|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
28-674 |
1.08e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 76.63 E-value: 1.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 28 SQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEF---EKGEAIRQSLEYALAIAKKDARL 104
Cdd:TIGR02168 223 RELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVselEEEIEELQKELYALANEISRLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 105 TVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDIlrthkdeyELLLKERGELESIL 184
Cdd:TIGR02168 303 QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL--------EELEAELEELESRL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 185 QKQNSALQNLSKKMKDMELEhrdcsdlltrqvhkLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAhlKSKFNLEIT 264
Cdd:TIGR02168 375 EELEEQLETLRSKVAQLELQ--------------IASLNNEIERLEARLERLEDRRERLQQEIEELLKK--LEEAELKEL 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 265 QMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENA---YEREKQKAQENLEKVNRLEREY------ISTNKQMNEKI 335
Cdd:TIGR02168 439 QAELEELEEELEELQEELERLEEALEELREELEEAEQAldaAERELAQLQARLDSLERLQENLegfsegVKALLKNQSGL 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 336 EEKKEIIKD---------------LSERLQ----ENEKIHRELQDKLATAKKHQVFVtetyennmielkLLLDSFAMSGQ 396
Cdd:TIGR02168 519 SGILGVLSElisvdegyeaaieaaLGGRLQavvvENLNAAKKAIAFLKQNELGRVTF------------LPLDSIKGTEI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 397 RTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLE------------DTSNELKK--------------------------- 437
Cdd:TIGR02168 587 QGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddlDNALELAKklrpgyrivtldgdlvrpggvitggsa 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 438 ---MNALC-----ENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEK 509
Cdd:TIGR02168 667 ktnSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 510 VRAAESENEIQKLTraykKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFswSELCAVLQENVDALILDLNRANEKIS 589
Cdd:TIGR02168 747 ERIAQLSKELTELE----AEIEELEERLEEAEEELAEAEAEIEELEAQIEQL--KEELKALREALDELRAELTLLNEEAA 820
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 590 HLEYICKSKSDTMKELQRSQED----------DMSKMAEQM-KAQESC---------WQKQKKYLEQQYSDLLGEVHARA 649
Cdd:TIGR02168 821 NLRERLESLERRIAATERRLEDleeqieelseDIESLAAEIeELEELIeeleseleaLLNERASLEEALALLRSELEELS 900
|
730 740
....*....|....*....|....*
gi 2024433729 650 QEYKETAEKNKEKICVLEKRQEELA 674
Cdd:TIGR02168 901 EELRELESKRSELRRELEELREKLA 925
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
43-367 |
3.82e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 71.64 E-value: 3.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 43 EDLKRKLCQAKE--EKVDIIIKhnqELRDyeiQIVKLRSEFEKGE---AIRQSLE----YALAIAKKDARLTVRTVEEEL 113
Cdd:TIGR02169 173 EKALEELEEVEEniERLDLIID---EKRQ---QLERLRREREKAEryqALLKEKReyegYELLKEKEALERQKEAIERQL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 114 SDARNKLAELQVFNEKLQQRLVETEktfhiaqqkwkeqqQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQN 193
Cdd:TIGR02169 247 ASLEEELEKLTEEISELEKRLEEIE--------------QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 194 LSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIK--------------QLEENFEAERAAHLKSKF 259
Cdd:TIGR02169 313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAelkeeledlraeleEVDKEFAETRDELKDYRE 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 260 NLEITQMRIRELEGA---LQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKvnrLEREYISTNKQMNEKIE 336
Cdd:TIGR02169 393 KLEKLKREINELKREldrLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK---QEWKLEQLAADLSKYEQ 469
|
330 340 350
....*....|....*....|....*....|.
gi 2024433729 337 EKKEIIKDLSERLQENEKIHRELQDKLATAK 367
Cdd:TIGR02169 470 ELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
40-676 |
2.94e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.54 E-value: 2.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 40 DVAEDLKRKL--CQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEY-ALAIAKKDARLTVRTVEEELSDA 116
Cdd:TIGR02168 193 DILNELERQLksLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELkEAEEELEELTAELQELEEKLEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 117 RNKLAELQVFNEKLQQRL---------VETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQ 187
Cdd:TIGR02168 273 RLEVSELEEEIEELQKELyalaneisrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 188 ----NSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLE---ENFEAERAAHLKSKFN 260
Cdd:TIGR02168 353 leslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEdrrERLQQEIEELLKKLEE 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 261 LEI--TQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENA---YEREKQKAQENLEKVNRLEREY------ISTNK 329
Cdd:TIGR02168 433 AELkeLQAELEELEEELEELQEELERLEEALEELREELEEAEQAldaAERELAQLQARLDSLERLQENLegfsegVKALL 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 330 QMNEKIEEKKEIIKD---------------LSERLQ----ENEKIHRELQDKLATAKKHQVFVtetyennmielkLLLDS 390
Cdd:TIGR02168 513 KNQSGLSGILGVLSElisvdegyeaaieaaLGGRLQavvvENLNAAKKAIAFLKQNELGRVTF------------LPLDS 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 391 FAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLE------------DTSNEL-KKMNALCENTTKELEISRdKMC 457
Cdd:TIGR02168 581 IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddlDNALELaKKLRPGYRIVTLDGDLVR-PGG 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 458 VLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQnvqqrweeekvRAAESENEIQKLTRAYKKDMEEKLTFL 537
Cdd:TIGR02168 660 VITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-----------ELRKELEELEEELEQLRKELEELSRQI 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 538 HGLYQHLVAGCVLIKQpegildrfsWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMskma 617
Cdd:TIGR02168 729 SALRKDLARLEAEVEQ---------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK---- 795
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024433729 618 EQMKAQEScwqkQKKYLEQQYSDLLGEVHA---RAQEYKETAEKNKEKICVLEKRQEELALE 676
Cdd:TIGR02168 796 EELKALRE----ALDELRAELTLLNEEAANlreRLESLERRIAATERRLEDLEEQIEELSED 853
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
421-1127 |
4.81e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.77 E-value: 4.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 421 LTAYQNKLEDTSNELKKMNALCENTTKELEisrdkmcVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQN 500
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQ-------ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 501 VQQRWEEEKVRAAESENEIQKLTRAyKKDMEEKLTflhglyqhlvagcvlikqpegildrfSWSELCAVLQENVDALILD 580
Cdd:TIGR02168 307 LRERLANLERQLEELEAQLEELESK-LDELAEELA--------------------------ELEEKLEELKEELESLEAE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 581 LNRANEKISHLEyickSKSDTMKELQRSQEDDMSKMAEQMKAQescwQKQKKYLEQQYSDLlgevharaqeyKETAEKNK 660
Cdd:TIGR02168 360 LEELEAELEELE----SRLEELEEQLETLRSKVAQLELQIASL----NNEIERLEARLERL-----------EDRRERLQ 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 661 EKICVLEKRQEELALENlyVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNiyeLVNQEIRTLV 740
Cdd:TIGR02168 421 QEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA---QLQARLDSLE 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 741 HILSGVEEEKEDDAKIKKHKFRG---------LIHV---FRRGVIAVLAANRLKVLAQSSSSLFSLINGFKE--GIGILV 806
Cdd:TIGR02168 496 RLQENLEGFSEGVKALLKNQSGLsgilgvlseLISVdegYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQneLGRVTF 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 807 CVGDSKgKHNMSRYNKEgircvEALNWFTSP-DLLTAVISSVTELQDVISKtdpkscLSGRLLVS---AARNSFSKLMDK 882
Cdd:TIGR02168 576 LPLDSI-KGTEIQGNDR-----EILKNIEGFlGVAKDLVKFDPKLRKALSY------LLGGVLVVddlDNALELAKKLRP 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 883 LNVImesVPLDSsrsvtyveknsliqrlahglHRINARALEAGSCDRRpiMKSIASLQKQIAEFTQRLHTVEVERCSLRR 962
Cdd:TIGR02168 644 GYRI---VTLDG--------------------DLVRPGGVITGGSAKT--NSSILERRREIEELEEKIEELEEKIAELEK 698
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 963 ELAEFKLNFSKMKQEADKAQSLKE----QLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLE 1038
Cdd:TIGR02168 699 ALAELRKELEELEEELEQLRKELEelsrQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA 778
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1039 LHSSE----EADKNQVLSETV---KRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELII 1111
Cdd:TIGR02168 779 EAEAEieelEAQIEQLKEELKalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858
|
730
....*....|....*.
gi 2024433729 1112 NQMKSVEATLHTVRDQ 1127
Cdd:TIGR02168 859 AEIEELEELIEELESE 874
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
110-368 |
4.00e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.96 E-value: 4.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 110 EEELSDARNKLAELQ-VFNEkLQQRL------VETEKTFHIAQQKWKEQQQRLASEKDDILRthkDEYELLLKERGELES 182
Cdd:COG1196 178 ERKLEATEENLERLEdILGE-LERQLeplerqAEKAERYRELKEELKELEAELLLLKLRELE---AELEELEAELEELEA 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 183 ILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLE 262
Cdd:COG1196 254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 263 ITQMRIRELEGALqmekvsqAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEII 342
Cdd:COG1196 334 ELEEELEELEEEL-------EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406
|
250 260
....*....|....*....|....*.
gi 2024433729 343 KDLSERLQENEKIHRELQDKLATAKK 368
Cdd:COG1196 407 EAEEALLERLERLEEELEELEEALAE 432
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
47-390 |
5.20e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 5.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 47 RKLCQAKE--EKVDIIIkhnQELRDyeiQIVKLRSEFEKgeAiRQSLEYALAIAKKDARLTV---RTVEEELSDARNKLA 121
Cdd:COG1196 179 RKLEATEEnlERLEDIL---GELER---QLEPLERQAEK--A-ERYRELKEELKELEAELLLlklRELEAELEELEAELE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 122 ELQVFNEKLQQRLVETEKtfhiaqqKWKEQQQRLASEKDDILRTHKDEYELLlKERGELESILQKQNSALQNLSKKMKDM 201
Cdd:COG1196 250 ELEAELEELEAELAELEA-------ELEELRLELEELELELEEAQAEEYELL-AELARLEQDIARLEERRRELEERLEEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 202 ElehrdcsdlltrqvhkleysaEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVS 281
Cdd:COG1196 322 E---------------------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 282 QAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQd 361
Cdd:COG1196 381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE- 459
|
330 340
....*....|....*....|....*....
gi 2024433729 362 KLATAKKHQVFVTETYENNMIELKLLLDS 390
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAE 488
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
17-678 |
5.53e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.31 E-value: 5.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 17 EAKRLCSAKSGSQLLHNSSASELDVAE---DLKRKLCQAKEEKVDIIIK----HNQELRDYEIQIVKLRSEFEKGEaiRQ 89
Cdd:TIGR02168 240 ELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELQKelyaLANEISRLEQQKQILRERLANLE--RQ 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 90 SLEYALAIAKKDARLTvrTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDE 169
Cdd:TIGR02168 318 LEELEAQLEELESKLD--ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 170 yELLLKERGELESILQKQNSALQNLSK-----KMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLE 244
Cdd:TIGR02168 396 -ASLNNEIERLEARLERLEDRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 245 ENFEAERAAHLKSKFNLEITQMRIRELEGALQMEK--VSQAEALSDLEMIRKEFKEVENAYEREKQKA-QENLEK--VNR 319
Cdd:TIGR02168 475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKalLKNQSGLSGILGVLSELISVDEGYEAAIEAAlGGRLQAvvVEN 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 320 LE--REYISTNKQMNE--------KIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQ---------VFVTETYENN 380
Cdd:TIGR02168 555 LNaaKKAIAFLKQNELgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggVLVVDDLDNA 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 381 MIELKLLL----------DSFAMSGQRTAGTCKDKDKPSSLSV-LETLRYTLTAYQNKLEDTSNELKKMNALCENTTKEL 449
Cdd:TIGR02168 635 LELAKKLRpgyrivtldgDLVRPGGVITGGSAKTNSSILERRReIEELEEKIEELEEKIAELEKALAELRKELEELEEEL 714
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 450 EISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKD 529
Cdd:TIGR02168 715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 530 MEE-------------KLTFLHGLYQHLVAGCVLIKQpegilDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICK 596
Cdd:TIGR02168 795 KEElkalrealdelraELTLLNEEAANLRERLESLER-----RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 597 SKSDTMKELQ----------RSQEDDMSKMAEQMKAQESCWQKQKKYLEQ----------------------------QY 638
Cdd:TIGR02168 870 ELESELEALLnerasleealALLRSELEELSEELRELESKRSELRRELEElreklaqlelrleglevridnlqerlseEY 949
|
730 740 750 760
....*....|....*....|....*....|....*....|
gi 2024433729 639 SDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENL 678
Cdd:TIGR02168 950 SLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNL 989
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
43-533 |
8.75e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 63.54 E-value: 8.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 43 EDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEyALAIAKKDARLTVRTVEEELSDARNKLAE 122
Cdd:PRK03918 192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 123 ---------------------------LQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRL--ASEKDDILRTHKDEYELL 173
Cdd:PRK03918 271 lkkeieeleekvkelkelkekaeeyikLSEFYEEYLDELREIEKRLSRLEEEINGIEERIkeLEEKEERLEELKKKLKEL 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 174 LKERGELESILQKQNSA------LQNLSKKMKDMELEhrdcsdlltRQVHKLEYSAEQEERLKKELEAATDRIKQLEENF 247
Cdd:PRK03918 351 EKRLEELEERHELYEEAkakkeeLERLKKRLTGLTPE---------KLEKELEELEKAKEEIEEEISKITARIGELKKEI 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 248 EAERAAHLKSKFNLEITQMRIRELEGalQMEKVSQAEALSDLEMIRKEFKEVENAyEREKQKAQENLEKVNRLEREYIST 327
Cdd:PRK03918 422 KELKKAIEELKKAKGKCPVCGRELTE--EHRKELLEEYTAELKRIEKELKEIEEK-ERKLRKELRELEKVLKKESELIKL 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 328 NKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVT------ETYENNMIELKLLLDSFAMSGQRTAGT 401
Cdd:PRK03918 499 KELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKkeleklEELKKKLAELEKKLDELEEELAELLKE 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 402 CKDKDKPSSLSVLETLRYTLTAYQ--NKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNh 479
Cdd:PRK03918 579 LEELGFESVEELEERLKELEPFYNeyLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS- 657
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 2024433729 480 lHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLtRAYKKDMEEK 533
Cdd:PRK03918 658 -EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL-KEELEEREKA 709
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
29-321 |
1.78e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.65 E-value: 1.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 29 QLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFekgEAIRQSLEyalaiakkDARLTVRT 108
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLEL---EELELELE--------EAQAEEYE 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 109 VEEELSDARNKLAELQVFNEKLQQRLVETEKtfhiAQQKWKEQQQRLASEKDDIlrthKDEYELLLKERGELESILQKQN 188
Cdd:COG1196 293 LLAELARLEQDIARLEERRRELEERLEELEE----ELAELEEELEELEEELEEL----EEELEEAEEELEEAEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 189 SALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRI 268
Cdd:COG1196 365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 2024433729 269 RELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLE 321
Cdd:COG1196 445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
94-323 |
1.83e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.70 E-value: 1.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 94 ALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRThKDEYELL 173
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAEL-EKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 174 LKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAA 253
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 254 hlkskfnLEITQMRIRELEGALQMEKVSQAEALSDLEmirKEFKEVENAYEREKQKAQENLEKVNRLERE 323
Cdd:COG4942 176 -------LEALLAELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
45-368 |
3.38e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 61.57 E-value: 3.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 45 LKRKLCQAKEEKVDIIIKH-NQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKK---DARLTVRTVEEELSDARNKL 120
Cdd:TIGR04523 293 LKSEISDLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKeltNSESENSEKQRELEEKQNEI 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 121 AELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQrLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKD 200
Cdd:TIGR04523 373 EKLKKENQSYKQEIKNLESQINDLESKIQNQEK-LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSV 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 201 MEL---EHRDCSDLLTRQVHKLEYSAEQE----ERLKKELEAATDRIKQLEENfeaerAAHLKSKF-NLEITQMRIRELE 272
Cdd:TIGR04523 452 KELiikNLDNTRESLETQLKVLSRSINKIkqnlEQKQKELKSKEKELKKLNEE-----KKELEEKVkDLTKKISSLKEKI 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 273 GALQMEKVSQAEALSDLE--MIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQ 350
Cdd:TIGR04523 527 EKLESEKKEKESKISDLEdeLNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE 606
|
330
....*....|....*...
gi 2024433729 351 ENEKIHRELQDKLATAKK 368
Cdd:TIGR04523 607 EKEKKISSLEKELEKAKK 624
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
212-1093 |
6.15e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.23 E-value: 6.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 212 LTRQVHKLEYSAEQEER---LKKELEAA-----TDRIKQLEENFEAeraahlkskFNLEITQMRIRELEGALQMekvsqA 283
Cdd:TIGR02168 198 LERQLKSLERQAEKAERykeLKAELRELelallVLRLEELREELEE---------LQEELKEAEEELEELTAEL-----Q 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 284 EALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEiikdLSERLQENEKIHRELQDKL 363
Cdd:TIGR02168 264 ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEE----LEAQLEELESKLDELAEEL 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 364 ATAKKhqvfVTETYENNMIELKLLLDSFAmsgqrtagtckdKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCE 443
Cdd:TIGR02168 340 AELEE----KLEELKEELESLEAELEELE------------AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 444 NTTKELEISRDKMCVLSQDLKEARDKLANANKELnhLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLT 523
Cdd:TIGR02168 404 RLEARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 524 RaykkdmeekltflhglyqhlvagcvlikqpegildrfswselcavlqenvdalilDLNRANEKIshleyicksksDTMK 603
Cdd:TIGR02168 482 R-------------------------------------------------------ELAQLQARL-----------DSLE 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 604 ELQRSQEDDMSKMAEQMKaqescWQKQKKYLEQQYSDLLgEVharAQEYKETAEKnkekicVLEKRQEELALENLYVKNT 683
Cdd:TIGR02168 496 RLQENLEGFSEGVKALLK-----NQSGLSGILGVLSELI-SV---DEGYEAAIEA------ALGGRLQAVVVENLNAAKK 560
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 684 LTQIQKEHSSllaacallagalyplyGRsCAMSIQRDLLQDQVNIYEL-VNQEIRTLVHILSGVEEEKEddakikkhKFR 762
Cdd:TIGR02168 561 AIAFLKQNEL----------------GR-VTFLPLDSIKGTEIQGNDReILKNIEGFLGVAKDLVKFDP--------KLR 615
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 763 GLIHVFRRGVIAV--LA-ANRLKVLAQSSSSLFSLiNGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTS--- 836
Cdd:TIGR02168 616 KALSYLLGGVLVVddLDnALELAKKLRPGYRIVTL-DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEkia 694
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 837 --PDLLTAVISSVTELQDVISKTDpKSCLSGRLLVSAARNSFSKLMDKLNVIMESVpldSSRSVTYVEKNSLIQRLAHGL 914
Cdd:TIGR02168 695 elEKALAELRKELEELEEELEQLR-KELEELSRQISALRKDLARLEAEVEQLEERI---AQLSKELTELEAEIEELEERL 770
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 915 HRINARALEAgscdrrpiMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQeadKAQSLKEQLSLFKQS 994
Cdd:TIGR02168 771 EEAEEELAEA--------EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE---RLESLERRIAATERR 839
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 995 KLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNK-------LELHSSEEADKNQVLSETVKRLSEAKMELRR 1067
Cdd:TIGR02168 840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNErasleeaLALLRSELEELSEELRELESKRSELRRELEE 919
|
890 900
....*....|....*....|....*.
gi 2024433729 1068 KDQSLRQLNRLLTQLEQDKRRLKESI 1093
Cdd:TIGR02168 920 LREKLAQLELRLEGLEVRIDNLQERL 945
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
109-682 |
3.38e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.59 E-value: 3.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 109 VEEELSDARNKLAELQVFNEKLqqrlVETEKTFHIAQQKWKEQQQRLASE-------KDDILRTHKDEYELLLKERGELE 181
Cdd:pfam15921 108 LRQSVIDLQTKLQEMQMERDAM----ADIRRRESQSQEDLRNQLQNTVHEleaakclKEDMLEDSNTQIEQLRKMMLSHE 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 182 SILQKQNSALQNLSKKMKDMELEHRDCSDL--------LTRQVHKLEYS-----------AEQEERLKKE--------LE 234
Cdd:pfam15921 184 GVLQEIRSILVDFEEASGKKIYEHDSMSTMhfrslgsaISKILRELDTEisylkgrifpvEDQLEALKSEsqnkiellLQ 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 235 AATDRIKQLEENFE------AERAAHLKSKFN-----LEITQMRIRElEGALQMEKVSQAEalSDLEMIRKEFKEVENAY 303
Cdd:pfam15921 264 QHQDRIEQLISEHEveitglTEKASSARSQANsiqsqLEIIQEQARN-QNSMYMRQLSDLE--STVSQLRSELREAKRMY 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 304 ErekqkaqenlEKVNRLEREYISTNKQMNEKIEEKKEIIkdlserlQENEKIHRELQDKLATAKKHQVFVTETYENNmie 383
Cdd:pfam15921 341 E----------DKIEELEKQLVLANSELTEARTERDQFS-------QESGNLDDQLQKLLADLHKREKELSLEKEQN--- 400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 384 lKLLLDsfamsgqrtagtckdKDKPSSLsvletlryTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDL 463
Cdd:pfam15921 401 -KRLWD---------------RDTGNSI--------TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGK 456
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 464 KEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWE------EEKVRAAESEN-EIQKLTRAYKKDMEEkltf 536
Cdd:pfam15921 457 NESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSdltaslQEKERAIEATNaEITKLRSRVDLKLQE---- 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 537 lhglYQHLvagcvlikQPEGildrfswsELCAVLQENVDALILDLnranekishleyickSKSDTMKELQRSQEDDMSKM 616
Cdd:pfam15921 533 ----LQHL--------KNEG--------DHLRNVQTECEALKLQM---------------AEKDKVIEILRQQIENMTQL 577
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024433729 617 AEQMKAQESCWQKQKKYLEQQYSDLLGEVharaQEYKETAEKNKEKICVLEKRQEELALENLYVKN 682
Cdd:pfam15921 578 VGQHGRTAGAMQVEKAQLEKEINDRRLEL----QEFKILKDKKDAKIRELEARVSDLELEKVKLVN 639
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
38-324 |
7.44e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 57.36 E-value: 7.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 38 ELDVAEDLKRKLCQAKEEKvdiiikhNQELRDYEIQIVKLRSEFEKGEAIR---------QSLE---YALAIAKKDARlt 105
Cdd:PRK02224 406 DLGNAEDFLEELREERDEL-------REREAELEATLRTARERVEEAEALLeagkcpecgQPVEgspHVETIEEDRER-- 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 106 VRTVEEELSDARNKLAELQVFNEKLQQrLVETEKTFHIAQQKWKEQQQRLA---------SEKDDILRTHKDEYEL---- 172
Cdd:PRK02224 477 VEELEAELEDLEEEVEEVEERLERAED-LVEAEDRIERLEERREDLEELIAerretieekRERAEELRERAAELEAeaee 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 173 --------------LLKERGELESILQKQNSALQNLsKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATD 238
Cdd:PRK02224 556 kreaaaeaeeeaeeAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRE 634
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 239 RIKQLEENFEAERAAHLKSKfnLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAyeREKQKAQENleKVN 318
Cdd:PRK02224 635 RKRELEAEFDEARIEEARED--KERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEEL--RERREALEN--RVE 708
|
....*.
gi 2024433729 319 RLEREY 324
Cdd:PRK02224 709 ALEALY 714
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
43-361 |
9.28e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.00 E-value: 9.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 43 EDLKRKLCQAKEEKvdiiikhnQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEE----------- 111
Cdd:PRK03918 387 EKLEKELEELEKAK--------EEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEehrkelleeyt 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 112 -ELSDARNKLAELQVFNEKLQQRLVETEKTFH-----IAQQKWKEQQQRLASEKDDI----LRTHKDEYELLLKERGELE 181
Cdd:PRK03918 459 aELKRIEKELKEIEEKERKLRKELRELEKVLKkeselIKLKELAEQLKELEEKLKKYnleeLEKKAEEYEKLKEKLIKLK 538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 182 ---SILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEysaeqeERLKKELEAATDRIKQLEEnFEAERAAHLKSK 258
Cdd:PRK03918 539 geiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELE------ELGFESVEELEERLKELEP-FYNEYLELKDAE 611
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 259 FNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQEnlEKVNRLEREYISTN---KQMNEKI 335
Cdd:PRK03918 612 KELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELR--EEYLELSRELAGLRaelEELEKRR 689
|
330 340
....*....|....*....|....*.
gi 2024433729 336 EEKKEIIKDLSERLQENEKIHRELQD 361
Cdd:PRK03918 690 EEIKKTLEKLKEELEEREKAKKELEK 715
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
156-537 |
1.70e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 56.23 E-value: 1.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 156 ASEKDDILRTHKDEYELllkeRGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQvhklEYSAEQEERLKKELEA 235
Cdd:TIGR02169 670 RSEPAELQRLRERLEGL----KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI----EQLEQEEEKLKERLEE 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 236 ATDRIKQLEENFEAERA--AHLKSKfnLEITQMRIRELEGALqmEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQEN 313
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSelKELEAR--IEELEEDLHKLEEAL--NDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 314 LEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVtETYENNMIELKllldsfam 393
Cdd:TIGR02169 818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL-RDLESRLGDLK-------- 888
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 394 sgqrtagtcKDKDKpsslsvletLRYTLTAYQNKLEdtsnelkkmnalcenttkELEISRDKMCVLSQDLKEARDKLANA 473
Cdd:TIGR02169 889 ---------KERDE---------LEAQLRELERKIE------------------ELEAQIEKKRKRLSELKAKLEALEEE 932
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024433729 474 NKELNHLHT---ECADKAALIGTLQMELQNVQQRWE--EEKVRAAESENEIQKLTRaykKDMEEKLTFL 537
Cdd:TIGR02169 933 LSEIEDPKGedeEIPEEELSLEDVQAELQRVEEEIRalEPVNMLAIQEYEEVLKRL---DELKEKRAKL 998
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
64-323 |
2.17e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 2.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 64 NQELRDYEIQIVKLRSEFEKgeaiRQSLEYALAIAKKDArltvrtvEEELSDARNKLAELQVFNEKLQQRLVETEKTFHI 143
Cdd:TIGR02169 680 RERLEGLKRELSSLQSELRR----IENRLDELSQELSDA-------SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 144 AQQK---WKEQQQRLASEKDDILRT-HKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKL 219
Cdd:TIGR02169 749 LEQEienVKSELKELEARIEELEEDlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 220 EYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEV 299
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908
|
250 260
....*....|....*....|....
gi 2024433729 300 ENAYEREKQKAQENLEKVNRLERE 323
Cdd:TIGR02169 909 EAQIEKKRKRLSELKAKLEALEEE 932
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
46-319 |
9.03e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 9.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 46 KRKLcQAKEEKVDIIikhNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAkkDARLTVRTVEEELSDARNKLAELQV 125
Cdd:COG4913 609 RAKL-AALEAELAEL---EEELAEAEERLEALEAELDALQERREALQRLAEYS--WDEIDVASAEREIAELEAELERLDA 682
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 126 FNEKLQQrlvetektfhiAQQKWKEQQQRLasekddilRTHKDEYELLLKERGELES----ILQKQNSALQNLSKKMKDM 201
Cdd:COG4913 683 SSDDLAA-----------LEEQLEELEAEL--------EELEEELDELKGEIGRLEKeleqAEEELDELQDRLEAAEDLA 743
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 202 ELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHlKSKFNLEITQMRIrELEGALQMEKVS 281
Cdd:COG4913 744 RLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAF-NREWPAETADLDA-DLESLPEYLALL 821
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2024433729 282 QAEALSDLEMIRKEFKEVEN------------AYEREKQKAQENLEKVNR 319
Cdd:COG4913 822 DRLEEDGLPEYEERFKELLNensiefvadllsKLRRAIREIKERIDPLND 871
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
51-532 |
1.16e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.40 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 51 QAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAiakkDARLTVRTVEEELSDARNKLAElqvfnekL 130
Cdd:COG1196 295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE----ELEEELEEAEEELEEAEAELAE-------A 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 131 QQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESiLQKQNSALQNLSKKMKDMELEHRDCSD 210
Cdd:COG1196 364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER-LERLEEELEELEEALAELEEEEEEEEE 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 211 LLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDL- 289
Cdd:COG1196 443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGl 522
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 290 -----EMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNE--------KIEEKKEIIKDLSERLQENEKIH 356
Cdd:COG1196 523 agavaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratflplDKIRARAALAAALARGAIGAAVD 602
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 357 RELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELK 436
Cdd:COG1196 603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 437 KMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESE 516
Cdd:COG1196 683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762
|
490
....*....|....*.
gi 2024433729 517 NEIQKLTRAYKKDMEE 532
Cdd:COG1196 763 EELERELERLEREIEA 778
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
271-525 |
2.15e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.69 E-value: 2.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 271 LEGALQMEKVSQAEAlsDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKeiikDLSERLQ 350
Cdd:COG4942 13 LAAAAQADAAAEAEA--ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA----ALEAELA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 351 ENEKIHRELQDKLATAKKhqvfvtetyennmiELKLLLDSFAMSGQRTAGTC--KDKDKPSSLSVLETLRYTLTAYQNKL 428
Cdd:COG4942 87 ELEKEIAELRAELEAQKE--------------ELAELLRALYRLGRQPPLALllSPEDFLDAVRRLQYLKYLAPARREQA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 429 EDTSNELKKMNALcentTKELEISRDKMCVLSQDLKEARDKLANANKElnhlhtecadKAALIGTLQMELQNVQQRWEEE 508
Cdd:COG4942 153 EELRADLAELAAL----RAELEAERAELEALLAELEEERAALEALKAE----------RQKLLARLEKELAELAAELAEL 218
|
250
....*....|....*..
gi 2024433729 509 KVRAAESENEIQKLTRA 525
Cdd:COG4942 219 QQEAEELEALIARLEAE 235
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
218-534 |
3.05e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.25 E-value: 3.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 218 KLEYSAEQEERLK---KELEAatdRIKQLEEnfEAERAAH---LKSKFN---LEITQMRIRELEGALQMEKVSQAEALSD 288
Cdd:COG1196 180 KLEATEENLERLEdilGELER---QLEPLER--QAEKAERyreLKEELKeleAELLLLKLRELEAELEELEAELEELEAE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 289 LEMIRKEFKEVENAYEREKQKAQENLEKVNRL-EREYISTNK--QMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLAT 365
Cdd:COG1196 255 LEELEAELAELEAELEELRLELEELELELEEAqAEEYELLAElaRLEQDIARLEERRRELEERLEELEEELAELEEELEE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 366 AKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDkpSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENT 445
Cdd:COG1196 335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA--EAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 446 TKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIgtLQMELQNVQQRWEEEKVRAAESENEIQKLTRA 525
Cdd:COG1196 413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE--EALLELLAELLEEAALLEAALAELLEELAEAA 490
|
....*....
gi 2024433729 526 YKKDMEEKL 534
Cdd:COG1196 491 ARLLLLLEA 499
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
48-533 |
4.03e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 51.56 E-value: 4.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 48 KLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDarltVRTVEEELSDARNKLAELQVF- 126
Cdd:TIGR04523 128 KLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKE----KLNIQKNIDKIKNKLLKLELLl 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 127 ---------NEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKdeyelllkergELESILQKQNSALQNLSKK 197
Cdd:TIGR04523 204 snlkkkiqkNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT-----------QLNQLKDEQNKIKKQLSEK 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 198 MKDMELEHRDCSDlLTRQVHKLEysaEQEERLKKELEAatDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQM 277
Cdd:TIGR04523 273 QKELEQNNKKIKE-LEKQLNQLK---SEISDLNNQKEQ--DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 278 EKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREyistnkqmnekieekkeiIKDLSERLQENEKIHR 357
Cdd:TIGR04523 347 LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ------------------INDLESKIQNQEKLNQ 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 358 ELQDKLATAKKhqvfvtetyENNMIELKL-LLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTlTAYQNKLEDTSNELK 436
Cdd:TIGR04523 409 QKDEQIKKLQQ---------EKELLEKEIeRLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTR-ESLETQLKVLSRSIN 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 437 KMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKElnhlhtecadkaaligtlQMELQNVQQRWEEEKvraAESE 516
Cdd:TIGR04523 479 KIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK------------------ISSLKEKIEKLESEK---KEKE 537
|
490
....*....|....*..
gi 2024433729 517 NEIQKLTRAYKKDMEEK 533
Cdd:TIGR04523 538 SKISDLEDELNKDDFEL 554
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
4-591 |
4.23e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 51.98 E-value: 4.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 4 IMNLSSPVSHVDHEAKRL-CSAKSGSQLLHNSSASEL----DVAEDLKRKL-----CQAKEEKVDIIIKHNQELRDYEIQ 73
Cdd:TIGR01612 2013 ILNDVKLLLHKFDELNKLsCDSQNYDTILELSKQDKIkekiDNYEKEKEKFgidfdVKAMEEKFDNDIKDIEKFENNYKH 2092
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 74 IVKLRSEF-EKGEAIRQSleyalaiaKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQ-----------RLVETEKT- 140
Cdd:TIGR01612 2093 SEKDNHDFsEEKDNIIQS--------KKKLKELTEAFNTEIKIIEDKIIEKNDLIDKLIEmrkecllfsyaTLVETLKSk 2164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 141 ------FHIAQQKWKEQQQRLASEKDDILRTHKDEYEL---LLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDL 211
Cdd:TIGR01612 2165 vinhseFITSAAKFSKDFFEFIEDISDSLNDDIDALQIkynLNQTKKHMISILADATKDHNNLIEKEKEATKIINNLTEL 2244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 212 LTRQVHK-----LEYSAEQEERLKKELEAATDRIKQLEEN---FEAERAAHLKSKFNlEITqmriRELEGALQMEKVSQA 283
Cdd:TIGR01612 2245 FTIDFNNadadiLHNNKIQIIYFNSELHKSIESIKKLYKKinaFKLLNISHINEKYF-DIS----KEFDNIIQLQKHKLT 2319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 284 EALSDLEMIRKEFKEVENAYERE-KQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDK 362
Cdd:TIGR01612 2320 ENLNDLKEIDQYISDKKNIFLHAlNENTNFNFNALKEIYDDIINRENKADEIENINNKENENIMQYIDTITKLTEKIQDI 2399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 363 LatakkhqVFVTeTYENNMIELKLLLdsfamsgqrtagtcKDKDKPSSLSVLETLRYTLTAYQ---NKLEDTSNELKKMN 439
Cdd:TIGR01612 2400 L-------IFVT-TYENDNNIIKQHI--------------QDNDENDVSKIKDNLKKTIQSFQeilNKIDEIKAQFYGGN 2457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 440 ALCENTTKELEISRDKMCVLSQDLK------EARDKLANANKELNHLHTECADK--AALIGTLQMELQNVQQR-WEEEKV 510
Cdd:TIGR01612 2458 NINNIIITISQNANDVKNHFSKDLTieneliQIQKRLEDIKNAAHEIRSEQITKytNAIHNHIEEQFKKIENNsNKDEVY 2537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 511 RAAESENEIQKLtRAYKKDMEEKLTFLHGlYQHLVAGCV--------LIKQPEGILDRFSWsELCAVLQENVDALILDLN 582
Cdd:TIGR01612 2538 KINEIDNIIEKI-INYNKEPEVKLHAIID-NKNEFASIIpdiknliaLIESEYGNNNNISY-KVAIKHEEDANNIILDLN 2614
|
....*....
gi 2024433729 583 RANEKISHL 591
Cdd:TIGR01612 2615 KSQNILNHL 2623
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
33-691 |
4.40e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.51 E-value: 4.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 33 NSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQ--ELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTV- 109
Cdd:pfam02463 183 ENLAELIIDLEELKLQELKLKEQAKKALEYYQLkeKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEk 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 110 EEELSDARNKLAELqvfnEKLQQRLVETEKTFHIAQQKWKEQQQRLAsekddilrthKDEYELLLKERGELESILQKQNS 189
Cdd:pfam02463 263 EEEKLAQVLKENKE----EEKEKKLQEEELKLLAKEEEELKSELLKL----------ERRKVDDEEKLKESEKEKKKAEK 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 190 ALQNLSKKMKDmelehrdcsdlltRQVHKLEYSAEQEERLKKELEAAtdRIKQLEENFEAERAAHLKSKFNLEITQMRIR 269
Cdd:pfam02463 329 ELKKEKEEIEE-------------LEKELKELEIKREAEEEEEEELE--KLQEKLEQLEEELLAKKKLESERLSSAAKLK 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 270 ELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYER----EKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDL 345
Cdd:pfam02463 394 EEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELeileEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 346 SERLQEnEKIHRELQDKLATAKKHQVFVTETYENN--------MIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETL 417
Cdd:pfam02463 474 LKETQL-VKLQEQLELLLSRQKLEERSQKESKARSglkvllalIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVE 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 418 RYTLTAY-------------QNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQ--DLKEARDKLANANKELNHLHT 482
Cdd:pfam02463 553 VSATADEveerqklvralteLPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDkaTLEADEDDKRAKVVEGILKDT 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 483 ECADKAALIGTLQMELQNVQQRweEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFS 562
Cdd:pfam02463 633 ELTKLKESAKAKESGLRKGVSL--EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKE 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 563 WSELCAVLQENVDALILDLNRANEKISHLEYICKsKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLL 642
Cdd:pfam02463 711 ELKKLKLEAEELLADRVQEAQDKINEELKLLKQK-IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 2024433729 643 GEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEH 691
Cdd:pfam02463 790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL 838
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
68-673 |
5.38e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 51.59 E-value: 5.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 68 RDYEIQIVKLRSE---FEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIA 144
Cdd:TIGR00606 366 RDSLIQSLATRLEldgFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELK 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 145 QQKWKEQQQRLASEKDDILRTHKDEYELLLKE----RGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLE 220
Cdd:TIGR00606 446 KEILEKKQEELKFVIKELQQLEGSSDRILELDqelrKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEME 525
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 221 YSAEQEERLKKELEAATDRIKQLEenfeaeraahlkskfnleitqmRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVE 300
Cdd:TIGR00606 526 QLNHHTTTRTQMEMLTKDKMDKDE----------------------QIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKS 583
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 301 NayerEKQKAQENLEKVNrLEREYISTNK-QMNEKIEEKKEIIKDLSERL------QENEKIHRELQDKLATAKKHQVFV 373
Cdd:TIGR00606 584 K----EINQTRDRLAKLN-KELASLEQNKnHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRAML 658
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 374 ---TETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKpsslsVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELE 450
Cdd:TIGR00606 659 agaTAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE-----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAP 733
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 451 ISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGT--------------------LQMELQNVQQRWEEE-- 508
Cdd:TIGR00606 734 GRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTimpeeesakvcltdvtimerFQMELKDVERKIAQQaa 813
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 509 KVRAAESENEIQKLtRAYKKDMEEKLTFL--------------HGLYQHLVA-----GCVLIKQPEGILDRFSWSELCAV 569
Cdd:TIGR00606 814 KLQGSDLDRTVQQV-NQEKQEKQHELDTVvskielnrkliqdqQEQIQHLKSktnelKSEKLQIGTNLQRRQQFEEQLVE 892
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 570 LQENVDALILDLNRANEKISHLEyicksksDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQY---SDLLGEVH 646
Cdd:TIGR00606 893 LSTEVQSLIREIKDAKEQDSPLE-------TFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHgymKDIENKIQ 965
|
650 660 670
....*....|....*....|....*....|.
gi 2024433729 647 ARAQEYKETAEKNKEKICV----LEKRQEEL 673
Cdd:TIGR00606 966 DGKDDYLKQKETELNTVNAqleeCEKHQEKI 996
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
902-1165 |
7.75e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.71 E-value: 7.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 902 EKNSLIQRLAHGLHRINARALEAGScDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKA 981
Cdd:COG1196 264 ELEAELEELRLELEELELELEEAQA-EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 982 QSLKEQLSLFKQSKLIAHKRFESACEELNNALH-WEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSE 1060
Cdd:COG1196 343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAeAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1061 AKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDF 1140
Cdd:COG1196 423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
|
250 260
....*....|....*....|....*
gi 2024433729 1141 TLQLPKLHLETFAVEGLKGGPEVVA 1165
Cdd:COG1196 503 YEGFLEGVKAALLLAGLRGLAGAVA 527
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
51-505 |
1.22e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 51 QAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAiaKKDARLTVRTVEEELSDARNKLAELQVFNEKL 130
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE--KLEKLLQLLPLYQELEALEAELAELPERLEEL 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 131 QQRLvetektfhiaqQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEhrdcsd 210
Cdd:COG4717 152 EERL-----------EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEE------ 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 211 lLTRQVHKLEYSAEQEERLKKELEAATD--RIKQLEENFEAERAAHLKSKFNLEITQmRIRELEGALQMekVSQAEALSD 288
Cdd:COG4717 215 -LEEAQEELEELEEELEQLENELEAAALeeRLKEARLLLLIAAALLALLGLGGSLLS-LILTIAGVLFL--VLGLLALLF 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 289 LEMIRKEFKEVENAYEREKQKAQENLEkvnrlEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKK 368
Cdd:COG4717 291 LLLAREKASLGKEAEELQALPALEELE-----EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 369 HQvfvtetyenNMIELKLLLDSfamsgqrtAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTK- 447
Cdd:COG4717 366 EE---------LEQEIAALLAE--------AGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEe 428
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024433729 448 ----ELEISRDKMCVLSQDLKEARDKLANANKELNHLHT--ECADKAALIGTLQMELQNVQQRW 505
Cdd:COG4717 429 eleeELEELEEELEELEEELEELREELAELEAELEQLEEdgELAELLQELEELKAELRELAEEW 492
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
157-673 |
1.45e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 157 SEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMElEHRDCSDLLTRQVHKLEYSAEQEERLKKELEaa 236
Cdd:PRK03918 189 ENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE-ELKEEIEELEKELESLEGSKRKLEEKIRELE-- 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 237 tDRIKQLEENFEaeraahlkskfNLEITQMRIRELEGalqmekvsQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEK 316
Cdd:PRK03918 266 -ERIEELKKEIE-----------ELEEKVKELKELKE--------KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEING 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 317 VNRLereyISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFA---- 392
Cdd:PRK03918 326 IEER----IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEkake 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 393 --------MSGQRTAGTCKDKDKPSSLSVLETLRYT----------------LTAYQNKLEDTSNELKKMNALCE---NT 445
Cdd:PRK03918 402 eieeeiskITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelteehrkelLEEYTAELKRIEKELKEIEEKERklrKE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 446 TKELEISRDKMCVLSQdLKEARDKLANANKELNHLHTECADKAA--------LIGTLQMELQNVQQRWEEEKvraaESEN 517
Cdd:PRK03918 482 LRELEKVLKKESELIK-LKELAEQLKELEEKLKKYNLEELEKKAeeyeklkeKLIKLKGEIKSLKKELEKLE----ELKK 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 518 EIQKLTRAyKKDMEEKLTFLHGLYQHLVAGCVL-----IKQPEGILDRF-----SWSELcAVLQENVDALILDLNRANEK 587
Cdd:PRK03918 557 KLAELEKK-LDELEEELAELLKELEELGFESVEeleerLKELEPFYNEYlelkdAEKEL-EREEKELKKLEEELDKAFEE 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 588 ISHLEYICKSKSDTMKELQRS-QEDDMSKMAEQMKAQESCWQKQKKYLEqqysdllgEVHARAQEYKETAEKNKEKICVL 666
Cdd:PRK03918 635 LAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRAELE--------ELEKRREEIKKTLEKLKEELEER 706
|
....*..
gi 2024433729 667 EKRQEEL 673
Cdd:PRK03918 707 EKAKKEL 713
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
40-251 |
2.07e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 49.57 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 40 DVAEDLKRKLCQAKEEKvDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYA-----LAIAKKDARLTVRTVEEELS 114
Cdd:COG3096 893 DRLEELREELDAAQEAQ-AFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAkeqqrRLKQQIFALSEVVQRRPHFS 971
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 115 --DARNKLAELQVFNEKLQQRLVETEktfhiaqqkwkeqQQRlaSEKDDILRTHKDEYELLLKERGELESILQKQNSALQ 192
Cdd:COG3096 972 yeDAVGLLGENSDLNEKLRARLEQAE-------------EAR--REAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQ 1036
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024433729 193 NLSKKMKDMEL------------EHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAER 251
Cdd:COG3096 1037 ELEQELEELGVqadaeaeerariRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQER 1107
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
105-529 |
2.43e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.95 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 105 TVRTVEEELSDARNKLA----ELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQrlasekddiLRTHKDEYELLLKERGEL 180
Cdd:pfam05483 357 TTCSLEELLRTEQQRLEknedQLKIITMELQKKSSELEEMTKFKNNKEVELEE---------LKKILAEDEKLLDEKKQF 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 181 ESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEEN-----FEAERAAHL 255
Cdd:pfam05483 428 EKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHcdkllLENKELTQE 507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 256 KSKFNLE-------ITQMRIRELEGALQMEKVSQAEA--LSDLEMIRKEFKEVENAYEREKQKAQENLEKVnrlEREYIS 326
Cdd:pfam05483 508 ASDMTLElkkhqedIINCKKQEERMLKQIENLEEKEMnlRDELESVREEFIQKGDEVKCKLDKSEENARSI---EYEVLK 584
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 327 TNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQ--DKLATAKKHQVFVtetYENNMIELKLLLDSFAMSGQRTAGTCKD 404
Cdd:pfam05483 585 KEKQMKILENKCNNLKKQIENKNKNIEELHQENKalKKKGSAENKQLNA---YEIKVNKLELELASAKQKFEEIIDNYQK 661
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 405 KDKPSSLSVlETLRYTLTAYQNKLEDTSNELKKMNALCENTTKEleisrdkMCVLSQDLKEARDKLANA-NKELNHLHTE 483
Cdd:pfam05483 662 EIEDKKISE-EKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAE-------MVALMEKHKHQYDKIIEErDSELGLYKNK 733
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 2024433729 484 CADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKD 529
Cdd:pfam05483 734 EQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKEN 779
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
54-588 |
2.65e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 2.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 54 EEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQS-LEYALAIAKKD------ARLTVRTVEEELSDARNKLAELQVF 126
Cdd:COG4913 224 FEAADALVEHFDDLERAHEALEDAREQIELLEPIRELaERYAAARERLAeleylrAALRLWFAQRRLELLEAELEELRAE 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 127 NEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNL-------SKKMK 199
Cdd:COG4913 304 LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALglplpasAEEFA 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 200 DMELEHRDCSDLLTRQVHKLE---YSAEQEER-LKKELEAATDRIKQLEENfeaeraahlKSKFNLEITQMRiRELEGAL 275
Cdd:COG4913 384 ALRAEAAALLEALEEELEALEealAEAEAALRdLRRELRELEAEIASLERR---------KSNIPARLLALR-DALAEAL 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 276 qmeKVSQAEA--LSDLEMIRKEFKEVENAYER-----------EKQKAQENLEKVNRLE-REYISTNKQMNEKIEEKKEI 341
Cdd:COG4913 454 ---GLDEAELpfVGELIEVRPEEERWRGAIERvlggfaltllvPPEHYAAALRWVNRLHlRGRLVYERVRTGLPDPERPR 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 342 IKD--LSERLQENEKIHRE-LQDKLATA------------KKHQVFVTETyenNMIelkllldsfamSGQRTAGTCKDKD 406
Cdd:COG4913 531 LDPdsLAGKLDFKPHPFRAwLEAELGRRfdyvcvdspeelRRHPRAITRA---GQV-----------KGNGTRHEKDDRR 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 407 KPSSLSVL--------ETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISR--DKMCVLSQDLKEARDKLANANKE 476
Cdd:COG4913 597 RIRSRYVLgfdnraklAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAE 676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 477 LNHLHTECADKAAL---IGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAyKKDMEEKLTFLHGLYQHLVAGCvLIKQ 553
Cdd:COG4913 677 LERLDASSDDLAALeeqLEELEAELEELEEELDELKGEIGRLEKELEQAEEE-LDELQDRLEAAEDLARLELRAL-LEER 754
|
570 580 590
....*....|....*....|....*....|....*
gi 2024433729 554 PEGILDRFSWSELCAVLQENVDALILDLNRANEKI 588
Cdd:COG4913 755 FAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
43-514 |
2.78e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 48.96 E-value: 2.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 43 EDLKRKLCQAKEEKVDIIIKHNQE-----LRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDAR 117
Cdd:pfam15921 244 EDQLEALKSESQNKIELLLQQHQDrieqlISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 118 NKLA----ELQVFNEKLQQRLVETEKTFHIAQQKWKE---QQQRLASEK---DDILRT-----HKDEYELLL-KERGE-- 179
Cdd:pfam15921 324 STVSqlrsELREAKRMYEDKIEELEKQLVLANSELTEartERDQFSQESgnlDDQLQKlladlHKREKELSLeKEQNKrl 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 180 -------------LESILQKQNSALQNLSKKMKDMELEhrdCSDLLTRQVHKLEYSAEQEER---LKKELEAATDRIKQL 243
Cdd:pfam15921 404 wdrdtgnsitidhLRRELDDRNMEVQRLEALLKAMKSE---CQGQMERQMAAIQGKNESLEKvssLTAQLESTKEMLRKV 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 244 EENFEAEraahlksKFNLEITQMRIRELEGALQmEKVSQAEA---------------LSDLEMIRKEFKEVENAYER--- 305
Cdd:pfam15921 481 VEELTAK-------KMTLESSERTVSDLTASLQ-EKERAIEAtnaeitklrsrvdlkLQELQHLKNEGDHLRNVQTEcea 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 306 ------EKQKA----QENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQE--------NEKIhRELQDKLATAK 367
Cdd:pfam15921 553 lklqmaEKDKVieilRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkDAKI-RELEARVSDLE 631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 368 KHQVFVTETYENNMIELK-------LLLDSFAMSGQRTAGTCKD--------KDKPSSL-SVLETLRYTLTAYQNKLEDT 431
Cdd:pfam15921 632 LEKVKLVNAGSERLRAVKdikqerdQLLNEVKTSRNELNSLSEDyevlkrnfRNKSEEMeTTTNKLKMQLKSAQSELEQT 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 432 SNELKKMNA-------LCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTL---------Q 495
Cdd:pfam15921 712 RNTLKSMEGsdghamkVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVateknkmagE 791
|
570
....*....|....*....
gi 2024433729 496 MELQNVQQRWEEEKVRAAE 514
Cdd:pfam15921 792 LEVLRSQERRLKEKVANME 810
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
936-1127 |
2.90e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.78 E-value: 2.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 936 IASLQKQIAEFTQRLHTVEVERCSLRRELAEFKlnfSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHW 1015
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELE---AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1016 EHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHD 1095
Cdd:COG1196 311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390
|
170 180 190
....*....|....*....|....*....|..
gi 2024433729 1096 AESALCMAAKDRELIINQMKSVEATLHTVRDQ 1127
Cdd:COG1196 391 ALRAAAELAAQLEELEEAEEALLERLERLEEE 422
|
|
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
98-315 |
3.56e-05 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 46.59 E-value: 3.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 98 AKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTfhIAQQKWKEQQQRLASEKddilrthkdEYELLLKER 177
Cdd:pfam05010 9 ALEKARNEIEEKELEINELKAKYEELRRENLEMRKIVAEFEKT--IAQMIEEKQKQKELEHA---------EIQKVLEEK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 178 GELESILQKQNSALQNLSKKMKdmelehrdcsdlltRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERaAHLKS 257
Cdd:pfam05010 78 DQALADLNSVEKSFSDLFKRYE--------------KQKEVISGYKKNEESLKKCAQDYLARIKKEEQRYQALK-AHAEE 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024433729 258 KF---NLEITQMRIRelegalqmekvSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLE 315
Cdd:pfam05010 143 KLdqaNEEIAQVRSK-----------AKAETAALQASLRKEQMKVQSLERQLEQKTKENEE 192
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
420-658 |
4.38e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 4.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 420 TLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQ 499
Cdd:COG4942 14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 500 NVQQRWEEEKVRAAESeneiqkLTRAYKKDMEEKLTFLhglyqhlvagcVLIKQPEGILDRFSW-SELCAVLQENVDALI 578
Cdd:COG4942 94 ELRAELEAQKEELAEL------LRALYRLGRQPPLALL-----------LSPEDFLDAVRRLQYlKYLAPARREQAEELR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 579 LDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKY------LEQQYSDLLGEVHARAQEY 652
Cdd:COG4942 157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELaaelaeLQQEAEELEALIARLEAEA 236
|
....*.
gi 2024433729 653 KETAEK 658
Cdd:COG4942 237 AAAAER 242
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
303-1127 |
6.29e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 6.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 303 YEREKQKAQENLEKVnrleREYISTNKQMnekieekkeiikdLSERLQENEKihreLQDKLATAKKHQVFVTETYEnnmI 382
Cdd:TIGR02169 168 FDRKKEKALEELEEV----EENIERLDLI-------------IDEKRQQLER----LRREREKAERYQALLKEKRE---Y 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 383 ELKLLLDSF-AMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNEL-KKMNALCENTTKELeisRDKMCVLS 460
Cdd:TIGR02169 224 EGYELLKEKeALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGEEEQLRV---KEKIGELE 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 461 QDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKK---DMEEKLTFL 537
Cdd:TIGR02169 301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDlraELEEVDKEF 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 538 HGLYQHLVAgcvLIKQPEGILDRFSwselcaVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMA 617
Cdd:TIGR02169 381 AETRDELKD---YREKLEKLKREIN------ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 618 EQMKAQESCWQKQKKYlEQQYSDLlgevharaqeyketaeknKEKICVLEKRQEELALENLYVKNTLTQIQKEHSsllaa 697
Cdd:TIGR02169 452 KQEWKLEQLAADLSKY-EQELYDL------------------KEEYDRVEKELSKLQRELAEAEAQARASEERVR----- 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 698 callagalyplYGRScamsiQRDLLQDQVN-IYELVNQEIR------TLVHILSG-----VEEEKEDDAK--IKKHKFRg 763
Cdd:TIGR02169 508 -----------GGRA-----VEEVLKASIQgVHGTVAQLGSvgeryaTAIEVAAGnrlnnVVVEDDAVAKeaIELLKRR- 570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 764 lihvfRRGVIAVLAANRLKVLAQSSSSLfsLINGFkegIGILVcvgdskgkhNMSRYNKEgircVEALNWFTSPDllTAV 843
Cdd:TIGR02169 571 -----KAGRATFLPLNKMRDERRDLSIL--SEDGV---IGFAV---------DLVEFDPK----YEPAFKYVFGD--TLV 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 844 ISSVTELQDVISK----------TDPKSCLSGRLLVSAARNSFSKlMDKLNVIMESVPLDSSRSvtyvEKNSLIQRLAHG 913
Cdd:TIGR02169 626 VEDIEAARRLMGKyrmvtlegelFEKSGAMTGGSRAPRGGILFSR-SEPAELQRLRERLEGLKR----ELSSLQSELRRI 700
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 914 LHRINA--RALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFK-----LNFSKMKQEADKAQsLKE 986
Cdd:TIGR02169 701 ENRLDElsQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKselkeLEARIEELEEDLHK-LEE 779
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 987 QLSLFKQSKLIA---------------HKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKnqvL 1051
Cdd:TIGR02169 780 ALNDLEARLSHSripeiqaelskleeeVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE---I 856
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024433729 1052 SETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQ 1127
Cdd:TIGR02169 857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
17-519 |
6.55e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 6.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 17 EAKRLCSAKSGSQLLHNSSASELDVAEDLKRKlcQAKEEKVDIIIKHNQELRDYEiQIVKLRSEFEKGEAIRQSLEYAla 96
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKA--AAAKKKADEAKKKAEEKKKAD-EAKKKAEEAKKADEAKKKAEEA-- 1456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 97 iaKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFH----IAQQKWKEQQQRLASEKDDILRTHKDEYEl 172
Cdd:PTZ00121 1457 --KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADeakkAAEAKKKADEAKKAEEAKKADEAKKAEEA- 1533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 173 llKERGELESILQKQNSalQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERA 252
Cdd:PTZ00121 1534 --KKADEAKKAEEKKKA--DELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 253 AHLKSKFNLEITQMRIR---ELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNK 329
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEELKkaeEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK 1689
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 330 ----------------QMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKK--HQVFVTETYENNMIELKLLLDSF 391
Cdd:PTZ00121 1690 aaealkkeaeeakkaeELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKkaEEAKKDEEEKKKIAHLKKEEEKK 1769
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 392 AMSGQRTAGTC-----KDKDKPSSLSVLETLRYTLTAYQNKLEDTsnelkKMNALCENTTKELEISRDKMCVLSQDL--- 463
Cdd:PTZ00121 1770 AEEIRKEKEAVieeelDEEDEKRRMEVDKKIKDIFDNFANIIEGG-----KEGNLVINDSKEMEDSAIKEVADSKNMqle 1844
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024433729 464 --KEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEI 519
Cdd:PTZ00121 1845 eaDAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREI 1902
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
927-1137 |
9.92e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 9.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 927 CDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLR--RELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAhkRFES 1004
Cdd:COG4913 218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQIEllEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLE--LLEA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1005 ACEELNNALHwehQAQVLLNEQAQQLQELNNKLELHsseeadKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQ 1084
Cdd:COG4913 296 ELEELRAELA---RLEAELERLEARLDALREELDEL------EAQIRGNGGDRLEQLEREIERLERELEERERRRARLEA 366
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2024433729 1085 DKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATR 1137
Cdd:COG4913 367 LLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR 419
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
934-1091 |
1.01e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 934 KSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQS-------KLIAHKRFESAC 1006
Cdd:COG4942 69 RRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEdfldavrRLQYLKYLAPAR 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1007 EELNNALHWE----HQAQVLLNEQAQQLQELNNKLELH----SSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRL 1078
Cdd:COG4942 149 REQAEELRADlaelAALRAELEAERAELEALLAELEEEraalEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
170
....*....|...
gi 2024433729 1079 LTQLEQDKRRLKE 1091
Cdd:COG4942 229 IARLEAEAAAAAE 241
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
920-1093 |
1.05e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 920 RALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQE-ADKAQSLKEQL-SLFKQSKLI 997
Cdd:COG4942 41 KELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAElEAQKEELAELLrALYRLGRQP 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 998 AHKRFESAcEELNNALHWEHQAQVLLNEQAQQLQELNNKLElhssEEADKNQVLSETVKRLSEAKMELRRKDQSLRQL-- 1075
Cdd:COG4942 121 PLALLLSP-EDFLDAVRRLQYLKYLAPARREQAEELRADLA----ELAALRAELEAERAELEALLAELEEERAALEALka 195
|
170 180
....*....|....*....|
gi 2024433729 1076 --NRLLTQLEQDKRRLKESI 1093
Cdd:COG4942 196 erQKLLARLEKELAELAAEL 215
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
35-380 |
1.07e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 47.27 E-value: 1.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 35 SASELDVAEDLKRKLCQAKEEKVDII-IKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEEL 113
Cdd:pfam02463 702 KKKEQREKEELKKLKLEAEELLADRVqEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 114 SDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQN 193
Cdd:pfam02463 782 KTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEE 861
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 194 LSKKMKdmELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEG 273
Cdd:pfam02463 862 EITKEE--LLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 274 ALQMEKVSQAEALSDLEMIRKEFKEVENAYErekqkaqeNLEKVN-RLEREYISTNKQMNEKIEEKkeiikdlsERLQEN 352
Cdd:pfam02463 940 LLLEEADEKEKEENNKEEEEERNKRLLLAKE--------ELGKVNlMAIEEFEEKEERYNKDELEK--------ERLEEE 1003
|
330 340
....*....|....*....|....*...
gi 2024433729 353 EKIHRELQDKLATAKKHQVFVTETYENN 380
Cdd:pfam02463 1004 KKKLIRAIIEETCQRLKEFLELFVSINK 1031
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
40-244 |
1.50e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.87 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 40 DVAEDLKRKLCQAKEEKVDIIiKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAI-----AKKDARLTVRTVEEELS 114
Cdd:PRK04863 894 DRVEEIREQLDEAEEAKRFVQ-QHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTqrdakQQAFALTEVVQRRAHFS 972
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 115 --DARNKLAELQVFNEKLQQRLVEtektfhiaqqkwKEQQQRLASEKddiLRTHKDEYELLLKERGELESILQKQNSALQ 192
Cdd:PRK04863 973 yeDAAEMLAKNSDLNEKLRQRLEQ------------AEQERTRAREQ---LRQAQAQLAQYNQVLASLKSSYDAKRQMLQ 1037
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2024433729 193 NLSKKMKDMELehRDCSDLLTRqvhkleySAEQEERLKKELEAATDRIKQLE 244
Cdd:PRK04863 1038 ELKQELQDLGV--PADSGAEER-------ARARRDELHARLSANRSRRNQLE 1080
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
975-1121 |
1.76e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.47 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 975 KQEADKA---QSLKEQLSLFKQSKLIAHKRF------------ESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLEL 1039
Cdd:COG1196 206 ERQAEKAeryRELKEELKELEAELLLLKLREleaeleeleaelEELEAELEELEAELAELEAELEELRLELEELELELEE 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1040 HSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEA 1119
Cdd:COG1196 286 AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365
|
..
gi 2024433729 1120 TL 1121
Cdd:COG1196 366 AL 367
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
43-244 |
1.76e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.16 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 43 EDLKRKLCQAKEEKVDIIIKHN------------QELRDYEIQIVKLRSEFEKGEAIRQSLEYALAiaKKDARLTVRTVE 110
Cdd:COG3206 185 PELRKELEEAEAALEEFRQKNGlvdlseeaklllQQLSELESQLAEARAELAEAEARLAALRAQLG--SGPDALPELLQS 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 111 EELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSA 190
Cdd:COG3206 263 PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEAR 342
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2024433729 191 LQNLSKKmkdmELEHRDcsdlLTRQVhkleysaeqeERLKKELEAATDRIKQLE 244
Cdd:COG3206 343 LAELPEL----EAELRR----LEREV----------EVARELYESLLQRLEEAR 378
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
127-348 |
1.84e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 46.27 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 127 NEKLQQRL--VETEKTFHIAQQKWK---EQQQRLASEKDDILRTHKDEYELLLKERG-------------ELESILQKQN 188
Cdd:pfam17380 268 NEFLNQLLhiVQHQKAVSERQQQEKfekMEQERLRQEKEEKAREVERRRKLEEAEKArqaemdrqaaiyaEQERMAMERE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 189 SALQNLSKKMKDMELEHRDCSDLLT-----RQVHKLEYSAEQE-ERLKKELEAA--------------------TDRIKQ 242
Cdd:pfam17380 348 RELERIRQEERKRELERIRQEEIAMeisrmRELERLQMERQQKnERVRQELEAArkvkileeerqrkiqqqkveMEQIRA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 243 LEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALsdlemiRKEFKEVENAYEREKQKAQENLEKVnrLER 322
Cdd:pfam17380 428 EQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEE------RKRKKLELEKEKRDRKRAEEQRRKI--LEK 499
|
250 260
....*....|....*....|....*.
gi 2024433729 323 EYISTNKQMNEKIEEKKEIIKDLSER 348
Cdd:pfam17380 500 ELEERKQAMIEEERKRKLLEKEMEER 525
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
83-519 |
2.15e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 45.89 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 83 KGEAIRQSLEY--ALAIAKKDARLTVRTVEEElsdaRNKLAELQVFNEKLQQRLVETEKTFH----IAQQKWK--EQQQR 154
Cdd:pfam05557 15 QNEKKQMELEHkrARIELEKKASALKRQLDRE----SDRNQELQKRIRLLEKREAEAEEALReqaeLNRLKKKylEALNK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 155 LASEKDDILRTHKDEYELLLKERGELESILQKQNSALQnlskkmkdmelehrdcsdlltRQVHKLEYSAEQEERLKKELE 234
Cdd:pfam05557 91 KLNEKESQLADAREVISCLKNELSELRRQIQRAELELQ---------------------STNSELEELQERLDLLKAKAS 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 235 AATDRIKQLEenfeaeraahlKSKFNLEITQMRIRELEGALQME-------KVSQAEALSDLEMIR-KEFKEVENAYERE 306
Cdd:pfam05557 150 EAEQLRQNLE-----------KQQSSLAEAEQRIKELEFEIQSQeqdseivKNSKSELARIPELEKeLERLREHNKHLNE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 307 KQKAQENL-EKVNRLEREYISTNKQMnekieekkeiiKDLSERLQENEKIHRELQD--KLATAKKHQVFVTETYENNMIE 383
Cdd:pfam05557 219 NIENKLLLkEEVEDLKRKLEREEKYR-----------EEAATLELEKEKLEQELQSwvKLAQDTGLNLRSPEDLSRRIEQ 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 384 lkLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETlryTLTAYQNKLEDTSNELKKMNALCENTTKELEIsrdkmcvLSQDL 463
Cdd:pfam05557 288 --LQQREIVLKEENSSLTSSARQLEKARRELEQ---ELAQYLKKIEDLNKKLKRHKALVRRLQRRVLL-------LTKER 355
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024433729 464 KEARDKLANANKELNHLHTECADKAALIGTLQMeLQNVQQRWEEEKVRAAESENEI 519
Cdd:pfam05557 356 DGYRAILESYDKELTMSNYSPQLLERIEEAEDM-TQKMQAHNEEMEAQLSVAEEEL 410
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
93-361 |
2.33e-04 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 46.09 E-value: 2.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 93 YALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIaQQKWKEQQQRLASEKDDILRTHKDEYEL 172
Cdd:pfam15818 74 CALEEEKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKVSEMEQKLQL-HLLAKEDHHKQLNEIEKYYATITGQFGL 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 173 LLKERGELESILQ--------------KQNSALQNLSKKMKDMelehrdCSDLLTRQV---HKLEysaeqEERLkkELEA 235
Cdd:pfam15818 153 VKENHGKLEQNVQeaiqlnkrlsalnkKQESEICSLKKELKKV------TSDLIKSKVtcqYKMG-----EENI--NLTI 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 236 ATDRIKQLEENFEAERAahLKSKFNLEITQMR---------IRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYERE 306
Cdd:pfam15818 220 KEQKFQELQERLNMELE--LNKKINEEITHIQeekqdiiisFQHMQQLLQQQTQANTEMEAELKALKENNQTLERDNELQ 297
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2024433729 307 KQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQD 361
Cdd:pfam15818 298 REKVKENEEKFLNLQNEHEKALGTWKKHVEELNGEINEIKNELSSLKETHIKLQE 352
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
148-265 |
2.62e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 45.01 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 148 WKEQQQR-LASEKDDILRTHKDEYELLLKERGELESI---LQKQNSALQNLSKKMKDMELEHRDC-SDLLTRQVHKLEYS 222
Cdd:smart00787 137 WRMKLLEgLKEGLDENLEGLKEDYKLLMKELELLNSIkpkLRDRKDALEEELRQLKQLEDELEDCdPTELDRAKEKLKKL 216
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2024433729 223 AEQEERLKKELEAATDRIKQLEENFEAERAahLKSKFNLEITQ 265
Cdd:smart00787 217 LQEIMIKVKKLEELEEELQELESKIEDLTN--KKSELNTEIAE 257
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
123-330 |
2.63e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 123 LQVFNEKLQQRLVE----TEKTFHIAQQKWKEQQQRLASEKDdilrtHKDEYELLLKERGELESILQKQNSALQNLSKKM 198
Cdd:COG4717 44 RAMLLERLEKEADElfkpQGRKPELNLKELKELEEELKEAEE-----KEEEYAELQEELEELEEELEELEAELEELREEL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 199 KDMElehrdcsdlltrQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEA-ERAAHLKSKFNLEITQMRiRELEGALQM 277
Cdd:COG4717 119 EKLE------------KLLQLLPLYQELEALEAELAELPERLEELEERLEElRELEEELEELEAELAELQ-EELEELLEQ 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024433729 278 EKVSQAEALSDL----EMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQ 330
Cdd:COG4717 186 LSLATEEELQDLaeelEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
91-292 |
2.76e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.78 E-value: 2.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 91 LEYALAIAKKDARLTVRTVEEELSDARNKL----AELQVFNEK-------------------LQQRLVETEKTFHIAQQK 147
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEQLPELRKELeeaeAALEEFRQKnglvdlseeaklllqqlseLESQLAEARAELAEAEAR 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 148 WKEQQQRLASEK--------DDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDME--LEHRDCSDLLTRQVh 217
Cdd:COG3206 242 LAALRAQLGSGPdalpellqSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRaqLQQEAQRILASLEA- 320
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024433729 218 KLEYSAEQEERLKKELEAATDRIKQLEENfEAERAAhLKSkfNLEITQMRIRELEGALQMEKVSQAEALSDLEMI 292
Cdd:COG3206 321 ELEALQAREASLQAQLAQLEARLAELPEL-EAELRR-LER--EVEVARELYESLLQRLEEARLAEALTVGNVRVI 391
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
936-1121 |
4.83e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 936 IASLQKQIAEFTQRLHTVEVERCSLRRELAEFKlNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHW 1015
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELEKVLKKES-ELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKG 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1016 EhqaQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKM----ELRRKDQSLRQLNRLLTQL---EQDKRR 1088
Cdd:PRK03918 540 E---IKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFesveELEERLKELEPFYNEYLELkdaEKELER 616
|
170 180 190
....*....|....*....|....*....|...
gi 2024433729 1089 LKESIHDAESALCMAAKDRELIINQMKSVEATL 1121
Cdd:PRK03918 617 EEKELKKLEEELDKAFEELAETEKRLEELRKEL 649
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
42-204 |
7.15e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.66 E-value: 7.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 42 AEDLKRKLCQAKEEKVDIII------KHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYAL----AIAKKDARLTVRTVEE 111
Cdd:TIGR01612 1564 AEKSEQKIKEIKKEKFRIEDdaakndKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLketeSIEKKISSFSIDSQDT 1643
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 112 ELSDARNKLAELQVFNEKL--QQRLVETEKTfhiaqqKWKEQQQRLASEKDDIlRTHKDEYELLLKE---------RGEL 180
Cdd:TIGR01612 1644 ELKENGDNLNSLQEFLESLkdQKKNIEDKKK------ELDELDSEIEKIEIDV-DQHKKNYEIGIIEkikeiaianKEEI 1716
|
170 180
....*....|....*....|....
gi 2024433729 181 ESILQKQNSALQNLSKKMKDMELE 204
Cdd:TIGR01612 1717 ESIKELIEPTIENLISSFNTNDLE 1740
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
66-681 |
7.74e-04 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 44.30 E-value: 7.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 66 ELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIakKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQ 145
Cdd:COG5022 811 EYRSYLACIIKLQKTIKREKKLRETEEVEFSL--KAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELK 888
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 146 QKWKEQQQR-LASEKDDilrthkdeyELLLKERGELESILQKQNSALQNLSKKMKDMeLEHRDCSDLLTRQVHKLEYSA- 223
Cdd:COG5022 889 IDVKSISSLkLVNLELE---------SEIIELKKSLSSDLIENLEFKTELIARLKKL-LNNIDLEEGPSIEYVKLPELNk 958
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 224 --EQEERLKKELEAATDRIKQLEENFEAERAAHLKSK-FNLEITQmrIRELEGALQmEKVSQAEALsDLEMIRKE----F 296
Cdd:COG5022 959 lhEVESKLKETSEEYEDLLKKSTILVREGNKANSELKnFKKELAE--LSKQYGALQ-ESTKQLKEL-PVEVAELQsaskI 1034
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 297 KEVENAYEREKQKAQE----NLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQ----DKLATAKK 368
Cdd:COG5022 1035 ISSESTELSILKPLQKlkglLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEvtnrNLVKPANV 1114
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 369 HQVFVTETYENNMIE-----LKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTL--------TAYQNKLEDTSNEL 435
Cdd:COG5022 1115 LQFIVAQMIKLNLLQeiskfLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPpfaalsekRLYQSALYDEKSKL 1194
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 436 KkmnaLCENTTKELEIsrDKMCVLSQDLKEARDKLANANKELNHLHTEcadKAALIGTLQMELQNVQQRWEE-EKVRaaE 514
Cdd:COG5022 1195 S----SSEVNDLKNEL--IALFSKIFSGWPRGDKLKKLISEGWVPTEY---STSLKGFNNLNKKFDTPASMSnEKLL--S 1263
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 515 SENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVlikqPEGILDRfSWSELCAVLQENVDALILD-------LNRANEK 587
Cdd:COG5022 1264 LLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLF----NALRTKA-SSLRWKSATEVNYNSEELDdwcrefeISDVDEE 1338
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 588 ISHLEyicksksDTMKELQRsQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARaqeyKETAEKNKEKICVLE 667
Cdd:COG5022 1339 LEELI-------QAVKVLQL-LKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKENNLP----KEILKKIEALLIKQE 1406
|
650
....*....|....
gi 2024433729 668 KRQEELALENLYVK 681
Cdd:COG5022 1407 LQLSLEGKDETEVH 1420
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
964-1121 |
8.49e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 8.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 964 LAEFKLNFSKMKQEADKAQSLKEQLS-LFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELH-- 1040
Cdd:TIGR02168 195 LNELERQLKSLERQAEKAERYKELKAeLRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELrl 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1041 -----SSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMK 1115
Cdd:TIGR02168 275 evselEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354
|
....*.
gi 2024433729 1116 SVEATL 1121
Cdd:TIGR02168 355 SLEAEL 360
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
100-318 |
8.62e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.67 E-value: 8.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 100 KDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLAsekddilrthkdeyelllkergE 179
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIE----------------------E 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 180 LESILQKQNSALQNLSKKMKDME--LEHRDCSDLLTRqVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAahlks 257
Cdd:COG3883 84 RREELGERARALYRSGGSVSYLDvlLGSESFSDFLDR-LSALSKIADADADLLEELKADKAELEAKKAELEAKLA----- 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024433729 258 kfNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVN 318
Cdd:COG3883 158 --ELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
66-257 |
1.10e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.60 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 66 ELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDarltVRTVEEELSDARNKLAELQVFNEKLQQRLvetektfhiaq 145
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELEDELAALEAR----LEAAKTELEDLEKEIKRLELEIEEVEARI----------- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 146 QKWKEQQQRLASEKddilrthkdEYELLLKErgelesiLQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQ 225
Cdd:COG1579 76 KKYEEQLGNVRNNK---------EYEALQKE-------IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE 139
|
170 180 190
....*....|....*....|....*....|..
gi 2024433729 226 EERLKKELEAATDRIKQLEENFEAERAAHLKS 257
Cdd:COG1579 140 LEEKKAELDEELAELEAELEELEAEREELAAK 171
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
101-298 |
1.21e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 101 DARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFH----IAQQKWKEQQQRLASEKddiLRTHKDEYELLLKE 176
Cdd:COG4913 607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalqrLAEYSWDEIDVASAERE---IAELEAELERLDAS 683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 177 RGELESiLQKQnsaLQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQ-LEENFEAERAAHL 255
Cdd:COG4913 684 SDDLAA-LEEQ---LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAAL 759
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2024433729 256 KSKFNLEITqmriRELEGALQMEKVSQAEALSDLEMIRKEFKE 298
Cdd:COG4913 760 GDAVERELR----ENLEERIDALRARLNRAEEELERAMRAFNR 798
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
36-533 |
1.25e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.59 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 36 ASELDVAEDLKRKLCQAKE-EKVdiiiKHNQELRDYE---IQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEE 111
Cdd:PTZ00121 1226 AEAVKKAEEAKKDAEEAKKaEEE----RNNEEIRKFEearMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 112 ELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRL------ASEKDDILRTHKDEYELLLKERGELEsilQ 185
Cdd:PTZ00121 1302 KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAeaakaeAEAAADEAEAAEEKAEAAEKKKEEAK---K 1378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 186 KQNSALQNLSKKMKDMELEHRDCSD-LLTRQVHKLEYSAEQEERLKK---ELEAATDRIKQLEENFEAE----RAAHLKS 257
Cdd:PTZ00121 1379 KADAAKKKAEEKKKADEAKKKAEEDkKKADELKKAAAAKKKADEAKKkaeEKKKADEAKKKAEEAKKADeakkKAEEAKK 1458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 258 KFNLEITQMRIRELEGALQM--EKVSQAEALSDLEMIRKEFKEVENAYE-----------REKQKAQENLEKVNRLEREY 324
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEAKKKaeEAKKADEAKKKAEEAKKKADEAKKAAEakkkadeakkaEEAKKADEAKKAEEAKKADE 1538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 325 ISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKD 404
Cdd:PTZ00121 1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 405 KDKPSSLSVLETLRYTLTAYQNKLEDtsnELKKmnalCENTTKELEISRDKMCVLSQDLKEARDKLANANKElnhlhTEC 484
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAE---EKKK----AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA-----EED 1686
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024433729 485 ADKAALIGTLQME----LQNVQQRWEEEK-----VRAAESENEIqKLTRAYKKDMEEK 533
Cdd:PTZ00121 1687 EKKAAEALKKEAEeakkAEELKKKEAEEKkkaeeLKKAEEENKI-KAEEAKKEAEEDK 1743
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
44-692 |
1.29e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.50 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 44 DLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARltVRTVEEELSDARNKLAEL 123
Cdd:TIGR00606 443 ELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKE--VKSLQNEKADLDRKLRKL 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 124 QVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLasekdDILRTHKDEYELLLKE---RGELESILQKQNSALQNLSKKMKD 200
Cdd:TIGR00606 521 DQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIR-----KIKSRHSDELTSLLGYfpnKKQLEDWLHSKSKEINQTRDRLAK 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 201 MELEHRDCSDLLTRQVHKLEYSAEQEERLKKEL------EAATDRIKQLEENFEAERA--AHLKSKFNLE---ITQMRIR 269
Cdd:TIGR00606 596 LNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKqrAMLAGATAVYsqfITQLTDE 675
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 270 ELEGALQMEKVSQAEA-----LSDLE-MIR---KEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKE 340
Cdd:TIGR00606 676 NQSCCPVCQRVFQTEAelqefISDLQsKLRlapDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQK 755
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 341 IIKDLSE---RLQENEKIHRELQDKLATAKKHQVFVT-------ETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSS 410
Cdd:TIGR00606 756 VNRDIQRlknDIEEQETLLGTIMPEEESAKVCLTDVTimerfqmELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQ 835
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 411 lsvlETLRyTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAAL 490
Cdd:TIGR00606 836 ----HELD-TVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 491 IGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCV-LIKQPEGILDRFSWS-ELCA 568
Cdd:TIGR00606 911 DSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDdYLKQKETELNTVNAQlEECE 990
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 569 VLQENVDALI------LDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAE-QMKAQESCWQKQKKYLE------ 635
Cdd:TIGR00606 991 KHQEKINEDMrlmrqdIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQmQVLQMKQEHQKLEENIDlikrnh 1070
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024433729 636 -------QQYSD--LLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHS 692
Cdd:TIGR00606 1071 vlalgrqKGYEKeiKHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHS 1136
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
67-320 |
1.35e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 43.49 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 67 LRDYEIQIVKLRSEFEKGEAIRqslEYALAiAKKDARLTVRTVEEElsdaRNKLAELQVFNEKLQQRLVETEK---TFHI 143
Cdd:PRK02224 208 LNGLESELAELDEEIERYEEQR---EQARE-TRDEADEVLEEHEER----REELETLEAEIEDLRETIAETERereELAE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 144 AQQKWKEQQQRLASEKDDILrthkDEYELllkERGELESILQKQnsalQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSA 223
Cdd:PRK02224 280 EVRDLRERLEELEEERDDLL----AEAGL---DDADAEAVEARR----EELEDRDEELRDRLEECRVAAQAHNEEAESLR 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 224 EQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEV---E 300
Cdd:PRK02224 349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELrerE 428
|
250 260
....*....|....*....|
gi 2024433729 301 NAYEREKQKAQENLEKVNRL 320
Cdd:PRK02224 429 AELEATLRTARERVEEAEAL 448
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
125-314 |
1.38e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.23 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 125 VFNEKLQQRLVETEKTfhiAQQKWKEQQQRLASEKDDILRTHKDEYellLKERGELESILQKQNSALQNLSKKMKDMELE 204
Cdd:PRK12704 24 VRKKIAEAKIKEAEEE---AKRILEEAKKEAEAIKKEALLEAKEEI---HKLRNEFEKELRERRNELQKLEKRLLQKEEN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 205 HRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQL--EENFEAERAAHLKSKfnlEITQMRIRelegalQMEKVSQ 282
Cdd:PRK12704 98 LDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELieEQLQELERISGLTAE---EAKEILLE------KVEEEAR 168
|
170 180 190
....*....|....*....|....*....|..
gi 2024433729 283 AEALSdleMIRKEFKEvenAYEREKQKAQENL 314
Cdd:PRK12704 169 HEAAV---LIKEIEEE---AKEEADKKAKEIL 194
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
128-483 |
1.40e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.96 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 128 EKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDiLRTHKDEYElllKERGELESILQKQNSALQNLSKKMKDMELEHRD 207
Cdd:pfam07888 30 ELLQNRLEECLQERAELLQAQEAANRQREKEKER-YKRDREQWE---RQRRELESRVAELKEELRQSREKHEELEEKYKE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 208 CSDL---LTRQVHKL-EYSAEQEERLKK-----------------ELEAATDRIKQLEENFEAERAAHLKSKFNLEITQM 266
Cdd:pfam07888 106 LSASseeLSEEKDALlAQRAAHEARIREleediktltqrvleretELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEE 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 267 RIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENlekvNRLEREYISTNKQMNEKIEEKKEIIKDLS 346
Cdd:pfam07888 186 ELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAEN----EALLEELRSLQERLNASERKVEGLGEELS 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 347 ERLQENEKIHRELqdklatakkHQVFVtetyENNMIELKLLLDSFAMSGQRtAGTCKDKdkpsslsvlETLRYTLTAYQN 426
Cdd:pfam07888 262 SMAAQRDRTQAEL---------HQARL----QAAQLTLQLADASLALREGR-ARWAQER---------ETLQQSAEADKD 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024433729 427 KLEDTSNELKKMNAL-----CENTTKELEISRDKMCVLSQ------DLKEARDKLANANKELNHLHTE 483
Cdd:pfam07888 319 RIEKLSAELQRLEERlqeerMEREKLEVELGREKDCNRVQlsesrrELQELKASLRVAQKEKEQLQAE 386
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
109-312 |
1.77e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 109 VEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDIlrthkDEYELLLKERgelESILQKQN 188
Cdd:COG3883 21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEI-----AEAEAEIEER---REELGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 189 SALQNLSKKMKDME--LEHRDCSDLLTRqVHKLEYSAEQE-------ERLKKELEAATDRIKQLEENFEAERAAHLKSKF 259
Cdd:COG3883 93 RALYRSGGSVSYLDvlLGSESFSDFLDR-LSALSKIADADadlleelKADKAELEAKKAELEAKLAELEALKAELEAAKA 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2024433729 260 NLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQE 312
Cdd:COG3883 172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
60-259 |
1.83e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 60 IIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEK 139
Cdd:COG4942 78 LAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 140 TfhiaQQKWKEQQQRLASEKDDILRTHKDeyelLLKERGELESILQKQNSALQNLSKKMKDMELEhrdcsdlltrqvhkL 219
Cdd:COG4942 158 D----LAELAALRAELEAERAELEALLAE----LEEERAALEALKAERQKLLARLEKELAELAAE--------------L 215
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2024433729 220 EYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKF 259
Cdd:COG4942 216 AELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
211-690 |
2.21e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.70 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 211 LLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENF--EAERAAHLKSKFNleITQMRIRELEGALQMEKVSQAEALSD 288
Cdd:TIGR04523 27 IANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLnkDEEKINNSNNKIK--ILEQQIKDLNDKLKKNKDKINKLNSD 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 289 LEMIRKEFK---------EVE-NAYEREKQKAQENLEKVN----RLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEK 354
Cdd:TIGR04523 105 LSKINSEIKndkeqknklEVElNKLEKQKKENKKNIDKFLteikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLN 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 355 IHRELQD--KLATAKKHQVFVTETY--ENNMIELKLLldsfAMSGQRTAGTCKDKDKPSSLSVLETLrytLTAYQNKLED 430
Cdd:TIGR04523 185 IQKNIDKikNKLLKLELLLSNLKKKiqKNKSLESQIS----ELKKQNNQLKDNIEKKQQEINEKTTE---ISNTQTQLNQ 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 431 TSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKElnhlhtecaDKAALIGTLQMELQNVQQRWEEEKV 510
Cdd:TIGR04523 258 LKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ---------KEQDWNKELKSELKNQEKKLEEIQN 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 511 RAAESENEIQKLTRAYKKDMEEKLTflhglyqhlvagcvliKQPEGildrfswSELCAVLQENVDALILDLNRANEKISH 590
Cdd:TIGR04523 329 QISQNNKIISQLNEQISQLKKELTN----------------SESEN-------SEKQRELEEKQNEIEKLKKENQSYKQE 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 591 LEYICKSKSDTMKELQRsQEDDMSKMAEQMKAQescwQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEK---ICVLE 667
Cdd:TIGR04523 386 IKNLESQINDLESKIQN-QEKLNQQKDEQIKKL----QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKeliIKNLD 460
|
490 500 510
....*....|....*....|....*....|
gi 2024433729 668 KRQEEL-----ALENLY--VKNTLTQIQKE 690
Cdd:TIGR04523 461 NTRESLetqlkVLSRSInkIKQNLEQKQKE 490
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
144-368 |
2.52e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 144 AQQKWKEQQQRLASEKDDIlRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMElehrdcsdlltrqvhkleysa 223
Cdd:COG4942 18 QADAAAEAEAELEQLQQEI-AELEKELAALKKEEKALLKQLAALERRIAALARRIRALE--------------------- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 224 EQEERLKKELEAATDRIKQLEENFEAERAA-----------HLKSKFNLEITQMRIRELEGALQ-MEKVSQA--EALSDL 289
Cdd:COG4942 76 QELAALEAELAELEKEIAELRAELEAQKEElaellralyrlGRQPPLALLLSPEDFLDAVRRLQyLKYLAPArrEQAEEL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024433729 290 EMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKK 368
Cdd:COG4942 156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
48-689 |
2.52e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.73 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 48 KLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLeYALAIAKKDARLTVRTVEEELSDARNKLAELQVFN 127
Cdd:TIGR00606 183 RYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQI-TSKEAQLESSREIVKSYENELDPLKNRLKEIEHNL 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 128 EK----------LQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKK 197
Cdd:TIGR00606 262 SKimkldneikaLKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 198 MKDMELEHRDCSDLLTR-QVHKLEYSAE-QEERLKKELE-----AATDR-------IKQLEENFEAERAAHLKSKF--NL 261
Cdd:TIGR00606 342 KTELLVEQGRLQLQADRhQEHIRARDSLiQSLATRLELDgfergPFSERqiknfhtLVIERQEDEAKTAAQLCADLqsKE 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 262 EITQMRIRELE-------GALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQE---NLEKVNRLEREYISTNKQM 331
Cdd:TIGR00606 422 RLKQEQADEIRdekkglgRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQElrkAERELSKAEKNSLTETLKK 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 332 NEKIEEKKEIIKDLSERL--QENEKIHRE---LQDKLATAKKHQVFVTETYENN---MIELKLLLDSFAmsgqrtagtck 403
Cdd:TIGR00606 502 EVKSLQNEKADLDRKLRKldQEMEQLNHHtttRTQMEMLTKDKMDKDEQIRKIKsrhSDELTSLLGYFP----------- 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 404 dkDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEA-------------RDKL 470
Cdd:TIGR00606 571 --NKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVcgsqdeesdlerlKEEI 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 471 ANANKELNHLHTECADKAALIGTLQMELQN---VQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAG 547
Cdd:TIGR00606 649 EKSSKQRAMLAGATAVYSQFITQLTDENQSccpVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEM 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 548 CVLIKQPEGILDRFSwSELcAVLQENVDALILDLNRANEKISHLEY-------------ICKSKSDTMKELQRSQEDDMS 614
Cdd:TIGR00606 729 LGLAPGRQSIIDLKE-KEI-PELRNKLQKVNRDIQRLKNDIEEQETllgtimpeeesakVCLTDVTIMERFQMELKDVER 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 615 KMAEQMKAQESC------WQKQKKYLEQQYSdlLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQ 688
Cdd:TIGR00606 807 KIAQQAAKLQGSdldrtvQQVNQEKQEKQHE--LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ 884
|
.
gi 2024433729 689 K 689
Cdd:TIGR00606 885 Q 885
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
43-361 |
2.70e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 42.65 E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 43 EDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAE 122
Cdd:TIGR00618 534 EQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACE 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 123 LQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDM- 201
Cdd:TIGR00618 614 QHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLt 693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 202 -ELEHRDCSDLLTRQVHK--LEYSAEQEE------RLKKELEAATDRIKQLEENFEAERAAHLKSKFN-----------L 261
Cdd:TIGR00618 694 yWKEMLAQCQTLLRELEThiEEYDREFNEienassSLGSDLAAREDALNQSLKELMHQARTVLKARTEahfnnneevtaA 773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 262 EITQMRIRELEGALQMEKVSQAEALSDL----EMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEE 337
Cdd:TIGR00618 774 LQTGAELSHLAAEIQFFNRLREEDTHLLktleAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLK 853
|
330 340
....*....|....*....|....
gi 2024433729 338 KKEIIKDLSERLQENEKIHRELQD 361
Cdd:TIGR00618 854 YEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
115-523 |
2.81e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 42.40 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 115 DARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESilqkqnsalqnl 194
Cdd:pfam05483 187 DLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKEN------------ 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 195 skKMKDMEL---EHRDCSDLLTR----QVHKLEYSAEQEERLKKELE---------------------AATDRIKQLEEN 246
Cdd:pfam05483 255 --KMKDLTFlleESRDKANQLEEktklQDENLKELIEKKDHLTKELEdikmslqrsmstqkaleedlqIATKTICQLTEE 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 247 FEAE-------RAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEM-IRKEFKEVE--NAYEREKQKAQENLEK 316
Cdd:pfam05483 333 KEAQmeelnkaKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMeLQKKSSELEemTKFKNNKEVELEELKK 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 317 VNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIEL------------ 384
Cdd:pfam05483 413 ILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELekeklknielta 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 385 ---KLLLDSFAMSG------------QRTAGTCKdKDKPSSLSVLETLRYTLTAYQNKLEDTSNELK--------KMNAL 441
Cdd:pfam05483 493 hcdKLLLENKELTQeasdmtlelkkhQEDIINCK-KQEERMLKQIENLEEKEMNLRDELESVREEFIqkgdevkcKLDKS 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 442 CENTTK---ELEISRDKMCVLSQDLKEARDKLANANKELNHLHTE--------CADKAAL------IGTLQMELQNVQQR 504
Cdd:pfam05483 572 EENARSieyEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEnkalkkkgSAENKQLnayeikVNKLELELASAKQK 651
|
490
....*....|....*....
gi 2024433729 505 WeEEKVRAAESENEIQKLT 523
Cdd:pfam05483 652 F-EEIIDNYQKEIEDKKIS 669
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
939-1120 |
3.53e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 42.37 E-value: 3.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 939 LQKQIAEFTQRLHTVEVERCslrrelaEFKLNFSKMKQEADKAQSLKEQLSLFKQSKliahkrfesacEELNNaLHWEHQ 1018
Cdd:COG5022 904 LESEIIELKKSLSSDLIENL-------EFKTELIARLKKLLNNIDLEEGPSIEYVKL-----------PELNK-LHEVES 964
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1019 AqvlLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRL---SEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKeSIHD 1095
Cdd:COG5022 965 K---LKETSEEYEDLLKKSTILVREGNKANSELKNFKKELaelSKQYGALQESTKQLKELPVEVAELQSASKIIS-SEST 1040
|
170 180
....*....|....*....|....*
gi 2024433729 1096 AESALcmaAKDRELIINQMKSVEAT 1120
Cdd:COG5022 1041 ELSIL---KPLQKLKGLLLLENNQL 1062
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
180-690 |
4.26e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.81 E-value: 4.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 180 LESILQKQNSALQNLSKKMKDMELEHRDcsdlLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEEnfeaeraahLKSKF 259
Cdd:PRK01156 188 LEEKLKSSNLELENIKKQIADDEKSHSI----TLKEIERLSIEYNNAMDDYNNLKSALNELSSLED---------MKNRY 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 260 NLEitqmrIRELEGALQMEkvsqaealsdlEMIRKEFKEVENAYER-EKQKAQENLEKVNrlerEYISTNKQMnekiEEK 338
Cdd:PRK01156 255 ESE-----IKTAESDLSME-----------LEKNNYYKELEERHMKiINDPVYKNRNYIN----DYFKYKNDI----ENK 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 339 KEIIKDLSERLQENEKIHRELQDklatakkhqvfvTETYENNMIELKllldsfamsgqrtagtcKDKDKpsslsvLETLR 418
Cdd:PRK01156 311 KQILSNIDAEINKYHAIIKKLSV------------LQKDYNDYIKKK-----------------SRYDD------LNNQI 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 419 YTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKmcvLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMEL 498
Cdd:PRK01156 356 LELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAF---ISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRI 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 499 QNVQQRWEEekvraaeseneiqkltraykkdMEEKLTFLHGLYQHLVAGCVLikQPEGILD-RFSWSELCAVLQENVDAL 577
Cdd:PRK01156 433 RALRENLDE----------------------LSRNMEMLNGQSVCPVCGTTL--GEEKSNHiINHYNEKKSRLEEKIREI 488
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 578 ILDLNRANEKISHL----EYICKSK-------SDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKY-------LEQQYS 639
Cdd:PRK01156 489 EIEVKDIDEKIVDLkkrkEYLESEEinksineYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYkslkledLDSKRT 568
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024433729 640 DLLGEVHARAQEYKETAEKNKE----KICVLEKRQEELALE----NLYVKNTLTQIQKE 690
Cdd:PRK01156 569 SWLNALAVISLIDIETNRSRSNeikkQLNDLESRLQEIEIGfpddKSYIDKSIREIENE 627
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
184-364 |
4.52e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 41.65 E-value: 4.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 184 LQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAatdRIKQLEENfEAERAAHLKSKFNLEI 263
Cdd:pfam05557 4 LIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQK---RIRLLEKR-EAEAEEALREQAELNR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 264 TQMRIRELEGALQMEKVSQAEALSDLEM-IRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEII 342
Cdd:pfam05557 80 LKKKYLEALNKKLNEKESQLADAREVIScLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLE 159
|
170 180
....*....|....*....|..
gi 2024433729 343 KDLSERLQENEKIhRELQDKLA 364
Cdd:pfam05557 160 KQQSSLAEAEQRI-KELEFEIQ 180
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
37-318 |
6.72e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.16 E-value: 6.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 37 SELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDA 116
Cdd:TIGR04523 412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 117 RNKLAELQVFNEKLQQrLVETEKTFHIAQQKWKEQQQRLASEKDDI---LRTHKDEYELL--LKERGELESILQKQNSAL 191
Cdd:TIGR04523 492 KSKEKELKKLNEEKKE-LEEKVKDLTKKISSLKEKIEKLESEKKEKeskISDLEDELNKDdfELKKENLEKEIDEKNKEI 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 192 QNLSKKMKDMELEHRDCSDLLTrqvhklEYSAEQEErLKKELEAATDRIKQLEENFEAERAAHLKskfnLEITQMRIREL 271
Cdd:TIGR04523 571 EELKQTQKSLKKKQEEKQELID------QKEKEKKD-LIKEIEEKEKKISSLEKELEKAKKENEK----LSSIIKNIKSK 639
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2024433729 272 EGALQMEkvsqaealsdLEMIRKEFKEVENAYEREKQKAQENLEKVN 318
Cdd:TIGR04523 640 KNKLKQE----------VKQIKETIKEIRNKWPEIIKKIKESKTKID 676
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
934-1093 |
6.79e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 6.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 934 KSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKlnfSKMKQEADKAQSLKEQLSLFKQSKliahkrfesaceELNNAL 1013
Cdd:COG1579 31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLE---LEIEEVEARIKKYEEQLGNVRNNK------------EYEALQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1014 HWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELrrkDQSLRQLNRLLTQLEQDKRRLKESI 1093
Cdd:COG1579 96 KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL---DEELAELEAELEELEAEREELAAKI 172
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
454-662 |
6.93e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.58 E-value: 6.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 454 DKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKdmeek 533
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE----- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 534 ltFLHGLYQHLVAGCVLI-----KQPEGILDRFSwseLCAVLQENVDALILDLNRANEKISHLeyicKSKSDTMKELQRS 608
Cdd:COG3883 91 --RARALYRSGGSVSYLDvllgsESFSDFLDRLS---ALSKIADADADLLEELKADKAELEAK----KAELEAKLAELEA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2024433729 609 QEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEK 662
Cdd:COG3883 162 LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
941-1097 |
7.38e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 7.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 941 KQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHK------RFESACEELNNALH 1014
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAElaelpeRLEELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 1015 WEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKdqsLRQLNRLLTQLEQDKRRLKESIH 1094
Cdd:COG4717 161 LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEE---LEEAQEELEELEEELEQLENELE 237
|
...
gi 2024433729 1095 DAE 1097
Cdd:COG4717 238 AAA 240
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
174-533 |
8.96e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.65 E-value: 8.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 174 LKERGELesiLQKQNSALQNLSKKmkdmELEHRDCSDLLTRQVHKLEysaEQEERLKKELEAATDRIKQLEENFEAERAA 253
Cdd:pfam07888 40 LQERAEL---LQAQEAANRQREKE----KERYKRDREQWERQRRELE---SRVAELKEELRQSREKHEELEEKYKELSAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 254 H--LKSKFNL-----EITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVeNAYEREKQKAQENLE-KVNRLEREYI 325
Cdd:pfam07888 110 SeeLSEEKDAllaqrAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKA-GAQRKEEEAERKQLQaKLQQTEEELR 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 326 STNKQMNEKIEEKKEIIkdlSERLQENEKIHReLQDKLATAKKHQVfvtetyENNmielkllldsfamsgqrtagtckdk 405
Cdd:pfam07888 189 SLSKEFQELRNSLAQRD---TQVLQLQDTITT-LTQKLTTAHRKEA------ENE------------------------- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 406 dkpSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANkelnhlhteca 485
Cdd:pfam07888 234 ---ALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGR----------- 299
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 2024433729 486 dkaaliGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEK 533
Cdd:pfam07888 300 ------ARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMER 341
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
76-693 |
9.29e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 40.81 E-value: 9.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 76 KLRSEFEKGeaIRQSleYALAIAKKDARLTVRTVEEELSDARNKLaELQVfNEKLQQRLVETEKTFHIAQQKWkEQQQRL 155
Cdd:TIGR01612 537 KLYKEIEAG--LKES--YELAKNWKKLIHEIKKELEEENEDSIHL-EKEI-KDLFDKYLEIDDEIIYINKLKL-ELKEKI 609
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 156 ASEKDdilrthKDEYellLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVhKLEYSAEQEERLKKELEA 235
Cdd:TIGR01612 610 KNISD------KNEY---IKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTI-KSELSKIYEDDIDALYNE 679
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 236 ATDRIKQLE-ENFEAE-RAAHLKSKFNLEITQMRIRELEGA------------------LQMEKVSQAEALSDLEMIRKE 295
Cdd:TIGR01612 680 LSSIVKENAiDNTEDKaKLDDLKSKIDKEYDKIQNMETATVelhlsnienkknelldiiVEIKKHIHGEINKDLNKILED 759
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 296 FKEVE-------NAYEREKQKAQENLEKVNRLEREYistNKQMNEKIEEKKEIIKD----------LSERLQENEKIHRE 358
Cdd:TIGR01612 760 FKNKEkelsnkiNDYAKEKDELNKYKSKISEIKNHY---NDQINIDNIKDEDAKQNydkskeyiktISIKEDEIFKIINE 836
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 359 LQD-KLATAKKHQVFVTetYENNMIE-LKLLLDSFAMSGQRTAGTCKD-------KDKPSSLSVL-ETLRYTLTAYQNkl 428
Cdd:TIGR01612 837 MKFmKDDFLNKVDKFIN--FENNCKEkIDSEHEQFAELTNKIKAEISDdklndyeKKFNDSKSLInEINKSIEEEYQN-- 912
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 429 edtSNELKKMNA---LCENTTKELEISRDKMCVLSQDLKEARDKLANANKelnhlhTECADKAALIGTLQMELQNVQQRW 505
Cdd:TIGR01612 913 ---INTLKKVDEyikICENTKESIEKFHNKQNILKEILNKNIDTIKESNL------IEKSYKDKFDNTLIDKINELDKAF 983
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 506 EEEKVRAAESE-NEIQKltraYKKDMEEKL------TFLHGLYQHLVAGCVLIKQPEGILDRFSWSELC----------- 567
Cdd:TIGR01612 984 KDASLNDYEAKnNELIK----YFNDLKANLgknkenMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAihtsiyniide 1059
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 568 --AVLQENVDAL-----------ILDLNRANEKISHLEYickskSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYL 634
Cdd:TIGR01612 1060 ieKEIGKNIELLnkeileeaeinITNFNEIKEKLKHYNF-----DDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKAL 1134
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024433729 635 EQ---QYSDLLGEVHARAQEYKETAEK--NKEKICVLEKRQEELAL-----ENLY-----VKNTLTQIQKEHSS 693
Cdd:TIGR01612 1135 EEikkKSENYIDEIKAQINDLEDVADKaiSNDDPEEIEKKIENIVTkidkkKNIYdeikkLLNEIAEIEKDKTS 1208
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
73-364 |
9.83e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 40.27 E-value: 9.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 73 QIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQ 152
Cdd:COG4372 7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 153 QRLASEKDDILRThKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKE 232
Cdd:COG4372 87 EQLQAAQAELAQA-QEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024433729 233 LEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQE 312
Cdd:COG4372 166 LAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELE 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2024433729 313 NLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLA 364
Cdd:COG4372 246 EDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKL 297
|
|
| |
