdd:COG4886 196 DLPePLGNLTNLEELDLSGNQLTDLPE 222
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
36-264 |
2.74e-14 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 72.81 E-value: 2.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 36 LSGRQLRRLPLHICSfrELVKLYLSNNNLTQLPPELEQlqNLQILALDFNNFRALPLAVCTLKQLCILYlgNNKLC---- 111
Cdd:PRK15370 206 LDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLPD--TIQEMELSINRITELPERLPSALQSLDLF--HNKISclpe 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 112 SLPLELRLL----QNLRTL-----------WIESNCLQQLPEVVCelSLLKTLHAGSNALRTLPTRLRGlcELRSIWLSG 176
Cdd:PRK15370 280 NLPEELRYLsvydNSIRTLpahlpsgithlNVQSNSLTALPETLP--PGLKTLEAGENALTSLPASLPP--ELQVLDVSK 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 177 NLLAEFPSVLlhMPSLEVIDVDRNAIRYFPSlaHL-ASLKLVIYDHNPCRNAPKVAKGVRrvgrwsEESPEPRKrsgAVI 255
Cdd:PRK15370 356 NQITVLPETL--PPTITTLDVSRNALTNLPE--NLpAALQIMQASRNNLVRLPESLPHFR------GEGPQPTR---IIV 422
|
250
....*....|
gi 2024345290 256 EIS-LSERPL 264
Cdd:PRK15370 423 EYNpFSERTI 432
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
44-200 |
1.85e-12 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 67.18 E-value: 1.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 44 LPLHICSFRELVKLYLSNNNLTQLPPEL-EQLQNLQILALDFNNFRA-LPLAVCTLKQLCILYLGNNKLC-SLPLELRLL 120
Cdd:PLN00113 276 IPPSIFSLQKLISLDLSDNSLSGEIPELvIQLQNLEILHLFSNNFTGkIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKH 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 121 QNLRTLWIESNCLQ-QLPEVVCELSLLKTLHAGSNALRT-LPTRLRGLCELRSIWL-----SGNLLAEFPSVLL------ 187
Cdd:PLN00113 356 NNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGACRSLRRVRLqdnsfSGELPSEFTKLPLvyfldi 435
|
170 180
....*....|....*....|....*..
gi 2024345290 188 --------------HMPSLEVIDVDRN 200
Cdd:PLN00113 436 snnnlqgrinsrkwDMPSLQMLSLARN 462
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
36-202 |
3.82e-12 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 64.04 E-value: 3.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 36 LSGRQLRRLP-LHICsfRELVKLYLSNNNLTQLPPeLEQLQNLQILALDFNNFRAL-PLAvcTLKQLCILYLGNNKLCSl 113
Cdd:cd21340 9 LNDKNITKIDnLSLC--KNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKIeNLE--NLVNLKKLYLGGNRISV- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 114 pLE-LRLLQNLRTLWIESnclQQLPEVVCELSLLKTLHAGSNALRTL---------PTRLRGLCELRSIWLSGNLLAEFP 183
Cdd:cd21340 83 -VEgLENLTNLEELHIEN---QRLPPGEKLTFDPRSLAALSNSLRVLnisgnnidsLEPLAPLRNLEQLDASNNQISDLE 158
|
170 180
....*....|....*....|..
gi 2024345290 184 SV---LLHMPSLEVIDVDRNAI 202
Cdd:cd21340 159 ELldlLSSWPSLRELDLTGNPV 180
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
12-202 |
4.77e-09 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 56.71 E-value: 4.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 12 VPSDECQKYLL-EDLEEMPVD----KMVDLSGRQLRRLPlhiCSFRELVKLYLSNNNLTQLPPELEQLQNLQILALDFNN 86
Cdd:PRK15387 280 LPSGLCKLWIFgNQLTSLPVLppglQELSVSDNQLASLP---ALPSELCKLWAYNNQLTSLPTLPSGLQELSVSDNQLAS 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 87 FRALPlavctlKQLCILYLGNNKLCSLPlelRLLQNLRTLWIESNCLQQLPEVVCElslLKTLHAGSNALRTLPTRLRGL 166
Cdd:PRK15387 357 LPTLP------SELYKLWAYNNRLTSLP---ALPSGLKELIVSGNRLTSLPVLPSE---LKELMVSGNRLTSLPMLPSGL 424
|
170 180 190
....*....|....*....|....*....|....*.
gi 2024345290 167 CELRsiwLSGNLLAEFPSVLLHMPSLEVIDVDRNAI 202
Cdd:PRK15387 425 LSLS---VYRNQLTRLPESLIHLSSETTVNLEGNPL 457
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
32-202 |
6.95e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 56.39 E-value: 6.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 32 KMVDLSGRQLR-RLPLHICSFRELVKLYLSNNNLT-QLPPELEQLQNLQILALDFNNFRA-------------------- 89
Cdd:PLN00113 167 KVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGYNNLSGeipyeiggltslnhldlvyn 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 90 -----LPLAVCTLKQLCILYLGNNKLC-SLPLELRLLQNLRTLWIESNCLQ-QLPEVVCELSLLKTLHAGSNALR-TLPT 161
Cdd:PLN00113 247 nltgpIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQLQNLEILHLFSNNFTgKIPV 326
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2024345290 162 RLRGLCELRSIWL-SGNLLAEFPSVLLHMPSLEVIDVDRNAI 202
Cdd:PLN00113 327 ALTSLPRLQVLQLwSNKFSGEIPKNLGKHNNLTVLDLSTNNL 368
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
53-223 |
1.13e-07 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 52.86 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 53 ELVKLYLSNNNLTQLPPELEQLQNLQILALDFNNFRALPLAVCTL----------------------------------K 98
Cdd:PRK15387 243 ELRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTHLPALPSGLCKLwifgnqltslpvlppglqelsvsdnqlaslpalpS 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 99 QLCILYLGNNKLCSLPlelRLLQNLRTLWIESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGL------------ 166
Cdd:PRK15387 323 ELCKLWAYNNQLTSLP---TLPSGLQELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSGLKELivsgnrltslpv 399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 167 --CELRSIWLSGNLLAEFPSVLLHMPSLEVIdvdRNAIRYFP-SLAHLASLKLVIYDHNP 223
Cdd:PRK15387 400 lpSELKELMVSGNRLTSLPMLPSGLLSLSVY---RNQLTRLPeSLIHLSSETTVNLEGNP 456
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
35-217 |
2.38e-06 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 48.39 E-value: 2.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 35 DLSGRQLRRLPlHICSFRELVKLYLSNNNLTQLPPELeQLQNLQILALDFNNFRALPLAVCTLKQLCILYLGNNKLCSLP 114
Cdd:COG4886 234 DLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLA-NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 115 LELRLLQNLRTLWIESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGLCELRSIWLSGNLLAEFPSVLLHMPSLEV 194
Cdd:COG4886 312 ELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLL 391
|
170 180
....*....|....*....|...
gi 2024345290 195 IDVDRNAIRYFPSLAHLASLKLV 217
Cdd:COG4886 392 LLLTTTAGVLLLTLALLDAVNTE 414
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
36-196 |
4.45e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 46.70 E-value: 4.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 36 LSGRQLRRLPlHICSFRELVKLYLSNNNLTQLppE-LEQLQNLQIL-----------ALDFNNFRALPLAVCtlkqLCIL 103
Cdd:cd21340 53 LQNNQIEKIE-NLENLVNLKKLYLGGNRISVV--EgLENLTNLEELhienqrlppgeKLTFDPRSLAALSNS----LRVL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 104 YLGNNKLCSLpLELRLLQNLRTLWIESNCLQQLpEVVCELsllktlhagsnalrtlptrLRGLCELRSIWLSGNLLAEFP 183
Cdd:cd21340 126 NISGNNIDSL-EPLAPLRNLEQLDASNNQISDL-EELLDL-------------------LSSWPSLRELDLTGNPVCKKP 184
|
170
....*....|....*..
gi 2024345290 184 ----SVLLHMPSLEVID 196
Cdd:cd21340 185 kyrdKIILASKSLEVLD 201
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
95-208 |
2.68e-05 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 45.54 E-value: 2.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 95 CTLKQLCILYLGNNKLCSLPlelRLLQNLRTLWIESNCLQQLPEV---VCELSLLktlhagSNALRTLPTRLRGLCELrs 171
Cdd:PRK15387 219 CLPAHITTLVIPDNNLTSLP---ALPPELRTLEVSGNQLTSLPVLppgLLELSIF------SNPLTHLPALPSGLCKL-- 287
|
90 100 110
....*....|....*....|....*....|....*..
gi 2024345290 172 iWLSGNLLAEFPSVllhMPSLEVIDVDRNAIRYFPSL 208
Cdd:PRK15387 288 -WIFGNQLTSLPVL---PPGLQELSVSDNQLASLPAL 320
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
52-110 |
1.50e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 1.50e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024345290 52 RELVKLYLSNNNLTQLPPE-LEQLQNLQILALDFNNFRALPLAVCT-LKQLCILYLGNNKL 110
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLSPGAFSgLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
19-213 |
5.21e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.80 E-value: 5.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 19 KYLLEDLEEMPVDKMVDLSGRQLRRLP--LHIC-----SFRELVKLYLSNNNLTQLPPE----LEQLQNLQILALDFNNF 87
Cdd:cd00116 41 KALASALRPQPSLKELCLSLNETGRIPrgLQSLlqgltKGCGLQELDLSDNALGPDGCGvlesLLRSSSLQELKLNNNGL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 88 --RALPLAVCTLKQ----LCILYLGNNKLcslplelrllqnlrtlwiESNCLQQLPEVVCELSLLKTLHAGSNAL----- 156
Cdd:cd00116 121 gdRGLRLLAKGLKDlppaLEKLVLGRNRL------------------EGASCEALAKALRANRDLKELNLANNGIgdagi 182
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024345290 157 RTLPTRLRGLCELRSIWLSGNLLAE-----FPSVLLHMPSLEVIDVDRNAIRYFPsLAHLAS 213
Cdd:cd00116 183 RALAEGLKANCNLEVLDLNNNGLTDegasaLAETLASLKSLEVLNLGDNNLTDAG-AAALAS 243
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
18-200 |
8.47e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.03 E-value: 8.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 18 QKYLLE--DLEEMPVDKM-VDLSGRQLRRLPLHICsfrelvKLYLSNNNLT-----QLPPELEQLQNLQILALDFNNFRA 89
Cdd:cd00116 106 RSSSLQelKLNNNGLGDRgLRLLAKGLKDLPPALE------KLVLGRNRLEgasceALAKALRANRDLKELNLANNGIGD 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 90 LPLAvctlkqlcilylgnnklcSLPLELRLLQNLRTLWIESNCL-----QQLPEVVCELSLLKTLHAGSNALRTLPTR-- 162
Cdd:cd00116 180 AGIR------------------ALAEGLKANCNLEVLDLNNNGLtdegaSALAETLASLKSLEVLNLGDNNLTDAGAAal 241
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2024345290 163 ----LRGLCELRSIWLSGNLLAE-----FPSVLLHMPSLEVIDVDRN 200
Cdd:cd00116 242 asalLSPNISLLTLSLSCNDITDdgakdLAEVLAEKESLLELDLRGN 288
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
33-200 |
4.89e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 38.29 E-value: 4.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 33 MVDLSGRQLR-RLPLHICSFRELVKLYLSNNNL-TQLPPELEQLQNLQILALDFNNFRA-LPLAVCTLKQLCILYLGNNK 109
Cdd:PLN00113 360 VLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDNSFSGeLPSEFTKLPLVYFLDISNNN 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024345290 110 LC----SLPLELRLLQNLRTlwIESNCLQQLPEVVCElSLLKTLHAGSNALR-TLPTRLRGLCELRSIWLSGNLLA-EFP 183
Cdd:PLN00113 440 LQgrinSRKWDMPSLQMLSL--ARNKFFGGLPDSFGS-KRLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKLSgEIP 516
|
170
....*....|....*..
gi 2024345290 184 SVLLHMPSLEVIDVDRN 200
Cdd:PLN00113 517 DELSSCKKLVSLDLSHN 533
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
54-86 |
5.81e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 34.14 E-value: 5.81e-03
10 20 30
....*....|....*....|....*....|...
gi 2024345290 54 LVKLYLSNNNLTQLPPeLEQLQNLQILALDFNN 86
Cdd:pfam12799 3 LEVLDLSNNQITDIPP-LAKLPNLETLDLSGNN 34
|
|
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