NCBI Conserved Domain Search

Conserved domains on [gi|564332128|ref|XP_006230793|]

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NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1 [Rattus norvegicus]

Protein Classification

NuoI/complex I 23 kDa subunit family protein( domain architecture ID 11481829)

NuoI/complex I 23 kDa subunit family protein such as bacterial NADH-quinone oxidoreductase subunit I (NuoI), which is part of the connecting domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

EC: 7.1.1.-

Gene Ontology: GO:0016651|GO:0051539|GO:0016020

PubMed: 23417064|33957129|24059520

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

PRK05888

NADH-quinone oxidoreductase subunit NuoI;

57-212

5.37e-95

NADH-quinone oxidoreductase subunit NuoI;

Pssm-ID: 235637 [Multi-domain] Cd Length: 164 Bit Score: 274.07 E-value: 5.37e-95

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  57 AARILMWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRA 136
Cdd:PRK05888   4 YLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAERE 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128 137 DGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 212
Cdd:PRK05888  84 DGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159

Name

Accession

Description

Interval

E-value

PRK05888

NADH-quinone oxidoreductase subunit NuoI;

57-212

5.37e-95

NADH-quinone oxidoreductase subunit NuoI;

Pssm-ID: 235637 [Multi-domain] Cd Length: 164 Bit Score: 274.07 E-value: 5.37e-95

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  57 AARILMWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRA 136
Cdd:PRK05888   4 YLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAERE 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128 137 DGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 212
Cdd:PRK05888  84 DGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159

NuoI

TIGR01971

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...

69-190

1.44e-64

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]

Pssm-ID: 273902 [Multi-domain] Cd Length: 122 Bit Score: 195.33 E-value: 1.44e-64

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128   69 GLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDID 148
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEIN 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 564332128  149 MTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKL 190
Cdd:TIGR01971  81 FGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122

NuoI

COG1143

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...

110-182

3.56e-23

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase

Pssm-ID: 440758 [Multi-domain] Cd Length: 66 Bit Score: 88.26 E-value: 3.56e-23

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPnFEFSTETHEE 182
Cdd:COG1143    1 EDKCIGCGLCVRVCPVDAITIEDG------EPGKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

110-168

1.64e-17

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 75.13 E-value: 1.64e-17

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADgsrrttrydIDMTKCIYCGFCQEACPVDAIV 168
Cdd:cd10549   77 EEKCIGCGLCVKVCPVDAITLEDELEIV---------IDKEKCIGCGICAEVCPVNAIK 126

Fer4_7

pfam12838

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...

113-166

2.20e-13

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.

Pssm-ID: 463724 [Multi-domain] Cd Length: 51 Bit Score: 62.16 E-value: 2.20e-13

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564332128  113 CIACKLCEAICPAQAITIEAEPRADGsrrTTRYDIDMTKCIYCGFCQEACPVDA 166
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKG---TKTVVIDPERCVGCGACVAVCPTGA 51

ferrodoxin_EFR1

NF038196

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...

77-167

1.07e-06

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).

Pssm-ID: 468407 [Multi-domain] Cd Length: 243 Bit Score: 47.55 E-value: 1.07e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  77 LFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAE-PRADGsrrttrydidmtKCIYC 155
Cdd:NF038196 151 GPEKKKGFIPRLLSKLVNPLFYKFKVKDKKFHVTDKCIGCGICAKVCPVNNIEMEDGkPVWGH------------NCTHC 218

                         90
                 ....*....|..
gi 564332128 156 GFCQEACPVDAI 167
Cdd:NF038196 219 LACIHRCPKEAI 230

Name

Accession

Description

Interval

E-value

PRK05888

NADH-quinone oxidoreductase subunit NuoI;

57-212

5.37e-95

NADH-quinone oxidoreductase subunit NuoI;

Pssm-ID: 235637 [Multi-domain] Cd Length: 164 Bit Score: 274.07 E-value: 5.37e-95

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  57 AARILMWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRA 136
Cdd:PRK05888   4 YLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAERE 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128 137 DGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 212
Cdd:PRK05888  84 DGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159

NuoI

TIGR01971

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...

69-190

1.44e-64

Pssm-ID: 273902 [Multi-domain] Cd Length: 122 Bit Score: 195.33 E-value: 1.44e-64

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128   69 GLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDID 148
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEIN 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 564332128  149 MTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKL 190
Cdd:TIGR01971  81 FGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122

NuoI

COG1143

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...

110-182

3.56e-23

Pssm-ID: 440758 [Multi-domain] Cd Length: 66 Bit Score: 88.26 E-value: 3.56e-23

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPnFEFSTETHEE 182
Cdd:COG1143    1 EDKCIGCGLCVRVCPVDAITIEDG------EPGKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66

ndhI

CHL00014

NADH dehydrogenase subunit I

68-187

4.73e-19

NADH dehydrogenase subunit I

Pssm-ID: 214334 [Multi-domain] Cd Length: 167 Bit Score: 80.19 E-value: 4.73e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  68 RGLGMTLSYLFREPATINYPFEKGPLSPRFRGehalrRYPSGEERCIACKLCEAICPAQAITIEAEPRAD-GSRRTTRYD 146
Cdd:CHL00014  21 QGFMITLSHANRLPVTIQYPYEKLITSERFRG-----RIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDiRKKRLLNYS 95

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 564332128 147 IDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNK 187
Cdd:CHL00014  96 IDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQ 136

PRK12387

formate hydrogenlyase complex iron-sulfur subunit; Provisional

81-188

1.36e-17

formate hydrogenlyase complex iron-sulfur subunit; Provisional

Pssm-ID: 183492 [Multi-domain] Cd Length: 180 Bit Score: 76.99 E-value: 1.36e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  81 PATINYPFEKGPLSPRFRG--EHALrrypsgeERCIACKLCEAICPAQAITIEAepraDGSRRTTRYDIDMTKCIYCGFC 158
Cdd:PRK12387  13 TATSSYPLEPIAVDKNFRGkpEYNP-------QQCIGCAACVNACPSNALTVET----DLATGELAWEFNLGRCIFCGRC 81

                         90       100       110
                 ....*....|....*....|....*....|
gi 564332128 159 QEACPVDAIVEGPNFEFSTETHEELLYNKE 188
Cdd:PRK12387  82 EEVCPTAAIKLSQEFELAVWKKEDLLQQSE 111

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

110-168

1.64e-17

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 75.13 E-value: 1.64e-17

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADgsrrttrydIDMTKCIYCGFCQEACPVDAIV 168
Cdd:cd10549   77 EEKCIGCGLCVKVCPVDAITLEDELEIV---------IDKEKCIGCGICAEVCPVNAIK 126

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

110-189

1.08e-15

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 70.50 E-value: 1.08e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 110 EERCIACKLCEAICPAQAITIEaepraDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEK 189
Cdd:cd10549    5 PEKCIGCGICVKACPTDAIELG-----PNGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAEIDEEK 79

PRK08222

hydrogenase 4 subunit H; Validated

82-187

1.67e-15

hydrogenase 4 subunit H; Validated

Pssm-ID: 181301 [Multi-domain] Cd Length: 181 Bit Score: 71.32 E-value: 1.67e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  82 ATINYPFEKGPLSPRFRGEHALrrypsGEERCIACKLCEAICPAQAITIEAepraDGSRRTTRYDIDMTKCIYCGFCQEA 161
Cdd:PRK08222  14 ATVKYPFAPLEVSPGFRGKPDL-----MPSQCIACGACTCACPANALTIQT----DDQQNSRTWQLYLGRCIYCGRCEEV 84

                         90       100
                 ....*....|....*....|....*.
gi 564332128 162 CPVDAIVEGPNFEFsTETHEELLYNK 187
Cdd:PRK08222  85 CPTRAIQLTNNFEL-TVTNKADLYTR 109

DsrA

COG2221

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...

110-175

1.86e-15

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];

Pssm-ID: 441823 [Multi-domain] Cd Length: 69 Bit Score: 68.15 E-value: 1.86e-15

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsrrttRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEF 175
Cdd:COG2221   14 EEKCIGCGLCVAVCPTGAISLDDG----------KLVIDEEKCIGCGACIRVCPTGAIKGEKPKKF 69

COG2768

Uncharacterized Fe-S cluster protein [Function unknown];

101-174

1.87e-15

Uncharacterized Fe-S cluster protein [Function unknown];

Pssm-ID: 442050 [Multi-domain] Cd Length: 74 Bit Score: 68.22 E-value: 1.87e-15

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564332128 101 HALRRYPSGEERCIACKLCEAICPAQAITIEAEPradgsrrttrYDIDMTKCIYCGFCQEACPVDAIVEGPNFE 174
Cdd:COG2768    1 HSLGKPYVDEEKCIGCGACVKVCPVGAISIEDGK----------AVIDPEKCIGCGACIEVCPVGAIKIEWEED 64

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

110-167

7.86e-14

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 65.50 E-value: 7.86e-14

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAITIEaEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd10549   39 EDKCVFCGACVEVCPTGAIELT-PEGKEYVPKEKEAEIDEEKCIGCGLCVKVCPVDAI 95

IorA

COG4231

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...

110-168

1.11e-13

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];

Pssm-ID: 443375 [Multi-domain] Cd Length: 76 Bit Score: 63.52 E-value: 1.11e-13

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydIDMTKCIYCGFCQEACPVDAIV 168
Cdd:COG4231   21 EDKCTGCGACVKVCPADAIEEGDGKAV----------IDPDLCIGCGSCVQVCPVDAIK 69

PRK13984

putative oxidoreductase; Provisional

76-162

1.24e-13

putative oxidoreductase; Provisional

Pssm-ID: 172486 [Multi-domain] Cd Length: 604 Bit Score: 69.03 E-value: 1.24e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  76 YLFREPATINYPFEKGPLSPRFRGEHAlrrypSGEERCIACKLCEAICPAQAIT---IEAEPRADGSrRTTRYDIDMTKC 152
Cdd:PRK13984  15 FLFRKPVTIKVPNVKREAAERYRGFHI-----NDWEKCIGCGTCSKICPTDAITmveVPDLPQEYGK-KPQRPVIDYGRC 88

                         90
                 ....*....|
gi 564332128 153 IYCGFCQEAC 162
Cdd:PRK13984  89 SFCALCVDIC 98

Fer4_7

pfam12838

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...

113-166

2.20e-13

Pssm-ID: 463724 [Multi-domain] Cd Length: 51 Bit Score: 62.16 E-value: 2.20e-13

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564332128  113 CIACKLCEAICPAQAITIEAEPRADGsrrTTRYDIDMTKCIYCGFCQEACPVDA 166
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKG---TKTVVIDPERCVGCGACVAVCPTGA 51

PorD

COG1144

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...

110-168

9.89e-13

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation

Pssm-ID: 440759 [Multi-domain] Cd Length: 84 Bit Score: 61.22 E-value: 9.89e-13

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYDIDMTKCIYCGFCQEACPVDAIV 168
Cdd:COG1144   29 EDKCIGCGLCWIVCPDGAIRVDDG---------KYYGIDYDYCKGCGICAEVCPVKAIE 78

COG1149

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...

110-171

1.56e-12

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];

Pssm-ID: 440763 [Multi-domain] Cd Length: 68 Bit Score: 60.51 E-value: 1.56e-12

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYDIDMTKCIYCGFCQEACPVDAIVEGP 171
Cdd:COG1149   10 EEKCIGCGLCVEVCPEGAIKLDDG---------GAPVVDPDLCTGCGACVGVCPTGAITLEE 62

NapF

COG1145

Ferredoxin [Energy production and conversion];

110-167

1.59e-12

Ferredoxin [Energy production and conversion];

Pssm-ID: 440760 [Multi-domain] Cd Length: 238 Bit Score: 64.36 E-value: 1.59e-12

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsrrTTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG1145  181 AEKCIGCGLCVKVCPTGAIRLKDG--------KPQIVVDPDKCIGCGACVKVCPVGAI 230

PreA

COG1146

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...

110-167

5.58e-12

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];

Pssm-ID: 440761 [Multi-domain] Cd Length: 67 Bit Score: 58.95 E-value: 5.58e-12

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgSRRTTRYDIDmtKCIYCGFCQEACPVDAI 167
Cdd:COG1146    7 TDKCIGCGACVEVCPVDVLELDEE-----GKKALVINPE--ECIGCGACELVCPVGAI 57

PRK08348

NADH-plastoquinone oxidoreductase subunit; Provisional

70-178

1.10e-11

NADH-plastoquinone oxidoreductase subunit; Provisional

Pssm-ID: 181399 [Multi-domain] Cd Length: 120 Bit Score: 59.46 E-value: 1.10e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  70 LGMTLSYLFREPATINYP-FEKGPLSPRFRGEHALRRypsgeERCIACKLCEAICPAQAITIEAEPRadgsrrttRYDID 148
Cdd:PRK08348   5 LPTVLRNLFKKPATNLFPaTEPVPVPEDFRGKILYDV-----DKCVGCRMCVTVCPAGVFVYLPEIR--------KVALW 71

                         90       100       110
                 ....*....|....*....|....*....|
gi 564332128 149 MTKCIYCGFCQEACPVDAIVEGPNFEFSTE 178
Cdd:PRK08348  72 TGRCVFCGQCVDVCPTGALQMSDDFLLASY 101

Nar1

COG4624

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

110-169

6.20e-10

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

Pssm-ID: 443663 [Multi-domain] Cd Length: 450 Bit Score: 57.73 E-value: 6.20e-10

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 110 EERCIACKLCEAICPAQAITIEaepraDGSRRttrydIDMTKCIYCGFCQEACPVDAIVE 169
Cdd:COG4624   90 KEKCKNCYPCVRACPVKAIKVD-----DGKAE-----IDEEKCISCGQCVAVCPFGAITE 139

PRK07118

Fe-S cluster domain-containing protein;

113-169

6.58e-10

Fe-S cluster domain-containing protein;

Pssm-ID: 235941 [Multi-domain] Cd Length: 280 Bit Score: 57.25 E-value: 6.58e-10

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564332128 113 CIACKLCEAICPAQAITIEaepradgsrrTTRYDIDMTKCIYCGFCQEACPVDAIVE 169
Cdd:PRK07118 215 CIGCGKCVKACPAGAITME----------NNLAVIDQEKCTSCGKCVEKCPTKAIRI 261

Fer4_9

pfam13187

4Fe-4S dicluster domain;

112-167

9.06e-10

4Fe-4S dicluster domain;

Pssm-ID: 463801 [Multi-domain] Cd Length: 50 Bit Score: 52.56 E-value: 9.06e-10

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128  112 RCIACKLCEAICPAQAITIeaepraDGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:pfam13187   1 KCTGCGACVAACPAGAIVP------DLVGQTIRGDIAGLACIGCGACVDACPRGAI 50

HdrA

COG1148

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];

110-167

1.11e-09

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];

Pssm-ID: 440762 [Multi-domain] Cd Length: 563 Bit Score: 57.18 E-value: 1.11e-09

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRAdgsrrttryDIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG1148  495 PEKCTGCGRCVEVCPYGAISIDEKGVA---------EVNPALCKGCGTCAAACPSGAI 543

PRK06273

ferredoxin; Provisional

110-164

1.35e-08

ferredoxin; Provisional

Pssm-ID: 235764 [Multi-domain] Cd Length: 165 Bit Score: 52.02 E-value: 1.35e-08

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAIT-IEAEPR--ADGSRRTTRYDIDMTKCIYCGFCQEACPV 164
Cdd:PRK06273  48 EELCIGCGGCANVCPTKAIEmIPVEPVkiTEGYVKTKIPKIDYEKCVYCLYCHDFCPV 105

FeFe_hydrog_B1

TIGR04105

[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.

111-169

2.89e-08

[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.

Pssm-ID: 274983 [Multi-domain] Cd Length: 462 Bit Score: 52.98 E-value: 2.89e-08

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128  111 ERCIACKLCEAICPAQAIT------IEAEP-RADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVE 169
Cdd:TIGR04105 142 EKCIECGKCKKACPYNAIVeierpcEKACPvGAISSDEDGRAVIDYDKCISCGACMVACPFGAISD 207

PRK14028

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional

112-167

1.01e-07

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional

Pssm-ID: 172522 [Multi-domain] Cd Length: 312 Bit Score: 51.15 E-value: 1.01e-07

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 112 RCIACKLCEAICPAQAItIEAEPRADGSR----RTTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:PRK14028 248 KCIMCRKCWLYCPDDAI-IEAWREAEGPRgrkfRMKMIDFDYQYCKGCGVCAEVCPTGAI 306

HycB_like

cd10554

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...

110-167

1.34e-07

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.

Pssm-ID: 319876 [Multi-domain] Cd Length: 149 Bit Score: 49.18 E-value: 1.34e-07

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIdMTKCIYCGF------CQEACPVDAI 167
Cdd:cd10554   84 EERCIGCKLCVLACPFGAIEMAPTTVPGVDWERGPRAV-AVKCDLCAGreggpaCVEACPTKAL 146

PsrB

cd10551

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...

111-176

1.52e-07

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.

Pssm-ID: 319873 [Multi-domain] Cd Length: 185 Bit Score: 49.45 E-value: 1.52e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 111 ERCIACKLCEAICPAQAITI-EAEPRADGSRRTTRYDIdMTKCIYC------G---FCQEACPVDAIVEG----PNFEFS 176
Cdd:cd10551   83 DKCIGCRYCMAACPYGARYFnPEEPHEFGEVPVRPKGV-VEKCTFCyhrldeGllpACVEACPTGARIFGdlddPNSEVS 161

PRK13795

hypothetical protein; Provisional

112-164

1.65e-07

hypothetical protein; Provisional

Pssm-ID: 237510 [Multi-domain] Cd Length: 636 Bit Score: 50.76 E-value: 1.65e-07

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 564332128 112 RCIACKLCEAICPAQAITIEAEPRadgsrrttRYDIDMTKCIYCGFCQEACPV 164
Cdd:PRK13795 582 ECVGCGVCVGACPTGAIRIEEGKR--------KISVDEEKCIHCGKCTEVCPV 626

DMSOR_beta-like

cd04410

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...

100-168

1.86e-07

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.

Pssm-ID: 319870 [Multi-domain] Cd Length: 136 Bit Score: 48.54 E-value: 1.86e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 100 EHALRRYPSG-----EERCIACKLCEAICPAQAITIEAEPRadgsrrttrydiDMTKCIYCGF---------CQEACPVD 165
Cdd:cd04410   64 TGAIYKDEDGivlidEDKCIGCGSCVEACPYGAIVFDPEPG------------KAVKCDLCGDrldeglepaCVKACPTG 131


                 ...
gi 564332128 166 AIV 168
Cdd:cd04410  132 ALT 134

NapF_like

cd10564

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...

114-167

1.96e-07

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.

Pssm-ID: 319886 [Multi-domain] Cd Length: 139 Bit Score: 48.39 E-value: 1.96e-07

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 564332128 114 IACKLCEAICPAQAITIEaePRADGSRRTTrydIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd10564   86 VECRSCQDACPTQAIRFR--PRLGGIALPE---LDADACTGCGACVSVCPVGAI 134

NapH

COG0348

Polyferredoxin NapH [Energy production and conversion];

110-167

2.22e-07

Polyferredoxin NapH [Energy production and conversion];

Pssm-ID: 440117 [Multi-domain] Cd Length: 263 Bit Score: 49.68 E-value: 2.22e-07

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAItieaePRaDGSrrttrydIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG0348  209 RGDCIDCGLCVKVCPMGID-----IR-KGE-------INQSECINCGRCIDACPKDAI 253

HycB

COG1142

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

110-168

2.97e-07

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

Pssm-ID: 440757 [Multi-domain] Cd Length: 138 Bit Score: 48.11 E-value: 2.97e-07

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADGSrrttrydidmTKCIYCGF------CQEACPVDAIV 168
Cdd:COG1142   80 EEKCIGCGLCVLACPFGAITMVGEKSRAVA----------VKCDLCGGreggpaCVEACPTGALR 134

HycB

COG1142

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

113-167

3.09e-07

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

Pssm-ID: 440757 [Multi-domain] Cd Length: 138 Bit Score: 47.73 E-value: 3.09e-07

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564332128 113 CIACKL--CEAICPAQAITieaepradgsRRTTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG1142   52 CRHCEDapCAEVCPVGAIT----------RDDGAVVVDEEKCIGCGLCVLACPFGAI 98

DMSOR_beta_like

cd10550

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

104-168

5.16e-07

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.

Pssm-ID: 319872 [Multi-domain] Cd Length: 130 Bit Score: 47.19 E-value: 5.16e-07

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 104 RRYPSGEERCIACKLCE-----AICPAQAITIEAEpradgsrrTTRYDIDMTKCIYCGFCQEACPVDAIV 168
Cdd:cd10550   37 RFEPEGLDVPVVCRQCEdapcvEACPVGAISRDEE--------TGAVVVDEDKCIGCGMCVEACPFGAIR 98

HybA

COG0437

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...

101-168

5.20e-07

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];

Pssm-ID: 440206 [Multi-domain] Cd Length: 184 Bit Score: 48.02 E-value: 5.20e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 101 HALRRYPSG-----EERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydidMTKCIYCGF---------CQEACPVDA 166
Cdd:COG0437   75 GATYKREDGivlvdYDKCIGCRYCVAACPYGAPRFNPETGV------------VEKCTFCADrldegllpaCVEACPTGA 142


                 ..
gi 564332128 167 IV 168
Cdd:COG0437  143 LV 144

DMSOR_beta_like

cd16373

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

110-168

5.41e-07

Pssm-ID: 319895 [Multi-domain] Cd Length: 154 Bit Score: 47.64 E-value: 5.41e-07

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIA------CKLCEAICPAQAITIEAEpraDGSRRTTrydIDMTKCIYCGFCQEACPVD---AIV 168
Cdd:cd16373   90 KDRCLAwqggtdCGVCVEACPTEAIAIVLE---DDVLRPV---VDEDKCVGCGLCEYVCPVEppkAIV 151

Nar1

COG4624

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

112-167

5.98e-07

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

Pssm-ID: 443663 [Multi-domain] Cd Length: 450 Bit Score: 48.87 E-value: 5.98e-07

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128 112 RCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG4624   53 RCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAI 108

PRK12771

putative glutamate synthase (NADPH) small subunit; Provisional

113-171

6.63e-07

putative glutamate synthase (NADPH) small subunit; Provisional

Pssm-ID: 237198 [Multi-domain] Cd Length: 564 Bit Score: 49.10 E-value: 6.63e-07

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 113 CIACKLCEAICPAQAITIEAEPRadgsrrttRYDIDMTKCIYCGFCQEACPVDAIVEGP 171
Cdd:PRK12771 512 CFECDNCYGACPQDAIIKLGPGR--------RYHFDYDKCTGCHICADVCPCGAIEMGP 562

Fer4_10

pfam13237

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...

110-163

8.66e-07

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.

Pssm-ID: 404174 [Multi-domain] Cd Length: 56 Bit Score: 44.55 E-value: 8.66e-07

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564332128  110 EERCIACKLCEAICPAQAITIEAEPRADGSRRTtryDIDMTKCIYCGFCQEACP 163
Cdd:pfam13237   6 PDKCIGCGRCTAACPAGLTRVGAIVERLEGEAV---RIGVWKCIGCGACVEACP 56

ferrodoxin_EFR1

NF038196

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...

77-167

1.07e-06

Pssm-ID: 468407 [Multi-domain] Cd Length: 243 Bit Score: 47.55 E-value: 1.07e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  77 LFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAE-PRADGsrrttrydidmtKCIYC 155
Cdd:NF038196 151 GPEKKKGFIPRLLSKLVNPLFYKFKVKDKKFHVTDKCIGCGICAKVCPVNNIEMEDGkPVWGH------------NCTHC 218

                         90
                 ....*....|..
gi 564332128 156 GFCQEACPVDAI 167
Cdd:NF038196 219 LACIHRCPKEAI 230

Fer4_16

pfam13484

4Fe-4S double cluster binding domain;

113-163

1.30e-06

4Fe-4S double cluster binding domain;

Pssm-ID: 463893 [Multi-domain] Cd Length: 65 Bit Score: 44.40 E-value: 1.30e-06

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564332128  113 CIACKLCEAICPAQAIT---IEAEPRADGSRRTTRYD---------IDMTKCIYCGFCQEACP 163
Cdd:pfam13484   1 CGSCGKCIDACPTGAIVgpeGVLDARRCISYLTIEKKglipdelrcLLGNRCYGCDICQDVCP 63

Fer4

pfam00037

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...

145-167

3.62e-06

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.

Pssm-ID: 459642 [Multi-domain] Cd Length: 24 Bit Score: 42.24 E-value: 3.62e-06

                          10        20
                  ....*....|....*....|...
gi 564332128  145 YDIDMTKCIYCGFCQEACPVDAI 167
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGAI 23

HybA

COG0437

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...

119-167

3.83e-06

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];

Pssm-ID: 440206 [Multi-domain] Cd Length: 184 Bit Score: 45.71 E-value: 3.83e-06

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 564332128 119 CEAICPAQAITIeaepRADGSRRttrydIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG0437   68 CVKVCPTGATYK----REDGIVL-----VDYDKCIGCRYCVAACPYGAP 107

DMSOR_beta_like

cd16370

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

113-167

4.44e-06

Pssm-ID: 319892 [Multi-domain] Cd Length: 131 Bit Score: 44.57 E-value: 4.44e-06

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564332128 113 CIACKL--CEAICPAQAItieaEPRADGSRRTTRydidmTKCIYCGFCQEACPVDAI 167
Cdd:cd16370   53 CRACEDppCAEACPTGAL----EPRKGGGVVLDK-----EKCIGCGNCVKACIVGAI 100

DMSOR_beta_like

cd16373

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

112-167

6.56e-06

Pssm-ID: 319895 [Multi-domain] Cd Length: 154 Bit Score: 44.55 E-value: 6.56e-06

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 112 RCIACKLCEAICPAQAITIeaEPRADGSR--RTTRYDIDMTKCIYCG-FCQEACPVDAI 167
Cdd:cd16373   15 LCIRCGLCVEACPTGVIQP--AGLEDGLEggRTPYLDPREGPCDLCCdACVEVCPTGAL 71

PRK12769

putative oxidoreductase Fe-S binding subunit; Reviewed

110-167

9.37e-06

putative oxidoreductase Fe-S binding subunit; Reviewed

Pssm-ID: 183733 [Multi-domain] Cd Length: 654 Bit Score: 45.51 E-value: 9.37e-06

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYdidmtKCIYCG------FCQEACPVDAI 167
Cdd:PRK12769  84 QQKCIGCKSCVVACPFGTMQIVLTPVAAGKVKATAH-----KCDLCAgrengpACVENCPADAL 142

vorD

PRK09623

3-methyl-2-oxobutanoate dehydrogenase subunit delta;

110-167

9.47e-06

3-methyl-2-oxobutanoate dehydrogenase subunit delta;

Pssm-ID: 170016 [Multi-domain] Cd Length: 105 Bit Score: 43.01 E-value: 9.47e-06

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAITIeaepRADGSrrttrYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:PRK09623  50 ESKCVKCYICWKFCPEPAIYI----KEDGY-----VAIDYDYCKGCGICANECPTKAI 98

NapF

COG1145

Ferredoxin [Energy production and conversion];

109-172

9.71e-06

Ferredoxin [Energy production and conversion];

Pssm-ID: 440760 [Multi-domain] Cd Length: 238 Bit Score: 45.10 E-value: 9.71e-06

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564332128 109 GEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPN 172
Cdd:COG1145  141 EAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDG 204

HycB

COG1142

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

111-173

1.08e-05

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

Pssm-ID: 440757 [Multi-domain] Cd Length: 138 Bit Score: 43.49 E-value: 1.08e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 111 ERCIACKLCEAICPAQAITIEAE---PRADGSRRTTRYDIDMtkCIYC--GFCQEACPVDAIVEGPNF 173
Cdd:COG1142   10 EKCIGCRTCEAACAVAHEGEEGEpflPRIRVVRKAGVSAPVQ--CRHCedAPCAEVCPVGAITRDDGA 75

DMSOR_beta_like

cd10550

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

110-167

1.29e-05

Pssm-ID: 319872 [Multi-domain] Cd Length: 130 Bit Score: 43.33 E-value: 1.29e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYdidMTKCIYCG---FCQEACPVDAI 167
Cdd:cd10550   79 EDKCIGCGMCVEACPFGAIRVDPE---------TGK---AIKCDLCGgdpACVKVCPTGAL 127

IorA

COG4231

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...

141-172

1.49e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];

Pssm-ID: 443375 [Multi-domain] Cd Length: 76 Bit Score: 41.57 E-value: 1.49e-05

                         10        20        30
                 ....*....|....*....|....*....|....
gi 564332128 141 RTT--RYDIDMTKCIYCGFCQEACPVDAIVEGPN 172
Cdd:COG4231   11 RTTamRYVIDEDKCTGCGACVKVCPADAIEEGDG 44

RnfB

COG2878

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...

110-167

2.94e-05

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase

Pssm-ID: 442125 [Multi-domain] Cd Length: 254 Bit Score: 43.44 E-value: 2.94e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 110 EERCIACKLCEAICPAQAITIEAE--PRadgsrrttrydIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG2878  136 EYGCIGCGDCIKACPFDAIVGAAKgmHT-----------VDEDKCTGCGLCVEACPVDCI 184

PRK09898

ferredoxin-like protein;

110-167

2.94e-05

ferredoxin-like protein;

Pssm-ID: 182135 [Multi-domain] Cd Length: 208 Bit Score: 43.29 E-value: 2.94e-05

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADgsrrttrydidmTKCIYCGFCQEACPVDAI 167
Cdd:PRK09898 153 HKRCIGCSACTTACPWMMATVNTESKKS------------SKCVLCGECANACPTGAL 198

PreA

COG1146

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...

147-182

2.98e-05

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];

Pssm-ID: 440761 [Multi-domain] Cd Length: 67 Bit Score: 40.85 E-value: 2.98e-05

                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 564332128 147 IDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEE 182
Cdd:COG1146    5 IDTDKCIGCGACVEVCPVDVLELDEEGKKALVINPE 40

DMSOR_beta-like

cd04410

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...

110-171

3.01e-05

Pssm-ID: 319870 [Multi-domain] Cd Length: 136 Bit Score: 42.38 E-value: 3.01e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPaQAITIEAEPRADGSRRTTRYDIDM----TKCIYCGF--CQEACPVDAIVEGP 171
Cdd:cd04410    5 LDRCIGCGTCEVACK-QEHGLRPGPDWSRIKVIEGGGLERaflpVSCMHCEDppCVKACPTGAIYKDE 71

PsrB

cd10551

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...

119-167

3.16e-05

Pssm-ID: 319873 [Multi-domain] Cd Length: 185 Bit Score: 42.90 E-value: 3.16e-05

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 564332128 119 CEAICPAQAITIeaepRADGsrrttRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd10551   61 CVKVCPTGATYK----REDG-----IVLVDYDKCIGCRYCMAACPYGAR 100

PreA

COG1146

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...

110-138

3.72e-05

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];

Pssm-ID: 440761 [Multi-domain] Cd Length: 67 Bit Score: 40.46 E-value: 3.72e-05

                         10        20
                 ....*....|....*....|....*....
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADG 138
Cdd:COG1146   39 PEECIGCGACELVCPVGAITVEDDEPEEQ 67

rnfB

TIGR01944

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...

110-168

3.73e-05

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]

Pssm-ID: 273887 [Multi-domain] Cd Length: 165 Bit Score: 42.48 E-value: 3.73e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128  110 EERCIACKLCEAICPAQAITieAEPRAdgsrrttRYDIDMTKCIYCGFCQEACPVDAIV 168
Cdd:TIGR01944 112 EDNCIGCTKCIQACPVDAIV--GAAKA-------MHTVIADECTGCDLCVEPCPTDCIE 161

DMSOR_beta_like

cd16371

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

119-168

4.20e-05

Pssm-ID: 319893 [Multi-domain] Cd Length: 140 Bit Score: 41.78 E-value: 4.20e-05

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 564332128 119 CEAICPAQAITIeaepRADGsrrTTRYDIDmtKCIYCGFCQEACPVDAIV 168
Cdd:cd16371   62 CVKVCPTGAITK----REDG---IVVVDQD--KCIGCGYCVWACPYGAPQ 102

NapF_like

cd10564

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...

104-167

5.10e-05

Pssm-ID: 319886 [Multi-domain] Cd Length: 139 Bit Score: 41.85 E-value: 5.10e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 104 RRYPSGEE-----RCIACKLCEAICPAQAITIeaepradGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd10564    1 RPPWAVDEalfldLCTRCGDCVEACPEGIIVR-------GDGGFPELDFSRGECTFCGACAEACPEGAL 62

DMSOR_beta_like

cd16370

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

102-167

6.32e-05

Pssm-ID: 319892 [Multi-domain] Cd Length: 131 Bit Score: 41.10 E-value: 6.32e-05

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564332128 102 ALRRYPSG-----EERCIACKLCEAICPAQAITIEAEpradgsrrtTRYDIdmtKCIYCGFCQEACPVDAI 167
Cdd:cd16370   69 ALEPRKGGgvvldKEKCIGCGNCVKACIVGAIFWDEE---------TNKPI---ICIHCGYCARYCPHDVL 127

COG1149

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...

147-168

7.27e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];

Pssm-ID: 440763 [Multi-domain] Cd Length: 68 Bit Score: 39.71 E-value: 7.27e-05

                         10        20
                 ....*....|....*....|..
gi 564332128 147 IDMTKCIYCGFCQEACPVDAIV 168
Cdd:COG1149    8 IDEEKCIGCGLCVEVCPEGAIK 29

porD

PRK09624

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed

110-168

8.55e-05

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed

Pssm-ID: 170017 [Multi-domain] Cd Length: 105 Bit Score: 40.40 E-value: 8.55e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEpradgsrrttRYDI-DMTKCIYCGFCQEACPVDAIV 168
Cdd:PRK09624  50 RDKCVRCYLCYIYCPEPAIYLDEE----------GYPVfDYDYCKGCGICANECPTKAIE 99

PorD

COG1144

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...

138-178

1.10e-04

Pssm-ID: 440759 [Multi-domain] Cd Length: 84 Bit Score: 39.65 E-value: 1.10e-04

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 564332128 138 GSRRTTRYDIDMTKCIYCGFCQEACPVDAI--VEGPNFEFSTE 178
Cdd:COG1144   18 GGWRVERPVVDEDKCIGCGLCWIVCPDGAIrvDDGKYYGIDYD 60

PRK08318

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;

110-169

1.14e-04

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;

Pssm-ID: 236237 [Multi-domain] Cd Length: 420 Bit Score: 42.24 E-value: 1.14e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564332128 110 EERCIACKLCEAIC---PAQAITIEAepraDGSRRttrYDIDMTKCIYCGFCQEACPVDAIVE 169
Cdd:PRK08318 341 QDKCIGCGRCYIACedtSHQAIEWDE----DGTRT---PEVIEEECVGCNLCAHVCPVEGCIT 396

DMSOR_beta_like

cd16374

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

112-167

1.45e-04

Pssm-ID: 319896 [Multi-domain] Cd Length: 139 Bit Score: 40.34 E-value: 1.45e-04

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 112 RCIACK--LCEAICPAQAITIEAepraDGSRRttrydIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd16374   42 RCRHCEdaPCMEVCPTGAIYRDE----DGAVL-----VDPDKCIGCGMCAMACPFGVP 90

PRK09898

ferredoxin-like protein;

111-163

1.86e-04

ferredoxin-like protein;

Pssm-ID: 182135 [Multi-domain] Cd Length: 208 Bit Score: 40.97 E-value: 1.86e-04

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 564332128 111 ERCIACK--LCEAICPAQAITIEAEPRAdgsrrttrYDIDMTKCIYCGFCQEACP 163
Cdd:PRK09898 121 DTCRQCKepQCMNVCPIGAITWQQKEGC--------ITVDHKRCIGCSACTTACP 167

DMSOR_beta_like

cd16372

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

113-168

1.88e-04

Pssm-ID: 319894 [Multi-domain] Cd Length: 125 Bit Score: 40.01 E-value: 1.88e-04

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 113 CIACKLCEAICPAQAITieaepradgsrRTTR--YDIDMTKCIYCGFCQEACPVDAIV 168
Cdd:cd16372   49 CNQCGECIDVCPTGAIT-----------RDANgvVMINKKLCVGCLMCVGFCPEGAMF 95

DMSOR_beta_like

cd10550

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

111-167

1.90e-04

Pssm-ID: 319872 [Multi-domain] Cd Length: 130 Bit Score: 39.87 E-value: 1.90e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 111 ERCIACKLCEAIC---------PAQA-ITIEAEPRADgsrrttrYDIDMTkCIYCG--FCQEACPVDAI 167
Cdd:cd10550    6 EKCTGCRTCELACslkhegvfnPSLSrIRVVRFEPEG-------LDVPVV-CRQCEdaPCVEACPVGAI 66

PRK06259

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional

91-163

2.17e-04

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional

Pssm-ID: 235756 [Multi-domain] Cd Length: 486 Bit Score: 41.53 E-value: 2.17e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  91 GPLSPRFRGEHALRRYPSGEER------CIACKLCEAICPAQAIT-------------IEAEPRADGSRRTTRYDIDMTK 151
Cdd:PRK06259 107 KSLRNYLQRKNEKITYPEDIEDikklrgCIECLSCVSTCPARKVSdypgptfmrqlarFAFDPRDEGDREKEAFDEGLYN 186

                         90
                 ....*....|..
gi 564332128 152 CIYCGFCQEACP 163
Cdd:PRK06259 187 CTTCGKCVEVCP 198

DMSOR_beta_like

cd16372

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

110-172

2.26e-04

Pssm-ID: 319894 [Multi-domain] Cd Length: 125 Bit Score: 39.63 E-value: 2.26e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564332128 110 EERCIACKLCEAICpaqAITIEAEPRADGSR-RTTRYD--IDMTKCIYCGFCQEACPVDAIVEGPN 172
Cdd:cd16372    7 PEKCIGCLQCEEAC---SKTFFKEEDREKSCiRITETEggYAINVCNQCGECIDVCPTGAITRDAN 69

rnfB

TIGR01944

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...

147-173

2.28e-04

Pssm-ID: 273887 [Multi-domain] Cd Length: 165 Bit Score: 40.17 E-value: 2.28e-04

                          10        20
                  ....*....|....*....|....*..
gi 564332128  147 IDMTKCIYCGFCQEACPVDAIVEGPNF 173
Cdd:TIGR01944 110 IDEDNCIGCTKCIQACPVDAIVGAAKA 136

oorD

PRK09626

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed

110-181

2.53e-04

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed

Pssm-ID: 236597 [Multi-domain] Cd Length: 103 Bit Score: 38.93 E-value: 2.53e-04

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRAD-GSRRTTRYDidmTKCIYCGFCQEACPVDAI--VEGPNFEFSTETHE 181
Cdd:PRK09626  15 ESRCKACDICVSVCPAGVLAMRIDPHAVlGKMIKVVHP---ESCIGCRECELHCPDFAIyvADRKEFKFAKLSKE 86

RDH

TIGR02486

reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S ...

113-163

3.15e-04

reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S cluster-containing reductive dehalogenases found primarily in halorespiring microorganisms such as dehalococcoides ethenogenes which contains as many as 17 enzymes of this type with varying substrate ranges. One example of a characterized species is the tetrachloroethene reductive dehalogenase (1.97.1.8) which also acts on trichloroethene converting it to dichloroethene.

Pssm-ID: 274158 Cd Length: 314 Bit Score: 40.88 E-value: 3.15e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564332128  113 CIACKLCEAICPAQAITIEAEPRADGSRRTTRYD----------IDMTKCI----------YCGFCQEACP 163
Cdd:TIGR02486 207 CETCGKCADECPSGAISKGGEPTWDPEDSNGDPPgennpglkwqYDGWRCLlfrcynegggGCGVCQAVCP 277

DMSOR_beta_like

cd16372

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

102-167

4.15e-04

Pssm-ID: 319894 [Multi-domain] Cd Length: 125 Bit Score: 38.86 E-value: 4.15e-04

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564332128 102 ALRRYPSG-----EERCIACKLCEAICPAQAItIEAEPRadgsrrttrydIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd16372   63 AITRDANGvvminKKLCVGCLMCVGFCPEGAM-FKHEDY-----------PEPFKCIACGICVKACPTGAL 121

DMSOR_beta_like

cd16374

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

111-178

4.19e-04

Pssm-ID: 319896 [Multi-domain] Cd Length: 139 Bit Score: 39.18 E-value: 4.19e-04

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564332128 111 ERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydidMTKCIYCG---------FCQEACPVDAIVEGPNFEFSTE 178
Cdd:cd16374   73 DKCIGCGMCAMACPFGVPRFDPSLKV------------AVKCDLCIdrrregklpACVEACPTGALKFGDIEELLKE 137

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

146-172

6.78e-04

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 38.15 E-value: 6.78e-04

                         10        20
                 ....*....|....*....|....*..
gi 564332128 146 DIDMTKCIYCGFCQEACPVDAIVEGPN 172
Cdd:cd10549    2 KYDPEKCIGCGICVKACPTDAIELGPN 28

Fer4

pfam00037

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...

110-129

7.01e-04

Pssm-ID: 459642 [Multi-domain] Cd Length: 24 Bit Score: 35.69 E-value: 7.01e-04

                          10        20
                  ....*....|....*....|
gi 564332128  110 EERCIACKLCEAICPAQAIT 129
Cdd:pfam00037   5 EEKCIGCGACVEVCPVGAIT 24

DsrA

COG2221

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...

142-167

8.10e-04

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];

Pssm-ID: 441823 [Multi-domain] Cd Length: 69 Bit Score: 36.57 E-value: 8.10e-04

                         10        20
                 ....*....|....*....|....*.
gi 564332128 142 TTRYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:COG2221    7 TWPPKIDEEKCIGCGLCVAVCPTGAI 32

IorA

COG4231

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...

110-136

1.05e-03

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];

Pssm-ID: 443375 [Multi-domain] Cd Length: 76 Bit Score: 36.56 E-value: 1.05e-03

                         10        20
                 ....*....|....*....|....*..
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRA 136
Cdd:COG4231   50 PDLCIGCGSCVQVCPVDAIKLEKRVPE 76

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

110-131

1.08e-03

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 37.76 E-value: 1.08e-03

                         10        20
                 ....*....|....*....|..
gi 564332128 110 EERCIACKLCEAICPAQAITIE 131
Cdd:cd10549  107 KEKCIGCGICAEVCPVNAIKLV 128

PRK06991

electron transport complex subunit RsxB;

147-171

1.09e-03

electron transport complex subunit RsxB;

Pssm-ID: 235903 [Multi-domain] Cd Length: 270 Bit Score: 39.01 E-value: 1.09e-03

                         10        20
                 ....*....|....*....|....*
gi 564332128 147 IDMTKCIYCGFCQEACPVDAIVEGP 171
Cdd:PRK06991  82 IDEQLCIGCTLCMQACPVDAIVGAP 106

PRK12576

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;

63-165

1.30e-03

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;

Pssm-ID: 237143 [Multi-domain] Cd Length: 279 Bit Score: 38.58 E-value: 1.30e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128  63 WTELFRGLGMTLSYLFRepatiNYPFEKGPLSPRFRGEHALRRYPSGEerCIACKLCEAICPAQAITIE----------- 131
Cdd:PRK12576 111 FDEFYERMFKVKPRLYR-----AKEVLEGKAEHRLKPEDQKELWKFAQ--CIWCGLCVSACPVVAIDPEflgpaahakgy 183

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 564332128 132 ---AEPRADGSRRTTRYDIDMT-KCIYCGFCQEACPVD 165
Cdd:PRK12576 184 rflADPRDTITEERMKILIDSSwRCTYCYSCSNVCPRD 221

NapF

COG1145

Ferredoxin [Energy production and conversion];

110-134

1.48e-03

Ferredoxin [Energy production and conversion];

Pssm-ID: 440760 [Multi-domain] Cd Length: 238 Bit Score: 38.55 E-value: 1.48e-03

                         10        20
                 ....*....|....*....|....*
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEP 134
Cdd:COG1145  212 PDKCIGCGACVKVCPVGAISLEPKE 236

CooF_like

cd10563

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...

102-168

1.53e-03

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.

Pssm-ID: 319885 [Multi-domain] Cd Length: 140 Bit Score: 37.62 E-value: 1.53e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 102 ALRRYP-SG-----EERCIACKLCEAICPAQAITIEAEPRAdgsrrttrydidMTKCIYCGF-----CQEACPVDAIV 168
Cdd:cd10563   73 AMHKDPeTGivihdEEKCVGCWMCVMVCPYGAIRPDKERKV------------ALKCDLCPDretpaCVEACPTGALV 138

COG2768

Uncharacterized Fe-S cluster protein [Function unknown];

110-145

1.53e-03

Uncharacterized Fe-S cluster protein [Function unknown];

Pssm-ID: 442050 [Multi-domain] Cd Length: 74 Bit Score: 36.25 E-value: 1.53e-03

                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPRADGSRRTTRY 145
Cdd:COG2768   39 PEKCIGCGACIEVCPVGAIKIEWEEDEEFQEKMAEY 74

FDH_b_like

cd10562

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...

119-167

1.57e-03

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.

Pssm-ID: 319884 [Multi-domain] Cd Length: 161 Bit Score: 37.67 E-value: 1.57e-03

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 564332128 119 CEAICPAQAITIEAepraDGSrrttrYDIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd10562   78 CVKVCPTGALYKTE----NGA-----VVVDEDKCIGCGYCVAACPFDVP 117

RnfB

COG2878

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...

110-169

1.73e-03

Pssm-ID: 442125 [Multi-domain] Cd Length: 254 Bit Score: 38.44 E-value: 1.73e-03

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564332128 110 EERCIACKLCEAICPAQAITIEAEPrADGSRRTTRYDIDMTKCIYC-GFCQEACPVDAIVE 169
Cdd:COG2878  166 EDKCTGCGLCVEACPVDCIEMVPVS-PTVVVSSWDKGKAVRKVVGCiGLCCKKCCPAAAIT 225

Fer4_8

pfam13183

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...

112-165

1.84e-03

Pssm-ID: 433017 [Multi-domain] Cd Length: 64 Bit Score: 35.75 E-value: 1.84e-03

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564332128  112 RCIACKLCEAICPA---------QAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVD 165
Cdd:pfam13183   1 RCIRCGACLAACPVylvtggrfpGDPRGGAAALLGRLEALEGLAEGLWLCTLCGACTEVCPVG 63

PRK05113

electron transport complex protein RnfB; Provisional

147-168

1.91e-03

electron transport complex protein RnfB; Provisional

Pssm-ID: 235347 [Multi-domain] Cd Length: 191 Bit Score: 37.62 E-value: 1.91e-03

                         10        20
                 ....*....|....*....|..
gi 564332128 147 IDMTKCIYCGFCQEACPVDAIV 168
Cdd:PRK05113 111 IDEDNCIGCTKCIQACPVDAIV 132

HycB_like

cd10554

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...

114-167

2.82e-03

Pssm-ID: 319876 [Multi-domain] Cd Length: 149 Bit Score: 36.85 E-value: 2.82e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564332128 114 IACKLCE-----AICPAQAITieaepRADGSRRttrydIDMTKCIYCGFCQEACPVDAI 167
Cdd:cd10554   54 VQCRQCEdapcaNVCPVGAIS-----QEDGVVQ-----VDEERCIGCKLCVLACPFGAI 102

PRK00783

DNA-directed RNA polymerase subunit D; Provisional

110-179

2.95e-03

DNA-directed RNA polymerase subunit D; Provisional

Pssm-ID: 234837 [Multi-domain] Cd Length: 263 Bit Score: 37.56 E-value: 2.95e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564332128 110 EERCIACKLCEAICPAQAITIEaepraDGSRRTTrydiDMTKCIYCGFCQEACPVDAIVEG--PN-FEFSTET 179
Cdd:PRK00783 168 SEDCDECEKCVEACPRGVLELK-----EGKLVVT----DLLNCSLCKLCERACPGKAIRVSddENkFIFTVES 231

FDH_b_like

cd10562

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...

110-171

4.36e-03

Pssm-ID: 319884 [Multi-domain] Cd Length: 161 Bit Score: 36.51 E-value: 4.36e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564332128 110 EERCIACKLCEAICPAQAitieaePRADgsrrttRYDIDMTKCIYC------GF---CQEACPVDAIVEGP 171
Cdd:cd10562   99 EDKCIGCGYCVAACPFDV------PRYD------ETTNKITKCTLCfdrienGMqpaCVKTCPTGALTFGD 157

porD

PRK09625

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed

111-163

4.54e-03

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed

Pssm-ID: 236596 [Multi-domain] Cd Length: 133 Bit Score: 35.88 E-value: 4.54e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 564332128 111 ERCIACKLCEAICPAQAITieaepradgSRRTTRYDIDMTKCIYCGFCQEACP 163
Cdd:PRK09625  59 EICINCFNCWVYCPDAAIL---------SRDKKLKGVDYSHCKGCGVCVEVCP 102

DMSOR_beta_like

cd16369

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

113-163

5.51e-03

Pssm-ID: 319891 [Multi-domain] Cd Length: 172 Bit Score: 36.21 E-value: 5.51e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 564332128 113 CIACKL--CEAICPAQAITIEaeprADGSRRTTrydiDMTKCIYCGFCQEACP 163
Cdd:cd16369   51 CMHCEDptCAEVCPADAIKVT----EDGVVQSA----LKPRCIGCSNCVNACP 95

QueG

COG1600

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and ...

110-163

6.25e-03

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and biogenesis]; Epoxyqueuosine reductase QueG (queuosine biosynthesis) is part of the Pathway/BioSystem: tRNA modification

Pssm-ID: 441208 [Multi-domain] Cd Length: 345 Bit Score: 36.72 E-value: 6.25e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564332128 110 EERCIACKLCEAICPAQAITieaEPradgsrrttrYDIDMTKCI-Y-----------------------CGFCQEACP 163
Cdd:COG1600  183 EDHCGSCTRCLDACPTGAIV---AP----------YVLDARRCIsYltielkgpipeelrpkmgnriygCDDCQDVCP 247

RnfB

COG2878

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...

152-172

6.96e-03

Pssm-ID: 442125 [Multi-domain] Cd Length: 254 Bit Score: 36.51 E-value: 6.96e-03

                         10        20
                 ....*....|....*....|.
gi 564332128 152 CIYCGFCQEACPVDAIVEGPN 172
Cdd:COG2878  139 CIGCGDCIKACPFDAIVGAAK 159

RNAP_D

cd07030

D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is ...

100-179

8.53e-03

D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is involved in the assembly of RNAP subunits. RNAP is a large multi-subunit complex responsible for the synthesis of RNA. It is the principal enzyme of the transcription process, and is a final target in many regulatory pathways that control gene expression in all living cells. A single distinct RNAP complex is found in archaea, which may be responsible for the synthesis of all RNAs. The archaeal RNAP harbors homologues of all eukaryotic RNAP II subunits with two exceptions (RPB8 and RPB9). The 12 archaeal subunits are designated by letters and can be divided into three functional groups that are engaged in: (I) catalysis (A'/A", B'/B" or B); (II) assembly (L, N, D and P); and (III) auxiliary functions (F, E, H and K). The D subunit is equivalent to the RPB3 subunit of eukaryotic RNAP II. It contains two subdomains: one subdomain is similar the eukaryotic Rpb11/AC19/archaeal L subunit which is involved in dimerization, and the other is an inserted beta sheet subdomain. The assembly of the two largest archaeal RNAP subunits that provide most of the enzyme's catalytic functions depends on the presence of the archaeal D/L heterodimer.

Pssm-ID: 132908 [Multi-domain] Cd Length: 259 Bit Score: 36.09 E-value: 8.53e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 100 EHA---------LRRYPSGE--ERCIACKLCEAICPAQAITIEAEPRADGsrrttrydiDMTKCIYCGFCQEACPVDAIV 168
Cdd:cd07030  147 EHAkwqpttacgYKYYPVIEidEDCDGCGKCVEECPRGVLELEEGKVVVE---------DLEDCSLCKLCERACDAGAIR 217

                         90
                 ....*....|....
gi 564332128 169 EGP---NFEFSTET 179
Cdd:cd07030  218 VGWdedRFIFEVES 231

FDH_beta_like

cd16366

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...

102-170

8.58e-03

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.

Pssm-ID: 319888 [Multi-domain] Cd Length: 156 Bit Score: 35.45 E-value: 8.58e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564332128 102 ALRRYPSG-----EERCIACKLCEAICPAQAITIEAEpradgsrrttryDIDMTKCIYC------GF---CQEACPVDAI 167
Cdd:cd16366   86 AIIRTETGtvvvdPETCIGCGYCVNACPFDIPRFDEE------------TGRVAKCTLCydrisnGLqpaCVKTCPTGAL 153


                 ...
gi 564332128 168 VEG 170
Cdd:cd16366  154 TFG 156

Fer4_6

pfam12837

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...

110-128

8.75e-03

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.

Pssm-ID: 432822 [Multi-domain] Cd Length: 24 Bit Score: 32.59 E-value: 8.75e-03

                          10
                  ....*....|....*....
gi 564332128  110 EERCIACKLCEAICPAQAI 128
Cdd:pfam12837   6 PDKCIGCGRCVVVCPYGAI 24

Fer4_6

pfam12837

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...

147-167

8.84e-03

Pssm-ID: 432822 [Multi-domain] Cd Length: 24 Bit Score: 32.59 E-value: 8.84e-03

                          10        20
                  ....*....|....*....|.
gi 564332128  147 IDMTKCIYCGFCQEACPVDAI 167
Cdd:pfam12837   4 VDPDKCIGCGRCVVVCPYGAI 24

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01