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Conserved domains on  [gi|528961268|ref|XP_005211097|]
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protein-L-isoaspartate(D-aspartate) O-methyltransferase isoform X2 [Bos taurus]

Protein Classification

protein-L-isoaspartate O-methyltransferase( domain architecture ID 12014395)

protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-274 1.44e-113

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


:

Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 325.86  E-value: 1.44e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKAL 141
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMHAMMLELL--ELKPGMRVL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  142 DVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKDDPMllssgRVQLVVGDGRMGYAAEAPYDAIHVGAAAP 221
Cdd:pfam01135  79 EIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAP 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 528961268  222 VVPQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 274
Cdd:pfam01135 154 EIPEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
 
Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-274 1.44e-113

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 325.86  E-value: 1.44e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKAL 141
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMHAMMLELL--ELKPGMRVL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  142 DVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKDDPMllssgRVQLVVGDGRMGYAAEAPYDAIHVGAAAP 221
Cdd:pfam01135  79 EIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAP 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 528961268  222 VVPQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 274
Cdd:pfam01135 154 EIPEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 62-281 5.90e-72

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 220.47  E-value: 5.90e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268   62 KSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEG 137
Cdd:TIGR00080   1 MDLESQKKALIDKLINEGYIKSKRVIDALLSVPREEFVpehfKEYAYVDTPLEIGYGQTISAPHMVAMMTELL--ELKPG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  138 AKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAIHVG 217
Cdd:TIGR00080  79 MKVLEIGTGSGYQAAVLAEIVGRDGLVVSIERIPELAEKAERRLRK-----LGLDNVIVIVGDGTQGWEPLAPYDRIYVT 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 528961268  218 AAAPVVPQALIDQLKPGGRLILPVGPagGNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKEKQW 281
Cdd:TIGR00080 154 AAGPKIPEALIDQLKEGGILVMPVGE--YLQVLKRAEK-RGGEIIIKDVEPVAFVPLVGGEGFQ 214
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 70-278 2.25e-52

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 170.20  E-value: 2.25e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  70 ELIHNLRKNGIIKTDKVFEVMLATDR----SHYAKCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKALDVGS 145
Cdd:PRK13942   8 RVIEELIREGYIKSKKVIDALLKVPRhlfvPEYLEEYAYVDTPLEIGYGQTISAIHMVAIMCELL--DLKEGMKVLEIGT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 146 GSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQ 225
Cdd:PRK13942  86 GSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTLKK-----LGYDNVEVIVGDGTLGYEENAPYDRIYVTAAGPDIPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 528961268 226 ALIDQLKPGGRLILPVGPAggNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK13942 161 PLIEQLKDGGIMVIPVGSY--SQELIRVEK-DNGKIIKKKLGEVAFVPLIGKN 210
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 75-275 3.24e-50

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 164.11  E-value: 3.24e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  75 LRKNGIiKTDKVFEVMLATDR--------SHYAkcnpYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKALDVGSG 146
Cdd:COG2518    4 LRPRGV-TDPRVLDAMRAVPRelfvpealRELA----YADRALPIGHGQTISQPYIVARMLEAL--DLKPGDRVLEIGTG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 147 SGILTACFARMVGpsgKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQA 226
Cdd:COG2518   77 SGYQAAVLARLAG---RVYSVERDPELAERARERLAA-----LGYDNVTVRVGDGALGWPEHAPFDRIIVTAAAPEVPEA 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 528961268 227 LIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGsVKMKPLMGVIYVPLT 275
Cdd:COG2518  149 LLEQLAPGGRLVAPVGE-GGVQRLVLITRTGDG-FERESLFEVRFVPLR 195
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 139-241 6.41e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 47.04  E-value: 6.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 139 KALDVGSGSGILTACFARmvGPSGKVIGIDhikelVDDSINNVRKDDPMLLSSGRVQLVVGDGRMG-YAAEAPYDAIHVG 217
Cdd:cd02440    1 RVLDLGCGTGALALALAS--GPGARVTGVD-----ISPVALELARKAAAALLADNVEVLKGDAEELpPEADESFDVIISD 73

                         90       100       110
                 ....*....|....*....|....*....|.
gi 528961268 218 AAAPVV---PQALIDQ----LKPGGRLILPV 241
Cdd:cd02440   74 PPLHHLvedLARFLEEarrlLKPGGVLVLTL 104
 
Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-274 1.44e-113

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 325.86  E-value: 1.44e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKAL 141
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMHAMMLELL--ELKPGMRVL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  142 DVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKDDPMllssgRVQLVVGDGRMGYAAEAPYDAIHVGAAAP 221
Cdd:pfam01135  79 EIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAP 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 528961268  222 VVPQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 274
Cdd:pfam01135 154 EIPEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 62-281 5.90e-72

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 220.47  E-value: 5.90e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268   62 KSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEG 137
Cdd:TIGR00080   1 MDLESQKKALIDKLINEGYIKSKRVIDALLSVPREEFVpehfKEYAYVDTPLEIGYGQTISAPHMVAMMTELL--ELKPG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  138 AKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAIHVG 217
Cdd:TIGR00080  79 MKVLEIGTGSGYQAAVLAEIVGRDGLVVSIERIPELAEKAERRLRK-----LGLDNVIVIVGDGTQGWEPLAPYDRIYVT 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 528961268  218 AAAPVVPQALIDQLKPGGRLILPVGPagGNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKEKQW 281
Cdd:TIGR00080 154 AAGPKIPEALIDQLKEGGILVMPVGE--YLQVLKRAEK-RGGEIIIKDVEPVAFVPLVGGEGFQ 214
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 70-278 2.25e-52

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 170.20  E-value: 2.25e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  70 ELIHNLRKNGIIKTDKVFEVMLATDR----SHYAKCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKALDVGS 145
Cdd:PRK13942   8 RVIEELIREGYIKSKKVIDALLKVPRhlfvPEYLEEYAYVDTPLEIGYGQTISAIHMVAIMCELL--DLKEGMKVLEIGT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 146 GSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQ 225
Cdd:PRK13942  86 GSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTLKK-----LGYDNVEVIVGDGTLGYEENAPYDRIYVTAAGPDIPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 528961268 226 ALIDQLKPGGRLILPVGPAggNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK13942 161 PLIEQLKDGGIMVIPVGSY--SQELIRVEK-DNGKIIKKKLGEVAFVPLIGKN 210
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 75-275 3.24e-50

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 164.11  E-value: 3.24e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  75 LRKNGIiKTDKVFEVMLATDR--------SHYAkcnpYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKALDVGSG 146
Cdd:COG2518    4 LRPRGV-TDPRVLDAMRAVPRelfvpealRELA----YADRALPIGHGQTISQPYIVARMLEAL--DLKPGDRVLEIGTG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 147 SGILTACFARMVGpsgKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQA 226
Cdd:COG2518   77 SGYQAAVLARLAG---RVYSVERDPELAERARERLAA-----LGYDNVTVRVGDGALGWPEHAPFDRIIVTAAAPEVPEA 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 528961268 227 LIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGsVKMKPLMGVIYVPLT 275
Cdd:COG2518  149 LLEQLAPGGRLVAPVGE-GGVQRLVLITRTGDG-FERESLFEVRFVPLR 195
pcm PRK00312
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
71-278 1.14e-45

protein-L-isoaspartate(D-aspartate) O-methyltransferase;


Pssm-ID: 178974 [Multi-domain]  Cd Length: 212  Bit Score: 153.05  E-value: 1.14e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  71 LIHNLRKNGIiKTDKVFEVMLATDRS--------HYAkcnpYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKALD 142
Cdd:PRK00312  12 LVLRLRAEGI-LDERVLEAIEATPRElfvpeafkHKA----YENRALPIGCGQTISQPYMVARMTELL--ELKPGDRVLE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 143 VGSGSGILTACFARMVGpsgKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPV 222
Cdd:PRK00312  85 IGTGSGYQAAVLAHLVR---RVFSVERIKTLQWEAKRRLKQ-----LGLHNVSVRHGDGWKGWPAYAPFDRILVTAAAPE 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 528961268 223 VPQALIDQLKPGGRLILPVGpaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK00312 157 IPRALLEQLKEGGILVAPVG--GEEQQLLTRVRKRGGRFEREVLEEVRFVPLVKGE 210
PRK13944 PRK13944
protein-L-isoaspartate O-methyltransferase; Provisional
 71-274 2.42e-32

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 140001  Cd Length: 205  Bit Score: 118.38  E-value: 2.42e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  71 LIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLNEGAKALDVGSG 146
Cdd:PRK13944   5 LVEELVREGIIKSERVKKAMLSVPREEFVmpeyRMMAYEDRPLPLFAGATISAPHMVAMMCELI--EPRPGMKILEVGTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 147 SGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmLLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQA 226
Cdd:PRK13944  83 SGYQAAVCAEAIERRGKVYTVEIVKELAIYAAQNIER----LGYWGVVEVYHGDGKRGLEKHAPFDAIIVTAAASTIPSA 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 528961268 227 LIDQLKPGGRLILPVGPAGGnQMLEQYDKLQDGsVKMKPLMGVIYVPL 274
Cdd:PRK13944 159 LVRQLKDGGVLVIPVEEGVG-QVLYKVVKRGEK-VEKRAITYVLFVPL 204
methyltran_FxLD TIGR04364
methyltransferase, FxLD system; Members of this family resemble occur regularly in the ...
 69-241 1.60e-20

methyltransferase, FxLD system; Members of this family resemble occur regularly in the vicinity of lantibiotic biosynthesis enzymes and their probable target, the FxLD family of putative ribosomal natural product precursor (TIGR04363). Members resemble protein-L-isoaspartate O-methyltransferase (TIGR00080) and a predicted methyltranserase, TIGR04188, of another putative peptide modification system.


Pssm-ID: 275158  Cd Length: 394  Bit Score: 90.12  E-value: 1.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268   69 SELIHNLRKNGIIKTDKVFEVMLATDRSHYAKCNP----YM----------DSPQSIgfqATISAPHMHAYALELLfdQL 134
Cdd:TIGR04364   6 AALVDELREDGVIRSPRVEAAFRTVPRHLFAPGAPlekaYAanravvtkrdEDGRAL---SSVSAPHIQAMMLEQA--GV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  135 NEGAKALDVGSGsGILTACFARMVGPSGKVIGIDHIKELVDDSinnvRKddpMLLSSG--RVQLVVGDGRMGYAAEAPYD 212
Cdd:TIGR04364  81 EPGMRVLEIGSG-GYNAALLAELVGPSGEVTTVDIDEDVTDRA----RA---CLAAAGypQVTVVLADAEAGVPELAPYD 152

                         170       180
                  ....*....|....*....|....*....
gi 528961268  213 AIHVGAAAPVVPQALIDQLKPGGRLILPV 241
Cdd:TIGR04364 153 RIIVTVGAWDIPPAWLDQLAPGGRLVVPL 181
PRK13943 PRK13943
protein-L-isoaspartate O-methyltransferase; Provisional
 64-241 7.40e-19

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 237568 [Multi-domain]  Cd Length: 322  Bit Score: 84.90  E-value: 7.40e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  64 GGASHSELIHNLRKNGIikTDKVFEVMLATDRS-----HYAKCNPYMD----SPQSIGFQATISAPHMHAYALELLfdQL 134
Cdd:PRK13943   3 EFFMREKLFWILKKYGI--SDHIAKAFLEVPREefltkSYPLSYVYEDivlvSYDDGEEYSTSSQPSLMALFMEWV--GL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 135 NEGAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRMGYAAEAPYDAI 214
Cdd:PRK13943  79 DKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVRR-----LGIENVIFVCGDGYYGVPEFAPYDVI 153

                        170       180
                 ....*....|....*....|....*..
gi 528961268 215 HVGAAAPVVPQALIDQLKPGGRLILPV 241
Cdd:PRK13943 154 FVTVGVDEVPETWFTQLKEGGRVIVPI 180
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 137-238 3.03e-12

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 64.80  E-value: 3.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 137 GAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmLLSSGRVQLVVGDGRMGYaAEAPYDAIHV 216
Cdd:COG2519   92 GARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLER----FGLPDNVELKLGDIREGI-DEGDVDAVFL 166

                         90       100
                 ....*....|....*....|....
gi 528961268 217 GAAAP--VVPQAlIDQLKPGGRLI 238
Cdd:COG2519  167 DMPDPweALEAV-AKALKPGGVLV 189
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
136-239 2.30e-10

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 56.37  E-value: 2.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 136 EGAKALDVGSGSGILTACFARMVgPSGKVIGIDhikeLVDDSINNVRKDDPmllssgRVQLVVGDGRmGYAAEAPYDAIH 215
Cdd:COG4106    1 PPRRVLDLGCGTGRLTALLAERF-PGARVTGVD----LSPEMLARARARLP------NVRFVVADLR-DLDPPEPFDLVV 68

                         90       100       110
                 ....*....|....*....|....*....|
gi 528961268 216 VGAA------APVVPQALIDQLKPGGRLIL 239
Cdd:COG4106   69 SNAAlhwlpdHAALLARLAAALAPGGVLAV 98
methyltr_grsp TIGR04188
methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are ...
 134-246 6.74e-10

methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).


Pssm-ID: 275041  Cd Length: 363  Bit Score: 58.91  E-value: 6.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  134 LNEGAKALDVGSGSGILTACFARMVGpSGKVIGIDHIKELVDDSinnvrkdDPMLLSSG-RVQLVVGDGRMGYAAEAPYD 212
Cdd:TIGR04188 105 VEDGHRVLEIGTGTGYSAALLCHRLG-DDNVTSVEVDPGLAARA-------ASALAAAGyAPTVVTGDGLLGHPPRAPYD 176

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 528961268  213 AIHVGAAAPVVPQALIDQLKPGGRLILPVG---PAGG 246
Cdd:TIGR04188 177 RIIATCAVRRVPPAWLRQTRPGGVILTTLSgwlYGGG 213
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 128-239 2.30e-09

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 54.25  E-value: 2.30e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 128 ELLFDQLNEGAKALDVGSGSGILTACFARMvgpsG-KVIGIDhikeLVDDSINNVRKddpmLLSSGRVQLVVGDGRMGYA 206
Cdd:COG2227   16 ALLARLLPAGGRVLDVGCGTGRLALALARR----GaDVTGVD----ISPEALEIARE----RAAELNVDFVQGDLEDLPL 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 528961268 207 AEAPYDAI-------HVGAAAPVVpQALIDQLKPGGRLIL 239
Cdd:COG2227   84 EDGSFDLVicsevleHLPDPAALL-RELARLLKPGGLLLL 122
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 126-269 6.54e-09

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 54.54  E-value: 6.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 126 ALELLFDQLNEGAKALDVGSGSGILTACFARMVGpsGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGD-GRMG 204
Cdd:COG0500   16 ALLALLERLPKGGRVLDLGCGTGRNLLALAARFG--GRVIGIDLSPEAIALARARAAK-----AGLGNVEFLVADlAELD 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528961268 205 YAAEAPYDAI-------HVgaaAPVVPQALID----QLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGV 269
Cdd:COG0500   89 PLPAESFDLVvafgvlhHL---PPEEREALLRelarALKPGGVLLLSASDAAAALSLARLLLLATASLLELLLLLR 161
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
127-239 9.18e-09

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 55.18  E-value: 9.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 127 LELLFDQLNEGAKALDVGSGSGILtACFARMVGPsGKVIGIDhIKEL-VDDSINNVRKDDpmllSSGRVQLVVGDGRmgy 205
Cdd:COG2264  139 LEALEKLLKPGKTVLDVGCGSGIL-AIAAAKLGA-KRVLAVD-IDPVaVEAARENAELNG----VEDRIEVVLGDLL--- 208

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 528961268 206 aAEAPYDAIhVgA---AAPVVPQA--LIDQLKPGGRLIL 239
Cdd:COG2264  209 -EDGPYDLV-V-AnilANPLIELApdLAALLKPGGYLIL 244
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 126-239 1.86e-08

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 52.62  E-value: 1.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 126 ALELLFDQLN--EGAKALDVGSGSGILTACFARMVGpsGKVIGIDhikeLVDDSINNVRKDDPMLLSSGRVQLVVGDGRm 203
Cdd:COG2230   39 KLDLILRKLGlkPGMRVLDIGCGWGGLALYLARRYG--VRVTGVT----LSPEQLEYARERAAEAGLADRVEVRLADYR- 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 528961268 204 GYAAEAPYDAI-------HVGAAA-PVVPQALIDQLKPGGRLIL 239
Cdd:COG2230  112 DLPADGQFDAIvsigmfeHVGPENyPAYFAKVARLLKPGGRLLL 155
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 141-235 3.91e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 50.25  E-value: 3.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  141 LDVGSGSGILTACFARMVGpsGKVIGIDHIKELVDDSINNVRKDDPmllssgRVQLVVGDGRMGYAAEAPYDAIHVGAAA 220
Cdd:pfam13649   2 LDLGCGTGRLTLALARRGG--ARVTGVDLSPEMLERARERAAEAGL------NVEFVQGDAEDLPFPDGSFDLVVSSGVL 73

                          90       100
                  ....*....|....*....|...
gi 528961268  221 PVVPQALIDQ--------LKPGG 235
Cdd:pfam13649  74 HHLPDPDLEAalreiarvLKPGG 96
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 126-239 9.24e-08

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 50.38  E-value: 9.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 126 ALELLFDQLN--EGAKALDVGSGSGILTACFARMvgpSGKVIGIDHIKELVDDSINNVRKDDPmllssgRVQLVVGDG-R 202
Cdd:COG2226   10 GREALLAALGlrPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERAAEAGL------NVEFVVGDAeD 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 528961268 203 MGYaAEAPYDAIHVGAAAPVVP--QALIDQ----LKPGGRLIL 239
Cdd:COG2226   81 LPF-PDGSFDLVISSFVLHHLPdpERALAEiarvLKPGGRLVV 122
PRK08317 PRK08317
hypothetical protein; Provisional
 124-239 1.18e-07

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 51.48  E-value: 1.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 124 AYALELLfdQLNEGAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINnvRKDDpmllSSGRVQLVVGDG-R 202
Cdd:PRK08317   9 ARTFELL--AVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALAKE--RAAG----LGPNVEFVRGDAdG 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 528961268 203 MGYAAEApYDAI-------HVGAaapvvPQALIDQ----LKPGGRLIL 239
Cdd:PRK08317  81 LPFPDGS-FDAVrsdrvlqHLED-----PARALAEiarvLRPGGRVVV 122
arsM PRK11873
arsenite methyltransferase;
131-183 4.29e-07

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 49.95  E-value: 4.29e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 528961268 131 FDQLNEGAKALDVGSGSGIltACF--ARMVGPSGKVIGIDHIKELVDDSINNVRK 183
Cdd:PRK11873  72 LAELKPGETVLDLGSGGGF--DCFlaARRVGPTGKVIGVDMTPEMLAKARANARK 124
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 134-239 5.30e-07

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 48.18  E-value: 5.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  134 LNEGAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGD-GRMGYA-AEAPY 211
Cdd:pfam13847   1 IDKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENAQK-----LGFDNVEFEQGDiEELPELlEDDKF 75

                          90       100       110
                  ....*....|....*....|....*....|....
gi 528961268  212 D------AIHVGAAAPVVPQALIDQLKPGGRLIL 239
Cdd:pfam13847  76 DvvisncVLNHIPDPDKVLQEILRVLKPGGRLII 109
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 139-241 6.41e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 47.04  E-value: 6.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 139 KALDVGSGSGILTACFARmvGPSGKVIGIDhikelVDDSINNVRKDDPMLLSSGRVQLVVGDGRMG-YAAEAPYDAIHVG 217
Cdd:cd02440    1 RVLDLGCGTGALALALAS--GPGARVTGVD-----ISPVALELARKAAAALLADNVEVLKGDAEELpPEADESFDVIISD 73

                         90       100       110
                 ....*....|....*....|....*....|.
gi 528961268 218 AAAPVV---PQALIDQ----LKPGGRLILPV 241
Cdd:cd02440   74 PPLHHLvedLARFLEEarrlLKPGGVLVLTL 104
CbiT TIGR02469
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes ...
 117-241 6.77e-07

precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes the CbiT methylase which is responsible, in part (along with CbiE), for methylating precorrin-6y (or cobalt-precorrin-6y) at both the 5 and 15 positions as well as the concomitant decarbozylation at C-12. In many organisms, this protein is fused to the CbiE subunit. The fused protein, when found in organisms catalyzing the oxidative version of the cobalamin biosynthesis pathway, is called CobL. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 274148 [Multi-domain]  Cd Length: 124  Bit Score: 47.32  E-value: 6.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  117 ISAPHMHAYALELLfdQLNEGAKALDVGSGSGILTACFARMVgPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQL 196
Cdd:TIGR02469   2 MTKREVRALTLAKL--RLRPGDVLWDIGAGTGSVTIEAARLV-PNGRVYAIERNPEALDLIERNLRR-----FGVSNIVI 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 528961268  197 VVGDgrmgyAAEAPY------DAIHVGAAA---PVVPQALIDQLKPGGRLILPV 241
Cdd:TIGR02469  74 VEGD-----APEAPEallpdpDAVFVGGSGgllQEILEAVERRLRPGGRIVLNA 122
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 137-239 3.71e-06

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 47.07  E-value: 3.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 137 GAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDdsinNVRKDDPMLLSSGRVQLVVGDgrmgyAAEAPY----- 211
Cdd:PRK00216  52 GDKVLDLACGTGDLAIALAKAVGKTGEVVGLDFSEGMLA----VGREKLRDLGLSGNVEFVQGD-----AEALPFpdnsf 122

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 528961268 212 DAIHVGAAAPVVPQalIDQ--------LKPGGRL-IL 239
Cdd:PRK00216 123 DAVTIAFGLRNVPD--IDKalremyrvLKPGGRLvIL 157
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
127-239 3.07e-05

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 44.37  E-value: 3.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 127 LELLFDQLNEGAKALDVGSGSGILtACFARMVGPsGKVIGIDhIKEL-VDDSINNVRkddpmlLSSGRVQLVVGDGrmgy 205
Cdd:PRK00517 110 LEALEKLVLPGKTVLDVGCGSGIL-AIAAAKLGA-KKVLAVD-IDPQaVEAARENAE------LNGVELNVYLPQG---- 176

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 528961268 206 aaEAPYDAIhVgA---AAPVVpqALIDQ----LKPGGRLIL 239
Cdd:PRK00517 177 --DLKADVI-V-AnilANPLL--ELAPDlarlLKPGGRLIL 211
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
136-238 5.89e-05

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 43.20  E-value: 5.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  136 EGAKALDVGSGSGILTACFARMVGPSGKVIGIDhikelvddsINnvrkddPMLLSSGR----------VQLVVGDGRMGY 205
Cdd:pfam01209  42 RGNKFLDVAGGTGDWTFGLSDSAGSSGKVVGLD---------IN------ENMLKEGEkkakeegkynIEFLQGNAEELP 106

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 528961268  206 AAEAPYDAIHVGAA---APVVPQALIDQ---LKPGGRLI 238
Cdd:pfam01209 107 FEDDSFDIVTISFGlrnFPDYLKVLKEAfrvLKPGGRVV 145
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 139-235 6.53e-05

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 42.48  E-value: 6.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 139 KALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKDDpmllSSGRVQLVVGDGR--MGYAAEAPYDAIHV 216
Cdd:COG4122   19 RILEIGTGTGYSTLWLARALPDDGRLTTIEIDPERAAIARENFARAG----LADRIRLILGDALevLPRLADGPFDLVFI 94

                         90       100
                 ....*....|....*....|..
gi 528961268 217 GAAAPVVP---QALIDQLKPGG 235
Cdd:COG4122   95 DADKSNYPdylELALPLLRPGG 116
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 126-241 1.32e-04

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 42.09  E-value: 1.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 126 ALELLFDQLNEGAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKDDPMllssGRVQLVVGDGRMGY 205
Cdd:PRK00377  30 ALALSKLRLRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRRNAEKFGVL----NNIVLIKGEAPEIL 105

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 528961268 206 AAEAP-YDAIHVGAAA---PVVPQALIDQLKPGGRLILPV 241
Cdd:PRK00377 106 FTINEkFDRIFIGGGSeklKEIISASWEIIKKGGRIVIDA 145
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 128-239 1.34e-04

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 41.71  E-value: 1.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 128 ELLFDQL--NEGAKALDVGSGSGILTACFARMvGPSGKVIGIDhIKEL-VDDSINNVRKDDPmllssGRVQLVVGDGRMG 204
Cdd:COG2813   39 RLLLEHLpePLGGRVLDLGCGYGVIGLALAKR-NPEARVTLVD-VNARaVELARANAAANGL-----ENVEVLWSDGLSG 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 528961268 205 yAAEAPYDAI------HVGAAAPV-VPQALIDQ----LKPGGRLIL 239
Cdd:COG2813  112 -VPDGSFDLIlsnppfHAGRAVDKeVAHALIADaarhLRPGGELWL 156
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 141-239 1.57e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 39.96  E-value: 1.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  141 LDVGSGSGILTACFARMVgpsGKVIGIDHIKELVDDSINNVRKDDpmllssgrVQLVVGDG-RMGYAAEApYDAIHVGAA 219
Cdd:pfam08241   1 LDVGCGTGLLTELLARLG---ARVTGVDISPEMLELAREKAPREG--------LTFVVGDAeDLPFPDNS-FDLVLSSEV 68

                          90       100
                  ....*....|....*....|....*.
gi 528961268  220 A---PVVPQAL--IDQ-LKPGGRLIL 239
Cdd:pfam08241  69 LhhvEDPERALreIARvLKPGGILII 94
PLN02366 PLN02366
spermidine synthase
 139-235 2.97e-04

spermidine synthase


Pssm-ID: 215208 [Multi-domain]  Cd Length: 308  Bit Score: 41.55  E-value: 2.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 139 KALDVGSGSGILTACFARMvgPSGKVIGIDHIKELVDDSINN------VRKDDPmllssgRVQLVVGDGR--MGYAAEAP 210
Cdd:PLN02366  94 KVLVVGGGDGGVLREIARH--SSVEQIDICEIDKMVIDVSKKffpdlaVGFDDP------RVNLHIGDGVefLKNAPEGT 165

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 528961268 211 YDAIHVGAAAPVVP-QALIDQ---------LKPGG 235
Cdd:PLN02366 166 YDAIIVDSSDPVGPaQELFEKpffesvaraLRPGG 200
PRK14968 PRK14968
putative methyltransferase; Provisional
 128-168 4.45e-04

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 40.27  E-value: 4.45e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 528961268 128 ELLFDQL--NEGAKALDVGSGSGILTACFARMvgpSGKVIGID 168
Cdd:PRK14968  13 FLLAENAvdKKGDRVLEVGTGSGIVAIVAAKN---GKKVVGVD 52
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
121-239 1.10e-03

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 39.21  E-value: 1.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 121 HMHAYALELLFDQlnEGAKALDVGSGSGILTACFARMVgpsGKVIGIDhikeLVDDSINNVRKddpmllSSGRVQLVVGD 200
Cdd:COG4976   33 LLAEELLARLPPG--PFGRVLDLGCGTGLLGEALRPRG---YRLTGVD----LSEEMLAKARE------KGVYDRLLVAD 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 528961268 201 GRMGYAAEAPYDAI-------HVGAAAPVVpQALIDQLKPGGRLIL 239
Cdd:COG4976   98 LADLAEPDGRFDLIvaadvltYLGDLAAVF-AGVARALKPGGLFIF 142
PRK08287 PRK08287
decarboxylating cobalt-precorrin-6B (C(15))-methyltransferase;
124-239 3.68e-03

decarboxylating cobalt-precorrin-6B (C(15))-methyltransferase;


Pssm-ID: 181354  Cd Length: 187  Bit Score: 37.67  E-value: 3.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268 124 AYALELLfdQLNEGAKALDVGSGSGILTACFARMVgPSGKVIGIDHIKELVDDSINNVRKddpmlLSSGRVQLVVGDGRM 203
Cdd:PRK08287  21 ALALSKL--ELHRAKHLIDVGAGTGSVSIEAALQF-PSLQVTAIERNPDALRLIKENRQR-----FGCGNIDIIPGEAPI 92

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 528961268 204 GYAAEApyDAIHVGAAAPVVpQALID----QLKPGGRLIL 239
Cdd:PRK08287  93 ELPGKA--DAIFIGGSGGNL-TAIIDwslaHLHPGGRLVL 129
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 127-239 4.97e-03

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 37.63  E-value: 4.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528961268  127 LELLFDQLNEGAKALDVGSGSGILtACFARMVGPSgKVIGIDhIKEL-VDDSINNVRKDDpmllSSGRVQLVVGDGRMgy 205
Cdd:pfam06325 152 LEALERLVKPGESVLDVGCGSGIL-AIAALKLGAK-KVVGVD-IDPVaVRAAKENAELNG----VEARLEVYLPGDLP-- 222

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 528961268  206 aaEAPYDAIHVGAAAPVVpQALIDQ----LKPGGRLIL 239
Cdd:pfam06325 223 --KEKADVVVANILADPL-IELAPDiyalVKPGGYLIL 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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