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Conserved domains on  [gi|544439030|ref|XP_005557732|]
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solute carrier family 12 member 2 isoform X2 [Macaca fascicularis]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
214-1194 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1625.56  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   214 NTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKE-----PFEDGFANGEESTP---TRDAVVTYTAESKGVVKFGW 285
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVvsllgPLADYTNNGQGMKEheeAEDAEGTKEKPPAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   286 IKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGA 365
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   366 IGLIFAFANAVAVAMYVVGFAETVVELLKEHSI-LMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAI 444
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLDLLRENGSkIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSI 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   445 GDFVIGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEET-FFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLA 523
Cdd:TIGR00930  241 LNIFVGTIIPAFDKPAKGFFGLGNEIFSENFIPGIPGPEGgFFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   524 ILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTeltNCTSAACklnfdFSSCESSPCSYGLMNNFQVMSMVSGFTPLISA 603
Cdd:TIGR00930  321 ILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC-----FSECAHNTCSYGLMNNLQVMSLVSPFPPLITA 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   604 GIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLAS 683
Cdd:TIGR00930  393 GIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLAS 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   684 YALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQAL 763
Cdd:TIGR00930  473 YALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQAL 552
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   764 TYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRW 843
Cdd:TIGR00930  553 SYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTW 632
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   844 LIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEG 923
Cdd:TIGR00930  633 LEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEG 712
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   924 LDISHLQGQEELlssqekspgtkdvvvSVEYSKKSDLDTSKPLSEKPVTHkeskgpivplnvadqklLEASTQFQKKQGK 1003
Cdd:TIGR00930  713 LPISVLQVQEEL---------------ENDCSEDSIELNDGKISTQPDMH-----------------LEASTQFQKKQGK 760
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1004 NTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKEN 1082
Cdd:TIGR00930  761 GTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAqKDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTES 840
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1083 IIAFEEMIEPYRLHEDDKEQDIAD-KMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVS 1161
Cdd:TIGR00930  841 MEAFEEMIRPFRLHKTEKDREAKDpKMTWTKPWKITDAELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIP 920
                          970       980       990
                   ....*....|....*....|....*....|...
gi 544439030  1162 SALYMAWLEALSKDLPPILLVRGNHQSVLTFYS 1194
Cdd:TIGR00930  921 DELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
214-1194 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1625.56  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   214 NTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKE-----PFEDGFANGEESTP---TRDAVVTYTAESKGVVKFGW 285
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVvsllgPLADYTNNGQGMKEheeAEDAEGTKEKPPAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   286 IKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGA 365
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   366 IGLIFAFANAVAVAMYVVGFAETVVELLKEHSI-LMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAI 444
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLDLLRENGSkIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSI 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   445 GDFVIGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEET-FFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLA 523
Cdd:TIGR00930  241 LNIFVGTIIPAFDKPAKGFFGLGNEIFSENFIPGIPGPEGgFFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   524 ILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTeltNCTSAACklnfdFSSCESSPCSYGLMNNFQVMSMVSGFTPLISA 603
Cdd:TIGR00930  321 ILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC-----FSECAHNTCSYGLMNNLQVMSLVSPFPPLITA 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   604 GIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLAS 683
Cdd:TIGR00930  393 GIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLAS 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   684 YALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQAL 763
Cdd:TIGR00930  473 YALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQAL 552
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   764 TYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRW 843
Cdd:TIGR00930  553 SYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTW 632
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   844 LIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEG 923
Cdd:TIGR00930  633 LEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEG 712
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   924 LDISHLQGQEELlssqekspgtkdvvvSVEYSKKSDLDTSKPLSEKPVTHkeskgpivplnvadqklLEASTQFQKKQGK 1003
Cdd:TIGR00930  713 LPISVLQVQEEL---------------ENDCSEDSIELNDGKISTQPDMH-----------------LEASTQFQKKQGK 760
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1004 NTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKEN 1082
Cdd:TIGR00930  761 GTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAqKDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTES 840
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1083 IIAFEEMIEPYRLHEDDKEQDIAD-KMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVS 1161
Cdd:TIGR00930  841 MEAFEEMIRPFRLHKTEKDREAKDpKMTWTKPWKITDAELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIP 920
                          970       980       990
                   ....*....|....*....|....*....|...
gi 544439030  1162 SALYMAWLEALSKDLPPILLVRGNHQSVLTFYS 1194
Cdd:TIGR00930  921 DELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
799-1194 0e+00

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 655.07  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   799 RPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSidQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMK 878
Cdd:pfam03522    1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSEL--QKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLK 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   879 PNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELL-----------------SSQEK 941
Cdd:pfam03522   79 PNILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDQDTEelglgdetnssyaeqssEEQST 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   942 SPGTKDVVVSVEYSKKSDLDTSKP-----------LSEKPVTHKESKGPIVPLNvADQKLLEASTQFQKKQGKNTIDVWW 1010
Cdd:pfam03522  159 SNSKQDDDKSKLSKKDSNLSLSPDkstknpsgkdsSKSDKLKKKSPSIILRTAS-NEKEILNNITQFQKKQKKGTIDVWW 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1011 LFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFEEM 1089
Cdd:pfam03522  238 LYDDGGLTLLLPYILSTRSKWSDCKLRVFALGnRKDELEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETKKFFDEL 317
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1090 IEPYRLHEDDKEQDIAdkmkedepWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWL 1169
Cdd:pfam03522  318 IEPFRLHEDDKEEESA--------EKITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWL 389
                          410       420
                   ....*....|....*....|....*
gi 544439030  1170 EALSKDLPPILLVRGNHQSVLTFYS 1194
Cdd:pfam03522  390 ETLTKDLPPFLLVRGNQTSVLTFYS 414
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
296-751 3.23e-43

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 163.91  E-value: 3.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  296 NIWGVMLFIRLSWIVGQAGiGLSVLVIMMATVVTTITGLSTSAIATNgFVRGGGAYYLISRSLGPEFGGAIGLIFAFANA 375
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA-FPRAGGAYTYARRALGPLLGFLAGWALLLSYV 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  376 VAVAMYVVGFAETVVELLKEHSILmideindirIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGtfipl 455
Cdd:COG0531   103 LAVAAVAVAFGGYLSSLFPAGGSV---------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLLLFIVV----- 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  456 eskkpkGFFGYKSEIFNeNFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIA 535
Cdd:COG0531   169 ------GLFAFDPANFT-PFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVS 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  536 VSVGSCVVRDATGNVNDTIvteltnctsaacklnfdfsscesspcsyglmnnFQVMSMVSG--FTPLISAGIFSATLSSA 613
Cdd:COG0531   242 LALTGVVPYDELAASGAPL---------------------------------ADAAEAVFGpwGAILIALGALLSLLGAL 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  614 LASLVSAPKIFQALCKDNIYPAFqmFAKGYGKNNEPLRGYILTFLIALGFILI--AELNVIAPIISNFFLASYALINFSV 691
Cdd:COG0531   289 NASILGASRLLYAMARDGLLPKV--FAKVHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAV 366
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544439030  692 FhASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYV-IVLGLYIYVTYKK 751
Cdd:COG0531   367 I-VLRRRRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGALLIGLVlLAIGLLLYLLYRR 426
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
214-1194 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1625.56  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   214 NTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKE-----PFEDGFANGEESTP---TRDAVVTYTAESKGVVKFGW 285
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVvsllgPLADYTNNGQGMKEheeAEDAEGTKEKPPAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   286 IKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGA 365
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   366 IGLIFAFANAVAVAMYVVGFAETVVELLKEHSI-LMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAI 444
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLDLLRENGSkIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSI 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   445 GDFVIGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEET-FFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLA 523
Cdd:TIGR00930  241 LNIFVGTIIPAFDKPAKGFFGLGNEIFSENFIPGIPGPEGgFFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   524 ILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTeltNCTSAACklnfdFSSCESSPCSYGLMNNFQVMSMVSGFTPLISA 603
Cdd:TIGR00930  321 ILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC-----FSECAHNTCSYGLMNNLQVMSLVSPFPPLITA 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   604 GIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLAS 683
Cdd:TIGR00930  393 GIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLAS 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   684 YALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQAL 763
Cdd:TIGR00930  473 YALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQAL 552
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   764 TYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRW 843
Cdd:TIGR00930  553 SYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTW 632
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   844 LIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEG 923
Cdd:TIGR00930  633 LEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEG 712
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   924 LDISHLQGQEELlssqekspgtkdvvvSVEYSKKSDLDTSKPLSEKPVTHkeskgpivplnvadqklLEASTQFQKKQGK 1003
Cdd:TIGR00930  713 LPISVLQVQEEL---------------ENDCSEDSIELNDGKISTQPDMH-----------------LEASTQFQKKQGK 760
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1004 NTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKEN 1082
Cdd:TIGR00930  761 GTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAqKDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTES 840
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1083 IIAFEEMIEPYRLHEDDKEQDIAD-KMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVS 1161
Cdd:TIGR00930  841 MEAFEEMIRPFRLHKTEKDREAKDpKMTWTKPWKITDAELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIP 920
                          970       980       990
                   ....*....|....*....|....*....|...
gi 544439030  1162 SALYMAWLEALSKDLPPILLVRGNHQSVLTFYS 1194
Cdd:TIGR00930  921 DELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
799-1194 0e+00

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 655.07  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   799 RPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSidQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMK 878
Cdd:pfam03522    1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSEL--QKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLK 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   879 PNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELL-----------------SSQEK 941
Cdd:pfam03522   79 PNILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDQDTEelglgdetnssyaeqssEEQST 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   942 SPGTKDVVVSVEYSKKSDLDTSKP-----------LSEKPVTHKESKGPIVPLNvADQKLLEASTQFQKKQGKNTIDVWW 1010
Cdd:pfam03522  159 SNSKQDDDKSKLSKKDSNLSLSPDkstknpsgkdsSKSDKLKKKSPSIILRTAS-NEKEILNNITQFQKKQKKGTIDVWW 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1011 LFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFEEM 1089
Cdd:pfam03522  238 LYDDGGLTLLLPYILSTRSKWSDCKLRVFALGnRKDELEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETKKFFDEL 317
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  1090 IEPYRLHEDDKEQDIAdkmkedepWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWL 1169
Cdd:pfam03522  318 IEPFRLHEDDKEEESA--------EKITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWL 389
                          410       420
                   ....*....|....*....|....*
gi 544439030  1170 EALSKDLPPILLVRGNHQSVLTFYS 1194
Cdd:pfam03522  390 ETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease pfam00324
Amino acid permease;
288-790 1.62e-133

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 415.18  E-value: 1.62e-133
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   288 GVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVrGGGAYYLISRSLGPEFGGAIG 367
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   368 LIFAFanavavaMYVVGFA-ETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGD 446
Cdd:pfam00324   80 WNYWL-------SWITVLAlELTAASILIQFWELVPDIPYLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIG 152
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   447 FVIGTFIPLESKKPK---GFFGYKSEIFNENFGPDFreEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLA 523
Cdd:pfam00324  153 FIIVGIILLSGGNPNdgaIFRYLGDNGGKNNFPPGF--GKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQV 230
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   524 ILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTeltnctsaacklnfdfsscesspcsYGLMNNFQVMSMVSGFTPLISA 603
Cdd:pfam00324  231 IWRITIFYILSLLAIGLLVPWNDPGLLNDSASA-------------------------ASPFVIFFKFLGISGLAPLINA 285
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   604 GIFSATLSSALASLVSAPKIFQALCKDNIYPafqMFAKGYGKNNEPLRGYILTFLIALGFILIAELNviAPIISNFFLAS 683
Cdd:pfam00324  286 VILTAALSAANSSLYSGSRMLYSLARDGLAP---KFLKKVDKRGVPLRAILVSMVISLLALLLASLN--PAIVFNFLLAI 360
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   684 YALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQAL 763
Cdd:pfam00324  361 SGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAA 440
                          490       500
                   ....*....|....*....|....*..
gi 544439030   764 TYLNALQHSIRLSGVEDHVKNFRPQCL 790
Cdd:pfam00324  441 AYLIVLLFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
296-751 3.23e-43

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 163.91  E-value: 3.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  296 NIWGVMLFIRLSWIVGQAGiGLSVLVIMMATVVTTITGLSTSAIATNgFVRGGGAYYLISRSLGPEFGGAIGLIFAFANA 375
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA-FPRAGGAYTYARRALGPLLGFLAGWALLLSYV 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  376 VAVAMYVVGFAETVVELLKEHSILmideindirIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGtfipl 455
Cdd:COG0531   103 LAVAAVAVAFGGYLSSLFPAGGSV---------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLLLFIVV----- 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  456 eskkpkGFFGYKSEIFNeNFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIA 535
Cdd:COG0531   169 ------GLFAFDPANFT-PFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVS 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  536 VSVGSCVVRDATGNVNDTIvteltnctsaacklnfdfsscesspcsyglmnnFQVMSMVSG--FTPLISAGIFSATLSSA 613
Cdd:COG0531   242 LALTGVVPYDELAASGAPL---------------------------------ADAAEAVFGpwGAILIALGALLSLLGAL 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030  614 LASLVSAPKIFQALCKDNIYPAFqmFAKGYGKNNEPLRGYILTFLIALGFILI--AELNVIAPIISNFFLASYALINFSV 691
Cdd:COG0531   289 NASILGASRLLYAMARDGLLPKV--FAKVHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAV 366
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544439030  692 FhASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYV-IVLGLYIYVTYKK 751
Cdd:COG0531   367 I-VLRRRRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGALLIGLVlLAIGLLLYLLYRR 426
AA_permease_N pfam08403
Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid ...
200-262 1.09e-32

Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid permease domain (pfam00324) in metazoan Na-K-Cl cotransporters.


Pssm-ID: 429977  Cd Length: 70  Bit Score: 121.01  E-value: 1.09e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   200 DTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEK-------EPFEDGFANGEE 262
Cdd:pfam08403    1 DTHGSTYYLQTFGHNTLDAVPRIDFYRNTGSVSGVKKSRPSLAELHSQLKKnsalavaEGSVDGVENGDG 70
AA_permease_2 pfam13520
Amino acid permease;
313-733 2.33e-14

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 76.97  E-value: 2.33e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   313 AGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVEL 392
Cdd:pfam13520   27 SGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNWFAYVLGLASSASVAASYLLSA 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   393 LKEhsiLMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIgtFIPLESKKPKGFFGYKSEifN 472
Cdd:pfam13520  107 LGP---DLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLPLILII--ILGLVTADGGGFNLLSGE--W 179
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   473 ENFGPDFreEETFFSVFAIFFPAATGILAGANISGDlaDPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVND 552
Cdd:pfam13520  180 HTFFPDG--WPGVFAGFLGVLWSFTGFESAANVSEE--VKKRNVPKAIFIGVIIVGVLYILVNIAFFGVVPDDEIALSSG 255
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   553 TIvteltnctsaacklnfdfsscesspcsyGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNI 632
Cdd:pfam13520  256 LG----------------------------QVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGV 307
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544439030   633 YPAFQMFAKgYGKNNEPLRGYILTFLIALGFILIAelnVIAPIISNFFLASYALINFSVFHASLA-------KSPGWRpa 705
Cdd:pfam13520  308 LPFSRFFAK-VNKFGSPIRAIILTAILSLILLLLF---LLSPAAYNALLSLSAYGYLLSYLLPIIgllilrkKRPDLG-- 381
                          410       420
                   ....*....|....*....|....*...
gi 544439030   706 fKYYNMWISLLGAILCCIVMFVINWWAA 733
Cdd:pfam13520  382 -RIPGRWPVAIFGILFSLFLIVALFFPP 408
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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